1,353 results match your criteria Photodiagnosis and Photodynamic Therapy [Journal]


Single visit PDT for basal cell carcinoma - a new therapeutic protocol.

Photodiagnosis Photodyn Ther 2019 Apr 16. Epub 2019 Apr 16.

Skin Department, Foundation Hospital Amaral Carvalho, Jau, São Paulo, Brazil. Electronic address:

Non-melanoma skin cancer is the most prevalent type of cancer in Brazil and worldwide. Topical Photodynamic Therapy is a technique that offers advantages as: excellent aesthetic result, possibility of application for outpatients in ambulatory, and presenting a minimum functional impact of the treated anatomycal site. Fractionated Photodynamic Therapy is a modification of the usual technique in which the full dose of light is delivered in steps separated by a periods of time ("dark intervals"). Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000193012
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.04.016DOI Listing
April 2019
1 Read

In- vitro-activity of additive application of hydrogen peroxide in antimicrobial photodynamic therapy using LED in the blue spectrum against bacteria and biofilm being associated with periodontal disease.

Photodiagnosis Photodyn Ther 2019 Apr 16. Epub 2019 Apr 16.

School of Dentistry, Department of Periodontology, University of Bern, Freiburgstrasse 7, CH-3010, Bern, Switzerland. Electronic address:

Background: Although antimicrobial photodynamic therapy (aPDT) has been shown to be efficient in killing planktonic periodontopathogenic bacteria, its activity on established biofilms is very limited. The aim of the present in-vitro study was to evaluate the potential effect of hydrogen peroxide as a pretreatment for aPDT.

Methods: aPDT consisting of riboflavin as photosensitizer and illumination by a LED lamp emitting in the blue spectrum for 30 s and 60 s (aPDT60) was combined with a pretreatment with 0. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000193007
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.04.015DOI Listing
April 2019
1 Read

The photo-activated and photo-thermal effect of the 445/970 nm diode laser on the mixed biofilm inside root canals of human teeth in vitro: a pilot study.

Photodiagnosis Photodyn Ther 2019 Apr 14. Epub 2019 Apr 14.

Department of Endodontics and Restorative Dentistry, School of Dental Medicine, University of Zagreb, Gundulićeva 5, 10000, Zagreb, Croatia. Electronic address:

Aims: 1) Evaluation of the photo-thermal (PT) and photo-activated (PAD) antibacterial effect of the 445/970 nm diode laser on E. faecalis, S. aureus and C. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.014DOI Listing

Severe oral infection caused by Pseudomonas aeruginosa effectively treated with methylene blue-mediated photodynamic inactivation.

Photodiagnosis Photodyn Ther 2019 Apr 13. Epub 2019 Apr 13.

Pathology Department, School of Dentistry, University of São Paulo, Av. Professor Lineu Prestes 2227, CEP 05508-000, Brazil. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.013DOI Listing

Daylight PDT acts by continuous activation of PpIX.

Photodiagnosis Photodyn Ther 2019 Apr 12. Epub 2019 Apr 12.

Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Skovvej 35, DK-2950 Vedbæk, Denmark. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.012DOI Listing

METHYL AMINOLEVULINATE-BASED PHOTODYNAMIC THERAPY OF BOWEN´S DISEASE: OBSERVATIONAL STUDY OF 21 LESIONS.

Photodiagnosis Photodyn Ther 2019 Apr 12. Epub 2019 Apr 12.

Private clinic of Dr. Alberdi, Madrid, Spain.

Background: Although surgical removal is the treatment of choice in Bowen's disease (BD), there are cases in which by age, comorbidities, use of anticoagulants, location, cosmetic result, or size, it is preferable to use other alternative treatments such as cryotherapy, 5-fluorouracil cream, imiquimod 5% cream or photodynamic therapy (PDT). Efficacy of PDT in BD is supported by substantial research and clinical data.

Objectives: This study aimed to evaluate the long term effectiveness of methyl aminolevulinate-PDT (MAL/PDT) on a wide range of Bowen lesions in different locations and sizes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.011DOI Listing

5-aminolevulinic acid photodynamic therapy with and without Er:YAG laser for actinic keratosis: changes in immune infiltration.

Photodiagnosis Photodyn Ther 2019 Apr 12. Epub 2019 Apr 12.

Department of Dermatology, Faculty of Medicine University of Debrecen, Hungary.

Introduction: Ultraviolet light induced DNA damage, combined with immunosuppression and inflammation are involved in the pathogenesis of actinic keratosis. Photodynamic therapy not only destroys dysplastic cells via tissue destruction and vascular shutdown, but also induces an acute local inflammatory response and activates both the innate and adaptive immune system. In our current work we aimed to compare immunohistochemistry features of inflammatory infiltrate of actinic keratoses after 5-aminolevulinic acid photodynamic therapy with or without Er:YAG laser resurfacing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.010DOI Listing

Influence of final irrigation protocols and type of resin cement on bond strength of glass fiber posts in root dentin previously treated with photodynamic therapy.

Photodiagnosis Photodyn Ther 2019 Apr 6. Epub 2019 Apr 6.

School of Dentistry, University of Passo Fundo, Passo Fundo, RS, Brazil.

Introduction: This study aimed to evaluate the influence of final irrigation protocols and type of resin cement on the bond strength of glass fiber posts (GFPs) in root dentin previously treated with photodynamic therapy (PDT).

Methods: One hundred root canals were prepared up to #4 Gates Glidden drill to receive the GFPs. All samples were subjected to PDT, and randomly divided into five groups (n = 20) according to final irrigation protocol: distilled water + ultrasonic activation [US]; 17% EDTA; QMix; 17% EDTA + US; and QMix + US. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.007DOI Listing

Curettage + microneedling + topical ALA-PDT for the treatment of acral resistant warts: our experience.

Photodiagnosis Photodyn Ther 2019 Apr 6. Epub 2019 Apr 6.

Dermatology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy.

Background: Cutaneous warts are an extremely common problem, whose eradication can be challenging. Topical PDT involves applying a porphyrin precursor, 5-aminolevulinic acid (ALA) or methyl aminolevulinate (MAL) to the affected area. ALA-PDT has been well documented to be successful in the treatment of recalcitrant warts. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.008DOI Listing
April 2019
1 Read

Effects of Photodynamic Therapy with Indocyanine Green on Streptococcus Mutans Biofilm.

Photodiagnosis Photodyn Ther 2019 Apr 6. Epub 2019 Apr 6.

Department of Restorative Dentistry, Faculty of Dentistry, Fırat University, Elazığ, Turkey.

Background: The current procedures for treating tooth decay are not always guaranteed to successfully remove all microorganisms which cause disease. For elimination of bacteria and prevention of their effects, different methods are recommended, such as antibacterial materials and cavity disinfectants. The aim of this study was to compare the antibacterial activity of the photodynamic therapy (PDT) using diode laser with indocyanin green (ICG) on Streptococcus (S. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000183034
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.04.005DOI Listing
April 2019
6 Reads

Algicidal effect of blue light on pathogenic Prototheca species.

Photodiagnosis Photodyn Ther 2019 Apr 6. Epub 2019 Apr 6.

Department of Clinical and Toxicological Analysis, School of Pharmaceutical Sciences, University of Sao Paulo, Sao Paulo, SP, Brazil; BioLambda, Scientific and Commercial LTD, Sao Paulo, SP, Brazil. Electronic address:

Prototheca spp. are pathogenic algae with important zoonotic potential. Most importantly, these algae often infect dairy cattle. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.009DOI Listing
April 2019
4 Reads

Combined Treatment of Nonresectable Cholangiocarcinoma Complicated by Obstructive Jaundice.

Photodiagnosis Photodyn Ther 2019 Apr 6. Epub 2019 Apr 6.

Prokhorov General Physics Institute of the Russian Academy of Sciences, Vavilov str., 38, Moscow, 119991, Russia; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), Kashirskoye sh., 31, Moscow, 115409, Russia. Electronic address:

Background: The five-year survival rate for successful surgical treatment of cholangiocellular cancer is only 20-40%, and in the case of an unresectable tumor, the life expectancy does not exceed 6 months. These terms decrease with the presence of jaundice due to the spread of the tumor process along the bile ducts, leading to their obstruction. The outcomes of patients with nonresectable bile duct carcinoma complicated by obstructive jaundice have been shown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.006DOI Listing
April 2019
3 Reads

A consideration of antimicrobial photodynamic therapy using the plaque disclosing solution on Streptococcus mutans.

Photodiagnosis Photodyn Ther 2019 Apr 2. Epub 2019 Apr 2.

Division of Photomedical Dentistry, Department of Oral Science, Graduate School of Dentistry, Kanagawa Dental University, 82 Inaoka-cho, Yokosuka, Kanagawa 238-8580, Japan. Electronic address:

Objectives: Photodynamic therapy with a bactericidal action is called antimicrobial photodynamic therapy (aPDT), a method of staining an object with a photosensitizing dye and then sterilizing by irradiating a dye excitation wavelength. In this study, we aimed to investigate caries pathogenic bactericidal method in a site difficult to mechanically remove, examined aPDT effect onStreptococcus mutans (S. mutans) which is a typical caries pathogenic bacteria by applying the plaque disclosing solution as photosensitizing dye. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.003DOI Listing
April 2019
1 Read

Curcumin-mediated photodynamic inactivation (PDI) against DH5α contaminated in oysters and cellular toxicological evaluation of PDI-treated oysters.

Photodiagnosis Photodyn Ther 2019 Apr 2. Epub 2019 Apr 2.

Laboratory of Food Science and Human Health, College of Food Science and Engineering, Ocean University of China, Qingdao, China. Electronic address:

The objective of this study was to evaluate the bactericidal effect of curcumin (CUR)-mediated photodynamic inactivation (PDI) against Escherichia coli DH5α in vitro and in oysters, then further investigate the edible security of PDI-treated oysters based on cellular toxicological methods. First of all, DH5α cells were irradiated by a 470 nm LED light source with an energy density of 3.6 J/cm. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.002DOI Listing

Study of the efficacy of N-methyl glucamine antimoniate (Sb) associated with photodynamic therapy using liposomal chloroaluminium phthalocyanine in the treatment of cutaneous leishmaniasis caused by Leishmania (L.) amazonensis in C57BL6 mice.

Photodiagnosis Photodyn Ther 2019 Apr 2. Epub 2019 Apr 2.

Faculty of Medicine, Dermatomycology Laboratory, University of Brasília, Campus Darcy Ribeiro, 70910-900 Brasília/DF, Brazil.

Background: Pentavalent antimonials remain first-line drugs in the treatment of cutaneous leishmaniasis (CL); however, adverse effects and drug resistance have led to the search for less toxic and more effective treatments. As an alternative, topical phthalocyanine has been studied and its efficacy and low toxicity demonstrated. We aimed to study the in vivo efficacy of N-methyl glucamine antimoniate (NMG) associated with photodynamic therapy (PDT) with topical liposomal chloroaluminium phthalocyanine (AlClPC) in the treatment of experimental CL by L. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.004DOI Listing
April 2019
2 Reads

Combined the simple shaving with photodynamic therapy for refractory Bowen disease.

Photodiagnosis Photodyn Ther 2019 Apr 2. Epub 2019 Apr 2.

Department of Dermatology, Xiangya <-- -->Hospital, Central South University, 87, Xiangya Road, Changsha, 41008, Hunan, China. Electronic address:

Bowen Disease (BD), also known as squamous cell carcinoma in situ, requires actively treatments. Photodynamic therapy (PDT) has been widely recommended to treat for BD. However, there are still a few BD patients with poor efficacy and recurrence after PDT treatment. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.04.001DOI Listing

Influence of phototherapy on bond strength and failure modes of enamel bonded to ceramic and metallic brackets with different surface treatment regimes.

Authors:
Salem Almoammar

Photodiagnosis Photodyn Ther 2019 Mar 30. Epub 2019 Mar 30.

Department of Paediatric Dentistry and Orthodontics, College of Dentistry, King Khalid University, Saudi Arabia. Electronic address:

Aim: The aim of the current study was to assess efficacy of phototherapy on mode of failure and shear bond strength among different brackets in combination with dissimilar conditioning regimens on enamel surface MATERIAL AND METHODS: Ninety maxillary premolars were arbitrarily assigned into six groups (n = 15 each) based on surface conditioning of enamel. Group 1 and group 2 surface treated with total etch + rinse. Group 3 and group 4 surface conditioned with Er,Cr:YSGG. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.021DOI Listing
March 2019
3 Reads

In vivo characterization of large cell acanthoma by cellular resolution optical coherent tomography.

Photodiagnosis Photodyn Ther 2019 Mar 30. Epub 2019 Mar 30.

Department of Dermatology, MacKay Memorial Hospital, Taipei, Taiwan; Department of Medicine, Mackay Medical College, New Taipei City, Taiwan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.020DOI Listing
March 2019
1 Read

TREATMENT OF SUPERFICIAL BASAL CELL CARCINOMA WITH PHOTODYNAMIC THERAPY. OBSERVATIONAL STUDY IN 22 PATIENTS WITH 5-AMINOLAEVULINIC ACID AND METHYL AMINOLAEVULINATE.

Photodiagnosis Photodyn Ther 2019 Mar 23. Epub 2019 Mar 23.

Servicio de Dermatología, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain.

Background: There is limited literature on efficacy in 5-aminolaevulinic acid (BF-200 ALA) and methyl-5-aminolaevulinate (MAL) for superficial basal cell carcinoma (sBCC).

Aims: To investigate the efficacy and safety of PDT in sBCC.

Methods: Analytical observational study between January 2014 and January 2017. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000193005
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.03.018DOI Listing
March 2019
3 Reads

Evaluation of laser fluorescence in combination with photosensitizers for detection of demineralized lesions.

Photodiagnosis Photodyn Ther 2019 Mar 23. Epub 2019 Mar 23.

Iranian Medical Laser Association, Tehran, Iran.

Background And Objectives: Early detection of caries plays an important role in its prognosis. This study sought to assess the efficacy of laser fluorescence alone and in combination with photosensitizers for detection of demineralized smooth-surface lesions of permanent teeth.

Materials And Methods: This in vitro experimental study was conducted on 60 extracted sound premolars. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.019DOI Listing

Role of various nanoparticles in photodynamic therapy and detection methods of singlet oxygen.

Photodiagnosis Photodyn Ther 2019 Mar 23. Epub 2019 Mar 23.

Faculty of Chemistry, University of Warsaw, ul. Pasteura 1, 02-093 Warsaw, Poland.

In this review article we described the applications of various nanoparticles that can be used for photodynamic therapy (PDT), such as: plasmonic nanoparticles, quantum dots and upconversion nanoparticles. In comparison with typical organic photosensitizers such as hematoporphyrins, they exhibit higher photostability and resistance to enzymatic degradation, and hence, in some cases, they could replace organic photosensitizers in PDT therapy. It has also been found that the presence of plasmonic noble metal nanoparticles increases the efficiency of conjugated standard photosensitizers. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.016DOI Listing

In Vitro Comparison of the Effect of Photodynamic Therapy with Curcumin and Methylene Blue on Candida albicans Colonies.

Photodiagnosis Photodyn Ther 2019 Mar 23. Epub 2019 Mar 23.

Biophysics department, Islamic Azad University, Science and Research Branch, Tehran, Iran. Electronic address:

Background And Aim: Candida albicans (C. albicans) causes oral fungal infections. Considering the high prevalence of candidiasis, the toxicity of antifungal drugs, and the fungistatic property which develops drug-resistant species, the present study aimed to assess the effect of photodynamic therapy (PDT) with curcumin (CUR) and methylene blue (MB) photosensitizers and lasers with different exposure parameters on C. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.017DOI Listing
March 2019
1 Read

Efficient in vitro photodynamic inactivation using repetitive light energy density on Candida albicans and Trichophyton mentagrophytes.

Photodiagnosis Photodyn Ther 2019 Mar 22. Epub 2019 Mar 22.

Departamento de Óptica del Instituto Nacional de Astrofísica Óptica y Electrónica, Tonantzintla, Puebla, Mexico; Cátedras-CONACYT, Mexico. Electronic address:

Background: We compared the effectiveness of a single irradiation versus repetitive irradiation of light, for in vitro photodynamic inactivation (PDI) of Candida albicans and Trichophyton mentagrophytes, by using methylene blue (MB) and rose bengal (RB) as photosensitizers (PS).

Methods: MB from 5 to 60 µM and RB from 0.5 to 10 μM, with energy densities from 10 to 60 J/cm, were tested in C. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.015DOI Listing

CCL8 enhances sensitivity of cutaneous squamous cell carcinoma to photodynamic therapy by recruiting M1 macrophages.

Photodiagnosis Photodyn Ther 2019 Mar 19. Epub 2019 Mar 19.

Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China. Electronic address:

Background: Antitumor immunity induced by photodynamic therapy (PDT) is believed to depend on the degree of local and systemic inflammation. The recruitment of leukocytes, in particular by the chemokine CCL8, to the sites of tissue damage has been strongly associated with the initiation of inflammatory reactions.

Objective: To evaluate whether and how CCL8 enhances the immune response against tumors in 5-aminolevulinic acid (ALA)-mediated PDT. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.014DOI Listing

Influence of final irrigation protocols and endodontic sealer on bond strength of root filling material with root dentin previously treated with photodynamic therapy.

Photodiagnosis Photodyn Ther 2019 Mar 19. Epub 2019 Mar 19.

School of Dentistry, University of Passo Fundo, Passo Fundo, RS, Brazil.

Introduction: The aim of this study was to evaluate the influence of final irrigation protocols and endodontic sealer on bond strength of root filling material on root dentin previously treated with photodynamic therapy (PDT).

Methods: One hundred root canals were prepared up to #F3 file of Pro-Taper system to receive the root filling material. All samples were submitted to PDT and randomly divided into five groups (n = 20) according to final irrigation protocols: Group 1-distilled water + ultrasonic activation (US); Group 2-17% EDTA; Group 3-QMix; Group 4-17% EDTA + US; Group 5-QMix + US. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.013DOI Listing

SCIENTIFIC EVIDENCE IN ANTIMICROBIAL PHOTODYNAMIC THERAPY: AN ALTERNATIVE APPROACH FOR REDUCING CARIOGENIC BACTERIA.

Photodiagnosis Photodyn Ther 2019 Mar 18. Epub 2019 Mar 18.

Postgraduate Program in Medical Microbiology, Federal University of Ceara, Brazil, Faculty of Medicine, Federal University of Ceara, Brazil; Postgraduate Program in Dentistry, Federal University of Ceara, Brazil, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceara, Brazil. Electronic address:

Several studies of antimicrobial photodynamic therapy (aPDT) have been performed to verify the efficiency of this treatment against caries-related microorganisms. Thus, the aim of this study is to describe the characteristics of aPDT and to review the literature regarding its effects on cariogenic microorganisms organized in biofilms and/or caries lesions. The literature was searched for reviews and original papers about aPDT and its outcomes against Streptococcus mutans as well as other caries-associated microorganisms or caries lesions. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000183044
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.03.012DOI Listing
March 2019
4 Reads

Successful treatment of oral human papilloma by local injection 5-aminolevulinic acid-mediated photodynamic therapy: a case report.

Photodiagnosis Photodyn Ther 2019 Mar 16. Epub 2019 Mar 16.

Department of Stomatology, Beijing Hospital, National Center of Gerontology, Beijing 100730, PR China.

Oral human papilloma (HPV) virus is very common in patients. Deep location of lesions can lead to poor therapeutic effects. We are reporting a case of 52-year-old male who was diagnosed of oral papilloma on the left side of the palatoglossal arch. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.011DOI Listing

THE TARGETING ABILITY OF FLUORESCENT QUANTUM DOTS TO THE FOLATE RECEPTOR RICH TUMORS.

Photodiagnosis Photodyn Ther 2019 Mar 15. Epub 2019 Mar 15.

Centre de Recherche en Automatique de Nancy, Centre National de la Recherche Scientifique UMR 7039, Université de Lorraine, Campus Sciences, Boulevard des Aiguillette, 54506 Vandoeuvre-lès-Nancy, France; Surgical Department, Institut de Cancérologie de Lorraine, 6 avenue de Bourgogne, 54519 Vandoeuvre-lès-Nancy, France. Electronic address:

Background: Quantum dots (QDs) bring new insights in cancer theranostics. Exceptional brightness together with the simple possibility to modify surface with targeting molecules make QDs attractive agents in fluorescence guided surgery and photodynamic therapy. Currently, many targeted QDs have been developed for theranostic purpose. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000193004
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.03.010DOI Listing
March 2019
5 Reads

Photodynamic activity and DNA binding studies of Pd@SiO core-shell nanoparticles in vitro.

Photodiagnosis Photodyn Ther 2019 Mar 9. Epub 2019 Mar 9.

Dept. of Chemistry, St. Joseph's College of Engineering, Chennai, Tamil Nadu, India.

Metal-semiconductor core-shell type Pd@SiO nanoparticles (NPs) were successfully synthesized by Stober's method and the product was characterized by UV-Visible, XRD, FT-IR, SEM, HR-TEM and EDX techniques. In vitro Photodynamic activity and DNA binding studies of Pd@SiO core shell nanoparticles were studied. Cell viability of the core-shell nanoparticles against HeLa cell line was screened by MTT assay after exposing at different light doses. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000183024
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.03.008DOI Listing
March 2019
3 Reads

Quantitative Light-Induced Fluorescence Assessment of White Spots Following Semi-Rapid Maxillary Expansion.

Photodiagnosis Photodyn Ther 2019 Mar 9. Epub 2019 Mar 9.

Assistant Professor, Ordu University, Faculty of Dentistry, Department of Orthodontics, Ordu, Turkey. Electronic address:

Background: This study aimed to investigate if the semi-rapid maxillary expansion (SRME) can cause white spot lesion (WSL) formation using quantitative light-induced fluorescence digital (QLF-D).

Methods: The SRME group comprised 15 patients (9 girls, 6 boys; 13.5 ± 1 years) who had transverse maxillary deficiency and underwent expansion with full-coverage expanders. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.009DOI Listing

Photophysical properties and photodynamic therapy activities of detonated nanodiamonds-BODIPY-phthalocyanines nanoassemblies.

Photodiagnosis Photodyn Ther 2019 Mar 6. Epub 2019 Mar 6.

Centre for Nanotechnology Innovation, Department of Chemistry, Rhodes University, South Africa. Electronic address:

This work reports on the synthesis of nanoassemblies of supramolecular hybrids containing detonated nanodiamonds (DNDs) covalently linked to halogenated BODIPY (DNDs-BODIPY) by amide bond, followed by π-π stacking of 2,9,16,23-Tetrakis[4-(N-methylpyridyloxy)]-phthalocyanine (ZnTPPcQ) on the DNDs-BODIPY conjugate, to form nanoassembly represented as ZnTPPcQ-DNDs-BODIPY. ZnTPPcQ-DNDs-BODIPY showed higher singlet oxygen quantum yield of 0.50 in water. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000193001
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.03.007DOI Listing
March 2019
3 Reads

Atypical Endometrial Hyperplasia Diagnosed by Hysteroscopic Photodynamic Diagnosis using 5-Aminolevulinic Acid.

Photodiagnosis Photodyn Ther 2019 Mar 5. Epub 2019 Mar 5.

Department of Obstetrics and Gynecology, Keio University School of Medicine, Tokyo, 160-8582, Japan.

Endometrial cancer is diagnosed by endometrial biopsy, imaging and hysteroscopy, but it is sometimes difficult to find small lesions. 5-aminolevulinic acid (5ALA) forms protoporphyrin IX, which accumulates in tumors and fluoresces upon light irradiation. 5ALA is used for photodynamic diagnosis (PDD) for detecting malignant diseases. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.006DOI Listing
March 2019
3 Reads

Comparison of high and low molecular weight chitosan as in-vitro boosting agent for photodynamic therapy against Helicobacter pylori using methylene blue and endoscopic light.

Photodiagnosis Photodyn Ther 2019 Mar 2. Epub 2019 Mar 2.

Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South of Korea. Electronic address:

Background: We reported in previous study that the photodynamic therapy (PDT) of Helicobacter pylori(H. pylori) could more potentiate the bactericidal effect by adding chitosan. As a next step, we investigated to compare the bactericidal effects of low molecular weight (LMW) combined with phototherapy to high molecular weight (HMW) chitosan. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.005DOI Listing
March 2019
1 Read

Is phototherapy effective in the management of post-operative endodontic pain? A systematic review of randomized controlled clinical trials.

Photodiagnosis Photodyn Ther 2019 Mar 2. Epub 2019 Mar 2.

Department of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.

Background: The aim of the current review was to answer the P.I.C. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.003DOI Listing

Antimicrobial Efficacy of Photodynamic Therapy Using Two Different Light Sources on the Titanium-Adherent Biofilms of Aggregatibacter actinomycetemcomitans: An in vitro study.

Photodiagnosis Photodyn Ther 2019 Mar 2. Epub 2019 Mar 2.

Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background: Antimicrobial photodynamic therapy (aPDT), is a promising approach proposed as an adjunct for the decontamination of dental implant surfaces. This study aimed to investigate the effect of aPDT with laser or light emitting diode (LED) compared with conventional chlorhexidine treatment on the titanium-attached biofilms ofAggregatibacter actinomycetemcomitans.

Methods And Materials: Thirty-six acid-etched and sandblasted (SLA) titanium discs were allocated to six groups and incubated with the titanium-adherent biofilms of A. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.004DOI Listing
March 2019
1 Read

What is the most relevent factor during ALA-PDT? A multi-center, open clinical pain score research about actinic keratosis, acne and condylomatata acuminata.

Photodiagnosis Photodyn Ther 2019 Mar 2. Epub 2019 Mar 2.

Institute of Photomedicine, Shanghai Skin Disease Hospital, Tongji University, School of Medicine, Shanghai, China. Electronic address:

Background: To date, it has been reported that the intrinsic factors(lesions location, lesions area, disease types) and extrinsic factors(fluence rate) contribute to the pain during 5-aminolevulinic acid photodynamic therapy (ALA-PDT). But there are few studies on pain during ALA-PDT and lack of sufficient clinical evidence related to the pain intensity.

Objective: To investigate pain intensity and its relative factors during ALA-PDT and to provide clinical implication. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.001DOI Listing
March 2019
2 Reads

Acanthopanacis Cortex extract: a novel photosensitizer for head and neck squamous cell carcinoma therapy.

Photodiagnosis Photodyn Ther 2019 Mar 2. Epub 2019 Mar 2.

Department of Oral Pathology, Dental Science Research Institute, School of Dentistry, Chonnam National University, Gwangju, 61186, Republic of Korea. Electronic address:

Objectives: The aim of this study was to develop a novel photosensitizer from traditional plant extracts and to investigate the photodynamic therapy (PDT) effect and mechanism of action of the novel photosensitizer on KB and Hep-2 cells.

Methods: Fluorescence emission, cell viability, and intracellular distribution of candidates were analyzed to screen potential photosensitizers from traditional plant extracts. Cellular reactive oxygen species (ROS) quantification, Annexin V-FITC/PI staining, and western blotting were performed to explore the mechanism of cell death in KB and Hep-2 cells. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000183040
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.02.020DOI Listing
March 2019
5 Reads

A combination of 2940-nm laser and photodynamic therapy in treatment for recalcitrant facial flat warts.

Photodiagnosis Photodyn Ther 2019 Mar 2. Epub 2019 Mar 2.

Department of Dermatology, Xi Jing Hospital, the Fourth Military Medical University, Xi'an, 710032, PR China. Electronic address:

Background: Photodynamic therapy (PDT) is one of the treatment options for generalized facial flat warts, which results in elimination of virus and inhibition of proliferation of warts due to photochemical and phototoxic reactions. In this research, we attempted to evaluate the efficacy and safety profiles of a combination of 2940-nm laser and PDT for the treatment of generalized recalcitrant facial flat warts.

Methods: Retrospective analysis of the patients with recalcitrant facial warts was performed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.03.002DOI Listing
March 2019
1 Read

EtNBSe-PDT inhibited proliferation and induced autophagy of HNE-1 cells via downregulating the Wnt/β-catenin signaling pathway.

Photodiagnosis Photodyn Ther 2019 Mar 1. Epub 2019 Mar 1.

Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha, Hunan, China. Electronic address:

Background: Increasing evidence has suggested that autophagy may play a resistant role during photodynamic therapy (PDT). The Wnt/β-catenin pathway is tightly involved in cell proliferation and autophagy. In this study, we aimed to determine the influence of 5-Ethylamino-9-diethylaminobenzo[a]phenoselenazinium (EtNBSe) mediated PDT (EtNBSe-PDT) on autophagy, proliferation and Wnt/β-catenin pathway in human NPC cell line (HNE-1 cells), and further explore the underlying crosstalk between them. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.024DOI Listing
March 2019
2.014 Impact Factor

Application of the Z-scan technique for the detection of CFCDNA (cell-free circulating DNA) and urine DNA (uDNA) in patients with bladder cancer.

Photodiagnosis Photodyn Ther 2019 Feb 26. Epub 2019 Feb 26.

Laboratório de Análises Clínicas da Faculdade de Medicine do ABC, Av. Lauro Gomes, 2000, CEP 09060-870, Santo André, SP, Brazil; Departamento de Ciências Farmacêuticas da Universidade Federal de São Paulo, Rua São Nicolau, 210, CEP: 09913-030, Diadema, SP, Brazil. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.022DOI Listing
February 2019
1 Read

EXCELLENT COSMETIC RESULT OF DAYLIGHT PHOTODYNAMIC THERAPY FOR FACIAL FLAT WARTS IN A CHILD.

Photodiagnosis Photodyn Ther 2019 Feb 26. Epub 2019 Feb 26.

Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.021DOI Listing
February 2019

Antibacterial and photodynamic effects of some plant extracts for cavity disinfection.

Photodiagnosis Photodyn Ther 2019 Feb 26. Epub 2019 Feb 26.

Yeditepe University Faculty of Engineering, Department of Genetics and Bioengineering, Istanbul, Turkey.

Background: In current dentistry treatments, with the aim of preventive approach it is argued that removing only the infected layer of dentin is sufficient for cavity preparation. However it is impossible to be sure with bare eyes that infected layer was completely removed or not. In addition, the cause of secondary caries and post operative sensitivities has been reported as residual bacteria in some studies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.025DOI Listing
February 2019
2.014 Impact Factor

Study of pharmacokinetics and cutaneous photosensitization of Hemoporfin in healthy volunteers.

Photodiagnosis Photodyn Ther 2019 Feb 26. Epub 2019 Feb 26.

Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co, Ltd, Shanghai, 201210, China. Electronic address:

Background: Hemoporfin is a porphyrin-based photosensitizer and has been used for photodynamic therapy of port wine stain birthmarks in China. This study assessed the pharmacokinetics and cutaneous photosensitization of Hemoporfin in healthy volunteers.

Methods: Sixteen healthy subjects received a single intravenous infusion injection of Hemoporfin (5 mg/kg). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.023DOI Listing
February 2019

Indocyanine green-based adjunctive antimicrobial photodynamic therapy for treating chronic periodontitis: A randomized clinical trial.

Photodiagnosis Photodyn Ther 2019 Feb 23. Epub 2019 Feb 23.

Department of Periodontology, Operative and Preventive Dentistry, Bonn University, Dental Faculty, 53111 Bonn, Germany; Center of Applied Medical Laser Research and Biomedical Optics (AMLaReBO), Bonn University, 53111, Germany.

Background: The objective was to evaluate the efficiency of indocyanine green (ICG)-based adjunctive antimicrobial photodynamic therapy (aPDT) in a prospective clinical study regarding non-surgical treatment of chronic periodontitis.

Methods: Affected teeth of twenty patients were treated with scaling and root planing (control group). Using a split-mouth design, two quadrants received additional ICG-based (perio green®, 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.019DOI Listing
February 2019
1 Read

Influence of antimicrobial photodynamic therapy in carious lesion. Randomized split-mouth clinical trial in primary molars.

Photodiagnosis Photodyn Ther 2019 Feb 23. Epub 2019 Feb 23.

Department of Restorative Dentistry, Ribeirão Preto School of Dentistry, University of São Paulo, Brazil. Electronic address:

Background: The literature has presented many studies regarding photodynamic antimicrobial therapy (aPDT). However, the great variety of protocols to be used can directly influence its effectiveness in reducing microorganisms. The aim of this randomized split-mouth clinical study was to evaluate the effect of aPDT in the reduction of Streptococcus mutans and their effect on restorations performed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.018DOI Listing
February 2019
2 Reads

Mueller matrix imaging of prostate bulk tissues; Polarization parameters as a discriminating benchmark.

Photodiagnosis Photodyn Ther 2019 Feb 20. Epub 2019 Feb 20.

Department of Medical Physics and Biomedical Engineering, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

The polarimetry imaging technique has provided a powerful tool for discriminating the normal from the cancerous tissues. In this paper, based on the backscattering Mueller matrix imaging of prostate bulk tissues, (received immediately after surgery without any further processing), we have extracted the characteristic features of the Mueller matrix images. In order to provide a quantitative and more accurate comparison, three different methods have been used; the Mueller matrix polar decomposition (MMPD), the Mueller matrix transformation (MMT) and the frequency distribution histograms (FDHs) and their central moment parameters. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.017DOI Listing
February 2019

Can red fluorescence be useful in diagnostic decision making of residual dentin caries?

Photodiagnosis Photodyn Ther 2019 Feb 20. Epub 2019 Feb 20.

Department of Preventive Dentistry & Public Oral Health, BK21 PLUS Project, Oral Science Research Institute, Yonsei University College of Dentistry, 120-752, 50 Yonsei-ro, Seodaemun-Gu, Seoul, Republic of Korea. Electronic address:

Introduction: A diagnosis based on traditional methods can differ under the same tooth condition. Additional diagnostic tools are required to overcome this limitation. QLF technology is a viable method for detecting residual caries and is increasingly being used to detect dentin-level residual caries. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15721000193002
Publisher Site
http://dx.doi.org/10.1016/j.pdpdt.2019.02.016DOI Listing
February 2019
1 Read

Antimicrobial Photodynamic Therapy associated with long term success in endodontic treatment with separated instruments: A case report.

Photodiagnosis Photodyn Ther 2019 Feb 20. Epub 2019 Feb 20.

Department of Dentistry, Pontifícia Universidade Católica de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. Electronic address:

This paper describes a case with a 5- year follow-up of Antimicrobial Photodynamic Therapy (aPDT) associated with long-term success in endodontic treatment in a tooth with separated instruments. The patient presented with a tooth exhibiting a periapical lesion, slight swelling, and severe pain. A radiograph revealed the presence of two separated files in the middle and apical thirds of the mesial root on a lower first molar. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.015DOI Listing
February 2019
1 Read

Successful treatment of chromoblastomycosis using ALA-PDT in a patient with leukopenia.

Photodiagnosis Photodyn Ther 2019 Feb 12. Epub 2019 Feb 12.

Department of Dermatology, Nanfang Hospital, Southern Medical University, 1838 North Avenue, Guangzhou 510515, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.013DOI Listing
February 2019
2 Reads
2.014 Impact Factor

Folate-directed zinc (II) phthalocyanine loaded polymeric micelles engineered to generate reactive oxygen species for efficacious photodynamic therapy of cancer.

Photodiagnosis Photodyn Ther 2019 Mar 12;25:480-491. Epub 2019 Feb 12.

Department of Organic and Pharmaceutical Technology, Faculty of Chemistry, Wroclaw University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370, Wroclaw, Poland. Electronic address:

Targeted and effective drug transport is becoming an attractive option in cancer therapy since it can improve drug efficacy and reduce drugs' side effects in normal tissues. In addition to using specific surface ligand molecules, the selective drug delivery can be accomplished via enhanced permeability and retention effect. Therefore, in our studies, we entrapped zinc (II) phthalocyanine (ZnPc) - a second generation photosensitizer - in folate-functionalized micelles of the biocompatible, FDA-approved for biomedical application diblock copolymer methoxypoly(ethylene oxide)-b-poly(L-lactide) (mPEG-b-PLLA) and its derivative with folate (FA) attached to the end of PEG chain (FA-PEG-b-PLLA). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pdpdt.2019.02.014DOI Listing
March 2019
1 Read