1,703 results match your criteria Peroneal Mononeuropathy


Foot Drop, Hindfoot Varus, and Tibialis Posterior Tendon Transfer in Cerebral Palsy.

Orthop Clin North Am 2022 Jul 27;53(3):311-317. Epub 2022 May 27.

Department of Orthopaedic Surgery, University of California Davis, 4860 Y Street, Suite 3800, Sacramento, CA, USA; Department of Orthopaedic Surgery, Shriners Children's Hospital Northern California, 2425 Stockton Boulevard, Sacramento, CA 95817, USA. Electronic address:

The transfer of the tibialis posterior tendon has been used to correct hindfoot varus and dorsiflexion weakness in cerebral palsy. It is expendable, has a favorable direction for dorsiflexion and eversion posterior to the tibia, and is the source of hindfoot varus in most cases. However, the foot and ankle must be flexible without skeletal deformity. Read More

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[Systematic review and Meta-analysis of efficacy and safety of Shuxuetong Injection in treatment of diabetic peripheral neuropathy].

Zhongguo Zhong Yao Za Zhi 2022 Jun;47(11):3088-3094

Beijing Hospital of Traditional Chinese Medicine, Capital Medical University Beijing 100010, China.

The present study evaluated the efficacy and safety of Shuxuetong Injection in the treatment of diabetic peripheral neuropathy(DPN). PubMed, Cochrane Library, EMbase, CNKI, VIP, SinoMed, and Wanfang were searched for randomized controlled trials(RCTs) of Shuxuetong Injection in the treatment of DPN from database inception to July 18, 2021. Literature screening was carried out according to the inclusion and exclusion criteria, and the required information was extracted. Read More

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CORRELATION BETWEEN QUALITY OF LIFE AND THE CLINICAL RESULTS OF PATIENTS WITH LEPROSY WITH DROP FOOT AFTER TENDON TRANSFER.

Acta Ortop Bras 2022 23;30(3):e244354. Epub 2022 May 23.

Universidade Federal do Rio de Janeiro, Faculty of Medicine, Rio de Janeiro, RJ, Brazil.

Objective: To evaluate the functional results of surgically correcting drop foot in patients with leprosy and compare their SALSA, Social Participation, and AOFAS score.

Methods: Overall, 22 patients were subjected to posterior tibial tendon transfer via the subcutaneous route to the foot dorsum with an average follow-up of 56 months (min 12, max 70). In our sample, 15 of the enrolled patients were men and seven, women, aged between 20 and 73 years old who were operated on from January 2014 to December 2017. Read More

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Spatiotemporal, kinematic and kinetic assessment of the effects of a foot drop stimulator for home-based rehabilitation of patients with chronic stroke: a randomized clinical trial.

J Neuroeng Rehabil 2022 Jun 7;19(1):56. Epub 2022 Jun 7.

Department of Rehabilitation Medicine, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, China.

Background: Gait disability affects the daily lives of patients with stroke in both home and community settings. An abnormal foot-ankle position can cause instability on the supporting surface and negatively affect gait. Our research team explored the ability of a portable peroneal nerve-targeting electrical stimulator to improve gait ability by adjusting the foot-ankle position during walking in patients with chronic stroke undergoing home-based rehabilitation. Read More

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Clinical and neurophysiological findings in patients with hereditary neuropathy with liability to pressure palsy and chromosome 17p11.2 deletion.

Neurologia (Engl Ed) 2022 May 24;37(4):243-249. Epub 2021 Apr 24.

Servicio de Neurofisiología Clínica, Complejo Hospitalario de Navarra, Pamplona, Spain.

Introduction: Hereditary neuropathy with liability to pressure palsy (HNPP) is an autosomal dominant disorder, typically presenting with recurrent episodes of mononeuropathy in nerves susceptible to compression, with similar neurophysiological characteristics. However, other clinical and neurophysiological presentations have been reported.

Methods: We retrospectively analysed the clinical and neurophysiological characteristics of 20 patients with genetically confirmed HNPP. Read More

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Performance Analysis of Conventional Machine Learning Algorithms for Diabetic Sensorimotor Polyneuropathy Severity Classification Using Nerve Conduction Studies.

Comput Intell Neurosci 2022 25;2022:9690940. Epub 2022 Apr 25.

Department of Physics and Electronics, Dr. Ram Manohar Lohia Avadh University, Ayodhya 224001, India.

Background: Diabetic sensorimotor polyneuropathy (DSPN) is a major form of complication that arises in long-term diabetic patients. Even though the application of machine learning (ML) in disease diagnosis is very common and well-established in the field of research, its application in DSPN diagnosis using nerve conduction studies (NCS), is very limited in the existing literature.

Method: In this study, the NCS data were collected from the Diabetes Control and Complications Trial (DCCT) and its follow-up Epidemiology of Diabetes Interventions and Complications (EDIC) clinical trials. Read More

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Sciatic nerve microvascular permeability in type 2 diabetes decreased in patients with neuropathy.

Ann Clin Transl Neurol 2022 Jun 30;9(6):830-840. Epub 2022 Apr 30.

Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany.

Objectives: Clinical and histological studies have found evidence that nerve ischemia is a major contributor to diabetic neuropathy (DN) in type 2 diabetes (T2D). The aim of this study was to investigate peripheral nerve microvascular permeability using dynamic contrast enhanced (DCE) magnetic resonance neurography (MRN) to analyze potential correlations with clinical, electrophysiological, and demographic data.

Methods: Sixty-five patients (35/30 with/without DN) and 10 controls matched for age and body mass index (BMI) underwent DCE MRN of the distal sciatic nerve with an axial T1-weighted sequence. Read More

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Eosinophilic Granulomatosis with Polyangiitis that was Difficult to Distinguish from Peroneal Nerve Palsy and Lumbar Disc Herniation: A Case Report.

J Orthop Case Rep 2021 Jun;11(6):44-48

Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5, Zaifu-cho, Hirosaki 0368562, Japan.

Introduction: Eosinophilic granulomatosis with polyangiitis (EGPA) patients with mononeuropathy multiplex often visit orthopedic clinics; however, orthopedic surgeons have limited experience in diagnosing EGPA because of its rarity. We report a case of EGPA that required 1 month to confirm the diagnosis.

Case Report: A 48-year-old woman presented with acute onset numbness in the right lower extremity. Read More

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A 17-year-old boy who presented with acute mononeuropathy was found to have Type 1 diabetes.

Paediatr Int Child Health 2022 Apr 7:1-3. Epub 2022 Apr 7.

Departments of Pediatric Endocrinology, Trakya University Faculty of Medicine, Edirne, Turkey.

Diabetic neuropathy in children and adolescents with Type 1 diabetes mellitus is rare and is usually subclinical and a complication of the late diabetes period. A 17-year-old boy admitted with a right foot drop of sudden onset was diagnosed with peroneal nerve palsy. He had had osmotic polyuria, polydipsia and weight loss for the past 2 months; his blood glucose was 25 mmol/L (<7. Read More

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Surgical Treatment of Foot Drop: Pathophysiology and Tendon Transfers for Restoration of Motor Function.

Orthop Clin North Am 2022 Apr 7;53(2):235-245. Epub 2022 Mar 7.

Department of Orthopedic Surgery, Washington University School of Medicine, Campus Box 8233, 660 South Euclid Avenue, Saint Louis, Missouri 63110, USA.

Foot drop is a common condition that may impact physical function and health-related quality of life. A detailed clinical history and physical examination are critical components of the initial evaluation of patients presenting with foot drop. Patients with refractory foot drop without spontaneous recovery of motor deficits, delayed presentation greater than 12 months from injury, or neural lesions that are not amenable to or have failed nerve reconstruction may be candidates for tendon transfers to restore active ankle dorsiflexion. Read More

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Surgical Treatment of Foot Drop: Patient Evaluation and Peripheral Nerve Treatment Options.

Orthop Clin North Am 2022 Apr 5;53(2):223-234. Epub 2022 Mar 5.

Department of Orthopaedic Surgery, Washington University School of Medicine, Campus Box 8233, 660 South Euclid Avenue, Saint Louis, Missouri 63110, USA.

Foot drop is a common clinical condition which may substantially impact physical function and health-related quality of life. The etiologies of foot drop are diverse and a detailed history and physical examination are essential in understanding the underlying pathophysiology and capacity for spontaneous recovery. Patients presenting with acute foot drop or those without significant spontaneous recovery of motor deficits may be candidates for surgical intervention. Read More

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Development of a New Ankle Joint Hybrid Assistive Limb.

Medicina (Kaunas) 2022 Mar 7;58(3). Epub 2022 Mar 7.

Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba 305-8575, Ibaraki, Japan.

Foot and ankle disabilities (foot drop) due to common peroneal nerve palsy and stroke negatively affect patients' ambulation and activities of daily living. We developed a novel robotics ankle hybrid assistive limb (HAL) for patients with foot drop due to common peroneal nerve palsy or stroke. The ankle HAL is a wearable exoskeleton-type robot that is used to train plantar and dorsiflexion and for voluntary assistive training of the ankle joint of patients with palsy using an actuator, which is placed on the lateral side of the ankle joint and detects bioelectrical signals from the tibialis anterior (TA) and gastrocnemius muscles. Read More

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Immediate Effect of Lower-Leg Kinesio Taping on Ankle Dorsiflexion and Gait Parameters in Chronic Stroke with Foot Drop.

J Stroke Cerebrovasc Dis 2022 May 4;31(5):106425. Epub 2022 Mar 4.

Department of Physical Therapy, Graduate School, College of Health Sciences, Kyungnam University, Changwon, Republic of Korea. Electronic address:

Objective: Kinesio taping (KT) and proprioceptive neuromuscular facilitation (PNF) are interventions mainly used in clinical settings to improve gait after stroke. Lower-leg KT using the concept of PNF (PNF-KT) has been shown to enhance the recovery of gait speed in patients with stroke. But, the effect of PNF-KT on the ankle movement and gait parameters in stroke patients is unclear. Read More

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Soft Tissue Management and Tibialis Posterior Tendon Transfer in Acute Correction for Neglected Drop Foot Deformity.

J Foot Ankle Surg 2022 May-Jun;61(3):615-620. Epub 2021 Oct 27.

Surgeon, Professor, Department of Hand and Reconstructive Microsurgery, Yeniyyüzyıl University Gaziosmanpaşa Hospital, İstanbul, Türkiye.

Acute correction of rigid drop foot deformity can be problematic due to the skin defect that may occur in the medial part of the ankle. The purpose of this study is to present an innovative solution for this problem. We hypothesized that acute correction for rigid ankle contractures without arthrosis might be possible if the medial skin defect could be closed. Read More

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Correlation Analysis and Intervention Study on Disturbance of Lipid Metabolism and Diabetic Peripheral Neuropathy.

Comput Math Methods Med 2022 22;2022:2579692. Epub 2022 Feb 22.

Department of Endocrinology, The First People's Hospital of Jiangxia District, Wuhan City, 430200 Hubei Province, China.

Objective: To explore the significance and clinical value of dynamic monitoring of lipid metabolism indexes in patients with diabetic peridiabetic lesions.

Methods: A total of 192 patients with type 2 diabetes (T2DM) treated in our hospital from October 2019 to July 2021 were divided into two groups according to whether they were complicated with peripheral neuropathy (DPN). The patients in the observation group were randomly assigned into group A ( = 45) and group B ( = 45) according to the method of random number table. Read More

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Isolating the Superficial Peroneal Nerve Motor Branch to the Peroneus Longus Muscle with Concentric Stimulation during Diagnostic Motor Nerve Biopsy.

Neurodiagn J 2022 Mar 28;62(1):26-36. Epub 2022 Feb 28.

Department of Neurological Surgery Lenox Hill Hospital/Donald and Barbara Zucker School of Medicine at Hofstra, New York, New York.

Motor nerve biopsies are performed in the workup of neuropathies of unknown origin when motor neuron disease is suspected. Biopsy of a motor branch of the superficial peroneal nerve innervating the peroneus longus muscle has been described as a convenient alternative to other commonly biopsied motor nerves. To date, neuromonitoring techniques have not been described for this procedure. Read More

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Ultrasound of Small Nerves.

Ultraschall Med 2022 Feb 8;43(1):12-33. Epub 2022 Feb 8.

Department of Radiology, Innsbruck Medical University Innsbruck, Austria.

Nerve ultrasound has become an integral part of the diagnostic workup of peripheral neuropathies. Especially in the examination of small nerves, ultrasound provides superior image quality by using high frequency transducers. For a selection of small nerves, this article summarizes the local anatomy and common pathologies and offers simple instructions for determining their location with ultrasound including some cases with pathologies. Read More

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February 2022

The association between physical activity time and neuropathy in longstanding type 1 diabetes: A cross-sectional analysis of the Canadian study of longevity in type 1 diabetes.

J Diabetes Complications 2022 03 31;36(3):108134. Epub 2022 Jan 31.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada; Division of Endocrinology and Metabolism, Department of Medicine, University of Toronto. Toronto, Ontario, Canada.

Aim: Physical activity (PA) is recommended to improve glycemic control in T1D; however, the effect of PA on distal symmetric polyneuropathy (DSPN) and cardiac autonomic function in longstanding T1D is unknown.

Methods: Data from 75 participants were collected as part of the Canadian Study of Longevity in T1D. Participants completed a physical exam, medical history, extensive complications phenotyping and reported their daily PA from the preceding 12-months. Read More

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Acute Peroneal Neuropathy and Foot Drop in Two Adolescent Female Athletes with New-Onset Diabetes.

Curr Sports Med Rep 2022 Feb;21(2):39-41

Division of Pediatric Endocrinology, Department of Pediatrics, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN.

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February 2022

Utilization of Intraoperative Biphasic Waveform Nerve Stimulator for Performing Nerve Transfer for the Treatment of Drop Foot: Addendum to Evaluation and Treatment of Foot Drop Using Nerve Transfer Techniques.

Clin Podiatr Med Surg 2021 Jan 16;38(1S):e1-e6. Epub 2021 Jun 16.

Adults & Pediatric Ilizarov Limb Deformity Correction, Peripheral Nerve Reconstructive Microsurgery, American Microsurgical Orthoplastic Society, Department of Surgery, Amita Saint Joseph Hospital, Laboure Outpatient Clinic, 2913 North Commonwealth Avenue, Chicago, IL 60567, USA.

This article provides the surgeon with a detailed technique guide using an alternating current biphasic waveform intraoperative nerve stimulator, such as the Checkpoint surgical nerve stimulator. The Checkpoint surgical nerve stimulator is an intraoperative hand-held biphasic device that is essential when performing nerve transfer techniques for the treatment of drop foot. This specific device provides the surgeon safe, accurate, reproducible, and continuous stimulation without fatigue or a decreased response to the nerve. Read More

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January 2021

Investigating the effects of conventional thermoplastic ankle-foot and the neoprene ankle-foot orthoses on the kinetics and kinematics of gait in people with foot drop following traumatic injury of the peroneal nerve: A pilot study.

Foot (Edinb) 2022 Mar 30;50:101898. Epub 2021 Dec 30.

Division of Physical Medicine & Rehabilitation, Department of Medicine, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, AB T6G 2G3, Canada. Electronic address:

Background: Adopting compensatory walking mechanisms by people with foot drop due to traumatic injury of the peroneal nerve costs altered gait kinetics and kinematics. Therefore, orthoses are generally recommended to minimize the deployment of compensatory gait mechanisms.

Objectives: To investigate the immediate effects of a low-cost, Neoprene Ankle-Foot Orthosis (NAFO) and the thermoplastic ankle-foot orthosis (AFO) with the shoe-only condition on kinematics and kinetics of gait of people with foot drop following peroneal nerve traumatic injury. Read More

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Childhood focal compressive mononeuropathies during the COVID-19 pandemic in Buenos Aires, Argentina.

Muscle Nerve 2022 05 21;65(5):590-593. Epub 2022 Feb 21.

Neurology Department, FLENI, Buenos Aires, Argentina.

Introduction/aims: Focal peripheral neuropathies are infrequently seen in pediatric patients. The COVID-19 pandemic has disrupted normal life for many people, including complete lockdowns and school closing for long periods of time in many countries, which prompted children to stay at home. Our aim is to assess whether there has been an increased incidence of focal compressive peripheral neuropathies in the pediatric population during COVID-19-associated lockdown. Read More

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Vitamin D and Nerve Conduction In Pediatric Type-1 Diabetes Mellitus.

Brain Dev 2022 May 15;44(5):336-342. Epub 2022 Jan 15.

Mardin State Hospital, Pediatric Neurology, Mardin, Turkey.

Introduction: The aim of this study is to investigate a possible association between vitamin D deficiency and diabetic peripheral neuropathy in pediatric patients with type 1 diabetes mellitus.

Materials-methods: Twenty-nine patients with type 1 diabetes mellitus and 19 healthy controls were included to the study. All individuals were evaluated for diabetic peripheral neuropathy with nerve conduction studies. Read More

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Traumatic Peroneal Nerve Injuries: A Systematic Review.

JBJS Rev 2022 01 12;10(1). Epub 2022 Jan 12.

University of Kansas School of Medicine, Kansas City, Kansas.

Background: The common peroneal nerve (CPN) is the most commonly injured peripheral nerve of the lower extremity in patients with trauma. Traumatic CPN injuries have historically been associated with relatively poor outcomes and patient satisfaction, although improved surgical technique and novel procedures appear to improve outcomes. Given the variety of underlying injury modalities, treatment options, and prognostic variables, we sought to evaluate and summarize the current literature on traumatic CPN injuries and to provide recommendations from an analysis of the included studies for treatment and future research. Read More

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January 2022

Trigger of Type 2 Lepra reaction with acute foot drop following Covid-19 vaccination.

J Eur Acad Dermatol Venereol 2022 05 25;36(5):e334-e335. Epub 2022 Jan 25.

Department of Dermatology, Institute of Medical Sciences and SUM Hospital, S 'O'A University, Bhubaneswar, India.

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Prevalence of peripheral neuropathy and associated risk factors in children with type 1 diabetes.

Prim Care Diabetes 2022 04 5;16(2):287-292. Epub 2022 Jan 5.

Pediatric Neurology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address:

Aim: To detect the prevalence of diabetic polyneuropathy (DPN) in children with type 1 diabetes (T1D) and to identify associated the risk factors.

Methods: This cross-sectional study evaluated children aged between 2 and 16y with T1D for ≥2 y. Detailed neurological examination, neuropathy symptom score, and nerve conduction studies were done in all children to assess nerve dysfunction. Read More

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Clinical and pathological study of SORD-related distal motor neuropathy caused by novel compound heterozygous mutations in a Chinese patient.

Clin Neurol Neurosurg 2022 02 31;213:107118. Epub 2021 Dec 31.

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China; China National Clinical Research Center for Neurological Diseases, Beijing, China.

Sorbitol dehydrogenase (SORD) has been identified as the causative gene of autosomal recessive distal hereditary motor neuropathies (dHMN). Here, we describe a 25-year-old woman who presented with progressive weakness of both lower limbs for the previous 10 years. Electrophysiological results suggested only a reduction in the compound muscle action potential (CMAP) amplitude of both the tibial and left deep peroneal nerves and neurogenic changes in needle EMG. Read More

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February 2022

Exercise and Neuropathy: Systematic Review with Meta-Analysis.

Sports Med 2022 05 29;52(5):1043-1065. Epub 2021 Dec 29.

Department of Sport, Exercise and Health, University of Basel, Grosse Allee 6, 4052, Basel, Switzerland.

Introduction: Peripheral neuropathies are a prevalent, heterogeneous group of diseases of the peripheral nervous system. Symptoms are often debilitating, difficult to treat, and usually become chronic. Not only do they diminish patients' quality of life, but they can also affect medical therapy and lead to complications. Read More

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Clinical and electrophysiological characteristics of neuropathic pain in leprosy patients: A prospective cross-sectional study.

Indian J Dermatol Venereol Leprol 2021 Oct 20:1-4. Epub 2021 Oct 20.

Department of Dermatology, Federal University of Para, Belém, Pará, Brazil.

Introduction: Neuropathic pain is a common and disabling late complication of leprosy. We investigated the clinical and electrophysiological characteristics of neuropathic pain in leprosy patients by evaluating nerve conduction, sympathetic skin response (SSR) and A-waves.

Methods: Twenty one leprosy patients with neuropathic pain validated by the Douleur Neuropathique en 4 (DN4)Questionnaire were selected for study. Read More

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October 2021

Heart rate-corrected QT interval: A novel diagnostic biomarker for diabetic peripheral neuropathy.

J Diabetes Investig 2022 May 6;13(5):850-857. Epub 2022 Jan 6.

Department of Endocrinology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Aims/introduction: To explore the relationship between heart rate-corrected QT (QTc) interval and diabetic peripheral neuropathy (DPN), and whether QTc interval has diagnostic utility for DPN beyond nerve conduction velocity.

Materials And Methods: A total of 965 patients with diabetes, including 473 patients with DPN and 492 patients without DPN, underwent standard 12-lead electrocardiography and detailed assessments of peripheral neuropathy.

Results: Patients with DPN had longer QTc intervals than those without. Read More

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