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    1 OF 59

    The role of colchicine in the treatment of autoinflammatory diseases.
    Curr Pharm Des 2018 Jan 15. Epub 2018 Jan 15.
    Department of Pathophysiology, Medical School, National and Kapodistrian University of Athens. Greece.
    Colchicine has been longstanding and widely used for the treatment of acute gout flares and prevention of gout relapses. Its use has been extended to a series of autoinflammatory diseases, such as familial Mediterranean fever and more recently to periodic fever with aphthous stomatitis, pharyngitis and adenitis, Behcet's disease and idiopathic recurrent acute pericarditis. In this review, we summarize current indications of colchicine use, discuss its pharmacokinetics and mechanism of action and examine its use in the treatment of autoinflammatory diseases. Read More

    The role of colchicine in pericardial syndromes.
    Curr Pharm Des 2018 Jan 15. Epub 2018 Jan 15.
    First Cardiology Department, Hippokration General Hospital, National and Kapodistrian University of Athens. Greece.
    Background: Colchicine is an old drug originally employed for the treatment of inflammatory disorders such as acute gout and familiar Mediterranean fever.

    Methods: In the past few decades, colchicine has been at the forefront of the pharmacotherapy of several cardiac diseases, including acute and recurrent pericarditis, coronary artery disease, prevention of atrial fibrillation and heart failure. In this review, we have summarized the current evidence based medicine and guidelines recommendations in the specific context of pericardial syndromes. Read More

    Dissecting the Diagnosis - An Unusual Case of Pericarditis.
    Acute Med 2017 ;16(4):200-203
    Acute Medicine Consultant, Huddersfield Royal Infirmary, Acre St, Lindley, Huddersfield. HD3 3EA.
    Chest pain is an extremely common presenting complaint on the acute medical unit. It is important to distinguish between patients who have serious pathology and those without. Often, the focus is on ruling out an acute coronary syndrome and inadequate consideration is given to other possible causes. Read More

    Diagnosis of Budd-Chiari syndrome.
    Abdom Radiol (NY) 2017 Dec 28. Epub 2017 Dec 28.
    Department of Radiology, Hôpital Beaujon, HUPNVS, 100, Bd du Général Leclerc, Clichy, France.
    Budd-Chiari syndrome (BCS) is defined by clinical and laboratory signs associated with partial or complete impairment of hepatic venous drainage in the absence of right heart failure or constrictive pericarditis. Primary BCS is the most frequent type and is a complication of hypercoagulable states, in particular myeloproliferative neoplasms. Secondary BCS involves tumor invasion or extrinsic compression. Read More

    Surgical revascularization of the celiac artery for persistent intestinal ischemia in short bowel syndrome.
    Int J Surg 2018 Jan 13;49:39-44. Epub 2017 Dec 13.
    Department of Gastroenterology, Inflammatory Bowel Diseases, Nutritional Support and Intestinal Transplantation, GHUPNVS, Faculté de Médecine Denis Diderot, Paris 7, France; SURVI (Structure d'URgences Vasculaires Intestinales), Intestinal Stroke Center, GHUPNVS, Faculté de Médecine Denis Diderot, Paris 7, France.
    Background And Objectives: Without prompt superior mesenteric artery (SMA) revascularization, acute mesenteric ischemia (AMI) frequently leads to death or short bowel syndrome (SBS). In SBS patients, persistent or chronic intestinal ischemia (PII) of the remnant bowel can lead to recurrences of AMI. Since SMA revascularization is sometimes unfeasible, celiac artery (CA) revascularization may improve blood supply to the remnant bowel. Read More

    Recurrent pericarditis: a case report and literature review.
    Acta Med Litu 2017 ;24(3):159-166
    Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
    Background: Recurrence affects about 30% (20% to 50%) of patients within 18 months after the initial episode of acute pericarditis resulting in subsequent rehospitalizations. Bearing in mind high treatment costs of patients admitted to hospital with acute and recurrent pericarditis, there is a need to optimize the treatment of both of these conditions.

    Materials And Methods: We present a case of recurrent pericarditis. Read More

    Meningococcal arthritis and myopericarditis: a case report.
    BMC Infect Dis 2017 Dec 6;17(1):751. Epub 2017 Dec 6.
    Charing Cross Hospital, Imperial College Healthcare NHS Trust, Fulham Palace Road, London, W6 8RF, UK.
    Background: We report the first adult case of Neisseria meningitidis W-135 presenting with meningococcal arthritis and myopericarditis concomitantly, without other classical features of meningococcal disease.

    Case Presentation: A 67-year-old Caucasian man presented with acute-onset polyarthralgia, myalgia, and fever. On examination he had polyarticular synovitis. Read More

    Recurrent pericarditis.
    Duodecim 2017;133(4):397-401
    Recurrent pericarditis is the most common and problematic complication of acute pericarditis. After acute pericarditis, the pericarditis recurs in 20 to 50% of the patients. In most cases the etiology of pericarditis remains unclear, although it is generally thought to arise by an immunological mechanism. Read More

    Acute pericarditis.
    Duodecim 2017;133(4):391-6
    Acute pericarditis is typically associated with a viral infection. Chest pain appearing in connection with or soon after the symptoms of infection is the characteristic symptom. Diagnosis is based on the recognition of two characteristic findings (pericardial chest pain, pericardial friction rub, new ECG changes or new pericardial effusion). Read More

    Does colchicine decrease the rate of recurrence of acute idiopathic pericarditis treated with glucocorticoids?
    J Cardiol 2017 Nov 30. Epub 2017 Nov 30.
    Department of Cardiology, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
    Background: The traditional treatment of acute pericarditis includes non-steroidal anti-inflammatory agents (NSAIDs) or glucocorticoids. The addition of colchicine has been found to reduce the rate of recurrences. Glucocorticoids, however, may attenuate this effect, although the available data are limited. Read More

    Acute Myopericardial Syndromes.
    Cardiol Clin 2018 Feb;36(1):103-114
    Department of Cardiology, Baylor University Medical Center, Baylor Jack and Jane Hamilton Heart and Vascular Hospital, 621 Hall Street, Dallas, TX 75226, USA; Division of Cardiology, Department of Medicine, Texas A&M College of Medicine, 3302 Gaston Avenue, Dallas, TX 75246, USA.
    Acute myopericardial syndromes are common but can be challenging to manage and potentially have life-threatening complications. Careful clinical history, physical examination, electrocardiogram interpretation, and application of diagnostic criteria are needed to make an accurate diagnosis, exclude concomitant disease, and properly treat patients. Therapy for acute pericarditis should be guided per the underlying cause. Read More

    Pericardial-esophageal Fistula Complicating Atrial Fibrillation Ablation Successfully Resolved after Pericardial Drainage with Conservative Management.
    Korean Circ J 2017 Nov 17;47(6):970-977. Epub 2017 Oct 17.
    Department of Thoracic Surgery, Cardio-Cerebrovascular Center, Dong-A University Hospital, Busan, Korea.
    A 40-year-old male patient underwent radiofrequency catheter ablation for symptomatic paroxysmal atrial fibrillation (AF). Although pulmonary vein (PV) isolation was successfully completed without acute complications, the patient began complaining of sustained retrosternal pain. Seventeen days after ablation, the patient visited the emergency room with fever and severe chest pain with pericarditis-like features. Read More

    Acute pancreatitis in hand, foot and mouth disease caused by Coxsackievirus A16: case report.
    Korean J Pediatr 2017 Oct 20;60(10):333-336. Epub 2017 Oct 20.
    Department of Pediatrics, Hallym University Sacred Heart Hospital, Anyang, Korea.
    Coxsackievirus A16 (CA16), which primarily causes hand, foot, and mouth disease (HFMD), is associated with complications, such as encephalitis, acute flaccid paralysis, myocarditis, pericarditis, and shock. However, no case of pancreatitis associated with CA16 has been reported in children. We report a case of CA16-associated acute pancreatitis in a 3-year-old girl with HFMD. Read More

    Acute Pericarditis Following Acute Pulmonary Thromboembolism.
    Int Heart J 2017 Dec 17;58(6):1028-1033. Epub 2017 Nov 17.
    Division of Internal Medicine, Kurobe City Hospital.
    We describe the case of a 45-year-old Japanese man who developed acute pericarditis following an acute pulmonary thromboembolism. He had developed shortness of breath 7 days prior to hospitalization and was admitted with severe dyspnea. Echocardiography and laboratory results were compatible with acute pulmonary thromboembolism, which was confirmed by contrast-enhanced chest computed tomography. Read More

    Phase 1 study of quizartinib in combination with induction and consolidation chemotherapy in patients with newly diagnosed acute myeloid leukemia.
    Am J Hematol 2018 Feb 4;93(2):213-221. Epub 2017 Dec 4.
    Leukemia Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College, New York, New York.
    Novel therapies have potential to improve outcomes in patients with acute myeloid leukemia (AML) harboring FLT3-ITD mutations that have high risk of relapse and poor survival following standard of care (SOC) cytarabine/anthracycline-based induction/consolidation chemotherapy. Quizartinib is a selective and highly potent FLT3 inhibitor that has shown strong single-agent activity in relapsed or refractory (R/R) AML. This phase 1, open-label, sequential group dose-escalation trial (NCT 01390337) is the first evaluating safety and tolerability of quizartinib in combination with SOC chemotherapy in newly diagnosed AML (ndAML). Read More

    A systematic review of the efficacy and safety of intrapericardial fibrinolysis in patients with pericardial effusion.
    Int J Cardiol 2018 Jan 6;250:223-228. Epub 2017 Nov 6.
    Department of Medicine, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa. Electronic address:
    Pericardial effusion is the abnormal accumulation of fluid in the pericardial space. The complications of pericardial effusion can either be acute (e.g. Read More

    Trends in Acute Pericarditis Hospitalizations and Outcomes among the Elderly in the United States, 1999 - 2012.
    Eur Heart J Qual Care Clin Outcomes 2017 Nov 2. Epub 2017 Nov 2.
    Center for Outcomes Research and Evaluation, Yale-New Haven Hospital, New Haven, CT.
    Aim: The elderly are at risk of pericarditis from conditions such as malignancy, renal disease and after cardiac surgery. However, the burden of pericarditis and especially long-term outcomes associated with pericarditis have not been described before among the elderly.

    Methods And Results: We examined hospitalization rates; in-hospital, 30-day, and 1-year all-cause mortality rates; all-cause 30-day readmission rates; length of stay and healthcare expenditure for Medicare beneficiaries aged 65 years or older with a principal discharge diagnosis of pericarditis from 1999 to 2012. Read More

    Cardiovascular disease in patients with autoinflammatory syndromes.
    Rheumatol Int 2018 Jan 1;38(1):37-50. Epub 2017 Nov 1.
    Academic Research Unit, 2nd Department of Internal Medicine, Kepler University Hospital, Med Campus III, Krankenhausstr. 9, 4020, Linz, Austria.
    Autoinflammatory syndromes (AIS) are characterized by recurring events of inflammation, leading to a variety of organ manifestations and fever attacks. A subgroup of AIS is commonly referred to as hereditary periodic fever syndromes (HPFS). There is substantial evidence that autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus are strongly associated with cardiovascular morbidity and mortality. Read More

    Pericarditis associated with cytarabine therapy for acute myelocytic leukemia: a case report.
    Eur J Clin Pharmacol 2018 Feb 27;74(2):181-182. Epub 2017 Oct 27.
    Department of Hematology, Peking University Third Hospital, Beijing, 100191, China.
    Background: The incidence of cytarabine-induced pericarditis is rare. So far, only a few cases have been reported worldwide.

    Description Of The Case: We are reporting a case of a 25-year-old male with acute myeloid leukemia (AML M2a) on chemotherapy who developed acute pericarditis after the administration of a cytarabine-containing regimen. Read More

    Multimodality Imaging of Pericardial Diseases.
    Curr Treat Options Cardiovasc Med 2017 Oct 12;19(12):89. Epub 2017 Oct 12.
    King Abdulaziz Cardiac Center, King Abdulaziz Medical City, Ministry of National Guard - Health Affairs, Riyadh, Saudi Arabia.
    Opinion Statement: Pericardial diseases have changed their epidemiology in the past few years. With the aging population and decreasing incidence of communicable diseases, the causes of pericardial diseases have significantly changed from infectious and malignant to postradiation and cardiac surgery causes. Despite that, pericardial diseases remain difficult to diagnose. Read More

    Tuberculous and Infectious Pericarditis.
    Cardiol Clin 2017 Nov;35(4):615-622
    Division of Cardiology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Heart Vascular and Stroke Institute Imaging Center, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Republic of Korea. Electronic address:
    Viral pericarditis is the most common cause of acute pericarditis and it is typically responsive to aspirin or nonsteroidal anti-inflammatory drugs. Tuberculous pericarditis is common in immunocompromised patients or in immunocompetent patients in endemic areas. The diagnosis of tuberculous pericarditis usually requires a multidisciplinary approach, and presumptive treatment should be started for people with suspected infections living in endemic areas. Read More

    Acute and Recurrent Pericarditis.
    Cardiol Clin 2017 Nov;35(4):505-513
    Department of Medical Sciences, University Cardiology, AOU Città della Salute e della Scienza di Torino, Corso Bramante 88/90, Torino 10126, Italy.
    Acute and recurrent pericarditis is the most common pericardial syndrome encountered in clinical practice either as an isolated process or as part of a systemic disease. The diagnosis is based on clinical evaluation, electrocardiogram, and echocardiography. The empiric therapy is based on nonsteroidal anti-inflammatory drugs plus colchicine as first choice, resorting to corticosteroids for specific indications (eg, systemic inflammatory disease on corticosteroids, pregnancy, renal failure, concomitant oral anticoagulants), for contraindications or failure of the first-line therapy. Read More

    Imaging of the Pericardium: A Multimodality Cardiovascular Imaging Update.
    Cardiol Clin 2017 Nov;35(4):491-503
    Section of Cardiovascular Imaging, Center for the Diagnosis and Treatment of Pericardial Diseases, Heart and Vascular Institute, Cleveland Clinic, Desk J1-5, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Electronic address:
    Pericardial diseases represent diverse conditions, ranging from painful inflammatory states, such as acute pericarditis, to life-threatening tamponade and chronic heart failure due to constrictive pericarditis. Multimodality cardiovascular imaging plays important roles in diagnosis and management of pericardial conditions. This review provides a clinical update on multimodality cardiovascular imaging of the pericardium, incorporating echocardiography, multidetector computed tomography, and cardiac magnetic resonance imaging, focusing on guiding clinicians about when each cardiac imaging modality should be used in each relevant pericardial condition. Read More

    Cardiac Auscultation for Noncardiologists: Application in Cardiac Rehabilitation Programs: PART I: PATIENTS AFTER ACUTE CORONARY SYNDROMES AND HEART FAILURE.
    J Cardiopulm Rehabil Prev 2017 Aug 4. Epub 2017 Aug 4.
    Preventive Cardiology and Rehabilitation, Istituto Codivilla-Putti, Cortina d'Ampezzo (BL), Italy (Drs Compostella, Compostella, Russo, Setzu, and Bellotto); Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padova, Italy (Drs Compostella, Russo, Iliceto, and Bellotto); and Department of Medicine, School of Emergency Medicine, University of Padua, Padova, Italy (Dr Compostella).
    During outpatient cardiac rehabilitation after an acute coronary syndrome or after an episode of congestive heart failure, a careful, periodic evaluation of patients' clinical and hemodynamic status is essential. Simple and traditional cardiac auscultation could play a role in providing useful prognostic information.Reduced intensity of the first heart sound (S1), especially when associated with prolonged apical impulse and the appearance of added sounds, may help identify left ventricular (LV) dysfunction or conduction disturbances, sometimes associated with transient myocardial ischemia. Read More

    [Angina Pectoris in a Young Woman with Lupus Erythematosus].
    Dtsch Med Wochenschr 2017 Sep 22;142(19):1449-1452. Epub 2017 Sep 22.
    Klinik III für Innere Medizin, Herzzentrum, Universität zu Köln, Köln.
    History and clinical findings We present a 31-year old woman with a 6-year history of cutaneous lupus erythematosus (CLE) who presented to the emergency room with typical chest pain. ECG and transthoracic echocardiography were normal. Her working diagnosis of pericarditis was made due to systemic progression of her lupus erythematosus (LE). Read More

    Diagnosis of systemic inflammatory diseases among patients admitted for acute pericarditis with pericardial effusion.
    J Cardiovasc Med (Hagerstown) 2017 Nov;18(11):875-880
    aDépartement de Médecine Interne bDépartement d'Epidémiologie et Recherche Clinique cDépartement d'Information Médicale dDépartement de Cardiologie, Hôpital Bichat, Université Paris Diderot, PRES Sorbonne Paris Cité, Assistance Publique Hôpitaux de Paris eINSERM U1149 fDépartement Hospitalo-Universitaire FIRE (Fibrosis, Inflammation and Remodelling in Renal and Respiratory Diseases), Paris, France.
    Aims: Acute pericarditis may be the heralding manifestation of various systemic inflammatory diseases (SIDs). The aim of this study was to identify clinical indicators for SIDs in patients admitted for acute pericarditis with pericardial effusion.

    Methods: All consecutive adult patients hospitalized in a Department of Internal Medicine over a 10-year period for acute pericarditis with pericardial effusion were retrospectively reviewed. Read More

    Acute Pericarditis: Descriptive Study and Etiology Determination in a Predominantly African American Population.
    Cureus 2017 Jul 6;9(7):e1431. Epub 2017 Jul 6.
    Department of Internal Medicine, Howard University Hospital.
    INTRODUCTION ---Acute pericarditis is the most commonly encountered manifestation of pericardial disease (incidence: 0.2 percent to 0.5 percent in hospitalized patients). Read More

    Seasonal patterns of acute and recurrent idiopathic pericarditis.
    Clin Cardiol 2017 Nov 15;40(11):1152-1155. Epub 2017 Sep 15.
    Department of Cardiology, Rabin Medical Center-Beilinson Hospital, Petach Tikva, Israel.
    Background: Idiopathic pericarditis is presumed to result from viral infection. The incidence rates of some viral infections have typical seasonal patterns. The data in the literature on a possible seasonal pattern of acute pericarditis are very limited. Read More

    Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia.
    Case Rep Med 2017 20;2017:6501738. Epub 2017 Aug 20.
    Surgical Consultative Nephrology, UCLA Stone Center, Los Angeles, CA, USA.
    Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatosis, is a pulmonary-renal syndrome affecting small and medium sized blood vessels. The disease has a prevalence in studies ranging from 3 to 15.7 cases per 100,000, with a noted increasing incidence and prevalence in more recent studies. Read More

    Isolation and characterization of pathogenic Vibrio alginolyticus from sea cage cultured cobia (Rachycentron canadum (Linnaeus 1766)) in India.
    Lett Appl Microbiol 2017 Nov;65(5):423-430
    Mandapam Regional Centre, Central Marine Fisheries Research Institute, Mandapam Camp, Tamil Nadu, India.
    Mass mortalities of cobia, Rachycentron canadum, sub-adults occurred during August 2013 in cage culture in the Gulf of Mannar, Mandapam Tamil Nadu, India. The epizootic of disease was started with typical classical clinical signs followed by acute mortality. Grossly, severe haemorrhage and congestion were observed in the gastric mucosa. Read More

    Emergency medicine evaluation and management of the end stage renal disease patient.
    Am J Emerg Med 2017 Dec 5;35(12):1946-1955. Epub 2017 Sep 5.
    Joint Base Elmendorf Richardson Medical Center, Department of Emergency Medicine, 5955 Zeamer Ave, JBER, AK, 99506, United States.
    Background: End stage renal disease (ESRD) is increasing in the U.S., and these patients demonstrate greater all-cause mortality, cardiovascular events, and hospitalization rates when compared to those with normal renal function. Read More

    Thoracic Radiation Normal Tissue Injury.
    Semin Radiat Oncol 2017 Oct;27(4):370-377
    Department of Radiation Oncology, University of Maryland Medical Center, Baltimore, MD. Electronic address:
    Thoracic malignancies are often a difficult group of tumors to treat definitively as the radiation doses needed to achieve a high probability for tumor control are often associated with high rates of radiation-induced toxicities. The lungs are particularly radiosensitive and are susceptible to radiation pneumonitis in the acute and subacute settings and pulmonary fibrosis in the late setting. Acute esophagitis is common and affects patient quality of life. Read More

    Cardiac Auscultation for Noncardiologists: Application in Cardiac Rehabilitation Programs: PART I: PATIENTS AFTER ACUTE CORONARY SYNDROMES AND HEART FAILURE.
    J Cardiopulm Rehabil Prev 2017 Sep;37(5):315-321
    Preventive Cardiology and Rehabilitation, Istituto Codivilla-Putti, Cortina d'Ampezzo (BL), Italy (Drs Compostella, Compostella, Russo, Setzu, and Bellotto); Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padova, Italy (Drs Compostella, Russo, Iliceto, and Bellotto); and Department of Medicine, School of Emergency Medicine, University of Padua, Padova, Italy (Dr Compostella).
    During outpatient cardiac rehabilitation after an acute coronary syndrome or after an episode of congestive heart failure, a careful, periodic evaluation of patients' clinical and hemodynamic status is essential. Simple and traditional cardiac auscultation could play a role in providing useful prognostic information.Reduced intensity of the first heart sound (S1), especially when associated with prolonged apical impulse and the appearance of added sounds, may help identify left ventricular (LV) dysfunction or conduction disturbances, sometimes associated with transient myocardial ischemia. Read More

    Cardiac Auscultation for Noncardiologists: Application in Cardiac Rehabilitation Programs: PART II: ADULT PATIENTS AFTER HEART SURGERY.
    J Cardiopulm Rehabil Prev 2017 Nov;37(6):397-403
    Preventive Cardiology and Rehabilitation, Istituto Codivilla-Putti, Cortina d'Ampezzo, Italy (Drs Compostella, Russo, Compostella, Setzu, and Bellotto); Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padova, Italy (Drs Compostella, Russo, Iliceto, and Bellotto); and Department of Medicine, School of Emergency Medicine, University of Padua, Padova, Italy (Dr Compostella).
    This clinical skills review describes the most common cardiac auscultatory findings in adults after heart surgery and correlates them with prognostic indicators. It was written for noncardiologist health care providers who work in outpatient cardiac rehabilitation programs.Mechanical prosthetic valves produce typical closing and opening clicks. Read More

    [Acute pericarditis, complicated by pericardial effusion in a pediatric patient: case report].
    Arch Argent Pediatr 2017 Aug;115(4):e237-e242
    Hospital Infantil Miguel Servet, Zaragoza, Unidad de Cardiología Pediátrica.
    Acute pericarditis is the most common disease of the pericardium encountered in clinical practice. It is diagnosed in 0.1% of all admissions and 5% of emergency room admissions for chest pain. Read More

    A Case of Primary Bacterial Pericarditis with Recurrent Cardiac Tamponade.
    J Nippon Med Sch 2017 ;84(3):133-138
    Department of Cardiology, Nippon Medical School.
    Cardiac tamponade is an important and potentially lethal complication of acute pericarditis. However, recurrence of cardiac tamponade is rare when it is treated appropriately. We present a 49-year-old man with bacterial pericarditis and recurrent cardiac tamponade, which was caused by the rupture of an upper part of the left atrium (LA). Read More

    Bilateral idiopathic retinal vasculitis following coxsackievirus A4 infection: a case report.
    BMC Ophthalmol 2017 Jul 19;17(1):128. Epub 2017 Jul 19.
    Department of Ophthalmology, National Defense Medical College, 3-2 Namiki, Tokorozawa City, Saitama, 359-8513, Japan.
    Background: Coxsackieviruses are members of a group of viruses called the enteroviruses, which may cause respiratory and gastrointestinal symptoms, erythema, meningoencephalitis, myocarditis, pericarditis, and myositis. Unilateral acute idiopathic maculopathy caused by coxsackievirus A16 has been associated with hand, foot, and mouth disease, but only a few reports describe retinitis associated with coxsackievirus serotype B3 or B4. We report a case of bilateral multifocal obstructive retinal vasculitis that developed after coxsackievirus A4 infection. Read More

    Pericarditis Associated With Acute Zika Virus Infection in a Returning Traveler.
    Open Forum Infect Dis 2017 18;4(2):ofx103. Epub 2017 May 18.
    Divisions of Infectious Diseases and.
    Despite the widespread outbreak, few cases of Zika virus associated with cardiac manifestations have been described. We present a case of pericarditis in the setting of an acute, symptomatic Zika virus infection in a traveler returning from St. Thomas. Read More

    Cytopathology of pericardial effusions : Experience from a tertiary center of cardiology.
    Herz 2017 Jul 10. Epub 2017 Jul 10.
    Department of Cardiology, Kartal Kosuyolu Heart & Research Hospital, 34846, Istanbul, Turkey.
    Background: Pericardial effusion (PE) is a common clinical condition that can develop as a result of systemic or cardiac diseases. Here, we report the results of cytology for patients who underwent pericardiocentesis for PE.

    Methods: The study comprised 283 patients who underwent primary percutaneous pericardiocentesis between 2007 and 2016. Read More

    Cardiovascular and Pulmonary Manifestations of Systemic Lupus Erythematosus.
    Curr Rheumatol Rev 2017 ;13(3):206-218
    Centre for Prognosis Studies in the Rheumatic Diseases, Toronto Lupus Clinic, University Health Network, Toronto, Ontario. Canada.
    Background: Systemic lupus erythematosus (SLE) is characterized by various clinical manifestations and immunologic abnormalities. Cardiovascular and respiratory system involvement are increasingly recognized as critical for patients' prognosis. In this review, current knowledge concerning diagnosis, pathogenesis and treatment of the cardiac and pulmonary lupus manifestations are discussed. Read More

    Pericarditis as a Marker of Occult Cancer and a Prognostic Factor for Cancer Mortality.
    Circulation 2017 Sep 29;136(11):996-1006. Epub 2017 Jun 29.
    From Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Denmark (K.K.S., D.K.F., V.E., H.T.S.); Non-Communicable Diseases Epidemiology, London School of Hygiene and Tropical Medicine, United Kingdom (K.B.) Department of Cardiology, Aarhus University Hospital, Skejby, Denmark (H.E.B.); and Department of Health Research and Policy (Epidemiology), Stanford University, CA (H.T.S.).
    Background: Pericarditis may be a serious complication of malignancy. Its significance as a first symptom of occult cancer and as a prognostic factor for cancer survival is unknown.

    Methods: Using Danish medical databases, we conducted a nationwide cohort study of all patients with a first-time diagnosis of pericarditis during 1994 to 2013. Read More

    The Therapeutic Role of Interleukin-1 Inhibition in Idiopathic Recurrent Pericarditis: Current Evidence and Future Challenges.
    Front Med (Lausanne) 2017 12;4:78. Epub 2017 Jun 12.
    Joint Rheumatology Program, Clinical Immunology-Rheumatology Unit, 2nd Department of Medicine and Laboratory, School of Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
    Recurrent pericarditis is a common complication of acute pericarditis (15-30%) for which, in most cases, no underlying etiology is found [idiopathic recurrent pericarditis (IRP)]. IRP is currently viewed as an autoinflammatory disease with characteristic recurrent episodes of sterile inflammation. According to the most recent Guidelines, the initial treatment regimen consists of a combination of aspirin or non-steroidal anti-inflammatory drugs with colchicine followed by the addition of corticosteroids in resistant or intolerant cases. Read More

    A Rare Case of Pneumopericardium in the Setting of Tuberculous Constrictive Pericarditis.
    Case Rep Cardiol 2017 28;2017:4257452. Epub 2017 May 28.
    Division of Thoracocardiovascular Surgery, Department of Surgery, University of the Philippines, Philippine General Hospital, Manila, Philippines.
    A 28-year-old Filipino male was admitted due to high-grade fevers and dyspnea on a background of chronic cough and weight loss. Due to clinical and echocardiographic signs of cardiac tamponade, emergency pericardiocentesis was performed on his first hospital day. Five days after, chest radiographs showed new pockets of radiolucency within the cardiac shadow, indicative of pneumopericardium. Read More

    Interleukin-1 blockade for the treatment of pericarditis.
    Eur Heart J Cardiovasc Pharmacother 2018 Jan;4(1):46-53
    VCU Pauley Heart Center, Virginia Commonwealth University, 1200 E Broad Street, 5th Floor Rm 520, Richmond, VA 23298, USA.
    Pericarditis is a debilitating condition that results from profound inflammation of the pericardial tissue. Between 10 and 15% of first episodes of acute pericarditis will be followed by several episodes refractory to conventional treatment. Current standard of care for pericarditis treatment includes high-dose non-steroidal anti-inflammatory drugs, colchicine, and systemic corticosteroids, each associated with potentially severe toxicities and nominal efficacy. Read More

    Citrobacter freundii as a cause of acute suppurative thyroiditis in an immunocompetent adult female.
    Indian J Pathol Microbiol 2017 Apr-Jun;60(2):282-284
    Department of Otorhinolaryngology, Government Medical College Hospital, Chandigarh, India.
    Acute suppurative thyroiditis (AST) is an uncommon condition, in the patients with preexisting thyroid disease or immunosuppression. The most common cause of AST is bacterial, and the most common bacteria are Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Klebsiella species. Due to various complications such as septicemia, septic thrombophlebitis, necrotizing mediastinitis, or pericarditis, prompt diagnosis and treatment are the keys to reduce mortality and morbidity. Read More

    Invasive Hemodynamics of Pericardial Disease.
    Interv Cardiol Clin 2017 Jul;6(3):309-317
    Valve Science Center, Minneapolis Heart Institute Foundation, 800 East 28th Street, Minneapolis, MN 55407, USA; Center for Valve and Structural Heart Disease, Minneapolis Heart Institute, Abbott Northwestern Hospital, 800 East 28th Street, Minneapolis, MN 55407, USA. Electronic address:
    Pericardial diseases can be classified broadly as 3 entities: acute pericarditis, cardiac tamponade, and constrictive pericarditis. These disorders can be diagnosed and managed with noninvasive studies following a comprehensive history and physical examination, without the need for cardiac catheterization in most patients. Despite the advances in noninvasive cardiac imaging, there are limitations to their diagnostic accuracy. Read More

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