2,087,241 results match your criteria Physical & Occupational Therapy in Geriatrics [Journal]


Comparison of overall survival and quality of life between patients undergoing anal reconstruction and patients undergoing traditional lower abdominal stoma after radical resection.

Clin Transl Oncol 2019 Apr 20. Epub 2019 Apr 20.

The Department of General Surgery, Second Hospital of Lanzhou University, No. 82, Cuiying Gate, Chengguan District, Lanzhou, 730030, Gansu, China.

Background: Miles procedure is often necessary for patients with low rectal carcinoma. However, this operation often affects the quality of life of patients, to evaluate the advantages of improved operation (anal reconstruction), the quality of life and survival between patients undergoing anal reconstruction and patients undergoing traditional lower abdominal stoma after radical resection were analyzed.

Methods: The clinical data of 43 patients with low situated rectal carcinoma were retrospectively analyzed. Read More

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http://dx.doi.org/10.1007/s12094-019-02106-xDOI Listing

Body Image, Assimilation, and Weight of Immigrant Adolescents in the United States: A Person-Centered Analysis.

J Immigr Minor Health 2019 Apr 20. Epub 2019 Apr 20.

Department of Psychology, Suffolk University, 73 Tremont Street, Boston, MA, 02108, USA.

Adolescence is a critical developmental period as youth explore their body image and work to establish an identity. The stress of identity and body image development can be exacerbated by acculturative stress faced by immigrant adolescents. Using a person-centered analysis, we investigated immigrant adolescents' (n = 57) profiles based on assimilation to the United States (US), weight, and body image dissatisfaction. Read More

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http://dx.doi.org/10.1007/s10903-019-00892-8DOI Listing

Non-communicable disease prevention in Mexico: policies, programs and regulations.

Health Promot Int 2019 Apr 21. Epub 2019 Apr 21.

University of Arizona, Mel and Enid Zuckerman College of Public Health, 1296 N. Martin, Tucson, AZ 85724, USA.

Non-communicable diseases (NCD), such as diabetes and cardiovascular disease, have become a leading cause of the death in Mexico. The federal government has addressed this issue through developing NCD prevention plans, regulations and policies (PRPs) that seek to address social and environmental factors, which was led by the National Institute of Public Health and Ministry of Health in concert with various non-governmental organizations. This review aims to synthesize and summarize national NCD prevention PRPs addressing social and environmental factors passed from 2010 to 2016, and to assess the extent to which these efforts successfully addressed factors contributing to the epidemic. Read More

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http://dx.doi.org/10.1093/heapro/daz029DOI Listing

A theory-based, task-oriented, outdoor walking programme for older adults with difficulty walking outdoors: protocol for the Getting Older Adults Outdoors (GO-OUT) randomised controlled trial.

BMJ Open 2019 Apr 20;9(4):e029393. Epub 2019 Apr 20.

College of Kinesiology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.

Introduction: A theory-based, task-oriented, community walking programme can increase outdoor walking activity among older adults to optimise functional independence, social participation and well-being. The study objective is to determine if there is a difference in the change in outdoor walking activity from baseline to 10 weeks, 5.5 months and 12 months after receiving a 1-day interactive workshop and outdoor walking programme (Getting Older Adults Outdoors (GO-OUT)) compared with the workshop and weekly reminders (WR) in older adults with difficulty walking outdoors. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2019-02939
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http://dx.doi.org/10.1136/bmjopen-2019-029393DOI Listing
April 2019
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Protocol for the Gut Bugs Trial: a randomised double-blind placebo-controlled trial of gut microbiome transfer for the treatment of obesity in adolescents.

BMJ Open 2019 Apr 20;9(4):e026174. Epub 2019 Apr 20.

Liggins Institute, University of Auckland, Auckland, New Zealand.

Introduction: Animal studies showed that germ-free mice inoculated with normal mouse gut bacteria developed obesity, insulin resistance and higher triglyceride levels, despite similar food intake. In humans, an association has been found between obesity and gut microbiome dysbiosis. However, gut microbiome transfer has not been evaluated for the treatment of human obesity. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02617
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http://dx.doi.org/10.1136/bmjopen-2018-026174DOI Listing
April 2019
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Does the 'Chinese New Year effect' exist? Hospital mortality in patients admitted to internal medicine departments during official consecutive holidays: a nationwide population-based cohort study.

BMJ Open 2019 Apr 20;9(4):e025762. Epub 2019 Apr 20.

Department of Family Medicine, Buddhist Tzu Chi General Hospital, Hualien, Taiwan.

Objective: Our study aimed to compare the mortality risk among patients admitted to internal medicine departments during official consecutive holidays (using Chinese New Year holidays as an indicator) with that of weekend and weekday admissions.

Design: Nationwide population-based cohort study.

Setting: Taiwan's National Health Insurance Research Database. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025762DOI Listing

Patient expectations of a new treatment for eating disorders combining guided physical exercise and dietary therapy: an interview study of women participating in a randomised controlled trial at the Norwegian School of Sport Sciences.

BMJ Open 2019 Apr 20;9(4):e025344. Epub 2019 Apr 20.

Department of Sports Medicine, Norwegian School of Sport Sciences, Norway, Europe.

Objectives: To study the expectations women with bulimia nervosa (BN) or binge eating disorder (BED) had to a new treatment programme based on guided physical exercise and dietary therapy.

Design And Participants: Semistructured interviews were conducted with six women with BN and four women with BED following a group-based therapy programme. Transcribed interviews were analysed using a text-condensing analytic approach. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025344DOI Listing

The FOOTPATH study: protocol for a multicentre, participant- and assessor-blind, parallel group randomised clinical trial of foot orthoses for patellofemoral osteoarthritis.

BMJ Open 2019 Apr 20;9(4):e025315. Epub 2019 Apr 20.

La Trobe Sport and Exercise Medicine Research Centre, College of Science, Health and Engineering, La Trobe University, Melbourne, Victoria, Australia.

Introduction: Patellofemoral (PF) osteoarthritis (OA) is a common and burdensome subgroup of knee OA, with very little evidence for effective treatments. Prefabricated foot orthoses are an affordable and accessible intervention that have been shown to reduce PF pain in younger adults. Similarities between PF pain and PFOA, as well as our pilot work, suggest that foot orthoses may also be an effective intervention for PFOA. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02531
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http://dx.doi.org/10.1136/bmjopen-2018-025315DOI Listing
April 2019
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Socioeconomic trajectories of body mass index and waist circumference: results from the English Longitudinal Study of Ageing.

BMJ Open 2019 Apr 20;9(4):e025309. Epub 2019 Apr 20.

Epidemiology and Public Health, University College London, London, UK.

Objectives: To explore age trajectories of body mass index (BMI) and waist circumference (WC) and to examine whether these trajectories varied by wealth.

Design: Nationally representative prospective cohort study.

Setting: Observational study of people living in England. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-025309DOI Listing

Diet quality in relation to healthy ageing: the Israeli Longitudinal Study on Aging (ILSA)-a study protocol.

BMJ Open 2019 Apr 20;9(4):e024673. Epub 2019 Apr 20.

Department of Epidemiology and Preventive Medicine, Tel Aviv University, Tel Aviv, Israel.

Introduction: Population ageing is accelerating rapidly in Israel as well as worldwide, necessitating adaptation of the healthcare system and consideration of new approaches that serve the specific needs of older adults. In addition to cognitive function, frailty is one of the most challenging expressions of physical and mental ageing, a multidimensional syndrome of increased vulnerability. Several studies have shown that low intake of certain micronutrients and protein is associated with higher risk of frailty and cognitive impairment. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024673DOI Listing

Identification of earlier predictors of pregnancy complications through wearable technologies in a Brazilian multicentre cohort: Maternal Actigraphy Exploratory Study I (MAES-I) study protocol.

BMJ Open 2019 Apr 20;9(4):e023101. Epub 2019 Apr 20.

Social Medicine, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Ribeirao Preto, Brazil.

Introduction: Non-invasive tools capable of identifying predictors of maternal complications would be a step forward for improving maternal and perinatal health. There is an association between modification in physical activity (PA) and sleep-wake patterns and the occurrence of inflammatory, metabolic, pathological conditions related to chronic diseases. The actigraphy device is validated to estimate PA and sleep-wake patterns among pregnant women. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023101DOI Listing

Repatriation for diseases or non-battle injuries (DNBI): long-term impact on quality of life.

J R Army Med Corps 2019 Apr 20. Epub 2019 Apr 20.

Defense Healthcare Organization, Ministry of Defense, Utrecht, the Netherlands.

Introduction: Throughout history, diseases and non-battle injuries (DNBI) have threatened deployed forces more than battlefield injuries. During the Dutch involvement in Afghanistan, the amount of DNBI that needed medical evacuation out of theatre (60%) exceeded the number of battle injuries (40%). The aim of this study is to explore the long-term quality of life (QoL) of Dutch service members that acquired a DNBI, warranting repatriation during their deployment to Afghanistan between 2003 and 2014. Read More

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http://dx.doi.org/10.1136/jramc-2019-001194DOI Listing

Identification of piecewise linear dynamical systems using physically-interpretable neural-fuzzy networks: Methods and applications to origami structures.

Neural Netw 2019 Apr 8;116:74-87. Epub 2019 Apr 8.

Institute of AI and Robotics, Fudan University, Shanghai 200433, China. Electronic address:

Self-locking origami structures are characterized by their piecewise linear constitutive relations between force and deformation, which, in practice, are always completely opaque and unmeasurable: the number of piecewise segments, the positions of non-smooth points, and the linear parameters of each segment are unknown a priori. However, acquiring this information is of fundamental importance for understanding the origami structure's dynamic folding process and predicting its dynamic behaviors. This, therefore, arouses our interest in adopting a dynamical identification process to determine the model and to estimate the parameters. Read More

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http://dx.doi.org/10.1016/j.neunet.2019.04.007DOI Listing

Electronic properties and vibrational spectra of (NH)M″(SO)·6HO (M = Ni, Cu) Tutton's salt: DFT and experimental study.

Spectrochim Acta A Mol Biomol Spectrosc 2019 Apr 15;218:281-292. Epub 2019 Apr 15.

National System of Laboratories in Nanotechnologies (SisNANO), Department of Physics, Federal University of Viçosa, Viçosa 36570-000, MG, Brazil.

The complex crystals of the family of the Tutton's salt have been investigated through the numerous experimental and theoretical studies to understand their physical properties and their potential technological applications. In spite of the more than 60 years of research, there are very few studies about the electronic properties of Tutton's salt. In our present work, we have calculated the stability, electronic properties and the first theoretical study of band structure of the three different crystals of the Tutton's salt, ammonium nickel sulfate hexahydrate ((NH)Ni(SO)·6HO), ammonium nickel-copper sulfate hexahydrate ((NH)NiCu(SO)·6HO) and ammonium copper sulfate hexahydrate ((NH)Ni(SO)·6HO) with the help of periodic ab-initio calculations based on density functional theory (DFT). Read More

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http://dx.doi.org/10.1016/j.saa.2019.04.023DOI Listing

Exercise-induced anti-inflammatory effects in overweight/obese women with polycystic ovary syndrome.

Cytokine 2019 Apr 18;120:66-70. Epub 2019 Apr 18.

Applied Physiology & Nutrition Research Group, Laboratory of Assessment and Conditioning in Rheumatology, School of Physical Education and Sport, School of Medicine, University of São Paulo, Brazil; Rheumatology Division, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, Brazil. Electronic address:

Polycystic ovary syndrome (PCOS) is characterized by exacerbated inflammation, which is implicated in cardiometabolic dysfunction. This study aimed to examine the potential effects of acute exercise on inflammatory responses in obese/overweight PCOS women and their controls. Participants underwent a single bout of moderate-intensity aerobic exercise (30 min at ∼65% of VO). Read More

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http://dx.doi.org/10.1016/j.cyto.2019.04.006DOI Listing

Direct and facile synthesis of highly porous low cost carbon from potassium-rich wine stone and their application for high-performance removal.

J Hazard Mater 2019 Apr 13;374:238-247. Epub 2019 Apr 13.

Fırat University, Faculty of Engineering, Department of Chemical Engineering, 23279 Elazığ, Turkey. Electronic address:

Alkaline potassium compounds such as KCO and KOH are chemical activators used to produce activated carbons (ACs). The substance, known as wine stone or cream of tartar and formed in wine fermentation tanks during wine production from grape juice concentrates, consists of potassium hydrogen tartrate (KHCHO). Highly porous carbons with various textural characteristics were obtained from organic wine stone subjected to simple heat-treatment. Read More

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http://dx.doi.org/10.1016/j.jhazmat.2019.04.042DOI Listing

3D type I collagen environment leads up to a reassessment of the classification of human macrophage polarizations.

Biomaterials 2019 Apr 13;208:98-109. Epub 2019 Apr 13.

Team Mechanobiology, Immunity and Cancer, Institute for Advanced Biosciences, Inserm U1209, CNRS UMR5309, La Tronche, France; Grenoble Alpes University, Grenoble, France; Research Department, University Hospital of Alpes, Grenoble, France. Electronic address:

Macrophages have multiple roles in development, tissue homeostasis and repair and present a high degree of phenotypic plasticity embodied in the concept of polarization. One goal of macrophage biology field is to characterize these polarizations at the molecular level. To achieve this task, it is necessary to integrate how physical environment signals are interpreted by macrophages under immune stimulation. Read More

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http://dx.doi.org/10.1016/j.biomaterials.2019.04.018DOI Listing

Influence of the welan gum biopolymer concentration on the rheological properties, droplet size distribution and physical stability of thyme oil/W emulsions.

Int J Biol Macromol 2019 Apr 18. Epub 2019 Apr 18.

Departamento de Ingeniería Química, Facultad de Química, Universidad de Sevilla, C/ Profesor García González, s/n, 41012 Sevilla, Spain. Electronic address:

The objective of this work is to obtain a stable and natural antimicrobial delivery system. Thus, the effect of the addition of a natural polysaccharide such as welan gum on the linear viscoelastic properties, flow behaviour, droplet size distribution and physical stability of thyme oil/W emulsions formulated with a wheat-derived surfactant was studied. All emulsions obtained show submicron diameters regardless of the concentration of welan. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.137DOI Listing

Characterization of a high-performance edible film based on Salep mucilage functionalized with pennyroyal (Mentha pulegium).

Int J Biol Macromol 2019 Apr 18. Epub 2019 Apr 18.

Transfer Phenomena Laboratory (TPL), Department of Food Science, Technology and Engineering, Faculty of Agricultural Engineering and Technology, University of Tehran, Iran.

Salep mucilage was extracted from salep tubers and used to produce edible films containing pennyroyal extracts (PER) (0, 0.5, 1, and 1.5% v/v) as a new antibacterial/antioxidant edible film, and their physical, mechanical, permeability, thermal, microstructural and antibacterial properties were measured. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2019.04.136DOI Listing

Translating, modifying, and validating the Adult Picky Eating Questionnaire for use in China.

Eat Behav 2019 Apr 13;33:78-84. Epub 2019 Apr 13.

School of Humanities and Social Science, Chinese University of Hong Kong (Shenzhen), Shenzhen, Guangdong, China. Electronic address:

Objective: The aim of this study was to translate, modify, and validate the Adult Picky Eating Questionnaire (APEQ) for use in China.

Methods: Based on standard procedures, the APEQ was translated into Chinese. Four items were added in the final Chinese version of the APEQ (C-APEQ). Read More

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http://dx.doi.org/10.1016/j.eatbeh.2019.04.002DOI Listing

Improving blood pressure control in primary care: The ImPress study.

Int J Nurs Stud 2019 Apr 4;95:28-33. Epub 2019 Apr 4.

Faculty of Health Sciences and Medicine, Bond University, Queensland, Australia.

Background: Hypertension is a preventable risk factor for cardiovascular disease, the leading cause of death globally. When hypertension is present with tobacco smoking, poor nutrition, physical inactivity or excessive alcohol consumption, risk of cardiovascular disease is increased. Given the prolonged engagement and ongoing relationship with patients, general practice nurses are ideally situated to actively engage with patients about optimal blood pressure control and lifestyle risk reduction. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00207489193008
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http://dx.doi.org/10.1016/j.ijnurstu.2019.03.019DOI Listing
April 2019
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Effects of quinones and nitroazoles on free-radical fragmentation of glycerol-1-phosphate and 1,2-dimyristoyl-glycero-3-phosphatidyl-glycerol.

Chem Phys Lipids 2019 Apr 18. Epub 2019 Apr 18.

Department of Chemistry of the Belarusian State University, 4 Nezavisimosti Av., 220030, Minsk, Belarus; Research Institute for Physical and Chemical Problems of the Belarusian State University, 14 Leningradskaya St., 220050, Minsk, Belarus. Electronic address:

Effects of quinones and azoles on the formation of steady-state radiolysis products in aqueous solutions of glycerol-1-phosphate and aqueous dispersions of 1,2-dimyristoyl-glycero-3-phosphatidyl-glycerol has been investigated. The data obtained by LC-MS-ESI and spectrophotometric measurements shows that the compounds having quinoid structures, including the antitumor agent doxorubicin, and azoles having nitro groups effectively inhibit free-radical fragmentation of glycerol-1-phosphate and 1,2-dimyristoyl-glycero-3-phosphatidyl-glycerol, decreasing the radiation-chemical yields of either inorganic phosphate or phosphatidic acid respectively. The observed effects of blocking free-radical processes are believed to be related to the ability of the tested compounds to oxidize α-hydroxyl-containing carbon-centered radicals of starting substrates, which give rise to fragmentation reaction. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00093084193000
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http://dx.doi.org/10.1016/j.chemphyslip.2019.04.008DOI Listing
April 2019
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OVOTESTICULAR DISORDER OF SEX DEVELOPMENT: A RARE CASE OF LATERAL SUBTYPE 45X/46XY KARIOTYPE DIAGNOSED IN ADULTHOOD.

Urology 2019 Apr 18. Epub 2019 Apr 18.

Endocrinology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy; Interdisciplinary Research Center of Autoimmune Diseases, Università del Piemonte Orientale, Novara, Italy.

A 53-year-old male referred to our Centre because of hypergonadotropic hypogonadism detected during urological follow-up for urethral lithiasis. Physical Examination showed short stature, micropenis, ambiguous external genitalia, normal secondary sexual characteristics. Karyotype: 45 × 0/46XY. Read More

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http://dx.doi.org/10.1016/j.urology.2019.04.008DOI Listing

The association between vitamin D status and metabolic syndrome and its components among female teachers residing in Yazd city.

Endocrinol Diabetes Nutr 2019 Apr 17. Epub 2019 Apr 17.

Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran; Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Electronic address:

Background: Studies trying to find the association between vitamin D status and metabolic syndrome (MetS) have led to inconsistent results, and community-based data for individuals living in the Middle East are limited.

Objectives: To find out if MetS and its components are associated with vitamin D status among female teachers residing in Yazd city during winter 2015.

Materials And Methods: A total of 276 female teachers (case group, n=124 and control group, n=152) aged 20-60 years were included. Read More

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http://dx.doi.org/10.1016/j.endinu.2019.02.006DOI Listing

Adverse Childhood Experiences in Mothers with Chronic Pain and Intergenerational Impact on Children.

J Pain 2019 Apr 18. Epub 2019 Apr 18.

Department of Pediatrics, Institute on Development and Disability, Oregon Health & Science University.

Adverse childhood experiences (ACEs; e.g., parental divorce, physical or sexual abuse) are more prevalent in individuals with chronic pain compared to the general population. Read More

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http://dx.doi.org/10.1016/j.jpain.2019.04.004DOI Listing

Frailty trajectories in adult lung transplantation: A cohort study.

J Heart Lung Transplant 2019 Mar 18. Epub 2019 Mar 18.

Departments of Medicine.

Background: Frailty is common in adults with advanced lung disease and is associated with death before and after lung transplantation. We aimed to determine whether frailty changes from before to after the lung transplant.

Methods: In a single-center, prospective cohort study among adults undergoing lung transplantation from 2010 to 2017, we assessed frailty by the Short Physical Performance Battery (SPPB; higher scores reflect less frailty) and Fried Frailty Phenotype (FFP; higher scores reflect greater frailty) before and repeatedly up to 36 months after transplant. Read More

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http://dx.doi.org/10.1016/j.healun.2019.03.006DOI Listing

Phenomenological tissue fracture modeling for an Endoscopic Sinus and Skull Base Surgery training system based on experimental data.

Med Eng Phys 2019 Apr 17. Epub 2019 Apr 17.

School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

The ideal simulator for Endoscopic Sinus and Skull Base Surgery (ESSS) training must be supported by a physical model and provide repetitive behavior in a controlled environment. Development of realistic tissue models is a key part of ESSS virtual reality (VR)-based surgical simulation. Considerable research has been conducted to address haptic or force feedback and propose a phenomenological tissue fracture model for sino-nasal tissue during surgical tool indentation. Read More

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http://dx.doi.org/10.1016/j.medengphy.2019.02.004DOI Listing

[Influence of post-traumatic stress disorder on asthma].

Presse Med 2019 Apr 17. Epub 2019 Apr 17.

Université de Poitiers, centre hospitalier Henri-Laborit, unité de recherche clinique, 86021 Poitiers, France.

Introduction: Exposure to a traumatic event may not only lead to a large variety of mental disorders, such as post-traumatic stress disorder (PTSD) but also respiratory symptoms and/or respiratory diseases, as asthma.

Objectives: Systematic literature review of data on the impact of post-traumatic stress disorder on asthma.

Documentary Sources: Medline, on the period 1980-2018 with the following keywords: "PTSD" or "post-traumatic stress disorder" or "post-traumatic stress disorder" and "asthma", limits "title/abstract"; the selected languages were English or French. Read More

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http://dx.doi.org/10.1016/j.lpm.2019.03.002DOI Listing

Quality of life in patients with multiple sclerosis: A study with patients and caregivers.

Disabil Health J 2019 Mar 28. Epub 2019 Mar 28.

Department of Applied Psychology, School of Psychology, University of Minho, Braga, Portugal. Electronic address:

Background: Multiple Sclerosis (MS) is a chronic disease that affects patients' quality of life and requires long term demanding care.

Objective: The purpose of this study was to examine the relationships between patients and caregivers' variables regarding patients' quality of life, the moderating role of marital satisfaction between patients' psychological morbidity and quality of life, and the contribution of patient and caregiver variables towards patients' quality of life.

Methods: The sample included 100 patients with MS and 72 caregivers. Read More

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http://dx.doi.org/10.1016/j.dhjo.2019.03.007DOI Listing

Long-term follow-up of total shoulder replacement surgery with inset glenoid implants for arthritis with deficient bone.

J Shoulder Elbow Surg 2019 Apr 17. Epub 2019 Apr 17.

Sentara Martha Jefferson Hospital, Charlottesville, VA, USA.

Background: Total shoulder replacement surgery has been a successful treatment for patients with shoulder arthritis. However, long-term results are limited by complications such as glenoid loosening, wear, and instability. Also, glenoid bone deficiency limits available treatment options and outcomes. Read More

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http://dx.doi.org/10.1016/j.jse.2019.01.020DOI Listing

Trends in Energy Drink Consumption Among U.S. Adolescents and Adults, 2003-2016.

Am J Prev Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Health Policy and Management, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.

Introduction: Energy drinks refer to non-alcoholic beverages that contain caffeine, amino acids, herbs, and vitamins. Although energy drinks are marketed to reduce fatigue and improve physical/mental performance, frequent consumption of these beverages has been linked to negative health consequences. The purpose of this study is to provide timely, national estimates of the percentage of energy drink consumers in the U. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07493797193002
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http://dx.doi.org/10.1016/j.amepre.2018.12.007DOI Listing
April 2019
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Ulnar neuropathy at the elbow in 413 Japanese patients: An assessment of pathological elbow lesions and neurological severity.

J Orthop Sci 2019 Apr 17. Epub 2019 Apr 17.

Department of Orthopaedic Surgery, Shinshu University School of Medicine, Japan.

Background: Various pathological elbow lesions are often complicated with ulnar neuropathy at the elbow (UNE), although the precise pathology, incidence, and clinical and neurological features of these lesions have not been identified. We therefore investigated elbow pathology and neurological severity in Japanese patients with UNE.

Methods: The medical records of 457 Japanese UNE patients who were surgically treated among 6 hospitals were retrospectively examined. Read More

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http://dx.doi.org/10.1016/j.jos.2019.03.018DOI Listing

The effect of temperature on the separation of enantiomers with coated and covalently immobilized polysaccharide-based chiral stationary phases.

J Chromatogr A 2019 Apr 13. Epub 2019 Apr 13.

Institute of Physical and Analytical Chemistry, School of Exact and Natural Sciences, Tbilisi State University, Chavchavadze Ave 3, 0179, Tbilisi, Georgia. Electronic address:

This article describes our attempt to re-visit the role of temperature in the separation of enantiomers with polysaccharide-based chiral columns in high-performance liquid chromatography (HPLC). Rarely observed increased retention and separation factors with increasing temperature, as well as temperature dependent reversal of enantiomer elution order are reported for several arylpropionic acid derivatives. Chiral columns with coated and covalently immobilized chiral selectors were compared from the viewpoint of effect of temperature on analyte retention, enantiomer separation and enantiomer elution order. Read More

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http://dx.doi.org/10.1016/j.chroma.2019.04.024DOI Listing

Diagnosis of pain in the right iliac fossa. A new diagnostic score based on Decision-Tree and Artificial Neural Network Methods.

Cir Esp 2019 Apr 17. Epub 2019 Apr 17.

Departamento de Cirugía, Hospital Universitario Arnau de Vilanova, Universidad de Lérida, Lérida, España.

Introduction: Pain in the right iliac fossa (RIF) continues to pose diagnostic challenges. The objective of this study is the development of a RIF pain diagnosis model based on classification trees of type CHAID (Chi-Square Automatic Interaction Detection) and on an artificial neural network (ANN).

Methods: Prospective study of 252 patients who visited the hospital due to RIF pain. Read More

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http://dx.doi.org/10.1016/j.ciresp.2019.02.006DOI Listing

Electrical stimulation induces direct reprogramming of human dermal fibroblasts into hyaline chondrogenic cells.

Biochem Biophys Res Commun 2019 Apr 17. Epub 2019 Apr 17.

Department of Physical Therapy and Rehabilitation, College of Health Science, Eulji University, Seongnam, Republic of Korea. Electronic address:

The repair of articular cartilage needs a sufficient number of chondrocytes to replace the defect tissue. Direct reprogramming of fibroblasts into chondrocytes can provide a sufficient number of chondrocytes because fibroblasts can be expanded efficiently. Herein, we demonstrate for the first time that electrical stimulation can drive direct reprogramming of human dermal fibroblasts (HDFs) into hyaline chondrogenic cells. Read More

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http://dx.doi.org/10.1016/j.bbrc.2019.04.027DOI Listing

The Oligomerization Landscape of Histones.

Biophys J 2019 Apr 17. Epub 2019 Apr 17.

Biophysics Program, Institute for Physical Science and Technology, University of Maryland, College Park, Maryland; Chemical Physics Program, Institute for Physical Science and Technology; Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland. Electronic address:

In eukaryotes, DNA is packaged within nucleosomes. The DNA of each nucleosome is typically centered around an octameric histone protein core: one central tetramer plus two separate dimers. Studying the assembly mechanisms of histones is essential for understanding the dynamics of entire nucleosomes and higher-order DNA packaging. Read More

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http://dx.doi.org/10.1016/j.bpj.2019.03.021DOI Listing

Towards optimal stopping in radiation therapy.

Radiother Oncol 2019 May 6;134:96-100. Epub 2019 Feb 6.

Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, USA. Electronic address:

A typical fractionated radiotherapy (RT) course is a long and arduous process, demanding significant financial, physical, and mental commitments from patients. Each additional session of RT significantly increases the physical and psychological burden on patients and leads to higher radiation exposure in organs-at-risk (OAR), while, in some cases, the therapeutic benefits might not be high enough to justify the risks. Today, through technological advancements in molecular biology, imaging, and genetics more information is gathered about individual patient response before, during, and after the treatment. Read More

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http://dx.doi.org/10.1016/j.radonc.2019.01.010DOI Listing

Feasibility of Dixon magnetic resonance imaging to quantify effects of physical training on muscle composition-A pilot study in young and healthy men.

Eur J Radiol 2019 May 26;114:160-166. Epub 2019 Mar 26.

Institute of Medical Physics, Friedrich-Alexander University Erlangen-Nuremberg (FAU), Henkestr. 91, 91052 Erlangen, Germany; Department of Medicine 3, Friedrich-Alexander University Erlangen-Nuremberg (FAU) and University Hospital Erlangen, Ulmenweg 18, Erlangen, Germany. Electronic address:

Changes in muscle-fat-composition affect physical performance and muscular function, like strength and power. The purpose of the present study was to investigate whether changes in soft tissue composition of the thigh and changes in muscle size and composition resulting from physical training were detectable with Dixon magnetic resonance imaging (MRI). A young and healthy subject population (n = 21, 29 ± 5 years) was split into a strength training (G_t, 11 subjects) and a control group (G_c, 10 subjects). Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.019DOI Listing

An ultrasensitive electrochemical sensor for 17β-estradiol using split aptamers.

Anal Chim Acta 2019 Aug 18;1065:107-112. Epub 2019 Mar 18.

Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran; Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

Herein, a simple electrochemical sensor is proposed for 17β-estradiol (E2) determination. In this sensing platform, split DNA aptamers for E2 were applied as recognizing agents. In the presence of E2, split aptamers are bound to E2 and establish split1-E2-split2 complex as a bridge on the surface of electrode. Read More

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http://dx.doi.org/10.1016/j.aca.2019.02.062DOI Listing

Work-up for Fever During Neutropenia for Both the Stem Cell Transplant Recipient and the Hematologic Malignancy Patient.

Infect Dis Clin North Am 2019 Jun;33(2):381-397

Division of Infectious Diseases, Vanderbilt University Medical Center, A2200 MCN, 1161 21st Avenue South, Nashville, TN 37232-2605, USA. Electronic address:

Fever is a common complication in patients with underlying neutropenia and is associated with significant mortality in neutropenic patients with acute myelogenous leukemia or hematopoietic cell transplant. Fever may be the only sign of infection and requires further clinical assessment, including a history, a physical examination, and additional laboratory and radiographic testing. National and international guidelines recommend initiation of empiric antimicrobial therapy in patients with fever during neutropenia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08915520193000
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http://dx.doi.org/10.1016/j.idc.2019.02.003DOI Listing
June 2019
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Assessing the performance of trajectory surface hopping methods: Ultrafast internal conversion in pyrazine.

J Chem Phys 2019 Apr;150(15):154119

Department of Chemistry, Technical University of Munich, Lichtenbergstr. 4, 85747 Garching, Germany.

Trajectory surface hopping (TSH) methods have been widely used to study photoinduced nonadiabatic processes. In the present study, nonadiabatic dynamics simulations with the widely used Tully's fewest switches surface hopping (FSSH) algorithm and a Landau-Zener-type TSH (LZSH) algorithm have been performed for the internal conversion dynamics of pyrazine. The accuracy of the two TSH algorithms has been critically evaluated by a direct comparison with exact quantum dynamics calculations for a model of pyrazine. Read More

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http://dx.doi.org/10.1063/1.5084961DOI Listing

Effect of iron oxide nanoparticles on fibrin gel formation and its fractal dimension.

J Chem Phys 2019 Apr;150(15):155103

P.N. Lebedev Physical Institute of the Russian Academy of Sciences, 53 Leninskii Prospekt, Moscow 119991, Russia.

In this paper, we studied the influence of nonmagnetic iron oxide nanoparticles on fibrin gel formation and its structure using dynamic light scattering. The surface of nanoparticles produced by a new method in acoustoplasma discharge with cavitation has specific morphology and accelerates the rate of fibrin gel formation, i.e. Read More

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http://dx.doi.org/10.1063/1.5086528DOI Listing

Optimal basis sets for CBS extrapolation of the correlation energy: oVxZ and oV(x+d)Z.

J Chem Phys 2019 Apr;150(15):154106

Departamento de Física, Universidade Federal do Espírito Santo, Vitória 29075-910, Brazil.

We seek correlation consistent double- and triple-zeta basis sets that perform optimally for extrapolating the correlation energy to the one-electron complete basis set limit. Since the methods used are approximate, the novel basis sets become method specific in the sense of performing best for the chosen level of theory. Such basis sets are also shown to perform accurately for tensorial properties and do not significantly alter the Hartree-Fock energy. Read More

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http://dx.doi.org/10.1063/1.5080512DOI Listing

ZMP-SAPT: DFT-SAPT using ab initio densities.

J Chem Phys 2019 Apr;150(15):154101

Faculty of Chemistry, University of Duisburg-Essen, Universitätsstraße 5, 45117 Essen, Germany.

Symmetry Adapted Perturbation Theory (SAPT) has become an important tool when predicting and analyzing intermolecular interactions. Unfortunately, Density Functional Theory (DFT)-SAPT, which uses DFT for the underlying monomers, has some arbitrariness concerning the exchange-correlation potential and the exchange-correlation kernel involved. By using ab initio Brueckner Doubles densities and constructing Kohn-Sham orbitals via the Zhao-Morrison-Parr (ZMP) method, we are able to lift the dependence of DFT-SAPT on DFT exchange-correlation potential models in first order. Read More

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http://dx.doi.org/10.1063/1.5087208DOI Listing

Coarse-graining involving virtual sites: Centers of symmetry coarse-graining.

J Chem Phys 2019 Apr;150(15):154103

Department of Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, USA.

Coarse-grained (CG) models allow efficient molecular simulation by reducing the degrees of freedom in the system. To recapitulate important physical properties, including many-body correlations at the CG resolution, an appropriate mapping from the atomistic to CG level is needed. Symmetry exhibited by molecules, especially when aspherical, can be lost upon coarse-graining due to the use of spherically symmetric CG effective potentials. Read More

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http://dx.doi.org/10.1063/1.5067274DOI Listing

Single-Hessian thawed Gaussian approximation.

J Chem Phys 2019 Apr;150(15):154117

Laboratory of Theoretical Physical Chemistry, Institut des Sciences et Ingénierie Chimiques, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.

To alleviate the computational cost associated with on-the-fly ab initio semiclassical calculations of molecular spectra, we propose the single-Hessian thawed Gaussian approximation in which the Hessian of the potential energy at all points along an anharmonic classical trajectory is approximated by a constant matrix. The spectra obtained with this approximation are compared with the exact quantum spectra of a one-dimensional Morse potential and with the experimental spectra of ammonia and quinquethiophene. In all cases, the single-Hessian version performs almost as well as the much more expensive on-the-fly ab initio thawed Gaussian approximation and significantly better than the global harmonic schemes. Read More

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http://dx.doi.org/10.1063/1.5090122DOI Listing

Unsupervised machine learning in atomistic simulations, between predictions and understanding.

Authors:
Michele Ceriotti

J Chem Phys 2019 Apr;150(15):150901

Laboratory of Computational Science and Modeling, Institute des Materiaux, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.

Automated analyses of the outcome of a simulation have been an important part of atomistic modeling since the early days, addressing the need of linking the behavior of individual atoms and the collective properties that are usually the final quantity of interest. Methods such as clustering and dimensionality reduction have been used to provide a simplified, coarse-grained representation of the structure and dynamics of complex systems from proteins to nanoparticles. In recent years, the rise of machine learning has led to an even more widespread use of these algorithms in atomistic modeling and to consider different classification and inference techniques as part of a coherent toolbox of data-driven approaches. Read More

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http://dx.doi.org/10.1063/1.5091842DOI Listing

Enhancement of protein mechanical stability: Correlated deformations are handcuffed by ligand binding.

J Chem Phys 2019 Apr;150(15):155102

Institute of Quantitative Biology and Department of Physics, Zhejiang University, Hangzhou 310027, China.

As revealed by previous experiments, protein mechanical stability can be effectively regulated by ligand binding with the binding site distant from the force-bearing region. However, the mechanism for such long-range allosteric control of protein mechanics is still largely unknown. In this work, we use protein topology-based elastic network model (ENM) and all-atomic steered molecular dynamics (SMD) simulations to study the impact of ligand binding on protein mechanical stability in two systems, i. Read More

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http://dx.doi.org/10.1063/1.5054932DOI Listing

Radical pair intersystem crossing: Quantum dynamics or incoherent kinetics?

J Chem Phys 2019 Apr;150(15):151102

Department of Chemistry, University of Oxford, Physical and Theoretical Chemistry Laboratory, South Parks Road, Oxford OX1 3QZ, United Kingdom.

Magnetic field effects on radical pair reactions arise due to the interplay of coherent electron spin dynamics and spin relaxation effects, a rigorous treatment of which requires the solution of the Liouville-von Neumann equation. However, it is often found that simple incoherent kinetic models of the radical pair singlet-triplet intersystem crossing provide an acceptable description of experimental measurements. In this paper, we outline the theoretical basis for this incoherent kinetic description, elucidating its connection to exact quantum mechanics. Read More

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http://dx.doi.org/10.1063/1.5095204DOI Listing

Analysis of vibrational autoionization of CaF Rydberg states.

J Chem Phys 2019 Apr;150(15):154305

Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

We report calculations of vibrational autoionization rates of CaF Rydberg states, based on the results of a global multi-channel quantum defect theory (MQDT) fit. Our goal is to use intuitive physical models to interpret and extend the results from the MQDT calculations and, in particular, to characterize the physical mechanisms for the interaction between the Rydberg electron and the ion-core. The calculations indicate that, among the six strongly l-mixed core-penetrating (CP) Rydberg series of CaF, the n. Read More

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http://aip.scitation.org/doi/10.1063/1.5091526
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http://dx.doi.org/10.1063/1.5091526DOI Listing
April 2019
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