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Sci Rep 2020 05 20;10(1):8305. Epub 2020 May 20.

Office of the Clinical Director, Intramural Research Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.

Purpose: To characterize rheumatological manifestations of GATA2 deficiency.

Methods: Single-center, retrospective review of 157 patients with GATA2 deficiency. Disease course, laboratory results, and imaging findings were extracted. Read More

J Cutan Pathol 2019 Apr 30;46(4):277-279. Epub 2019 Jan 30.

Department of Pathology, University College of Medical Sciences & GTB Hospital (University of Delhi), Delhi, India.

Precalcaneal congenital fibrolipomatous hamartoma (PCFH) is a benign under-reported condition of infancy characterized by the presence of soft nodules on precalcaneal plantar surface of the heel. These lesions are usually bilateral solitary and asymptomatic. We present a 2-month-old infant with solitary skin-colored nodules present on precalcaneal plantar aspect of bilateral heels. Read More

Presse Med 2019 01 7;48(1 Pt 1):88. Epub 2018 Dec 7.

University Hospital of Geneva, department of Dermatology, Geneva, Switzerland.

JAAD Case Rep 2018 Jul 13;4(6):582-583. Epub 2018 Jun 13.

Derma Clinic, Riyadh, Saudi Arabia.

J Am Podiatr Med Assoc 2018 Mar;108(2):178-181

Acrokeratoelastoidosis (AKE) is a rare form of focal acral keratoderma of unknown cause that typically begins during childhood and manifests with multiple, small, hyperkeratotic papules located over the lateral margins of the hands and feet. The purpose of this article is to report a pediatric case of AKE with dermoscopic, sonographic, and histopathologic descriptions, contributing to the awareness of this clinical diagnosis. We describe a 7-year-old girl with nonpainful yellowish papules on the lateral and medial aspects of both feet. Read More

Am J Dermatopathol 2019 06;41(6):463-464

Department of Dermatology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

J Dermatol 2017 Dec 15;44(12):e361-e362. Epub 2017 Aug 15.

Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Indian J Dermatol 2016 Mar-Apr;61(2):234

Department of Cardiology, Faculty of Medicine, University of Baskent, Ankara, Turkey.

Piezogenic pedal papules (PPP) are herniations of subcutaneous adipose tissue into the dermis. PPP are skin-colored to yellowish papules and nodules on lateral surfaces of feet that typically become apparent when the patient stands flat on his/her feet. Some connective tissue diseases and syndromes have been reported in association with PPP. Read More

An Bras Dermatol 2015 Nov-Dec;90(6):928-9

Universidade Federal da Bahia, Salvador, BA, Brazil.

Actas Dermosifiliogr 2015 Sep 20;106(7):591-3. Epub 2015 Feb 20.

Servicio de Dermatología, Hospital Universitario La Paz, Madrid, España.

Indian Dermatol Online J 2013 Oct;4(4):369-71

Department of Pathology, Yuzuncu Yil University, Faculty of Medicine, Van, Turkey.

J Pediatr 2013 Dec 5;163(6):1788. Epub 2013 Sep 5.

Departments of Dermatology, Venereology, and Allergology, University Hospital Würzburg, Würzburg, Germany.

Acta Dermatovenerol Croat 2013 ;21(2):118-22

Department of Dermatology and Venereology, Hospital São João, Alameda Professor Hernâni Monteiro, 4200-319 Porto, Portugal.

Easy bruising in children represents a diagnostic conundrum. Although trauma (accidental or not) and bleeding disturbances are the most common causes, other rarer etiologies should be considered in differential diagnosis. When a 4-year-old male patient presented with a history of bruising and hematomas after slight injuries, coagulopathy and physical abuse were suspected. Read More

CMAJ 2013 Dec 24;185(18):E847. Epub 2013 Jun 24.

Am J Dermatopathol 2012 Dec;34(8):e111-3

Department of Dermatology, The Armed Forces Hongcheon Hospital, Hongcheon, Korea.

Piezogenic papules are lesions that occur on the feet and wrists because of the herniation of fat through the dermis. These papules can be painful or completely asymptomatic. Poor compartmentalization of fat occurs because of thinner than normal fibrous trabeculae and contributes to the formation of piezogenic papules. Read More

Sports Med 2011 Sep;41(9):709-19

Department of Dermatology, Columbia University Medical Center, New York, NY 10032, USA.

Figure skaters, ice-hockey players and speed skaters experience a range of dermatologic conditions and tissue-related injuries on account of mechanical trauma, infectious pathogens, inflammatory processes and environmental factors related to these competitive pursuits. Sports medicine practitioners, family physicians, dermatologists and coaches should be familiar with these skin conditions to ensure timely and accurate diagnosis and management of affected athletes. This review is Part I of a subsequent companion review and provides a comprehensive review of mechanical dermatoses experienced by ice-skating athletes, including skater's nodules and its variants, pump bumps, piezogenic pedal papules, talon noir, skate/lace bite, friction bullae, corns and calluses, onychocryptosis, skater's toe and skate blade-induced lacerations. Read More

Ned Tijdschr Geneeskd 2011 ;155(29):A2576

Slotervaartziekenhuis, afd. Dermatologie, Amsterdam, the Netherlands.

A 57-year-old woman came to the dermatologist because of 'strange bumps' on her feet. The bumps were not painful. On physical examination bumps were seen on the medial parts of her left foot, near the sole. Read More

J Dtsch Dermatol Ges 2010 Jun;8(6):474

J Dtsch Dermatol Ges 2010 Jan;8(1):61-2

Klinik für Dermatologie, Venerologie und Allergologie, Universität Leipzig A.ö.R., Leipzig.

Clin Exp Dermatol 2009 Oct 18;34(7):e325-6. Epub 2009 May 18.

Ned Tijdschr Geneeskd 2008 Jul;152(28):1570

Meander Medisch Centrum, locatie Elisabeth, afd. Dermatologie, Amersfoort.

A 54-year-old woman had piezogenic pedal papules. They became apparent when she was standing, and disappeared when the weight was taken off the foot. Read More

JAAPA 2007 Jul;20(7):15

University of Oklahoma, Physician Assistant Program, Oklahoma City, USA.

Indian J Dermatol Venereol Leprol 2002 Mar-Apr;68(2):107-8

Department of Dermatology, J.N. Medical College, A.M.U., Aligarh, India.

A 14-year-old female with rheumatic heart disease presented with multiple painless, non-itchy papules on her heel. Painless papules consisted of normal fat tissues. Read More

Clin J Sport Med 2006 Jan;16(1):81-3

Department of Dermatology, University of Cincinnati, University Hospital, Cincinnati, OH 45267, USA.

J Eur Acad Dermatol Venereol 2005 Jan;19(1):136-7

Cutis 2004 May;73(5):339-40, 346

Department of Family Practice and Community Medicine, University of Pennsylvania, Philadelphia 19104-4283, USA.

For more than 3 decades, piezogenic pedal papules have been described in the literature. While many individuals with these papules are asymptomatic, patients with trauma or connective tissue diseases can experience pain. In our case study, we describe a unique, nonsurgical approach that abates the pain of painful piezogenic pedal papule (PPPP). Read More

Skinmed 2003 Jan-Feb;2(1):34-40

The Department of Dermatology, Tulane University School of Medicine, 1430 Tulane Avenue TB36, New Orleans, LA 70112, USA.

Various means of skin injury in athletes are examined, supplementing those discussed in Cutaneous Manifestations of Disease Part 1 (November/ December). Skin injury due to mechanical means such as corns, calluses, talon noir (calcaneal petechiae), tennis toe, joggers nipples, and piezogenic pedal papules will be discussed followed by a thorough discussion of environmental means of skin injury. There are a variety of ways that the environment may affect athletes both during competition and years after the competition is finished. Read More

Br J Dermatol 1997 Apr;136(4):628-30

Dermatology Department, West Suffolk Hospital, Bury St Edmunds, Suffolk, U.K.

We report the case of a woman who had pain in both heels which was exacerbated by long periods of exercise. On examination, there were small flesh-coloured papules which appeared over the medial and lateral aspects of the heels only on weight bearing. Coincidentally, she was noted to have larger flesh-coloured papules over the anterior surface of the shins. Read More

Cutis 1996 Apr;57(4):260-2

Division of Dermatology, Saint Louis University Health Sciences Center, Missouri, USA.

Piezogenic pedal papules are small, occasionally painful, fat herniations that become apparent when weight is placed on the heel. Although the cause is unknown, hereditary factors may play a role. This is the second report of two family members with this condition. Read More