728 results match your criteria Perioperative Anticoagulation Management


Enhanced Recovery Pathways for Cardiac Surgery.

Curr Pain Headache Rep 2019 Mar 14;23(4):28. Epub 2019 Mar 14.

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Purpose Of Review: Enhanced recovery after surgery (ERAS) has become a widespread topic in perioperative medicine over the past 20 years. The goals of ERAS are to improve patient outcomes and perioperative experience, reduce length of hospital stay, minimize complications, and reduce cost. Interventions and factors before, during, and after surgery all potentially play a role with the cumulative effect being superior quality of patient care. Read More

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http://link.springer.com/10.1007/s11916-019-0764-2
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http://dx.doi.org/10.1007/s11916-019-0764-2DOI Listing
March 2019
2 Reads

Perioperative Considerations in the Management of Anticoagulation Therapy for Patients Undergoing Surgery.

Curr Pain Headache Rep 2019 Feb 22;23(2):13. Epub 2019 Feb 22.

Department of Anesthesiology, Yale University School of Medicine, TMP3 333, Cedar Street, New Haven, CT, USA.

Purpose Of Review: As ambulatory surgery has become increasingly more common, the appropriate management of anticoagulation therapy in patients undergoing invasive procedures has become progressively more relevant to healthcare professionals. The purpose of this literature review is to provide an overview of current common anaticoagulants and their pharmacological properties and to evaluate recent relevant literature and bridging therapy and provide recommendations on risk-guided therapy.

Recent Findings: With the development of new drugs and the advancing study and practice of anticoagulation use, clinicians must keep up-to-date on the optimal management of patients requiring anticoagulation. Read More

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http://link.springer.com/10.1007/s11916-019-0747-3
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http://dx.doi.org/10.1007/s11916-019-0747-3DOI Listing
February 2019
4 Reads

Management of Patients Taking Oral Anticoagulants Who Need Urgent Surgery for Hip Fracture.

Semin Thromb Hemost 2019 Mar 11;45(2):164-170. Epub 2019 Feb 11.

Dipartimento di Scienze Mediche Internistiche, University of Cagliari, Cagliari, Italy.

The number of hip fractures in anticoagulated patients is predicted to increase, due to people living longer. However, evidence regarding urgent perioperative management of elderly patients with hip fracture who take oral anticoagulants (vitamin K antagonists or direct oral anticoagulants) is scarce. In this article, the authors present a narrative review of the evidence to date supporting the urgent management of hip fracture in anticoagulated elderly patients. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1678718
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http://dx.doi.org/10.1055/s-0039-1678718DOI Listing
March 2019
3 Reads

Impact of drugs on venous thromboembolism risk in surgical patients.

Eur J Clin Pharmacol 2019 Feb 5. Epub 2019 Feb 5.

Faculty of Medicine, University of Ljubljana, Vrazov trg 2, SI-1104, Ljubljana, Slovenia.

Purpose: This review focuses on the most common drugs administered to surgical patients during the perioperative period that affect the risk of venous thromboembolism (VTE).

Results: Among analgesics, the risk of VTE is increased in patients treated with diclofenac, ibuprofen, and rofecoxib, but not naproxen, while metamizole can confer a protective effect. The relationship between sedatives and VTE has not been sufficiently studied. Read More

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http://link.springer.com/10.1007/s00228-019-02636-x
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http://dx.doi.org/10.1007/s00228-019-02636-xDOI Listing
February 2019
4 Reads

Venous Thromboembolism After Degenerative Spine Surgery: A Nationwide Readmissions Database Analysis.

World Neurosurg 2019 Jan 23. Epub 2019 Jan 23.

Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

Background: Venous thromboembolism (VTE) is an appreciable burden on health care. The protracted recumbency experienced by many spinal patients juxtaposed with concerns for postoperative hemorrhage from early anticoagulation results in conflicting stances regarding chemoprophylaxis. Identifying risk factors associated with VTE is therefore instrumental in guiding management. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.029DOI Listing
January 2019
3 Reads

Perioperative bridging of vitamin K antagonist treatment in patients with atrial fibrillation: only a very small group of patients benefits.

Europace 2019 Jan 12. Epub 2019 Jan 12.

Department of Health Sciences, University of Groningen, University Medical Center, Groningen, The Netherlands.

Aims: Bridging anticoagulation in atrial fibrillation (AF) patients who need to interrupt vitamin K antagonists for procedures is a clinical dilemma. Currently, guidelines recommend clinicians to take the stroke and bleeding risk into consideration, but no clear thresholds are advised. To aid clinical decision making, we aimed to develop a model in which periprocedural bridging therapy is compared with withholding anticoagulation in AF patients, for several bleeding and stroke risk groups. Read More

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http://dx.doi.org/10.1093/europace/euy308DOI Listing
January 2019
4 Reads

The prevention of infection: 12 modifiable risk factors.

Bone Joint J 2019 01;101-B(1_Supple_A):3-9

Department of Orthopaedic Surgery, Carolinas Medical Center, Charlotte, North Carolina, USA and OrthoCarolina Hip and Knee Center, Charlotte, North Carolina, USA.

Aims: Prosthetic joint infection (PJI) remains a serious complication that is associated with high morbidity and costs. The aim of this study was to prepare a systematic review to examine patient-related and perioperative risk factors that can be modified in an attempt to reduce the rate of PJI.

Materials And Methods: A search of PubMed and MEDLINE was conducted for articles published between January 1990 and February 2018 with a combination of search terms to identify studies that dealt with modifiable risk factors for reducing the rate of PJI. Read More

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https://online.boneandjoint.org.uk/doi/10.1302/0301-620X.101
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http://dx.doi.org/10.1302/0301-620X.101B1.BJJ-2018-0233.R1DOI Listing
January 2019
5 Reads

[Evidence-based perioperative medicine].

Chirurg 2019 Jan 9. Epub 2019 Jan 9.

Klinik für Allgemein‑, Viszeral- und Transplantationschirurgie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 110, 69120, Heidelberg, Deutschland.

Perioperative medical interventions are an integral part of modern surgical management. In addition to the main manual aspects of surgical interventions, surgeons must also be familiar with preoperative and postoperative medical interventions. This ranges from the indications for perioperative anticoagulation, handling of drainage, adjusting the perioperative analgesia, prescribing an antibiotic prophylaxis to deciding whether a preoperative bowel preparation is necessary. Read More

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http://dx.doi.org/10.1007/s00104-018-0776-1DOI Listing
January 2019
3 Reads

Medical therapy for atherosclerotic cardiovascular disease in patients with myocardial injury after non-cardiac surgery.

Int J Cardiol 2019 Mar 12;279:1-5. Epub 2018 Dec 12.

Department of Anesthesiology, Perioperative Care, and Pain Medicine, New York University Langone Medical Center, New York, NY, United States of America.

Background: Myocardial injury after non-cardiac surgery (MINS) is a common post-operative cardiovascular complication and is associated with short and long-term mortality. The objective of this study was to describe the contemporary management of patients with and without MINS after total joint and spine orthopedic surgery at a large urban health system in the United States.

Methods: Adults admitted for total joint and major spine surgery from January 2013 through December 2015 with ≥1 cardiac troponin (cTn) measurement during their hospitalization were identified. Read More

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http://dx.doi.org/10.1016/j.ijcard.2018.12.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358460PMC
March 2019
2 Reads

Extended thromboprophylaxis with low-molecular weight heparin (LMWH) following abdominopelvic cancer surgery.

Am J Surg 2018 Dec 16. Epub 2018 Dec 16.

Department of Surgery, Centre Hospitalier de l'Université de Montreal (CHUM), Surgical Division, Montreal University, 850 rue Saint-Denis, Montreal, Quebec, H2X 0A9, Canada. Electronic address:

Background: Venous thromboembolism (VTE) includes deep vein thrombosis (DVT) and pulmonary embolism (PE). Certain abdominopelvic cancer surgeries are associated with a six to 14-fold increased risk of DVT versus surgeries for benign disease, and extended thromboprophylaxis using perioperative LMWHs may further reduce VTE rates over standard duration administration. This review assesses the value of extended low molecular weight heparin (LMWH) thromboprophylaxis as a recommended strategy after abdominopelvic cancer surgery. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2018.11.046DOI Listing
December 2018
3 Reads

Stopping or maintaining oral anticoagulation in patients undergoing photoselective vaporization of the prostate (SOAP) surgery for benign prostate obstruction: study protocol for a multicentre randomized controlled trial.

Trials 2018 Dec 27;19(1):705. Epub 2018 Dec 27.

Department of Urology, Clinique Pasteur, 45 avenue de Lombez, BP 27 617, 31076, Toulouse Cedex 3, France.

Background: Lower urinary tract symptoms related to benign prostatic obstruction (BPO) are frequent in men aged > 50 years. Based on the use of innovative medical devices, a number of transurethral ablative techniques have recently been developed for the surgical treatment of BPO. In recent years, GreenLight photoselective vaporization of the prostate (PVP) has been considered as a non-inferior alternative to transurethral resection of the prostate. Read More

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http://dx.doi.org/10.1186/s13063-018-3066-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307178PMC
December 2018
1 Read

Canadian Urological Association guideline on perioperative thromboprophylaxis and management of anticoagulation.

Can Urol Assoc J 2018 Dec 14. Epub 2018 Dec 14.

Department of Surgery, Division of Urology, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.5828DOI Listing
December 2018
5 Reads

Best practice in the management of benign prostatic hyperplasia in the patients requiring anticoagulation.

Ther Adv Urol 2018 Dec 29;10(12):431-436. Epub 2018 Oct 29.

Indiana University School of Medicine, IU Health Physicians Urology, 1801 N. Senate Blvd., Indianapolis, IN 46202-5114, USA.

In today's aging population, urologists are often treating older patients with multiple comorbidities. Lower urinary tract symptoms from benign prostate hyperplasia (LUTS/BPH) is a common condition that affects men, with increasing prevalence as men age. In a subset of patients, the symptoms are too severe or refractory to medical therapy and, therefore, surgical therapy is required to improve their LUTS. Read More

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http://dx.doi.org/10.1177/1756287218807591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295789PMC
December 2018
2 Reads

Periprocedural Antithrombotic Management from a Patient Perspective: A Qualitative Analysis.

Am J Med 2018 Dec 3. Epub 2018 Dec 3.

Center for Bioethics and Social Science in Medicine; Frankel Cardiovascular Center. Electronic address:

Background: Periprocedural antithrombotic medication management is a complex, often confusing process for patients and their providers. Communication difficulties often lead to suboptimal medication management, resulting in delayed or canceled procedures.

Methods: We conducted telephone surveys with patients taking chronic antithrombotic medications who had recently undergone an endoscopy procedure. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029343183114
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http://dx.doi.org/10.1016/j.amjmed.2018.11.020DOI Listing
December 2018
26 Reads

Insight into the perioperative management of direct oral anticoagulants: concerns and considerations.

Expert Opin Pharmacother 2019 03 6;20(4):465-472. Epub 2018 Dec 6.

d Division of Cardiology, Department of Medicine and Therapeutics , The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong , China.

Introduction: Direct oral anticoagulants (DOACs) have gained momentum in recent years in patients requiring anticoagulation for the prevention and management of venous thromboembolism and thromboembolic events caused by atrial fibrillation. The use of these agents involves potential bleeding complications, particularly during invasive procedures. With increasing use of DOACs, adequate knowledge regarding the perioperative management of patients on DOACs has become indispensable. Read More

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http://dx.doi.org/10.1080/14656566.2018.1551879DOI Listing
March 2019
4 Reads

A review and analysis of strategies for prediction, prevention and management of post-operative atrial fibrillation after non-cardiac thoracic surgery.

J Thorac Dis 2018 Nov;10(Suppl 32):S3799-S3808

Division of Thoracic Surgery, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada.

Atrial fibrillation (AF) is the most common sustained arrhythmia after non-cardiac thoracic surgery and is associated with a significant increase in perioperative morbidity, intensive care unit (ICU) admission, and mortality. Practical guidance is needed to assist clinicians in managing this critical issue and direct further research. Here we aim to provide a synoptic review and analysis of the literature to distil practical recommendations for prediction, prevention and management of post-operative atrial fibrillation (POAF) suitable for clinical application and further evaluation. Read More

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http://dx.doi.org/10.21037/jtd.2018.09.144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258651PMC
November 2018
2 Reads

Prothrombin Complex Concentrates for Warfarin Reversal Prior to Heart Transplantation.

Ann Thorac Surg 2018 Nov 23. Epub 2018 Nov 23.

Department of Cardiothoracic Surgery, New York University Langone Health.

Background: Anticoagulation with warfarin is common prior to heart transplantation and complicates perioperative management.

Methods: This single-center, non-interventional, retrospective cohort study evaluated heart transplants before and after institution of a PCC-based preoperative warfarin reversal protocol for heart transplantation. Patients with international normalized ratio (INR) > 1. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2018.10.032DOI Listing
November 2018
4 Reads

Risk assessment and management of preoperative venous thromboembolism following femoral neck fracture.

J Orthop Surg Res 2018 Nov 20;13(1):291. Epub 2018 Nov 20.

Department of Orthopaedics, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Wangfujing, Dongcheng District, Beijing, 100730, People's Republic of China.

Background: Limited studies are available to investigate the prevalence of preoperative venous thromboembolism (VTE) in elderly patients with femoral neck fractures. Our primary aim was to determine the incidences of VTE and its risk or protective factors in such patient population. The secondary objective was to evaluate the need of therapeutic anticoagulation for isolated calf muscular venous thrombosis (ICMVT) prior to femoral neck fracture surgery. Read More

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http://dx.doi.org/10.1186/s13018-018-0998-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245713PMC
November 2018
3 Reads

MCA-to-MCA Bypass with Interposition Graft for Ruptured Mycotic Middle Cerebral Artery Aneurysm.

World Neurosurg 2019 Feb 2;122:195. Epub 2018 Nov 2.

Department of Neurosurgery, Sanbo Brain Hospital, Capital Medical University, Beijing, People's Republic of China. Electronic address:

Mycotic aneurysm, also referred to as infected aneurysm, is a rare entity that may result from the bacterial infection or infective endocarditis. The treatment options include conservative medication and endovascular or direct microsurgical intervention. However, the optimal strategy remains unknown and cerebral revascularization may be required in some rare cases. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.10.167DOI Listing
February 2019
1 Read

Preoperative Management of Medications.

Anesthesiol Clin 2018 Dec;36(4):663-675

Department of Anesthesiology and Perioperative Medicine, Centro de Desarrollo de Destrezas Medicas, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Vaco de Quiroga #15, Col. Belisario Dominguez Sección XVI, Mexico City 14080, Mexico.

Increasingly complex medication regimens for many comorbidities in patients for planned surgical and procedural interventions necessitate detailed preoperative evaluation of the pharmacologic therapy, including the indications, the specific drugs, and dosing amount and interval. The implications of continuing or withholding these agents in the perioperative period need to be elucidated, as well as the risks of interactions and side effects. A comprehensive plan of the management of the therapeutic agents should be devised during the preoperative visit, with input from all relevant specialists, and clearly communicated to the patients in a format that ensures their comprehension and consistent compliance. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19322275183007
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http://dx.doi.org/10.1016/j.anclin.2018.07.012DOI Listing
December 2018
14 Reads

Laparoscopic procedures in patients with cardiac ventricular assist devices.

Surg Endosc 2018 Oct 26. Epub 2018 Oct 26.

Department of Surgery, University of Chicago, 5841 S Maryland Ave, Chicago, IL, 60637, USA.

Background: Cardiac left ventricular assist device (LVAD) placement is a common therapy for heart failure. Non-cardiac surgical care of these patients can be complex given the need for anticoagulation, perioperative monitoring, comorbidities, and anatomical considerations due to the device itself. There are no guidelines or significant patient series reported to date for laparoscopic procedures in this population. Read More

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http://link.springer.com/10.1007/s00464-018-6497-1
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http://dx.doi.org/10.1007/s00464-018-6497-1DOI Listing
October 2018
20 Reads

[A case of systemic lupus erythematosus in pregnancy complicated by pulmonary hypertension].

Beijing Da Xue Xue Bao Yi Xue Ban 2018 Oct;50(5):928-931

Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China.

To investigate the pathophysiology, screening, diagnosis and treatment of the systemic lupus erythematosus (SLE) in pregnancy complicated with pulmonary hypertension. Retrospective analysis was made of one case of SLE in pregnancy complicated with pulmonary hypertension in Peking University Third Hospital. Literature was reviewed to investigate the pathophysiology, screening, diagnosis and treatment of the SLE in pregnancy complicated with pulmonary hypertension. Read More

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October 2018
19 Reads

Survey of the management of perioperative bridging of anticoagulation and antiplatelet therapy in neurosurgery.

Acta Neurochir (Wien) 2018 Nov 20;160(11):2077-2085. Epub 2018 Sep 20.

Department of Neurosurgery, University Hospital Tuebingen, Eberhard Karls University Tuebingen, Hoppe-Seyler-Straße 3, 72076, Tuebingen, Germany.

Background: A growing number of patients on anticoagulation or antiplatelet therapy (APT) are planned for elective surgery. The management of perioperative anticoagulation and APT is challenging because it must balance the risk of thromboembolism and bleeding, and specific recommendations for the management of bridging in neurosurgical patients are lacking. We surveyed German neurosurgical centers about their management of perioperative bridging of anticoagulation and APT to provide an overview of the current bridging policy. Read More

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http://dx.doi.org/10.1007/s00701-018-3679-5DOI Listing
November 2018
4 Reads

Current practices in microvascular reconstruction in otolaryngology-head and neck surgery.

Laryngoscope 2019 Jan 8;129(1):138-145. Epub 2018 Sep 8.

Department of Otolaryngology-Head and Neck Surgery, Michigan Medicine, Ann Arbor, Michigan, U.S.A.

Objectives/hypothesis: Despite major advances in the field of head and neck microvascular free tissue transfer (MFTT) over the past several decades, there are no standardized perioperative regimens for the care of patients undergoing free flap reconstructive surgery, and continued variation in practice exists. This study aimed to report current trends in the field of MFTT performed by otolaryngologists, including surgeon training, institutional operative practices, and perioperative management.

Study Design: Cross-sectional survey. Read More

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http://dx.doi.org/10.1002/lary.27257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320283PMC
January 2019
8 Reads

Nutrition and Perioperative Care for the Patient with Head and Neck Cancer.

Oral Maxillofac Surg Clin North Am 2018 Nov 31;30(4):411-420. Epub 2018 Aug 31.

Department of Otolaryngology-Head and Neck Surgery, UC Davis School of Medicine, Sacramento, CA, USA. Electronic address:

Recovery after major head and neck cancer surgery is a complex process. In addition to perioperative sequelae such as pain, wound infections, venous thromboembolism (VTE), and pneumonia, these patients frequently suffer from malnutrition. We provide a contemporary evidence-based approach to common aspects of perioperative care to guide the clinician in the optimal management of patients. Read More

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http://dx.doi.org/10.1016/j.coms.2018.06.003DOI Listing
November 2018
4 Reads

Antithrombotic therapy management of adult and pediatric cardiac surgery patients.

J Thromb Haemost 2018 Nov 30;16(11):2133-2146. Epub 2018 Sep 30.

University of Alberta, Department of Pediatrics, Edmonton, Alberta, Canada.

Despite the development of catheter-based interventions for ischemic and valvular heart disease, hundreds of thousands of people undergo open heart surgery annually for coronary artery bypass graft (CABG), valve replacement or cardiac assist device implantation. Cardiac surgery patients are unique because therapeutic anticoagulation is required during cardiopulmonary bypass. Developmental hemostasis and altered drug metabolism affect management in children. Read More

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http://doi.wiley.com/10.1111/jth.14276
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http://dx.doi.org/10.1111/jth.14276DOI Listing
November 2018
8 Reads

A Narrative Review for Perioperative Physicians of the 2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants.

J Cardiothorac Vasc Anesth 2019 02 20;33(2):290-301. Epub 2018 Jul 20.

Miller School of Medicine, University of Miami, Miami, FL.

In 2017 the American College of Cardiology issued an Expert Consensus Decision Pathway dedicated specifically to the management of bleeding in patients on anticoagulants. The consensus document is both timely and important as indications for more novel anticoagulants expand rapidly. The document reviews in detail recommendations for interruption, management and re-initiation of anticoagulation in bleeding scenarios. Read More

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http://dx.doi.org/10.1053/j.jvca.2018.07.023DOI Listing
February 2019
6 Reads

Antithrombotic Therapy after Bioprosthetic Aortic Valve Replacement: A Therapeutic Morass.

Cardiology 2018 23;140(4):213-221. Epub 2018 Aug 23.

Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut, USA.

Valvular heart disease is a common pathologic condition that affects 6 million people in the United States and more than 100 million worldwide. The most common valvular disorder is aortic stenosis. Current American and European guidelines recommend surgical management for symptomatic aortic stenosis with low risk of perioperative complications and endovascular intervention for high-risk patients with multiple comorbidities. Read More

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http://dx.doi.org/10.1159/000490924DOI Listing
August 2018
7 Reads

Perioperative considerations in free flap surgery: A review of pressors and anticoagulation.

Oral Oncol 2018 Aug 28;83:154-157. Epub 2018 Jun 28.

Oregon Health and Sciences University, Department of Otolaryngology-HNS, United States.

Given the high stakes for microvascular reconstruction, the majority of reconstructive surgeons have developed paradigms for pre, intra, and postoperative management that have proven to result in individual high success rates. Much has been done to identify and avoid perioperative factors that could potentially increase flap failure rates. Two example of this practice has been the generalized use of anticoagulation in free tissue transfer and the prohibition against vasopressor use in patients that are undergoing free tissue transfer. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13688375183024
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http://dx.doi.org/10.1016/j.oraloncology.2018.06.025DOI Listing
August 2018
37 Reads

Perioperative coagulation management: Evolving strategies.

Authors:
Jerrold H Levy

Anaesth Crit Care Pain Med 2018 08;37(4):317-318

Department of Anesthesiology, Critical Care Medicine, and Surgery (Cardiothoracic), Duke University School of Medicine, Duke University Medical Center, 2301 Erwin Rd, Box 3094, 27710 Durham, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.accpm.2018.07.002DOI Listing
August 2018
10 Reads

Perioperative interruption of direct oral anticoagulants in patients with atrial fibrillation: A systematic review and meta-analysis.

Res Pract Thromb Haemost 2018 Apr 16;2(2):282-290. Epub 2018 Feb 16.

Department of Medicine Ottawa Hospital Research Institute at the University of Ottawa Ottawa ON Canada.

Background: Patients with atrial fibrillation (AF) frequently undergo invasive procedures that require temporary interruption of anticoagulation. There is little evidence to guide the perioperative interruption of direct oral anticoagulants (DOACs).

Methods: A systematic literature search including studies that evaluated the perioperative interruption of DOACs for non-emergent invasive procedures in patients with AF was performed. Read More

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http://doi.wiley.com/10.1002/rth2.12076
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http://dx.doi.org/10.1002/rth2.12076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055497PMC
April 2018
6 Reads

[Oral Anticoagulants: Management of Elective and Emergency Surgery].

Anasthesiol Intensivmed Notfallmed Schmerzther 2018 Jul 23;53(7-08):543-550. Epub 2018 Jul 23.

In most patients, oral anticoagulation is performed with vitamin K antagonists (VKA) or non-vitamin K antagonist oral anticoagulants (NOAC). Because of a long half-life, VKA are dosed by measuring INR. In standard cases coagulation tests for NOAC are not necessary; application is performed in a fixed dose. Read More

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http://dx.doi.org/10.1055/s-0043-111006DOI Listing
July 2018
10 Reads

Periprocedural management of patients with subarachnoid hemorrhage.

Curr Opin Anaesthesiol 2018 Oct;31(5):511-519

Department of Anaesthesia and Critical Care Medicine, 'Sapienza' University, Rome, Italy.

Purpose Of Review: Anesthesiologists and intensivists may be involved in the management of aneurysmal subarachnoid hemorrhage (aSAH) patients at various stages of care. This article will review the recent advances in the periprocedural management of aSAH patients.

Recent Findings: New scoring systems to assess gravity and prognosis of aSAH patients have been evaluated and proposed. Read More

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http://dx.doi.org/10.1097/ACO.0000000000000627DOI Listing
October 2018
6 Reads

Perioperative Management of New Oral Anticoagulants in Urological Surgery.

Curr Urol 2018 Jun 30;11(4):169-174. Epub 2018 Mar 30.

Department of Urology and Transplantation, Beaumont Hosiptal, Dublin, Ireland.

New oral anticoagulants (NOACs) are increasingly replacing the use of warfarin in clinical practice. Their use has now also been extended to thromboprophylaxis in many orthopedic surgeries. This, in addition to an increasingly aging population with many complex comorbidities means that these medications will be ever more frequently encountered by urologists. Read More

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http://dx.doi.org/10.1159/000447214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036579PMC
June 2018
2 Reads

Management of cardiac tamponade during catheter-directed thrombolysis of saddle pulmonary embolism: A clinical dilemma.

Lung India 2018 Jul-Aug;35(4):336-338

Department of Radiology, Medical College of Georgia, Augusta University, Augusta, GA, USA.

Catheter-directed thrombolysis (CDT) for the treatment of acute pulmonary embolism (PE) has gained popularity in recent years, but potential complications during the procedure and their management are not frequently discussed in the literature. In this case report, we describe the clinical dilemma regarding the postoperative anticoagulation management of a 60-year-old male who developed cardiac perforation during a CDT of an acute saddle PE. Early resumption of systemic heparin in such cases may help in clot resolution; however, it can worsen the hemopericardium. Read More

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http://dx.doi.org/10.4103/lungindia.lungindia_383_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034378PMC
July 2018
10 Reads

[Bridging anticoagulation in patients receiving vitamin K antagonists : Current status].

Internist (Berl) 2018 07;59(7):744-752

Klinik für Gefäßmedizin - Angiologie, Klinikum Darmstadt GmbH, Darmstadt, Deutschland.

Approximately 30% of patients receiving oral anticoagulation using vitamin K antagonists (VKA) require surgery within 2 years. In this context, a clinical decision on the need and the mode of a peri-interventional bridging with heparin is needed. While a few years ago, bridging was almost considered a standard of care, recent study results triggered a discussion on which patients will need bridging at all. Read More

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http://dx.doi.org/10.1007/s00108-018-0447-9DOI Listing
July 2018
4 Reads

Validation of a New Small-Volume Sodium Citrate Collection Tube for Coagulation Testing in Critically Ill Patients with Coagulopathy.

Clin Lab 2018 06;64(6):1083-1089

Background: Blood loss due to phlebotomy leads to hospital-acquired anemia and more frequent blood transfusions that may be associated with increased risk of morbidity and mortality in critically ill patients. Multiple blood conservation strategies have been proposed in the context of patient blood management to minimize blood loss. Here, we evaluated a new small-volume sodium citrate collection tube for coagulation testing in critically ill patients. Read More

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http://dx.doi.org/10.7754/Clin.Lab.2018.171008DOI Listing
June 2018
8 Reads

The study protocol for PREDICT AF RECURRENCE: a PRospEctive cohort stuDy of surveIllanCe for perioperaTive Atrial Fibrillation RECURRENCE in major non-cardiac surgery for malignancy.

BMC Cardiovasc Disord 2018 06 26;18(1):127. Epub 2018 Jun 26.

Division of Cardiology, Department of Internal Medicine II, Kyorin University School of Medicine, Tokyo, Japan.

Background: A previous retrospective cohort study established the relationship between perioperative atrial fibrillation (POAF) and subsequent mortality and stroke. However, the details regarding the cause of death and etiology of stroke remain unclear.

Methods: The prospective cohort study of surveillance for perioperative atrial fibrillation recurrence in major non-cardiac surgery for malignancy (PREDICT AF RECURRENCE) registry is an ongoing prospective cohort study to elucidate the long-term recurrence rate and the clinical impact of new-onset POAF in the setting of head and neck, non-cardiac thoracic, and abdominal surgery for malignancy. Read More

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http://dx.doi.org/10.1186/s12872-018-0862-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019832PMC
June 2018
6 Reads

Perioperative Safety and Efficacy of Different Anticoagulation Strategies With Direct Oral Anticoagulants in Pulmonary Vein Isolation: A Meta-Analysis.

JACC Clin Electrophysiol 2018 Jun;4(6):794-806

Department of Medicine and Surgery, University of Insubria, Varese, Italy. Electronic address:

Objectives: The purpose of this study was to evaluate the safety and efficacy of uninterrupted and interrupted direct oral anticoagulant (DOAC) administration in patients undergoing pulmonary vein isolation (PVI).

Background: The optimal periprocedural management of DOACs in patients undergoing PVI is not well defined, and different strategies are used.

Methods: A systematic search of PubMed/MEDLINE, Ovid/MEDLINE, and EMBASE was performed. Read More

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http://dx.doi.org/10.1016/j.jacep.2018.04.006DOI Listing
June 2018
5 Reads

[Bridging anticoagulation in patients receiving vitamin K antagonists : Current status].

Anaesthesist 2018 Aug;67(8):599-606

Klinik für Gefäßmedizin - Angiologie, Klinikum Darmstadt GmbH, Darmstadt, Deutschland.

Approximately 30% of patients receiving oral anticoagulation using vitamin K antagonists (VKA) require surgery within 2 years. In this context, a clinical decision on the need and the mode of a peri-interventional bridging with heparin is needed. While a few years ago, bridging was almost considered a standard of care, recent study results triggered a discussion on which patients will need bridging at all. Read More

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http://dx.doi.org/10.1007/s00101-018-0463-0DOI Listing
August 2018
2 Reads

A meta-analysis of randomized controlled trials of uninterrupted periprocedural anticoagulation strategy in patients undergoing atrial fibrillation catheter ablation.

Int J Cardiol 2018 Nov 8;270:167-171. Epub 2018 Jun 8.

Pharmaceutical College, Guangxi Medical University, China.

Background: In patients undergoing atrial fibrillation (AF) ablation, despite uninterrupted oral anticoagulants (OACs) have been recommended, no consensus has emerged regarding to whether uninterrupted novel oral anticoagulants (NOACs) are superior to uninterrupted vitamin K antagonists (VKAs) for the periprocedural antithrombotic management. This meta-analysis aimed to compare the efficacy and safety of uninterrupted NOACs and uninterrupted VKAs in patients undergoing AF ablation.

Methods: Databases were searched for articles published up to March 20, 2018. Read More

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http://dx.doi.org/10.1016/j.ijcard.2018.06.024DOI Listing
November 2018
26 Reads

Perioperative and Periprocedural Management of Antithrombotic Therapy: Consensus Document of SEC, SEDAR, SEACV, SECTCV, AEC, SECPRE, SEPD, SEGO, SEHH, SETH, SEMERGEN, SEMFYC, SEMG, SEMICYUC, SEMI, SEMES, SEPAR, SENEC, SEO, SEPA, SERVEI, SECOT and AEU.

Rev Esp Cardiol (Engl Ed) 2018 Jul 8;71(7):553-564. Epub 2018 Jun 8.

Área de Enfermedades del Corazón, Hospital Universitario de Bellvitge-IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain.

During the last few years, the number of patients receiving anticoagulant and antiplatelet therapy has increased worldwide. Since this is a chronic treatment, patients receiving it can be expected to need some kind of surgery or intervention during their lifetime that may require treatment discontinuation. The decision to withdraw antithrombotic therapy depends on the patient's thrombotic risk versus hemorrhagic risk. Read More

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http://dx.doi.org/10.1016/j.rec.2018.01.029DOI Listing
July 2018
27 Reads

The Use of Cangrelor and Heparin for Anticoagulation in a Patient Requiring Pulmonary Thromboendarterectomy Surgery with Suspected Heparin-Induced Thrombocytopenia.

J Cardiothorac Vasc Anesth 2019 Apr 30;33(4):1050-1053. Epub 2018 Apr 30.

Sulpizio Cardiovascular Center, University of California San Diego, La Jolla, CA.

The management of heparin-induced thrombocytopenia (HIT) in the perioperative period for patients undergoing cardiac surgery requiring cardiopulmonary bypass (CPB) and deep hypothermic circulatory arrest (DHCA) can be a challenging clinical scenario. Once a diagnosis of HIT has been established, heparin products typically are avoided and alternative therapies for anticoagulation are started. Alternative anticoagulation strategies for CPB are limited and often have various pharmacokinetic profiles that may lead to increased perioperative bleeding. Read More

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http://dx.doi.org/10.1053/j.jvca.2018.04.051DOI Listing
April 2019
8 Reads

Guideline Implementation: Prevention of Venous Thromboembolism: 1.6 www.aornjournal.org/content/cme.

Authors:
Terri Link

AORN J 2018 Jun;107(6):737-748

Venous thromboembolism (VTE) is a serious and costly complication of surgery. Many cases of health care-associated VTE could be prevented with the use of evidenced-based interventions. Perioperative nurses are in a position to advocate for patients by assessing each patient's risk for VTE and implementing preventive measures, such as administering anticoagulants as ordered and correctly applying graduated compression stockings and intermittent pneumatic compression devices. Read More

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http://dx.doi.org/10.1002/aorn.12146DOI Listing
June 2018
21 Reads

Early surgical treatment in patients with pulmonary embolism and thrombus-in-transit.

J Thorac Dis 2018 Apr;10(4):2338-2345

Venous Thromboembolism Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Background: Floating right heart thrombi (RHT) are in transit from the legs to the pulmonary arteries and thus are a severe form of venous thromboembolism (VTE), with a high early mortality rate without treatment. There is a lack of evidence-based recommendations for its management. The objective of this study is to describe our experience in the surgical management of thrombus-in-transit and pulmonary embolism (PE) in a tertiary hospital. Read More

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http://dx.doi.org/10.21037/jtd.2018.04.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949483PMC
April 2018
5 Reads

Plasmapheresis for Management of Antiphospholipid Syndrome in the Neurosurgical Patient.

Oper Neurosurg (Hagerstown) 2019 Apr;16(4):E124-E129

Department of Neurological Surgery, Washington University School of Medicine, St. Louis, Missouri.

Background And Importance: Antiphospholipid syndrome (APS) is an autoimmune disorder associated with a hypercoagulable state and increased risk of intraoperative and postoperative thrombosis. Few neurosurgical studies have examined the management of these patients, though the standard of care in most other disciplines involves the use of anticoagulation therapy. However, this is associated with risks such as hemorrhage, thrombosis due to warfarin withdrawal, and is not compatible with operative intervention. Read More

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http://dx.doi.org/10.1093/ons/opy135DOI Listing
April 2019
5 Reads

ECMO for Acute Respiratory Distress Syndrome After Thoracoabdominal Aortic Aneurysm Repair.

Ann Thorac Surg 2018 Oct;106(4):e171-e172

Department of Surgery, Division of Cardiothoracic Surgery, Baylor College of Medicine, Houston, Texas.

Acute respiratory distress syndrome (ARDS) after thoracoabdominal aortic aneurysm (TAAA) repair poses a formidable challenge. Despite conventional maneuvers in the operating room, perioperative ARDS may require extracorporeal membrane oxygenation (ECMO). We present three cases of successful ECMO for ARDS after TAAA repair and discuss management of anticoagulation and cerebrospinal fluid drains. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00034975183067
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http://dx.doi.org/10.1016/j.athoracsur.2018.04.045DOI Listing
October 2018
12 Reads
3.850 Impact Factor

[Management of anticoagulants in ophthalmic surgery-a survey among ophthalmic surgeons in Germany].

Ophthalmologe 2018 May 16. Epub 2018 May 16.

Gerinnungsambulanz und Hämophiliezentrum an der Charité, Berlin, Deutschland.

Introduction: As our population ages and comorbidities rise, ophthalmic surgeons are increasingly faced with patients on anticoagulant therapy or with clotting disorders. The ophthalmic surgeon has to weigh the perioperative risk of haemorrhage when anticoagulation continues against the risk of thromboembolism caused by discontinuation or changing the patient's medication (bridging, switching, cessation). There are currently no guidelines or recommendations. Read More

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http://dx.doi.org/10.1007/s00347-018-0732-yDOI Listing
May 2018
7 Reads

[Oral anticoagulation : Current overview and perioperative management in ophthalmic surgery].

Ophthalmologe 2019 Feb;116(2):144-151

Augenklinik, Universitätsmedizin Göttingen, Göttingen, Deutschland.

Antithrombotic treatment with oral anticoagulants and antiplatelet agents can increase the risk for perioperative bleeding. In contrast to other surgical fields, the optimal perioperative management in ophthalmic surgery has not yet been exactly defined and, thus, is not standardized. In this contribution, we provide an overview of currently available oral anticoagulants and discuss potential strategies for the management of these agents in different ophthalmic surgical procedures. Read More

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http://dx.doi.org/10.1007/s00347-018-0724-yDOI Listing
February 2019
4 Reads