118 results match your criteria Pigmented Lesions of the Eyelid


Conjunctival melanocytic naevus: Diagnostic value of anterior segment optical coherence tomography and ultrasound biomicroscopy.

PLoS One 2018 14;13(2):e0192908. Epub 2018 Feb 14.

University of Szeged, Department of Ophthalmology, Szeged, Hungary.

Purpose: Conjunctival naevi are the most frequently diagnosed primary melanocytic lesions of the conjunctiva. The clinical manifestations are greatly variable which may result in diagnostic difficulties and differential diagnostic confusions. Therefore aims of the present study were: 1) to assess the morphologic features of conjunctival naevi; 2) to delineate the anterior segment optical coherence tomography (AS-OCT) characteristics of these lesions; 3) to compare AS-OCT and ultrasound biomicroscopy (UBM) as diagnostic tools in these alterations and 4) to correlate histological results with the AS-OCT pictures in case of surgically excised naevi. Read More

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Primary Cutaneous Mucinous Carcinoma of the Eyelid.

Arch Craniofac Surg 2016 Sep 23;17(3):176-179. Epub 2016 Sep 23.

Department of Pathology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.

Primary cutaneous mucinous carcinoma (PCMC) is a rare low-grade malignant neoplasm derived from the eccrine glands. PCMC most commonly arises in the head and neck, with the eyelid being the most common site of origin. This case report describes a 51-year-old male with a painless, pigmented superficial nodular lesion over his right lower eyelid. Read More

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September 2016
4 Reads

Pigmented tumors in fallow deer ( Dama dama): 11 cases.

J Vet Diagn Invest 2017 Jul 3;29(4):483-488. Epub 2017 May 3.

Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado (Hughes).

Pigmented tumors have been reported infrequently in captive deer. We document herein the clinical progression and gross and histopathologic features of pigmented tumors diagnosed as melanoma and pigmented schwannoma in 11 white fallow deer ( Dama dama). Affected animals were part of a captive herd maintained at a drive-through park in southern Oregon and were 5-17 y of age during the study period (2004-2013). Read More

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July 2017
2 Reads

Ocular Argyrosis Mimicking Conjunctival Melanoma.

Cornea 2017 Jun;36(6):747-748

*Ophthalmic Oncology Service, Memorial Sloan-Kettering Cancer Center, New York, NY; †Department of Ophthalmology, Weill Cornell Medical College, New York, NY; ‡Department of Pathology, Dermatopathology Service, Memorial Sloan-Kettering Cancer Center, New York, NY; and §Pathology and Laboratory Services, Duke University Health System, Durham, NC.

Purpose: To present a novel case of ocular argyrosis mimicking conjunctival melanoma.

Methods: A 48-year-old man who is a jewelry manufacturer presented with raised pigmented lesions in the inferior fornices of both eyes. Brown-black colored, follicle-like, masses were observed in both fornices. Read More

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June 2017
2 Reads

Corneal Involvement by Lichen Planus Pigmentosus.

Ocul Immunol Inflamm 2017 Feb 1:1-3. Epub 2017 Feb 1.

b Shahid Beheshti Hospital, Kashan University of Medical Sciences , Kashan , Iran.

Importance: Lichen planus pigmentosus (LPP) is an exclusive form of lichen planus (LP) characterized by pigmentary incontinence in histopathologic slides.

Observations: We report a known case of LPP with ocular manifestations including pigmented eyelid margins and conjunctival and corneal pigmented lesions. Histopathologic and confocal scanning findings of these lesions were compatible with the diagnosis of underlying systemic disease. Read More

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February 2017
3 Reads

Eyelid metastasis as first presentation of renal cell carcinoma.

Arch Soc Esp Oftalmol 2017 Nov 5;92(11):547-551. Epub 2017 Jan 5.

Departamento de Anatomía Patológica, Hospital Virgen de los Lirios, Alcoy, Alicante, España.

Case Report: An 87-year-old male presented with a slow-growing, painless and well defined nodule in the upper eyelid. The tumour measured 1cm, and was pigmented and adhered to deep planes. The histopathology analysis was compatible with renal cell carcinoma. Read More

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November 2017
1 Read

[Congenital "kissing" lesions: Nevus or "café au lait" spot?]

Rev Stomatol Chir Maxillofac Chir Orale 2016 Dec 4;117(6):433-437. Epub 2016 Oct 4.

Service de chirurgie maxillo-faciale et plastique, hôpital Necker-Enfants-Malades, AP-HP, 149, rue de Sèvres, 75015 Paris, France; Centre de référence des malformations faciales et de la cavité buccale, MAFACE, AP-HP, 75015 Paris, France; Université Paris Descartes, 75005 Paris, France. Electronic address:

Introduction: "Café au lait" spots (CLS) are pigmented skin lesions principally located at the trunk and the limbs. Histologically, CLSs consist in an excessive pigmentation of the epidermis, with no risk of malignant transformation. The "kissing" nevus is a rare pigmented congenital nevus affecting both lower and upper eyelids in a mirror layout. Read More

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December 2016
3 Reads

Melanocytic Nevus of the Tarsal Conjunctiva.

Balkan Med J 2016 Jul 1;33(4):477-9. Epub 2016 Jul 1.

Bursa Pathology Center, Bursa, Turkey.

Background: Melanocytic nevus is a rare occurrence in the tarsal conjunctiva and only 7 well-described cases have been reported previously in the English literature.

Case Report: The medical records of 4 patients with tarsal conjunctival melanocytic nevus were reviewed, together with the relevant literature. All patients (3 women and 1 man; age range: 17 - 40 years) had been referred with a suspicion of melanoma. Read More

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July 2016
1 Read

Argon Laser Photoablation for Treating Benign Pigmented Conjunctival Nevi.

Middle East Afr J Ophthalmol 2016 Jul-Sep;23(3):247-9

Department of Research, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.

Purpose: To evaluate the outcomes of argon laser photoablation of benign conjunctival pigmented nevi with different clinical presentations.

Patients And Methods: This interventional case series was conducted between July 2014 and January 2015. Patients presenting with benign conjunctival nevi were included. Read More

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March 2017
8 Reads

Spitz nevus arising in the eyelid of a teenager.

Surv Ophthalmol 2016 Mar-Apr;61(2):228-35. Epub 2015 Oct 22.

Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA; Department of Ophthalmology, Ophthalmic Plastic Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, USA.

A 16-year-old boy developed over a 2-month interval a lightly pigmented left upper eyelid lesion measuring 1.5 mm in greatest diameter that, when excised, microscopically was hypercellular and composed almost exclusively of nonpigmented epithelioid cells that created florid, large intraepidermal junctional nests and sheets and nests of subepidermal cells. The diagnosis was a Spitz nevus. Read More

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September 2016
1 Read

Technical note: Digital quantification of eye pigmentation of cattle with white faces.

J Anim Sci 2015 Jul;93(7):3654-60

Cancer of the eye in cattle with white faces occurs less frequently in cattle with pigmented eyelids. Corneoscleral pigmentation is related to eyelid pigmentation and occurrence of lesions that may precede cancer. Objectives of this study were to assess 1) variation in the proportion of eyelid and corneoscleral pigmentation in Hereford, Bos taurus, and Bos indicus crossbreds and 2) the occurrence of lesions with the presence of pigmentation in those areas. Read More

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July 2015
1 Read

Kissing naevus arising from neural crest cells presenting as upper and the lower lid mass.

J Neurosci Rural Pract 2015 Jul-Sep;6(3):417-9

Department of Plastic Surgery, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

A kissing nevus is a type of congenital compound nevus that affects equal portions of the upper and lower eyelid, and it extends to the lid margins. Congenital divided nevi of the eyelids are a rare melanocytic lesion. Only 30 patients are reported in the literature. Read More

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July 2015
2 Reads

High-Resolution Optical Coherence Tomography as an Adjunctive Tool in the Diagnosis of Corneal and Conjunctival Pathology.

Ocul Surf 2015 Jul 6;13(3):226-35. Epub 2015 Apr 6.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA. Electronic address:

Purpose: To evaluate the use of a commercially available, high-resolution, spectral-domain optical coherence tomography (HR-OCT) device in the diagnosis of corneal and conjunctival pathologies, with a focus on malignant lesions.

Methods: Eighty-two eyes of 71 patients were enrolled in this prospective case series, including 10 normal eyes, 21 with ocular surface squamous neoplasia (OSSN), 24 with a pterygium or pingueculum, 3 with lymphoma, 18 with pigmented conjunctival lesions (nevus, flat melanosis, or melanoma), and 6 with Salzmann nodular degeneration. Subjects were imaged using photography and HR-OCT (RTVue, Optovue, Fremont, CA). Read More

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July 2015
4 Reads

Large Congenital Melanocytic Nevus on the Breast Sparing the Nipple and Areola.

Pediatr Dermatol 2015 Jul-Aug;32(4):514-7. Epub 2015 May 4.

Department of Dermatology and Venereology, Istanbul Medical Faculty, Istanbul University, Istanbul, Turkey.

Background: Divided nevus is a rare entity that has been described for a special appearance of congenital melanocytic nevi (CMNs) occurring on the eyelid and penis. It is presumed that the formation of divided nevi is related with the embryologic development of the eyelid and penis, thus giving a hint about the occurrence time of CMN in utero. This article focuses on a formerly undescribed observation of another special clinical appearance of CMN discussing possible relation with embryogenesis. Read More

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April 2016
2 Reads

Clinical and histologic description of ocular anatomy in captive black-tailed prairie dogs (Cynomys ludovicianus).

Vet Ophthalmol 2016 Mar 19;19(2):110-6. Epub 2015 Mar 19.

Department of Diagnostic Medicine/Pathobiology, Kansas State University, Manhattan, KS, USA.

Objective: To describe the clinical and histologic ocular anatomy of the black-tailed prairie dog (PD).

Animals Studied: Seventeen captive black-tailed PDs (11 males and six females), ranging in age from approximately 4 months to 4.5 years. Read More

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March 2016
1 Read

Laser treatment of periocular skin conditions.

Clin Dermatol 2015 Mar-Apr;33(2):197-206

Department of Dermatology, University of Connecticut Health Center, 21 South Road, Farmington, Connecticut. Electronic address:

Advances in laser technology in recent decades have increased the options for the treatment of dermatologic conditions of the eye and eyelid. Benign tumors can be laser-ablated with relative ease, and vascular and melanocytic lesions can be precisely targeted with modern lasers. In this contribution, we review treatment of periocular pigmented lesions, including melanocytic nevi and nevus of Ota; vascular lesions including telangiectasias, port wine stains, and infantile hemangiomas; hair removal; eyeliner tattoo removal; laser ablation of common benign periocular tumors, such as syringomas, xanthelasma, milia, and seborrheic keratoses; and laser resurfacing. Read More

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December 2015
9 Reads

Combination topical therapy for conjunctival primary acquired melanosis with atypia and periocular lentigo maligna.

Cornea 2015 Jan;34(1):90-3

*Department of Ophthalmology, University of Colorado, Aurora, CO; †Department of Dermatology, University of Colorado, Aurora, CO; ‡Texas Oculoplastic Consultants, Austin, TX; §Department of Ophthalmology, Division of Corneal and External Disease, University of Colorado, Aurora, CO; and ¶Department of Moh's Micrographic Surgery, University of Colorado, Aurora, CO.

Purpose: To report the case of a patient who initially presented with primary acquired melanosis (PAM) without atypia of the conjunctiva and later developed lentigo maligna of the eyelids and PAM with atypia of the conjunctiva. We illustrate the utility of combination topical therapy with adjunctive cryotherapy to treat extensive eyelid and conjunctival lesions.

Methods: Case report with a review of the current literature. Read More

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January 2015
1 Read

Conjunctival Pigmentation Following Minocycline Therapy.

Ophthalmic Plast Reconstr Surg 2016 Nov/Dec;32(6):e129-e130

*Department of Ophthalmology, Louisiana State University Health Sciences Center; †Department of Ophthalmology, Ochsner Clinic Foundation, New Orleans, Louisiana, U.S.A.; and ‡Charlotte Eye Ear Nose & Throat Associates, Charlotte, North Carolina, U.S.A.

Minocycline is a tetracycline antibiotic commonly used to treat acne and rosacea. Although pigmentation of the skin, nails, teeth, oral mucosa, and sclera is a well-recognized adverse outcome associated with minocycline, ocular pigmentation may be missed on routine examination. The authors present a case of a 43-year-old white woman who demonstrated bilateral pigmented palpebral conjunctival cysts after 12 months of minocycline therapy for cystic acne. Read More

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February 2017
1 Read

Kissing nevus of the penis. Report of two cases and review of the literature.

An Bras Dermatol 2014 Mar-Apr;89(2):329-31

The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Kissing nevus is a curious type of nevus that was first described on the eyelids and rarely described on the penis. We report two cases of kissing nevus of the penis and review previously reported cases. The lesions of the kissing nevus of the penis showed characteristic mirror-image symmetry relative to the coronal sulcus. Read More

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September 2014
2 Reads

Intense pulsed light therapy (IPL) induced iritis following treatment for a medial canthal capillary malformation.

Australas J Dermatol 2014 Nov 14;55(4):289-91. Epub 2014 Jan 14.

Department of Ophthalmology, Flinders Medical Centre, University of Adelaide, South Australia, Australia.

The popularity of intense pulsed light (IPL) therapy continues to increase due to its relative safety, high skin coverage rate and ability to treat both vascular and pigmented lesions. An often-overlooked risk is the potential for IPL-induced ocular damage. The damage sustained can cause significant, persistent morbidity and can occur even with very limited IPL exposure to the eye. Read More

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November 2014
2 Reads

Primary orbital melanoma combined with giant divided nevus of the eyelid.

J Craniofac Surg 2014 Jan;25(1):e4-7

From the *Tianjin Medical University Eye Hospital, Tianjin Medical University Eye Institute; †Tianjin Medical University Eye Hospital; ‡Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin Eye Institute, Clinical College of Ophthalmology Tianjin Medical University; and §Pathology Department, Tianjin Medical University General Hospital, Tianjin, China.

The authors report a rare case of primary orbital melanoma (POM) combined with giant divided nevus of the eyelid. An 8-year-old Chinese girl is referred for evaluation of 2-month duration of exophthalmos with decreased vision, epiphora, and pain on her right eye. His presentation, imaging, biopsy, histopathology, and management are presented. Read More

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January 2014
3 Reads

Divided or kissing nevus of the penis.

Dermatol Online J 2013 Oct 16;19(10):20027. Epub 2013 Oct 16.

Fort Belvoir Community Hospital.

The divided or kissing nevus is an unusual congenital melanocytic nevus. By definition, these nevi appear on skin that separates during embryological development. These lesions have been reported on the eyelids, fingers, and rarely the penis. Read More

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October 2013
6 Reads

Eyelid masses: a 10-year survey from a tertiary eye hospital in Tehran.

Middle East Afr J Ophthalmol 2013 Jul-Sep;20(3):187-92

Ophthalmic Research Center, Shahid Beheshti Medical University, Department of Ophthalmology, Labbafinejad Hospital, Tehran, Iran.

Purpose: The purpose of this study was to evaluate the demographics and clinical features of eyelid masses in a tertiary eye hospital over a 10-year period.

Materials And Methods: A retrospective chart review was performed for patients admitted with eyelid tumors from 2000 to 2010. Data were collected and analyzed on the demographic features, location of the tumor, types of treatment, and pathologic findings. Read More

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January 2014
2 Reads

Divided eyelid nevus: a lid-sparing, staged surgical approach.

Am J Ophthalmol 2013 Oct 24;156(4):813-18. Epub 2013 Jul 24.

Department of Ophthalmology and Visual Sciences, Washington University, St. Louis, Missouri. Electronic address:

Purpose: To describe a method for staged partial resection of congenital divided eyelid nevus. The rationale, technique, and outcomes for this approach are described.

Design: Retrospective chart review of a case series. Read More

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October 2013
2 Reads

Squamous cell carcinoma of the lower eyelid penetrating into the orbit - case report.

Klin Oczna 2013 ;115(1):48-50

Department of Pediatric Ophthalmology with Centre for Treatment of Strabismus, Medical University of Bialystok, Poland.

The aim of our study is to report a case of pigmented squamous cell carcinoma of the palpebral conjunctiva referred to our clinic because of eye pain. A 86 year old patient suffering from eye pain due to a lower right eyelid tumour was admitted to our department. The basic ophthalmic examination and CT scans of orbits were performed. Read More

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August 2013
6 Reads

The complex of myxomas, spotty skin pigmentation and endocrine overactivity (Carney complex): imaging findings with clinical and pathological correlation.

Insights Imaging 2013 Feb 12;4(1):119-33. Epub 2013 Jan 12.

Department of Radiology and Medical Imaging, University Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, 68100, Greece,

The complex of myxomas, spotty skin pigmentation and endocrine overactivity, or Carney complex (CNC), is a familial multiple endocrine neoplasia and lentiginosis syndrome. CNC is inherited in an autosomal dominant manner and is genetically heterogeneous. Its features overlap those of McCune-Albright syndrome and other multiple endocrine neoplasia (MEN) syndromes. Read More

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February 2013
5 Reads

An unusual case of ocular melanosis and limbal melanocytoma with benign intraorbital extension in a dog.

Vet Ophthalmol 2013 Jul 7;16 Suppl 1:117-22. Epub 2012 Nov 7.

Eye Care for Animals, 1021 E. 3300 S., Salt Lake City, UT 84106, USA.

This case report describes concurrent ocular melanosis and limbal melanocytoma in a 6-year-old Golden Retriever dog. Three years prior, the pet was examined for progressive corneal pigmentation and started on topical Tacrolimus but was subsequently lost to followup. Current ophthalmic examination revealed a large pigmented limbal mass and severe corneal pigmentation of the left eye as well as a small focal raised pigmented mass of the right third eyelid. Read More

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July 2013
13 Reads

Malignant transformation of a putative eyelid papilloma to squamous cell carcinoma in a dog.

Vet Ophthalmol 2013 Jul 9;16 Suppl 1:105-12. Epub 2012 Aug 9.

Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA.

A 6-year-old female spayed Chihuahua was presented for the evaluation of generalized pigmented cutaneous masses, one of which was present on the lower right eyelid. The dog was not on immunosuppressive medications and did not have historical or laboratory evidence of underlying endocrine disease, including hypothyroidism and hyperadrenocorticism. Histopathology, immunohistochemistry, and polymerase chain reaction of a cutaneous biopsy from the left antebrachium containing representative lesions confirmed viral papillomatosis. Read More

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July 2013
2 Reads

Malignant transformation of kissing nevus- a rare entity.

Nepal J Ophthalmol 2012 Jul-Dec;4(2):329-32

Department of Ophthalmology, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.

Background: Kissing nevus is a congenital nevus in adjacent parts of the eyelids. Malignant transformation of kissing or divided nevi of the eyelids is rarely described.

Objective: To report a very rare case of malignant transformation of kissing nevus with ocular and extraocular spread. Read More

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July 2013
2 Reads

Orbital myiasis complicating squamous cell carcinoma in xeroderma pigmentosum.

Orbit 2012 Apr;31(2):137-9

Guru Nanak Eye Centre, Maulana Azad Medical College, New Delhi, India.

Ophthalmomyiasis is a rare infection seen in susceptible individuals. We report a case of orbital myiasis in squamous cell carcinoma (SCC) in a patient of xeroderma pigmentosum. On presentation, reddish brown ulcerated mass with numerous maggots in orbit were seen. Read More

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April 2012
3 Reads

Long-term outcomes of surgical management in the patients with facial congenital melanocytic nevi.

J Med Assoc Thai 2011 Dec;94 Suppl 6:S70-8

Division of Plastic Surgery, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Background: The challenges of management of facial congenital melanocytic nevi (CMN) are the balance of the risk of malignant transformation, surgical management and the long-term evaluation of the functional and cosmetic outcomes.

Objective: To present information on the long-term surgical management outcomes of patients with facial CMN, which may be applicable for future clinical and surgical approaches for these lesions.

Material And Method: A follow-up study was performed of patients with facial CMN that were clinically evaluated by the author at Srinagarind Hospital, Khon Kaen University, between 1993 and 2011. Read More

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December 2011
1 Read

Unilateral non-pigmented palpebral conjunctival lesions due to cosmetics use.

Ophthalmic Plast Reconstr Surg 2012 Sep-Oct;28(5):e107-8

Wills Eye Institute, Wills Eye Institute, Philadelphia, Pennsylvania 19057, USA.

A 62-year-old woman with a history of dry eyes was found to have unilateral pedunculated, nonpigmented palpebral conjunctival lesions. Excisional biopsy was performed, and the lesions were studied histopathologically. Microscopic examination of the lesions demonstrated exuberant granulation tissue with a granulomatous foreign body giant cell reaction surrounding pigmented and partially birefringent foreign material. Read More

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December 2012
2 Reads

Clinicopathologic and immunohistochemical features of pigmented Basal cell carcinomas of the eyelids.

Am J Ophthalmol 2012 Feb 6;153(2):242-252.e2. Epub 2011 Oct 6.

David G. Cogan Ophthalmic Pathology Laboratory, Massachusetts Eye and Ear Infirmary, Room 321, 243 Charles St, Boston, MA 02114, USA.

Purpose: To describe the clinical and microscopic features of pigmented basal cell carcinomas (pBCC) of the eyelid.

Design: Retrospective observational case series collected at one institution.

Methods: An analysis of clinical records, photographs, and histopathologic characteristics of 257 BCCs with a review of the literature. Read More

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February 2012
1 Read

Necrotic dermatitis in waterfowl associated with consumption of perennial rye grass (Lolium perenne).

J Avian Med Surg 2011 Mar;25(1):44-9

Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Iran.

Mute swans (Cygnus olor), whooper swans (Cygnus cygnus), and mixed-breed domestic geese (Anser anser domesticus) were presented for necrotic lesions on the feet, eyelids, and beak. Individuals from the same collection of birds had developed identical lesions during March-September of each of the previous 3 years. Vesicular and necrotic dermatitis involved only nonfeathered and nonpigmented areas of the integument. Read More

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March 2011
1 Read

Clinicopathological characteristics and surgical outcomes of divided nevus of the eyelids: a decade's experience on 73 cases.

Ann Plast Surg 2012 Feb;68(2):166-70

Department of Ophthalmology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

Currently, there is a lack of comprehensive data regarding clinicopathologic characteristics and surgical treatment of divided nevus of the eyelids. Here clinicopathologic features and reconstructive procedures performed on 73 patients were described. We showed that the lesion was randomly located on both eyes with a predominant incidence in females. Read More

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February 2012
2 Reads

Congenital melanocytic nevus of upper eyelid.

J Cutan Aesthet Surg 2011 Jan;4(1):61-4

Department of Oral and Maxillofacial Surgery, AME'S Dental College Hospital and Research Centre, Raichur, Karnataka, India.

Congenital nevi are present in approximately 2-3% of neonates. These lesions are present at birth. They are characterized by pigmented lesions with regular margins, smooth or lobular surfaces and occasionally have long coarse hair. Read More

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January 2011
4 Reads

Focal blue nevus of the eyelid margin (mucocutaneous junction): a report of a unique case with a review of the literature.

Ophthalmic Plast Reconstr Surg 2011 Sep-Oct;27(5):338-42

Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.

Purpose: To describe the first isolated and focal benign blue nevus of the eyelid margin.

Methods: Review of clinical, histopathologic, and immunohistochemical characteristics and relevant literature.

Results: A 93-year-old Caucasian woman with a flat, irregular, and deeply pigmented black growth of the left upper eyelid margin of unknown duration underwent a full-thickness eyelid excisional biopsy. Read More

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November 2011
1 Read

Blue nevus of the tarsus as the predominant component of a combined nevus of the eyelid.

Ophthalmic Plast Reconstr Surg 2011 Jul-Aug;27(4):e94-6

David G Cogan Laboratory of Ophthalmic Pathology, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA.

A 40-year-old man presented with a pigmented lesion of the palpebral conjunctiva and margin of the right lower eyelid. Because of suspicion of melanoma, the lesion was resected. Microscopic examination revealed 2 distinct components: a dominant blue nevus in the tarsus consisting of bland pigmented spindle and epithelioid cells that dissected among the orbicularis muscle fibers and meibomian glands, and a small subepithelial nevomelanocytic component with no overlying junctional activity. Read More

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September 2011
1 Read

Melanocytic nevi of the tarsal conjunctiva: clinicopathologic case series with review of literature.

Ophthalmic Plast Reconstr Surg 2010 Nov-Dec;26(6):438-42

Department of Ophthalmology, New Jersey Medical School, Newark, New Jersey, USA.

Purpose: To describe 4 patients with histopathologically confirmed tarsal conjunctival nevi and to review the literature regarding nevi in this location.

Methods: Clinicopathologic series of 4 cases diagnosed at the New York Eye and Ear Infirmary between January 1990 and April 2009. PubMed was searched for reported cases of tarsal conjunctival nevi. Read More

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March 2011
3 Reads

Pigmented basal cell carcinoma of the eyelid in Hispanics.

Clin Ophthalmol 2008 Sep;2(3):641-3

Department of Oculoplastics, Doheny Eye Institute, Los Angeles, CA, USA.

Background: Pigmented basal cell carcinoma (PBCC) of the eyelid has not been well cited in the literature, and is often overlooked in the differential diagnosis of pigmented eyelid lesions. We aim to describe PBCC of the eyelid in Hispanic patients.

Methods: Retrospective review of patients with eyelid skin cancer who presented to the Department of Dermatology at the Keck School of Medicine of the University of Southern California and the Doheny Eye Institute from January 2002 to November 2005. Read More

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September 2008
2 Reads

Ocular manifestations of long-term mascara use.

Ophthalmic Plast Reconstr Surg 2009 Jul-Aug;25(4):339-41

Albany Medical College, Albany, NY 12159,, USA.

Mascara, a widely used cosmetic, is associated with eye pathology. The authors report 3 cases of eye problems secondary to long-term mascara use. Two patients had multiple pigmented conjunctival lesions; one of these had a history of melanoma of the hand. Read More

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September 2009
1 Read

Detection of canine oral papillomavirus DNA in conjunctival epithelial hyperplastic lesions of three dogs.

Vet Pathol 2009 Jan;46(1):34-8

Animal Pathology, Augsburg, Germany.

Papillomavirus infections are responsible for plaques and papillomas in various locations on the skin and in mucous membranes. The aim of this report was to describe morphologic features of a viral pigmented conjunctival plaque and 2 conjunctival squamous papillomas in 3 dogs, and to investigate these lesions for the presence of papillomavirus DNA by polymerase chain reaction (PCR), DNA sequence analysis, and in situ hydridization (ISH). Histopathology revealed in all neoplasms various degrees of epithelial hyperplasia, acanthosis, and hyperkeratosis with koilocytosis. Read More

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January 2009
2 Reads

New-onset herpes simplex virus keratitis after cataract surgery.

Cornea 2009 Jan;28(1):108-10

Department of Ophthalmology, New York University School of Medicine, NYU Langone Medical Center, New York, NY 10016, USA.

We report the case of a 34-year-old man who had uncomplicated cataract surgery in his left eye. Medical history was significant for atopic dermatitis, requiring oral immunosuppressive medications. Two days after the surgery, the patient presented with pain, photophobia, decreased vision, and a small corneal abrasion. Read More

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January 2009
1 Read

Nevi with site-related atypia: a review of melanocytic nevi with atypical histologic features based on anatomic site.

J Cutan Pathol 2008 Oct;35(10):889-98

Department of Dermatology and Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

A subset of melanocytic nevi share features with melanoma and nevi with architectural disorder but are biologically inert and to date do not appear to portend an increased risk for the development of malignancy. These benign nevi with certain atypical histologic features cluster among specific anatomic sites and are thus designated nevi with site-related atypia. We categorize these lesions into four main groups: acral, genital, special site and conjunctival, based on anatomy and relative prevalence of specific atypical histologic features. Read More

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October 2008
2 Reads

Incidence of melanocytic lesions of the conjunctiva in a review of 10 675 ophthalmic specimens.

Int J Surg Pathol 2010 Feb 8;18(1):60-3. Epub 2008 Jul 8.

Department of Ophthalmology, The McGill University Health Center, Montreal, Quebec, Canada.

During the study period, 10,675 human ophthalmic specimens were received at The Henry C. Witelson Ophthalmic Pathology Laboratory and Registry, McGill University, Montreal, Canada. Of those, 271 were conjunctival lesions (2. Read More

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February 2010
2 Reads

Bilateral anterior uveitis after intense pulsed light therapy for pigmented eyelid lesions.

Dermatol Surg 2008 Sep 12;34(9):1276-9. Epub 2008 Jun 12.

Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.

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September 2008
11 Reads

Treatment of lentigo maligna with imiquimod 5% cream.

J Drugs Dermatol 2007 Oct;6(10):1037-40

North Valley Dermatology Center, Chico, CA 95926, USA.

Lentigo maligna (LM) is an in situ melanoma that occurs in sun-damaged skin on the head and neck of elderly patients. Surgical excision is the treatment of choice for LM. However, surgical options may be limited by the location of LM in cosmetically sensitive areas. Read More

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October 2007
1 Read

Ultrasound biomicroscopy of eyelid eccrine hidrocystoma.

Can J Ophthalmol 2007 Oct;42(5):750-1

Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.

Case Report: A 58-year-old white female noted a lesion on her left lower eyelid, present for 3 months. Examination disclosed a dark-blue, subepithelial, smooth mass along the cilia near the punctum. The lesion did not transmit light and was thought to be a solid mass, such as a deep-blue nevus or melanoma versus a cystic mass with internal debris. Read More

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October 2007
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Use of chemical ablation with trichloroacetic acid to treat eyelid apocrine hidrocystomas in a cat.

J Am Vet Med Assoc 2007 Apr;230(8):1170-3

Graduate Institute of Veterinary Medicine, College of Bioresources and Agriculture, National Taiwan University, Taipei, Taiwan.

Case Description: A 7-year-old Persian cat was evaluated for recurrence of multiple cystic periocular masses. A number of cyst-like lesions had been resected from the left eyelids 18 months earlier, with lesions recurring within 6 months after surgery. The cat had blepharospasm and signs of discomfort following rupture of the largest cyst the day prior to examination. Read More

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April 2007
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