96 results match your criteria Perifolliculitis Capitis Abscedens et Suffodiens


A case of hidradenitis suppurativa with perifolliculitis capitis abscedens et suffodiens successfully treated with a human anti- tumor necrosis factor monoclonal antibody.

Clin Exp Dermatol 2021 Jun 7. Epub 2021 Jun 7.

Department of Dermatology, Hirosaki University Graduate School of Medicine, Aomori, Japan.

Hidradenitis suppurativa (HS) is a chronic autoinflammatory skin disorder characterized by recurrent painful nodules, abscesses, sinus tracts, and scarring on intertriginous body areas. Perifolliculitis capitis abscedens et suffodiens (PCAS) is a component of the follicular occlusion tetrad along with HS, acne conglobata, and pilonidal cyst. We report a case of HS with PCAS that was successfully treated with adalimumab, a human anti-tumor necrosis factor (TNF) monoclonal antibody. Read More

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Recalcitrant Dissecting Cellulitis of the Scalp Treated Successfully with Adalimumab with Hair Regrowth: A Case Report.

Clin Cosmet Investig Dermatol 2021 10;14:455-458. Epub 2021 May 10.

Department of Pathology, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.

Dissecting cellulitis (DC) of the scalp or perifolliculitis capitis abscedens et suffodiens is a rare chronic inflammatory condition of the scalp manifested by perifollicular pustules, nodules, abscesses and sinuses that result into scarring alopecia. Treatment of DC is challenging and often disappointing. We report a 38-year-old male patient with DC for 5 years, and multiple topical and systemic therapies had shown poor effect. Read More

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Dissecting cellulitis of the scalp treated by tumour necrosis factor inhibitors: a case series.

Eur J Dermatol 2021 Feb;31(1):81-85

Dpt of Dermatology and Inserm Unit 1098 RIGHT, University of Franche Comté and University Hospital, Besançon, France.

Background: Dissecting cellulitis of the scalp (DCS), also known as Hoffmann disease or perifolliculitis capitis abscedens et suffodiens, is a rare disease characterized by chronic inflammation of the scalp. Treatment is difficult and often disappointing.

Objectives: To report our experience of TNF inhibitors in a series of patients with DCS. Read More

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February 2021

The role of biologic treatment in special scenarios in hidradenitis suppurativa: Facial and nape phenotype, dissecting cellulitis of the scalp, and lymphedema.

Dermatol Ther 2021 03 15;34(2):e14829. Epub 2021 Feb 15.

Hidradenitis Suppurativa Clinic, Department of Dermatology, Hospital Universitario Virgen de las Nieves, Granada, Spain.

Hidradenitis suppurativa (HS) is a chronic inflammatory disorder affecting the hair follicle which typically affects the axilla, inguinal, submammary, and perianal areas. Atypical HS, such as facial HS, dissecting cellulitis of the scalp (DCS), nape HS, and HS lymphedema has also been described. There is scarce evidence about the treatment of atypical HS. Read More

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Photodynamic therapy pre-treated by fire needle combined with isotretinoin in the treatment of refractory perifolliculitis capitis abscedens et suffodiens: Case report.

Photodiagnosis Photodyn Ther 2021 Mar 20;33:102103. Epub 2020 Dec 20.

Department of Dermato-venereology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China. Electronic address:

Perifolliculitis capitis abscedens et suffodiens (PCAS) is a rare chronic inflammatory dermatosis of the scalp, which is a refractory and recrudescent disease. Symptoms of PCAS include follicular papules, suppurative nodules, cysts, sinuses, fistulas, and these usually evolve into patchy alopecia or cicatricial alopecia, which seriously affects the beauty and quality of life of patients. In this paper, we report 3 cases of PCAS each of whom received 5% 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT) combined with isotretinoin. Read More

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A new familial presentation of dissecting cellulitis: The genetic implications on scarring alopecias.

JAAD Case Rep 2020 Aug 1;6(8):705-707. Epub 2020 Jun 1.

Department of Dermatology, Dermika Centro Dermatológico Láser, Guadalajara, Mexico.

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Photodynamic therapy combined with dermatosurgical approach for Perifolliculitis Capitis Abscedens et Suffodiens.

Photodiagnosis Photodyn Ther 2020 Jun 17;30:101767. Epub 2020 Apr 17.

Department of Medical Cosmetology, Department of Dermatology, Affiliated Hospital of Nantong University, Nantong 226001, China. Electronic address:

Perifolliculitis capitis abscedens et suffodiens (PCAS) is a rare, chronic, suppurative and inflammatory scalp disease with aetiology and pathogenesis not completely understood. The treatment of PCAS usually represents a challenging problem with frustrating outcome (1). Photodynamic therapy (PDT) is an approach considered to be useful to treat tumors, bacterial and fungal infections (2-4). Read More

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Surgical interventions combined with photodynamic therapy in the treatment of Perifolliculitis Capitis Abscendens et Suffodiens: Report of 5 cases.

Photodiagnosis Photodyn Ther 2020 Jun 25;30:101660. Epub 2020 Feb 25.

Department of Dermatology, Xiangya Hospital of Central South University, Changsha 410005, China. Electronic address:

Perifolliculitis capitis abscedens et suffodiens (PCAS), also known as dissecting cellulitis of the scalp (DCS), is a rare, chronic, suppurative inflammatory disease of the scalp which may evolve into cicatricial alopecia. Its refractory nature has a detrimental impact on patients' quality of life. Here, we report five cases of PCAS treated with 5% 5-aminolevulinic acid-based photodynamic therapy (ALA-PDT), prior to which different methods of surgical intervention were given. Read More

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A Case Report of Tumor Necrosis Factor Alpha Inhibitors in an Active Duty Service Member with Dissecting Cellulitis of the Scalp Resistant to Treatment.

Mil Med 2020 08;185(7-8):e1309-e1311

Department of Dermatology, San Antonio Military Health System Laser Surgery and Scar Center, 2200 Bergquist Drive, San Antonio, TX 78236.

Dissecting cellulitis of the scalp represents a disease of follicular occlusion that may be worsened by tight-fitting clothing, such as the patrol cap or advanced combat helmet used by military service members. Treatment poses a challenge to the clinician, and the treatment of choice, oral retinoids, may not improve the condition sufficiently to maintain active duty status. Early treatment augmentation with tumor necrosis factor-alpha inhibitors may improve efficacy of oral retinoids and prevent medical separation of the active duty service member. Read More

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Trichoscopy findings in dissecting cellulitis.

An Bras Dermatol 2019 Sep - Oct;94(5):608-611. Epub 2019 Sep 30.

Alopecia Outpatient Clinic, Hospital Naval Marcílio Dias, Rio de Janeiro, RJ, Brazil.

Dissecting cellulitis is an inflammatory, chronic, and recurrent disease of the hair follicles that mainly affects young Afro-descendent men. Trichoscopy is a method of great diagnostic value for disorders of the scalp. Clinical and trichoscopic findings of dissecting cellulitis are heterogeneous and may present features common to non-cicatricial and scarring alopecia. Read More

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December 2019

Staged Full-Thickness Excisions and Porcine Xenograft Placement for Extensive Dissecting Cellulitis of the Scalp.

Authors:
Rajiv I Nijhawan

Dermatol Surg 2019 10;45(10):1324-1327

Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.

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October 2019

Follicular occlusion tetrad in a male patient with pachyonychia congenita: clinical and genetic analysis.

J Eur Acad Dermatol Venereol 2019 Oct;33 Suppl 6:36-39

Dermatology Clinic, University of Catania, Catania, Italy.

The case of a 24-year-old male patient affected by follicular occlusion tetrad (acne conglobata, hidradenitis suppurativa, pilonidal cyst and dissecting cellulitis of the scalp) associated with clinical signs of pachyonychia congenita (PC)-2 (focal palmoplantar keratoderma, plantar pain, onycodystrophy and multiple cysts) is reported. The diagnosis was supported by genetic analysis that showed heterozygous mutation within the exon 1 of KRT17 gene. This case may reflect different expressions of a phenotypic spectrum induced by a common genetic alteration. Read More

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October 2019

Approach to treatment of refractory dissecting cellulitis of the scalp: a systematic review.

J Dermatolog Treat 2021 Mar 9;32(2):144-149. Epub 2019 Aug 9.

Department of Dermatology, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Background: Dissecting cellulitis is a chronic inflammatory dermatosis that results in disfiguring and painful, purulent lesions. Treatment of patients with disease resistant to standard therapies, including intralesional or topical steroids or antibiotics, can be a dilemma for clinicians.

Methods: We performed a systematic review of the literature in November 2018 to find articles which presented treatment options and outcomes of patients who failed prior treatment with standard therapies. Read More

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Perifolliculitis capitis abscedens et suffodiens treatment with tumor necrosis factor inhibitors: A case report and review of published cases.

J Dermatol 2019 Sep 4;46(9):802-807. Epub 2019 Jul 4.

Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.

Perifolliculitis capitis abscedens et suffodiens (PCAS) or dissecting cellulitis is a rare condition presenting deep follicular occlusions, follicular ruptures and follicular infections in the scalp area with unknown etiology, which consequently cause primary neutrophilic cicatricial alopecia by the repeated follicular inflammation. PCAS is categorized as one of the "follicular occlusion tetrad" along with hidradenitis suppurativa, acne conglobata and pilonidal cyst. In the pathogenesis of the follicular occlusion tetrad, the involvement of neutrophils and its activator tumor necrosis factor (TNF) have been discussed. Read More

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September 2019

Scrotal elephantiasis associated with follicular occlusion triad: A case report and literature review.

Medicine (Baltimore) 2019 Apr;98(16):e15263

Department of Urology, Qilu Hospital of Shandong University, Jinan, China.

Rationale: Follicular occlusion triad (FOT) is an autosomal recessive inherited disease and no more than 3 variants of the triad have been reported. We give a report in which scrotal elephantiasis is a variant of FOT and further perform a literature review.

Patient Concerns: A 41-year-old man came to us because of a large scrotal cyst and generalized skin lesions that had occurred over the past 10 years. Read More

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[Dissecting cellulitis of the scalp].

Rev Prat 2019 Jan;69(1):63

Service de dermatologie, CHU Mohamed VI d'Oujda, université Mohammed Premier, Oujda, Maroc. Laboratoire d'épidémiologie de recherche scientifique et de recherche clinique, Oujda, Maroc.

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January 2019

Perifolliculitis capitis abscedens et suffodiens successfully treated with Saireito.

Authors:
Ichiro Kurokawa

J Dermatol 2019 08 27;46(8):e299-e301. Epub 2019 Feb 27.

Department of Dermatology, Meiwa Hospital, Nishinomiya, Japan.

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Perifolliculitis Capitis Abscedens et Suffodiens Treated with Anti-tumor Necrosis Factor-alpha - Possible New Treatment Option.

Acta Dermatovenerol Croat 2018 Oct;26(3):255-289

Ines Sjerobabski Masnec, MD, Department of Dermatology and Venereology, Sestre milosrdnice University Hospital Center , Vinogradska 29, 10000 Zagreb , Croatia;

The case of a 26-year-old male patient with perifolliculitis capitis abscedens et suffodiens (PCAS) who later developed hidradenitis suppurativa (HS) and exacerbation of acne is presented. The patient did not respond well to conventional treatment including isotretinoin and oral antibiotics. Quality of life was significantly impaired. Read More

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October 2018

Perifolliculitis capitis abscedens et suffodiens: eine Fallserie mit 66 Patienten und ein Vorschlag zur Klassifikation.

J Dtsch Dermatol Ges 2018 Oct;16(10):1219-1227

Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

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October 2018

Dissecting cellulitis of the scalp successfully treated with ALA-PDT: Case report.

Photodiagnosis Photodyn Ther 2018 Dec 2;24:182-184. Epub 2018 Oct 2.

Department of Dermatology, The Second Xiangya Hospital of Central South University, Changsha, 410011, China. Electronic address:

A case of recalcitrant dissecting cellulitis of the scalp (DCS) in a 23-year-old male patient was treated with 4 times of topical ALA-PDT at intervals of 10-15 days. The patient responded well without any unbearable adverse effects and presented satisfactory effects. Before applying this therapy, the patient and his doctors had tried other methods, specifically glucocorticoids, intradermal injection, and even surgical treatment, but none of them had presented satisfactory effects. Read More

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December 2018

Dissecting folliculitis (dissecting cellulitis) of the scalp: a 66-patient case series and proposal of classification.

J Dtsch Dermatol Ges 2018 Oct 31;16(10):1219-1226. Epub 2018 Aug 31.

Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Background And Objectives: Dissecting folliculitis (DF) or dissecting cellulitis of the scalp is regarded as a rare disease with disfiguring scarring alopecia. This study aimed to analyze the features of DF and to propose a classification to define its severity.

Patients And Methods: A hospital-based retrospective study was conducted. Read More

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October 2018

Treatment of dissecting cellulitis of the scalp with 10% ALA-PDT.

Lasers Surg Med 2019 04 23;51(4):332-338. Epub 2018 Aug 23.

Department of Dermatology, The First Hospital of China Medical University, Shenyang, China.

Background: Dissecting cellulitis of the scalp (DCS) is difficult to be treated and 5-aminolaevulinic acid photodynamic therapy (ALA-PDT) is considered to be a potential treatment for inflammatory skin diseases.

Objective: To analyze the efficacy and safety of ALA-PDT on DCS.

Materials And Methods: The treatment areas of DCS patients were incubated with freshly prepared 10% ALA for 3 hours. Read More

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Yellow dots in trichoscopy: relevance, clinical significance and peculiarities.

An Bras Dermatol 2017 Sep-Oct;92(5):724-726

Alopecia Outpatient Clinic at Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil.

Yellow dots are follicular ostium filled with keratin and/or sebum. Initially, they were exclusively associated with alopecia areata. Currently they have also been described in androgenetic alopecia, chronic cutaneous (discoid) lupus erythematosus, and dissecting cellulitis. Read More

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February 2018

Image Gallery: Dissecting cellulitis of the scalp following anabolic steroid use.

Br J Dermatol 2017 10;177(4):e160

Division of Dermatology, University of Arizona, Tucson, AZ, U.S.A.

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October 2017

Heterogeneity of trichoscopy findings in dissecting cellulitis of the scalp: correlation with disease activity and duration.

Br J Dermatol 2017 12 16;177(6):e331-e332. Epub 2017 Nov 16.

Dermatology Clinic, University of Catania, Catania, Italy.

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December 2017

Regarding trichoscopy of dissecting cellulitis of the scalp.

J Am Acad Dermatol 2017 06;76(6):e213

Dermatology Clinic, University of Catania, Italy. Electronic address:

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Dissecting Cellulitis of the Scalp with Excellent Response to Isotretinoin.

Pediatr Dermatol 2017 Jul 19;34(4):e210-e211. Epub 2017 Apr 19.

Division of Dermatology, University of Kansas Medical Center, Kansas City, Kansas.

An 18-year-old man presented for evaluation of a 1-year history of painful nodules on the scalp with associated hair loss. Physical examination revealed multiple confluent, fluctuant, boggy nodules on the scalp with overlying alopecic patches. Based on these findings, a diagnosis of dissecting cellulitis of the scalp was made and the patient was successfully treated with oral isotretinoin therapy. Read More

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