Constrictive Pericarditis and Primary Amenorrhea with Syndactyly in an Iranian Female: Mulibrey Nanism Syndrome.
- Tahereh Davarpasand,
- Maryam Sotoudeh Anvari,
- Mohammad Naderan,
- Mohammad Ali Boroumand,
- Hossein Ahmadi
J Tehran Heart Cent 2016 Oct;11(4):187-191
Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.
Mulibrey nanism is a rare autosomal recessive syndrome caused by a mutation in the TRIM37 gene with severe growth retardation and multiple organ involvement. Early diagnosis is important because 50% of the patients develop congestive heart failure owing to constrictive pericarditis, and this condition plays a critical role in the final prognosis. A 37-year-old female patient presented with symptoms of dyspnea on exertion and shortness of breath. Read More