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Cureus 2018 Apr 2;10(4):e2404. Epub 2018 Apr 2.

Department of Physiology and Pathophysiology, Division of Pathophysiology, Medical University - Varna "Prof. Dr. Paraskev Stoyanov", Varna, BGR.

Pathophysiology is a medical science whose subject is the change in regulatory mechanisms related to the onset, development, and outcome of diseases. The first lectures on pathophysiology were held in 1790 at the University of Erfurt, Germany, by Professor Augustus Hecker, who in 1791 also published the first work on the discipline - "Grundriss der Physiologia pathologica" in 770 pages. The teaching of pathophysiology as an independent discipline was introduced by academician Viktor Pashutin at the University of Kazan, Russia in 1874. Read More

Physiol Plant 2018 Jun 1. Epub 2018 Jun 1.

Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Department of Physiology and Cell Biology, Corrensstrasse 3 06466 Gatersleben, Germany.

This special issue of Physiologia Plantarum has been prepared to publish some of the highlights presented at the XVIII International Plant Nutrition Colloquium (IPNC), which took place during 19-24 August, 2017 in Copenhagen, Denmark. The meeting was organized by University of Copenhagen. Close to 600 participants from more than 50 different countries participated. Read More

Early Sci Med 2014 ;19(1):1-27

Johannes Kepler (1571-1630) makes extensive use of souls and spiritus in his natural philosophy. Recent studies have highlighted their importance in his accounts of celestial generation and astrology. In this study, I would like to address two pressing issues. Read More

Plant Signal Behav 2008 Jan;3(1):74-5

School of Plant Science; University of Tasmania; Hobart; Tasmania, Australia.

The role of hormones in mediating tropic responses has been a central question in plant biology. Another key issue concerns how interactions between hormones regulate plant responses. In the September 2007 issue of Physiologia Plantarum, we published a paper relevant to both these questions. Read More

Plant Signal Behav 2007 Sep;2(5):365-7

Norwegian University of Life Sciences; Aas, Norway.

It was known that application of glycine betaine (GB) to plants could improve tolerance to stress caused by chilling, frost, salt, drought and high light intensities, and that this effect was accompanied by gene expression changes, but whether the gene expression changes were implicated in GB's effect and which genes were involved has been unclear. In the fourth issue of Physiologia Plantarum, we identified genes upregulated by GB that are involved in reactive oxygen species (ROS) metabolism and membrane trafficking processes. Direct evidence was provided for a role for a membrane trafficking protein (RabA4c) in GB's effect on ROS accumulation during chilling. Read More

Physiol Plant 2004 Jan;120(1):1-3

Lehrstuhl für Biochemie und Physiologie der Pflanzen, Universität Bielefeld, D-33501 Bielefeld, Germany Lehrstuhl für Pflanzenphysiologie, Universität Osnabrück, D-49069 Osnabrück, Germany.

The redox-state is a critical determinate of cell function, and any major imbalances can cause severe damage or death. The cellular redox status therefore needs to be sensed and modulated before such imbalances occur. Various redox-active components are involved in these processes, including thioredoxins, glutaredoxins and other thiol/disulphide-containing proteins. Read More

Physiol Plant 2004 Mar;120(3):386-394

Dipartimento di Biotecnologie e Bioscienze, Universita di Milano-Bicocca, Piazza della Scienza, 20126 Milano, Italy.

Fusicoccin (FC) is a well known toxin acting as a 14-3-3 protein-mediated activator of the plasma membrane H(+)-ATPase and the biochemical and physiological changes induced in the cell by this toxin have, up to now, been ascribed to the increased rate of proton extrusion by this pump leading to external acidification and cell hyperpolarization. In a recent work (Malerba M et al. 2003, Physiologia Plantarum, 119: 480-488) it was shown that, besides the previously well studied changes, FC induces a large stimulation of H(2)O(2) production, an activation of alternative respiration and a leakage of cytochrome c from mitochondria. Read More

Carbohydr Res 2003 May;338(11):1197-208

Complex Carbohydrate Research Center and Department of Biochemistry and Molecular Biology, University of Georgia, 220 Riverbend Road, Athens, GA 30602-4712, USA.

The xyloglucan secreted by suspension-cultured tomato (Lycopersicon esculentum) cells was structurally characterized by analysis of the oligosaccharides generated by treating the polysaccharide with a xyloglucan-specific endoglucanase (XEG). These oligosaccharide subunits were chemically reduced to form the corresponding oligoglycosyl alditols, which were isolated by high-performance liquid chromatography (HPLC). Thirteen of the oligoglycosyl alditols were structurally characterized by a combination of matrix-assisted laser-desorption ionization mass spectrometry and two-dimensional nuclear magnetic resonance (NMR) spectroscopy. Read More

Ann Bot 2002 Nov;90(5):607-12

Department of Vegetable Crops, Institute of Field and Garden Crops, A.R.O., The Volcani Center, Bet Dagan, 50250 Israel.

The processes of pollen grain development and germination depend on the uptake and metabolism of pollen sugars. In pepper (Capsicum annuum L.), initial sugar metabolism includes sucrose hydrolysis by invertase and subsequent phosphorylation of glucose and fructose by hexose kinases. Read More

Arch Bronconeumol 2002 May;38(5):201-3

Cesk Fysiol 1996 Mar;45(1):47-9

Fyziologický ústav AV CR, Praha.

Two physiological journals were founded in Czechoslovakia in 1952, namely Ceskoslovenská fyziologie and an international version which was then named Cechoslovackaja fiziologija, later renamed Physiologia Bohemoslovaca. The first three volumes of the latter journal were published exclusively in Russian with German summaries. It was not until 1956 that most reports began to be published in English, with Russian summaries. Read More

Rev Laryngol Otol Rhinol (Bord) 1993 ;114(4):305-10

CHU Timone, Département O.R.L., Marseille, France.

The purpose of the multiparametric analysis of the vocal phenomenon is to evidence the instability of the signal in amplitude and in frequency, together with the aerodynamic phenomena related to the glottic air leakage. Statistical analysis has made it possible to establish a correlation between the data of the apparatus, as from 9 variables, and the clinical classification. The main diagnostic categories are relatively close, evidencing the various biomechanical anomalies of the laryngeal vibrator. Read More

Patol Fiziol Eksp Ter 1991 (6):1-7

Pathophysiology began from general pathology due to a necessity of experimental analysis of pathological processes. Its origins date back to the works of Magenndie and Claude Bernard who introduced the concept of "experimental pathology". It is noteworthy that the founder of cellular pathology, Rudolph Virchow, emphasized the crucial importance of regulation disturbance for physiological processes as an essential mechanism of disease pathogenesis and used the term "pathological physiology". Read More

Janus 1978 ;65(4):283-96

Ned Tijdschr Geneeskd 1972 Jul;116(27):1124-9

Edinb Med Surg J 1834 Oct;42(121):383-415