Int J Mol Sci 2021 Mar 30;22(7). Epub 2021 Mar 30.
Department of Gastroenterology and Neurology, Kagawa University School of Medicine, Kagawa 761-0793, Japan.
The liver is well recognized as a non-immunological visceral organ that is involved in various metabolic activities, nutrient storage, and detoxification. Recently, many studies have demonstrated that resident immune cells in the liver drive various immunological reactions by means of several molecular modulators. Understanding the mechanistic details of interactions between hepatic host immune cells, including Kupffer cells and lymphocytes, and various hepatic pathogens, especially viruses, bacteria, and parasites, is necessary. Read More