991 results match your criteria Pilomatrixoma

A newly growing asymptomatic facial lesion.

Clin Exp Dermatol 2022 Jun 16. Epub 2022 Jun 16.

Departments of Dermatology, Ninewells Hospital and Medical School, Dundee, UK.

A 23-year-old man presenting with a 1-year history of a lesion of the right cheek. We highlight this case for awareness as this tumour may mimic other benign lesions, such as pilomatrixoma or benign cysts, as it does not have any uniquely identifying clinical or dermoscopic features. Additionally, it is of concern as malignant transformation can occur and therefore surgery should be considered as both for diagnostic and therapeutic benefit. Read More

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Rare case of multiple and perforating pilomatrixomas in a young girl with lymphovascular malformation reveals a potential new disease association.

BMJ Case Rep 2022 May 25;15(5). Epub 2022 May 25.

Department of Plastic Surgery, NHS Tayside, Dundee, UK.

This report details the case of a girl of primary school age who was referred to our plastic surgery department with an ulcerating lesion on the nape of her neck. A firm mass was palpable in the underlying subcutaneous tissue. This lesion was accompanied by two smaller firm nodules: one in the adjacent tissue and another in the left preauricular region. Read More

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Pilomatricoma in the neck of an adult male.

Autops Case Rep 2022 28;12:e2021379. Epub 2022 Apr 28.

Cape Coast Teaching Hospital, Department of Pathology, Cape Coast, Ghana.

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Top Advances in Dermatologic Ultrasound.

Ximena Wortsman

J Ultrasound Med 2022 May 10. Epub 2022 May 10.

Institute for Diagnostic Imaging and Research of the Skin and Soft Tissues, Santiago, Chile.

The advances in dermatologic ultrasound have been significantly influenced by the development of high- and ultrahigh-frequency probes, the provision of guidelines for performing the examinations, and a growing number of publications in the field. This review analyzes the most significant contributions that have impacted the daily practice of dermatologists in recent years. This includes the advances in anatomical detection and the patterns of benign and malignant cutaneous tumors, inflammatory dermatologic conditions, vascular anomalies, nail abnormalities, and aesthetic procedures. Read More

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Rare and unusual benign tumors of the sinonasal tract and pharynx: Case series and literature review.

Exp Ther Med 2022 May 16;23(5):334. Epub 2022 Mar 16.

Medical Clinical Department, Faculty of Medicine and Pharmacy, 'Dunărea de Jos' University, 800008 Galați, Romania.

There are a number of benign tumors of the nose and pharynx that are seldomly reported in literature but that can sometimes prove difficult to treat and extremely important for differential diagnosis. The present study presents cases of rare benign tumors localized in the pharynx, nasal and sinus cavities, as well as reviews of literature and historical references for each type of tumor. Unilateral nasal hemangioma in a 72-year-old male which, although not a rare pathology, raised problems due to auto-resection of the tumor. Read More

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Ghost cells unveiled: A comprehensive review.

J Oral Biosci 2022 06 6;64(2):202-209. Epub 2022 Apr 6.

Head of Department of Oral Pathology, Maulana Azad Institute of Dental Sciences, New Delhi 110002, India. Electronic address:

Background: Ghost cells (GCs) are cells with distinct intracytoplasmic keratinization, which leads to the preservation of the cellular outline with a clear area corresponding to the previous nucleus location. GCs may show various patterns, such as degeneration, tissue granulation, and calcification. Their true nature and the mechanism regulating the conversion of odontogenic epithelial cells into GCs remain unclear. Read More

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Clinicopathological Features of 19 Eyelid Pilomatrixomas.

Ocul Oncol Pathol 2022 Feb 25;8(1):30-34. Epub 2021 Oct 25.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Introduction: Pilomatrixoma is a relatively rare, benign tumor arising from the hair root matrix. It is found frequently on the head and neck, with most involving the eyebrow in the periocular region. In contrast, eyelid pilomatrixoma is less common, and often clinically misdiagnosed. Read More

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February 2022

Giant Pilomatrixoma of the Scrotum: A Rare Case Presentation.

Cureus 2022 Feb 15;14(2):e22228. Epub 2022 Feb 15.

Department of Surgery, Dr. Hedgewar Hospital, Aurangabad, IND.

Pilomatrixoma is a benign adnexal skin tumor involving the hair follicle matrix. It is found in children, predominantly involving the face. We report here an interesting and rare case of a 52-year-old male presenting with a large, firm, and painless mass over the scrotum considered to be a sebaceous cyst. Read More

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February 2022

Giant pilomatrixoma with bullous appearance on the back: A case report and discussion of misdiagnosis.

J Cosmet Dermatol 2022 Mar 25. Epub 2022 Mar 25.

Department of Ultrasound, Peking Union Medical College Hospital, Beijing, China.

Pilomatrixoma is a benign, asymptomatic skin tumor that forms from hair follicle matrix cells. Most are under 3 cm in diameter and occur on the head, face, or neck. Bullous appearance is very rare in pilomatrixoma. Read More

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Melanocytic matricoma: A report of three cases, review of the literature, and suggestion of a new terminology.

J Cutan Pathol 2022 Jul 14;49(7):645-650. Epub 2022 Mar 14.

Department of Pathology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

Melanocytic matricoma is a rare, biphasic adnexal tumor. It typically presents as a pigmented papule on the sun-damaged skin of elderly patients. Histopathology shows a dermal nodule composed of basaloid cells, ghost cells, and deeply pigmented dendritic melanocytes. Read More

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Multiple pilomatricomas in a child with xeroderma pigmentosum: Coincidence or association?

Pediatr Dermatol 2022 Feb 17. Epub 2022 Feb 17.

Department of Dermatology, Hospital Universitari i Politècnic La Fe, Valencia, Spain.

The association of multiple pilomatricomas with xeroderma pigmentosum has not been described. We report a case of a child with multiple pilomatricomas and photosensitivity who was found to have a pathogenic variant in exon 4 of XPA and a likely pathogenic variant in COL6A1. Read More

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February 2022

A case of multiple perforating pilomatricomas.

An Bras Dermatol 2022 Mar-Apr;97(2):263-264. Epub 2022 Feb 10.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.

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Ossifying pilomatricoma and a novel hypothesis for its pathogenesis: A case report and comprehensive literature review.

Medicine (Baltimore) 2022 Feb;101(6):e28753

Department of Plastic and Reconstructive Surgery, Kangwon National University Hospital, Chuncheon, Republic of Korea.

Rationale: Pilomatricoma is a benign skin appendageal tumor derived from hair follicle matrix cells that commonly affects the head, neck, and upper extremities of the pediatric population. Since the original tumor description, diverse variants have been reported in the literature. Pilomatricoma with florid osseous metaplasia is described as an ossifying pilomatricoma and is recognized as a distinct variant of this benign tumor. Read More

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February 2022

Pilomatrical Acanthoma: An Extremely Rare Intraepidermal Variant of Pilomatricoma.

Am J Dermatopathol 2022 Jun 2;44(6):433-436. Epub 2022 Feb 2.

Department of Pathology, University of Texas Southwestern Medical Center,Dallas, TX; and.

Abstract: Pilomatrical differentiation can be observed in a variety of benign and malignant tumors, with the most common prototype being pilomatricoma. Pilomatricoma often presents in the deep dermis or subcutis, and the sole involvement of epidermis is extremely rare. In our current case series, specimens from 5 patients were included with an average age of 68 years. Read More

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Pilomatrixoma Recurring as Giant Form.

Cureus 2022 Jan 17;14(1):e21308. Epub 2022 Jan 17.

Head and Neck Surgery Department, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, PRT.

Pilomatrixoma is a benign skin tumor that originates from the hair matrix. It usually appears in children and young adults and is preferably in the head and neck region. It clinically presents as an asymptomatic firm, solitary subcutaneous mass of less than 3 cm. Read More

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January 2022

[Benign skin neoplasms in children].

Hautarzt 2022 Feb 14;73(2):127-137. Epub 2022 Jan 14.

Dermatologie II, Colentina Klinik, Carol-Davila-Universität für Medizin und Pharmazie, Stefan cel Mare Street 19-21, 020125, Bukarest, Rumänien.

There are many different types of skin neoplasms in children and most are benign. Dermatologists should be able to differentiate between the various types of benign skin neoplasms and be able to recommend optimal treatment to concerned patients. Surgical removal of benign skin neoplasms is often the only treatment option. Read More

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February 2022

Melanocytic Panfolliculoma: A Case Report of a Rare Benign Follicular Tumor.

Am J Dermatopathol 2022 Apr;44(4):276-278

ProPath Dermatopathology, Dallas TX.

Abstract: Panfolliculomas (PF) are rare, benign, follicular tumors that differentiate toward multiple components of the hair follicle, and several variants have been described. We present a case of a rare pigmented PF presenting on actinically damaged skin in an 83-year-old man, which was clinically concerning for malignancy. This tumor arose near an area of atypical squamous proliferation and has evidence of infundibular, outer root sheath, and matrical differentiation and foci of heavy melanin pigmentation and increased melanocytes. Read More

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Pilomatrixoma: A Masquerader at Uncommon Sites.

J Indian Assoc Pediatr Surg 2021 Nov-Dec;26(6):462-463. Epub 2021 Nov 12.

Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India.

The rarity, diverse clinical presentation, relatively featureless sonography, and diagnostic dilemma associated with pilomatrixomas may trigger anxiety and call for unwarranted investigations. The authors have shared their experience in two consecutive cases to generate awareness for such lesions. Read More

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November 2021

Early Pilomatrix Carcinoma: A Case Report With Emphasis on Molecular Pathology and Review of the Literature.

Cutis 2021 Oct;108(4):E24-E28

Drs. Kamil and Ghazarian and Mr. Sachdeva are from the University of Toronto, Ontario, Canada. Drs. Kamil and Ghazarian are from the Department of Laboratory Medicine and Pathobiology. Drs. Kamil and Ghazarian also are from the Department of Laboratory Medicine and Pathobiology, University Health Network, Toronto. Dr. Kwapis is from Sensenbrenner Hospital, Kapuskasing, Ontario, and McMaster University, Hamilton, Ontario.

Pilomatrix carcinoma is a rare adnexal tumor with origin from the germinative matrical cells of the hair follicle. Clinically, it presents as a solitary lesion commonly found in the head and neck region and upper back. The tumors cannot be distinguished by their clinical appearance only and frequently are mistaken for cysts. Read More

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October 2021

CDX2 and SATB2 positivity in pilomatrix carcinoma: Avoiding an erroneous diagnosis of cutaneous metastasis of gastrointestinal origin.

J Cutan Pathol 2022 Apr 2;49(4):399-402. Epub 2021 Dec 2.

Department of Pathology and Laboratory Medicine, Saskatchewan Health Authority, Saskatoon, Saskatchewan, Canada.

An 80-year-old female presented with a slowly growing 2-cm nodule on her shoulder over a 1-year period. Histopathologic sections of a biopsy specimen showed a multinodular, dermal-based basaloid tumor with areas of clear-cell change, stromal induction, as well as significant cytologic atypia and atypical mitotic activity. An initial investigation revealed positive staining of CDX2, a well-known marker of tumors of gastrointestinal origin. Read More

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Dermoscopic Differentiation of Pilomatricoma From Pilomatrical Carcinoma.

Dermatol Surg 2021 12;47(12):1657-1658

Institute of Pathology, Faculty of Medicine, University of Belgrade, Serbia.

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December 2021

Pilomatrixoma and its Imitators.

Ear Nose Throat J 2021 Sep 22:1455613211044778. Epub 2021 Sep 22.

Departments of Otolaryngology--Head & Neck Surgery, 12314Lewis Katz School of Medicine at Temple University, Philadelphia, PA, USA.

Pilomatrixomas are benign neoplasms derived from hair follicle matrix cells. They are among the most common soft tissue head and neck tumors of childhood. Pilomatrixomas are typically isolated, slow-growing, firm, nontender masses that are adherent to the epidermis but mobile in the subcutaneous plane. Read More

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September 2021

A 5-year retrospective review of skin adnexal tumours received at a tertiary dermatopathology service: implications for linked genetic diagnoses.

Br J Dermatol 2022 01 21;186(1):167-173. Epub 2021 Oct 21.

Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

Background: Skin adnexal tumours (SATs) comprise a diverse range of neoplasms, which are difficult to diagnose clinically. They present in paediatric and adult populations, and may be indicative of an underlying genetic syndrome. There is a lack of recent data on the presentation of these tumours in clinical practice in European populations. Read More

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January 2022

Pilomatrix carcinoma: a rare cutaneous adnexal tumor.

Dermatol Online J 2021 Jun 15;27(6). Epub 2021 Jun 15.

Dermatology Clinic, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari.

Pilomatrix carcinoma is a rare tumor that is generally not diagnosed clinically. An 80-year-old man presented with a 5-month history of rapidly growing nodule of the submandibular area. Histological examination revealed a pilomatrix carcinoma, an aggressive malignancy with metastatic potential. Read More

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Pilomatrixoma mimicking a breast neoplasm: imaging finding in an uncommon case report.

Radiol Case Rep 2021 Sep 1;16(9):2357-2361. Epub 2021 Jul 1.

Department of Radiology, CHU Hassan II, FEZ, Sidi Mohammed Ben Abdellah University, Morocco.

Pilomatrixoma is a rare benign skin tumor originating from piliferous follicles, corresponding to a firm subcutaneous nodule requiring histology for diagnosis. Breast localization is considered to be very rare . Only few breast pilomatricomas have been reported, with imaging showing well defined nodules with microcalcifications, presenting as ACR BI-RADS 4 and 5, suspicious for a breast neoplasm . Read More

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September 2021

Giant Pilomatrical Tumor With Broad Epidermal Components: An Example of Histological Diversity and a Potential Diagnostic Pitfall of Tumors With Pilomatrical Differentiation.

Am J Dermatopathol 2022 Feb;44(2):129-134

Departments of Diagnostic Pathology, and.

Abstract: The diagnosis of pilomatricoma, the most common matrical tumor, is generally straightforward; however, it exhibits diverse histology associated with various morphological stages and several clinical variants, and matrical differentiation can occur in various neoplastic diseases. A 56-year-old man was admitted to our hospital to resect an 11.0-cm skin tumor on his right shoulder. Read More

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February 2022

Apocrine mixed tumor with pilomatrical differentiation.

J Cutan Pathol 2021 11 29;48(11):1427-1429. Epub 2021 Jul 29.

Department of Pathology, UT Southwestern Medical Center, Dallas, Texas, USA.

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November 2021

Ultrasound findings in 156 children with 169 pilomatricomas.

Pediatr Radiol 2021 Oct 13;51(11):2038-2046. Epub 2021 Jul 13.

Universidad Católica de Córdoba, Ciudad de Córdoba, República Argentina.

Background: Cutaneous lesions present a diagnostic challenge to radiologists and clinicians alike. Pilomatricoma is the second most common skin neoplasm in childhood, yet there are limited reports in the literature focusing on imaging in pediatric patients.

Objective: To characterize the typical and atypical US features of pilomatricoma in pediatric patients and to determine the performance of the adult-based Solivetti classification for assessing pilomatricomas in children. Read More

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October 2021

Nodular Mass in the Earlobe of an 18-Month-Old Girl.

JAMA Otolaryngol Head Neck Surg 2021 09;147(9):824-825

Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.

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September 2021

Huge pilomatrixomas of the scalp: A case report.

Int J Surg Case Rep 2021 Jul 29;84:106048. Epub 2021 May 29.

ENT Department, Face and Neck Surgery, Hospital August, 20, 1953, University Hospital Center IBN ROCHD, Casablanca, Morocco; Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Pilomatrixoma is a rare benign skin tumor differentiating toward hair matrix cells usually encountered in the head and neck region. It is most frequently appearing in the first and second decades of life. Histopathological examination is essential to make definitive diagnosis. Read More

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