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Wiad Lek 2022 ;75(5 pt 1):1095-1099

BOGOMOLETS NATIONAL MEDICAL UNIVERSITY, KYIV, UKRAINE.

Objective: The aim: To search for new and improvement of known methods of diagnosis and surgical treatment of atypical forms of acute appendicitis.

Patients And Methods: Materials and methods: There were analyzed the results of diagnosis and surgical treatment of 852 patients with atypical course of acute appendicitis, which amounted to 25.3% of the total number of patients in this category. Read More

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 May;47(5):639-649

Department of Nephrology, Third Xiangya Hospital, Central South University, Changsha 410013, China.

Objectives: Peritoneal dialysis associated peritonitis (PDAP), one of the most common complications of peritoneal dialysis, is generally believed as an important factor causing technique failure and increasing hospital admission and fatality rate in peritoneal dialysis patients. Moreover, the prevention and treatment for PDAP have always been considered as an important link in clinical peritoneal dialysis. Thus, the study is performed to investigate the impact of climate factors on the incidence and prognosis of single-center PDAP in Hunan Province, China, which can provide a clinical basis for the prevention and treatment strategy for PDAP. Read More

Klin Lab Diagn 2022 Jun;67(6):374-379

Kirov State Medical University.

Over the past decade, the frequency of abdominal delivery in Russia has increased to an average of 25 %. The widespread use of abdominal delivery has not been without an increase in the incidence of complications. Among them is an infectious complication of a surgical obstetric wound (ICD O86. Read More

SAGE Open Med Case Rep 2022 16;10:2050313X221105922. Epub 2022 Jun 16.

Department of Obstetrics and Gynaecology, Faculty of Postgraduate Medicine, Khesar Gyalpo University of Medical Sciences of Bhutan, Thimphu, Bhutan.

With increasing rate of cesarean section in Bhutan, the complications are expected to rise. Uterine scar dehiscence is one of the immediate complications of cesarean section, which has high morbidity and mortality. Herein, we report a case of uterine wound dehiscence with pelvic abscess following cesarean section, who presented with paralytic ileus and surgical site infection. Read More

Molecules 2022 Jun 7;27(12). Epub 2022 Jun 7.

Pharmaceutical Sciences, Food and Nutrition College, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil.

The aim of this study is to evaluate the phytochemical profile, oral acute toxicity, and the effect of ylang-ylang ( Hook. F. & Thomson) essential oil (YEO) on acute inflammation. Read More

Int J Mol Sci 2022 Jun 9;23(12). Epub 2022 Jun 9.

Department of Obstetrics & Gynecology, Keio University School of Medicine, Tokyo 160-8582, Japan.

Mesenchymal stem cells (MSCs) affect immune cells and exert anti-inflammatory effects. Human amniotic fluid stem cells (hAFSCs), a type of MSCs, have a high therapeutic effect in animal models of inflammation-related diseases. hAFSCs can be easily isolated and cultured from amniotic fluid, which is considered a medical waste. Read More

Proc Natl Acad Sci U S A 2022 Jun 22;119(26):e2123247119. Epub 2022 Jun 22.

Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH 43210.

Mitochondria, a highly metabolically active organelle, have been shown to play an essential role in regulating innate immune function. Mitochondrial Ca uptake via the mitochondrial Ca uniporter (MCU) is an essential process regulating mitochondrial metabolism by targeting key enzymes involved in the tricarboxylic acid cycle (TCA). Accumulative evidence suggests MCU-dependent mitochondrial Ca signaling may bridge the metabolic reprogramming and regulation of immune cell function. Read More

N Z Med J 2022 Mar 11;135(1551):121-124. Epub 2022 Mar 11.

Registrar, Department of General Surgery, North Shore Hospital, Waitematā District Health Board and Postdoctoral Fellow, Department of Department of Molecular Medicine and Pathology, FMHS, University of Auckland.

Pan Afr Med J 2022 18;41:228. Epub 2022 Mar 18.

Department of Surgery, Alex Ekwueme Federal University Teaching Hospital, Abakaliki (AEFUTHA), Ebonyi State, Nigeria.

Introduction: mortality among surgical admissions is a global phenomenon, but the rates, pattern and factors that predict such deaths vary from region to region and even in one region, it varies among institutions. The aim was to document the pattern and factors that influence mortality in the general surgery unit of our institution.

Methods: this was a seven-year retrospective, case-control study. Read More

Pan Afr Med J 2022 17;41:222. Epub 2022 Mar 17.

Gastroenterology Department, Mohamed Tahar Maamouri Hospital, Nabeul, Tunisia.

Jejunal diverticulitis is an uncommon and underdiagnosed condition. Due to the rarity of This disease, diagnosis is often difficult and delayed. Medical treatment is usually sufficient for jejunal diverticulitis without peritonitis. Read More

Dtsch Arztebl Int 2022 Mar;119(12):213

Cureus 2022 May 13;14(5):e24960. Epub 2022 May 13.

Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, IND.

Background Albumin is a negative acute-phase protein as its levels fall after injury, sepsis, and surgical stress. A review of the literature suggests that serum albumin level drops rapidly after surgery in adults and correlates well with the outcomes. However, there is limited data on the use of peri-operative fall in serum albumin levels as an outcome predictor in children undergoing emergency abdominal surgeries. Read More

J Assoc Physicians India 2022 Jun;70(6):11-12

Consultant.

Background: Spontaneous ascitic fluid infection (SAI) is common in cirrhotic patients leading to significant morbidity and mortality. Third-generation cephalosporins are currently recommended as first-line therapy. This is a retrospective observational study that aims to determine bacterial etiology, susceptibility patterns of SAI, and its correlation with model for end-stage liver disease-sodium (MELD-Na) and Child-Turcotte-Pugh (CTP) score. Read More

BMC Nephrol 2022 Jun 11;23(1):207. Epub 2022 Jun 11.

Department of Nephrology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

Background: Technique failure is more likely to occur during the first 12 months after peritoneal dialysis (PD) initiation, which is a great challenge encountered in PD patients. The aim of this study was to investigate the incidence and risk factors associated with technique failure within the first year of PD patients in Southern China.

Methods: Incident PD patients who were followed up for at least one year at The First Affiliated Hospital of Sun Yat-sen University from January 1, 2006 to December 31, 2015 were included. Read More

Med Trop Sante Int 2021 12 26;1(4). Epub 2021 Nov 26.

Département de chirurgie et spécialités, Faculté de médecine et des sciences biomédicales de l'Université de Yaoundé I, Cameroun.

Objective: Acute non-traumatic digestive surgical emergencies are a frequent cause of emergency in Africa. We undertook this study to investigate the morbidity and mortality of these patients in Cameroon, a developing country in Central Africa.

Patients And Methodology: This was an analytical cross-sectional study with prospective data collection, over a period of eight months (November 2019 to July 2020), at the Yaoundé central hospital (Cameroon). Read More

Int J Clin Pract 2022 3;2022:6524717. Epub 2022 Mar 3.

Department of Nephrology, Second Affiliated Hospital of Soochow University, Suzhou, China.

Objective: This study aimed to explore follow-up mode changes for peritoneal dialysis (PD) patients and their effects on PD quality during the COVID-19 pandemic.

Methods: A retrospective single-center study was conducted. All patients who received PD treatment at the Second Affiliated Hospital of Soochow University between January 2018 and March 2020 were enrolled in this study. Read More

World J Surg Oncol 2022 Jun 8;20(1):188. Epub 2022 Jun 8.

Department of Surgical Oncology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005, India.

Introduction: Peritonitis associated with fungal species Curvularia lunata seldom occurs with only five cases reported in the literature, all in middle-age patients with comorbidities undergoing dialysis.

Case Report: A 21-year-old female who was referred to surgical oncology OPD with a diagnosis of ovarian malignancy, based on raised cancer antigen 125 (CA 125) and suspected tubo-ovarian mass (TOM) on magnetic resonance imaging (MRI). A review of the MRI showed a pelvic collection with TOM, suggestive of infective pathology. Read More

Comput Intell Neurosci 2022 27;2022:8658999. Epub 2022 May 27.

Shandong Provincial Maternal and Child Health Care Hospital, Jinan City, Shandong Province, China.

Objective: To explore the prenatal ultrasonographic characteristics and pregnancy outcomes of fetal meconium peritonitis (FMP).

Methods: Nine patients diagnosed with FMP by routine prenatal examination between January 2015 and December 2020 were identified. Both prenatal ultrasonographic characteristics and pregnancy outcomes associated with these patients were retrospectively analyzed. Read More

BMJ Case Rep 2022 Jun 6;15(6). Epub 2022 Jun 6.

Internal Medicine, Kasturba Medical College Manipal, Manipal, Karnataka, India.

Melioidosis is an emerging infectious disease with highest predominance in Southeast Asia, but it has a significantly lower incidence across other parts of the globe. The most common systemic involvement seen in melioidosis is pulmonary, followed by multiple visceral and cutaneous abscesses. Infrequently, melioidosis manifests with atypical presentations such as spontaneous bacterial peritonitis (SBP), acute pyogenic meningitis or septic arthritis. Read More

Biochim Biophys Acta Proteins Proteom 2022 Jul 1;1870(7):140796. Epub 2022 Jun 1.

Department of Nephropathy and Rheumatism, Dongguan Tungwah Hospital, Dongguan, China.

Background: Peritoneal dialysis-associated peritonitis (PDAP) is the most common complication in peritoneal dialysis patients. We propose screening for characteristic expressed proteins in the dialysate of PDAP patients to provide clues for the diagnosis of PDAP and its therapeutic targets.

Methods: Dialysate samples were collected from patients with a first diagnosis of PDAP (n = 15) and from patients who had not experienced peritonitis (Control, n = 15). Read More

Khirurgiia (Mosk) 2022 (6):80-87

N.P. Ogareva National Research Mordovian State University, Saransk, Russia.

The Purpose Of The Work: Based on the determination of the mechanisms of negative manifestations of surgical aggression in open interventions, compared with laparoscopic, to determine ways to optimize the early postoperative period when using them.

Material And Methods: The work is based on clinical and laboratory analysis of 147 patients with acute appendicitis complicated by acute peritonitis. In the first group (=58), patients were operated with traditional laparotomy access. Read More

Pan Afr Med J 2022 8;41:186. Epub 2022 Mar 8.

Faculty of Medicine and Pharmacy of Marrakech Cadi Ayyad University, Microbiology Department, Mohamed VI University Hospital, Marrakech, Morocco.

Comamonas species are rarely associated with human infections. Recent reports found that Comamonas kerstersii was associated with severe diseases such as abdominal infection and bacteremia. However, Comamonas kerstersii may be confused with Comamonas testosteroni using the automatic bacterial identification systems currently available. Read More

JNMA J Nepal Med Assoc 2022 Apr 15;60(248):396-398. Epub 2022 Apr 15.

Department of Medicine, Nepalese Army Institute of Health Sciences, Sanobharyang, Kathmandu, Nepal.

Appendicitis rarely presents with an left lower abdominal pain especially when the intestine is non-rotated or malrotated. Its diagnosis becomes quite troublesome to clinicians and delays prompt intervention. Non-rotation is the most common type of intestinal malrotation. Read More

J Coll Physicians Surg Pak 2022 Apr;32(4):S15-S17

Department of Surgery, University of Health Sciences, Okmeydani Education and Research Hospital, Istanbul, Turkey.

We share our experience of a two-way vacuum-assisted closure (VAC) technique that allows patients to heal when generalised peritonitis develops because of a recurrent duodenal leak. Two patients underwent omentoplasty for duodenal ulcer perforation and one patient underwent antrectomy, gastrojejunostomy, and tube duodenostomy. Two-way VAC was performed by taking an abdominal fluid culture and washing the abdomen with 6-12 litres of warm saline. Read More

Medicine (Baltimore) 2022 May 27;101(21):e29430. Epub 2022 May 27.

Department of Surgery, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Rationale: Few cases have been reported of the coexistence of tuberculosis and adenocarcinoma of the large bowel. We report a rare case of concurrent ascending colon adenocarcinoma and ileocecal tuberculosis, which were nearly indistinguishable from one another.

Patient Concerns: A 59-year-old man visited our clinic with dizziness and anorexia. Read More

World J Emerg Surg 2022 05 26;17(1):25. Epub 2022 May 26.

Research Unit for Surgery, Odense University Hospital, Odense, Denmark.

Background: Secondary peritonitis is a severe condition with a 20-32% reported mortality. The accepted treatment modalities are vacuum-assisted closure (VAC) or primary closure with relaparotomy on-demand (ROD). However, no randomised controlled trial has been completed to compare the two methods potential benefits and disadvantages. Read More

Int Immunopharmacol 2022 Jul 21;108:108856. Epub 2022 May 21.

Division of Pediatric Gastroenterology and Nutrition, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Department of Pediatric Surgery, Xin Hua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China; Shanghai Institute of Pediatric Research, Shanghai, China; Shanghai Key Laboratory of Pediatric Gastroenterology and Nutrition, Shanghai, China. Electronic address:

Methicillin-resistant Staphylococcus aureus (MRSA) has an increasing prevalence of multi-drug resistance. There is an urgent need for developing novel approaches to combat MRSA infection. Mucosal pentraxin 2 (Mptx2) is predicted to be a member of the pentraxin family, but its biological function is still unknown. Read More

PLoS One 2022 24;17(5):e0268823. Epub 2022 May 24.

Division Nephrology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Introduction: We sought to evaluate the predictors and outcomes of mold peritonitis in patients with peritoneal dialysis (PD).

Methods: This cohort study included PD patients from the MycoPDICS database who had fungal peritonitis between July 2015-June 2020. Patient outcomes were analyzed by Kaplan Meier curves and the Log-rank test. Read More

Eur J Anaesthesiol 2022 06;39(6):540-548

From the Division of Anaesthesiology, Intensive Care, Pain and Emergency Medicine, Department of Intensive Care Medicine, Nîmes University Hospital, Nîmes (CR, SL, BL), Equipe d'accueil 2992 Caractéristiques Féminines des Interfaces Vasculaires (IMAGINE), Faculté de médecine, Univ Montpellier, Montpellier (CR, BL), Department of Anesthesiology and Critical Care, Centre Hospitalier Universitaire Lille, Surgical Critical Care, F-59000 Lille (DG), Department of Anaesthesiology and Intensive Care, UNAM University, University of Angers, Angers University Hospital, 49933 Angers (GB), Department of Anesthesia and Critical Care Medicine, Centre Hospitalier Universitaire Amiens Picardie and SSPC Research Unit, Université de Picardie Jules Verne, Amiens (HD), Université Grenoble Alpes, Pôle Anesthésie-Réanimation, Centre Hospitalo-Universitaire Grenoble-Alpes, Grenoble (PB), Service d'anesthésie et des réanimations chirurgicales, Unité de réanimation chirurgicale et neuro-traumatologique, Assistance Publique - Hôpitaux de Paris, Hôpitaux universitaires Henri Mondor, 94000 Créteil (JB), Pôle d'Anesthésie-Réanimation & Médecine Péri-Opératoire, Service d'Anesthésie-Réanimation & Médecine Péri-Opératoire, Hôpital de Hautepierre, Hôpitaux Universitaires de Strasbourg, Strasbourg, France - EA3072, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Faculté de Médecine, Université de Strasbourg, Strasbourg (JP), Université de Paris, INSERM U1152, ANR-10-LABX-17, CHU Bichat-Claude Bernard, APHP, Paris (PM), Département de Médecine d'Urgence, Hôpital de la Timone - AP-HM, Aix Marseille Université, UMR 1263 C2VN, Marseille (PM), CHU Estaing, University of Auvergne, Clermont-Ferrand (SP), Service d'Accueil des Urgences, Hôpital d'Instruction des Armées Percy, Clamart (KA), Hospices Civils de Lyon, centre hospitalier Lyon Sud, service d'Anesthésie-Réanimation, Lyon (PI) and Department of Anaesthesiology and Critical Care, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris Saclay, Le Kremlin Bicêtre, France (AH).

Background: Optimal management of community-acquired intra-abdominal infections (IAI) requires timely surgical source control and adequate anti-infective treatment.

Objective: To describe the initial management of community-acquired IAI admitted to the emergency department and assess the association between the length of time to either diagnosis or therapeutic procedures and patient outcomes.

Design: A prospective, multicentre, observational study. Read More

Medicine (Baltimore) 2022 May 20;101(20):e29217. Epub 2022 May 20.

Centre for Liver Disease Research, Faculty of Medicine, the University of Queensland, Brisbane, QLD, Australia.

Abstract: Spontaneous bacterial peritonitis (SBP), a common infection in patients with cirrhosis and ascites, is associated with high morbidity and mortality. The aim of this study was to investigate changes in the epidemiology of ascites fluid infections over time in an Australian population, including patient demographics, trends in mortality, length of hospital stay and the nature and antibiotic resistance profile of causative organisms.An observational descriptive population-based epidemiological study of patients with cirrhosis admitted to public hospitals in Queensland during 2008-2017 was performed, linking demographic/clinical and microbiology data. Read More