10 results match your criteria Phencyclidine PCP-Related Psychiatric Disorders

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Effects of repeated phencyclidine administration on adult hippocampal neurogenesis in the rat.

Synapse 2006 Jul;60(1):56-68

Department of Psychiatry, Juntendo University School of Medicine, Bunkyo, Tokyo, Japan.

Dysfunctional maturation of neural networks, particularly hippocampus-prefrontal networks, may be of particular interest in determining the pathophysiology of schizophrenia. Phencyclidine (PCP)-induced symptoms in humans appear to offer a more complete model of schizophrenia than do amphetamine-induced symptoms. This study investigated the effects of intermittent i. Read More

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Serial analysis of gene expression in methamphetamine- and phencyclidine-treated rodent cerebral cortices: are there common mechanisms?

Ann N Y Acad Sci 2004 Oct;1025:57-61

Department of Psychiatry, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.

Pharmacological actions of methamphetamine (METH) and phencyclidine (PCP) are different, but both of them can induce similar psychiatric disorders including abuse, intoxication, withdrawal, and psychotic symptoms like those of schizophrenia. These mental disorders are caused not only by their direct pharmacological effects, but also by secondary brain damage containing gene expression changes. In order to broadly grasp these alterations, we used serial analysis of gene expression (SAGE), a transcriptome analysis. Read More

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October 2004

[Trends in drugs-of-abuse in Los Angeles County].

F Moriya

Nihon Hoigaku Zasshi 1994 Jun;48(3):185-90

Department of Legal Medicine, Okayama University Medical School.

Trends in major drugs-of-abuse, cocaine, heroin/morphine, phencyclidine (PCP), and amphetamines, in Los Angeles County were reported. Death toil of drug abusers in Los Angeles County climbed up high in 1986 due to dramatic increase in cocaine-related deaths. Cocaine-related deaths were responsible for 66. Read More

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Legal issues associated with PCP abuse--the role of the forensic expert.

NIDA Res Monogr 1986 ;64:229-36

These cases illustrate some of the complex issues associated with PCP-related litigation. The concept that malice is implied when an experienced drug user commits a crime while under the influence of the drug is not held in most states, at the present time. The authors have now reviewed in detail four cases of unexpected death following the use of neck holds in PCP-intoxicated individuals. Read More

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[Phencyclidine, a drug which induces psychosis: its neuropharmacological actions].

Yakubutsu Seishin Kodo 1984 Sep;4(2):133-47

Phencyclidine (PCP) is a major drug of abuse as well as a 'drug of choice' among substance abusers in the U. S. A. Read More

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September 1984

Characteristics of victims of PCP-related deaths in Los Angeles County.

J Toxicol Clin Toxicol 1982 Nov;19(9):997-1004

The characteristics of the 104 persons who died in Los Angeles County in 1980 where PCP use was involved, have been studied. A majority of these victims were Black (73%), males (85%), in their twenties (20-29 (58%)), and the victim of a homicide (52%). In only 14% of these cases was there a fatal overdose of PCP alone or in combination with other drugs. Read More

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November 1982

A study of 44 PCP-related deaths.

Int J Addict 1982 Oct;17(7):1175-84

Data on 80 PCP-related deaths, occurring in a 12-month period in 1977-1978, were obtained from the files of the Los Angeles County Coroner. Of these deaths, 44 cases were evaluated by means of the psychological autopsy procedure. This procedure involves abstracting data from available records of the decedent and interviewing persons having personal or professional knowledge of the decedent's life history. Read More

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October 1982

Violence associated with phencyclidine abuse.

Am J Psychiatry 1979 Dec;136(12):1584-6

Violence associated with chronic phencyclidine (PCP) abuse was investigated by administering a structured interview to 16 chronic PCP abusers. A more intensive study was done of another individual who committed murder and self-mutilation under the influence of PCP. The results suggest that there is no consistent association between PCP-related violence and a history of violence not related to drug or alcohol abuse. Read More

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December 1979
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