497 results match your criteria Perilymph Fistula

Perilymph Fistula as a Complication of Eustachian Tube Dilation and Tympanoplasty.

Case Rep Otolaryngol 2022 7;2022:5978757. Epub 2022 May 7.

Faculty of Medicine OWL, Bielefeld University, Campus Mitte, Department of Otolaryngology, Head and Neck Surgery, Bielefeld, Germany.

Eustachian tube dilation (ETD) is an established, minimally invasive therapeutic approach for chronic eustachian tube dysfunction. The complications associated with performing a ETD are rare. A 22-year-old female patient presented with chronic otitis media on the right side and chronic obstructive tube dilation disorder on both sides. Read More

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Post-concussive Dizziness: A Review and Clinical Approach to the Patient.

Gerard J Gianoli

Front Neurol 2021 4;12:718318. Epub 2022 Jan 4.

The Ear and Balance Institute, Covington, LA, United States.

Dizziness is a frequent complaint after head trauma. Among patients who suffer a concussion (mild traumatic brain injury or mTBI), dizziness is second only to headache in symptom frequency. The differential diagnosis of post-concussive dizziness (PCD) can be divided into non-vestibular, central vestibular and peripheral vestibular causes with growing recognition that patients frequently exhibit both central and peripheral findings on vestibular testing. Read More

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January 2022

The Relationship Between the Third Window Abnormalities and Inner Ear Malformations in Children with Hearing Loss.

J Int Adv Otol 2021 Sep;17(5):387-392

Department of Otorhinolaryngology, Dokuz Eylül University School of Medicine, İzmir, Turkey.

Objective: To evaluate the relationship between the third window abnormalities and congenital inner ear malformations in pediatric patients with different types of hearing loss. If such a relationship should exist, it would be important to take it into account, in order to diagnose and treat pediatric hearing loss cases more accurately.

Methods: Two hundred twenty-one children with hearing loss who had temporal bone computed tomography (CT) examination and were identified from 2013 to 2018 were retrospectively evaluated. Read More

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September 2021

[Peculiarities of differential diagnostics of perilymphatic fistulas of the labyrinth windows of non-inflammatory genesis].

Vestn Otorinolaringol 2021 ;86(4):17-22

Moscow Regional Scientific Research Clinical Institute MF Vladimirsky, Moscow, Russia.

The Purpose Of The Study: To determine the value of the results of various audiological and vestibulometric studies for the differential diagnosis of non-inflammatory perilymphatic fistulas of the labyrinth windows (PFOLW).

Material And Methods: The retrospective and prospective analysis of the informative value of the results of audiological and vestibulometric studies was carried out in 124 people with different combinations of cochleovestibular complaints, who had different pathology of the inner and middle ear, with different terms of the disease - from several days to 30 years. To assess the informativeness of the applied testing, the following operational characteristics were determined: general sensitivity (Se), specificity (Sp) and the prognostic value of a positive result (PPV=positive predictive value). Read More

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September 2021

Editorial: Third Window Syndrome.

Front Neurol 2021 18;12:704095. Epub 2021 Jun 18.

Departments of Otolaryngology, Neurobiology, Communication Science & Disorders, Bioengineering and Mechanical Engineering and Materials Science, University of Pittsburgh, Pittsburgh, PA, United States.

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Intratympanic Steroid Injection Complicated by Iatrogenic Perilymphatic Fistula: A Cautionary Tale.

Laryngoscope 2021 09 11;131(9):2088-2090. Epub 2021 May 11.

Department of Otolaryngology - Head and Neck Surgery, University of Washington, Seattle, Washington, U.S.A.

Intratympanic (IT) steroid therapy is a mainstay treatment for sudden sensorineural hearing loss (SSNHL) for both initial therapy and salvage therapy. We report a rare case of iatrogenic perilymphatic fistula that resulted from trauma during an IT steroid injection for SSNHL. We discuss the diagnosis and treatment in the current case and compare it with previous reports from the literature. Read More

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September 2021

Endoscopic Repair of Traumatic Perilymphatic Fistula in Children: A Case Series.

J Int Adv Otol 2021 Mar;17(2):182-185

Department of Otolaryngology, Harvard Medical School, Boston, MA, USA;Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, MA, USA.

Traumatic perilymphatic fistula (PLF) is an uncommon cause of acute vestibular symptoms and hearing loss following head injury in children. We describe the management of 3 pediatric patients with traumatic PLF using an endoscopic ear surgery (EES) approach. Three pediatric patients with traumatic PLF underwent repair via an EES approach between August and October 2018. Read More

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[Traumatic perilymphatic fistula. Report of a pediatric case].

Arch Argent Pediatr 2021 04;119(2):e167-e170

División de Otorrinolaringología, Hospital General de Niños Pedro De Elizalde. Buenos Aires, Argentina.

Traumatic perilymphatic fistula is an unusual pathology. Generally caused by pencils, swabs, hair buckles, and matches. Among the most frequent symptoms, patients can present hearing loss and vertigo. Read More

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Significance of Pseudo-Conductive Hearing Loss and Positional Nystagmus for Perilymphatic Fistula: Are They Related to Third-Window Effects?

Clin Exp Otorhinolaryngol 2021 Aug 26;14(3):268-277. Epub 2021 Feb 26.

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Objectives: Patients' clinical presentation is critical for identifying suspected perilymphatic fistula (PLF). The involvement of third-window lesions in the pathomechanism of PLF has been hypothesized. This study investigated the clinical features of PLF and the relationship of the third-window effect with PLF. Read More

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A case of perilymphatic fistula caused by surgical drilling with preserved normal hearing.

Am J Otolaryngol 2021 Mar-Apr;42(2):102753. Epub 2020 Oct 17.

Department of Otolaryngology, Juntendo University Nerima Hospital, Tokyo, Japan; Department of Otolaryngology, Juntendo University, Tokyo, Japan; Department of Neurotology, Mejiro University, Saitama, Japan.

We introduce our horrible experience of lateral semicircular canal exposure due to unintended drilling during left facial nerve decompression. Nearly half of the canal was drilled-out, however, the membranous labyrinth was preserved and the defect was covered with temporal fascia. Immediately after surgery, the patient complained of vertigo with right beating nystagmus. Read More

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September 2021

Congenital Membranous Stapes Footplate Producing Episodic Pressure-Induced Perilymphatic Fistula Symptoms.

Front Neurol 2020 10;11:585747. Epub 2020 Nov 10.

Department of Otorhinolaryngology, Saitama Medical University, Saitama, Japan.

Recent third window syndrome studies have revealed that the intact bony labyrinth and differences in the stiffness of the oval and round windows are essential for proper cochlear and vestibular function. Herein we report a patient with a congenital dehiscence of the right stapes footplate. This dehiscence caused long-standing episodic pressure-induced vertigo (Hennebert sign). Read More

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November 2020

Traumatic Stapediovestibular Dislocation With Intact Stapes: Report and Review.

Ear Nose Throat J 2020 Oct 23:145561320968925. Epub 2020 Oct 23.

Department of Otolaryngology-Head and Neck Surgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

Stapediovestibular dislocation is a rare disorder as a result of traumatic injury to the structures in the middle ear. We described a case of a 60-year-old female with stapediovestibular dislocation with associated perilymph fistula. She presented with symptoms including hearing loss, vertigo, and tinnitus after a penetrating injury by an ear pick. Read More

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October 2020

Perilymphatic Fistula: A Review of Classification, Etiology, Diagnosis, and Treatment.

Front Neurol 2020 15;11:1046. Epub 2020 Sep 15.

Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, CA, United States.

A perilymphatic fistula (PLF) is an abnormal communication between the perilymph-filled inner ear and the middle ear cavity, mastoid, or intracranial cavity. A PLF most commonly forms when the integrity of the oval or round window is compromised, and it may be trauma-induced or may occur with no known cause (idiopathic). Controversy regarding the diagnosis of idiopathic PLF has persisted for decades, and the presenting symptoms may be vague. Read More

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September 2020

[The diagnostic value of cochlin-tomoprotein in perilymphatic fistula].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2020 Sep;34(9):857-861

Perilymphatic fistula(PLF) is defined as an abnormal communication between the fluid(perilymph) -filled space of the inner ear and the air-filled space of the middle ear and mastoid, or cranial spaces. At present the diagnostic criteria for perilymphatic fistula is the fistula hole confirmed by the microscope and endoscope between the middle ear and inner ear, the hole is located in the round or oval window, fractured bony labyrinth, microfissures, anomalous footplate, and can occur after head trauma or barotrauma, chronic inflammation, or in otic capsule dehiscence. Recently, the cochlin-tomoprotein(CTP) detected from the middle ear. Read More

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September 2020

Membranous or Hypermobile Stapes Footplate: A New Anatomic Site Resulting in Third Window Syndrome.

Front Neurol 2020 20;11:871. Epub 2020 Aug 20.

Clinical Audiologist, Department of Otolaryngology-Head and Neck Surgery and Communication Sciences, University of Louisville, Louisville, KY, United States.

To describe a potentially underappreciated pathology for post-traumatic persistent intractable dizziness and third window syndrome as well as the methods to diagnose and surgically manage this disorder. Observational analytic case studies review at a tertiary care medical center. Patients suffering persistent dizziness following head trauma and demonstrating Tullio phenomena or Hennebert signs are included. Read More

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Perilymphatic Fistula: Consideration Based on MRI and Surgery.

Otol Neurotol 2021 Jan;42(1):e107-e109

Department of Head and Neck Surgery, Lariboisière University Hospital, Paris, France.

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January 2021

Trauma-induced vestibular dysfunction: Possible functional repair under α1-antitrypsin-rich conditions.

Cell Immunol 2020 10 12;356:104150. Epub 2020 Jun 12.

Department of Clinical Biochemistry & Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Transient vestibular organ deafferentation, such that is caused by traumatic tissue injury, is presently addressed by corticosteroid therapy. However, restoration of neurophysiological properties is rarely achieved. Here, it was hypothesized that the tissue-protective attributes of α1-antityrpsin (AAT) may promote restoration of neuronal function. Read More

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October 2020

Prevalence of occult cochlear basal turn patency.

Acta Otolaryngol 2020 Nov 17;140(11):889-892. Epub 2020 Aug 17.

Department of Otolaryngology, University of Florida, Gainesville, FL, USA.

Background: Perilymph gusher (PLG) is a rare complication of otologic surgery attributed to a communication between the cochlea and the internal auditory canal (IAC). Subtle patency between the cochlear basal turn and IAC has recently been identified on computed tomography (CT) as a risk factor, specifically when the defect is > 0.75 mm. Read More

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November 2020

Imaging Analysis for Cholesteatoma Extension to the Perilymphatic Space in Labyrinth Fistulae.

Laryngoscope 2021 04 17;131(4):E1301-E1307. Epub 2020 Aug 17.

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Objectives/hypothesis: Disturbed perilymph behind a labyrinth fistula can lead to hearing deterioration; thus, delicate manipulation is required during surgery for cholesteatomatous fistulae with matrix extension to the perilymphatic space (EPS). However, it remains challenging to identify the EPS preoperatively. This study aimed to evaluate the diagnostic value of computed tomography (CT) for preoperative prediction of the EPS of cholesteatomatous fistulae. Read More

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[Does sealing the oval window in addition to the round window bring an advantage in reserve therapy of acute idiopathic deafness?]

HNO 2021 Jan;69(1):31-41

Klinik für Hals‑, Nasen- und Ohrenheilkunde, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Deutschland.

Background: Following sudden unilateral deafness or severe sensorineural hearing loss, patients with unsuccessful intravenous steroid therapy can be treated with explorative tympanotomy with sealing of the round (RW) and/or oval window (OW), due to suspected rupture of the RW with perilymph fistula (PLF) or a fissula ante fenestram (FAF). This study investigated whether additional sealing of the oval window (RW+OW) achieved an improved hearing benefit as compared to sealing of the round window only (RW) .

Methods: This retrospective study investigated 54 patients with acute profound hearing loss who underwent tympanoscopy. Read More

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January 2021

Oval window perilymph fistula in child with recurrent meningitis and unilateral hearing loss.

BMJ Case Rep 2020 Jul 26;13(7). Epub 2020 Jul 26.

Department of Paediatric Otolaryngology, Cochlear Implants, Great Ormond Street Hospital for Children NHS Trust, London, UK.

A 2-year-old boy presented to Ears, Nose and Throat (ENT) surgeons with unilateral hearing loss. Following a prodrome of upper respiratory tract infection (URTI), he developed two episodes of pneumococcal meningitis in quick succession. This case demonstrates an unusual cause of perilymph fistula diagnosed on imaging and confirmed surgically. Read More

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Exploratory tympanotomy in sudden sensorineural hearing loss for the identification of a perilymphatic fistula - retrospective analysis and review of the literature.

J Laryngol Otol 2020 Jun;134(6):501-508

Department of Otolaryngology, Hannover Medical School, Hannover, Germany.

Objective: The diagnostic value of exploratory tympanotomy in sudden sensorineural hearing loss remains controversial. This study and review were performed to identify the incidence of perilymphatic fistula in patients with sudden sensorineural hearing loss. The effectiveness of tympanotomy for sealing of the cochlear windows in cases with perilymphatic fistula was evaluated. Read More

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Use of topical fluorescein in the diagnosis and localization of perilymphatic fistula.

Am J Otolaryngol 2020 Sep - Oct;41(5):102488. Epub 2020 Apr 11.

Bezmialem Vakif University, Faculty of Medicine, Department of Otorhinolaryngology, Fatih, Istanbul, Turkey.

Objective: The purpose of this video presentation is to demonstrate the effect of intraoperative dilute topical fluorescein in perilympatic fistula diagnosis and localization.

Materials And Methods: Explorative tympanotomy was performed for the diagnosis, localization and repair of the fistula in the patient who had a pre-diagnosis of perilymphatic fistula. Topical fluorescein was applied intraoperatively to localize the defect. Read More

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November 2020

Vestibular drop attack: A potential origin from perilymphatic fistula?

Med Hypotheses 2020 Mar 6;140:109668. Epub 2020 Mar 6.

Organi di Senso Department University, Sapienza University of Rome, Viale del Policlinico, 151, 00161 Rome, Italy. Electronic address:

Vestibular drop attacks are defined as a sudden fall to the ground without an obvious loss of consciousness lasting a few minutes or seconds. They are usually associated with Meniere's Disease during Tumarkin's phase. This hypothesis was produced in consideration of the case of a young girl affected by perilymphatic fistula and her Drop attacks. Read More

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CT and MRI for the diagnosis of perilymphatic fistula: a study of 17 surgically confirmed patients.

Eur Arch Otorhinolaryngol 2020 Apr 10;277(4):1045-1051. Epub 2020 Feb 10.

Service de Radiologie 1, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.

Background: We evaluated the usefulness of CT and MRI for the diagnosis of perilymphatic fistula (PLF) of the round (RW) and/or oval (OW) windows, with surgery as gold standard.

Methods: We retrospectively enrolled 17 patients who presented a surgically confirmed PLF of the round (RW) or oval (OW) windows. All patients were imaged by CT + MRI (T2W SSFP without contrast) prior to surgery (= gold standard). Read More

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Third Window Syndrome: Surgical Management of Cochlea-Facial Nerve Dehiscence.

Front Neurol 2019 13;10:1281. Epub 2019 Dec 13.

Department of Neurosurgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States.

This communication is the first assessment of outcomes after surgical repair of cochlea-facial nerve dehiscence (CFD) in a series of patients. Pre- and post-operative quantitative measurement of validated survey instruments, symptoms, diagnostic findings and anonymous video descriptions of symptoms in a cohort of 16 patients with CFD and third window syndrome (TWS) symptoms were systematically studied. Observational analytic case-control study. Read More

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December 2019

Total endoscopic stapes surgery: Systematic review and pooled analysis of audiological outcomes.

Laryngoscope 2020 05 30;130(5):1282-1286. Epub 2019 Sep 30.

Department of Otolaryngology, St. George's Hospital, London, United Kingdom.

Objective: This study evaluates the current evidence base for total endoscopic stapes surgery, specifically to establish current efficacy and safety of the technique within clinical practice.

Data Sources: A systematic review of the literature on endoscopic stapes surgery was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis checklist. A comprehensive search of PubMed, Embase, and the Cochrane Central Register of Controlled Trials database for relevant publications for all available dates with appropriate Medical Subject Headings search criteria in January 2018. Read More

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Perilymphatic Fistulas and Superior Semi-Circular Canal Dehiscence Syndrome.

Adv Otorhinolaryngol 2019 15;82:93-100. Epub 2019 Jan 15.

Perilymphatic fistulas (PLF) and superior semi-circular canal dehiscence syndrome (SCDS) are 2 conditions that can present with sound and/or pressure-induced vertigo. PLF should be suspected in cases of trauma or surgery, while a spontaneous PLF is a diagnosis of exclusion. Research is ongoing to identify an ideal biomarker for perilymph. Read More

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December 2019

Surgical Outcomes on Hearing and Vestibular Symptoms in Barotraumatic Perilymphatic Fistula.

Otol Neurotol 2019 04;40(4):e356-e363

Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul.

Objective: To analyze surgical results on hearing and vestibular symptoms in patients with barotraumatic perilymphatic fistula (PLF) according to diagnostic criteria.

Methods: A total of 39 patients (41 ears) who underwent surgery on suspicion of barotraumatic PLF from January 2005 to December 2017 were included. Pure tone audiometry and videonystagmography (VNG) recording for spontaneous nystagmus and positional tests were performed preoperatively and postoperatively at 1 week and 1 month. Read More

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