255 results match your criteria Perioperative DVT Prophylaxis


Risk factors of postoperative deep vein thrombosis (DVT) under low molecular weight heparin (LMWH) prophylaxis in patients with thoracolumbar fractures caused by high-energy injuries.

J Thromb Thrombolysis 2020 Jun 19. Epub 2020 Jun 19.

Department of Spinal Surgery, The Third Hospital of Hebei Medical University, 139 Ziqiang Street, Shijiazhuang, 050051, Hebei, China.

To determine the incidence of DVT and to evaluate the risk factors of DVT under LMWH prophylaxis in patients with thoracolumbar fractures caused by high‑energy injuries postoperatively. A total of 534 patients from January 2016 to November 2019 were included in this retrospective study. Medical record data, including demographic data, perioperative variables, and laboratory results, were collected. Read More

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http://dx.doi.org/10.1007/s11239-020-02192-7DOI Listing

Effect of Pharmacologic Prophylaxis on Venous Thromboembolism After Radical Prostatectomy: The PREVENTER Randomized Clinical Trial.

Eur Urol 2020 May 19. Epub 2020 May 19.

The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Background: Direct high-quality evidence is lacking evaluating perioperative pharmacologic prophylaxis (PP) after radical prostatectomy (RP) to prevent venous thromboembolism (VTE) leading to significant practice variation.

Objective: To study the impact of in-hospital PP on symptomatic VTE incidence and adverse events after RP at 30 d, with the secondary objective of evaluating overall VTE in a screening subcohort.

Design, Setting, And Participants: A prospective, phase 4, single-center, randomized trial of men with prostate cancer undergoing open or robotic-assisted laparoscopic RP was conducted (July 2017-November 2018). Read More

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http://dx.doi.org/10.1016/j.eururo.2020.05.001DOI Listing

Prophylaxis to prevent venous thromboembolism in patients undergoing vascular surgery procedures: A meta-analysis and systematic review.

J Vasc Surg Venous Lymphat Disord 2020 Apr 21. Epub 2020 Apr 21.

Division of Vascular Surgery, Penn State Heart and Vascular Institute, Pennsylvania State University College of Medicine, Hershey, Pa. Electronic address:

Objective: Perioperative venous thromboembolism (VTE) is generally considered preventable. Whereas the non-vascular surgery literature is rich in providing data about the impact of VTE prophylaxis on VTE outcomes, vascular surgery data are relatively sparse on this topic. This study sought to evaluate the evidence for VTE prophylaxis specifically for the population of vascular surgery patients. Read More

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http://dx.doi.org/10.1016/j.jvsv.2020.03.017DOI Listing

Incidence and Cost of Deep Vein Thrombosis in Emergency General Surgery Over 15 Years.

J Surg Res 2020 Aug 9;252:125-132. Epub 2020 Apr 9.

Department of Surgery, Rutgers New Jersey Medical School, Newark, New Jersey. Electronic address:

Background: Deep vein thromboses (DVTs) are a significant sequela of surgery and are associated with significant of morbidity and mortality in the United States. Operative emergency general surgery (EGS) cases have been demonstrated to have a greater burden of DVT than other types of surgery.

Materials And Methods: DVT in EGS cases were identified from the National Inpatient Sample-Healthcare Cost and Utilization Project database from 2001 to 2015 Q3 based on ICD-9 code specification. Read More

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http://dx.doi.org/10.1016/j.jss.2020.03.022DOI Listing

Postoperative Venous Thromboembolism in Extramedullary Spinal Tumors.

Asian J Neurosurg 2020 Jan-Mar;15(1):51-58. Epub 2020 Feb 25.

Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat-Yai, Songkhla, Thailand.

Context: Venous thromboembolism (VTE), including deep-vein thrombosis (DVT) and pulmonary embolism (PE), is the fatal complication following spine surgery and the appropriate perioperative prophylaxis is still debated.

Aims: The aim of this study is to evaluate the incidence of along with risk factors for postoperative VTE in surgically treated extramedullary spinal tumor patients.

Setting And Designs: The study design involves single institute and retrospective cohort study. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_279_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057870PMC
February 2020

The incidence of venous thromboembolism in children following colorectal resection for inflammatory bowel disease: A multi-center study.

J Pediatr Surg 2020 Feb 20. Epub 2020 Feb 20.

Division of Pediatric Surgery, Department of Surgery, Mayo Clinic, Rochester, MN, USA. Electronic address:

Background/purpose: Children with inflammatory bowel disease (IBD) have increased risk for venous thromboembolism (VTE). We sought to determine incidence and risk factors for postoperative VTE in a multicenter cohort of pediatric patients undergoing colorectal resection for IBD.

Methods: Retrospective review of children ≤18 years who underwent colorectal resection for IBD from 2010 to 2016 was performed at four children's hospitals. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2020.02.020DOI Listing
February 2020

Patient Safety Indicator-12 Rarely Identifies Problems with Quality of Care in Perioperative Venous Thromboembolism.

J Hosp Med 2019 Nov 20;14:E1-E6. Epub 2019 Nov 20.

Division of Hematology/Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.

Background: Patient safety indicators (PSI) were developed for hospitals to screen for healthcare-associated adverse events. PSIs are believed to be preventable and have become a part of major pay-for-performance programs. PSI-12 captures perioperative venous thromboembolism (VTE), which contributes to morbidity and mortality of hospitalized patients. Read More

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http://dx.doi.org/10.12788/jhm.3298DOI Listing
November 2019

Application of thromboelastography to evaluate the effect of different routes administration of tranexamic acid on coagulation function in total hip arthroplasty.

J Orthop Surg Res 2019 Dec 11;14(1):430. Epub 2019 Dec 11.

Department of Orthopaedic, The Fifth Affiliated Hospital Of Sun Yat-Sen University, No. 52, Meihua East Road, Zhuhai, 519000, Guangdong, China.

Background: Tranexamic acid (TXA) is widely used to reduce blood loss and transfusion rates in total hip arthroplasty(THA). Thromboelastography, which can monitor coagulation changes from clotting to fibrinolysis dynamically. In this study, thromboelastography was used to assess the dynamic changes in the coagulation of patients who underwent THA with the administration of TXA. Read More

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http://dx.doi.org/10.1186/s13018-019-1497-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6907225PMC
December 2019

One Versus Two Doses of Intravenous Tranexamic Acid in Total Knee Arthroplasty.

J Knee Surg 2019 Nov 15. Epub 2019 Nov 15.

Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.

Tranexamic acid (TXA) has been shown to reduce blood loss and postoperative transfusions in total knee arthroplasty (TKA). There is no consensus on the ideal dosing regimen in the literature, although there is a growing body of literature stating there is little benefit to additional doses. Our study compared one versus two doses of TXA in primary TKA and its effect on postoperative transfusion rate. Read More

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http://dx.doi.org/10.1055/s-0039-1700805DOI Listing
November 2019

Frequency and risk factors for venous thromboembolism after gastroenterological surgery based on the Japanese National Clinical Database (516 217 cases).

Ann Gastroenterol Surg 2019 Sep 22;3(5):534-543. Epub 2019 Jul 22.

Department of Gastroenterological Surgery Graduate School of Medicine Osaka University Suita Osaka Japan.

Aim: To investigate the frequency and risk factors of perioperative, symptomatic venous thromboembolism (VTE) after gastroenterological surgery.

Methods: We assessed the frequency of and risk factors for VTE after eight gastroenterological procedures (total 516 217 cases including, gastrectomy, total gastrectomy, hepatectomy, esophagectomy, right hemicolectomy, low anterior resection, pancreaticoduodenectomy, and acute pan-peritonitis surgery) based on data from the National Clinical Database. Data collected between 2011 and 2013 (382 124 cases) were used as a test set, and data from 2014 (134 093 cases) were used as a validation set. Read More

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http://dx.doi.org/10.1002/ags3.12275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6750140PMC
September 2019
2 Reads

The role of extended venous thromboembolism prophylaxis for major urological cancer operations.

BJU Int 2019 12 10;124(6):935-944. Epub 2019 Oct 10.

Department of Urology, Lister Hospital, Stevenage, UK.

Objectives: Venous thromboembolism (VTE), consisting of both pulmonary embolism (PE) and deep vein thromboses (DVT), remains a well-recognised complication of major urological cancer surgery. Several international guidelines recommend extended thromboprophylaxis (ETP) with LMWH, whereby the period of delivery is extended to the post-discharge period, where the majority of VTE occurs. In this literature review we investigate whether ETP should be indicated for all patients undergoing major urological cancer surgery, as well procedure specific data that may influence a clinician's decision. Read More

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http://dx.doi.org/10.1111/bju.14906DOI Listing
December 2019
5 Reads

The CU PAO: A Minimally Invasive, 2-Incision, Interlocking Periacetabular Osteotomy: Technique and Early Results.

J Bone Joint Surg Am 2019 Aug;101(16):1495-1504

Southern California Hip Institute, North Hollywood, California.

Background: The aims of this study were to describe a novel minimally invasive, interlocking periacetabular osteotomy (PAO) for the treatment of hip dysplasia that was developed at our institution and to report on its safety, complications, and early clinical outcomes.

Methods: This was a prospective longitudinal study of the first 200 consecutive hips that underwent the CU (University of Colorado) PAO, an interlocking osteotomy combining the benefits of the Birmingham interlocking pelvic osteotomy (BIPO) and the Ganz PAO. The technique provides direct visualization of the sciatic nerve during the ischial osteotomy and allows for immediate weight-bearing postoperatively. Read More

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http://dx.doi.org/10.2106/JBJS.19.00005DOI Listing
August 2019
2 Reads

Multi-route applications of tranexamic acid to reduce blood loss after total knee arthroplasty: a randomized controlled trial.

Medicine (Baltimore) 2019 Jul;98(30):e16570

Department of Orthopedics, Beijing Hospital ,National Center of Gerontology, PR China.

Background: Perioperative bleeding during total knee arthroplasty (TKA) is an ongoing problem for surgeons. Intravenous or topical application of tranexamic acid (TXA) can effectively stop bleeding, but there is still no uniform standard for the best method of administration and dose.

Methods: From October 2016 to September 2018, 218 patients with unilateral primary knee osteoarthritis requiring knee replacement were enrolled and randomly divided into four groups. Read More

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http://dx.doi.org/10.1097/MD.0000000000016570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709093PMC
July 2019
1 Read

Perioperative allogenic blood transfusion increases the incidence of postoperative deep vein thrombosis in total knee and hip arthroplasty.

J Orthop Surg Res 2019 Jul 23;14(1):235. Epub 2019 Jul 23.

State Key Laboratory of Pharmaceutical Biotechnology, Department of Sports Medicine and Adult Reconstructive Surgery, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, 321 Zhongshan Road, Nanjing, 210008, Jiangsu, People's Republic of China.

Background: Excessive blood loss caused by total joint arthroplasty (TJA) often increases the requirement for blood transfusion, which is associated with adverse outcomes. The purpose of this study was to determine the relationship between perioperative transfusion and postoperative DVT in TJA.

Methods: This retrospective study reviewed medical records of 715 patients, who consecutively underwent primary unilateral total knee arthroplasty (TKA) or total hip arthroplasty (THA) at our institution between September 2015 and March 2017. Read More

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http://dx.doi.org/10.1186/s13018-019-1270-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651957PMC
July 2019
1.577 Impact Factor

Investigation of the Incidence of Perioperative Pulmonary Embolism in Patients with Below-Knee Deep Vein Thrombosis after Lower Extremity Fracture and Evaluation of Retrievable Inferior Vena Cava Filter Deployment in These Patients.

Ann Vasc Surg 2019 Oct 8;60:45-51. Epub 2019 May 8.

Department of Vascular Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiaotong University, Shanghai, China. Electronic address:

Background: The objectives of the study were to investigate and compare the incidence of perioperative pulmonary embolism (PE) in trauma patients with below-knee deep vein thrombosis (BKDVT) and above-knee DVT (AKDVT) who need major orthopedic surgery and evaluate the usage of inferior vena cava (IVC) filters in these cases with BKDVT.

Methods: Between January 2003 and December 2017, patients with pelvic and/or lower extremity fracture diagnosed with DVT by duplex ultrasound were eligible for the study. A reduced-dose anticoagulation therapy was administered in patients without absolute contraindication to anticoagulation therapy during the perioperative period. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08905096193028
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http://dx.doi.org/10.1016/j.avsg.2019.02.027DOI Listing
October 2019
21 Reads
1.029 Impact Factor

Development and implementation of a comprehensive spine surgery enhanced recovery after surgery protocol: the Cleveland Clinic experience.

Neurosurg Focus 2019 04;46(4):E11

Departments of1Neurosurgery and.

Enhanced recovery after surgery (ERAS) protocols have been shown to be effective at reducing perioperative morbidity and costs while improving outcomes. To date, spine surgery protocols have been limited in scope, focusing only on specific types of procedures or specific parts of the surgical episode. The authors describe the creation and implementation of one of the first comprehensive ERAS protocols for spine surgery. Read More

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http://dx.doi.org/10.3171/2019.1.FOCUS18696DOI Listing
April 2019
27 Reads

Prophylactic Versus Therapeutic Mastectomy: A Contemporary Analysis of the ACS-NSQIP Database.

Clin Breast Cancer 2019 06 31;19(3):e428-e432. Epub 2019 Jan 31.

Division of Surgical Oncology, Department of Surgery, University of Massachusetts, Worcester, MA. Electronic address:

Introduction: The objective of the study was to evaluate the morbidity, mortality, and postoperative outcomes associated with simple or subcutaneous mastectomy in the management of prophylactic versus therapeutic resection. In this study we aimed to assess if simple or subcutaneous mastectomy for prophylaxis affects perioperative outcomes compared with resection performed for biopsy proven malignancy.

Materials And Methods: The American College of Surgeons National Surgical Quality Improvement Program database was queried for subjects who underwent simple or subcutaneous mastectomy between 2007 and 2012. Read More

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http://dx.doi.org/10.1016/j.clbc.2019.01.008DOI Listing
June 2019
4 Reads

Perioperative outcomes associated with thoracolumbar 3-column osteotomies for adult spinal deformity patients with rheumatoid arthritis

J Neurosurg Spine 2019 06 1;30(6):822-832. Epub 2019 Jun 1.

Departments of Neurological Surgery

Objective: Spinal deformity causing spinal imbalance is directly correlated to pain and disability. Prior studies suggest adult spinal deformity (ASD) patients with rheumatoid arthritis (RA) have more complex deformities and are at higher risk for complications. In this study the authors compared outcomes of ASD patients with RA following thoracolumbar 3-column osteotomies to outcomes of a matched control cohort. Read More

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June 2019
30 Reads

A Retrospective cohort study on the risk factors of deep vein thrombosis (DVT) for patients with traumatic fracture at Honghui Hospital.

BMJ Open 2019 03 3;9(3):e024247. Epub 2019 Mar 3.

Lab for Bone Metabolism, Key Lab for Space Biosciences and Biotechnology, School of Life Sciences, Northwestern Polytechnical University, Xi'an, China.

Objective: To explore the risk factors of perioperative deep vein thrombosis (DVT) in patients with traumatic fracture after orthopaedic surgery and their potential diagnostic values in clinical.

Design: Retrospective cohort study.

Setting: Clinical Laboratory of Honghui Hospital, Xi'an JiaoTong University College of Medicine, Xi'an, Shaanxi, China. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024247DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443064PMC
March 2019
18 Reads
2.063 Impact Factor

Postoperative thrombotic effects of tranexamic acid in open heart surgery.

Ir J Med Sci 2019 Nov 28;188(4):1373-1378. Epub 2019 Feb 28.

Department of Anesthesiology and Intensive Care, Health Sciences University Medical School, Istanbul, Turkey.

Background: Following the administration of tranexamic acid, the occurrence of thromboembolic events is a controversial issue.

Aims: In this retrospective cohort study, we aimed to determine the possible thromboembolic complications due to tranexamic acid as a prophylactic method in patients undergoing open heart surgery.

Methods: The data of 172 adult patients undergoing open heart surgery were analyzed. Read More

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http://link.springer.com/10.1007/s11845-019-01991-z
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http://dx.doi.org/10.1007/s11845-019-01991-zDOI Listing
November 2019
22 Reads

Extended thromboprophylaxis with low-molecular weight heparin (LMWH) following abdominopelvic cancer surgery.

Am J Surg 2019 09 16;218(3):537-550. Epub 2018 Dec 16.

Department of Surgery, Centre Hospitalier de l'Université de Montreal (CHUM), Surgical Division, Montreal University, 850 rue Saint-Denis, Montreal, Quebec, H2X 0A9, Canada. Electronic address:

Background: Venous thromboembolism (VTE) includes deep vein thrombosis (DVT) and pulmonary embolism (PE). Certain abdominopelvic cancer surgeries are associated with a six to 14-fold increased risk of DVT versus surgeries for benign disease, and extended thromboprophylaxis using perioperative LMWHs may further reduce VTE rates over standard duration administration. This review assesses the value of extended low molecular weight heparin (LMWH) thromboprophylaxis as a recommended strategy after abdominopelvic cancer surgery. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2018.11.046DOI Listing
September 2019
11 Reads

The efficacy and safety of tranexamic acid in reducing perioperative blood loss in patients with multilevel thoracic spinal stenosis: A retrospective observational study.

Medicine (Baltimore) 2018 Dec;97(50):e13643

Honghui Hospital, Xi'an Jiaotong University, No. 76 Nanguo Road, District Beilin, Xi'an, Shaanxi, China.

Study Design: A retrospective study.

Objective: To investigate the effectiveness and safety of intravenous tranexamic acid for reducing perioperative blood loss in patients with multilevel thoracic spinal stenosis (TSS).

Methods: This is a retrospective observational study of 42 patients with multilevel TSS admitted from December 2016 to October 2017 to the spine department of Honghui Hospital who underwent posterolateral bone graft fusion with posterior laminectomy and decompression fixation. Read More

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http://dx.doi.org/10.1097/MD.0000000000013643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320015PMC
December 2018
6 Reads

Thulium laser enucleation of the prostate (ThuLEP): Results, complications, and risk factors in 139 consecutive cases.

Arab J Urol 2018 Dec 5;16(4):411-416. Epub 2018 Jul 5.

Department of Urology and Men's Health, Al Garhoud Private Hospital, Dubai, United Arab Emirates.

Objectives: To report our experience with the emerging technique of thulium laser enucleation of the prostate (ThuLEP) for the treatment for prostate hyperplasia.

Patients And Methods: Our inclusion criteria were an International Prostate Symptom Score (IPSS) of >15 and a quality-of-life (QoL) score of >3 in patients with confirmed bladder outflow obstruction, no longer responsive to medical therapy, with a significant post-void residual urine volume (PVR; >100 mL), with or without recurrent urinary tract infection and/or acute urinary retention. Patients with neurogenic bladder, urethral strictures, bladder stones, and previously failed transurethral prostate surgery were excluded. Read More

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http://dx.doi.org/10.1016/j.aju.2018.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277267PMC
December 2018
30 Reads

Low-molecular-weight heparin followed by rivaroxaban or not for the prevention of deep venous thromboembolism after total knee arthroplasty.

Blood Coagul Fibrinolysis 2019 Jan;30(1):29-33

Department of Orthopedics, The Second Xiangya Hospital.

: To observe the effect of LMWH followed by rivaroxaban for the prevention of DVT after TKA. Between June 2015 and November 2017 as well as in accordance with the inclusion criteria, 118 patients undergoing TKA were randomly allocated to two groups. Patients in group A were applied LMWH, whereas patients in group B received LMWH followed by rivaroxaban postoperatively. Read More

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http://Insights.ovid.com/crossref?an=00001721-900000000-9859
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http://dx.doi.org/10.1097/MBC.0000000000000786DOI Listing
January 2019
38 Reads
1.380 Impact Factor

Keep It Moving and Remember to P.A.C. (Pharmacology, Ambulation, and Compression) for Venous Thromboembolism Prevention.

Orthop Nurs 2018 Nov/Dec;37(6):339-345

Kathleen Wilson, MSN, RN, CNL, SCRN, Clinical Nurse Educator Ortho and Neuro, Robert Wood Johnson University Hospital Somerset, Somerville, NJ. Dawnmarie Devito, BSN, RN, CPAN, Clinical Nurse Educator Perioperative Services, Robert Wood Johnson University Hospital New Brunswick, New Brunswick, NJ. Kathleen Evanovich Zavotsky, PhD, RN, CCRN, CEN, ACNS-BC, FAEN, Assistant Vice President, The Center for Professional Development, Innovation and Research, Robert Wood Johnson University Hospital New Brunswick, New Brunswick, NJ. Mitch Rusay, RPh, Performance Improvement Coordinator, Performance Improvement, Robert Wood Johnson University Hospital New Brunswick, New Brunswick, NJ. Megan Allen, MSN, RN, CCM, CCDS, Performance Improvement Coordinator, Performance Improvement, Robert Wood Johnson University Hospital Somerset, Somerville, NJ. Stephanie Huang, BS, RN, CCRN, Staff Nurse, Cardiothoracic Surgical ICU, Robert Wood Johnson University Hospital New Brunswick, New Brunswick, NJ.

The purpose of this article is to describe in detail how an academic hospital system took on the challenge of deep vein thrombosis (DVT) prevention. A VTE Prevention Task Force was formed in response to an increased incidence of hospital acquired DVTs. The interdisciplinary team reviewed the literature and examined the current state of organizational venous thromboembolism (VTE) prevention to identify gaps in process, determine opportunity and approaches for practice and process improvements, and develop standardized VTE prevention protocols. Read More

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http://dx.doi.org/10.1097/NOR.0000000000000497DOI Listing
December 2018
53 Reads

Rapidly progressive cervical myelopathy had a high risk of developing deep venous thrombosis: a prospective observational study in 289 cases with degenerative cervical spine disease.

Spinal Cord 2019 Jan 29;57(1):58-64. Epub 2018 Oct 29.

Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.

Study Design: A prospective observational study.

Objectives: To determine the incidence of deep venous thrombosis (DVT) and to evaluate the risk factors for DVT development associated with degenerative cervical spine disease.

Setting: Hokkaido Spinal Cord Injury Center, Japan. Read More

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http://www.nature.com/articles/s41393-018-0213-9
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http://dx.doi.org/10.1038/s41393-018-0213-9DOI Listing
January 2019
61 Reads

Prevalence of venous thromboembolism after lung surgery in China: a single-centre, prospective cohort study involving patients undergoing lung resections without perioperative venous thromboembolism prophylaxis†.

Eur J Cardiothorac Surg 2019 Mar;55(3):455-460

Department of Thoracic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.

Objectives: Venous thromboembolism (VTE) is a common postoperative complication. Previous studies have shown that the incidence of VTE after major thoracic surgery ranges from 2.3% to 15%. Read More

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http://dx.doi.org/10.1093/ejcts/ezy323DOI Listing
March 2019
48 Reads

Severe Leg Pain Following Spinal Cord Stimulator Implantation - A Case Report.

PM R 2019 03 13;11(3):317-321. Epub 2019 Feb 13.

Department of Physical Medicine and Rehabilitation, Penn State Hershey Medicine Center, Penn State College of Medicine, Hummelstown, PA.

Following spinal cord stimulator (SCS) implantation, postoperative pain is commonly incisional or neuropathic from neurological damage. Occasionally, this new pain may mimic symptoms caused by preexisting pathology. This article presents a case of immediate, severe, postoperative leg pain secondary to a lower extremity deep vein thrombosis (DVT) and subsequent pulmonary embolism after percutaneous SCS implantation for failed back syndrome. Read More

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http://dx.doi.org/10.1016/j.pmrj.2018.09.024DOI Listing
March 2019
14 Reads

Prospective implementation of a standardized screening protocol for deep venous thrombosis in abdominal surgical oncology patients.

J Surg Oncol 2018 Sep 16;118(3):568-573. Epub 2018 Aug 16.

Division of Endocrine and Oncologic Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

Background And Objectives: Venous thromboembolism (VTE) remains a major cause of perioperative morbidity and mortality despite implementation of prophylaxis guidelines. We sought to identify risk factors for occult deep venous thrombosis (DVT) following abdominal surgery for cancer and measure the clinical impact of a prospectively implemented standardized postoperative DVT screening protocol.

Methods: Patients undergoing abdominal surgery for malignant indication were screened with early postoperative lower extremity duplex to identify DVT. Read More

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http://dx.doi.org/10.1002/jso.25151DOI Listing
September 2018
10 Reads

OBTAIN E: outcome benefits of tranexamic acid in hip arthroplasty with enoxaparin: a randomised double-blinded controlled trial.

Hip Int 2019 May 24;29(3):239-244. Epub 2018 Jul 24.

1 Department of Orthopaedic Surgery, Western Health, Melbourne, Australia.

Background: We examined the blood conserving effect of tranexamic acid in total hip arthroplasty using the direct anterior approach with enoxaparin as deep vein thrombosis (DVT) chemoprophylaxis, and whether this translates to an effect on functional outcomes in the perioperative period. We also compare the effect of aspirin and enoxaparin as DVT chemoprophylactic agents.

Methods: We conducted a single-centre randomised, double-blinded, placebo-controlled trial. Read More

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http://dx.doi.org/10.1177/1120700018780125DOI Listing
May 2019
3 Reads

Anticoagulation for perioperative thromboprophylaxis in people with cancer.

Cochrane Database Syst Rev 2018 07 11;7:CD009447. Epub 2018 Jul 11.

Department of Internal Medicine, American University of Beirut Medical Center, Riad El Solh, Beirut, Lebanon, 1107 2020.

Background: The choice of the appropriate perioperative thromboprophylaxis for people with cancer depends on the relative benefits and harms of different anticoagulants.

Objectives: To systematically review the evidence for the relative efficacy and safety of anticoagulants for perioperative thromboprophylaxis in people with cancer.

Search Methods: This update of the systematic review was based on the findings of a comprehensive literature search conducted on 14 June 2018 that included a major electronic search of Cochrane Central Register of Controlled Trials (CENTRAL, 2018, Issue 6), MEDLINE (Ovid), and Embase (Ovid); handsearching of conference proceedings; checking of references of included studies; searching for ongoing studies; and using the 'related citation' feature in PubMed. Read More

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http://dx.doi.org/10.1002/14651858.CD009447.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389341PMC
July 2018
55 Reads

Efficacy and safety of low-molecular-weight heparin after knee arthroscopy: A meta-analysis.

PLoS One 2018 21;13(6):e0197868. Epub 2018 Jun 21.

Department of Orthopaedics, Guizhou Provincial People's Hospital, Guiyang, Guizhou, China.

Background: Venous thromboembolism (VTE) is considered a potentially serious complication of knee arthroscopy and leads to conditions such as deep venous thrombosis (DVT) and pulmonary embolism (PE). Low-molecular-weight heparin (LMWH) is widely employed in knee arthroscopy to reduce perioperative thromboembolic complications. However, the efficacy and safety of LMWH in knee arthroscopy remains unclear. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197868PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013230PMC
December 2018
39 Reads

Semiautomatic intermittent pneumatic compression device applied to deep vein thrombosis in major orthopedic surgery.

Biomed Eng Online 2018 Jun 15;17(1):78. Epub 2018 Jun 15.

Department of Orthopedic Surgery, Shengjing Hospital of China Medical University, Shenyang, 11000, Liaoning, China.

Objective: To investigate the effect of additional semiautomatic intermittent pneumatic compression device (IPCD) in the prevention of deep vein thrombosis (DVT) of lower extremity in these patients undergoing major orthopedic surgery, when compared with the conventional graduated compression stockings alone.

Methods: The data of 112 patients undergoing major orthopedic surgery were retrospectively analyzed. 51 patients who ever received IPCD and graduated compression stockings during major orthopedic surgery were taken as the experimental group, and 61 patients who only received the conventional graduated compression stockings during surgery were taken as the observation group. Read More

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http://dx.doi.org/10.1186/s12938-018-0513-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002995PMC
June 2018
58 Reads

Association of Perioperative Red Blood Cell Transfusions With Venous Thromboembolism in a North American Registry.

JAMA Surg 2018 09;153(9):826-833

Division of Transfusion Medicine, Department of Pathology, Johns Hopkins University, Baltimore, Maryland.

Importance: Increasing evidence supports the role of red blood cells (RBCs) in physiological hemostasis and pathologic thrombosis. Red blood cells are commonly transfused in the perioperative period; however, their association with postoperative thrombotic events remains unclear.

Objective: To examine the association between perioperative RBC transfusions and postoperative venous thromboembolism (VTE) within 30 days of surgery. Read More

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http://archsurg.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamasurg.2018.1565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233649PMC
September 2018
58 Reads

Impact of anesthesia modality and mechanical venous thromboembolism prophylaxis on the incidence of symptomatic deep venous thrombosis after TKA.

J Clin Orthop Trauma 2018 Apr-Jun;9(2):142-145. Epub 2016 Nov 18.

Division of Information Science and Biostatistics, Niigata University Graduate School of Medical and Dental Sciences, 1 Asahimachi Dori Niigata, Niigata 951-8520, Japan.

Background: Venous thromboembolic events (VTE) are a common complication of total knee arthroplasty (TKA). Prior studies have discussed the utility of mechanical VTE prophylaxis as a monotherapy for low-risk TKA patients. We assess the incidence of clinically significant deep venous thrombosis (DVT) or pulmonary embolism (PE) in low-risk TKA patients who receive mechanical VTE prophylaxis and undergo spinal, epidural, or general anesthesia for their surgery. Read More

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http://dx.doi.org/10.1016/j.jcot.2016.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995002PMC
November 2016
32 Reads

Effects of Natural Hirudin and Low Molecular Weight Heparin in Preventing Deep Venous Thrombosis in Aged Patients with Intertrochanteric Fracture.

Sci Rep 2018 06 11;8(1):8847. Epub 2018 Jun 11.

Department of Othopedics, West China Hospital, Sichuan University, 37# Wainan Guoxue Road, Chendu, 610041, People's Republic of China.

Our objective was to evaluate the efficacy and safety of natural hirudin and low molecular weight heparin (LMWH) in the prevention of perioperative deep venous thrombosis (DVT) in elderly patients with intertrochanteric fracture. From June 2014 to June 2017, 96 patients with intertrochanteric fractures were treated with proximal femoral nail antirotation (PFNA) were randomly divided into two groups. For DVT prevention, 45 patients were treated with oral natural hirudin and subcutaneous LMWH-calcium (test group) and 51 patients were treated with subcutaneous LMWH-calcium (control group). Read More

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http://dx.doi.org/10.1038/s41598-018-27243-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995864PMC
June 2018
30 Reads
5.080 Impact Factor

Validating the role of ABO blood type in risk of perioperative venous thromboembolism after radical cystectomy.

World J Urol 2019 Jan 6;37(1):173-179. Epub 2018 Jun 6.

Norris Comprehensive Cancer Center, USC Institute of Urology, Los Angeles, CA, USA.

Purpose: To validate the relationship between ABO blood type and risk of VTE post-RC in a large retrospective database.

Methods: Patients with urothelial bladder cancer (UBC) who underwent RC (intent-to-cure) for whom ABO blood type was available between 2003 and 2015 were identified from our IRB-approved database. VTE was defined as deep vein thrombosis (DVT) or pulmonary embolism (PE) within 90 days of surgery. Read More

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http://dx.doi.org/10.1007/s00345-018-2351-2DOI Listing
January 2019
48 Reads

The significance of perioperative coagulation and fibrinolysis related parameters after lung surgery for predicting venous thromboembolism: a prospective, single center study.

J Thorac Dis 2018 Apr;10(4):2223-2230

Department of Thoracic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China.

Background: The high incidence of venous thromboembolism (VTE) has been perceived in post thoracic surgery patients. However, the significance of perioperative coagulation and fibrinolysis related parameters after lung surgery for VTE predicting is not clear. To investigate that, we conducted a prospective single center study. Read More

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http://dx.doi.org/10.21037/jtd.2018.03.174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949486PMC
April 2018
23 Reads

European perspectives in Thoracic Surgery, the ESTS venous thromboembolism (VTE) working group.

J Thorac Dis 2018 Apr;10(Suppl 8):S963-S968

Division of Thoracic Surgery, Department of Surgery, Boston University, Boston, MA, USA.

Venous thromboembolism (VTE), composed of deep vein thrombosis (DVT) and PE is a well-recognized cause for significant perioperative morbidity and mortality. While in orthopedic surgery and general oncology surgery there are well established guidelines regarding VTE prophylaxis, based on carefully conducted high level studies, in thoracic surgery the level of evidence and overall knowledge in the field is still lacking, The European Society of Thoracic Surgeons have established an international working group in 2016, whose task was the define contemporary best practice, coordinate research efforts and eventually define best practice guidelines. This collaboration has matured into a multi-organizational effort, with participation of the American Association for Thoracic Surgery, the International Society on Thrombosis and Haemostasis and Chinese and Japanese thoracic societies. Read More

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http://dx.doi.org/10.21037/jtd.2018.04.70DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934119PMC
April 2018
16 Reads

Systematic review and meta-analyses of tranexamic acid use for bleeding reduction in prostate surgery.

J Clin Anesth 2018 08 1;48:32-38. Epub 2018 May 1.

Department of Surgery, University Hospital, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil.

Background: Prostate cancer and benign prostatic hyperplasia have an increased incidence with aging. The most effective treatments are radical prostatectomy and transurethral resection of the prostate. To reduce perioperative bleeding in these surgeries, an approach is the use of tranexamic acid (TXA). Read More

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http://dx.doi.org/10.1016/j.jclinane.2018.04.014DOI Listing
August 2018
4 Reads

Additional Dose of Intravenous Tranexamic Acid after Primary Total Knee Arthroplasty Further Reduces Hidden Blood Loss.

Chin Med J (Engl) 2018 Mar;131(6):638-642

Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing 100191, China.

Background: Total knee arthroplasty (TKA) is the most frequently performed procedure in treating advanced knee osteoarthritis. Excessive perioperative blood loss can sometimes lead to postoperative anemia. Tranexamic acid (TXA) is a potent fibrinolysis inhibitor which has been extensively used at the surgical incision and closure to lower overall blood loss in adult reconstruction surgery. Read More

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http://dx.doi.org/10.4103/0366-6999.226884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865307PMC
March 2018
8 Reads

Inferior Vena Cava Filters: Current Indications, Techniques, and Recommendations.

Surg Clin North Am 2018 Apr;98(2):293-319

Division of Vascular and Endovascular Surgery, University of Texas Southwestern Medical Center, Professional Office Building 1, Suite 620, 5959 Harry Hines Boulevard, Dallas, TX 75390-9157, USA. Electronic address:

The vena cava filter (VCF) is intended to prevent the progression of deep venous thrombosis to pulmonary embolism. Recently, the indications for VCF placement have expanded, likely due in part to newer retrievable inferior vena caval filters and minimally invasive techniques. This article reviews the available VCFs, the indications for use, the techniques for placement, and possible outcomes and complications. Read More

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http://dx.doi.org/10.1016/j.suc.2017.11.011DOI Listing
April 2018
20 Reads

The role of preoperative deep vein thrombosis screening in neurooncology.

J Neurosurg 2018 03;130(1):38-43

Departments of1Neurosurgery and.

OBJECTIVEVenous thromboembolism (VTE) is a major cause of morbidity in patients undergoing neurosurgical intervention. The authors postulate that the introduction of a routine preoperative deep vein thrombosis (DVT) screening protocol for patients undergoing neurosurgical intervention for brain tumors would result in a more effective diagnosis of DVT in this high-risk subgroup, and subsequent appropriate management of the condition would reduce pulmonary embolism (PE) rates and improve patient outcomes.METHODSThe authors conducted a prospective study of 115 adult patients who were undergoing surgical intervention for a brain tumor. Read More

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http://dx.doi.org/10.3171/2017.9.JNS17176DOI Listing
March 2018
36 Reads

Antithrombotic Therapy for Venous Thromboembolism and Prevention of Thrombosis in Otolaryngology-Head and Neck Surgery: State of the Art Review.

Otolaryngol Head Neck Surg 2018 04 27;158(4):627-636. Epub 2018 Feb 27.

2 Department of Otolaryngology-Head and Neck Surgery, School of Medicine, University of Michigan, Ann Arbor, Michigan, USA.

Objective The aim of this report is to present a cohesive evidence-based approach to reducing venous thromboembolism (VTE) in otolaryngology-head and neck surgery. VTE prevention includes deep venous thrombosis and pulmonary embolism. Despite national efforts in VTE prevention, guidelines do not exist for otolaryngology-head and neck surgery in the United States. Read More

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http://dx.doi.org/10.1177/0194599818756599DOI Listing
April 2018
10 Reads

Deep Vein Thrombosis After Complex Posterior Spine Surgery: Does Staged Surgery Make a Difference?

Spine Deform 2018 Mar - Apr;6(2):141-147. Epub 2017 Oct 20.

The Maryland Spine Center, Mercy Medical Center, 301 St Paul Pl, Baltimore, MD 21202, USA.

Study Design: Retrospective review of a prospectively collected database.

Objective: To assess the incidence of deep vein thrombosis (DVT) associated with single- versus multistage posterior-only complex spinal surgeries.

Summary Of Background Data: Dividing the physiologic burden of spinal deformity surgery into multiple stages has been suggested as a potential means of reducing perioperative complications. Read More

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http://dx.doi.org/10.1016/j.jspd.2017.08.012DOI Listing
December 2018
28 Reads

Proximal Femoral Fractures and Anticoagulation Therapy - When Is Surgery Safe?

Acta Chir Orthop Traumatol Cech 2017 ;84(5):323-329

Klinik für Unfallchirurgie, Orthopädie und Handchirurgie, Klinikum Wolfsburg, Wolfsburg, Germany.

Patients presenting with proximal femur fractures are at high risk of developing DVT and pulmonary embolism. Many of these patients suffer from additional anticoagulant treatment. Patients on anticoagulation treatment are complex to manage, especially regarding timing of surgery due to implemented quality control recommendations. Read More

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August 2018
6 Reads

The comparative efficacy and safety of topical and intravenous tranexamic acid for reducing perioperative blood loss in Total knee arthroplasty- A randomized controlled non-inferiority trial.

Knee 2018 Jan 17;25(1):185-191. Epub 2018 Jan 17.

Sunshine Hospitals, Secunderabad, Telangana 500003, India.

Background: Total Knee Arthroplasty (TKA) can be associated with significant perioperative blood loss and blood transfusions. This is a prospective randomised non-inferiority trial comparing intraarticular (IA) and intravenous (IV) routes of administering Tranexamic acid (TXA) with regard to efficacy and safety.

Methods: A total of 113 patients who underwent primary unilateral TKA from January to June 2017 randomly received either 1. Read More

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http://dx.doi.org/10.1016/j.knee.2017.11.006DOI Listing
January 2018
16 Reads

A Systematic Review and Meta-analysis of the Topical Administration of Fibrin Sealant in Total Hip Arthroplasty.

Sci Rep 2018 01 8;8(1):78. Epub 2018 Jan 8.

Orthopaedics Institute, Tianjin Hospital, Tianjin, 300050, People's Republic of China.

Patients who undergo total hip arthroplasty (THA) may experience a large amount of blood loss. The objective of our study is to include randomized controlled trials (RCTs) and compare the clinical outcomes of fibrin sealant (FS) versus placebo after a THA. In October 2015, we searched the following databases: Medline, Embase, PubMed, the Cochrane Controlled Trials Register, Web of Science, the China National Knowledge Infrastructure, the China Wanfang database and Google Scholar. Read More

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http://www.nature.com/articles/s41598-017-16779-3
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http://dx.doi.org/10.1038/s41598-017-16779-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758515PMC
January 2018
16 Reads

Risk and incidence of perioperative deep vein thrombosis in patients undergoing gastric cancer surgery.

Surg Today 2018 May 12;48(5):525-533. Epub 2017 Dec 12.

Division of Surgical Oncology, Department of Surgery, School of Medicine, Tottori University Faculty of Medicine, 36-1 Nishi-cho, Yonago, 683-8504, Japan.

Background And Purpose: Venous thromboembolism (VTE) is a potentially fatal perioperative complication. Understanding the risk factors for deep vein thrombosis (DVT) and initiating appropriate prophylaxis is pivotal for reducing the risk of VTE. The purpose of this study was to clarify the perioperative risk factors for DVT in patients undergoing surgery for gastric cancer. Read More

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http://dx.doi.org/10.1007/s00595-017-1617-4DOI Listing
May 2018
27 Reads

The extent of vascular resection is associated with perioperative outcome in patients undergoing pancreaticoduodenectomy.

HPB (Oxford) 2018 02 27;20(2):140-146. Epub 2017 Nov 27.

Pritzker School of Medicine, University of Chicago, Chicago, IL, USA; Department of Surgery, NorthShore University HealthSystem, Evanston, IL, USA. Electronic address:

Background: Few studies have examined the relation between extent of vascular resection and morbidity following pancreaticoduodenectomy (PD) with vein resection (PDVR).

Methods: Patients undergoing PD for malignancy were identified using the American College of Surgeons National Surgical Quality Improvement Project from 2006 to 2013. Current procedural terminology codes were used to characterize PDVR. Read More

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http://dx.doi.org/10.1016/j.hpb.2017.08.012DOI Listing
February 2018
62 Reads