1,123 results match your criteria Perirectal Abscess


USA300 Staphylococcus aureus persists on multiple body sites following an infection.

BMC Microbiol 2018 Dec 5;18(1):206. Epub 2018 Dec 5.

Department of Medicine, Division of Infectious Diseases, University of Pennsylvania, Philadelphia, PA, USA.

Background: USA300 methicillin-resistant Staphylococcus aureus (MRSA) is a community- and hospital-acquired pathogen that frequently causes infections but also can survive on the human body asymptomatically as a part of the normal microbiota. We devised a comparative genomic strategy to track colonizing USA300 at different body sites after an initial infection. We sampled ST8 S. Read More

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December 2018

Magnetic resonance sentinel lymph node imaging and magnetometer-guided intraoperative detection in prostate cancer using superparamagnetic iron oxide nanoparticles.

Int J Nanomedicine 2018 23;13:6689-6698. Epub 2018 Oct 23.

University Hospital for Urology, Klinikum Oldenburg, School of Medicine and Health Sciences, Carl von Ossietzky University Oldenburg, Oldenburg, Germany,

Purpose: Sentinel lymph node (LN) dissection (sLND) using a magnetometer and superpara-magnetic iron oxide nanoparticles (SPION) as a tracer was successfully applied in prostate cancer (PCa). The feasibility of sentinel LN (SLN) visualization on MRI after intraprostatic SPION injection has been reported. In the present study, results of preoperative MRI identification of SLNs and the outcome of subsequent intraoperative magnetometer-guided sLND following intraprostatic SPION injection were studied in intermediate- and high-risk PCa. Read More

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October 2018
4 Reads

Overstaged Rectal Cancer by MRI due to Fibrosis Induced by Tattoo Marker.

Case Rep Gastroenterol 2018 Sep-Dec;12(3):602-607. Epub 2018 Oct 2.

Institute of Pathology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.

Endoscopic colorectal tattooing with carbon-based dyes is commonly employed in order to assist with later localization of the lesion. Although carbon is thought to be nontoxic, there usually is some inflammatory reaction with fibrosis and granuloma formation after tissue injection. The aim of this report is to alert to a possible underestimated, late consequence of colorectal carbon-based marker tattooing, namely pronounced fibrosis at the site of the injection that could lead to a blurring and misinterpretation of changes evaluated by radiological techniques. Read More

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October 2018
6 Reads

Distinct Imaging Characteristics of Different Metastases From Primary Prostate Adenocarcinoma and Rectal Carcinoid Tumor on 18F-Fluciclovine and 68Ga-DOTATATE PET/CT.

Clin Nucl Med 2019 Jan;44(1):83-84

Department of Nuclear Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China.

A 71-year-old man with history of prostate cancer is evaluated for rising prostate-specific antigen. The patient also has a history of rectal well-differentiated neuroendocrine tumor. On F-fluciclovine PET/CT, 2 retroperitoneal lymph nodes exhibited intense fluciclovine avidity, whereas one enlarged perirectal lymph node only showed background uptake. Read More

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January 2019
4 Reads

Drug-resistant Enterobacteriaceae colonization is associated with healthcare utilization and antimicrobial use among inpatients in Pune, India.

BMC Infect Dis 2018 Oct 4;18(1):504. Epub 2018 Oct 4.

Byramjee Jeejeebhoy Government Medical College-Johns Hopkins University Clinical Research Site, Pune, Maharashtra, India.

Background: Healthcare exposure may increase drug-resistant Enterobacteriaceae colonization risk. Nascent antimicrobial stewardship efforts in low- and middle-income countries require setting-specific data. We aimed to evaluate risk factors for inpatient drug resistant Enterobacteriaceae colonization in a resource-limited setting in India. Read More

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October 2018
8 Reads

A novel model to correlate hydrogel spacer placement, perirectal space creation, and rectum dosimetry in prostate stereotactic body radiotherapy.

Radiat Oncol 2018 Oct 1;13(1):192. Epub 2018 Oct 1.

Department of Radiation Oncology, Columbia University Medical Center, New York, New York, 10032, USA.

Background: The SpaceOAR hydrogel is employed to limit rectal radiation dose during prostate radiotherapy. We identified a novel parameter - the product of angle θ and hydrogel volume - to quantify hydrogel placement. This parameter predicted rectum dosimetry and acute rectal toxicity in prostate cancer patients treated with stereotactic body radiotherapy to 36. Read More

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October 2018
8 Reads

How frequently are hospitalized patients colonized with carbapenem-resistant Enterobacteriaceae (CRE) already on contact precautions for other indications?

Infect Control Hosp Epidemiol 2018 Dec 1;39(12):1491-1493. Epub 2018 Oct 1.

1Department of Epidemiology,Johns Hopkins University Bloomberg School of Public Health,Baltimore,Maryland.

Using samples collected for VRE surveillance, we evaluated unit admission prevalence of carbapenem-resistant Enterobacteriaceae (CRE) perirectal colonization and whether CRE carriers (unknown to staff) were on contact precautions for other indications. CRE colonization at unit admission was infrequent (3.9%). Read More

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December 2018

Traumatic rectal injuries: Is the combination of computed tomography and rigid proctoscopy sufficient?

J Trauma Acute Care Surg 2018 Dec;85(6):1033-1037

From the Dell Medical School (M.D.T., J.V., C.V.R.B.), University of Texas at Austin, Austin, TX; University of Tennessee Health Science Center (J.P.S., T.M.), Memphis, TN; University of Texas Health Science Center at Houston (J.H.), Houston, TX; University of San Francisco-East Bay (E.B.), Oakland, CA; R. Adams Cowley Shock Trauma Center (B.B.), Baltimore, MD; Vanderbilt University (H.A.H.), Nashville, TN; Methodist Health System (M.T.), Dallas, TX; University of Colorado-Denver Health (C.B.), Denver, CO; University of Southern California (M.S.), Los Angeles, CA; MedStar Washington Hospital Center (J.S.), Washington, DC; Legacy Emmanuel Medical Center (J.V.), Portland, OR; University of Texas Health Science Center San Antonio (B.E.), San Antonio, TX; University of Oklahoma (A.M.C.), Oklahoma City, OK; Harbor-UCLA Medical Center (R.V.), Los Angeles, CA; University of Arizona (G.V.), Tucson, AZ; University of California Davis (E.E.C.), Sacramento, CA; Via Christi Health (J.H.), Wichita, KS; University of California San Diego (R.C.), San Diego, CA; Oregon Health and Science University (P.B.), Portland, OR; East Texas Medical Center (S.G.), Tyler, TX; and Brigham and Women's Hospital (P.G.B.), Boston, MA.

Background: There are no clear guidelines for the best test or combination of tests to identify traumatic rectal injuries. We hypothesize that computed tomography (CT) and rigid proctoscopy (RP) will identify all injuries.

Methods: American Association for the Surgery of Trauma multi-institutional retrospective study (2004-2015) of patients who sustained a traumatic rectal injury. Read More

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December 2018
7 Reads

Practical methods for effective vancomycin-resistant enterococci (VRE) surveillance: experience in a liver transplant surgical intensive care unit.

Infect Control Hosp Epidemiol 2018 Oct 4;39(10):1178-1182. Epub 2018 Sep 4.

1David Geffen School of Medicine at University of California-Los Angeles (UCLA),Los Angeles,California.

Objective: We evaluated the utility of vancomycin-resistant Enterococcus (VRE) surveillance by varying 2 parameters: admission versus weekly surveillance and perirectal swabbing versus stool sampling.

Design: Prospective, patient-level surveillance program of incident VRE colonization.

Setting: Liver transplant surgical intensive care unit (SICU) of a tertiary-care referral medical center with a high prevalence of VRE. Read More

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October 2018

Multimodality Imaging Review of Anorectal and Perirectal Diseases With Histological, Endoscopic, and Operative Correlation, Part I: Anatomy and Neoplasms.

Curr Probl Diagn Radiol 2018 Jul 29. Epub 2018 Jul 29.

Department of Radiology, Louisiana State University Health Shreveport, Shreveport, LA.

A broad spectrum of pathology affects the rectum, anus, and perineum and understanding of its relevant anatomy is important in accurate reporting, particularly in rectal cancer. In this pictorial essay, correlative imaging, endoscopic, pathologic, and operative images are presented to illustrate normal anorectal anatomy and neoplastic conditions that affect the anus and rectum. A particular case-based focus is given to rectal adenocarcinoma with pelvic MR and surgical histopathology. Read More

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July 2018
9 Reads

Multimodality Imaging Review of Anorectal and Perirectal Diseases with Clinical, Histologic, Endoscopic, and Operative Correlation, Part II: Infectious, Inflammatory, Congenital, and Vascular Conditions.

Curr Probl Diagn Radiol 2018 Jul 29. Epub 2018 Jul 29.

Department of Radiology, Louisiana State University Health Shreveport, Shreveport, LA.

A broad spectrum of pathology affects the rectum, anus, and perineum, and multiple imaging modalities are complementary to physical examination for assessment and treatment planning. In this pictorial essay, correlative imaging, endoscopic, pathologic, and operative images are presented for a range of rectal, perirectal, and perineal disease processes, including infectious/inflammatory, traumatic, congenital/developmental, vascular, and miscellaneous conditions. Key anatomic and surgical concepts are discussed, including radiological information pertinent for surgical planning, and current operative approaches of these anatomic spaces to assist radiologists in comprehensive reporting for gastroenterologists and surgeons. Read More

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Benign Anorectal Surgery: Management.

Authors:
Jan Rakinic

Adv Surg 2018 Sep 19;52(1):179-204. Epub 2018 Jun 19.

Department of Surgery, Southern Illinois University School of Medicine, 701 North First Street, Suite D-333, Springfield, IL 62781-0001, USA. Electronic address:

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September 2018
5 Reads

High-dose-rate interstitial brachytherapy as monotherapy in one fraction of 20.5 Gy for the treatment of localized prostate cancer: Toxicity and 6-year biochemical results.

Brachytherapy 2018 Nov - Dec;17(6):845-851. Epub 2018 Jul 18.

Department of Radiation Physics, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain.

Purpose: To evaluate acute and late genitourinary toxicity, the gastrointestinal toxicity, and the long-term biochemical control after high-dose-rate (HDR) monotherapy in one fraction (20.5 Gy).

Materials And Methods: Between May 2011 and October 2014, 60 consecutive patients with low- and intermediate-risk prostate cancer were treated; the median followup was 51 months (range 30-79). Read More

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July 2018
1 Read

Resection of a Perirectal Leiomyosarcoma via a Posterior Transcoccygeal Approach.

Ann Surg Oncol 2018 Sep 6;25(9):2641. Epub 2018 Jul 6.

Department of Surgical Oncology, MD Anderson Cancer Center, Houston, TX, USA.

Introduction: The management of perirectal tumors often requires rectal wall resection, and sometimes a complete proctectomy is required. Access to posterior perirectal masses via a posterior, transcoccygeal approach (Kraske procedure) avoids dissection of the intraperitoneal rectum.

Patient: The patient was a 63-year-old male who presented to his primary care physician with debilitating perirectal pain of several months' duration. Read More

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September 2018
15 Reads

JOURNAL CLUB: Primary Anorectal Melanoma: MRI Findings and Clinicopathologic Correlations.

AJR Am J Roentgenol 2018 Aug 21;211(2):W98-W108. Epub 2018 Jun 21.

2 Department of Pathology, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Republic of Korea.

Objective: The purpose of this study is to evaluate the MRI features of primary anorectal malignant melanoma and to correlate these features with its clinical and pathologic characteristics.

Materials And Methods: The medical records of 12 patients (five men and seven women; mean age [± SD], 60.8 ± 10. Read More

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August 2018
15 Reads

Congenital Perirectal Dermoid Cyst: A Rare Cause of Complex, Recurrent Pediatric Fistula-in-ano.

Front Pediatr 2018 16;6:143. Epub 2018 May 16.

Division of Pediatric Surgery, Children's Hospital Los Angeles, Los Angeles, CA, United States.

Perianal abscess and fistula-in-ano are well-described in the pediatric population. They are most common in infants less than 1 year of age and often resolve with oral antibiotics; occasionally they require drainage or fistulotomy. The etiology is commonly associated with cryptoglandular obstruction and subsequent infection, however alternative diagnoses should be considered in cases of recurrent abscesses and fistulae that are refractory to standard treatments. Read More

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May 2018
5 Reads

Transmission of Clostridium difficile from asymptomatically colonized or infected long-term care facility residents.

Infect Control Hosp Epidemiol 2018 Aug 31;39(8):909-916. Epub 2018 May 31.

6Edward Hines,Jr Veterans Affairs Hospital,Hines,Illinois.

Objective: To test the hypothesis that long-term care facility (LTCF) residents with Clostridium difficile infection (CDI) or asymptomatic carriage of toxigenic strains are an important source of transmission in the LTCF and in the hospital during acute-care admissions.

Design: A 6-month cohort study with identification of transmission events was conducted based on tracking of patient movement combined with restriction endonuclease analysis (REA) and whole-genome sequencing (WGS).

Setting: Veterans Affairs hospital and affiliated LTCF. Read More

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August 2018
5 Reads

Anatomical alterations following the 'PSARP' procedure: Correlating MRI findings with continence scores.

J Pediatr Surg 2018 Apr 27. Epub 2018 Apr 27.

Pediatric Surgery Department, Faculty of Medicine, Ain-Shams University.

Purpose: To identify anatomical aberrations following PSARP procedure by using MRI, while correlating MRI findings to clinical outcome.

Patients And Methods: Between January 2014 and December 2017, we conducted our study on male patients with rectourethral fistula who underwent PSARP. Postoperative pelvic MRI studies were performed and correlated to their clinical continence scores (Rintala, and Krickenbeck classification). Read More

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April 2018
18 Reads

Proctitis and perirectal abscesses: is there anything else to think about?

Rev Esp Enferm Dig 2018 Jun;110(6):410

Radiodiagnóstico, Hospital General Universitario, Ciudad Real.

Lymphogranuloma venereum (LGV) is a condition caused by invasive serovars of Chlamydia trachomatis. The classical inguinal presentation that is characterized by the development of transient genital ulcer(s) and inguinal or femoral lymphadenopathy has decreased in our environment. At present, infection by this bacterium has emerged as an important cause of proctitis and proctocolitis in men who have sex with other men. Read More

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June 2018
2 Reads

Potential Impact of Ga-PSMA-11 PET/CT on the Planning of Definitive Radiation Therapy for Prostate Cancer.

J Nucl Med 2018 Nov 13;59(11):1714-1721. Epub 2018 Apr 13.

Department of Radiation Oncology, UCLA, Los Angeles, California

Standard-of-care imaging for initial staging of prostate cancer (PCa) underestimates disease burden. Prostate-specific membrane antigen (PSMA) PET/CT detects PCa metastasis with superior accuracy, having a potential impact on the planning of definitive radiation therapy (RT) for nonmetastatic PCa. Our objectives were to determine how often definitive RT planning based on standard target volumes covers Ga-PSMA-11 PET/CT-defined disease and to assess the potential impact of Ga-PSMA-11 PET/CT on definitive RT planning. Read More

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November 2018
6 Reads

Improving clinical outcomes for women with overactive bladder or urinary retention symptoms: a comparison of motor response voltages (1-9 V) during Stage 1 sacral neuromodulation.

BJU Int 2018 Sep 17;122(3):472-479. Epub 2018 May 17.

Department of Urology, Detroit Medical Center (DMC), Detroit, MI, USA.

Objective: To assess whether the utilisation of a motor response of <3 V during Stage 1 sacral neuromodulation (SNM) results in better clinical outcomes compared to >4 V in patients with overactive bladder (OAB) or urinary retention symptoms.

Patients And Methods: An observational, retrospective, double cohort review was conducted of 339 female patients who had experienced medically recalcitrant OAB or urinary retention symptoms. Between September 2001 and September 2014, both cohorts underwent successful Stage 1 to Stage 2 SNM placement. Read More

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September 2018
1 Read

Radiotherapy dose-distribution to the perirectal fat space (PRS) is related to gastrointestinal control-related complications.

Clin Transl Radiat Oncol 2017 Dec 6;7:62-70. Epub 2017 Nov 6.

School of Medicine and Public Health, University of Newcastle, New South Wales, Australia.

Traditionally rectal symptoms following pelvic/prostate radiotherapy are correlated to the dosimetry of the anorectum or a substructure of this. It has been suggested that the perirectal fat space (PRS) surrounding the rectum may also be relevant. This study considers the delineation and dosimetry of the PRS related to both rectal bleeding and control-related toxicity. Read More

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December 2017
1 Read

Tuberculous Enteritis Presenting as Acute Appendicitis and Perirectal Abscess.

Case Rep Med 2018 25;2018:6068258. Epub 2018 Feb 25.

Department of Internal Medicine, Section of Infectious Diseases, Virginia Tech Carilion-School of Medicine and Research Institute, Roanoke, VA, USA.

has a wide variety of presentations. A rare occurrence is gastrointestinal tuberculosis. It may occur anywhere along the alimentary canal but usually occurs in the ileocecum with rare involvement of the appendix. Read More

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February 2018
5 Reads

Prospective analysis of hydrogel spacer for patients with prostate cancer undergoing radiotherapy.

BJU Int 2018 Sep 10;122(3):427-433. Epub 2018 Apr 10.

The Austin Hospital, Heidelberg, Vic., Australia.

Objective: To report on the dosimetric benefits and late toxicity outcomes after injection of hydrogel spacer (HS) between the prostate and rectum for patients treated with prostate radiotherapy (RT).

Patients And Methods: In all, 76 patients with a clinical stage of T1-T3a prostate cancer underwent general anaesthesia for fiducial marker insertion plus injection of the HS into the perirectal space before intensity-modulated RT (IMRT) or volumetric-modulated arc RT (VMAT). HS safety, dosimetric benefits, and the immediate- to long-term effects of gastrointestinal (GI) toxicity were assessed. Read More

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September 2018
9 Reads
2 Citations
3.530 Impact Factor

Small Lymph Node Metastasis Detected by 68Ga-Prostate-Specific Membrane Antigen But Not 18F-Fluciclovine PET/CT in Low-Prostate-Specific Antigen Biochemical Recurrence of Prostate Cancer.

Clin Nucl Med 2018 Apr;43(4):250-251

From the Division of Nuclear Medicine, Department of Radiology, McGill University, Montreal, Quebec, Canada.

A 58-year-old man with Gleason 4+3 prostate cancer was initially treated by radical prostatectomy followed by salvage radiotherapy to the prostate bed for postoperative biochemical failure. One year later, F-fluorocholine PET/CT detected a pelvic lymph node recurrence, which was treated with radiation therapy and 6 months of androgen deprivation. PSA started to rise again 18 months later, but F-fluciclovine PET/CT failed to demonstrate the site of recurrence at a PSA of 0. Read More

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April 2018
16 Reads

Comparison of risk factors and outcomes of daptomycin-susceptible and -nonsusceptible vancomycin-resistant Enterococcus faecium infections in liver transplant recipients.

Transpl Infect Dis 2018 Jun 16;20(3):e12856. Epub 2018 Apr 16.

Division of Infectious Diseases & International Health, University of Virginia Health System, Charlottesville, VA, USA.

Background: Vancomycin-resistant Enterococcus faecium (VRE) infections are common in liver transplant recipients (LTRs). Daptomycin (DAP) is an important treatment for such infections; however, DAP-nonsusceptible VRE (DNS-VRE) are increasingly frequent. The purpose of this study was to compare clinical characteristics and outcomes of LTRs with infections due to DNS-VRE and DAP-susceptible VRE (DS-VRE). Read More

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June 2018
6 Reads

Coregistration of Preoperative MRI with Ex Vivo Mesorectal Pathology Specimens to Spatially Map Post-treatment Changes in Rectal Cancer Onto In Vivo Imaging: Preliminary Findings.

Acad Radiol 2018 Jul 19;25(7):833-841. Epub 2018 Jan 19.

Department of Biomedical Engineering, Case Western Reserve University, 309 Wickenden Building, 10900 Euclid Avenue, Cleveland, OH 44106.

Rationale And Objectives: The objective of this study was to develop and quantitatively evaluate a radiology-pathology fusion method for spatially mapping tissue regions corresponding to different chemoradiation therapy-related effects from surgically excised whole-mount rectal cancer histopathology onto preoperative magnetic resonance imaging (MRI).

Materials And Methods: This study included six subjects with rectal cancer treated with chemoradiation therapy who were then imaged with a 3-T T2-weighted MRI sequence, before undergoing mesorectal excision surgery. Excised rectal specimens were sectioned, stained, and digitized as two-dimensional (2D) whole-mount slides. Read More

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July 2018
10 Reads

[Melioidosis is a rare diagnosis among returning travellers with fever].

Ugeskr Laeger 2018 01;180(2)

The causative organism of melioidosis is Burkholderia pseudomallei, a Gram-negative bacterium endemic to Southeast Asia and Northern Australia. The clinical presentation varies, ranging from asymptomatic cases to rapidly progressive septicaemia and shock. Abscesses may be found in any internal organ. Read More

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January 2018
2 Reads

Validation of Active Surveillance Testing for Clostridium difficile Colonization Using the cobas Cdiff Test.

J Clin Microbiol 2018 Apr 26;56(4). Epub 2018 Mar 26.

Department of Laboratory Medicine and Pathology, NorthShore University HealthSystem, Evanston, Illinois, USA

infection (CDI) is not declining in the United States. Nucleic acid amplification tests (NAAT) are used as part of active surveillance testing programs to prevent health care-associated infection. The objective of this study was to validate the cobas Cdiff Test on the cobas 4800 System (cobas) within a four-hospital system using prospectively collected perirectal swabs from asymptomatic patients at admission and during monthly intensive care unit (ICU) screening in an infection control CDI reduction program. Read More

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April 2018
12 Reads

Medical Devices; Radiology Devices; Classification of the Absorbable Perirectal Spacer. Final order.

Authors:

Fed Regist 2018 Jan;83(4):600-2

The Food and Drug Administration (FDA or we) is classifying the absorbable perirectal spacer into class II (special controls). The special controls that apply to the device type are identified in this order and will be part of the codified language for the absorbable perirectal spacer's classification. We are taking this action because we have determined that classifying the device into class II (special controls) will provide a reasonable assurance of safety and effectiveness of the device. Read More

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January 2018

Gastroenteropancreatic-origin neuroendocrine carcinomas: Three case reports with favorable responses following localized radiotherapy and a review of literature.

Medicine (Baltimore) 2017 Dec;96(49):e9009

aDepartment of Radiation OncologybDepartment of Hospital PathologycDivision of Oncology, Department of Internal MedicinedDepartment of Radiology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Rationale: The radiotherapy (RT) responses of gastroenteropancreatic (GEP)-origin neuroendocrine tumors remain unclear. We report cases of favorable response after localized RT of GEP-origin neuroendocrine carcinomas (GEP-NECs).

Patient Concerns: 1. Read More

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December 2017
5 Reads

The bottom line: MRI and CT findings of unusual rectal and perirectal pathology.

Abdom Radiol (NY) 2018 May;43(5):1101-1119

Division of Diagnostic Radiology, Mayo Clinic, 4500 San Pablo Road South, Jacksonville, FL, 32224, USA.

Although common nonspecific symptoms (i.e., rectal bleeding, pelvic pressure, and change in bowel habits) are associated with rectal cancer, occasionally these are related to a different underlying disease. Read More

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May 2018
1 Read

EUS-Guided Transrectal Evacuation of Organized Pelvic Collection Following Roux-en-Y Gastric Bypass After Failure of Radiological and Surgical Approach.

Obes Surg 2018 02;28(2):595-596

Department of Minimally Invasive Digestive Surgery, Antoine-Beclere Hospital, (AP-HP), 92140, Clamart, France.

Introduction: Postoperative collections are an important cause of morbidity following obesity surgery. Surgical revision is most often required if general sepsis is present. Conservative treatment consists of broad spectrum antibiotics and percutaneous drainage of any collection. Read More

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February 2018
4 Reads

Risk Factors and Outcomes Associated with Multidrug-Resistant Acinetobacter baumannii upon Intensive Care Unit Admission.

Antimicrob Agents Chemother 2018 Jan 21;62(1). Epub 2017 Dec 21.

Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA

Multidrug-resistant (MDR) , associated with broad-spectrum antibiotic use, is an important nosocomial pathogen associated with morbidity and mortality. This study aimed to investigate the prevalence of MDR perirectal colonization among adult patients upon admission to the intensive care unit (ICU) over a 5-year period and to identify risk factors and outcomes associated with colonization. A retrospective cohort analysis of patients admitted to the medical intensive care unit (MICU) and surgical intensive care unit (SICU) at the University of Maryland Medical Center from May 2005 to September 2009 was performed using perirectal surveillance cultures on admission. Read More

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January 2018
19 Reads

Ga-PSMA-11 PET/CT Mapping of Prostate Cancer Biochemical Recurrence After Radical Prostatectomy in 270 Patients with a PSA Level of Less Than 1.0 ng/mL: Impact on Salvage Radiotherapy Planning.

J Nucl Med 2018 Feb 9;59(2):230-237. Epub 2017 Nov 9.

Department of Radiation Oncology, UCLA, Los Angeles, California.

Target volume delineations for prostate cancer (PCa) salvage radiotherapy (SRT) after radical prostatectomy are usually drawn in the absence of visibly recurrent disease. Ga-labeled prostate-specific membrane antigen (PSMA-11) PET/CT detects recurrent PCa with sensitivity superior to standard-of-care imaging at serum prostate-specific antigen (PSA) values low enough to affect target volume delineations for routine SRT. Our objective was to map the recurrence pattern of PCa early biochemical recurrence (BCR) after radical prostatectomy with Ga-PSMA-11 PET/CT in patients with serum PSA levels of less than 1 ng/mL, determine how often consensus clinical target volumes (CTVs) based on the Radiation Therapy Oncology Group (RTOG) guidelines cover Ga-PSMA-11 PET/CT-defined disease, and assess the potential impact of Ga-PSMA-11 PET/CT on SRT. Read More

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February 2018
17 Reads

Pathological outcomes in rectal cancer following laparoscopic surgery.

Asia Pac J Clin Oncol 2018 Apr 8;14(2):e175-e180. Epub 2017 Nov 8.

Department of Colorectal Surgery, Concord Repatriation General Hospital, Sydney, NSW, Australia.

Aim: This study examined pathological quality-of-surgery indicators in laparoscopic and open rectal cancer resection specimens.

Methods: Retrospective analysis of consecutive, prospectively recorded laparoscopic (LR) or open (OR) resections for rectal cancer. Indicators included integrity of the perirectal fascial envelope, circumferential margin clearance, lymph node yield and distal margin clearance. Read More

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April 2018
7 Reads

Provider Role in Transmission of Carbapenem-Resistant Enterobacteriaceae.

Infect Control Hosp Epidemiol 2017 11 24;38(11):1329-1334. Epub 2017 Oct 24.

1Department of Public Health Sciences,University of Virginia School of Medicine,Charlottesville,Virginia.

OBJECTIVE We sought to evaluate the role healthcare providers play in carbapenem-resistant Enterobacteriaceae (CRE) acquisition among hospitalized patients. DESIGN A 1:4 case-control study with incidence density sampling. SETTING Academic healthcare center with regular CRE perirectal screening in high-risk units. Read More

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November 2017
1 Read

Calciphylaxis in a nondialysis patient treated with sodium thiosulfate and high dose of oxygen.

Clin Nephrol Case Stud 2017 6;5:38-41. Epub 2017 Jul 6.

Department of Internal Medicine, Bassett Medical Center and Columbia University College of Physicians and Surgeons, Cooperstown, NY, USA, and.

Background: Calciphylaxis in a nondialysis patient is a rare condition and is characterized by calcific deposition in tissue. We present a case of calciphylaxis in a nondialysis patient who was diagnosed by clinical presentation and skin biopsy and was treated with sodium thiosulfate with improvement of skin lesions.

Case: A 43-year-old female with type 2 diabetes and atrial fibrillation taking oral anticoagulation medication presented with reddish drainage from the right buttock. Read More

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July 2017
7 Reads

Inspection of Perirectal Lymph Nodes by One-Step Nucleic Acid Amplification Predicts Lateral Lymph Node Metastasis in Advanced Rectal Cancer.

Ann Surg Oncol 2017 Dec 18;24(13):3850-3856. Epub 2017 Sep 18.

Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita City, Osaka, Japan.

Background: Lateral lymph node dissection (LLND) is performed for advanced rectal cancers in Japan; however, it can cause sexual and urinary dysfunction. The incidence of lateral LN metastasis is estimated at 7-13.9%; therefore, excessive rectal surgery with LLND should be avoided, especially for prophylactic purposes. Read More

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December 2017
16 Reads

Transanal Total Mesorectal Excision: Pneumodissection of Retroperitoneal Structures Eases Laparoscopic Rectal Resection.

Dis Colon Rectum 2017 Oct;60(10):1109-1112

1 Department of Surgery, Rummo Hospital, Benevento, Italy 2 Department of Surgery, San Giovanni Hospital, Rome, Italy.

Introduction: Laparoscopic total mesorectal excision is effective and safe but often technically challenging because of inadequate exposure. Transanal total mesorectal excision was introduced to mitigate this limitation and improve the quality of mesorectal dissection in even the most challenging cases. Currently, the technique for transanal total mesorectal excision dissection is not standardized. Read More

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October 2017
2 Reads

Lymph Node Size on Computed Tomography Images Is a Predictive Indicator for Lymph Node Metastasis in Patients with Colorectal Neuroendocrine Tumors.

In Vivo 2017 Sep-Oct;31(5):1011-1017

Department of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Background: Colorectal neuroendocrine tumors (NET) are a rare manifestation of colorectal neoplasia, requiring for radical dissection of the regional lymph nodes along with colorectal resection similar to that required for colorectal cancer. However, thus far, no reports have described the ability of computed tomography (CT) to predict lymph node involvement. In this study, we revealed the prediction rate of lymph node metastasis using contrast-enhanced CT. Read More

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May 2018
8 Reads

Prediction of lateral pelvic lymph node metastasis from lower rectal cancer using magnetic resonance imaging and risk factors for metastasis: Multicenter study of the Lymph Node Committee of the Japanese Society for Cancer of the Colon and Rectum.

Int J Colorectal Dis 2017 Oct 31;32(10):1479-1487. Epub 2017 Jul 31.

Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Purpose: The goal of the study was to examine prediction of lateral pelvic lymph node (LPLN) metastasis from lower rectal cancer using a logistic model including risk factors for LPLN metastasis and magnetic resonance imaging (MRI) clinical LPLN (cLPLN) status, compared to prediction based on MRI alone.

Methods: The subjects were 272 patients with lower rectal cancer who underwent MRI prior to mesorectal excision combined with LPLN dissection (LPLD) at six institutes. No patients received neoadjuvant therapy. Read More

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October 2017
8 Reads

Minimally Invasive Incision and Drainage Technique in the Treatment of Simple Subcutaneous Abscess in Adults.

Am Surg 2017 Jul;83(7):699-703

A minimally invasive (MI) approach using small incisions and vessel loops for drainage of simple perianal abscesses has been described in the pediatric population with decreased postoperative pain and comparable results to the traditional incision and drainage (I&D). The hypothesis was MI I&D will yield similar outcomes in adults. Patients who underwent I&D of perianal abscesses at an urban hospital from January 2008 to December 2015 were identified by Current Procedural Terminology code. Read More

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July 2017
11 Reads

Anastomotic stricture after ultralow anterior resection or intersphincteric resection for very low-lying rectal cancer.

Surg Endosc 2018 Feb 19;32(2):660-666. Epub 2017 Jul 19.

Department of Surgery, Chonnam National University Hwasun Hospital and Medical School, 322 Seoyang-ro Hwasun-eup, Hwasun-Gun Jeonnam, 58128, Republic of Korea.

Background: Anastomotic stricture following colorectal cancer surgery is not a rare complication, but proper management of anastomotic stricture located close to the anal verge is uncertain. This study aimed to investigate risk factors and management strategies for anastomotic stricture after ultralow anterior resection (ULAR).

Methods: We retrospectively reviewed a database of patients with rectal cancer who underwent surgery between January 2007 and June 2015, and included patients with an anastomosis within 4 cm from the anal verge. Read More

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February 2018
13 Reads

Interval Squamous Cell Carcinoma of the Rectum.

Case Rep Gastroenterol 2017 May-Aug;11(2):396-401. Epub 2017 Jun 19.

Division of Gastroenterology, The Brooklyn Hospital Center - Clinical Affiliate of Mount Sinai Hospital, Brooklyn, New York, USA.

Squamous cell carcinoma (SCC) of the rectum is a rare clinical entity with an incidence rate of 0.1-0.25% per 1,000 cases. Read More

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June 2017
7 Reads

Assessment of Rectal Tumors with Shear-Wave Elastography before Surgery: Comparison with Endorectal US.

Radiology 2017 10 21;285(1):279-292. Epub 2017 Jun 21.

From the Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, the First Affiliated Hospital of Sun Yat-Sen University, 58 Zhongshan Road 2, Guangzhou 510080, People's Republic of China (L.D.C., W.W., J.Y.L., M.D.L., X.Y.X.); Departments of Gastrointestinal Surgery (J.B.X., J.H.C., X.H.Z., H.W., J.N.Y.) and Hepatobiliary Surgery (M.D.L.), the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China; and Department of Epidemiology, Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academic of Medical Science, Guangzhou, China (Z.Q.N.).

Purpose To compare the value of endorectal ultrasonography (US) with shear-wave elastography (SWE) in staging rectal tumors before surgery. Materials and Methods This prospective study was approved by the institutional review board and written informed consent was obtained. In a pilot cohort from April 2015 to January 2016, 70 patients with rectal adenocarcinomas and/or adenomas confirmed with histopathologic examination underwent both endorectal US and SWE. Read More

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October 2017
35 Reads

Sarcomatoid Carcinoma Manifesting as Recurrent Rectal Cancer and Mimicking Radiation-Induced Extraskeletal Osteosarcoma: A Case Report.

Int J Surg Pathol 2017 Dec 20;25(8):732-738. Epub 2017 Jun 20.

2 Konyang University Hospital, Konyang University, Daejeon, Republic of Korea.

Here, we report an unusual case of sarcomatoid carcinoma mimicking extraskeletal osteosarcoma that manifested as recurrent rectal cancer. Five years earlier, a 76-year-old male patient had undergone neoadjuvant chemoradiotherapy followed by a laparoscopic low anterior resection due to adenocarcinoma of the rectum. He was admitted because of pain in the anus and left hip. Read More

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December 2017