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Small 2020 Jul 7:e2000796. Epub 2020 Jul 7.

Department of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China.

Piezoelectric materials can produce electrical power from the mechanical stimulation and thus, they may accelerate electroactive tissue healing as a promising treatment for traumatic peripheral nerve injuries. In this study, a piezoelectric zinc oxide nanogenerator scaffold is manufactured by 3D injectable multilayer biofabrication. The piezoelectric polymeric scaffold displays desirable mechanical and physical characteristics, such as aligned porosity, high elasticity, scaffold stiffness, surface energy, and excellent shear behavior. Read More

Medicine (Baltimore) 2020 Jul;99(27):e20467

Department of Surgery, Trauma Center, Eulji University Hospital, Cheongju, Republic of Korea.

Introduction: In blunt traumatic superficial femoral arterial (SFA) injuries, hemorrhage from the branches without injury to the main artery is rare, but can lead to serious complications, such as compartment syndrome affecting the clinical outcomes. Although open surgical repair has been the standard approach to peripheral vascular injuries, endovascular treatment has become more refined and is now an alternative to open surgery, which potentially involves lower morbidity and mortality rates. However, management of arterial injuries, especially when they involve simple bleeding from small branches of the main artery, can be challenging, and the best treatment options for such injuries remains controversial. Read More

J Vasc Access 2020 Jul 3:1129729820936911. Epub 2020 Jul 3.

Department of Clinical Research Center, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi, PR China.

Objective: Based on the concept of total quality management, the practice of managing needle-stick and sharps injuries was analyzed to improve nursing quality.

Methods: Using total quality management, an improvement plan was completed. Standard operating procedures for infusion therapy and monitoring of the circulatory system were made to reduce the utilization of winged metal needles and the frequency of needle-stick injuries. Read More

Ann Vasc Dis 2020 Jun;13(2):158-162

Section of Pediatric Surgery, The Aga Khan University Hospital, Karachi, Pakistan.

To review the prevalence, pattern, management, outcome, and predictive factors for limb loss of pediatric peripheral arterial injuries (PAIs) at a university hospital in Pakistan. Medical records of children (age <18 years) managed for PAIs at the university hospital between Jan 2008 and Dec 2018 were reviewed for demographic data; mechanism, type, and severity of injury; management; and outcome. During the study period, of the 1718 children managed for trauma, 75 (67 males and 8 females) had PAI secondary to glass cut (33. Read More

Zhonghua Shao Shang Za Zhi 2020 Jun;36(6):419-425

Department of Burns, Zhengzhou First People's Hospital, Zhengzhou 450004, China.

To explore the clinical effect of free anterolateral thigh flap combined with arterial vascular reconstruction on repairing high-voltage electrical burn wound of type Ⅱ and Ⅲ on the wrist. From May 2016 to February 2019, 25 patients with deep high-voltage electrical burn wounds on the wrist were admitted to Zhengzhou First People's Hospital, including 23 males and 2 females, aged 11-63 years. Among them, 4 cases had bilateral electrical burns on the wrist, and 21 cases had unilateral electrical burns on the wrist. Read More

Vascular 2020 Jun 26:1708538120936421. Epub 2020 Jun 26.

Candiolo Cancer Institute FPO-IRCCS, Candiolo, Italy.

Objectives: Somatic mosaicism of gene is currently recognized as the molecular driver of Klippel-Trenaunay syndrome. However, given the limitation of the current technologies, somatic mutations are detected only in a limited proportion of Klippel-Trenaunay syndrome cases and tissue biopsy remains an invasive high risky, sometimes life-threatening, diagnostic procedure. Next generation sequencing liquid biopsy using cell-free DNA has emerged as an innovative non-invasive approach for early detection and monitoring of cancer. Read More

Diagnostics (Basel) 2020 Jun 20;10(6). Epub 2020 Jun 20.

Department of Internal Medicine, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan.

Upstroke time (UT), measured from the foot-to-peak peripheral pulse wave, is a merged parameter used to assess arterial stiffness and target vascular injuries. In this study, we aimed to investigate UT for the prediction of cardiovascular and all-cause mortality in patients with chronic kidney disease (CKD). This longitudinal study enrolled 472 patients with CKD. Read More

J Vasc Nurs 2020 Jun 24;38(2):72-75. Epub 2020 Mar 24.

Division of Vascular and Endovascular Surgery, Department of Surgery, University of Virginia Health System, Charlottesville, Virginia. Electronic address:

Individuals with peripheral arterial disease who have undergone below or above knee amputations have limited mobility and may sit for long periods of time in a wheelchair, increasing their risk for pressure injury. The aim of this descriptive cross-sectional research study was to retrospectively review the charts of those patients with peripheral arterial disease undergoing lower limb amputations from 2016 to 2017 at a major academic medical center to determine the frequency of pressure injury. Hospital data were used to identify patients discharged from 2016 to 2017 with primary International Classification of Diseases (10th Revision) codes for below knee amputations/above knee amputations and pressure injury (ulcer). Read More

Evid Based Complement Alternat Med 2020 18;2020:2162915. Epub 2020 May 18.

Beijing Key Laboratory of Innovative Drug Discovery of Traditional Chinese Medicine (Natural Medicine) and Translational Medicine, Institute of Medicinal Plant Development, Peking Union Medical College and Chinese Academy of Medical Sciences, 100193 Beijing, China.

Objective: Leukopenia, a common complication of tumor chemoradiotherapy, contributes serious damage to the hematopoietic, gastrointestinal, and immune systems of the body and can cause delay, discontinuation, or even failure to tumor treatment, thereby greatly threatening human health. The present study aims to investigate the protective effects of biscoclaurine alkaloids (BA) on leukopenia.

Methods: This study was conducted on 60 Kunming mice, which were randomly divided into six groups containing 10 animals each. Read More

Int J Mol Sci 2020 May 8;21(9). Epub 2020 May 8.

The Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA 24061, USA.

Traumatic brain injuries (TBIs) account for the majority of injury-related deaths in the United States with roughly two million TBIs occurring annually. Due to the spectrum of severity and heterogeneity in TBIs, investigation into the secondary injury is necessary in order to formulate an effective treatment. A mechanical consequence of trauma involves dysregulation of the blood-brain barrier (BBB) which contributes to secondary injury and exposure of peripheral components to the brain parenchyma. Read More

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2020 Apr;42(2):257-262

Department of Vascular Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.

Atherosclerosis (AS) is the main pathological basis for the occurrence of many vascular diseases and has a strong association with metabolic syndrome. Peripheral arterial diseases caused by AS have high morbidities and mortalities but lack still effective treatment. AS animal models are highly valuable for research on peripheral arteriosclerotic diseases. Read More

Bioengineering (Basel) 2020 May 5;7(2). Epub 2020 May 5.

Department of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital Basel, University of Basel, Spitalstrasse 21, 4021 Basel, Switzerland.

Peripheral nerve injuries often result in lifelong disabilities despite advanced surgical interventions, indicating the urgent clinical need for effective therapies. In order to improve the potency of adipose-derived stem cells (ASC) for nerve regeneration, the present study focused primarily on ex-vivo stimulation of ASC by using growth factors, i.e. Read More

Vasc Endovascular Surg 2020 Jul 26;54(5):458-462. Epub 2020 Apr 26.

Division of Vascular and Interventional Radiology, Department of Radiology, University of Minnesota, Minneapolis, MN, USA.

Common femoral artery pseudoaneurysm is a known complication of percutaneous vascular access. Treatment options include surgical repair of the pseudoaneurysm or endovascular methods such as ultrasound-guided compression and direct thrombin injection into the pseudoaneurysm sac. Treatment of pseudoaneurysm is more challenging when a patient is undergoing concurrent catheter-directed or systemic thrombolytic therapy. Read More

Br J Nurs 2020 Apr;29(8):S20-S27

Advanced Nurse Practitioner IV Therapy and Vascular Access, IVAS Lead Nurse, Frimley Health NHS Foundation Trust; Chair, National Infusion and Vascular Access Society (NIVAS).

Vascular access device insertion is a common procedure in healthcare, and complications associated with vascular access can be serious and cause considerable patient harm. The use of care bundles to reduce the risks of these complications is well documented. However, the removal of devices, especially those associated with medical adhesive, can cause significant skin injuries, which often could be avoided if this aspect is included in the care bundle and the risk factors are better understood in healthcare. Read More

PLoS One 2020 6;15(4):e0229530. Epub 2020 Apr 6.

Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG Trauma Center Ludwigshafen, Plastic and Hand Surgery, University of Heidelberg, Heidelberg, Germany.

Background: Peripheral nerve injury in the upper extremity is linked to high socioeconomic burden, yet cost-analyses are rare and from small cohorts. The objective of this study was to determine the costs and long-term socioeconomic effects of peripheral nerve injuries in the upper extremity in Germany.

Methods: We analyzed data of 250 patients with 268 work-related upper extremity nerve injuries from acute treatment to long-term follow-up on rehabilitation, sick-leave and disability-pension. Read More

ACS Nano 2020 05 13;14(5):5298-5313. Epub 2020 Apr 13.

Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.

Stem cell transplantation has been a promising treatment for peripheral arterial diseases in the past decade. Stem cells act as living bioreactors of paracrine factors that orchestrate tissue regeneration. Prestimulated adipose-derived stem cells (ADSCs) have been proposed as potential candidates but have been met with challenges in activating their secretory activities for clinical use. Read More

Neural Regen Res 2020 Sep;15(9):1573-1579

Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.

Vascularization is an important factor in nerve graft survival and function. The specific molecular regulations and patterns of angiogenesis following peripheral nerve injury are in a broad complex of pathways. This review aims to summarize current knowledge on the role of vascularization in nerve regeneration, including the key regulation molecules, and mechanisms and patterns of revascularization after nerve injury. Read More

Hand (N Y) 2020 Feb 28:1558944720906494. Epub 2020 Feb 28.

Vanderbilt University Medical Center, Nashville, TN, USA.

Although intravenous (IV) infiltration is relatively common, data regarding complications and outcomes of this problem remain limited. In addition, there is wide variation in institutional protocols for the management of IV infiltrations. Through retrospective review, we aim to delineate complications and outcomes, and propose an algorithm for the management of these injuries. Read More

JBJS Rev 2020 Jan;8(1):e0051

Department of Orthopedic Surgery, Cleveland Clinic, Cleveland, Ohio.

Background: Vascular injuries associated with total knee arthroplasty can have limb and life-threatening consequences. The aims of this study were to conduct a meta-analysis of the overall rate of vascular injuries after total knee arthroplasty and to conduct a systematic review of specific major and minor vessel injuries.

Methods: All English-language literature published from January 1, 1998, to November 30, 2018, was queried in 4 unique databases using a common search term. Read More

Am J Pathol 2020 03 21;190(3):630-641. Epub 2020 Feb 21.

John A. Moran Eye Center, University of Utah, Salt Lake City, Utah. Electronic address:

The investigation of erythropoietin (EPO) has expanded to include potential nonhematopoietic roles in neural and retinal diseases, including diabetic retinopathy. However, it remains unclear how EPO functions to support the neural retina. Transgenic mice with hypoactive EPO receptor (EPOR) signaling (hWtEPOR) were compared with littermate control mice (WT) to test the role of EPOR signaling under normal conditions and after vascular injury and regrowth into the retina. Read More

Eur J Vasc Endovasc Surg 2020 Jun 20;59(6):929-938. Epub 2020 Feb 20.

Division of Vascular Surgery, "Vita - Salute" San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.

Objective: The aim of this study was to assess the feasibility and safety of percutaneous axillary access with vessel closure device closure after puncturing the first segment during endovascular treatment of complex aneurysms with fenestrated and branched endografts (F/BEVAR).

Methods: The PAXA (Percutaneous AXillary Access) study is a physician initiated, single centre, ambispective, non-randomised study (clinicaltrials.gov: NCT03223311). Read More

Unfallchirurg 2020 Mar;123(3):225-237

Unfallchirurgische Abteilung, Landeskrankenhaus Salzburg, Paracelsus Medizinische Universität, Salzburg, Österreich.

Lesions of peripheral nerves substantially influence the long-term prognosis and functional outcome. Approximately 70% of peripheral nerval lesions are associated with vascular injuries and occur more frequently with certain fractures and osteosynthesis types. The prognosis and treatment depend on the severity of the injury and the presence of axonal lesions, in particular, determines the further procedure. Read More

Vascular 2020 Feb 17:1708538120903960. Epub 2020 Feb 17.

Department of Radiology, Osmangazi University Medical School, Eskisehir, Turkey.

Objectives: To evaluate the primary patency rate at three years for the infra-aortic peripheral arterial pathologies treated with polytetrafluoroethylene-covered stent-grafts.

Methods: Patients treated with self-expandable polytetrafluoroethylene-covered stent-grafts for infra-aortic peripheral arterial aneurysms, pseudo-aneurysms, and arterio-venous fistulas were evaluated retrospectively. A total of 48 patients (35 male, 13 female; mean age: 53. Read More

Chin J Traumatol 2020 Feb 25;23(1):5-9. Epub 2019 Dec 25.

Department of Vascular Surgery, Beijing Jishuitan Hospital, Beijing 100035, China.

Traumatic peripheral vascular injury is a significant cause of disability and death either in civilian environments or on the battlefield. Penetrating trauma and blunt trauma are the most common forms of vascular injuries. Besides, iatrogenic arterial injury (IAI) is another pattern of vascular trauma. Read More

Am Fam Physician 2020 02;101(3):159-166

St. Luke's University Health Network, Bethlehem, PA, USA.

Chronic wounds are those that do not progress through a normal, orderly, and timely sequence of repair. They are common and are often incorrectly treated. The morbidity and associated costs of chronic wounds highlight the need to implement wound prevention and treatment guidelines. Read More

Muscle Nerve 2020 04 13;61(4):E28-E30. Epub 2020 Feb 13.

Neurology Unit, AOUI Verona, Italy.

J Trauma Acute Care Surg 2020 Apr;88(4):469-476

From the Trauma Service (J.M.P., J.M.V.G., R.Y.C., K.D.C., L.E.W., M.J.S., C.B.S., V.B., M.J.M.), Scripps Mercy Hospital; and Division of Pediatric Surgery (J.M.P., R.C.I.), Rady Children's Hospital, San Diego, California.

Background: Extremity vascular injuries in children are rare events that present unique therapeutic challenges. The absence of a pediatric-specific protocol for definitive care of these injuries risks variability in treatment practices and outcomes. Using a nationwide data set, we investigated variations in the management and outcomes of pediatric patients with peripheral vascular trauma and characterized differences based on hospital category. Read More

Adv Skin Wound Care 2020 Feb;33(2):76-83

PhD Candidate, School of Nursing, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia Joint Appointment, School of Nursing, Faculty of Health, Queensland University of Technology, Clinical Nurse, Skin Integrity Service, Royal Brisbane & Women's Hospital, Brisbane, Queensland, Australia Lecturer, School of Nursing, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia Professor of Nursing, Joint Appointment, School of Nursing, Queensland University of Technology, Royal Brisbane & Women's Hospital, Visiting Professor, Institute for Skin Integrity and Infection Prevention, University of Huddersfield, West Yorkshire, England.

General Purpose: To present a systematic review of the literature conducted to define and extend knowledge of the risk factors, causes, and antecedent conditions of acute skin failure (ASF) in adult intensive care patients.

Target Audience: This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care.

Learning Objectives/outcomes: After participating in this educational activity, the participant should be better able to:1. Read More

Expert Rev Med Devices 2020 Feb;17(2):111-122

Department of Radiology, UT Southwestern Medical Center, Dallas, Texas, USA.

: MR neurography (MRN) of the brachial plexus has emerged in recent years as a safe and accurate modality for the identification of brachial plexopathies in pediatric and adult populations. While clinical differentiation of brachial plexopathy from cervical spine-related radiculopathy or nerve injury has long relied upon nonspecific physical exam and electrodiagnostic testing modalities, MRN now permits detailed interrogation of peripheral nerve anatomy and pathology, as well as assessment of surrounding soft tissues and musculature, thereby facilitating accurate diagnosis. The reader will learn about the current state of brachial plexus MRN, including recent advances and future directions, and gain knowledge about the adult and pediatric brachial plexopathies that can be characterized using these techniques. Read More

Zhonghua Gan Zang Bing Za Zhi 2019 11;27(11):899-902

Department of Vascular Intervention, Affiliated Nanhua Hospital of Nanhua University, Hengyang 421002, China.

BMC Nephrol 2020 Jan 14;21(1):15. Epub 2020 Jan 14.

Schulich School of Medicine, Medical Sciences Building Room M101, Western University, London, ON, N6A 5C1, Canada.

Background: Patients with chronic kidney disease are at higher risk of developing cardiovascular disease. Chronic exposure to intermittent hemodialysis may be a source of added stress to the cardiovascular system; intradialytic hypotension is a common complication of hemodialysis, and repeated events may lead to hemodynamic stress and ischemic injuries. Administration of non-pneumatic compression stockings to the lower limbs has demonstrated hemodynamic stabilizing effects in other settings and may provide similar benefits in the kidney disease population. Read More

Am J Infect Control 2020 Jan 10. Epub 2020 Jan 10.

School of Nursing and Midwifery, Griffith University, Brisbane, Australia; Alliance for Vascular Access Teaching & Research (AVATAR) Group, Menzies Health Institute Queensland, Griffith University, Brisbane, Australia.

Background: Needleless connectors (NCs) were introduced to reduce health care work needlestick injuries (NSIs). If not decontaminated prior to use, NCs can be a portal for patient blood stream infections. The optimal disinfectant, and its application duration, for NC decontamination has not been empirically established. Read More

Inj Prev 2020 Jan 8. Epub 2020 Jan 8.

Institute for Health Metrics and Evaluation, University of Washington, Seattle, Washington, USA.

Background: The global burden of road injuries is known to follow complex geographical, temporal and demographic patterns. While health loss from road injuries is a major topic of global importance, there has been no recent comprehensive assessment that includes estimates for every age group, sex and country over recent years.

Methods: We used results from the Global Burden of Disease (GBD) 2017 study to report incidence, prevalence, years lived with disability, deaths, years of life lost and disability-adjusted life years for all locations in the GBD 2017 hierarchy from 1990 to 2017 for road injuries. Read More

Plast Reconstr Surg 2020 01;145(1):161-164

Albuquerque, N.M. From the Division of Plastic, Reconstructive and Burn Surgery, University of New Mexico.

Posttraumatic hand injuries from crush injury, infusion, or iatrogenic vascular cannulation can cause ischemic finger damage that can progress to necrosis and digital amputation. Botulinum toxin type A (Botox) improves blood flow in chronic vasospastic disorders of the hand. Botox's efficacy in salvaging ischemic loss in digits in acute traumatic and iatrogenic injury has not been previously reported. Read More

Int J Mol Sci 2019 Dec 23;21(1). Epub 2019 Dec 23.

Third-Grade Pharmacological Laboratory on Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges University, Yichang 443002, China.

Cerebral ischemia injury, the leading cause of morbidity and mortality worldwide, initiates sequential molecular and cellular pathologies that underlie ischemic encephalopathy (IE), such as ischemic stroke, Alzheimer disease (AD), Parkinson's disease (PD), epilepsy, etc. Targeted therapeutic treatments are urgently needed to tackle the pathological processes implicated in these neurological diseases. Recently, accumulating studies demonstrate that microRNA-124 (miR-124), the most abundant miRNA in brain tissue, is aberrant in peripheral blood and brain vascular endothelial cells following cerebral ischemia. Read More

BMC Surg 2019 Dec 21;19(1):198. Epub 2019 Dec 21.

Department of Urology, First Affiliated Hospital of Dalian Medical University, 116011, Zhongshan Road No, Dalian, 222, China.

Background: This retrospective clinical study is to evaluate the safety and efficiency of two different approaches in retroperitoneal laparoscopic adrenalectomy and provide experience and basis for the treatment of adrenal tumors through retroperitoneal approach.

Methods: From July 2015 to February 2018, 112 patients with adrenal lesions underwent retroperitoneal laparoscopic adrenalectomy (RLA) using a 3-port method. Among them, 56 patients underwent RLA via the extra perinephric fat approach (EPFA), 56 patients underwent RLA via the intra perinephric fat approach (IPFA). Read More

Ann Vasc Surg 2020 Jul 16;66:225-232. Epub 2019 Dec 16.

Department of Vascular Surgery, Turku University Hospital and University of Turku, Turku, Finland.

Background: Patient injury claim data and insurance records constitute detailed sources of information on patient injuries and their contributing or causal factors. This study aimed to identify the unintended incidents that lead to patient injuries in vascular surgery in the treatment of peripheral arterial disease (PAD) in Finland.

Methods: The records of all accepted patient injury claims involving PAD between 2004 and 2017 inclusive were obtained from the nationwide Finnish Patient Insurance Centre registry and were reviewed. Read More

Biomed Res Int 2019 16;2019:8520523. Epub 2019 Nov 16.

Division of Urology, Department of Surgery, Cardinal Tien Hospital, New Taipei City, Taiwan.

Radical prostatectomy causes erectile dysfunction (ED) and irreversible morphologic changes, including induction of endothelial and smooth muscle cell (SMC) apoptosis in the corpus cavernosum (CC). The injection of smooth muscle progenitor cells (SPCs) thickens the vascular intima and has demonstrated therapeutic benefit in cardiovascular disease animal. Herein, we investigated the effect of SPCs on the recovery of erectile function (EF) in rat models with bilateral cavernous nerve (CN) injury. Read More

J Clin Med 2019 Dec 2;8(12). Epub 2019 Dec 2.

Unistra, Translational Medicine federation of Strasbourg (FMTS), Faculty of Medicine, Team 3072 «Mitochondria, Oxidative Stress and Muscle Protection», 11 rue Humann, 67000 Strasbourg, France.

Peripheral arterial disease (PAD) is a frequent and serious condition, potentially life-threatening and leading to lower-limb amputation. Its pathophysiology is generally related to ischemia-reperfusion cycles, secondary to reduction or interruption of the arterial blood flow followed by reperfusion episodes that are necessary but also-per se-deleterious. Skeletal muscles alterations significantly participate in PAD injuries, and interestingly, muscle mitochondrial dysfunctions have been demonstrated to be key events and to have a prognosis value. Read More

Acta Cir Bras 2019 28;34(9):e201900901. Epub 2019 Nov 28.

Full Professor, Urogenital Research Unit, UERJ, Rio de Janeiro-RJ, Brazil. Critical revision, final approval.

Purpose: To evaluate the effects of tadalafil (TD) in preventing histological alterations of the corpus cavernosum caused by isolated lesions of cavernous nerve (ILCN) and artery (ILCA) in rats.

Methods: Fifty male Wistar rats were randomly assigned in five groups: G1: control; G2: bilateral ILCN; G3: bilateral ILCA; G4: ILCN+TD; G5: ILCA+TD. The cavernous bodies were submitted to histomorphometry, immunohistochemistry and biochemical analysis. Read More

Clin Orthop Relat Res 2019 Dec;477(12):2761-2768

C. Chuaychoosakoon, P. Suwanno, T. Boonriong, S. Suwannaphisit, P. Klabklay, W. Parinyakhup, K. Maliwankul, B. Tangtrakulwanich, Department of Orthopaedic Surgery and Physical Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand Y. Duangnumsawang, Faculty of Veterinary Science, Prince of Songkla University, Songkhla, Thailand.

Background: Fixation of clavicle shaft fractures with a plate and screws can endanger the neurovascular structures if proper care is not taken. Although prior studies have looked at the risk of clavicular plates and screws (for example, length and positions) to vulnerable neurovascular structures (such as the subclavian vein, subclavian artery, and brachial plexus) in the supine position, no studies to our knowledge have compared these distances in the beach chair position.

Questions/purposes: (1) In superior and anteroinferior plating of midclavicle fractures, which screw tips in a typical clavicular plating approach place the neurovascular structures at risk of injury? (2) How does patient positioning (supine or beach chair) affect the distance between the screws and the neurovascular structures?

Methods: The clavicles of 15 fresh-frozen cadavers were dissected. Read More

J Pak Med Assoc 2019 11;69(11):1758

Department of Surgery, Aga Khan University Hospital, Karachi Pakistan.

J Pharmacol Sci 2019 Dec 4;141(4):131-138. Epub 2019 Nov 4.

Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, 54 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.

Oxaliplatin, a platinum-based chemotherapeutic drug, frequently induces peripheral neuropathy. Accumulating evidences suggest a possible relationship between peripheral vascular impairment and peripheral neuropathy. In this study, we investigated the effects of vasodilators on cumulative peripheral neuropathy induced by repeated injections of oxaliplatin (10 mg/kg) once a week for 8 weeks in mice. Read More

J Vasc Surg 2020 01 11;71(1):252-254. Epub 2019 Nov 11.

Department of Vascular Surgery, Maasstad Hospital, Rotterdam, The Netherlands.

Critical ischemia in the upper extremity is rare. A surgical bypass is thought to be the superior treatment option. We describe a rare case where regular tunneling options of the bypass were not available and an intramedullary tunnel was used. Read More

J Endovasc Ther 2020 02 14;27(1):102-108. Epub 2019 Nov 14.

Department of Internal Medicine, Division of Cardiology, Shimonoseki City Hospital, Yamaguchi, Japan.

To evaluate a new scoring balloon, the non-slip element (NSE) percutaneous transluminal angioplasty (PTA) balloon, in the treatment of femoropopliteal lesions by comparing angiographic dissection patterns to those of a conventional balloon. This retrospective, single-center study included 71 symptomatic patients (mean age 77.4±8. Read More

J Orthop Surg Res 2019 Nov 12;14(1):359. Epub 2019 Nov 12.

Department of Neurosurgery-Neuro Critical Care, UT Health San Antonio, San Antonio, TX, USA.

Background: Socio-demographic factors have been suggested to contribute to differences in healthcare utilization for several elective orthopedic procedures. Reports on disparities in utilization of orthopedic trauma procedures remain limited. The purpose of our study is to assess the roles of clinical and socio-demographic variables in utilization of operative fixation of calcaneus fractures in the USA. Read More

Neurologist 2019 Nov;24(6):176-179

Neurocritical Care Unit, Ohio State University Wexner Medical Center, Columbus, OH.

Background: Central venous catheters are often used to administer hypertonic saline (HTS) but might be associated with serious complications. Intraosseous (IO) access is an alternative method of medication and fluid delivery which is not associated with life-threatening complications and can be inserted faster than CVCs.

Methods: A prospective case series was conducted on critically ill neurological patients that did not have central venous access, and for whom 3% HTS was indicated. Read More

Anesthesiol Clin 2019 Dec 17;37(4):593-607. Epub 2019 Sep 17.

Department of Anesthesiology and Pain Management, UT Southwestern Medical Center, Mail Code 9068, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

Thoracic endovascular aneurysm repair (TEVAR) is fast becoming the primary treatment of thoracic aortic aneurysms, thoracic aortic dissections, acute aortic injuries, and other conditions affecting the thoracic aorta. Patients scheduled for TEVAR tend to have a host of comorbid conditions, including coronary artery disease, diabetes, and chronic obstructive pulmonary disease. Intraoperative management should optimize end-organ perfusion, facilitate neuromonitoring, and adjust hemodynamic management. Read More

Foot (Edinb) 2019 Sep 20;40:109-115. Epub 2019 Aug 20.

NYU Langone Medical Center, United States; NYU Langone Brooklyn-Chief of Podiatry, United States.

The use of single photon emission computer tomography (SPECT/CT) in acute vascular injury is not well documented. SPECT/CT combines the anatomic detail of computer tomography with the functional vascular perfusion of photon emission to determine the viability of osseous structures and surrounding soft tissue. The superimposed imaging provides the practitioner with a reliable anatomic image of viability of a specific anatomic area following insult or injury. Read More