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    1082 results match your criteria Perioperative Medication Management

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    Inhaled pulmonary vasodilator therapy for management of right-ventricular dysfunction after left ventricular assist device placement and cardiac transplantation.
    Pharmacotherapy 2017 May 24. Epub 2017 May 24.
    Clinical Pharmacy Manager, Heart Transplant and Mechanical Circulatory Support; NewYork-Presbyterian Hospital, Columbia University Medical Center, Department of Pharmacy, New York, NY.
    Right ventricular failure (RVF) after cardiac transplant (CTX) or implantation of a continuous-flow left ventricular assist device (CF-LVAD) is associated with significant post-operative morbidity and mortality. A variety of modalities have been used to treat post-operative RVF, including management of volume status, intravenous inotropes and vasodilators, and right-sided mechanical support. Inhaled vasodilator agents are a unique treatment option aimed at minimizing systemic absorption by delivering therapy directly to the pulmonary vasculature. Read More

    Spinal analgesia improves surgical outcome after open nephrectomy for renal cell carcinoma: a randomized controlled study.
    Scand J Urol 2017 May 22:1-5. Epub 2017 May 22.
    b Department of Urology and Andrology , Umeå University , Umeå , Sweden.
    Objective: This study evaluated whether more effective perioperative analgesia can be part of a multimodal approach to minimizing morbidity and improving postoperative management after the open surgical approaches frequently used in the treatment of renal cell carcinoma (RCC). The aim of the study was to determine whether spinal anesthesia with clonidine can enhance postoperative analgesia, speed up mobilization and reduce the length of hospital stay (LOS).

    Materials And Methods: Between 2012 and 2015, 135 patients with RCC were randomized, in addition to general anesthesia, to receive either spinal analgesia with clonidine or epidural analgesia, stratified to surgical technique. Read More

    Perioperative Management of Rheumatoid Medications in Orthopedic Surgery.
    Orthopedics 2017 May 20:1-5. Epub 2017 May 20.
    Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disorder known to cause progressive joint destruction. Over time, untreated RA can lead to pain and increasing disability, making orthopedic intervention necessary. The treatment of RA revolves around a variety of medications that blunt the overall immune response. Read More

    Effect of high-dose sodium selenite in cardiac surgery patients: A randomized controlled bi-center trial.
    Clin Nutr 2017 May 2. Epub 2017 May 2.
    Department for Anesthesia, Intensive Care Medicine and Rescue Medicine, Lucerne Cantonal Hospital, Lucerne, Switzerland; Department of Anesthesiology and Intensive Care Medicine, Hirslanden Clinic, Zürich, Switzerland. Electronic address:
    Background & Aims: Cardiac surgery is accompanied by oxidative stress and systemic inflammatory response, which may be associated with organ dysfunction and increased mortality. Selenium and selenoenzymes are important constituents of anti-oxidative defense. We hypothesized that high-dose sodium selenite supplementation can attenuate the postoperative inflammation and might, therefore, improve clinical outcome. Read More

    Anesthesia and perioperative pain management during cardiac electronic device implantation.
    J Pain Res 2017 19;10:927-932. Epub 2017 Apr 19.
    Laboratory for Pain Research, University of Split School of Medicine.
    Background: The degree of pain caused by the implantation of cardiac electronic devices (CEDs) and the type of anesthesia or perioperative pain management used with the procedure have been insufficiently studied. The aim of this study was to analyze perioperative pain management, as well as intensity and location of pain among patients undergoing implantation of CED, and to compare the practice with published guidelines.

    Patients And Methods: This was a combined retrospective and prospective study conducted at the tertiary hospital, University Hospital Split, Croatia. Read More

    In patients undergoing lung resection is it safe to administer amiodarone either as prophylaxis or treatment of atrial fibrillation?
    Interact Cardiovasc Thorac Surg 2017 May;24(5):783-788
    Department of Thoracic Surgery, Guy's Hospital, London, UK.
    A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was whether the administration of amiodarone is safe in patients undergoing lung resection either for prophylaxis or treatment of de novo postoperative atrial fibrillation (POAF). A total of 30 papers were identified, of which 13 represented the best evidence to answer the clinical question. Read More

    American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) joint consensus statement on optimal analgesia within an enhanced recovery pathway for colorectal surgery: part 1-from the preoperative period to PACU.
    Perioper Med (Lond) 2017 13;6. Epub 2017 Apr 13.
    Division of General, Vascular and Transplant Anesthesia, Duke University Medical Center, Durham, USA.
    Background: Within an enhanced recovery pathway (ERP), the approach to treating pain should be multifaceted and the goal should be to deliver "optimal analgesia," which we define in this paper as a technique that optimizes patient comfort and facilitates functional recovery with the fewest medication side effects.

    Methods: With input from a multi-disciplinary, international group of clinicians, and through a structured review of the literature and use of a modified Delphi method, we achieved consensus surrounding the topic of optimal analgesia in the perioperative period for colorectal surgery patients.

    Discussion: As a part of the first Perioperative Quality Improvement (POQI) workgroup meeting, we sought to develop a consensus document describing a comprehensive, yet rational and practical, approach for developing an evidence-based plan for achieving optimal analgesia, specifically for a colorectal surgery ERP. Read More

    American Society for Enhanced Recovery (ASER) and Perioperative Quality Initiative (POQI) Joint Consensus Statement on Optimal Analgesia within an Enhanced Recovery Pathway for Colorectal Surgery: Part 2-From PACU to the Transition Home.
    Perioper Med (Lond) 2017 13;6. Epub 2017 Apr 13.
    Division of General, Vascular and Transplant Anesthesia, Duke University Medical Center, Durham, UK.
    Background: Within an enhanced recovery pathway (ERP), the approach to treating pain should be multifaceted and the goal should be to deliver "optimal analgesia", which we define in this paper as a technique that optimizes patient comfort and facilitates functional recovery with the fewest medication side effects.

    Methods: With input from a multidisciplinary, international group of experts and through a structured review of the literature and use of a modified Delphi method, we achieved consensus surrounding the topic of optimal analgesia in the perioperative period for colorectal surgery patients.

    Discussion: As a part of the first Perioperative Quality Improvement (POQI) workgroup meeting, we sought to develop a consensus document describing a comprehensive, yet rational and practical, approach for developing an evidence-based plan for achieving optimal analgesia, specifically for a colorectal surgery within an ERP. Read More

    New-onset postoperative atrial fibrillation after aortic valve replacement: Effect on long-term survival.
    J Thorac Cardiovasc Surg 2017 Mar 12. Epub 2017 Mar 12.
    Department of Cardiology, St Antonius Hospital, Nieuwegein, The Netherlands.
    Objective: There is a paucity of data on long-term survival of new-onset postoperative atrial fibrillation (POAF) after cardiac surgery. Also, mean follow-up in previous studies is confined to a maximum of one decade. This retrospective, longitudinal cohort study was performed to determine the effect on long-term survival of new-onset POAF after aortic valve replacement (AVR) over a mean follow-up of almost 2 decades. Read More

    A Contemporary Medicolegal Analysis of Implanted Devices for Chronic Pain Management.
    Anesth Analg 2017 Apr;124(4):1304-1310
    From the *Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and †CRICO Strategies, Boston, Massachusetts.
    Background: Analysis of closed malpractice claims allows the study of rare but serious complications and likely results in improved patient safety by raising awareness of such complications. Clinical studies and closed claims analyses have previously reported on the common complications associated with intrathecal drug delivery systems (IDDS) and spinal cord stimulators (SCS). This study provides a contemporary analysis of claims from within the past 10 years. Read More

    Hemodynamic and perioperative management in two different preclinical pig-to-baboon cardiac xenotransplantation models.
    Xenotransplantation 2017 Mar 5. Epub 2017 Mar 5.
    Department of Anaesthesiology, Ludwig Maximilian University, Munich, Germany.
    Background: The perioperative phase of preclinical cardiac xenotransplantations significantly affects the experimental outcome. Moderate or even severe hemodynamic and respiratory impairment occurs frequently in baboons after receiving a cardiac transplant. The perioperative management of such postoperative instability is very demanding, especially in the experimental setting. Read More

    Peroral endoscopic myotomy: procedural complications and pain management for the perioperative clinician.
    Med Devices (Auckl) 2017 23;10:53-59. Epub 2017 Feb 23.
    Department of Anesthesiology.
    Achalasia refers to the lack of smooth muscle relaxation of the distal esophagus. Although nonsurgical treatments such as pneumatic dilatation of the distal esophagus and botulinum toxin injections have been performed, these procedures have limited duration. Similarly, surgical treatment with Heller myotomy is associated with complications. Read More

    Proper Management of Medications to Limit Errors: What the Oral Surgeon Should Know to Limit Medication Errors and Adverse Drug Events.
    Oral Maxillofac Surg Clin North Am 2017 May 1;29(2):141-149. Epub 2017 Mar 1.
    Private Practice, Eastern Iowa Oral and Maxillofacia Surgery, 835 3rd Avenue Southeast, Cedar Rapids, IA 52403, USA.
    Providing safe and effective ambulatory anesthesia is a key component in delivering optimal care to oral and maxillofacial patients. Unfortunately, medication errors and adverse drug events (ADEs) occur in offices, as they do in hospital operating rooms. Preparing and delivering medication seems simple. Read More

    A comparison of the postoperative analgesic efficacy between epidural and intravenous analgesia in major spine surgery: a meta-analysis.
    J Pain Res 2017 14;10:405-415. Epub 2017 Feb 14.
    Department of Orthopedics, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, Shanghai, People's Republic of China.
    Postoperative analgesia remains a challenge for orthopedic surgeons. The aim of this meta-analysis is to compare the efficacy of epidural analgesia (EA) and intravenous patient-controlled analgesia (IV-PCA) following major spine surgery. We searched electronic databases, including the PubMed, EMBASE, Ovid and Cochrane databases, for randomized controlled trials (RCTs) published before June 2016. Read More

    Is pain at discharge a risk factor for unplanned hospital readmission?
    Acta Clin Belg 2017 Apr 23;72(2):95-102. Epub 2017 Feb 23.
    a Ghent University Hospital, (Strategic) Policy Cell , Ghent , Belgium.
    Introduction: Unplanned readmissions are associated with a high cost to health insurances and the incidence of preventable readmissions could be considered as a quality indicator for the initial hospital admission. We aimed to assess the predictive value for unplanned readmission of higher pain scores at discharge of the initial admission as well as of other pain and demographic characteristics. The documentation of significant associations would provide further support for a structured pain management policy. Read More

    Surgical management for achalasia after coronary artery bypass graft using the right gastroepiploic artery: a case report.
    Surg Case Rep 2017 Dec 14;3(1):27. Epub 2017 Feb 14.
    Department of General Surgical Science, Gunma University Graduate School of Medicine, Gunma University, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan.
    Background: The right gastroepiploic artery is commonly used in coronary artery bypass grafting. Appropriate strategies are required when performing upper abdominal surgeries after the right gastroepiploic artery has been used in coronary artery bypass grafting because compressing or injuring the graft may cause myocardial ischemia and fatal arrhythmias. To our knowledge, this is the first reported case of surgery for achalasia performed after coronary artery bypass grafting using the right gastroepiploic artery. Read More

    Targeting urine output and 30-day mortality in goal-directed therapy: a systematic review with meta-analysis and meta-regression.
    BMC Anesthesiol 2017 Feb 10;17(1):22. Epub 2017 Feb 10.
    Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
    Background: Oliguria is associated with a decreased kidney- and organ perfusion, leading to organ damage and increased mortality. While the effects of correcting oliguria on renal outcome have been investigated frequently, whether urine output is a modifiable risk factor for mortality or simply an epiphenomenon remains unclear. We investigated whether targeting urine output, defined as achieving and maintaining urine output above a predefined threshold, in hemodynamic management protocols affects 30-day mortality in perioperative and critical care. Read More

    Unused Opioid Pills After Outpatient Shoulder Surgeries Given Current Perioperative Prescribing Habits.
    Am J Sports Med 2017 Mar 9;45(3):636-641. Epub 2017 Feb 9.
    Anesthesiology/Critical Care Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
    Background: In the past 16 years, the number of prescription opioids sold in the United States, as well as deaths from prescription opioids, has nearly quadrupled. However, the overall amount of pain reported by patients has not changed significantly. Specific information about opioid prescriptions in the perioperative period is lacking. Read More

    Hemodynamic profile and behavioral characteristics during induction of anesthesia in pediatric patients with attention deficit hyperactivity disorder.
    Paediatr Anaesth 2017 Apr 8;27(4):417-424. Epub 2017 Feb 8.
    Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.
    Aim: There is no consensus regarding the administration of stimulant drugs preoperatively, particularly in pediatric patients diagnosed with ADHD. The primary objective of the current study was to assess differences in blood pressure and heart rate before and after induction of anesthesia between patients on chronic amphetamine or methylphenidate therapy who receive their normal dose preoperatively compared to patients in whom the prescribed medication was withheld. Secondary objectives were to assess the anxiety level during the induction of anesthesia and the effect of premedication with midazolam. Read More

    Analysis of perioperative pain management in vascular surgery indicates that practice does not adhere with guidelines: a retrospective cross-sectional study.
    J Pain Res 2017 17;10:203-209. Epub 2017 Jan 17.
    Laboratory for Pain Research, University of Split School of Medicine, Split, Croatia.
    Background: Inadequate treatment of pain related to surgery may be associated with complications and prolonged recovery time and increased morbidity and mortality rates. We investigated perioperative pain management in vascular surgery and compared it with the relevant guidelines for the treatment of perioperative pain.

    Methods: We conducted a retrospective study on 501 patients who underwent vascular surgery at the University Hospital Split, Croatia. Read More

    Perioperative Hemodynamic Instability and Fluid Overload are Associated with Increasing Acute Kidney Injury Severity and Worse Outcome after Cardiac Surgery.
    Blood Purif 2017 31;43(4):298-308. Epub 2017 Jan 31.
    Research and Science Administration of Medical School Brandenburg (MHB), Brandenburg an der Havel, Germany.
    Purpose: The study aimed to investigate patients' characteristics, fluid and hemodynamic management, and outcomes according to the severity of cardiac surgery-associated acute kidney injury (CSA-AKI).

    Methods: In a single-center, prospective cohort study, we enrolled 282 adult cardiac surgical patients. In a secondary analysis, we assessed preoperative patients' characteristics, physiological variables, and medication for intra- and postoperative fluid and hemodynamic management and outcomes according to CSA-AKI stages by the Renal risk, Injury, Failure, Loss, End-stage renal disease (RIFLE) classification. Read More

    Validation of the scale on Satisfaction of Adolescents with Postoperative pain management - idiopathic Scoliosis (SAP-S).
    J Pain Res 2017 11;10:137-143. Epub 2017 Jan 11.
    Pediatric Complex Pain Team, IWK Health Centre; Department of Anesthesia, Pain Management, and Perioperative Medicine, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada.
    Background: Spinal fusion is a common orthopedic surgery in children and adolescents and is associated with high pain levels postoperatively. If the pain is not well managed, negative outcomes may ensue. To our knowledge, there is no measure in English that assesses patient's satisfaction with postoperative pain management following idiopathic scoliosis surgery. Read More

    [A Case of Thyroid Carcinoma in Consideration for Perioperative Management].
    Gan To Kagaku Ryoho 2016 Nov;43(12):2124-2126
    Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.
    When patients are on long-term dialysis, various kinds of medication are given. We report our experience with a 75-yearold woman with thyroid carcinoma incidentally discovered during dialysis. Ultrasonography of the thyroid showed a tumor of about 3 cm in the right lobe center. Read More

    Patients With Type 2 Diabetes: Anesthetic Management in the Ambulatory Setting: Part 2: Pharmacology and Guidelines for Perioperative Management.
    Anesth Prog 2017 ;64(1):39-44
    Assistant Professor, Department of Dental Anesthesiology, University of Pittsburgh School of Dental Medicine, Pittsburgh, Pennsylvania.
    Type 2 diabetes is a disease of metabolism in which the afflicted patient cannot properly utilize carbohydrates, fats, and proteins. Because the prevalence of type 2 diabetes is rapidly increasing throughout the general population, anesthesia providers must realize that a significant percentage of their patients will present with the disease. Anesthesia providers should have an intimate knowledge of the comorbidities and complications that are associated with type 2 diabetes and know the specific pharmacokinetics and pharmacodynamics of the drugs used to treat the disease. Read More

    Analysis of Incident and Accident Reports and Risk Management in Spine Surgery.
    Spine (Phila Pa 1976) 2017 Jan 16. Epub 2017 Jan 16.
    *Department of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai Showa-ward, Aichi, Nagoya 466-8550; Japan †Department of Quality and Patient Safety, Nagoya University Hospital, 65 Tsurumai Showa-ward, Aichi, Nagoya 466-8550; Japan.
    Study Design: A review of accident and incident reports.

    Objective: To analyze prevalence, characteristics, and details of perioperative incidents and accidents in patients receiving spine surgery.

    Summary Of Background Data: In our institution, a clinical error that potentially results in an adverse event is usually submitted as an incident or accident report through a web database, to ensure anonymous and blame-free reporting. Read More

    Medication Overuse in Chronic Pain.
    Curr Pain Headache Rep 2017 Jan;21(1)
    Comprehensive Pain Center, Department of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
    Purpose Of Review: Chronic pain is usually managed by various pharmacotherapies after exhausting the conservative modalities such as over-the-counter choices. The goal of this review is to investigate current state of opioids and non-opioid medication overuse that includes NSAIDs, skeletal muscle relaxants, antidepressants, membrane stabilization agents, and benzodiazepine. How to minimize medication overuse and achieve better outcome in chronic pain management?

    Recent Findings: Although antidepressants and membrane stabilization agents contribute to the crucial components for neuromodulation, opioids were frequently designated as a rescue remedy in chronic pain since adjunct analgesics usually do not provide instantaneous relief. Read More

    [Neuraxial anaesthesia and NOACs].
    Med Klin Intensivmed Notfmed 2017 Mar 10;112(2):111-116. Epub 2017 Jan 10.
    Klinik für Anästhesie, Operative Intensiv- u. Palliativmedizin, Städtisches Klinikum Solingen gGmbH, Gotenstraße 1, 42653, Solingen, Deutschland.
    Background: Cardiovascular comorbidities in surgical patients are frequent and have a substantial impact on the postoperative outcome. Neuraxial blockades are able to reduce perioperative morbidity and mortality. The increasing use of new oral anticoagulants (NOAC) requires a high level of attention, especially in patients undergoing neuraxial blockades or requiring postoperative analgesia. Read More

    Long-Term Outcomes in the Management of Painful Diabetic Neuropathy.
    Can J Neurol Sci 2017 Jan 9:1-6. Epub 2017 Jan 9.
    1Department of Clinical Neurological Sciences,Western University,London,Canada.
    Background: Painful diabetic neuropathy (PDN) is a frequent complication of diabetes mellitus. Current treatment recommendations are based on short-term trials, generally of ≤3 months' duration. Limited data are available on the long-term outcomes of this chronic disease. Read More

    Constrictive Pericarditis: A Practical Clinical Approach.
    Prog Cardiovasc Dis 2017 Jan - Feb;59(4):369-379. Epub 2017 Jan 4.
    Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA. Electronic address:
    Constrictive pericarditis (CP) represents a form of severe diastolic heart failure (HF), secondary to a noncompliant pericardium. The true prevalence of CP is unknown but it is observed in 0.2-0. Read More

    Organ transplantation and drug eluting stents: Perioperative challenges.
    World J Transplant 2016 Dec;6(4):620-631
    Aparna Dalal, Department of Anesthesiology, Icahn School of Medicine, New York, NY 10029, United States.
    Patients listed for organ transplant frequently have severe coronary artery disease (CAD), which may be treated with drug eluting stents (DES). Everolimus and zotarolimus eluting stents are commonly used. Newer generation biolimus and novolimus eluting biodegradable stents are becoming increasingly popular. Read More

    Non-opioid pain management in benign minimally invasive hysterectomy: A systematic review.
    Am J Obstet Gynecol 2016 Dec 30. Epub 2016 Dec 30.
    Department of Obstetrics and Gynecology, University of Michigan Women's Hospital, Ann Arbor, MI.
    Background: Less postoperative pain typically is associated with a minimally invasive hysterectomy compared with a laparotomy approach; however, poor pain control can still be an issue. Multiple guidelines exist for managing postoperative pain, yet most are not specialty-specific and are based on procedures that bear little relevance to a minimally invasive hysterectomy.

    Objective: The purpose of this study was to determine whether there is enough quality evidence within the benign gynecology literature to make non-opioid pain control recommendations for women who undergo a benign minimally invasive hysterectomy. Read More

    Medication safety in the operating room: literature and expert-based recommendations.
    Br J Anaesth 2017 Jan 30;118(1):32-43. Epub 2016 Dec 30.
    Department of Anesthesiology, University of Tennessee College of Medicine, Memphis, TN, USA.
    Human error poses significant risk for hospitalized patients causing an estimated 100,000 to 400,000 deaths in the USA annually. Medication errors contribute, with error occurring in 5.3% of medication administrations during surgery. Read More

    Multicentre survey on the current surgical management of oesophageal atresia in Belgium and Luxembourg.
    J Pediatr Surg 2017 Feb 14;52(2):239-246. Epub 2016 Nov 14.
    Department of Paediatric Surgery/Gastro-intestinal Surgery, Princess Elisabeth Children's Hospital, Ghent University Hospital, Ghent, Belgium.
    Introduction: The surgical management of oesophageal atresia (OA) differs between pediatric surgical teams without consensus. We aimed to describe the current practice of OA treatment in Belgium and Luxembourg and compare this to the literature.

    Materials And Methods: A questionnaire was created and sent to all 18 hospitals (14 pediatric surgical units) performing OA surgery in Belgium and Luxembourg. Read More

    Refractory status epilepticus in children with and without prior epilepsy or status epilepticus.
    Neurology 2017 Jan 23;88(4):386-394. Epub 2016 Dec 23.
    From the Division of Epilepsy and Clinical Neurophysiology, Department of Neurology (I.S.F., M.C.J., M.G.L., K.K., T.L.), and Division of Critical Care, Departments of Neurology, Anesthesiology, Perioperative and Pain Medicine (R.C.T.), Boston Children's Hospital, Harvard Medical School, MA; Department of Child Neurology (I.S.F.), Hospital Sant Joan de Déu, Universidad de Barcelona, Spain; Division of Neurology (N.S.A., A.A.T.), The Children's Hospital of Philadelphia, The Perelman School of Medicine at the University of Pennsylvania; Cincinnati Children's Hospital Medical Center (R.A., T.A.G., K.P.), University of Cincinnati, OH; Department of Neurology and Pediatrics (J.N.B., H.P.G.), The University of Virginia Health System, Charlottesville; Department of Epilepsy, Neurophysiology, and Critical Care Neurology (J.L.C., W.D.G.), Children's National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC; Departments of Pediatrics and Neurology (K.E.C.), Children's Hospital Colorado, University of Colorado School of Medicine, Aurora; Universidad Austral de Chile (M.G.L.), Valdivia, Chile; Ruth D. & Ken M. Davee Pediatric Neurocritical Care Program (J.L.G., M.S.W.), Northwestern University Feinberg School of Medicine, Chicago, IL; Division of Pediatric Neurology (A.H., M.A.M.), Duke University Medical Center, Duke University, Durham, NC; Division of Child Neurology (T.L.M., J.R.), Department of Neurology, Columbia University Medical Center, Columbia University, New York, NY; Section of Neurology and Developmental Neuroscience (A.W.), Department of Pediatrics, Baylor College of Medicine, Houston, TX; Barrows Neurological Institute (K.W.), Phoenix Children's Hospital; Department of Pediatrics (K.W.), University of Arizona School of Medicine, Tucson; and Department of Neurology (K.W.), Mayo Clinic, Scottsdale, AZ.
    Objective: To compare refractory convulsive status epilepticus (rSE) management and outcome in children with and without a prior diagnosis of epilepsy and with and without a history of status epilepticus (SE).

    Methods: This was a prospective observational descriptive study performed from June 2011 to May 2016 on pediatric patients (1 month-21 years of age) with rSE.

    Results: We enrolled 189 participants (53% male) with a median (25th-75th percentile) age of 4. Read More

    [Operation key points and efficacy evaluation of Jinling procedure for mixed refractory constipation].
    Zhonghua Wei Chang Wai Ke Za Zhi 2016 Dec;19(12):1329-1334
    Research Institute of General Surgery, Jinling Hospital, Nangjing 210002, China.
    For chronic transit constipation (STC), surgery should be considered when all pharmacological interventions, biofeedback, and sacral nerve stimulation failed to relieve severe symptoms. Chronic functional constipation can be subdivided into three subtypes: colonic slow-transit constipation, outlet obstruction and mixed refractory constipation. The pathological changes of colonic slow transit and outlet obstruction constipation can influence each other. Read More

    Association of Perioperative Statin Use With Mortality and Morbidity After Major Noncardiac Surgery.
    JAMA Intern Med 2017 Feb;177(2):231-242
    Department of Biostatistics, University of Colorado, Denver6Adult and Child Center for Outcomes Research and Delivery Science (ACCORDS) and Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora.
    Importance: The efficacy of statins in reducing perioperative cardiovascular and other organ system complications in patients undergoing noncardiac surgery remains controversial. Owing to a paucity of randomized clinical trials, analyses of large databases may facilitate informed hypothesis generation and more efficient trial design.

    Objective: To evaluate associations of early perioperative statin use with outcomes in a national cohort of veterans undergoing noncardiac surgery. Read More

    Is Laparoendoscopic Single-Site Adrenalectomy a Feasible Alternative in Treating Aldosterone-Producing Adenoma?
    Biomed Res Int 2016 16;2016:6894381. Epub 2016 Nov 16.
    Department of Surgery, Taipei Tzuchi Hospital, The Buddhist Tzu Chi Medical Foundation, Taipei, Taiwan; Department of Urology, Tzu Chi University, Medical College, Hualien, Taiwan.
    Objective. To compare laparoendoscopic single-site (LESS) and conventional multiport adrenalectomy in patients with aldosterone-producing adenoma (APA). Material and Methods. Read More

    Is standardized care feasible in the emergency setting? A case matched analysis of patients undergoing laparoscopic cholecystectomy.
    BMC Surg 2016 Dec 1;16(1):78. Epub 2016 Dec 1.
    Department of Visceral Surgery, University Hospital CHUV, Bugnon 46, 1011, Lausanne, Switzerland.
    Background: Immediate laparoscopic cholecystectomy is the accepted standard for the treatment of acute cholecystitis. The aim of the present study was to evaluate the feasibility of a standardized approach with tailored care maps for pre- and postoperative care by comparing pain, nausea and patient satisfaction after elective and emergent laparoscopic cholecystectomy.

    Methods: From January 2014 until April 2015, data on pain and nausea management were prospectively recorded for all elective and emergency procedures in the department of visceral surgery. Read More

    Intravenous Amisulpride for the Prevention of Postoperative Nausea and Vomiting: Two Concurrent, Randomized, Double-blind, Placebo-controlled Trials.
    Anesthesiology 2017 Feb;126(2):268-275
    From the Department of Anesthesiology, Stony Brook University Medical Center, Stony Brook, New York (T.J.G.); Department of Anaesthesia and Critical Care, University Hospitals of Würzburg, Würzburg, Germany (P.K.); Department of Anesthesiology, Memorial Hermann Memorial City Hospital, Houston, Texas (H.S.M.); Department of Anesthesiology, Wexner Medical Center at The Ohio State University, Columbus, Ohio (S.D.B.); Department of Anesthesiology, Universitätsklinikum Heidelberg, Heidelberg, Germany (J.M.); Department of Anaesthesiology and Intensive Care, Philipps University Marburg, Marburg, Germany (L.E.); Department of Anesthesiology, Christus St John Hospital, Nassau Bay, Texas (D.G.L.); Department of Anesthesiology, Helen Keller Hospital, Sheffield, Alabama (T.I.M.); Service d'Anesthésie, Hôpital Mère Enfant, Bron, France (D.C.); Department of Anesthesiology, University of Kansas Medical Center, Kansas City, Kansas (A.L.K.); Department of Anesthesiology, Pain Management and Perioperative Medicine, University of Miami, Miller School of Medicine, Miami, Florida (K.A.C.); Clinical Development Department, Acacia Pharma Ltd, Cambridge, United Kingdom (G.F.); and Department of Anesthesiology and Intensive Care, University Hospital of Hautepierre, Strasbourg, France (P.D.).
    Background: Two essentially identical, randomized, double-blind, placebo-controlled, parallel-group phase III studies evaluated the efficacy of intravenous amisulpride, a dopamine D2/D3 antagonist, in the prevention of postoperative nausea and vomiting in adult surgical patients.

    Methods: Adult inpatients undergoing elective surgery during general anesthesia and having at least two of the four Apfel risk factors for postoperative nausea and vomiting were enrolled at 9 U.S. Read More

    The Role of the Perioperative Nurse in Improving Surgical Patients' Clinical Outcomes and Satisfaction: Beyond Medication.
    AORN J 2016 Dec;104(6S):S17-S22
    For the perioperative nurse, the management of postsurgical pain includes various responsibilities, such as performing postsurgical pain assessments as an essential first step, facilitating recovery from surgery, and maximizing patient satisfaction during the postsurgical period. In addition, nurses are responsible for providing patient education regarding pain management, the quality of which may strongly influence patient satisfaction. External and internal challenges exist in perioperative care processes, however, and addressing these challenges will promote the overall goal of providing high-quality care. Read More

    Lifetime prevalence of and factors associated with non-traumatic musculoskeletal pains amongst surgeons and patients.
    Int Orthop 2017 Jan 18;41(1):31-38. Epub 2016 Nov 18.
    Department of Surgery and Perioperative Care, Dell Medical School, The University of Texas at Austin, 1400 Barbara Jordan Blvd. Suite 2.834; MC: R1800, Austin, TX, 78723, USA.
    Purpose: There is evidence that surgeons make different recommendations for people seeking their care than they make for themselves. There may also be differences in pain episodes and management strategies between surgeons and people seeking care, knowledge of which might improve care. We aimed to assess whether the prevalence of non-traumatic pains, treatments and other factors differed between patients and surgeons. Read More

    Pre-treatment clinical assessment in head and neck cancer: United Kingdom National Multidisciplinary Guidelines.
    J Laryngol Otol 2016 May;130(S2):S13-S22
    Department of Anaesthesia,Freeman Hospital,Newcastle upon Tyne NHS Foundation Trust,Newcastle upon Tyne,UK.
    This is the official guideline endorsed by the specialty associations involved in the care of head and neck cancer patients in the UK. This paper provides recommendations on the pre-treatment clinical assessment of patients presenting with head and neck cancer. Recommendations • Comorbidity data should be collected as it is important in the analysis of survival, quality of life and functional outcomes after treatment as well as for comparing results of different treatment regimens and different centres. Read More

    Factors Associated with Patient-Initiated Telephone Calls After Spine Surgery.
    World Neurosurg 2017 Feb 10;98:625-631. Epub 2016 Nov 10.
    Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, USA. Electronic address:
    Background: Telephone calls play a significant role in the follow-up care of postoperative patients. However, further data are needed to identify the determinants of patient-initiated telephone calls after surgery because these factors may also highlight potential areas of improvement in patient satisfaction and during the hospital discharge process. Therefore, the goal of this study is to determine the number of postoperative patient telephone calls within 14 days after surgery and establish the factors associated with patient-initiated calls and reasons for calling. Read More

    Intranasal Medication Administration Using a Squeeze Bottle Atomizer Results in Overdosing if Deployed in Supine Patients.
    Anesth Analg 2016 Nov 8. Epub 2016 Nov 8.
    From the *Department of Anesthesiology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, Pennsylvania; and †the Department of Anesthesiology, Perioperative Medicine, and Pain Management, Miller School of Medicine, University of Miami, Miami, Florida.
    Background: Vasoconstrictors and local anesthetics are commonly administered using a squeeze bottle atomizer to the nasal mucosa to reduce edema, limit bleeding, and provide analgesia. Despite widespread use, there are few clinical guidelines that address technical details related to safe administration. The purpose of this study was to quantify, via simulation, the amount of liquid delivered to the nasal mucosa when patients are in the supine and upright positions and administration parameters that would reliably provide the desired amount of medication per spray. Read More

    Influence of Medical Insurance Under the Affordable Care Act on Access to Pain Management of the Trauma Patient.
    Reg Anesth Pain Med 2017 Jan/Feb;42(1):39-44
    From the Departments of *Orthopedics and Rehabilitation and †Adult and Perioperative Anesthesiology, Yale University School of Medicine, New Haven, CT.
    Background And Objectives: The Affordable Care Act intended to "extend affordable coverage" and "ensure access" for vulnerable patient populations. This investigation examined whether the type of insurance (Medicaid, Medicare, Blue Cross, cash pay) carried by trauma patients influences access to pain management specialty care.

    Methods: Investigators phoned 443 board-certified pain specialists, securing office visits with 235 pain physicians from 8 different states. Read More

    Management of neuroendocrine tumors.
    Am J Health Syst Pharm 2016 Nov;73(21):1729-1744
    Lyndon B. Johnson General Hospital, Harris Health System, Houston, TX.
    Purpose: Current strategies for managing neuroendocrine tumors (NETs) in adult patients are reviewed, with a focus on medication safety concerns.

    Summary: NETs usually originate in the gastrointestinal or bronchopulmonary tract. Symptoms due to hormonal hypersecretion often occur in patients with foregut or midgut NETs or liver metastases. Read More

    Inadvertent intrathecal injections and best practice management.
    Acta Anaesthesiol Scand 2017 Jan 21;61(1):11-22. Epub 2016 Oct 21.
    Department of Anesthesiology, LSUHSC-New Orleans, New Orleans, LA, USA.
    The intrathecal space has become an important anatomic site for medical intervention not only in anesthesia practice, but also in many other medical specialties. Undesired/inadvertent intrathecal injections (UII) are generally rare. There is tremendous variation in reported inadvertent administrations via an intrathecal route in the literature, mainly as individual cases and very small case-series reports. Read More

    32 years of experience with CO2 -LASER-assisted treatment for Zenker's Diverticulum - an update of 227 patients treated in Kiel.
    Clin Otolaryngol 2017 Jun 9;42(3):592-596. Epub 2016 Nov 9.
    Department of Otorhinolaryngology, Head and Neck Surgery, Christian-Albrechts-University of Kiel, Kiel, Germany.
    Objectives: To underline the value of the microendoscopic CO2 -LASER-assisted treatment (MEDCO2 ) for Zenker's diverticulum by investigating a large patient cohort treated in a single medical centre.

    Design: Retrospective cohort study of consecutive patients.

    Setting: Department of Otorhinolaryngology, Head and Neck Surgery, Christian-Albrechts-University Kiel, Germany. Read More

    The perioperative outcomes of eversion carotid endarterectomy in diabetic patients aged 80 years or older.
    J Vasc Surg 2016 Aug 22;64(2):348-353. Epub 2016 Mar 22.
    Department of Neurosciences, University of Padua, School of Medicine, Padova, Italy.
    Background: Uncertainty exists about the influence of advanced age and diabetes mellitus on the clinical effect of carotid endarterectomy (CEA). This study analyzed the perioperative (30-day) outcomes of CEA in diabetic patients aged ≥80 years.

    Methods: Data of 1872 consecutive patients who underwent 2125 primary eversion CEAs from 1990 to 2014 at our institution were prospectively stored in a vascular surgery registry. Read More

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