4,653 results match your criteria Peritoneal Dialysis International[Journal]


Safety of Intravenous Iron - Cosmofer and Monofer Therapy in Peritoneal Dialysis and Non-Dialysis-Dependent Chronic Kidney Disease Patients.

Perit Dial Int 2019 Mar-Apr;39(2):192-195

Hull & East Yorkshire Hospitals NHS Trust, Hull Royal Infirmary, Hull, UK

Safety of parenteral iron therapy is critical and has been demonstrated in several studies, but concerns persist on safety. We performed a retrospective single-center study investigating the safety and efficacy of parenteral iron administration using 2 iron preparations-Monofer and Cosmofer (Pharmacosmos A/S, Holbaek, Denmark)-in patients with chronic kidney disease (CKD), on peritoneal dialysis (PD) and non-dialysis. A database of CKD patients receiving intravenous (IV) iron was analyzed. Read More

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http://dx.doi.org/10.3747/pdi.2018.00125DOI Listing

Performance of Gram Stains and 3 Culture Methods in the Analysis of Peritoneal Dialysis Fluid.

Perit Dial Int 2019 Mar-Apr;39(2):190-192

Division of Infection, Barts Health NHS Trust, Royal London Hospital, Whitechapel Road, London, UK.

Microbiological diagnosis of peritoneal dialysis (PD)-related peritonitis includes PD fluid cell count, Gram stain, and culture, as recommended by the International Society for Peritoneal Dialysis. In this retrospective study, we examined the utility of Gram stains and compared 3 culture methods.We examined a laboratory cohort (samples sent to the laboratory for any reason; = 251) and a clinical cohort (samples sent from patients felt clinically to have peritonitis; = 264). Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00087
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http://dx.doi.org/10.3747/pdi.2018.00087DOI Listing
March 2019
3 Reads

Extended Experience in the Use of Antibiotic Lock for Eradication of Biofilm Bacteria on Tenckhoff Catheter.

Perit Dial Int 2019 Mar-Apr;39(2):187-190

Department of Medicine, Alice Ho Miu Ling Nethersole Hospital, Hong Kong.

Whilst antibiotic lock is effective to eradicate biofilm bacteria on hemodialysis catheters, this adjunctive method has scarcely been tested in peritoneal dialysis (PD) patients. After our previous successful experience of its use to salvage two Tenckhoff catheters, we encountered another patient with problematic biofilm-associated PD peritonitis who strongly refused catheter removal. As a result, antibiotic lock was given once daily, initially, with continuation of the usual PD schedule. Read More

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http://dx.doi.org/10.3747/pdi.2018.00098DOI Listing
March 2019
2.199 Impact Factor

Vancomycin Removal During High-Volume Peritoneal Dialysis in Acute Kidney Injury Patients.

Perit Dial Int 2019 Mar-Apr;39(2):183-187

UC San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, University of San Diego, California, USA.

Studies on vancomycin pharmacokinetics in acute kidney injury (AKI) patients on high-volume peritoneal dialysis (HVPD) are lacking. We studied the pharmacokinetics of intravenous (IV) vancomycin in AKI patients treated by HVPD who received a prescribed single IV dose of vancomycin (15 - 20 mg/kg total body weight) to determine the extent of vancomycin removal and to establish vancomycin dosing guidelines for the empirical treatment of AKI patients receiving HVPD. The application of 18 mg/kg vancomycin every 48 - 72 hours in AKI patients undergoing HVPD was required to maintain therapeutic concentrations. Read More

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http://dx.doi.org/10.3747/pdi.2018.00092DOI Listing

Predictors of Quality of Life among Peritoneal Dialysis Patients with End-Stage Renal Disease in Kuwait.

Perit Dial Int 2019 Mar-Apr;39(2):180-182

Department of Community Medicine and Behavioral Sciences, Faculty of Medicine, Kuwait University, Kuwait

Quality of life (QOL) is an important indicator of quality of healthcare. Measuring QOL and its correlates for peritoneal dialysis (PD) patients is important for public health policy, intervention, and clinical decision-making. Data from 62 patients treated at 6 dialysis centers were collected using short form (SF)-36. Read More

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http://dx.doi.org/10.3747/pdi.2018.00140DOI Listing
March 2019
2.199 Impact Factor

Evaluating Burden and Quality of Life among Caregivers of Patients Receiving Peritoneal Dialysis.

Perit Dial Int 2019 Mar-Apr;39(2):176-180

Department of Psychology, National University of Singapore, Singapore

Peritoneal dialysis (PD) is advocated as treatment of choice for most end-stage renal disease (ESRD) patients, including elderly and frail patients. It typically requires caregiver involvement to support care at home. The purpose of this study was to examine changes in burden and quality of life (QOL) in caregivers of prevalent PD patients over 12 months. Read More

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http://dx.doi.org/10.3747/pdi.2018.00049DOI Listing

Peritonitis in Peritoneal Dialysis in Northern China: A Case Report.

Perit Dial Int 2019 Mar-Apr;39(2):175-176

Microbiology Laboratory, The Affiliated Yantai Yuhuangding Hospital of Qingdao University Institution, Yantai, China

Fungal peritonitis is a catastrophic complication of peritoneal dialysis (PD) and often requires termination of PD. It is usually caused by species. Here we report a rare case of peritonitis. Read More

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http://dx.doi.org/10.3747/pdi.2018.00184DOI Listing

THE ASSOCIATION OF COGNITIVE IMPAIRMENT WITH PERITONEAL DIALYSIS-RELATED PERITONITIS.

Perit Dial Int 2019 Mar 9. Epub 2019 Mar 9.

Department of Medicine, Peking University First Hospital, Beijing, China

Background: Research on the association between cognitive impairment (CI) and peritoneal dialysis (PD)-related peritonitis is limited. Therefore, we investigated whether CI contributed to the risk of PD-related peritonitis.

Methods: This prospective cohort study enrolled 458 patients from 5 PD centers between 1 March 2013, and 30 November 2013, and continued until 31 May 2016. Read More

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http://dx.doi.org/10.3747/pdi.2018.00180DOI Listing

END-STAGE RENAL DISEASE PATIENTS WITH LOW SERUM ALBUMIN: IS PERITONEAL DIALYSIS AN OPTION?

Perit Dial Int 2019 Mar 9. Epub 2019 Mar 9.

Medicine, University of Wisconsin School fo Medicine and Public Health, Madison, United States.

Introduction: Low serum albumin is associated with high mortality in patients with end-stage renal disease (ESRD) on chronic dialysis. Clinicians are reluctant to offer peritoneal dialysis (PD) as an option for dialysis for patients with low serum albumin due to concerns of loss of albumin with PD, but evidence supporting differences in outcomes is limited. We evaluated mortality based on dialysis modality in patients with very low serum albumin (<2. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00204
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http://dx.doi.org/10.3747/pdi.2018.00204DOI Listing
March 2019
12 Reads

SIMULTANEOUS REMOVAL AND REINSERTION OF THE PD CATHETER IN RELAPSING PERITONITIS.

Perit Dial Int 2019 Mar 9. Epub 2019 Mar 9.

Nephrology, CHU de Caen, Caen, France.

Background: Relapsing peritonitis in peritoneal dialysis (PD) is associated with lower cure rates and more hemodialysis (HD) transfers, as catheter removal is recommended in these situations. The aim of our study was to evaluate the continuation of PD without perioperative transfer to HD in patients who underwent a simultaneous catheter removal and replacement for relapsing peritonitis.

Methods: This was a retrospective monocentric study. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00230
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http://dx.doi.org/10.3747/pdi.2018.00230DOI Listing
March 2019
5 Reads

ICODEXTRIN IS ASSOCIATED WITH A LOWER MORTALITY RATE IN PERITONEAL DIALYSIS PATIENTS.

Perit Dial Int 2019 Mar 9. Epub 2019 Mar 9.

Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Background: Icodextrin (ICO) improves fluid removal in peritoneal dialysis (PD) patients. However, whether physiological benefits of ICO translate into patient survival remains unclear. We examine the association of ICO and clinical outcomes. Read More

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http://dx.doi.org/10.3747/pdi.2018.00217DOI Listing
March 2019
1 Read

CONSTIPATION IN PERITONEAL DIALYSIS PATIENTS.

Perit Dial Int 2019 Mar 9. Epub 2019 Mar 9.

Pole Metabolique and Dialysis Unit, Centre Hospitalier Jacques Lacarin, VICHY, France.

Constipation in peritoneal dialysis (PD) is an infrequent but potentially serious condition affecting the mechanical properties of dialysis techniques and predisposing to bacterial intestinal translocation and eventual enteric peritonitis. Despite the importance of the problem, published literature is scarce, consisting mostly of uncontrolled single-center trials. This inconsistency may be attributed to the large number of clinical, radiological, and endoscopic tools that have been used in the studies with a lack of generally accepted core primary outcomes. Read More

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http://dx.doi.org/10.3747/pdi.2018.00169DOI Listing

ARE ISPD GUIDELINES ON PERITONITIS DIAGNOSIS TOO NARROW? A 15-YEAR RETROSPECTIVE SINGLE-CENTER COHORT STUDY ON PD-ASSOCIATED PERITONITIS ACCOUNTING FOR UNTRAINED PATIENTS.

Perit Dial Int 2019 Mar 6. Epub 2019 Mar 6.

Nephrology & Hypertension, Medizinische Hochschule Hannover, Hannover, Germany.

Background: Peritoneal dialysis (PD)-associated peritonitis remains by far the most important complication requiring patients to transfer to hemodialysis and has a major impact on patient morbidity and mortality. Current International Society for Peritoneal Dialysis (ISPD) guidelines on peritonitis recommend analysis of peritonitis episodes only in trained patients. In a large tertiary care center, we analyzed peritonitis episodes accounting for different groups of untrained patients and compared these with episodes in the trained patient population. Read More

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http://dx.doi.org/10.3747/pdi.2018.00179DOI Listing

BURDEN AND CORRELATES OF HOSPITAL READMISSIONS AMONG U.S. PERITONEAL DIALYSIS PATIENTS.

Perit Dial Int 2019 Mar 6. Epub 2019 Mar 6.

Department of Medicine, Emory University, Atlanta, United States

Background: Hospital readmissions are common among in-center hemodialysis patients, but little is known about readmissions among peritoneal dialysis (PD) patients. Using national administrative data, we aimed to examine the burden and correlates of hospital readmissions among U.S. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00175
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http://dx.doi.org/10.3747/pdi.2018.00175DOI Listing
March 2019
3 Reads

EFFECTS OF EXCESSIVE BODY FAT ACCUMULATION ON LONG-TERM OUTCOMES DURING PERITONEAL DIALYSIS.

Perit Dial Int 2019 Mar 6. Epub 2019 Mar 6.

Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea, Republic of.

Background: Significant body fat accumulation is an inevitable but potentially serious problem in peritoneal dialysis (PD) patients. Whether excessive fat gain predicts long-term outcomes in these patients remains unknown.

Methods: In this prospective cohort study (n = 297), the associations of excessive fat accumulation with patient survival and PD failure rate were examined. Read More

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http://dx.doi.org/10.3747/pdi.2018.00164DOI Listing

COMPUTER SIMULATIONS OF CONTINUOUS FLOW PERITONEAL DIALYSIS USING THE 3-PORE MODEL-A FIRST EXPERIENCE.

Perit Dial Int 2019 Mar 6. Epub 2019 Mar 6.

Department of Clinical Sciences Lund, Renal Physiology and Peritoneal Dialysis Group, Lund University, Lund, Sweden.

Background: Continuous flow peritoneal dialysis (CFPD) is performed using a continuous flux of dialysis fluid via double or dual-lumen PD catheters, allowing a higher dialysate flow rate (DFR) than conventional treatments. While small clinical studies have revealed greatly improved clearances using CFPD, the inability to predict ultrafiltration (UF) may confer a risk of potentially harmful overfill. Here we performed physiological studies of CFPD in silico using the extended 3-pore model. Read More

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http://dx.doi.org/10.3747/pdi.2018.00225DOI Listing

PERITONEAL DIALYSIS CUFF-SHAVING-A SALVAGE THERAPY FOR REFRACTORY EXIT-SITE INFECTIONS.

Perit Dial Int 2019 Mar 6. Epub 2019 Mar 6.

Nefrologia, Centro Hospitalar de São João, Porto, Portugal.

Introduction: Cuff-shaving has been described as a salvage technique for refractory exit-site infections, with conflicting data regarding infection and catheter outcomes. We describe our experience with cuff-shaving as a rescue therapy for exit-site infections unresponsive to systemic therapy.

Methods: We retrospectively reviewed patients who underwent cuff-shaving between January 2012 and June 2017. Read More

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http://dx.doi.org/10.3747/pdi.2018.00193DOI Listing
March 2019
1 Read

Clinical Value of Screening Peritoneal Dialysis Patients for Bacterial Colonization or Contamination.

Perit Dial Int 2019 Mar-Apr;39(2):126-133. Epub 2019 Feb 9.

Department of Renal Medicine and Transplantation, Barts Health NHS Trust, London, UK

Introduction: The adoption of the International Society for Peritoneal Dialysis guideline of using mupirocin ointment has been limited by fear of developing mupirocin-resistant organisms. We performed a surveillance program of a large peritoneal dialysis (PD) unit.

Methods: We performed 1,175 surveillance swabs from anterior nares, PD catheter exit site, groin, and axilla, from 240 patients. Read More

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http://dx.doi.org/10.3747/pdi.2018.00082DOI Listing
February 2019
3 Reads

The Association of Functional Status with Mortality and Dialysis Modality Change: Results from the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS).

Perit Dial Int 2019 Mar-Apr;39(2):103-111. Epub 2019 Feb 9.

St. Michael's Hospital, Toronto, ON, Canada

Background: Little is known about the prevalence of functional impairment in peritoneal dialysis (PD) patients, its variation by country, and its association with mortality or transfer to hemodialysis.

Methods: A prospective cohort study was conducted in PD patients from 7 countries in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) (2014 - 2017). Functional status (FS) was assessed by combining self-reports of 8 instrumental and 5 basic activities of daily living, using the Lawton-Brody and the Katz questionnaires. Read More

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http://dx.doi.org/10.3747/pdi.2018.00094DOI Listing
February 2019
2 Reads

Peritoneal Dialysis-Related Peritonitis from Carbapenemase-Producing with OXA-48 Type Gene.

Perit Dial Int 2019 Jan-Feb;39(1):97-98

National University Hospital - Medicine, (Division of Nephrology), Singapore

We report a rare case of carbapenemase-producing enterobacte-riaceae peritonitis in a patient undergoing automated peritoneal dialysis (APD). The PD catheter had to be removed as the patient remained unwell despite antibiotics. Antimicrobial resistance in PD peritonitis is a concern in this era of multi-drug resistant bacteria. Read More

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http://dx.doi.org/10.3747/pdi.2018.00234DOI Listing
January 2019

Laparoscopic Mesh Repair of Bilateral Obturator Hernias Post-Peritoneal Dialysis.

Perit Dial Int 2019 Jan-Feb;39(1):95-97

St. Paul's Hospital, Department of General Surgery, Vancouver, BC, Canada.

Abdominal wall hernias are prevalent in patients undergoing peritoneal dialysis (PD). Obturator hernias, first described by Arnaud de Ronsil in 1724, are an uncommon type of hernia where intra-abdominal contents protrude through the obturator foramen. The following case highlights a rare presentation of bilateral obturator hernias with right femoral and inguinal hernia in an 82-year-old woman post-PD. Read More

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http://dx.doi.org/10.3747/pdi.2018.00203DOI Listing
January 2019
2 Reads

: An Outbreak in the Peritoneal Dialysis Unit.

Perit Dial Int 2019 Jan-Feb;39(1):92-95

Department of Renal Medicine, Middlemore Hospital, Auckland, New Zealand.

is a ubiquitous, opportunistic, environmental gram-negative bacillus which most commonly affects cystic fibrosis and immunocompromised patients. Rarely, it can cause peritoneal dialysis (PD) exit-site infection (ESI). Information relating to predisposing factors, clinical course, and treatment options for ESIs is limited. Read More

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http://dx.doi.org/10.3747/pdi.2018.00095DOI Listing
January 2019
1 Read

Increase of Eosinophil in Dialysate During Induction of Peritoneal Dialysis.

Perit Dial Int 2019 Jan-Feb;39(1):90-92

Nephrology, Nagoya University Postgraduate School of Medicine, Nagoya, Japan.

As a rare complication in patients on peritoneal dialysis (PD), increase of eosinophil (peritoneal dialysate fluid [PDF] eosinophilia), including eosinophilic peritonitis, was observed in PDF. The majority of eosinophilic peritonitis cases are detected during the early phase of PD induction. However, the frequency of and mechanisms underlying PDF eosinophilia remain unclear. Read More

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http://dx.doi.org/10.3747/pdi.2017.00205DOI Listing
January 2019
2 Reads

The Importance of Context to Interpretation of Dialysis Access Patterns: Insights from the UK Renal Registry Data Set.

Authors:
Barny Hole

Perit Dial Int 2019 Jan-Feb;39(1):19-24

University of Bristol and UK Renal Registry, Bristol, UK

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http://dx.doi.org/10.3747/pdi.2018.00124DOI Listing
January 2019

Transition Between Different Renal Replacement Modalities: Gaps in Knowledge and Care-The Integrated Research Initiative.

Perit Dial Int 2019 Jan-Feb;39(1):4-12

Ghent University Hospital, Ghent, Belgium

Patients with end-stage kidney disease (ESKD) have different options to replace the function of their failing kidneys. The "integrated care" model considers treatment pathways rather than individual renal replacement therapy (RRT) techniques. In such a paradigm, the optimal strategy to plan and enact transitions between the different modalities is very relevant, but so far, only limited data on transitions have been published. Read More

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http://dx.doi.org/10.3747/pdi.2017.00242DOI Listing
November 2017
2 Reads
2.199 Impact Factor

Transition-The Process of Changing from One State to Another.

Authors:
Martin Wilkie

Perit Dial Int 2019 Jan-Feb;39(1)

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http://dx.doi.org/10.3747/pdi.2018.00210DOI Listing
January 2019

Longitudinal Trends in Quality of Life and Physical Function in Frail Older Dialysis Patients: A Comparison of Assisted Peritoneal Dialysis and In-Center Hemodialysis.

Perit Dial Int 2019 Mar-Apr;39(2):112-118. Epub 2019 Jan 18.

UCL Centre for Nephrology, Royal Free Hospital, London, UK.

Background: In-center hemodialysis (HD) has been the standard treatment for older dialysis patients, but reports suggest an associated decline in physical and cognitive function. Cross-sectional data suggest that assisted peritoneal dialysis (aPD), an alternative treatment, is associated with quality of life (QoL) outcomes that are comparable to in-center HD. We compared longitudinal changes in QoL between modalities. Read More

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http://dx.doi.org/10.3747/pdi.2018.00086DOI Listing
January 2019
3 Reads

FLUID TONICITY AFFECTS PERITONEAL CHARACTERISTICS DERIVED BY 3-PORE MODEL.

Perit Dial Int 2019 Jan 18. Epub 2019 Jan 18.

Department of Modeling and Supporting of Internal Organs Functions , Nalecz Institute of Biocybernetics and Biomedical Engineering, Warsaw, Poland.

Background: It is typically assumed that within short timeframes, patient-specific peritoneal membrane characteristics are constant and do not depend on the initial fluid tonicity and dwell duration. The aim of this study was to check whether this assumption holds when membrane properties are estimated using the 3-pore model (3PM).

Methods: Thirty-two stable peritoneal dialysis (PD) patients underwent 3 8-hour peritoneal equilibration tests (PETs) with different glucose-based solutions (1. Read More

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http://dx.doi.org/10.3747/pdi.2017.00267DOI Listing
January 2019
2 Reads

B-TYPE NATRIURETIC PEPTIDE LEVELS AND CARDIAC DYSFUNCTION IN CHILDREN ON PERITONEAL DIALYSIS.

Perit Dial Int 2019 Jan 18. Epub 2019 Jan 18.

Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea (the Republic of)

Background: Abnormalities in left ventricular (LV) structure and function are prevalent in patients on peritoneal dialysis (PD). The risk of cardiovascular mortality is also 10 - 20 times higher in PD patients than in age- and gender-matched healthy control subjects.

Methods: Echocardiography was performed annually or every 6 months for children on PD; the frequency was increased if the patient had hypertension or any heart problem. Read More

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http://dx.doi.org/10.3747/pdi.2018.00150DOI Listing
January 2019
2 Reads

An Intervention Design: Supporting Skills Development for Peritoneal Dialysis Trainers.

Perit Dial Int 2019 Mar-Apr;39(2):134-141. Epub 2019 Jan 18.

Medical School, University of Western Australia, Perth, Australia.

Background: Peritoneal dialysis (PD) is a home-based therapy where nurses train patients in its use. There has been no published randomized controlled trial (RCT) evaluating any specific protocol for nurses delivering PD training. A standardized education package based upon the best available evidence and utilizing modern educational practices may lead to improved patient outcomes. Read More

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http://dx.doi.org/10.3747/pdi.2018.00159DOI Listing
January 2019
8 Reads

Relationships Between Peritoneal Protein Clearance and Parameters of Fluid Status Agree with Clinical Observations in Other Diseases that Venous Congestion Increases Microvascular Protein Escape.

Perit Dial Int 2019 Mar-Apr;39(2):155-162. Epub 2019 Jan 18.

UCL Center for Nephrology, Royal Free Hospital, University College London, United Kingdom

Background: Peritoneal effluent from peritoneal dialysis (PD) patients contains proteins, mainly transported from the circulation through large pores in the venular part of the peritoneal microvessels. Hydrostatic convection is the major driver for peritoneal protein transport, although in PD there is additional diffusion. Consequently, venous pressure may have a role in peritoneal protein transport. Read More

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http://dx.doi.org/10.3747/pdi.2018.00016DOI Listing
January 2019
2 Reads

Insights on Peritoneal Dialysis in China.

Perit Dial Int 2018 12;38(Suppl 2):S16-S18

The series of papers that are included in this China Supplement to chart peritoneal dialysis (PD) research over the last several years in that country, provide detailed analysis of a large de-identified dataset from the Baxter Patient Support Program, and include 2 papers that describe clinical experiences relevant to the local context. These studies present a fascinating insight into the practice of PD in China, adding considerably to the sum of worldwide PD experience. China presents important opportunities for clinical research to answer key questions relevant to our therapy. Read More

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http://dx.doi.org/10.3747/pdi.2018.00224DOI Listing
December 2018
2 Reads

Health Literacy-How Do We Improve the Conversation at the Heart of Healthcare when We Know so Many People are Struggling with It?

Perit Dial Int 2019 Jan-Feb;39(1):13-18. Epub 2018 Nov 25.

NHS Education for Scotland, Edinburgh, United Kingdom.

The Scottish Government published "Making it Easy - A Health Literacy Action Plan for Scotland" in 2014, and in 2017 the next steps were set out in "Making it Easier - A Health Literacy Action Plan for Scotland 2017-2025." This article discusses what health literacy is, outlining the key points from these national action plans. The importance of understanding and addressing health literacy in relation to renal services, and dialysis in particular, is highlighted by use of an example of a Scottish renal unit's practice to outline the principles being used in a service. Read More

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http://dx.doi.org/10.3747/pdi.2018.00117DOI Listing
November 2018
12 Reads

Exercise Capacity and Association with Quality of Life in Peritoneal Dialysis Patients.

Perit Dial Int 2019 Jan-Feb;39(1):66-73. Epub 2018 Nov 25.

Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan.

Background: Muscle wasting, common and progressive in uremic patients, is associated with a high probability for morbidity, lower health-related quality of life (HRQOL), and mortality. However, exercise tolerance in peritoneal dialysis (PD) patients has not been fully elucidated. The aim of this study was to evaluate exercise capacity, its determinants, and its association with HRQOL in PD patients. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00075
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http://dx.doi.org/10.3747/pdi.2018.00075DOI Listing
November 2018
32 Reads

Epithelial-to-Mesenchymal Transition and Migration of Human Peritoneal Mesothelial Cells Undergoing Senescence.

Perit Dial Int 2019 Jan-Feb;39(1):35-41. Epub 2018 Nov 25.

Department of Nephrology and Medical Intensive Care, Charité-Universitätsmedizin Berlin, Campus Virchow-Klinikum, Berlin, Germany

Background: Epithelial-to-mesenchymal transition (EMT) of human peritoneal mesothelial cells (HPMCs) contributes to fibrotic thickening of the peritoneum that develops in patients on peritoneal dialysis (PD). The process is thought to be largely mediated by transforming growth factor-beta (TGF-β). As TGF-β has also been implicated in senescence of HPMCs, we have performed an exploratory study to examine if senescent HPMCs can undergo EMT. Read More

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http://dx.doi.org/10.3747/pdi.2017.00244DOI Listing
November 2018
2 Reads

Association of B-Type Natriuretic Peptide Level With Residual Kidney Function in Incident Peritoneal Dialysis Patients.

Perit Dial Int 2019 Mar-Apr;39(2):147-154. Epub 2018 Nov 25.

Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Background: Residual kidney function (RKF) is an important factor influencing both technique and patient survival in peritoneal dialysis (PD) patients. B-type natriuretic peptide (BNP) is considered a marker of cardio-renal syndrome. The relationship between BNP and RKF in PD patients remains unclear. Read More

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http://dx.doi.org/10.3747/pdi.2017.00241DOI Listing
November 2018
1 Read

Outcomes of the Weighted Peritoneal Dialysis Catheter in Patients at Risk of Percutaneous Catheter Failure.

Perit Dial Int 2019 Mar-Apr;39(2):142-146. Epub 2018 Nov 25.

Vascular Department, Heart of England NHS Trust, Birmingham, UK.

Background: The weighted catheter has shown promising results in retrospective and randomized studies. We examined its usefulness in patients with previous failed non-weighted peritoneal dialysis (PD) catheters or previous abdominal surgery.

Methods: The insertion, start, end, and removal dates were recorded for all-type catheter insertions from 2011 to 2016. Read More

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http://dx.doi.org/10.3747/pdi.2017.00233DOI Listing
November 2018
3 Reads

Early Detection of Imminent Encapsulating Peritoneal Sclerosis: Free Water Transport, Selected Effluent Proteins, or Both?

Perit Dial Int 2019 Jan-Feb;39(1):83-89. Epub 2018 Nov 25.

Division of Nephrology, Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Background: No diagnostic tool or methodology is currently available for early detection of imminent encapsulating peritoneal sclerosis (EPS). The objective of this study was to investigate the predictive value of free water transport (FWT) and construct a panel of peritoneal effluent proteins for EPS alone or in combination with FWT. These parameters could be incorporated in the follow-up of peritoneal dialysis (PD) patients. Read More

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http://dx.doi.org/10.3747/pdi.2017.00194DOI Listing
November 2018
2 Reads

Sustained Increase in Peritoneal Dialysis Prevalence through a Structured PD Initiation Service.

Authors:

Perit Dial Int 2018 Nov-Dec;38(6):470

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http://dx.doi.org/10.3747/pdi.2018.01001DOI Listing
November 2018
1 Read

More on Suprapubic Catheters and Peritoneal Dialysis.

Perit Dial Int 2018 Nov-Dec;38(6):467-468

Department of Nephrology, 4 Department of Internal Medicine, Klinikum Wels-Grieskirchen, Wels, Austria

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http://dx.doi.org/10.3747/pdi.2018.00127DOI Listing
November 2018
2 Reads

Pharmacokinetics of 300 mg/d Intraperitoneal Daptomycin: New Insight from the DaptoDP Study.

Perit Dial Int 2018 Nov-Dec;38(6):463-466

Nephrology Department, CHU de Caen, Caen, FRANCE.

The DaptoDP (NCT 2012-005699-33) study aimed to evaluate the pharmacokinetic parameters of daptomycin (DAP) in peritoneal dialysis-related peritonitis (PDRP) patients following intraperitoneal (IP) administration. The authors have already reported the findings on the 200-mg dosing and present here the follow-up results of the 300-mg dosing. The primary endpoint was a dialysate concentration of DAP above the effective concentration during 6 hours of dwell time i. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2017.00256
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http://dx.doi.org/10.3747/pdi.2017.00256DOI Listing
March 2019
19 Reads

Exit-Site Infection: A Comparison of Classification Systems.

Perit Dial Int 2018 Nov-Dec;38(6):462-463

Sri Venkateswara Institute of Medical Sciences, Nephrology, Andhra Pradesh, India.

In general, in peritoneal dialysis (PD) practice in hospitals, Twardowski and Prowant's exit-site classification system is used, while the International Society for Peritoneal Dialysis (ISPD) exit-site scoring system is practical to use in community visits with less experienced healthcare personnel. Nevertheless, when exit-site scoring is 3 points under the ISPD exit-site score system and it falls in the category of equivocal under the Twardowski and Prowant's exit-site classification, the physician should be vigilant about the possibility of developing peritonitis, and hence, patients need to be kept under periodic monitoring. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00013
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http://dx.doi.org/10.3747/pdi.2018.00013DOI Listing
March 2019
22 Reads
2.199 Impact Factor

Gastric Electrical Stimulation Improves Symptoms of Diabetic Gastroparesis in Patients on Peritoneal Dialysis-2 Case Reports.

Perit Dial Int 2018 Nov-Dec;38(6):458-462

Department of Gastroenterology, Clinical Hospital Centre Rijeka, Faculty of Medicine, University of Rijeka, Croatia.

Diabetic gastroparesis (DGP), a delay in gastric emptying without obstruction to outflow as a complication of diabetes, typically develops after at least 10 years of diabetes. Cardinal symptoms include nausea, vomiting, early satiety, bloating, and upper abdominal pain. The aim of DGP treatment is to alleviate the severity and frequency of symptoms, improve the level of gastric emptying, ameliorate the patient's nutritional status and to optimize glycemic control. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00063
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http://dx.doi.org/10.3747/pdi.2018.00063DOI Listing
March 2019
20 Reads

Changing Dialysis Modality during Pregnancy: A Case Report.

Perit Dial Int 2018 Nov-Dec;38(6):456-458

Section of Nephrology, Department of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, MB, Canada

Pregnancy in patients with end-stage renal disease is rare, with a paucity of management guidelines in the literature. Various hemodialysis (HD) and peritoneal dialysis (PD) protocols have been used to successfully manage pregnancy in this population; however, there is a growing body of evidence that the best maternal and fetal outcomes are associated with intensified, high-dose HD. The optimal timing of transition from PD to HD is not known for prevalent PD patients who become pregnant. Read More

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http://dx.doi.org/10.3747/pdi.2018.00054DOI Listing
March 2019
10 Reads

Hemoperitoneum in a Peritoneal Dialysis Patient: Ruptured Ectopic Pregnancy.

Perit Dial Int 2018 Nov-Dec;38(6):455-456

Surgery, University of Chicago Medical Center, Chicago, IL, USA.

Hemoperitoneum is a well-recognized complication in female peritoneal dialysis (PD) patients of childbearing age. Bloody effluent is commonly of minor nature, presenting during menstruation or midcycle, resolving after a few rapid exchanges without a need for further intervention. One must remain vigilant, however, and consider a broader differential diagnosis when hemoperitoneum is persistent or severe, as it indicates a serious and potentially life-threatening etiology. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00066
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http://dx.doi.org/10.3747/pdi.2018.00066DOI Listing
March 2019
16 Reads

Challenges Facing Children on Chronic Peritoneal Dialysis in South Africa.

Perit Dial Int 2018 Nov-Dec;38(6):402-404

Division of Paediatric Haematology and Oncology, Department of Paediatrics and Child Health, Charlotte Maxeke Johannesburg Academic Hospital and the University of the Witwatersrand, Johannesburg, South Africa.

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http://dx.doi.org/10.3747/pdi.2017.00275DOI Listing
March 2019
4 Reads

Peritoneal Dialysis for Patients with End-Stage Renal Disease and Liver Cirrhosis.

Perit Dial Int 2018 Nov-Dec;38(6):397-401

Division of Nephrology, University of Virginia Health System, Charlottesville, VA, USA.

End-stage renal disease patients with cirrhosis represent a therapeutic dilemma, with several difficulties associated with hemodialysis as a renal replacement therapy modality. Peritoneal dialysis is a feasible option for these patients, despite the confounders of associated infection risk, malnutrition, ascites management, and mechanical complications. This review covers the existing data on the outcomes and complications associated with the use of peritoneal dialysis in the cirrhotic patient. Read More

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http://www.pdiconnect.com/lookup/doi/10.3747/pdi.2018.00008
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http://dx.doi.org/10.3747/pdi.2018.00008DOI Listing
March 2019
11 Reads

Peritonitis in a Patient on Peritoneal Dialysis: Case Report and Literature Review.

Perit Dial Int 2018 12 12;38(Suppl 2):S64-S68. Epub 2018 Oct 12.

Department of Nephrology, Peking University People's Hospital, Beijing, China.

Peritonitis is the most common complication in patients undergoing peritoneal dialysis (PD). Peritoneal dialysis-related peritonitis caused by species has been reported in only 7 patients before. Here, we report a further case of peritonitis. Read More

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http://dx.doi.org/10.3747/pdi.2018.00115DOI Listing
December 2018
1 Read