543 results match your criteria Perioral Dermatitis

Glucocorticoids Promote CCL20 Expression in Keratinocytes.

Br J Dermatol 2021 Jun 22. Epub 2021 Jun 22.

Department of Dermatology, University of California San Diego, La Jolla, California, 92093, USA.

Glucocorticoids (GC) are generally envisioned as immunosuppressive, but in conditions such as rosacea and perioral dermatitis they can lead to increased skin inflammation. In lung epithelia, GC promote expression of the pro-inflammatory cytokine CCL20, which contributes to steroid-resistant asthma. In the skin, CCL20 stimulates inflammation by recruiting Th17 T-lymphocytes and dendritic cells and is elevated in papulopustular rosacea. Read More

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Topical Steroid-Induced Perioral Dermatitis (TOP STRIPED): Case Report of a Man Who Developed Topical Steroid-Induced Rosacea-Like Dermatitis (TOP SIDE RED).

Cureus 2021 Apr 12;13(4):e14443. Epub 2021 Apr 12.

Dermatology, San Diego Family Dermatology, National City, USA.

The long-term use of topical corticosteroids can result in rosacea-like dermatitis or facial perioral dermatitis. The case of a 54-year-old man is described who developed topical corticosteroid-induced perioral dermatitis (TOP STRIPED), and the features of topical corticosteroid-induced rosacea-like dermatitis are reviewed. The man presented with a painful erythematous facial eruption. Read More

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Self-case report of oral and skin lesions associated with positivity of COVID-19.

J Cosmet Dermatol 2021 May 15. Epub 2021 May 15.

Department of Prosthetic Dentistry, Faculty of Medicine and Dentistry, Palacky University, Olomouc, Czech Republic.

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Predictive Model for Differential Diagnosis of Inflammatory Papular Dermatoses of the Face.

Ann Dermatol 2020 Aug 30;32(4):298-305. Epub 2020 Jun 30.

Department of Dermatology, Seoul National University Bundang Hospital, Seongnam, Korea.

Background: The clinical features of inflammatory papular dermatoses of the face are very similar. Their clinical manifestations have been described on the basis of a small number of case reports and are not specific.

Objective: This study aimed to use computer-aided image analysis (CAIA) to compare the clinical features and parameters of inflammatory papular dermatoses of the face and to develop a formalized diagnostic algorithm based on the significant findings. Read More

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Role of Adenosine Deaminase in Patients with Erythematotelangiectatic Rosacea and Positivity.

Iran J Parasitol 2020 Oct-Dec;15(4):596-601

Department of Medical Microbiology, Faculty of Medicine, Giresun University, Giresun, Turkey.

Background: Adenosine deaminase (ADA) is an aminohydrolase involved in the catabolism of purine nucleotides and irreversibly deaminizes adenosine and deoxyadenosine to inosine and deoxyinosine. ADA enzyme deficiency results in the loss of functional properties of B and T lymphocytes. species have been reported to be transmitted between humans through close contact and to play a role in the pathogenesis of rosacea, acne vulgaris, perioral dermatitis, seborrhoeic dermatitis, micropapillary-pruritic dermatitis and blepharitis. Read More

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Perioral dermatitis: diagnosis, proposed etiologies and management.

J Cosmet Dermatol 2021 Mar 9. Epub 2021 Mar 9.

Department of Dermatology, Aalborg University Hospital, Aalborg, Denmark.

Perioral dermatitis is a common cutaneous condition characterized by acneiform facial eruptions often with an eczematous appearance. A granulomatous subtype exists in addition to the classic variant. Whilst topical corticosteroids have been largely implicated in this condition, its etiology is not completely understood. Read More

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The "Maskne" microbiome - pathophysiology and therapeutics.

Wan-Lin Teo

Int J Dermatol 2021 Jul 12;60(7):799-809. Epub 2021 Feb 12.

TWL Specialist Skin & Laser Centre, Singapore.

"Maskne" is a new term coined during the 2020 COVID-19 pandemic. It refers to a subset of acne mechanica, deserving consideration in view of widespread reusable fabric mask-wearing to control the pandemic worldwide. Understanding of underlying pathophysiology directly relates to the novel skin microenvironment and textile-skin friction created by mask-wearing, distinct from nontextile-related acne mechanica previously linked to wearing of headgear. Read More

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Mask-induced Koebner phenomenon and its clinical phenotypes: A multicenter, real-life study focusing on 873 dermatological consultations during COVID-19 pandemics.

Dermatol Ther 2021 Mar 8;34(2):e14823. Epub 2021 Feb 8.

Department of Health Sciences, University of Eastern Piedmont, Novara, Italy.

During COVID-19 pandemic, wearing masks for prevention became mandatory but evidence suggest that is also detrimental for skin. Although facial dermatoses due to masks increase in both healthcare workers and general population, a pathogenetic hypothesis remains still elusive. We aimed to evaluate the prevalence of dermatological consultations due to Koebner triggered dermatoses In this prospective, multicenter, real life study carried out in Italy from March 11th to December 11th 2020 during COVID-19 pandemics, dermatological consultations (in-person and telemedicine) to study the prevalence of Koebner (KB) phenomenon due to masks were evaluated. Read More

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Acta Clin Croat 2020 Jun;59(2):318-328

1Department of Dermatovenereology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2School of Dental Medicine, University of Zagreb, Zagreb, Croatia; 3Faculty of Dental Medicine and Health, Josip Juraj Strossmayer University of Osijek, Osijek, Croatia; 4Department of Oral Medicine, School of Dental Medicine, University of Zagreb, Zagreb, Croatia.

Allergic reactions sometimes participate in the development of perioral and oral diseases, indicating the need for appropriate allergen assessment. This review discusses current knowledge on the potential allergic reactions to different dental materials in patients with oral and perioral diseases. Aside from allergies to various dental materials, similar non-allergic, non-immune contact reactions (irritant or toxic) can occur. Read More

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Childhood granulomatous periorificial dermatitis: case report and review of the literature.

Dermatol Online J 2020 Dec 15;26(12). Epub 2020 Dec 15.

Queen Fabiola Children's University Hospital, Faculty of Medicine, Université Libre de Bruxelles, Brussels.

Childhood granulomatous periorificial dermatitis (CGPD), considered a clinical variant of perioral dermatitis, typically affects prepubertal children of African descent. It is a condition of unknown etiology characterized by the presence of a monomorphic yellow-brown papular eruption limited to the perioral, perinasal, and periocular regions that histopathologically shows a granulomatous pattern. This disorder should be differentiated from other conditions as granulomatous rosacea, sarcoidosis, and lupus miliaris disseminatus faciei. Read More

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December 2020

The Effect of Volatile Oil from Chinese Mugwort Leaf on Human Demodecid Mites In Vitro.

Acta Parasitol 2021 Jun 4;66(2):615-622. Epub 2021 Jan 4.

Department of Medical Parasitology, Wannan Medical College, Wuhu, 241002, Anhui, China.

Background: Human demodecid mites including Demodex folliculorum and Demodex brevis Akbulatova can cause acne, rosacea, epifolliculitis, blepharitis, seborrheic dermatitis, perioral dermatitis, acromastitis and such skin health problems. Artemisia (Composiate) are widely distributed in temperate regions in the northern hemisphere. It has been reported that 17 species of plants in Artemisia used to be mugwort in China. Read More

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Treatment of pediatric periorificial dermatitis with topical calcineurin inhibitor and topical/oral metronidazole.

J Dermatol 2021 Mar 4;48(3):405-407. Epub 2020 Dec 4.

Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.

Pediatric periorificial dermatitis is a papulopustular eruption found around the facial orifices in children. Although the treatment of the disease has been largely anecdotal and experience-based, studies have shown that topical calcineurin inhibitors, as well as other topical and oral antibiotics, such as metronidazole, can be effective treatment options. However, most of the studies with a sizable number of patients have been based on the Caucasian population. Read More

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Recurrent Facial Rash.

Jason Ramirez

Am Fam Physician 2020 11;102(10):625-626

University of Maryland School of Medicine, Baltimore, MD, USA.

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November 2020

Phytochemical constituents, biological activities, and health-promoting effects of the genus Origanum.

Phytother Res 2021 Jan 12;35(1):95-121. Epub 2020 Aug 12.

Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Origanum species are mostly distributed around the Mediterranean, Euro-Siberian, and Iran-Siberian regions. Since time immemorial, the genus has popularly been used in Southern Europe, as well as on the American continent as a spice now known all over the world under the name "oregano" or "pizza-spice." Origanum plants are also employed to prepare bitter tinctures, wines, vermouths, beer, and kvass. Read More

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January 2021

The basics of baggy eyelids.

Dis Mon 2020 Oct 1;66(10):101037. Epub 2020 Jul 1.

Department of Ophthalmology and Visual Science, University of Chicago, Chicago, IL, United States; Department of Surgery, Northshore University HealthSystem, 2050 Pfingsten Rd., Ste. 280, Glenview, Evanston 60026, IL, United States. Electronic address:

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October 2020

Rosacea and perioral dermatitis: a single-center retrospective analysis of the clinical presentation of 1032 patients.

J Dtsch Dermatol Ges 2020 Jun 29;18(6):561-570. Epub 2020 May 29.

Department of Dermatology and Allergy, Hospital of the Ludwig Maximilian University of Munich, Munich, Germany.

Background: Rosacea is a common chronic inflammatory cutaneous disorder affecting nearly 5.5 % of the adult population. Our aim was to evaluate the prevalence and epidemiology of rosacea and perioral dermatitis (POD) in an ambulatory care setting. Read More

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Doxycycline, an Antibiotic or an Anti-Inflammatory Agent? The Most Common Uses in Dermatology.

Actas Dermosifiliogr (Engl Ed) 2020 Sep 13;111(7):561-566. Epub 2020 May 13.

Unidad de Dermatología Médico-Quirúrgica y Venereología, Hospital Universitario San Cecilio, Granada, España.

Doxycycline is a synthetic tetracycline that was approved in 1967. This wide-spectrum antibiotic has been shown to also have useful anti-inflammatory properties that make it suitable for the treatment of a number of noninfectious conditions. Tetracyclines are probably the most commonly prescribed antibiotics in dermatology, where they are usually used at doses lower than those effective against infections. Read More

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September 2020

Perioral phytophotodermatitis induced by parsnip mash.

Contact Dermatitis 2020 Oct 15;83(4):318-319. Epub 2020 Jun 15.

Dermatology Department, Le Havre Hospital, Le Havre, 76600, France.

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October 2020

A Practical Approach to Recalcitrant Face and Neck Dermatitis in Atopic Dermatitis.

Dermatitis 2020 May/Jun;31(3):169-177

Northwestern University Feinberg School of Medicine.

Face and neck dermatitis in the atopic dermatitis patient is a diagnostically challenging entity with broad differential diagnoses. Recent case reports reporting face and neck dermatitis in patients on dupilumab therapy have added further complexity to diagnosis and management. Herein, we discuss a broad diagnostic algorithm and practical management strategy for recalcitrant face and neck dermatitis in the atopic patient with an emphasis on face and neck dermatitis associated with dupilumab therapy. Read More

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Granulomatous Periorificial Dermatitis in an Adult: A case report with review of literature.

Sultan Qaboos Univ Med J 2020 Feb 9;20(1):e100-e103. Epub 2020 Mar 9.

Department of Dermatology, Al Nahdha Hospital, Muscat, Oman.

Granulomatous periorificial dermatitis (GPD) is a benign, self-limiting eruption that is considered a clinical variant of periorificial dermatitis, also known as perioral dermatitis. It presents primarily in prepubertal children as monomorphic scaly papules over perioral, paranasal and periorbital areas of the face with rare occurrence in adults. We report a 36-year-old Omani male patient who presented to the Dermatology Clinic at Bahla Polyclinic, Bahla, Oman, in 2018 with a papular eruption over his face for the previous six months. Read More

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February 2020

Excellent response to oral clarithromycin in a patient with severe childhood granulomatous periorificial dermatitis with neck involvement.

J Dermatol 2020 Jun 18;47(6):e222-e224. Epub 2020 Mar 18.

Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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Intractable Chronic Granulomatous Perioral Dermatitis in Patients Receiving Growth Hormone Therapy: A New Association between CGPD and GH.

Indian J Dermatol 2020 Mar-Apr;65(2):139-140

Department of Dermatology, Seoul National University Bundang Hospital, Gyeonggi-do, Korea.

Childhood granulomatous periorificial dermatitis (CGPD) is a self-limiting skin condition characterized by papular eruptions around the mouth, nose and eyes of preadolescent children. We report two cases of intractable CGPD in which patients receiving growth hormone (GH) therapy showed persistent symptoms despite multiple treatment modalities. This association may suggest the role of GH in the pathogenesis of CGPD. Read More

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Topical calcineurin inhibitors for pediatric periorificial dermatitis.

J Am Acad Dermatol 2020 Jun 4;82(6):1409-1414. Epub 2020 Feb 4.

Division of Dermatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Background: Data regarding the treatment of periorificial dermatitis with topical calcineurin inhibitors (TCI) in the pediatric population are limited.

Objective: To assess the clinical utility of TCI in pediatric patients with periorificial dermatitis.

Methods: A retrospective medical record review of all pediatric patients with periorificial dermatitis treated with TCIs was performed. Read More

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A pediatric recalcitrant case of perioral dermatitis successfully treated with topical 0.03% tacrolimus alone.

Dermatol Ther 2020 03 12;33(2):e13253. Epub 2020 Feb 12.

Department of dermatology, Ahi Evran University, Kırşehir, Turkey.

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[Staphylococcal scalded skin syndrome in a pediatric patient with atopic dermatitis].

Arch Argent Pediatr 2020 02;118(1):e30-e33

Servicio de Pediatría, Hospital General Universitario de Ciudad Real, España.

The staphylococcal scalded skin syndrome is a rare dermatological entity that in early stages may be confused with a flare-up of a rush of atopic dermatitis. We present the case of an 8-year-old boy with a history of atopic dermatitis and egg allergy that went to the Emergency Department for erythematous-bullous lesions on the skin. Symptoms began as an erythema in areas of flexures, which associated conjunctivitis and bilateral eyelid erythema. Read More

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February 2020

Human Orf: An Under-recognized Entity.

Acta Dermatovenerol Croat 2019 Dec;27(4):280-281

Luis Santiago, MD, Dermatology Department Centro Hospitalar e Universitário de Coimbra, Praceta Prof. Mota Pinto, 3000-075 Coimbra, Portugal;

Dear Editor, Orf, also called contagious ecthyma, contagious pustular dermatitis, sore mouth, or scabby mouth, is a highly contagious zoonotic disease which is caused by a double-stranded DNA virus, ORFV (Parapoxvirus genus of the family Poxviridae) (1). The infection is endemic to sheep and goats, and humans are infected either through direct transmission from active lesions on infected animals or through contact with fomites (2). Orf is an occupational hazard and the population at risk includes shepherds, butchers, farmers, wool shearers, and veterinarians (2,3). Read More

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December 2019

Flushing at Sites of Topical Tacrolimus Application Induced by Drinking Alcohol.

Dermatitis 2020 May/Jun;31(3):e23-e24

University of Pittsburgh School of Medicine The University of Texas Southwestern, Dallas. Department of Dermatology The University of Texas Southwestern, Dallas. North Texas Veterans Affairs Medical Center, Dallas.

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Efficacy of a skin care cream with TRPV1 inhibitor 4-t-butylcyclohexanol in the topical therapy of perioral dermatitis.

J Cosmet Dermatol 2020 Jun 29;19(6):1409-1414. Epub 2019 Oct 29.

Department of Dermatology and Allergy, Ludwig-Maximilian University, Munich, Germany.

Background: Perioral dermatitis is a clinically distinctive reaction pattern of facial dermatitis, including redness, dryness, burning, pruritus and skin tightness. A gold standard treatment remains unclear.

Objectives: Our study evaluates the clinical value of a skin care cream with the transient receptor potential vanilloid type 1 inhibitor 4-t-butylcyclohexanol in POD patients over 8 weeks. Read More

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