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Forensic Sci Med Pathol 2018 Nov 29. Epub 2018 Nov 29.

University of North Dakota School of Medicine and Health Sciences, 1301 N. Columbia Rd (Room W430), Grand Forks, ND, 58203, USA.

Kratom is a plant with dose-dependent mixed stimulant and opioid properties whose pharmacologic characteristics and social impact continue to be described. The main active isolate of kratom is mitragynine, an indole-containing alkaloid with opioid-like effects. Kratom toxicity and kratom-associated fatalities have been described, including those in association with additional drugs. Read More

J Obstet Gynaecol Res 2018 Nov 22. Epub 2018 Nov 22.

Department of Obstetrics and Gynecology, Hyogo College of Medicine, Nishinomiya, Japan.

Resuscitative hysterotomy (RH) is a resuscitation technique, allowing the restoration of a pregnant patient's heartbeat. Here, we reported a case of RH performed in a patient with cardiac arrest as a complication of a peripartum cardiomyopathy. A 29-year-old woman with suspected hemolysis, elevated liver enzymes, low platelet syndrome was admitted to the hospital. Read More

Forensic Sci Med Pathol 2018 Dec 13;14(4):484-496. Epub 2018 Nov 13.

Department of Forensic Medicine and Imaging, Institute of Forensic Medicine, University of Zurich, Winterthurerstrasse 190/52, CH-8057, Zurich, Switzerland.

During hanging gravitational forces affect the spine. Intervertebral vacuum phenomenon (VP) implies that gas accumulations in the discs are caused by degeneration of the spine and trauma. It was hypothesized that VP detected on postmortem computed tomography (PMCT) has a higher incidence in hanging deaths, which can be correlated to age, degenerative spinal changes and type of hanging (complete-incomplete). Read More

Int J Legal Med 2018 Oct 30. Epub 2018 Oct 30.

Forensic Anthropology Unit, Institut de Medicina Legal i Cienciès Forense (IMLCFC), Ciutat de la Justícia, Gran Via de les Corts Catalanes, 111 Edifici G, 08075, Barcelona, Spain.

This study aims to improve a previous study that reported new traits to characterize a perimortem fracture pattern in human long bones. This second study aims to acquire further knowledge about these perimortem traits, specifically by improving the experimental setting-by using a Blunt Force Trauma Simulator-and increasing the sample size with a total of 43 autopsy specimens and 57 reproduced fractures. Additionally, we investigated whether these traits could be related to muscular contractions by adding axial compression in the experimentally fractured specimens. Read More

Anthropol Anz 2018 Oct 26. Epub 2018 Oct 26.

Department of Advanced Biomedical Sciences, Azienda Ospedaliera Universitaria Federico II, Via Pansini 5, 80131 Naples, Italy.

Finding traumatic lesions on ancient skeletal remains offers a unique opportunity to investigate the circumstances surrounding the time of death. Here we present the unique find of a late 17, early 18 century young male from Southern Italy with eight traumatic skull lesions. A detailed anthropological examination using X-ray and 3D CT scanning techniques was conducted in order to evaluate traumatic extent, direction and degree of severity of each skull injury. Read More

Forensic Sci Int 2018 Sep 3. Epub 2018 Sep 3.

Department of Anthropology, National Museum of Natural History, Smithsonian Institution, Washington, D.C. USA. Electronic address:

This special issue of Forensic Science International presents diverse perspectives and detailed information on the many factors involved in trauma analysis of the skeleton. Topics covered include nomenclature, antemortem timing, post-mortem loss of plasticity, terminal ballistic/gunshot trauma, sharp force trauma, heat-induced fracture, non-metric traits and pseudo-trauma, taphonomic alterations, microscopic evidence for hemorrhage, imaging of perimortem trauma, dental trauma and linkages between soft and hard tissue. Read More

J Obstet Gynaecol Res 2018 Sep 25. Epub 2018 Sep 25.

Department of Maternal and Fetal Medicine, Miyagi Children's Hospital, Sendai, Japan.

Aim: Perimortem cesarean section (PCS) is a procedure performed as part of cardiopulmonary resuscitation (CPR). This study aims to clarify maternal and neonatal prognosis and establish PCS's utility and limitations.

Methods: We sent structured questionnaires to obstetrics facilities regarding the cases of PCS performed in Japan between April 2010 and April 2015. Read More

J Matern Fetal Neonatal Med 2018 Sep 23:1-3. Epub 2018 Sep 23.

a Department of Maternal-Neonatal Care , DAIMI, Careggi University Hospital , Florence , Italy.

Cardiac arrest in pregnancy is a rare event due to different cause. When it occurs after spinal anesthesia a cause that can explain this event is the Bezold-Jarish Reflex (BJR). A cardiac arrest occurs in a pregnant women after spinal anesthesia admistered for urgent caesarean section. Read More

Int J Paleopathol 2018 Sep 20;24:7-18. Epub 2018 Sep 20.

Memorial University of Newfoundland, Department of Archaeology, Queen's College, 210 Prince Philip Drive, St. John's NL A1B 3R6, Canada; McMaster University, Department of Anthropology, Chester New Hall, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada. Electronic address:

Investigating injury recidivism and individuals with multiple injuries is an area of growing interest in bioarchaeology. Differentiating between whether an individual sustained multiple injuries, represented by antemortem healed fractures, in one incident or in multiple incidents over the life course, is a major challenge. This research analyzed the skeletal remains of 721 adults (402 males, 319 females) from five post-medieval cemeteries from London, UK, known to include working class individuals for evidence of skeletal trauma - fractures, myositis ossificans, subluxations/dislocations, blunt force trauma, and sharp force trauma. Read More

J Forensic Sci 2018 Sep 19. Epub 2018 Sep 19.

C.A. Pound Human Identification Laboratory, Department of Anthropology, University of Florida, 2033 Mowry Road Room G-17, Gainesville, FL, 32610.

The decomposed body of a woman discovered beneath a collapsed structure was examined at the C.A. Pound Human Identification Laboratory. Read More

Sci Adv 2018 Sep 12;4(9):eaat6925. Epub 2018 Sep 12.

Institute of Zoology, Zoological Society of London, Regent's Park, London NW1 4RY, UK.

Previous research suggests that people first arrived on Madagascar by ~2500 years before present (years B.P.). Read More

Am J Phys Anthropol 2018 Nov 29;167(3):615-627. Epub 2018 Aug 29.

Departamento de Geodinámica, Estratigrafía y Paleontología, Facultad de Ciencias Geológicas, Universidad Complutense de Madrid, Madrid, Spain.

Objectives: The aim of this work is to describe the taphonomic signatures of the Aroeira 3 cranium, with a specific focus on cranial breakage, comparing the cranium with other Middle and Upper Pleistocene hominin fossils in order to approximate the cause of death and the biological agencies and geologic processes involved in the taphonomic record of this specimen. Aroeira-3 was recovered from Acheulean layer X of Gruta da Aroeira (Portugal), dated to 390-436 ka.

Materials And Methods: Taphonomic analyses noted surface modifications employing standard methods. Read More

APMIS 2018 Jul;126(7):626-637

Department of Pathology, Cork University Hospital, Cork, Ireland.

Twin placentas are frequently received in pathology laboratories for evaluation of chorionicity and because twin pregnancies have higher rates of pregnancy complications. In addition to pathologies common in singleton pregnancies, twin pregnancies have increased frequencies of complications such as preterm birth and velamentous cord insertions and also are affected by complications unique to multiple pregnancies that are mediated by vascular connections between the placental territories of certain types of twins. This article aims to provide an approach to examination of the twin placenta for practicing pathologists or those interested in placental pathology while outlining the key characteristics of twin complications as seen in the placenta. Read More

Int J Paleopathol 2018 Sep 17;22:189-197. Epub 2018 Jul 17.

Faculty of Medicine, Vilnius University, Vilnius, Lithuania.

The aim of this article was to describe the outcome of a probable case of physical abuse in the remains of a child dating from the 16-18 centuries CE. The skeleton of a subadult was recovered during archaeological excavations carried out in the village of Užubaliai, located in Alytus in southern Lithuania, and subsequently curated in the Faculty of Medicine at Vilnius University. The bones of this child were observed macroscopically and then submitted for radiological investigation. Read More

J Perinat Neonatal Nurs 2018 Jul/Sep;32(3):212-221

Cypher Maternal Fetal Solutions, Gig Harbor, Washington.

From the periphery, pregnancy is a common event in women of childbearing age. Normal anatomic and physiologic adaptations occur and, in most cases, will result in ideal maternal-fetal outcomes. Yet, every day, obstetric clinicians are facing complex pregnancies with complicated life-threatening conditions or coexisting medical and surgical problems that not only alter maternal physiology but also impact fetal survival. Read More

Curr Treat Options Cardiovasc Med 2018 Jun 19;20(7):57. Epub 2018 Jun 19.

Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, Bethesda, USA.

Purpose Of Review: The goal of this review is to elucidate what is known about the science of maternal resuscitation and how treatment guidelines have developed to optimize management.

Recent Findings: There is limited data on maternal cardiac arrest. Case reports are providing some insight into safety and efficacy of certain mechanisms of treatment, including use of extracorporeal membranous oxygenation and thrombolysis, for example. Read More

Eur J Obstet Gynecol Reprod Biol 2018 Sep 11;228:32-37. Epub 2018 Jun 11.

Department of Obstetrics and Gynecology, School of Medicine, Fukushima Medical University, Fukushima, Japan.

Objective: Histological chorioamnionitis (CAM) is related to neonatal mortality and morbidity. However, identifying intrauterine inflammation before delivery is challenging. The aim of this study was to investigate the changes in fetal heart rate (FHR) short-term variability (STV) during the course of histological CAM. Read More

Forensic Sci Int 2018 Aug 4;289:e18-e23. Epub 2018 Jun 4.

Department of Legal and Forensic Medicine, University of Genova, Via De Toni 12, 16132 Genova, Italy. Electronic address:

The present study reports the mycological data collected from two corpses preserved in controlled conditions and monitored for 6 weeks at the mortuary. On the whole during the monitoring more than 70 fungal CFU (Colony Forming Units) were sampled from the corpses. The data collected were used to map the body fungal colonization of the corpses during 6 weeks. Read More

J Obstet Gynaecol India 2018 Jun 26;68(3):155-163. Epub 2018 Mar 26.

2Department of Anaesthesiology, Pain & Critical Care, AFMC, Pune, India.

Maternal mortality is disastrous news for the society, family, newborn, and the obstetrician. Yet, we all who are care providers to these apparently healthy women carrying another life within them are dumbfounded by the clinical conditions arising due to the pregnancy or the effects of the pregnancy, that it becomes difficult to provide an ideal care to them. The rapid uprising of a condition and the worsening of commonly occurring benign conditions-preeclampsia, hemorrhage, etc. Read More

Anthropol Anz 2018 08;75(3):243-249

Department of Anatomy, Histology and Anthropology, Faculty of Medicine, Vilnius University, M.K. Čiurlionis street 21, 03101 Vilnius, Lithuania.

Abstract: Skeletal evidence of beheading in early modern Lithuania has been scarce, despite historical documentation indicating it as a popular practice. This study presents the first bioarchaeological cases of decapitation in early modern Lithuania, with four adult male individuals from the 14-17 centuries A.D. Read More

World Neurosurg 2018 Aug 17;116:116-120. Epub 2018 May 17.

Division of Paleopathology, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy.

During the archaeological excavations conducted in the Hellenistic necropolis discovered in Messina (Sicily, Italy) dating back to the 3rd century BC., a skeleton showing evidence of cranial traumas and surgical intervention was found. The skull, belonging to a young adult male, presented signs of 4 head injuries produced by both blunt and sharp-edged instruments. Read More

Prostate 2018 Jul 26;78(10):714-723. Epub 2018 Mar 26.

The James and Eilleen Dicke Laboratory, Department of Urology, Case Western Reserve University, Cleveland, Ohio.

Background: We previously demonstrated that adenosine monophosphate-activated protein kinase (AMPKα) activity is significantly inhibited by Ser-486/491 phosphorylation in cell culture and in vivo models of metastatic and castration-resistant prostate cancer, and hypothesized these findings may translate to clinical specimens.

Methods: In this retrospective, single-institution pilot study, 45 metastatic prostate cancer cases were identified within the University Hospitals Cleveland Medical Center Pathology Archive with both metastasis and matched primary prostate tumor specimens in formalin-fixed, paraffin-embedded blocks, and complete electronic medical records. Thirty non-metastatic, hormone-dependent prostate cancer controls, who were progression-free as defined by undetectable prostate specific antigen for at least 79. Read More

J Hum Evol 2018 Apr 21;117:13-32. Epub 2018 Feb 21.

Équipe de Paléontologie Humaine, UMR 7194, CNRS, Département Homme et Environnement, Muséum national d'Histoire naturelle, Musée de l'Homme, 17, Place du Trocadéro, 75016 Paris, France; Department of African Zoology, Royal Museum for Central Africa, Tervuren, Belgium.

The La Ferrassie 1 (LF1) skeleton, discovered over a century ago, is one of the most important Neandertal individuals both for its completeness and due to the role it has played historically in the interpretation of Neandertal anatomy and lifeways. Here we present new skeletal remains from this individual, which include a complete right middle ear ossicular chain (malleus, incus, and stapes), three vertebral fragments, and two costal remains. Additionally, the study of the skeleton has allowed us to identify new pathological lesions, including a congenital variant in the atlas, a greenstick fracture of the left clavicle, and a lesion in a mid-thoracic rib of unknown etiology. Read More

Int J Legal Med 2018 Jul 3;132(4):1205-1213. Epub 2018 Mar 3.

Forensic Anthropology Unit, Institut de Medicina Legal i Cienciès Forense (IMLCFC), Ciutat de la Justícia, Gran Via de les Corts Catalanes, 111 Edifici G, 08075, Barcelona, Spain.

Literature on timing of rib trauma is scarce but remains challenging during forensic cases. This study analysed the macroscopic fracture patterns of perimortem rib fractures and compared them to experimentally reproduced rib fractures on fresh and dry ribs. Six distinctive macroscopic traits were found in ribs that might provide information about the timing of trauma, fracture mechanism and/or trauma circumstances. Read More

Int J Paleopathol 2018 03 23;20:98-103. Epub 2017 Aug 23.

University of Pittsburgh, Department of Anthropology, Pittsburgh, PA 15260, United States. Electronic address:

Styloid process (SP) development and its role in an individual's lived experience plays a negligible role in paleopathological research, although a handful of possible Eagle's syndrome cases have been reported. Here, the development of the stylohyoid chain and the medical research of SP variants are reviewed to inform the differential diagnosis of a probable SP fracture in a young adult male associated with the Ottoman Period (13-19thC) in Jordan. The fracture surface of the right SP is smooth rather than irregular, the coloration is uniform with the surrounding cortical bone staining, and no new bone formation is visible. Read More

J Oral Maxillofac Pathol 2017 Sep-Dec;21(3):447-453

Oral Pathologist-Private Dental Practitioner, Bengaluru, Karnataka, India.

Background: In recent years, the techniques used to identify human remains post accidents, trauma or in case of criminal investigation have been expanded, improved and rendered more complex by the emergence of technologies based on deoxyribonucleic acid (DNA) analysis. In the head and neck area, tooth has been proven to be the best quantitative source for DNA but in certain cases where the mandible specimen is edentulous or the tooth is extensively destroyed with caries, large dental restorations, mobile, or if they show any perimortem or postmortem fractures, sampling of such tooth specimen is usually avoided. In such situations, bone is considered the next best site for DNA analysis. Read More

Anthropol Anz 2018 Feb 10;75(1):49-66. Epub 2018 Jan 10.

Department of Archaeology, University of Durham South Road, Durham, DH13LE.

Abstract: The site of Tepe Hissar (Iran) experienced widespread cultural and economic changes during the Chalcolithic and Bronze Ages (5 to the 2 millennium B.C.). Read More

Am J Phys Anthropol 2018 05 4;166(1):70-83. Epub 2018 Jan 4.

Historical Sciences Department, University of Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, 35003, Spain.

Objectives: This paper addresses the prevalence and pattern of physical violence in the prehispanic society of Gran Canaria and discusses its link with the social structure and insular context in which that people lived.

Materials And Methods: 347 prehispanic crania from Guayadeque Ravine (575-1415 AD) have been examined in order to determine the frequency, types, location, and timing of trauma.

Results: Craniofacial injuries are present in 27. Read More

Am J Obstet Gynecol 2018 Jul 2;219(1):52-61. Epub 2018 Jan 2.

Southern Colorado Maternal Fetal Medicine, Colorado Springs, CO.

While global maternal mortality has decreased in the last 25 years, the maternal mortality ratio in the United States has actually increased. Maternal mortality is a complex phenomenon involving multifaceted socioeconomic and clinical parameters including inequalities in access to health care, racial and ethnic disparities, maternal comorbidities, and epidemiologic ascertainment bias. Escalating maternal mortality underscores the importance of clinician preparedness to respond to maternal cardiac arrest that may occur in any maternal health care setting. Read More

J Zoo Wildl Med 2017 Dec;48(4):1210-1214

The causes of free-living chelonian mortality events are often unknown because of infrequent recovery of remains and rapid postmortem decomposition. This study describes a technique to harvest bone marrow and detect frog virus 3-like ranavirus (FV3) using quantitative polymerase chain reaction in skeletonized eastern box turtles ( Terrapene carolina carolina) ( N = 87), and assesses agreement with concurrent perimortem samples ( N = 14). FV3 was detected in bone marrow samples from 12 turtle shells (14%). Read More

World J Emerg Med 2018 ;9(1):70-72

Accident and Emergency Department, Tseung Kwan O Hospital, Hong Kong, China.

J Forensic Dent Sci 2017 May-Aug;9(2):51-55

Department of Dental, BKN Hospital, Rohtak, Haryana, India.

Forensic odontology is the branch of dentistry which deals with the proper handling, examination, evaluation and presentation of dental findings in the interest of justice. After major disasters and perimortem assaults such as earthquakes, fires, severe head and neck trauma or gross decomposition, accurate and early identification of dead and injured becomes important. In the absence of other records in such cases, identification is based on restorations, missing teeth and prosthetic devices such as partial and complete removable/fixed prosthesis or implant retained devices. Read More

Semin Perinatol 2018 02 13;42(1):33-38. Epub 2017 Dec 13.

Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd, Bethesda, MD 20814. Electronic address:

Cardiac arrest in pregnancy is a rare and frightening event. Although not every obstetrician will encounter cardiac arrest in pregnancy during their career, it is imperative to be prepared to manage this acute emergency. The management is particularly complex due to maternal physiologic changes from pregnancy and the simultaneous management of two patients, the mother and fetus. Read More

J Matern Fetal Neonatal Med 2017 Nov 22:1-5. Epub 2017 Nov 22.

a Department of Anesthesia, and Sackler Faculty of Medicine , Rabin Medical Center, Beilinson Hospital, Petach Tikvah Israel, Tel Aviv University , Tel Aviv , Israel.

Introduction: Amniotic fluid embolism (AFE) is a rare and potentially lethal obstetric complication, commonly occurring during labor, delivery, or immediately postpartum. There is a paucity of data regarding incidence, risk factors, and clinical management. Our primary objective in this study was to evaluate clinical presentation of AFE and delineate anesthesia management of these cases. Read More

Acute Med Surg 2017 10 17;4(4):467-471. Epub 2017 Aug 17.

Rinku General Medical Center Senshu Trauma and Critical Care Center Izumisano Osaka Japan.

Cases: Perimortem cesarean delivery (PMCD) is the only way to resuscitate pregnant women in cardiac arrest, and has been found to increase maternal resuscitation rate by increasing circulating plasma volume. However, many obstetricians have not experienced a case of PMCD, as situations requiring it are rare. We report our strategy for cases of maternal cardiac arrest, on the basis of a review of published work, and present two case reports from our medical center. Read More

Isr Med Assoc J 2017 09;19(9):586-589

Department of Jewish History, Ben-Gurion University of the Negev, Beer Sheva, Israel.

Background: Maternal cardiac arrest during gestation constitutes a devastating event. Training and anticipant preparedness for prompt action in such cases may save the lives of both the woman and her fetus.

Objectives: To address a previous Jewish guideline that a woman in advanced pregnancy should not undergo any medical procedure to save the fetus until her condition is stabilized. Read More

Int J Paleopathol 2017 09 9;18:63-68. Epub 2017 Jun 9.

Laboratory of Forensic Anthropology, Department of Life Sciences/Center of Functional Ecology, University of Coimbra, Coimbra, Portugal.

Peri-mortem limb amputations are rarely reported in the paleopathological literature. The cases reported here concern severing of both hands and feet observed in three adult male skeletons, exhumed from the medieval Portuguese necropolis of Rossio do Marquês de Pombal, Estremoz, Portugal. The fact that they were found in the same site, in graves placed side by side, that all are young males, and that the three skeletons show similar perimortem injuries, make this a unique case meriting detailed analysis. Read More

Scand J Trauma Resusc Emerg Med 2017 Jul 3;25(1):62. Epub 2017 Jul 3.

Division of Perioperative Services, Intensive Care Medicine and Pain Management and Department of Anaesthesiology and Intensive Care, University of Turku and Turku University Hospital, Turku, Finland.

Background: During maternal cardiac arrest, emergency hysterotomy (EH) is recommended after four minutes of resuscitation, if no signs of spontaneous circulation are detected. This extreme procedure is believed to be potentially beneficial for both the mother and the infant. Both maternal and neonatal survivals seem to be associated to the time delay between the cardiac arrest and the delivery and in-hospital resuscitation location. Read More

Forensic Sci Med Pathol 2017 Sep 15;13(3):379-382. Epub 2017 Jun 15.

Forensic Anthropology Unit, Institut de Medicina Legal i Ciènces Forenses de Catalunya (IMLCFC), Ciutat de la Justícia, Gran Via de les Corts Catalanes, 111 Edifici G, 08075, Barcelona, Spain.

During the investigation of fresh bone fractures, it might be difficult to visualize all the fracture lines that could contribute to the interpretation of the biomechanics behind a fracture. To optimize the examination of the fracture, the bones should first be defleshed to expose the osseous surface. To reveal small fracture lines more clearly, we developed two easy, fast, cheap and non-destructive methods to enhance fracture lines and bone defects by coloring the fracture lines with ink. Read More

J Forensic Leg Med 2017 Jul 26;49:59-75. Epub 2017 May 26.

Laboratory of Morphology and Forensic Anthropology, Department of Anthropology, Faculty of Science, Masaryk University, Kotlářská 2, 611 37 Brno, Czech Republic. Electronic address:

While assessing skeletal injuries in human skeletal remains, forensic anthropologists are frequently presented with fractured, fragmented, or otherwise modified skeletal remains. The examination of evidence and the mechanisms of skeletal injuries often require that separate osseous elements be permanently or temporarily reassembled or reconstructed. If not dealt with properly, such reconstructions may impede accurate interpretation of the evidence. Read More

Fetal Diagn Ther 2017 2;42(3):232-235. Epub 2017 Jun 2.

KU Center for Advanced Fetal Care, Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Kansas School of Medicine, Kansas City, KS, USA.

Twin-twin transfusion syndrome is a complication of monochorionic-diamniotic placentation. Should one twin die, ≈30% of co-twins will also die, and if they survive, ≈30% experience severe morbidity rates, each believed secondary to hemorrhage of the co-twin into the deceased twin. We report apparently the first ultrasound-documented case of perimortem hemorrhage in twin-twin transfusion syndrome and its treatment by emergent ultrasound-guided percutaneous cord occlusion followed by percutaneous fetal intravascular transfusion. Read More

Anthropol Anz 2017 Jul 30;74(2):131-141. Epub 2017 May 30.

Institute for Anthropological Research, Ljudevita Gaja 32, Zagreb, Croatia.

Abstract: During archaeological rescue excavations carried out in 2007 at Potočani in continental Croatia, a pit containing numerous human skeletal remains (MNI = 41) was discovered. The remains were mostly articulated but also commingled and showed no clear pattern of organization. There were no associated artifacts, just a few pottery fragments probably belonging to the Copper Age Lasinja Culture (c. Read More

Exp Hematol 2017 08 26;52:40-49. Epub 2017 May 26.

Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.

Impaired immune reconstitution after hematopoietic stem cell transplantation (HSCT) is attributed in part to impaired thymopoiesis. Recent data suggest that precursor input may be a point of regulation for the thymus. We hypothesized that administration of FLT3 ligand (FLT3L) would enhance thymopoiesis after adoptive transfer of aged, FLT3L-treated bone marrow (BM) to aged, Lupron-treated hosts by increasing murine HSC (LinSca1c-Kit [LSK] cells) trafficking and survival. Read More

Int J Paleopathol 2017 06 12;17:10-17. Epub 2017 Mar 12.

CIAS (Research Centre for Anthropology and Health), Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal.

Differentiating between medical procedures performed antemortem, perimortem or postmortem in skeletal remains can be a major challenge. This work aims to present evidence of procedures to treat rhinosinusitis (RS) and mastoiditis, suggest criteria for the diagnosis of frontal sinus disease, and frame the individuals described in their medical historical context. In the International Exchange collection, the skull (878) of a 24-year-old male, who died in 1933 due to frontal sinusitis and meningitis, presents evidence of a trepanation above the right frontonasal suture, and micro/macroporosity on the superciliary arches. Read More

J Obstet Gynaecol India 2017 Apr 13;67(2):143-146. Epub 2016 Aug 13.

Department of Obstetrics and Gynaecology, Bankura Sammilani Medical College and Hospital (BSMCH), Gobindanagar, Bankura, India.

Emerg Med J 2017 May 7;34(5):326-330. Epub 2017 Mar 7.

Academic Department of Clinical Traumatology, Queen Elizabeth Hospital Birmingham, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.

The need for prehospital resuscitative hysterotomy/perimortem caesarean section is rare. The procedures can be daunting and clinically challenging for practitioners. Maternal death can be averted by swift and decisive action. Read More

BJOG 2017 Aug 24;124(9):1374-1381. Epub 2017 Feb 24.

University Hospitals of Leicester NHS Trust, Leicester, UK.

Objective: To describe the incidence, risks, management and outcomes of cardiac arrest in pregnancy in the UK population, with specific focus on the use of perimortem caesarean section (PMCS).

Design: A prospective, descriptive study using the UK Obstetric Surveillance System (UKOSS).

Setting: All UK hospitals with maternity units. Read More

Int J Legal Med 2017 Nov 23;131(6):1707-1718. Epub 2017 Feb 23.

Institute of Legal Medicine, University of Bonn, Bonn, Germany.

The expression of heat shock proteins (hsps) increases in cases of hyperthermal cellular stress in order to protect cellular structures. Hsps can be visualized with immunohistochemical staining. We examined 48 cases of death from fire and excessive heat and a control group of 100 deaths without any perimortem thermal stress, measuring both the hsp27 and hsp70 expressions in myocardial, pulmonary, and renal tissues. Read More