12,907 results match your criteria Pericardial Effusion


Pembrolizumab plus trastuzumab in trastuzumab-resistant, advanced, HER2-positive breast cancer (PANACEA): a single-arm, multicentre, phase 1b-2 trial.

Lancet Oncol 2019 Feb 11. Epub 2019 Feb 11.

Institut Gustave Roussy, Université Paris Sud, INSERM U981, Villejuif, France.

Background: HER2-positive breast cancers usually contain large amounts of T-cell infiltrate. We hypothesised that trastuzumab resistance in HER2-positive breast cancer could be mediated by immune mechanisms. We assessed the safety and anti-tumour activity of pembrolizumab, a programmed cell death protein 1 (PD-1) inhibitor, added to trastuzumab in trastuzumab-resistant, advanced HER2-positive breast cancer. Read More

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http://dx.doi.org/10.1016/S1470-2045(18)30812-XDOI Listing
February 2019

Targeted Cancer Therapies With Pericardial Effusions Requiring Pericardiocentesis Focusing on Immune Checkpoint Inhibitors.

Am J Cardiol 2019 Jan 25. Epub 2019 Jan 25.

Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Case reports have reported immune checkpoint inhibitors (ICI), especially nivolumab, are associated with recurrent pericardial effusions. Our objective was to determine how often patients being treated with ICI develop hemodynamically significant pericardial effusion requiring pericardiocentesis compared with other cancer therapeutics and whether the survival of patients who underwent pericardiocentesis differs according to ICI use versus standard cancer therapeutics. Our institutional review board approved catheterization laboratory data collection for all pericardiocenteses performed and all patients receiving ICI from January 1, 2015 to December 31, 2017. Read More

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http://dx.doi.org/10.1016/j.amjcard.2019.01.013DOI Listing
January 2019

High Morbidity Due to Murine Typhus Upsurge in Urban Neighborhoods in Central Israel.

Am J Trop Med Hyg 2019 Feb 11. Epub 2019 Feb 11.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

The incidence of murine typhus in Israel has decreased substantially since 1950 to a low of 0.04/100,000 population in 2010. We present the experience of a single university medical center in central Israel. Read More

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http://dx.doi.org/10.4269/ajtmh.18-0076DOI Listing
February 2019

Cardiac Manifestations in Systemic Lupus Erythematosus: Clinical Correlates of Subclinical Echocardiographic Features.

Biomed Res Int 2019 10;2019:2437105. Epub 2019 Jan 10.

Rheumatology Department, Faculty of Medicine, Cairo University, Giza, Egypt.

Objectives: This study aims to correlate subclinical echocardiographic features with the clinical, laboratory, and therapeutic profiles of the patients to characterize risks for systemic lupus erythematosus (SLE) cardiac diseases.

Methods: The study included 59 SLE patients. Demographic data, disease characteristics, and current therapies were recorded, and the anthropometric measurements and routine laboratory tests were performed. Read More

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http://dx.doi.org/10.1155/2019/2437105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348873PMC
January 2019

The occurrence of cardiac abnormalities in canine steroid-responsive meningitis arteritis.

J Small Anim Pract 2019 Feb 11. Epub 2019 Feb 11.

Small Animal Hospital, University of Glasgow, Glasgow G61 1QH, UK.

Objectives: To document the prevalence of cardiac abnormalities in dogs with steroid-responsive meningitis arteritis and to assess resolution of these abnormalities following corticosteroid therapy.

Materials And Methods: Steroid-responsive meningitis arteritis was diagnosed based on signalment, physical examination findings, complete blood count, biochemistry and CSF analysis. Echocardiography, C-reactive protein and cardiac troponin I were measured in all cases before and 10 to 14 days after commencing corticosteroid therapy. Read More

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http://dx.doi.org/10.1111/jsap.12984DOI Listing
February 2019
1 Read

Outcomes of minimally invasive sleeve resection.

J Thorac Dis 2018 Dec;10(12):6653-6659

Division of Thoracic Surgery, MedStar Georgetown University Hospital, Washington, DC, USA.

Background: Sleeve resection allows for preservation of lung parenchyma and improved long-term outcomes when compared with pneumonectomy. Little is known about minimally invasive sleeve resection, especially indications, feasibility, technical aspects, complications, and outcomes. We reviewed our institutional experience with sleeve resections via a minimally invasive approach. Read More

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http://jtd.amegroups.com/article/view/25146/19447
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http://dx.doi.org/10.21037/jtd.2018.10.97DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344683PMC
December 2018
2 Reads

Diagnostic value of acid phosphatases (ACP) in differentiating reactive mesothelial cells from cancer cells in the body fluid effusions.

J Thorac Dis 2018 Dec;10(12):6446-6451

Department of Pathology, The First Affiliated Hospital and College of Basic Medical Sciences, China Medical University, Shenyang 110001, China.

Background: The cytological diagnosis of a malignant epithelial tumor, i.e., a cancer cell in the body fluid effusions is usually made by cytomorphological examination alone; however, diagnostic challenges can occur when the cancer cells are rare or cytological atypia is minimal. Read More

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http://dx.doi.org/10.21037/jtd.2018.11.64DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6344779PMC
December 2018
1 Read

Effect of pericardial effusion on outcomes in children admitted with systemic lupus erythematosus: a multicenter retrospective cohort study from the United States.

Lupus 2019 Feb 11:961203319828523. Epub 2019 Feb 11.

1 University of Arkansas for Medical Sciences and Arkansas Children's Research Institute, Little Rock AR, USA.

Objective: We sought to describe characteristics of children admitted with pericardial effusion (PCE) and systemic lupus erythematosus (SLE) and determine the association between PCE and outcomes of interest.

Methods: We performed a retrospective cohort study of the Pediatric Health Information System (PHIS). Patients were included if they were admitted to a PHIS participating hospital from 2004 to 2015 with a diagnosis of SLE and age ≤18 years. Read More

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http://dx.doi.org/10.1177/0961203319828523DOI Listing
February 2019
1 Read

Superior Vena Cava Cancerous Thrombus Due to Squamous Cell Tongue Cancer: Virchow's Triad at Its Worst Version.

Thromb Haemost 2019 Feb 11. Epub 2019 Feb 11.

Department of Critical Care, University Hospital of Larissa, Thessaly, Greece.

Superior vena cava (SVC) cancerous thrombosis is extremely sparse, especially in the setting of extrathoracic tumours. Herein, we present the case of a patient with a squamous cell carcinoma of the tongue, who presented with SVC syndrome possibly secondary to symptomatic metastatic pericardial effusion. In this unique patient, the disastrous concurrence of all the elements of Virchow's triad within the confined anatomical space of SVC may have precipitated extensive vessel thrombosis with catastrophic consequences. Read More

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http://dx.doi.org/10.1055/s-0039-1677712DOI Listing
February 2019
1 Read

Anaplastic Lymphoma Kinase (ALK)-positive Tumors: Clinical, Radiographic and Molecular Profiles, and Uncommon Sites of Metastases in Patients With Lung Adenocarcinoma.

Am J Clin Oncol 2019 Feb 5. Epub 2019 Feb 5.

Department of Medical Oncology and Therapeutic Research, City of Hope National Medical Center, Duarte, CA.

Introduction: Anaplastic lymphoma kinase (ALK) gene rearrangements are observed in about 4% to 8% non-small cell lung cancer (NSCLC). ALK+ tumors have been associated with increased pleural and pericardial disease. Our primary objective was to determine the uncommon sites of metastasis of ALK+ NSCLC. Read More

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http://dx.doi.org/10.1097/COC.0000000000000508DOI Listing
February 2019
1 Read

Electroanatomic mapping-guided catheter ablation of atrial tachycardia in children with limited/zero fluoroscopy.

Pacing Clin Electrophysiol 2019 Feb 10. Epub 2019 Feb 10.

Department of Pediatric Cardiology/Electrophysiology, Istanbul Medipol University Hospital, Istanbul, Turkey.

Introduction: Atrial tachycardia (AT) is an uncommon cause of supraventricular tachycardia in children and it is often resistant to medical therapy. Catheter ablation can be curative in children with AT. However, experience of ablation of pediatric AT is still very limited. Read More

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http://doi.wiley.com/10.1111/pace.13619
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http://dx.doi.org/10.1111/pace.13619DOI Listing
February 2019
2 Reads

Differentiation malignant from benign pericardial effusion with diffusion-weighted MRI.

Clin Radiol 2019 Feb 6. Epub 2019 Feb 6.

Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Masnoura, Egypt.

Aim: To differentiate malignant from benign pericardial effusion with diffusion-weighted magnetic resonance imaging (MRI).

Material And Methods: Retrospective analysis of diffusion-weighted MRI of 41 patients (29 men and 12 women; mean 39 years) with pericardial effusion. Apparent diffusion coefficient (ADC) of pericardial fluid, and associated pericardial mass or pleural effusion was calculated. Read More

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http://dx.doi.org/10.1016/j.crad.2019.01.005DOI Listing
February 2019
1 Read

Cardiovascular findings on cross-sectional imaging: spectrum of incidental and critical findings and clinical relevance for the abdominal radiologist.

Abdom Radiol (NY) 2019 Feb 8. Epub 2019 Feb 8.

Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

Although not the primary focus of the exams, cardiovascular structures are included to some extent on all abdominal or whole-body cross-sectional studies. Cardiovascular findings often present incidentally and may range from chronic to acute and emergent pathologies. Among the most common cardiovascular findings are the presence of cardiac calcifications, most commonly coronary, which correlate with the presence of coronary artery and valvular disease. Read More

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http://dx.doi.org/10.1007/s00261-019-01922-7DOI Listing
February 2019

Midline carcinoma expressing NUT in malignant effusion cytology.

Diagn Cytopathol 2019 Feb 8. Epub 2019 Feb 8.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, California.

Nuclear protein in testis (NUT) midline carcinoma (NMC) is a rare and aggressive subset of poorly differentiated squamous cell carcinoma that is defined by t(15,19) and typically presents in the midline structures of the head, neck, and mediastinum. We report two cases of NMC that presented uniquely with malignant pleural and pericardial effusions including one with cardiac tamponade at presentation. The first case is of a 25-year-old male patient who presented with progressive dyspnea associated with palpitations and dizziness on standing, found to have large bilateral pleural effusions. Read More

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http://doi.wiley.com/10.1002/dc.24150
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http://dx.doi.org/10.1002/dc.24150DOI Listing
February 2019
5 Reads

Non-parallel anti-tumour effects of pembrolizumab: a case of cardial tamponade.

Respirol Case Rep 2019 Apr 31;7(3):e00404. Epub 2019 Jan 31.

Division of Respiratory Medicine, Department of Internal Medicine Kobe University Graduate School of Medicine Kobe Japan.

We present the case of a 70-year-old man with stage IV lung adenocarcinoma. He was treated with pembrolizumab, a programmed cell death-1 (PD-1) inhibitor, as a first-line therapy. After six cycles of pembrolizumab, he suddenly developed cardiac tamponade. Read More

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http://dx.doi.org/10.1002/rcr2.404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354230PMC
April 2019
1 Read

Relapse of multiple myeloma presenting as pericardial effusion.

Blood 2019 Feb;133(6):619

Centre Hospitalier Universitaire Lille.

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http://dx.doi.org/10.1182/blood-2018-11-884221DOI Listing
February 2019
1 Read

Transseptal Puncture for Catheter Ablation in Children.

Pediatr Cardiol 2019 Feb 7. Epub 2019 Feb 7.

Department of Pediatric Cardiology/Electrophysiology, Istanbul Medipol University Hospital, Istanbul, Turkey.

Transseptal puncture (TP) is used in pediatric patients to access the left atrium in left-sided arrhythmia catheter ablation. Performing this procedure can be difficult and risky, especially in small children. In this study, we aimed to evaluate the safety and feasibility of TPs in children ≤ 30 kg. Read More

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http://link.springer.com/10.1007/s00246-019-02069-4
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http://dx.doi.org/10.1007/s00246-019-02069-4DOI Listing
February 2019
4 Reads

Cardiac Tamponade as an Initial Manifestation of Cervical Cancer.

Case Rep Oncol Med 2019 9;2019:7524797. Epub 2019 Jan 9.

Universidad Autónoma de Nuevo Leon, Facultad de Medicina y Hospital Universitario "Dr. José Eleuterio González", Department of Pathology, Av. Madero y Gonzalitos s/n, Colonia Mitras Centro, Monterrey, Nuevo Leon, C.P. 64460, Mexico.

Cervical cancer is the second most common malignancy worldwide in women and the third most common cause of cancer death in developing countries. This type of cancer spreads mainly to the lung, the bone, and the brain; however, the pericardium is an unusual site of invasion, which is associated with a poor prognosis. We present a case of a 35-year-old woman with six months of leg edema and abnormal uterine bleeding. Read More

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http://dx.doi.org/10.1155/2019/7524797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343150PMC
January 2019
2 Reads

Management of cardiac tamponade during nivolumab of lung cancer with intrapericardial bleomycin: case report.

Immunotherapy 2019 Feb 7. Epub 2019 Feb 7.

Department of Thoracic Oncology & Respiratory Medicine, Tokyo Metropolitan Cancer & Infectious Diseases Center, Komagome Hospital, Bunkyo, Tokyo, Japan.

Immuno-checkpoint inhibitor response and immune-related adverse events remain controversial issues. Managing pericardial effusion during programmed cell death 1 inhibitor treatment is challenging. Here, we report a case of successfully managed cardiac tamponade caused by nivolumab-induced pseudoprogression. Read More

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http://dx.doi.org/10.2217/imt-2019-0003DOI Listing
February 2019
2 Reads

Primary tumour resection in non-small-cell lung cancer patients with ipsilateral pleural dissemination (M1a): a population-based study.

Eur J Cardiothorac Surg 2019 Feb 4. Epub 2019 Feb 4.

Department of Thoracic Surgery, Centre of Thoracic Minimally Invasive Surgery, Peking University People's Hospital, Beijing, China.

Objectives: Non-small-cell lung cancer (NSCLC) patients with ipsilateral pleural dissemination (M1a) are generally contraindicated for surgery. However, several small-sample studies have demonstrated that they might benefit from surgery. We investigated the effects of primary tumour resection on survival in these patients. Read More

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http://dx.doi.org/10.1093/ejcts/ezy439DOI Listing
February 2019
1 Read

Unusual Case of Recurrent Pericardial Effusion - Erdheim-Chester Disease.

Circ J 2019 Feb 6. Epub 2019 Feb 6.

Division of Cardiology, Severance Cardiovascular Hospital, Cardiovascular Research Institute.

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http://dx.doi.org/10.1253/circj.CJ-18-1223DOI Listing
February 2019

Pericardial Effusion With Tamponade in Lung Cancer Patients During Treatment With Nivolumab: A Report of Two Cases.

Front Oncol 2019 22;9. Epub 2019 Jan 22.

Department of Molecular and Internal Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

Nivolumab is an immune checkpoint inhibitor (ICI) that has shown efficacy for treating non-small cell lung cancer and has become a standard therapy for previously treated non-small cell lung cancer. Moreover, immune-related adverse events of ICI therapy are well-known. Malignant pericardial effusions occasionally arise in patients with lung cancer. Read More

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http://dx.doi.org/10.3389/fonc.2019.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349695PMC
January 2019

Off-label use of duct occluder in transcatheter closure of secundum atrial septal defect with no rim to right pulmonary vein.

J Thorac Cardiovasc Surg 2018 Dec 12. Epub 2018 Dec 12.

Radiology Imaging Center, Cardiovascular Institute and Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Objective: Transcatheter closure is usually contraindicated in secundum atrial septal defect with no rim to right pulmonary vein. The morphology of an atrial septal defect is special in these patients, and the off-label use of a duct occluder might make transcatheter closure possible with the assistance of a personalized heart model. However, the related data are absent. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2018.11.093DOI Listing
December 2018
1 Read

Tolerability and activity of ublituximab, umbralisib, and ibrutinib in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: a phase 1 dose escalation and expansion trial.

Lancet Haematol 2019 Feb;6(2):e100-e109

The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: Therapeutic approaches for B-cell malignancies continue to evolve, especially with regard to combination approaches. We assessed the safety and efficacy of the triplet ublituximab, umbralisib, and ibrutinib in patients with advanced B-cell malignancies.

Methods: We did an open-label, phase 1 study with dose-escalation and dose-expansion phases, at five centres in the USA. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23523026183021
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http://dx.doi.org/10.1016/S2352-3026(18)30216-3DOI Listing
February 2019
3 Reads

[Acute myeloid leukemia with malignant pericardial effusion: two cases report].

Zhonghua Xue Ye Xue Za Zhi 2019 Jan;40(1):76

Department of Hematology, the Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Zhengzhou 450008, China.

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http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2019.01.015DOI Listing
January 2019
1 Read

Exudative-constrictive tuberculous pericarditis in combination with arthritis in cardiologist practice: thoracoscopic biopsy as a diagnosis and treatment method.

Ter Arkh 2018 Sep;90(9):81-87

V.N. Vinogradov Faculty Therapeutic clinic of I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia.

Aim: The goal is to present the possibilities of diagnosis verification, the features of the clinical picture of tuberculous pericarditis in the therapeutic clinic and the results of its treatment.

Materials And Methods: The paper presents clinical observation and a general analysis of 10 cases of tuberculous pericarditis in patients aged 31-79 (mean age 58.0 ± 15. Read More

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http://dx.doi.org/10.26442/terarkh201890981-87DOI Listing
September 2018
2 Reads

Grossly elevated plasma BNP does not exclude the diagnosis of constrictive pericarditis.

Oxf Med Case Reports 2019 Jan 24;2019(1):omy110. Epub 2019 Jan 24.

Frimley Health NHS Foundation Trust, Wexham Park Hospital, Slough, UK.

Pericardial effusion with constrictive physiology describes a condition in which the pericardial fluid and thickened and dense pericardium limit left ventricular (LV) diastolic filling and prevent ventricular stretch. This leads to equalization of the end-diastolic pressure in cardiac chambers and poor ventricular filling. We report two patients, who presented with symptoms and signs of severe heart failure and with significantly raised BNP levels who were subsequently diagnosed to have pericardial effusion with constrictive physiology. Read More

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https://academic.oup.com/omcr/article/doi/10.1093/omcr/omy11
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http://dx.doi.org/10.1093/omcr/omy110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345082PMC
January 2019
3 Reads

Dilated cardiomyopathy with endocardial fibroelastosis in a juvenile Pallas cat.

J Vet Diagn Invest 2019 Jan 29:1040638719827061. Epub 2019 Jan 29.

Departments of Biomedical Sciences and Pathobiology (Gudenschwager, LeRoith), Virginia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA.

Dilated cardiomyopathy (DCM) is a myocardial disease characterized by ventricular chamber dilation associated with systolic myocardial dysfunction in the absence of other cardiac lesions. DCM occasionally develops in conjunction with proliferation of fibroelastic fibers in the endocardium, producing endocardial fibroelastosis (EFE). Although early reports describe EFE as a primary disease, evidence now suggests that EFE may develop as a response to myocardial dysfunction. Read More

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http://dx.doi.org/10.1177/1040638719827061DOI Listing
January 2019
1 Read

An Atypical Biliary Fistula In A Liver Transplant Recipient.

Liver Transpl 2019 Jan 28. Epub 2019 Jan 28.

Division of Hepatology, Baylor University Medical Center, Dallas, TX.

A 55-years-old Caucasian male presented with chest pain, dyspnea and hypotension four-months after simultaneous liver and kidney transplantation. His post-transplant course was complicated with only one episode of acute cellular rejection one month prior to presentation, successfully treated with steroids. His immunosuppression consisted of tacrolimus and mycophenolic acid. Read More

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http://doi.wiley.com/10.1002/lt.25416
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http://dx.doi.org/10.1002/lt.25416DOI Listing
January 2019
4 Reads

Hemodynamics of cardiac tamponade during extracorporeal membrane oxygenation support in a patient with fulminant myocarditis.

J Cardiol Cases 2019 Jan 25;19(1):22-24. Epub 2018 Oct 25.

Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Fulminant myocarditis (FM) causes rapid onset severe heart failure requiring inotropes or mechanical circulatory support. Myocarditis is sometimes associated with pericardial effusion, however, how this effusion affects the hemodynamics in patients with FM under venoarterial extracorporeal membrane oxygenation (VA-ECMO) management has not been fully reported. We show a case of FM presenting with cardiac tamponade during VA-ECMO management. Read More

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http://dx.doi.org/10.1016/j.jccase.2018.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342684PMC
January 2019
1 Read

Mycotic Coronary Aneurysms.

Heart Lung Circ 2018 Dec 19. Epub 2018 Dec 19.

John Hunter Hospital, Newcastle, NSW, Australia.

Background: Mycotic coronary aneurysms (MCA) are rare but often lead to significant morbidity and mortality. Evidence on the topic is limited to case reports and small case series. A systematic review was performed to improve understanding of this challenging diagnosis. Read More

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http://dx.doi.org/10.1016/j.hlc.2018.12.004DOI Listing
December 2018
1 Read

Pericardial effusion due to pembrolizumab-induced immunotoxicity: A case report and literature review.

Curr Probl Cancer 2019 Jan 18. Epub 2019 Jan 18.

Department of Endocrinology, University of California San Francisco, San Francisco, California.

The advent of immune checkpoint inhibitors has revolutionized cancer treatment. These novel agents have provided promising treatment options in patients with different types of cancers. One of these agents is pembrolizumab, which works by blocking the binding of T-lymphocytes to programmed cell death ligand 1 receptors on tumor cells, thus enabling immune activation of T-lymphocytes against tumor cells. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01470272183024
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http://dx.doi.org/10.1016/j.currproblcancer.2019.01.001DOI Listing
January 2019
15 Reads

Role of real time-three dimensional transesophageal echocardiography in left atrial appendage closure with LACBES devices.

Exp Ther Med 2019 Feb 12;17(2):1456-1462. Epub 2018 Dec 12.

Department of Cardiology, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200011, P.R. China.

Catheter-based left atrial appendage closure (LAAC) has recently become an innovative strategy for preventing embolic events in patients with nonvalvular atrial fibrillation (AF). There is limited information on optimal sizing for LAAC with the recently developed LACBES device. The aim of the present study was to assess the role of real time-three dimensional transesophageal echocardiography (RT-3D TEE) for LACBES device selection during LAAC. Read More

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http://dx.doi.org/10.3892/etm.2018.7086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327486PMC
February 2019
1 Read

Light chain cardiac amyloidosis - a rare cause of heart failure in a young adult.

Rev Assoc Med Bras (1992) 2018 Sep;64(9):787-790

. Department of Cardiology, Hospital Distrital de Santarém, Santarém, Portugal.

Cardiac amyloidosis is an infiltrative cardiomyopathy, resulting from amyloid deposition within the myocardium. In primary systemic (AL-type) amyloidosis, the amyloid protein is composed of light chains resulting from plasma-cell dyscrasia, and cardiac involvement occurs in up to 50% of the patients We present a case of a 43-year-old man, with complaints of periodical swollen tongue and xerostomia, bleeding gums and haematuria for two months. His blood results showed normocytic anaemia, thrombocytopenia and a high spontaneous INR, therefore he was referred to the Internal Medicine clinic. Read More

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http://dx.doi.org/10.1590/1806-9282.64.09.787DOI Listing
September 2018
3 Reads

Efficacy of systemic sirolimus in the treatment of generalized lymphatic anomaly and Gorham-Stout disease.

Pediatr Blood Cancer 2019 Jan 22:e27614. Epub 2019 Jan 22.

Vascular Anomalies Center, Division of Hematology/Oncology, Cancer and Blood Disorders Center, Boston Children's Hospital, Boston, Massachusetts.

Background: Generalized lymphatic anomaly (GLA) and Gorham-Stout disease (GSD) are rare complicated lymphatic malformations that occur in multiple body sites and are associated with significant morbidity and mortality. Treatment options have been limited, and conventional medical therapies have been generally ineffective. Emerging data suggest a role for sirolimus as a treatment option for complex lymphatic anomalies. Read More

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http://dx.doi.org/10.1002/pbc.27614DOI Listing
January 2019
1 Read

Incidence and in-hospital Safety Outcomes of Patients undergoing Percutaneous Mitral Valve Edge-to-Edge Repair Using MitraClip® - 5 year German national patient sample including 13,575 implants.

EuroIntervention 2019 Jan 22. Epub 2019 Jan 22.

Heart Valve Center Mainz, Center of Cardiology, Cardiology I, University Medical Center, Mainz, Germany.

Aims: The number of percutaneous edge-to-edge mitral regurgitation valve repairs with MitraClip® implantation increased during the last years. Published studies showed promising safety outcomes in relatively small cohorts, while results from large samples are sparse. Thus, we aimed to evaluate trends and safety outcomes in the German nationwide inpatient sample. Read More

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http://dx.doi.org/10.4244/EIJ-D-18-00961DOI Listing
January 2019
5 Reads

Detection of 21q11.2-q22.11 deletions in a fetus by NIPT.

J Clin Lab Anal 2019 Jan 21:e22711. Epub 2019 Jan 21.

Department of Obstetrics and Gynecology, The First Affiliated Hospital Of Air Force Medical University, Xi'an, Shaanxi, China.

Background: Non-invasive prenatal testing (NIPT) is extensively used in the detection of fetal trisomies 21, 18, and 13, which is promptly becoming a common clinical practice. Concerned about the clinical application of non-invasive detection of the fetal autosomal duplications or deletion.

Case Presentation: A 34-year-old, healthy pregnant woman was referred to the First Affiliated Hospital of the Air Force Medical University. Read More

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http://doi.wiley.com/10.1002/jcla.22711
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http://dx.doi.org/10.1002/jcla.22711DOI Listing
January 2019
6 Reads

Low-fluoroscopy atrial fibrillation ablation with contact force and ultrasound technologies: a learning curve.

Pragmat Obs Res 2019 10;10:1-7. Epub 2019 Jan 10.

Cardiovascular Medicine, Stanford University, Stanford, CA, USA.

Background: Fluoroscopy exposure during catheter ablation is a health hazard to patients and operators. This study presents the results of implementing a low-fluoroscopy workflow using modern contact force (CF) technologies in paroxysmal atrial fibrillation (PAF) ablation.

Methods: A fluoroscopy reduction workflow was implemented and subsequent catheter ablations for PAF were evaluated. Read More

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http://dx.doi.org/10.2147/POR.S181220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330962PMC
January 2019
2 Reads

[Looking for the reason of hemodynamic instability: the role of intraoperative ultrasound - Case report].

Rev Bras Anestesiol 2019 Jan 13. Epub 2019 Jan 13.

Hospital Universitario de Gran Canaria Dr. Negrín, Department of Anesthesiology, Las Palmas de Gran Canaria, Spain; Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.

Background And Objectives: A prompt and effective management of trauma patient is necessary. The aim of this case report is to highlight the importance of intraoperative echocardiography as a useful tool in patients suffering from refractory hemodynamic instability no otherwise explained.

Case Report: A 41 year-old woman suffered a car accident. Read More

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http://dx.doi.org/10.1016/j.bjan.2018.09.012DOI Listing
January 2019
2 Reads

Brugada phenocopy in a patient underdoing pericardiocentesis for a large idiopathic pericardial effusion.

J Electrocardiol 2019 Jan 7. Epub 2019 Jan 7.

First Cardiology Department, Hippokration General Hospital, National and Kapodistrian University of Athens, Greece.

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http://dx.doi.org/10.1016/j.jelectrocard.2019.01.081DOI Listing
January 2019
3 Reads

Oesophagopericardial Fistula after Atrial Fibrillation Catheter Ablation.

J Belg Soc Radiol 2019 Jan 7;103(1). Epub 2019 Jan 7.

Clinique St Luc, Bouge (Namur), BE.

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http://dx.doi.org/10.5334/jbsr.1684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328641PMC
January 2019
1 Read

Pericardial Mesothelioma in a 35-Year-Old Male With Ulcerative Colitis.

Circ Cardiovasc Imaging 2019 Dec;12(1):e008659

Department of Cardiology (J.I., N.K.B., C.J.H.), University of New South Wales, Sydney, Australia.

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http://dx.doi.org/10.1161/CIRCIMAGING.118.008659DOI Listing
December 2019
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Influenza B virus infection complicated by life-threatening pericarditis: a unique case-report and literature review.

BMC Infect Dis 2019 Jan 10;19(1):40. Epub 2019 Jan 10.

Unit of Clinical Laboratory Science, University Campus Bio-Medico of Rome, Via Alvaro del Portillo, 200, Rome, Italy.

Background: Acute pericarditis may occur frequently after viral infections. To our knowledge, influenza B virus infection complicated by pericarditis without myocardial involvement has never been reported. We report the first case of life-threatening pericarditis caused by influenza B virus infection. Read More

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https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12879-018-3606-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327550PMC
January 2019
6 Reads

Grisel syndrome presenting as hemiplegia in a patient with multifocal sepsis.

Malawi Med J 2018 06;30(2):127-131

Consultant Trauma and Orthopaedic Surgeon; Dean of Faculty of Medicine, College of Medicine, University of Malawi.

Introduction: Grisel syndrome is a non-traumatic rotary subluxation of C1 on C2 (atlantoaxial subluxation). It is a rare condition predominantly described in paediatric population with previous history of upper respiratory infections orotolaryngeal procedures. The diagnosis is established by the association of clinical and radiologic findings4,6. Read More

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http://dx.doi.org/10.4314/mmj.v30i2.13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307069PMC
June 2018
2 Reads

A Case of IgG4-related Pericarditis in which Oral Corticosteroid Therapy was Effective.

Intern Med 2019 Jan 10. Epub 2019 Jan 10.

Division of Internal Medicine, Nerima-Hikarigaoka Hospital, Japan.

IgG4-related diseases (IgG4-RDs) have recently been reported in many organs other than the salivary, pancreatic and hepatobiliary systems. A 64-year-old woman was referred to our department for her abdominal fullness and cardiomegaly on chest X-ray. After draining the pericardial fluid, her symptom promptly diminished, and pericardial friction rubbing became clearly audible. Read More

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http://dx.doi.org/10.2169/internalmedicine.1403-18DOI Listing
January 2019
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Cardiac Evaluation in the Acute Phase of Chagas' Disease with Post-Treatment Evolution in Patients Attended in the State of Amazonas, Brazil.

Arq Bras Cardiol 2019 Jan 7. Epub 2019 Jan 7.

Universidade do Estado do Amazonas, Manaus, AM - Brazil.

Background: In the past two decades, a new epidemiological profile of Chagas' disease (CD) has been registered in the Brazilian Amazon where oral transmission has been indicated as responsible for the increase of acute cases. In the Amazonas state, five outbreaks of acute CD have been registered since 2004. The cardiac manifestations in these cases may be characterized by diffuse myocarditis, with alteration in the electrocardiogram (ECG) and transthoracic echocardiogram (TTE). Read More

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http://dx.doi.org/10.5935/abc.20190007DOI Listing
January 2019
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The Time Course of Radiation-induced Lung Injury in a Nonhuman Primate Model of Partial-body Irradiation With Minimal Bone Marrow Sparing: Clinical and Radiographic Evidence and the Effect of Neupogen Administration.

Health Phys 2019 Mar;116(3):366-382

Statistician, Rockville, MD.

The primary objectives of two companion manuscripts were to assess the natural history of delayed radiation-induced lung injury in a nonhuman primate model of acute high-dose, partial-body irradiation with 5% bone marrow sparing, to include the clinical, radiographic, and histopathological evidence and the effect of Neupogen administration on the morbidity and mortality. Nonhuman primates were exposed to 10.0 or 11. Read More

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http://dx.doi.org/10.1097/HP.0000000000000968DOI Listing
March 2019
2 Reads
0.774 Impact Factor

Acute Influenza Infection Presenting with Cardiac Tamponade: A Case Report and Review of Literature.

Perm J 2019 ;23

Department of Pulmonary and Critical Care, University of Arkansas for Medical Sciences Medical Center, Little Rock.

Introduction: Cardiac complications associated with influenza infection can occur either via a direct effect of the virus on the heart or through exacerbation of preexisting cardiovascular disease. We present a case of a 57-year-old man with acute influenza infection complicated by pericardial effusion and cardiac tamponade.

Case Presentation: A 57-year-old white man presented to the Emergency Department with sudden onset of severe, nonexertional, retrosternal, pressure-like chest pain for a few hours and with fever and muscle aches for 2 days. Read More

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http://dx.doi.org/10.7812/TPP/18-104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326557PMC
January 2019
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Quantitative assessment of pericardial delayed hyperenhancement helps identify patients with ongoing recurrences of pericarditis.

Open Heart 2018 16;5(2):e000944. Epub 2018 Dec 16.

Department of Cardiovascular Imaging, Center for the Diagnosis and Treatment of Pericardial Diseases, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA.

Objectives: Recurrences of pericarditis (RP) are often difficult to diagnose due to lack of clinical signs and symptoms during subsequent episodes. We aimed to investigate the value of quantitative assessment of pericardial delayed hyperenhancement (DHE) in diagnosing ongoing recurrences of pericarditis.

Methods: Quantitative DHE was measured in 200 patients with established diagnosis of RP using cardiac MRI. Read More

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http://openheart.bmj.com/lookup/doi/10.1136/openhrt-2018-000
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http://dx.doi.org/10.1136/openhrt-2018-000944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307595PMC
December 2018
6 Reads

When Chest Pain Reveals More: A Case of Hydrochlorothiazide-Induced Systemic Lupus Erythematosus.

Am J Case Rep 2019 Jan 7;20:26-30. Epub 2019 Jan 7.

Department of Internal Medicine, Trihealth Good Samaritan Hospital, Cincinnati, OH, USA.

BACKGROUND Drug induced lupus erythematosus is considered an autoimmune entity which is precipitated by medications. Hydrochlorothiazide has been recognized to cause subacute cutaneous lupus erythematosus, but very few cases of systemic drug induced lupus systemic erythematosus have been reported. CASE REPORT A 57-year-old Caucasian male with a past medical history of hypertension and hyperlipidemia presented with recurrent fevers, chest pain, and dyspnea. Read More

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http://dx.doi.org/10.12659/AJCR.911380DOI Listing
January 2019
2 Reads