1,476 results match your criteria Peroneal Mononeuropathy


Nerve Blocks: Part II. Lower Extremity.

Am Fam Physician 2020 Jun;101(11):669-679

Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

Family physicians use anesthesia to provide diagnostic and procedural analgesia for conditions such as neuropathies, fracture reduction, foreign body removals, and complex wound management. Local infiltration of anesthetics is commonly used in this setting because of the ease of use, safety, and effectiveness of the procedure. Nerve blocks are a specific regional anesthesia technique that blocks nerve function distal to the injection site. Read More

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Closed plication is a safe and effective method for treating popliteal vein aneurysm.

J Vasc Surg Venous Lymphat Disord 2020 May 20. Epub 2020 May 20.

Section of Vascular Surgery, Department of Surgery, University of Michigan, Ann Arbor, Mich. Electronic address:

Background: Popliteal vein aneurysms are a rare vascular anomaly first reported in the 1980s. Degeneration of elastic fibers and smooth muscle cell reduction, possibly secondary to inflammation, are implicated as integral steps in the development of these aneurysms. Given the rarity of this clinical entity, significant controversy exists regarding ideal treatment strategies, including the role of observation, medical management with anticoagulation, and surgical intervention. Read More

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http://dx.doi.org/10.1016/j.jvsv.2020.04.026DOI Listing

Superficial peroneal nerve compression due to peroneus brevis muscle herniation.

Authors:
Michele Foresti

J Radiol Case Rep 2019 Nov 30;13(11):10-17. Epub 2019 Nov 30.

Radiology Unit, Department of Diagnostic Imaging and Laboratory Medicine, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.

Muscle hernias of the extremities most commonly occur in the leg, between the knee and ankle. Symptomatic muscle hernias in the leg are rare cause of chronic leg pain and neuropathy, and not routinely encountered in surgical practice. Although this condition is especially an esthetic problem, with palpable subcutaneous soft tissue mass, it can lead to spontaneous pain, cramp, local tenderness or potentially neuropathic symptoms. Read More

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http://dx.doi.org/10.3941/jrcr.v13i11.3757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060001PMC
November 2019

[Design and application of prevention baffle for foot drop in suspension bed].

Zhonghua Shao Shang Za Zhi 2020 Feb;36(2):131-132

Department of Gynaecology, the First Hospital of Jilin University, Changchun 130021, China.

Suspension bed are often used to treat and nurse the wounds of burn patients in clinic. Because of the suspension force, the patients' activities are limited, and they stay in bed for a long time, which is very easy to cause foot drop, affecting the recovery of the patients. Aiming at this problem, we designed and made a foot drop prevention baffle made of stainless steel, which could withstand the buoyancy of the suspension bed, adjust the feet forwardly and backwardly, to the left and right according to the height of the patients and the distance of the feet to be separated, and keep the foot in a positive and external rotation position according to the comfort of the patients, which achieved good results in clinical application. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1009-2587.2020.02.009DOI Listing
February 2020

Modern treatment of perineuriomas: a case-series and systematic review.

BMC Neurol 2020 Feb 13;20(1):55. Epub 2020 Feb 13.

Department of Neurosurgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Background: Perineuriomas are rare benign peripheral nerve sheath tumours of perineurial cell origin and can be classified into intraneural and extraneural perineuriomas. They most commonly present a mononeuropathy of gradual onset and slow progression, resulting in progressive neurological deficits like hypoesthesia or motor weakness. Therapy is still variable. Read More

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http://dx.doi.org/10.1186/s12883-020-01637-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017529PMC
February 2020

PMP22 Gene-Associated Neuropathies: Phenotypic Spectrum in a Cohort from India.

J Mol Neurosci 2020 May 28;70(5):778-789. Epub 2020 Jan 28.

Department of Neurology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, 560029, India.

Reports of spectrum of clinical manifestations in PMP22 gene-associated neuropathies (duplication/mutations) are scarce. To identify the frequency of PMP22 gene variations and establish their genotype-phenotype correlation. Patients with suspected genetic demyelinating neuropathy (n = 128) underwent evaluation for copy number variations and point mutations in PMP22 gene by multiplex ligation-dependent probe amplification (MLPA) and direct sequencing respectively. Read More

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http://dx.doi.org/10.1007/s12031-020-01488-wDOI Listing
May 2020
2.343 Impact Factor

Optimized Design of a Variable Viscosity Link for Robotic AFO.

Conf Proc IEEE Eng Med Biol Soc 2019 07;2019:6220-6223

Herein we present the development of a novel Ankle Foot Orthosis for gait support of people with foot-drop symptoms. The developed AFO uses an elastic link mechanism to brake the ankle joint during initial contact, thus mitigating foot-slap, and an integrated energy store-and-release mechanism to support toe lift in the swing phase, thus mitigating toe-drag. This paper presents improvements in the braking-holding power of the elastic link mechanism over its previous version, the torque-angle characteristics of the developed AFO with the renewed elastic link, and a pilot test with one person with foot-drop symptoms to verify the proposed functions of the developed AFO. Read More

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http://dx.doi.org/10.1109/EMBC.2019.8856773DOI Listing

Pilot Study of Cadence, a Novel Shoe for Patients with Foot Drop.

Conf Proc IEEE Eng Med Biol Soc 2019 07;2019:5291-5296

Foot Drop is a mobility disorder that limits ankle dorsiflexion, complicating the swing phase of gait and balance. It is a common result of a neurological injury or disease such as stroke, cerebral palsy or multiple sclerosis. Here we present Cadence, a low-cost assistive shoe designed to passively improve the biomechanics and rhythmicity of gait for people with foot drop. Read More

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http://dx.doi.org/10.1109/EMBC.2019.8857096DOI Listing

[Peroneal Nerve Palsy Management by Tibialis Posterior Muscle Transposition - Anatomical and Clinical Study].

Acta Chir Orthop Traumatol Cech 2019 ;86(6):419-422

Ústav anatomie Lékařské fakulty Univerzity Karlovy, Hradec Králové.

PURPOSE OF THE STUDY Transposition of tibialis posterior muscle ranks among the methods of dorsiflexion restoration in patients with peroneal nerve palsy. Even though this method is commonly used, anatomical variations are still encountered which make us modify the established procedures. The purpose of this study is to evaluate the functional outcomes of operated patients and based on the clinical experience to define by cadaver preparation the anatomical causes preventing the use of the standard transposition technique. Read More

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January 2020

Peroneal nerve palsy caused by a synovial cyst of the proximal tibiofibular joint: a report of two cases and review of the literature.

Pan Afr Med J 2019 29;34:115. Epub 2019 Oct 29.

Department of Trauma and Orthopaedics Surgery, Fattouma Bourguiba University Hospital, Monastir, Tunisia.

Synovial cyst of the proximal tibiofibular joint is a very rare condition, for which there is no consensus regarding treatment. Two macroscopic forms may be encountered: extraneural cysts and intraneural cysts. We present the cases of two patients who had synovial cysts of proximal tibiofibular joint that caused peroneal nerve palsy. Read More

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http://dx.doi.org/10.11604/pamj.2019.34.115.18339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945372PMC
January 2020

Concurrent Schwannoma and Intraneural Ganglion Cyst Involving Branches of the Common Peroneal Nerve.

World Neurosurg 2020 Mar 21;135:171-172. Epub 2019 Dec 21.

Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota, USA. Electronic address:

Benign peripheral nerve sheath tumors are well known to neurosurgeons and a relatively commonly seen pathology. Intraneural ganglion cysts, once thought to be rare and poorly understood, are increasingly recognized in clinical practice and better understood based on the advent of high-resolution imaging. There are few reports of different nerve lesions in the same anatomic location appearing concurrently. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.12.078DOI Listing

Outcomes with microsurgery of common peroneal nerve lesions.

J Plast Reconstr Aesthet Surg 2020 Jan 11;73(1):72-80. Epub 2019 Apr 11.

Orthopaedic Surgeon, Senior Consultant, University Hospital of Ioannina, Greece.

Objectives: The purpose of this retrospective study is to present our results with peroneal nerve lesions, to examine the relative significance of various factors, to assess their effect on outcome, and to establish guidelines of treatment for the microsurgical management of these difficult lesions.

Methods: Over a 33-year period, a total of 62 patients were treated at McGill University and the Microsurgical Research Center, Eastern Virginia Medical School. The clinical records of all patients treated for peroneal nerve lesions were reviewed for retrospective analysis. Read More

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http://dx.doi.org/10.1016/j.bjps.2019.02.031DOI Listing
January 2020

Compressive peroneal neuropathy by an intraneural ganglion cyst combined with L5 radiculopathy: A case report.

Medicine (Baltimore) 2019 Nov;98(44):e17865

Department of Physical Medicine and Rehabilitation, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.

Rationale: Most cases of foot drop are known to result from lower motor neuron pathologies, particularly lumbar radiculopathy and peripheral neuropathy, including common peroneal neuropathy. To improve the prognosis of foot drop, it is important to quickly and accurately diagnose the etiology and provide appropriate treatment.

Patient Concerns: A 65-year-old female patient with a history of L4-5 intervertebral disc herniation presented with right foot drop that had developed 1 month previously. Read More

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http://dx.doi.org/10.1097/MD.0000000000017865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946429PMC
November 2019
1 Read

Denoising of diffusion MRI improves peripheral nerve conspicuity and reproducibility.

J Magn Reson Imaging 2020 Apr 26;51(4):1128-1137. Epub 2019 Oct 26.

GE Healthcare, New York, New York, USA.

Background: Quantitative diffusion MRI is a promising technique for evaluating peripheral nerve integrity but low signal-to-noise ratio (SNR) can impede measurement accuracy.

Purpose: To evaluate principal component analysis (PCA) and generalized spherical deconvolution (genSD) denoising techniques to improve within-subject reproducibility and peripheral nerve conspicuity.

Study Type: Prospective. Read More

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http://dx.doi.org/10.1002/jmri.26965DOI Listing

Common Entrapment Neuropathies.

Semin Neurol 2019 10 22;39(5):549-559. Epub 2019 Oct 22.

Department of Neurology, American University of Beirut Medical Center, Riad El Solh, Beirut, Lebanon.

Entrapment neuropathies are defined as compression of peripheral nerves due to known or unknown causes. The high incidence and variety of presentations require a comprehensive knowledge of these conditions, especially in neurology and orthopedic surgery clinical practices. Detailed knowledge of topographic anatomy, clinical manifestations, and appropriate use of electrophysiological studies with selective addition of neuromuscular ultrasonography are needed to establish an early and accurate diagnosis to advice patients and provide them with a comprehensive treatment plan. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1693004
Publisher Site
http://dx.doi.org/10.1055/s-0039-1693004DOI Listing
October 2019
2 Reads

Acute bilateral drop foot as a complication of prolonged squatting due to haemorrhoid.

Ideggyogy Sz 2019 Sep;72(9-10):353-356

Bakirkoy Prof. Dr. Mazhar Osman Psychiatry and Neurology Research and Training Hospital, Istanbul, Turkey.

Drop foot is defined as difficulty of dorsiflexion of the foot and ankle due to weak anterior tibial, extensor hallucis longus and extensor digitorum longus muscles. Cauda equina syndrome, local peroneal nerve damage due to trauma, nerve entrapment, compartment syndrome and tumors are common etiologies. A 32-year-old male patient was applied with difficulty in dorsiflexion of both of his toes, feet and ankles after he had squatted in toilette for 6-7 hours (because of his haemorrhoid) after intense alcohol intake 2 weeks before. Read More

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http://dx.doi.org/10.18071/isz.72.0353DOI Listing
September 2019
1 Read
0.343 Impact Factor

In Reply.

Dtsch Arztebl Int 2019 09;116\\Server1\dgi_work\Aerzteblatt\2019\10_SCH_CALE\Dtsch_Arztebl_Int-116_33-34\(38):643-644

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http://dx.doi.org/10.3238/arztebl.2019.0643cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829160PMC
September 2019

High Prevalence of Asymptomatic Anterior Tarsal Tunnel Syndrome in Toddy Tappers of South India: A Case Series of 21 Participants.

J Neurosci Rural Pract 2019 Jul 9;10(3):506-510. Epub 2019 Oct 9.

Departments of Medicine, Kakatiya Medical College and MGM Hospital, Warangal, Telangana, India.

  Anterior tarsal tunnel syndrome (ATTS) is an uncommon entrapment neuropathy which occurs due to the compression of deep peroneal nerve under the inferior extensor retinaculum at the ankle. We observed a frequent occurrence of this syndrome in toddy palm tappers and hence, planned to study the association between the two.   We studied the prevalence of isolated deep peroneal neuropathy at the ankle among the asymptomatic toddy tappers enrolled over a period of 3 months. Read More

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http://dx.doi.org/10.1055/s-0039-1698290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785320PMC
July 2019
1 Read

Label Self-Advised Support Vector Machine (LSA-SVM)-Automated Classification of Foot Drop Rehabilitation Case Study.

Biosensors (Basel) 2019 Sep 27;9(4). Epub 2019 Sep 27.

Faculty of Engineering and Information Technology, University of Technology, Broadway, Sydney NSW 2007, Australia.

Stroke represents a major health problem in our society. One of the effects of stroke is foot drop. Foot drop (FD) is a weakness that occurs in specific muscles in the ankle and foot such as the anterior tibialis, gastrocnemius, plantaris and soleus muscles. Read More

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http://dx.doi.org/10.3390/bios9040114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6956170PMC
September 2019

Immediate effects of ankle eversion taping on gait ability of chronic stroke patients.

J Bodyw Mov Ther 2019 Jul 28;23(3):671-677. Epub 2018 Jun 28.

Department of Physical Therapy, College of Rehabilitation Sciences, Daegu University, Jillyang, Gyeongsan, Gyeongbuk, 712-714, Republic of Korea. Electronic address:

Objectives: The purpose of this study is to assess the immediate effects of applying ankle eversion taping using kinesiology tape in patients with foot drop after stroke.

Design: Randomized cross-over trial.

Method: In this study, fifteen subjects with stroke underwent three interventions in a random order. Read More

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http://dx.doi.org/10.1016/j.jbmt.2018.06.008DOI Listing
July 2019
1 Read

Evaluation of small nerve fiber dysfunction in type 2 diabetes.

Acta Neurol Scand 2020 Jan 9;141(1):38-46. Epub 2019 Oct 9.

Department of Hand Surgery, Skåne University Hospital, Malmö, Sweden.

Objectives: To assess potential correlations between intraepidermal nerve fiber densities (IENFD), graded with light microscopy, and clinical measures of peripheral neuropathy in elderly male subjects with normal glucose tolerance (NGT), impaired glucose tolerance (IGT), and type 2 diabetes (T2DM), respectively.

Materials And Methods: IENFD was assessed in thin sections of skin biopsies from distal leg in 86 men (71-77 years); 24 NGT, 15 IGT, and 47 T2DM. Biopsies were immunohistochemically stained for protein gene product (PGP) 9. Read More

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http://dx.doi.org/10.1111/ane.13171DOI Listing
January 2020
2 Reads

Long-Term Functional Outcome After Surgical Treatment of Peroneal Intraneural Ganglion Cyst.

World Neurosurg 2019 Dec 5;132:e217-e222. Epub 2019 Sep 5.

Plastic and Reconstructive Microsurgery, Careggi University Hospital, Florence, Italy.

Background: Intraneural ganglia are benign mucinous cystic formations that originate within the epineurium of peripheral nerves. Different treatments have been recommended, with an overall satisfactory outcome. In this paper, we aim to evaluate the long-term outcomes of surgical treatment of peroneal intraneural ganglia by reviewing our local institutional experience. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.08.195DOI Listing
December 2019
2 Reads

[Surgical Results of Lumbar Degenerative Disease with Foot Drop].

No Shinkei Geka 2019 Aug;47(8):851-857

Spinal Cord Treatment Center, Shinsuma General Hospital.

Drop foot is associated with various diseases, such as peripheral nerve disease, lumbar degenerative disease, metabolic disease, and endocrine disease. Among lumbar degenerative diseases, lumbar disc herniation and lumbar canal stenosis are most commonly reported. We report the surgical outcomes of patients with drop foot caused by lumbar degenerative diseases. Read More

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https://webview.isho.jp/journal/detail/abs/10.11477/mf.14362
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http://dx.doi.org/10.11477/mf.1436204036DOI Listing
August 2019
2 Reads

Intraneural Synovial Cyst of the Common Peroneal Nerve: An Unusual Cause of Foot Drop with Four-Year Follow-Up.

Case Rep Orthop 2019 5;2019:8045252. Epub 2019 Aug 5.

Center for Health Sciences, Oklahoma State University, USA.

In our case report, we describe a 55-year-old male patient with isolated foot drop due to an intraneural synovial ganglion. We successfully treated the lesion with decompression via epineurotomy combined with primary division of the recurrent articular branch of the common peroneal nerve (CPN). Compression neuropathies of the common peroneal nerve arise from a variety of causes. Read More

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https://www.hindawi.com/journals/crior/2019/8045252/
Publisher Site
http://dx.doi.org/10.1155/2019/8045252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6701310PMC
August 2019
2 Reads

Ulnar Neuropathy at Elbow in Patients With Type 2 Diabetes Mellitus.

J Clin Neurophysiol 2020 May;37(3):220-224

Department of Neurology, Cerrahpaşa School of Medicine, Istanbul University, Istanbul, Turkey.

Purpose: In diabetes mellitus (DM), upper extremity entrapment neuropathies are suggested to be a component of polyneuropathy (PNP). Our aim is to examine the presence of ulnar neuropathy at the elbow (UNE) and its relation to other findings including PNP in symptomatic and asymptomatic type-2 DM patients who were admitted for routine examinations.

Methods: The study included all cases referred for electromyography because of type-2 DM between November 2017 and May 2018. Read More

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http://dx.doi.org/10.1097/WNP.0000000000000629DOI Listing
May 2020
1 Read

Huangqi Guizhi Wuwu decoction for diabetic peripheral neuropathy: Protocol for a systematic review.

Medicine (Baltimore) 2019 Aug;98(31):e16696

Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, P.R. China.

Background: Diabetic peripheral neuropathy (DPN) is one of the most common causes of disability in diabetic population, and its pathogenesis is related to a variety of factors. There is currently no effective treatment for such chronic disease. Traditional Chinese medicine has a long clinical history for the prevention and treatment of diabetes and chronic complications, and it also shows certain advantages in the treatment of DPN. Read More

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http://dx.doi.org/10.1097/MD.0000000000016696DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709204PMC
August 2019
2 Reads
5.723 Impact Factor

Peroneal Nerve Injury Arising from Harvesting a Contralateral Hamstring Autograft for Cruciate Ligament Reconstruction: A Case Report.

JBJS Case Connect 2019 Jul-Sep;9(3):e0350

The Peripheral Nerve Injury Unit, Royal National Orthopaedic Hospital, London, United Kingdom.

Case: A 22-year-old man underwent a posterior cruciate ligament reconstruction following a sporting injury. Postoperatively, he developed a new foot drop on the hamstring harvest side that was contralateral to the ligamentous injury. On surgical exploration, a lesion in the peroneal nerve fascicles of the sciatic nerve, 20 cm from the fibula head, was neurolyzed with improvement in the foot drop. Read More

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http://dx.doi.org/10.2106/JBJS.CC.18.00350DOI Listing
June 2020
4 Reads

Ultrasound in the diagnosis and management of fibular mononeuropathy.

Muscle Nerve 2019 11 8;60(5):544-548. Epub 2019 Aug 8.

Neuromuscular Center, Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

Introduction: Ultrasound (US) evaluation of peripheral nerves is a noninvasive, cost-effective approach to diagnosing focal mononeuropathies and guiding surgical management. We used the intranerve ratio to evaluate for possible cut-off values in diagnosis of fibular mononeuropathies (FNs).

Methods: A retrospective analysis of FN confirmed by electrodiagnosis (EDx) was performed to identify intranerve ratio values between affected and unaffected limbs at the fibular head and popliteal fossa. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/mus.26652
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http://dx.doi.org/10.1002/mus.26652DOI Listing
November 2019
4 Reads

Electrophysiological Characterization of Neuropathy Complicating Type 1 Diabetes Mellitus.

J Diabetes Res 2019 2;2019:2435261. Epub 2019 Jul 2.

Department of Physiology, Faculty of Medicine, University of Khartoum, 11111, Sudan.

Diabetic peripheral neuropathy (DPN) involves sensory and motor nerves, resulting in demyelination as well as axonal degeneration. This study was conducted to describe the pattern of lower limb nerve involvement in children with type 1 diabetes mellitus (DM) based on the parameters of nerve conduction study (NCS). This cross-sectional study recruited 50 children with type 1 DM having mean disease duration of 4. Read More

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http://dx.doi.org/10.1155/2019/2435261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636586PMC
February 2020
1 Read

A Clinical and Electrophysiological Study of Peripheral Neuropathies in Predialysis and Dialysis Patients: Our Experience from South India.

J Assoc Physicians India 2018 Jun;66(6):31-37

Professor of Neurology, SVIMS, Tirupati, Andhra Pradesh.

Objective: To study the prevalence, clinical features, electrophysiological features and severity of peripheral neuropathy in chronic kidney disease (CKD) patients.

Methods: Between May 2015 and December 2016, 200 CKD patients and 25 controls were assessed prospectively.

Results: Prevalence of peripheral neuropathy in CKD patients was 50% based on clinical symptoms and 89% based on electrophysiological studies. Read More

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June 2018
4 Reads

Nerve entrapments related to muscle herniation.

Muscle Nerve 2019 10 1;60(4):428-433. Epub 2019 Aug 1.

Department of Neurology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York.

Background: Muscle herniation is a muscle protrusion through a fascial defect. It is a rarely reported cause of nerve entrapment.

Methods: We present a case of superficial fibular (peroneal) neuropathy associated with a fibularis (peroneus) brevis muscle herniation and a review of the literature on nerve entrapments secondary to muscle herniation unrelated to compartment syndrome. Read More

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http://dx.doi.org/10.1002/mus.26643DOI Listing
October 2019
1 Read

Muscle velocity recovery cycles in neurogenic muscles.

Clin Neurophysiol 2019 09 22;130(9):1520-1527. Epub 2019 Jun 22.

Department of Clinical Neurophysiology, Aarhus University Hospital, Denmark; Department of Clinical Medicine, Aarhus University, Denmark. Electronic address:

Objective: To examine muscle membrane properties in neurogenic muscles using Muscle Velocity Recovery Cycles (MVRCs).

Methods: Forty-seven patients referred to Nerve Conduction Studies (NCS) and Electromyography (EMG) for peroneal nerve entrapment neuropathy were prospectively included. The patients were categorized as peroneal nerve entrapment neuropathy across knee (n = 22), L5-radiculapathy (n = 10), normal NCS/EMG (n = 9) and other disorders (n = 6) using NCS/EMG and neuroimaging results. Read More

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http://dx.doi.org/10.1016/j.clinph.2019.05.030DOI Listing
September 2019
1 Read

The Interdisciplinary Management of Foot Drop.

Dtsch Arztebl Int 2019 May;116(20):347-354

Clinic for Neurosurgery, University Medical Center Knappschaftskrankenhaus Bochum, Bochum, Germany; Department of Surgery, Plastic Surgery and Hand Surgery, Pauwelsklinik Aachen, Aachen, Germany; Department of Neurology, University Hospital Münster, Münster, Germany; Department of Orthopedic and Trauma Surgery, University Medical Center Knappschaftskrankenhaus Bochum, Bochum, Germany.

Background: Foot drop can be caused by a variety of diseases and injuries. Although it is a common condition, its overall incidence has not been reported to date. Foot drop markedly restricts the everyday activities of persons suffering from it. Read More

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http://dx.doi.org/10.3238/arztebl.2019.0347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637663PMC
May 2019
3 Reads

Deep peroneal nerve palsy after opening wedge high tibial osteotomy: A case report.

Medicine (Baltimore) 2019 Jul;98(27):e16253

Department of Physical Medicine & Rehabilitation, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.

Rationale: Peroneal nerve injury is one of the major complications that may occur after closing wedge high tibial osteotomy (CWHTO). In contrast, the reduced risk of the peroneal nerve injury has been considered as one of the advantages of opening wedge HTO (OWHTO).

Patient Concerns: A 61-year-old male who underwent OWHTO showed a dropped big toe immediately after surgery. Read More

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http://dx.doi.org/10.1097/MD.0000000000016253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635290PMC
July 2019
4 Reads

Thread common peroneal nerve release-a cadaveric validation study.

Acta Neurochir (Wien) 2019 09 4;161(9):1931-1936. Epub 2019 Jul 4.

Department of Neurosurgery, Stanford University, 300 Pasteur Dr, Palo Alto, CA, 94304, USA.

Objective: To determine if the thread release technique can be applied to common peroneal nerve entrapment at the fibular neck.

Methods: The thread common peroneal nerve release was performed on 15 fresh frozen cadaveric lower extremity specimens. All procedures were performed under ultrasound guidance and immediately underwent post-procedural gross anatomic inspection for completeness of decompression and presence or absence of iatrogenic neurovascular injury. Read More

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http://dx.doi.org/10.1007/s00701-019-03998-yDOI Listing
September 2019
2 Reads

Gliosarcoma in a Young Filipino Woman: A Case Report and Review of the Literature.

Am J Case Rep 2019 Jun 27;20:914-919. Epub 2019 Jun 27.

Division of Neuropathology, University of Alberta, Walter Mackenzie Health Sciences Center, Edmonton, Alberta, Canada.

BACKGROUND Gliosarcoma (GS) is a rare variant of glioblastoma (GBM), which is typically seen in patients age 40-60 years and located in the supratentorial region. We present an unusual case of GS in a young patient with an unusual presentation, which eventually led to the finding of this neoplasm. CASE REPORT Our patient was a 38-year-old woman originally from the Philippines who was transferred to our institution with an isolated left foot drop that developed over the course of several months. Read More

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http://dx.doi.org/10.12659/AJCR.916020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613492PMC
June 2019
5 Reads

Long-term outcomes in a 25-year-old female affected with lipin-1 deficiency.

JIMD Rep 2019 Mar 14;46(1):4-10. Epub 2019 Mar 14.

University College Dublin Dublin Ireland.

Lipin-1 is a phosphatidic acid phosphohydrolase (EC 3.1.3. Read More

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http://dx.doi.org/10.1002/jmd2.12016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498837PMC
March 2019
6 Reads

Bilateral nerve conduction studies in the evaluation of distal symmetric polyneuropathy.

Muscle Nerve 2019 09 2;60(3):305-307. Epub 2019 Jul 2.

Department of Neurology, University of Michigan, 1324 Taubman Center SPC 5322, 1500 East Medical Center Drive, Ann Arbor, Michigan, 48109-5322, USA.

Introduction: Nerve conduction studies are used to aid in the diagnosis of distal symmetric polyneuropathy (DSP). It is unclear whether bilateral lower extremity nerve conduction studies (NCS) are needed when evaluating for suspected DSP.

Methods: We retrospectively analyzed NCS from patients who presented to the University of Michigan electromyography laboratory between July 1, 2016 and December 31, 2017 with symptoms of DSP to assess agreement and correlation between left and right lower extremity NCS parameters. Read More

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http://dx.doi.org/10.1002/mus.26616DOI Listing
September 2019
3 Reads

Mutations in C1orf194, encoding a calcium regulator, cause dominant Charcot-Marie-Tooth disease.

Brain 2019 08;142(8):2215-2229

Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, P.R. China.

Charcot-Marie-Tooth disease is a hereditary motor and sensory neuropathy exhibiting great clinical and genetic heterogeneity. Here, the identification of two heterozygous missense mutations in the C1orf194 gene at 1p21.2-p13. Read More

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http://dx.doi.org/10.1093/brain/awz151DOI Listing
August 2019
10 Reads
9.196 Impact Factor

Early nerve fibre regeneration in individuals with type 1 diabetes after simultaneous pancreas and kidney transplantation.

Diabetologia 2019 08 7;62(8):1478-1487. Epub 2019 Jun 7.

Institute of Cardiovascular Sciences, University of Manchester and Central Manchester NHS Foundation Trust, Core Technology Facility, Grafton Street, Manchester, M13 9NT, UK.

Aims/hypothesis: The study aimed to assess the impact on neuropathy of simultaneous pancreas and kidney transplantation (SPK) in individuals with type 1 diabetes.

Methods: This longitudinal observational study examined neuropathic symptoms, deficits, quantitative sensory testing, neurophysiology, corneal confocal microscopy and skin biopsy results in 32 healthy (non-diabetic) control participants, 29 individuals with type 1 diabetes and severe diabetic peripheral neuropathy [DPN] and 36 individuals with type 1 diabetes after SPK.

Results: Following SPK, HbA, eGFR, triacylglycerols and HDL improved significantly (all p < 0. Read More

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http://dx.doi.org/10.1007/s00125-019-4897-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6647173PMC
August 2019
11 Reads

[Clinical trials of treatment of post-stroke foot drop by fire-needling plus stuck-needle-stretching].

Zhen Ci Yan Jiu 2019 May;44(5):367-72

Graduate School of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510006, China.

Objective: To compare the therapeutic effect of fire-needling plus stuck-needle-stretching and conventional acupuncture for post-stroke foot drop, so as to provide a reference foundation for optimizing clinical treatment regimen.

Methods: A total of 60 patients with post-stroke foot drop were equally randomized into a treatment group and a control group. In the treatment group, fire-needling plus stuck-needle-stretching was applied to acupoint pairs Jiexi (ST41)-Taichong (LR3), Xiajuxu (ST39)-ST41, Fenglong (ST40)-ST39, shangjuxu (ST37)-ST40, Zusanli (ST36)-ST37, Dubi (ST35)-ST36, Xuanzhong (GB39)-Qiuxu (GB40) on the affected side, and Chengshan (BL57) and Ashi points were swiftly pricked with red-hot filiform needle without needle retaining. Read More

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http://dx.doi.org/10.13702/j.1000-0607.180725DOI Listing
May 2019
13 Reads

Association of Serum Cholesterol Levels With Peripheral Nerve Damage in Patients With Type 2 Diabetes.

JAMA Netw Open 2019 05 3;2(5):e194798. Epub 2019 May 3.

Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.

Importance: Lowering serum cholesterol levels is a well-established treatment for dyslipidemia in patients with type 2 diabetes (T2D). However, nerve lesions in patients with T2D increase with lower serum cholesterol levels, suggesting that lowering serum cholesterol levels is associated with diabetic polyneuropathy (DPN) in patients with T2D.

Objective: To investigate whether there is an association between serum cholesterol levels and peripheral nerve lesions in patients with T2D with and without DPN. Read More

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http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
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http://dx.doi.org/10.1001/jamanetworkopen.2019.4798DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547108PMC
May 2019
8 Reads

Electrophysiological findings in immune checkpoint inhibitor-related peripheral neuropathy.

Clin Neurophysiol 2019 08 9;130(8):1440-1445. Epub 2019 May 9.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Objective: To report the electrodiagnostic features of immune checkpoint inhibitor (ICI)-related neuropathy.

Methods: We retrospectively reviewed clinical presentations and electrodiagnostic features of 23 patients studied after receiving immune checkpoint inhibitors (ICIs). The presentations for electrodiagnostic evaluation included an acute neuropathy or neuromuscular junction disorder. Read More

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http://dx.doi.org/10.1016/j.clinph.2019.03.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628895PMC
August 2019
11 Reads

Surplus value of implanted peroneal functional electrical stimulation over ankle-foot orthosis for gait adaptability in people with foot drop after stroke.

Gait Posture 2019 06 3;71:157-162. Epub 2019 May 3.

Department of Rehabilitation, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands. Electronic address:

Background: Implanted peroneal functional electrical stimulation (FES) is an effective alternative treatment to ankle-foot orthosis (AFO) in people with drop foot after stroke. With FES no constraints on ankle mobility are imposed which might particularly be exploited in challenging walking environments that require adaptations of the gait pattern to environmental disturbances.

Research Question: Is gait adaptability, by means of the capacity to avoid sudden obstacles while walking on a treadmill, superior with implanted FES compared to AFO in people with drop foot after stroke?

Methods: A 4-channel peroneal nerve stimulator (ActiGait®) was implanted in 22 persons with stroke (>6 months) who regularly used an AFO. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09666362183135
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http://dx.doi.org/10.1016/j.gaitpost.2019.04.020DOI Listing
June 2019
9 Reads

Clinical and neurophysiological findings in patients with hereditary neuropathy with liability to pressure palsy and chromosome 17p11.2 deletion.

Neurologia 2019 Apr 29. Epub 2019 Apr 29.

Servicio de Neurofisiología Clínica, Complejo Hospitalario de Navarra, Pamplona, España.

Introduction: Hereditary neuropathy with liability to pressure palsy (HNPP) is an autosomal dominant disorder, typically presenting with recurrent episodes of mononeuropathy in nerves susceptible to compression, with similar neurophysiological characteristics. However, other clinical and neurophysiological presentations have been reported.

Methods: We retrospectively analysed the clinical and neurophysiological characteristics of 20 patients with genetically confirmed HNPP. Read More

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http://dx.doi.org/10.1016/j.nrl.2019.02.005DOI Listing
April 2019
8 Reads

Design and Workspace Analysis of a Parallel Ankle Rehabilitation Robot (PARR).

J Healthc Eng 2019 14;2019:4164790. Epub 2019 Mar 14.

College of Mechanical Engineering and Applied Electronics Technology, Beijing University of Technology, Beijing, China.

The ankle rehabilitation robot is essential equipment for patients with foot drop and talipes valgus to make up deficiencies of the manual rehabilitation training and reduce the workload of rehabilitation physicians. A parallel ankle rehabilitation robot (PARR) was developed which had three rotational degrees of freedom around a virtual stationary center for the ankle joint. The center of the ankle should be coincided with the virtual stationary center during the rehabilitation process. Read More

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https://www.hindawi.com/journals/jhe/2019/4164790/
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http://dx.doi.org/10.1155/2019/4164790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437750PMC
May 2020
22 Reads

The clinical- and cost-effectiveness of functional electrical stimulation and ankle-foot orthoses for foot drop in Multiple Sclerosis: a multicentre randomized trial.

Clin Rehabil 2019 Jul 11;33(7):1150-1162. Epub 2019 Apr 11.

1 Douglas Grant Rehabilitation Centre, Ayrshire Central Hospital, NHS Ayrshire & Arran, Irvine, UK.

Objective: To compare the clinical- and cost-effectiveness of ankle-foot orthoses (AFOs) and functional electrical stimulation (FES) over 12 months in people with Multiple Sclerosis with foot drop.

Design: Multicentre, powered, non-blinded, randomized trial.

Setting: Seven Multiple Sclerosis outpatient centres across Scotland. Read More

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http://dx.doi.org/10.1177/0269215519842254DOI Listing
July 2019
8 Reads