953 results match your criteria Perianal Abscess


A 30-year trend analysis in the epidemiology of inflammatory bowel disease in the Songpa-Kangdong District of Seoul, Korea in 1986-2015.

J Crohns Colitis 2019 Apr 16. Epub 2019 Apr 16.

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background And Aims: Although the incidence of inflammatory bowel disease (IBD) is increasing in Asia, data on long-term epidemiologic trends are limited. We performed a 30-year longitudinal study to investigate temporal trends in the epidemiology of Crohn's disease (CD) and ulcerative colitis (UC) in Seoul, Korea.

Methods: This population-based study included 1431 IBD patients (418 CD, 1013 UC) diagnosed between 1986 and 2015 in the Songpa-Kangdong district of Seoul, Korea. Read More

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http://dx.doi.org/10.1093/ecco-jcc/jjz081DOI Listing

Rectal Endoscopic Ultrasound in Clinical Practice.

Curr Gastroenterol Rep 2019 Apr 12;21(4):18. Epub 2019 Apr 12.

Division of Gastroenterology, Washington University School of Medicine, 660 South Euclid Ave., Campus Box 8124, Saint Louis, MO, 63110, USA.

Purpose Of Review: Endoscopic ultrasound (EUS) is routinely utilized for evaluation of disorders of the lower gastrointestinal tract. In this review, we summarize the current status of rectal EUS in clinical practice and describe recent developments in diagnostic and therapeutic rectal EUS.

Recent Findings: Recent guidelines recommend rectal EUS for rectal cancer staging as a second line modality in cases where MRI is contraindicated. Read More

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http://dx.doi.org/10.1007/s11894-019-0682-9DOI Listing

A 53-Year-Old Man Presenting With Diplopia and Cavitary Lung Nodules.

Chest 2019 Apr;155(4):e107-e112

Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.

Case Presentation: A 53-year-old Chinese man presented with 1 week of worsening diplopia and left-sided facial droop. His symptoms developed during a readmission for elective drainage and curettage of a perianal abscess that recurred despite drainage 2 weeks before. He denied having other neurologic symptoms, and did not report any cough, sputum production, night sweats, or fever. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00123692183260
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http://dx.doi.org/10.1016/j.chest.2018.10.021DOI Listing
April 2019
3 Reads
7.483 Impact Factor

Online training on how to diagnose anoperineal lesions of Crohn's disease: Do pictures matter? A nationwide randomized study.

Clin Res Hepatol Gastroenterol 2019 Mar 29. Epub 2019 Mar 29.

Philippe-Marteau, université Paris Sorbonne, AP-HP, pole digestif, hôpital Saint Antoine 75012 Paris, France. Electronic address:

Any gastroenterologist must be trained to properly diagnose anoperineal lesions in patients with Crohn's disease (APLOC). The aim of this study was to establish whether adding pictures would improve teaching effectiveness of the diagnosis of APLOC to French gastroenterology trainees.

Method: Trainees were asked to answer a first web-based survey consisting of evaluating 12 pictures of APLOC with a closed answer questionnaire. Read More

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http://dx.doi.org/10.1016/j.clinre.2018.12.003DOI Listing
March 2019
1 Read

Epidemiology and outcomes of anal abscess in patients on chronic dialysis: a 14-year retrospective study.

Clinics (Sao Paulo) 2019 Mar 21;74:e638. Epub 2019 Mar 21.

Department of Nephrology, Kidney Research Center, Linkou Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan.

Objectives: We conducted this retrospective study to elucidate the clinical presentation and outcomes of anal abscess in chronic dialysis patients.

Methods: We performed a chart review of patients who were hospitalized for anal abscess from Jan. 2002 to Dec. Read More

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http://dx.doi.org/10.6061/clinics/2019/e638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438129PMC
March 2019
2 Reads

The Role of Familial Mediterranean Fever Gene Mutation in Treatment of Infantile Colitis With Resistant Perianal Fistula.

Arch Rheumatol 2018 Dec 23;33(4):473-477. Epub 2018 Mar 23.

Department of Pediatric Surgery, Ege University School of Medicine, İzmir, Turkey.

Symptoms of infantile inflammatory bowel disease (I-IBD) can be life-threatening and associated with poor prognosis. The presence of Mediterranean fever (MEFV) gene mutations play an important role in treatment of I-IBD. In this article, we describe a case of I-IBD with a resistant fistula, in which remission occurred following colchicine therapy. Read More

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https://www.archivesofrheumatology.org/full-text/1014
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http://dx.doi.org/10.5606/ArchRheumatol.2018.6741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409165PMC
December 2018
4 Reads

Mean Platelet Volume as an Inflammation Marker Reflecting the Severity of Perianal Abscesses.

Clin Lab 2019 Mar;65(3)

Background: A perianal abscess (PA) is a common disease in colorectal surgery practice. The mean platelet volume (MPV) is a parameter, which reflects the activation of platelets. The present study determined the relationship between PAs and MPV. Read More

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http://dx.doi.org/10.7754/Clin.Lab.2018.180627DOI Listing

Hyperimmunoglobulinemia D syndrome with recurrent perianal abscess successfully treated with canakinumab.

Scott Med J 2019 Mar 12:36933019836405. Epub 2019 Mar 12.

5 Professor, Department of Pediatric Rheumatology, Cukurova University Faculty of Medicine, Turkey.

Hyperimmunoglobulinaemia D syndrome is an autoinflammatory disease usually representing recurrent episodes of fever, arthralgia/arthritis, cervical lymphadenopathy, vomiting, diarrhoea, abdominal pain and skin rashes lasting 3-7 days every 4-8 weeks since their infancy. Recent reports suggested a link between perianal fistulae/abscess and severe colitis with hyperimmunoglobulinaemia D syndrome resembling an inflammatory bowel disease phenotype. Herein, we report an 18-month-old patient with recurrent attacks of fever and pharyngitis lasting 2-3 days every 10-15 days since the first two weeks of life. Read More

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http://dx.doi.org/10.1177/0036933019836405DOI Listing
March 2019
3 Reads

The Limited Utility of Routine Culture in Pediatric Pilonidal, Gluteal, and Perianal Abscesses.

J Surg Res 2019 Mar 6;239:208-215. Epub 2019 Mar 6.

Department of Surgery, Section of Pediatric Surgery at Yale University, New Haven, Connecticut. Electronic address:

Background: Pilonidal, buttock, and perianal abscesses are common reasons for surgical consultation in the pediatric emergency department. Treatment typically includes a bedside incision and drainage, often followed by an abscess culture, and a course of oral antibiotics. We aimed to study the impact of culture data on changes in management and clinical outcomes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00224804193009
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http://dx.doi.org/10.1016/j.jss.2019.02.017DOI Listing
March 2019
6 Reads

A Rare Case of Crohn's Disease Manifesting as a Large Liver Abscess.

Cureus 2018 Dec 21;10(12):e3758. Epub 2018 Dec 21.

Internal Medicine, Florida Hospital, Orlando, USA.

Liver abscess is a rare complication seen in Crohn's disease (CD) and has been rarely reported. Our aim is to illustrate a case of liver abscess in a patient with CD and the importance of a complete history and physical examination in identifying the potential cause of a hepatic abscess in an immune competent individual in who the diagnosis of CD was apparently ignored for two years before she presented to us. Although the manifestation of a hepatic abscess without any perianal abscess or fistula in CD is extremely rare, recognition of this would facilitate the diagnosis and appropriate management of abscess and CD. Read More

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http://dx.doi.org/10.7759/cureus.3758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389026PMC
December 2018
2 Reads

Malignant transformation of a chronic anorectal fistula.

Ann Ital Chir 2018 Oct 11;7. Epub 2018 Oct 11.

Up to date, only a small number of carcinomas arising from a chronic anorectal fistula have been described in medical literature, especially in patients without Chron's disease. A 72-year-old man with a 6-year history of discharging perianal sinus without Crohn's disease arrived at our institution. He had previously undergone three surgical procedures in other institutions for incision and drainage of recurrent perianal abscesses. Read More

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October 2018
3 Reads

Long-Term Outcomes of Ligation of the Inter-Sphincteric Fistula Tract Plus Bioprosthetic Anal Fistula Plug (LIFT-Plug) in the Treatment of Trans-Sphincteric Perianal Fistula.

Med Sci Monit 2019 Feb 20;25:1350-1354. Epub 2019 Feb 20.

Department of General Surgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China (mainland).

BACKGROUND The ligation of the inter-sphincteric fistula tract plus bioprosthetic anal fistula plug (LIFT-plug) is a new procedure in the treatment of trans-sphincteric perianal fistulas. The aim of this study was to evaluate its long-term outcomes. MATERIAL AND METHODS Clinical data of 78 patients with trans-sphincteric perianal fistula who were managed by the LIFT-plug technique between March 2014 to October 2016 were analyzed retrospectively. Read More

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http://dx.doi.org/10.12659/MSM.914925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391857PMC
February 2019
2 Reads

Antibiotic use in prevention of anal fistulas following incision and drainage of anorectal abscesses: A systematic review and meta-analysis.

Am J Surg 2019 Jan 31. Epub 2019 Jan 31.

Centre for the Advancement of Minimally Invasive Surgery (CAMIS), Royal Alexandra Hospital, Edmonton, Alberta, Canada. Electronic address:

Background: Treatment of anorectal abscesses continues to revolve around early surgical drainage and control of perianal sepsis. Yet even with prompt drainage, abscess recurrence and postoperative fistula formation rates are as high as 40% within 12 months. These complications are thought to be associated with inadequate drainage, elevated bacterial load, or a noncryptoglandular etiology of disease. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2019.01.015DOI Listing
January 2019
8 Reads

A Validated Score Assessing the Risk for an Intra-Abdominal Abscess in Patients with Crohn's Disease Presenting at the Emergency Department.

J Crohns Colitis 2019 Feb 14. Epub 2019 Feb 14.

Institute of Gastroenterology and Liver Diseases, Department of Medicine, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.

Background And Aims: A majority of acutely-ill Crohn's disease (CD) patients who present to Emergency Department (ED) will undergo an abdominal CT to rule out disease complications. We aimed to generate a simple non-invasive scoring model to predict the presence of an intra-abdominal abscess in CD patients in the ED.

Methods: We performed a retrospective case control study at four Israeli hospitals from January-1 st-2010 to May-30 th-2018. Read More

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http://dx.doi.org/10.1093/ecco-jcc/jjz043DOI Listing
February 2019
1 Read

[A Case of Rectal Cancer Presenting with Perianal Abscess].

Gan To Kagaku Ryoho 2019 Jan;46(1):88-90

Dept. of Surgery, Yao Tokushukai General Hospital.

An 81-year old man with a perirectal abscess was referred in May 2017 by another hospital. We observed swelling in the anal region at the 4 o'clock position and performed incisional drainage. Although this alleviated the pain and inflammation in the anal region, the irritation recurred in early June. Read More

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January 2019
1 Read

Differentiation between intestinal Behçet’s disease and Crohn’sdisease based on endoscopy

Turk J Med Sci 2019 Feb 11;49(1):42-49. Epub 2019 Feb 11.

Background/aim: Differentiating intestinal Behçet’s disease (BD) from Crohn’s disease (CD) is highly challenging, as they often mimic each other in terms of clinical manifestations. Endoscopy is an important modality for distinguishing bowel lesions. The study was designed to identify clinical manifestations that are easily confused and to evaluate the efficacy of endoscopy for distinguishing intestinal BD from CD by several overlapping signs. Read More

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http://dx.doi.org/10.3906/sag-1807-67DOI Listing
February 2019
1 Read

One stage fistulectomy for high anal fistula with reconstruction of anal sphincter without fecal diversion.

Asian J Surg 2019 Feb 6. Epub 2019 Feb 6.

General surgery department, Cairo University, Egypt.

Perianal sepsis and fistula is a troublesome disease in the field of colorectal surgery in term of recurrence and fecal incontinence. The aim of our study is to evaluate the role of 'one stage complex anal fistula excision with reconstruction of anal sphincter without stool diversion' regarding fecal incontinence and recurrence. This was prospective cohort study on 175 patients of complex high peri-anal fistulae, the patients were subjected to fistulectomy and reconstruction (primary suture repair) of anal sphincter without stool diversion, the patients were followed up 1 year postoperatively after complete healing of the wound regarding their continence to stool and gases using Wexner score and recurrence of the fistula which is examined clinically and radio-logically using MRI. Read More

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http://dx.doi.org/10.1016/j.asjsur.2018.12.005DOI Listing
February 2019
1 Read

EFSUMB Recommendations for Gastrointestinal Ultrasound Part 3: Endorectal, Endoanal and Perineal Ultrasound.

Ultrasound Int Open 2019 Jan 5;5(1):E34-E51. Epub 2019 Feb 5.

Department of Surgery, Haukeland University Hospital and Department of Clinical Medicine, University of Bergen, Bergen, Norway.

This article represents part 3 of the EFSUMB Recommendations and Guidelines for Gastrointestinal Ultrasound (GIUS). It provides an overview of the examination techniques recommended by experts in the field of endorectal/endoanal ultrasound (ERUS/EAUS), as well as perineal ultrasound (PNUS). The most important indications are rectal tumors and inflammatory diseases like fistula and abscesses in patients with or without inflammatory bowel disease (IBD). Read More

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http://dx.doi.org/10.1055/a-0825-6708DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363590PMC
January 2019
12 Reads

Recognizing Fournier's Gangrene in the Emergency Department.

Adv Emerg Nurs J 2019 Jan/Mar;41(1):33-38

Georgetown University, Washington, District of Columbia.

Fournier's gangrene is a rare disease with a significant mortality rate. The potentially fatal disease stems from both aerobic and anaerobic bacteria and primarily occurs in men. The majority of Fournier's gangrene cases are idiopathic or derived from perineal and genital skin infections. Read More

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http://dx.doi.org/10.1097/TME.0000000000000221DOI Listing
February 2019
3 Reads

Perianal abscess in a 2-year-old presenting with a febrile seizure and swelling of the perineum.

Oxf Med Case Reports 2019 Jan 24;2019(1):omy116. Epub 2019 Jan 24.

Emergency Medicine Physician, Beaumont Hospital, Teaching Hospital of Michigan State University, Department of Emergency Medicine, Farmington Hills, MI, USA.

An anorectal abscess, specifically a perianal abscess, is a relatively uncommon infection in children. It is a purulent fluid collection under the soft tissue outside the anus. Some of these abscesses may spontaneously drain and heal by themselves, while others may result in sepsis and require surgical intervention. Read More

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http://dx.doi.org/10.1093/omcr/omy116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345087PMC
January 2019

[Quality indicators in the treatment of anal fistulas].

Authors:
O Schwandner

Chirurg 2019 Apr;90(4):270-278

Abteilung für Proktologie, Krankenhaus Barmherzige Brüder Regensburg, Prüfeninger Str. 86, 93049, Regensburg, Deutschland.

Anal fistulas are a common anorectal disease and are frequently associated with a perianal abscess. The etiology is based on a cryptoglandular infection in the intersphincteric space. Surgery remains the only definitive therapy. Read More

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http://link.springer.com/10.1007/s00104-019-0794-7
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http://dx.doi.org/10.1007/s00104-019-0794-7DOI Listing
April 2019
9 Reads

Packing versus mushroom catheters following incision and drainage in anorectal abscess.

Ir J Med Sci 2019 Jan 23. Epub 2019 Jan 23.

Department of Surgery, Cork University Hospital, Wilton Road, Cork, Ireland.

Purpose: Management of anorectal abscess is traditionally by incision and drainage with packing. This study assessed the use of mushroom catheters compared with packing of anorectal abscess after incision and drainage in adults. Placement of a mushroom catheter to allow ongoing drainage of the cavity may have advantages by eliminating the need for painful dressing changes. Read More

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http://link.springer.com/10.1007/s11845-018-01958-6
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http://dx.doi.org/10.1007/s11845-018-01958-6DOI Listing
January 2019
31 Reads

Ambulatory Surgery for Perianal Crohn's Disease: Study of Feasibility.

Gastroenterol Res Pract 2018 23;2018:5249087. Epub 2018 Dec 23.

Policlinico Tor Vergata, Department of Surgery, University Tor Vergata, Viale Oxford 81, 00133 Rome, Italy.

Background: One-third of Crohn's disease (CD) patients present perianal fistula. The gold standard in the diagnosis and treatment of symptomatic perianal disease (PAD) in CD is the exploration of the anal canal and distal rectum under anesthesia (EUA). This procedure is mainly conducted as a day case surgery. Read More

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http://dx.doi.org/10.1155/2018/5249087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323458PMC
December 2018
10 Reads

A rare presentation of infection: Perianal abscess associated with lumbar spine osteitis.

IDCases 2019 7;15:e00488. Epub 2019 Jan 7.

Department of Medicine, Hospital Pedro Hispano, Unidade Local de Saúde de Matosinhos, Rua Dr. Eduardo Torres, 4464-513, Matosinhos, Portugal.

is a ubiquitous, rapidly growing, gram-positive bacterium causing infections in humans and animals. It is responsible for a variety of symptoms depending on the infection site and the integrity of the host's immune system. Case reports of skin and soft tissues infections by Listeria are rare. Read More

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http://dx.doi.org/10.1016/j.idcr.2019.e00488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330363PMC
January 2019
2 Reads

A mini-invasive procedure for the treatment of supralevator abscess of cryptoglandular origin by extrasphincteric extension: preliminary results at 1-year follow-up.

Int J Colorectal Dis 2019 Apr 15;34(4):763-767. Epub 2019 Jan 15.

Department of Radiology, "S. Maria dei Battuti" Hospital, Via Brigata Bisagno 4, 31015, Conegliano, TV, Italy.

Aim: The aim of this retrospective study is to evaluate the preliminary results of a mini-invasive procedure for the treatment of supralevator abscesses (SLA) of cryptoglandular origin by extrasphincteric extension.

Method: In this clinical study, an innovative two-stage procedure was tested for the surgical treatment of SLA. As first step and as a preparation for surgery, the interventional radiologist positioned a CT-guided percutaneous perianal guidewire inside the abscess cavity under local anesthesia. Read More

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http://dx.doi.org/10.1007/s00384-019-03243-zDOI Listing
April 2019
3 Reads

First case in China of vaccine-associated poliomyelitis after sequential Inactivated and bivalent oral polio vaccination.

Vaccine 2019 Jan 7;37(5):751-754. Epub 2019 Jan 7.

School of Social Development and Public Policy, Beijing Normal University, China. Electronic address:

A 16 week newborn vaccinated with bOPV 4 weeks after his first routine IPV vaccination. Nineteen days later, asymmetrical paralysis was developed on his legs, and it was diagnosed to be VAPP. Perianal abscess is suspected to be a risk factor based on some limited results of retrospective studies in China. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X183169
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http://dx.doi.org/10.1016/j.vaccine.2018.12.022DOI Listing
January 2019
15 Reads

[Chinese experts consensus on diagnosis and treatment of non-perianal fistulating Crohn disease].

Authors:
Jianan Ren

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Dec;21(12):1337-1346

Surgeon Committee of Gastrointestinal Fistula of Chinese College of Surgeons, Email:

Crohn disease (CD) is a chronic inflammatory disease involving the entire digestive tract and non-perianal fistula is the most serious surgical complication of CD. The goal of treatment is to cure intestinal fistula and intra-abdominal infection, restore the continuity of digestive tract, reduce postoperative recurrence, and improve the quality of life. Evaluation of nutritional status, especially during perioperative period, is important and nutrition support for malnutritional CD patients is necessary. Read More

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December 2018
18 Reads

A Case Report of Basal Cell Carcinoma in a Non-Sun-Exposed Area: A Rare Presentation Mimicking Recurrent Perianal Abscess.

Case Rep Surg 2018 21;2018:9021289. Epub 2018 Nov 21.

Department of Surgery, Warren Alpert Medical School of Brown University, Providence, RI, USA.

Basal cell carcinoma (BCC), a common malignancy, arises most often in sun-exposed areas but does rarely occur in non-sun-exposed sites. Prior tissue injury, especially sharp trauma and chronic inflammation, increases the risk of BCC. We describe a 66-year-old male patient with recurrent perianal abscesses who was found to have a large pigmented basal cell carcinoma. Read More

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https://www.hindawi.com/journals/cris/2018/9021289/
Publisher Site
http://dx.doi.org/10.1155/2018/9021289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280225PMC
November 2018
3 Reads

A 10-Year Follow-up Study of the Natural History of Perianal Crohn's Disease in a Danish Population-Based Inception Cohort.

Inflamm Bowel Dis 2018 Dec 20. Epub 2018 Dec 20.

The Gastro Unit, Medical Division, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.

Background: Perianal complications in patients with Crohn's disease are common and have a negative impact on the patients' quality of life. Data about the long-term disease course of perianal Crohn's disease in the era of biological treatment are limited. In this population-based cohort study, we sought to investigate the occurrence, clinical risk factors, and disease course of perianal disease. Read More

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http://dx.doi.org/10.1093/ibd/izy374DOI Listing
December 2018
2 Reads

Red flags for appropriate referral to the gastroenterologist and the rheumatologist of patients with inflammatory bowel disease and spondyloarthritis.

Clin Exp Immunol 2019 Apr 9;196(1):123-138. Epub 2019 Jan 9.

IBD Unit, Presidio Columbus, Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, Rome, Italy.

Collaboration between gastroenterologists and rheumatologists is recommended for the correct management of patients with associated spondyloarthritis (SpA) and inflammatory bowel disease (IBD). We aimed to establish the appropriateness of several red flags for a prompt specialist referral. A systematic review of the literature was performed using the GRADE method to describe the prevalence of co-existing IBD-SpA and the diagnostic accuracy of red flags proposed by a steering committee. Read More

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http://dx.doi.org/10.1111/cei.13246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422654PMC
April 2019
9 Reads

The risk of inflammatory bowel disease in subjects presenting with perianal abscess: findings from the THIN database.

J Crohns Colitis 2018 Dec 13. Epub 2018 Dec 13.

Department of Gastroenterology, Sandwell and West Birmingham Hospitals NHS Trust, UK.

Background: Perianal abscess (PA) is associated with inflammatory bowel disease (IBD). The incidence of IBD after a diagnosis of PA and potential predictors of a future diagnosis of IBD are unknown.

Methods: The Health Improvement Network (THIN) is a primary care database representative of the UK population. Read More

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http://dx.doi.org/10.1093/ecco-jcc/jjy210DOI Listing
December 2018
11 Reads

Risk of postoperative morbidity in patients having bowel resection for colonic Crohn's disease.

Tech Coloproctol 2018 12 12;22(12):947-953. Epub 2018 Dec 12.

Department of Surgery, Ålborg University Hospital, Ålborg, Denmark.

Background: The aim of the present multicenter study was to analyze the incidence and risk factors associated with postoperative morbidity in patients who had colorectal resection for colonic Crohn's disease.

Methods: Consecutive patients undergoing colorectal resection for colonic Crohn's disease at seven surgical units in 1992-2017 were included. Exclusion criteria were: proctectomy for perianal disease, surgery for cancer, previous colectomies, surgery before 1998. Read More

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http://dx.doi.org/10.1007/s10151-018-1904-0DOI Listing
December 2018

Safety and Efficacy of Rituximab in Multiple Sclerosis: A Retrospective Observational Study.

J Immunol Res 2018 12;2018:9084759. Epub 2018 Nov 12.

Nehme and Therese Tohme Multiple Sclerosis Center, American University of Beirut Medical Center, Beirut, Lebanon.

Objective: To evaluate the efficacy and safety of rituximab in multiple sclerosis in a clinical practice setting.

Methods: Clinical data for all adult patients with multiple sclerosis (MS) treated with off-label rituximab at a single MS center in Lebanon between March 2008 and April 2017 were retrospectively collected from medical charts. The main efficacy outcomes assessed were annualized relapse rate (ARR) and proportion of patients free from relapses, disability progression, or magnetic resonance imaging (MRI) activity. Read More

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https://www.hindawi.com/journals/jir/2018/9084759/
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http://dx.doi.org/10.1155/2018/9084759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260423PMC
January 2019
6 Reads

Combined management of perianal rhabdomyosarcoma with chemotherapy, radical surgery, and irradiation: A series of three consecutive children.

J Pediatr Surg 2019 Feb 7;54(2):285-287. Epub 2018 Nov 7.

Children's Hospital, Section of Pediatric Surgery, University of Helsinki, Finland.

Background And Aim: We describe a series of three successive patients with perianal rhabdomyosarcoma (PRMS) from 2014 to 2017 managed with combined chemotherapy, radical surgery, and radiotherapy.

Methods: Ethical consent was obtained. Data including tumor presentation, treatment, and survival was collected from hospital reports. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.10.090DOI Listing
February 2019
1 Read

First aid toolkit for anal fistulas, a detailed treatise for trainees - a video vignette (ESCP Trainee Video).

Authors:
D D E Zimmerman

Colorectal Dis 2019 Feb 15;21(2):244. Epub 2018 Dec 15.

ETZ Hospital, Tilburg, The Netherlands.

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http://dx.doi.org/10.1111/codi.14496DOI Listing
February 2019
45 Reads

Treatment of perianal sepsis, a detailed treatise for trainees - a video vignette (ESCP Trainee Video).

Authors:
D D E Zimmerman

Colorectal Dis 2019 Feb 15;21(2):243. Epub 2018 Dec 15.

ETZ Hospital, Tilburg, the Netherlands.

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http://dx.doi.org/10.1111/codi.14495DOI Listing
February 2019
16 Reads

Factors Affecting Mortality in Fournier Gangrene: A Single Center Experience.

Surg Infect (Larchmt) 2019 Jan 7;20(1):78-82. Epub 2018 Nov 7.

Faculty of Medicine, Department of General Surgery, Kirikkale University , Kirikkale, Turkey .

Background: The objective of this study was to determine the clinical and laboratory features affecting mortality in Fournier gangrene.

Patients And Methods: This retrospective case control study was designed to evaluate patients treated for Fournier gangrene in our center between 2010 and 2018. Those patients were divided into two groups: discharged patients (group 1) and deceased patients (group 2). Read More

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https://www.liebertpub.com/doi/10.1089/sur.2018.208
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http://dx.doi.org/10.1089/sur.2018.208DOI Listing
January 2019
20 Reads

[Cheilitis granulomatosa revealing Crohn's disease].

Pan Afr Med J 2018 20;30:147. Epub 2018 Jun 20.

Service d'Hépato-gastroentérologie, Faculté de Médecine et de Pharmacie de Fès, Université Sidi Mohammed Ben Abdellah, Fès, Maroc.

Many disorders of the digestive tract cause cutaneous manifestations that may be an indication of an underlying condition; hence dermatologist plays a key role in recommending that the patient see a gastroenterologist. Conversely, gastroenterologist often sees patients with mucocutaneous lesions suggesting possible association with well-known digestive disorders. Chronic inflammatory bowel diseases are the typical example of this essential collaboration between the two specialities. Read More

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http://dx.doi.org/10.11604/pamj.2018.30.147.5395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201612PMC
November 2018
8 Reads

Role of interleukin-17 in the pathogenesis of perianal abscess and anal fistula: a clinical study on 50 patients with perianal abscess.

ANZ J Surg 2019 Mar 25;89(3):244-247. Epub 2018 Oct 25.

Department of Colorectal and Anal Surgery, Jinhua Municipal Central Hospital, Jinhua, China.

Background: To investigate the role of interleukin (IL)-17 in tissue and peripheral blood of perianal abscess and anal fistula.

Methods: Patients with primary perianal abscess (n = 50) admitted to Jinhua Municipal Central Hospital between March 2003 and August 2004 were enrolled. Fifty patients with mixed haemorrhoids, who showed no perianal abscess or anal fistula, were also recruited as the control. Read More

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http://doi.wiley.com/10.1111/ans.14874
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http://dx.doi.org/10.1111/ans.14874DOI Listing
March 2019
5 Reads

Horseshoe abscess: Perianal and giant abdominal abscess.

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:81

Department of Radiology, Concord Repatriation General Hospital, Concord, New South Wales, Australia.

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http://dx.doi.org/10.1111/1754-9485.29_12784DOI Listing
October 2018
2 Reads

Identifying Outcomes in Clinical Trials of Fistulizing Crohn's Disease for the Development of a Core Outcome Set.

Clin Gastroenterol Hepatol 2018 Oct 4. Epub 2018 Oct 4.

Robarts Clinical Trials, Inc, London, Ontario, Canada; Department of Medicine, Western University, London, Ontario, Canada; Department of Epidemiology and Biostatistics, Western University, London, Ontario, Canada. Electronic address:

Fistulizing complications develop in approximately one third of patients with Crohn's disease (CD), resulting in morbidity and impaired quality of life. Sites of fistulae most commonly include perianal fistulae, but also enterocutaneous, enteroenteric, enterovesical, and rectovaginal. Its management requires combined medical and surgical strategies to prevent abscess formation and induce healing. Read More

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http://dx.doi.org/10.1016/j.cgh.2018.10.004DOI Listing
October 2018
3 Reads

The contribution of preoperative MRI to the surgical management of anal fistulas.

Diagn Interv Radiol 2018 Nov;24(6):321-327

Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.

Purpose: Anal fistula is an abnormal tract or cavity between the anal canal and perianal skin. Surgical treatment of anal fistulas requires the identification of the course of the primary and secondary tracts and their relation with the sphincter musculature in order to appropriately manage them and drain any abscess. Physical examination alone is not as accurate as imaging modalities in detecting these features of the fistula, and recurrences are usually due to missed or inadequately managed infective components. Read More

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http://www.dirjournal.org/eng/makale/1942/62/Full-Text
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http://dx.doi.org/10.5152/dir.2018.18340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6223824PMC
November 2018
20 Reads

Retrospective Clinical and Microbiologic Analysis of Patients with Anorectal Abscess.

Surg Infect (Larchmt) 2019 Jan 20;20(1):31-34. Epub 2018 Sep 20.

3 Department of Microbiology, Faculty of Medicine, Kuwait University , Jabriya, Kuwait .

Background: We conducted a clinical and microbiologic analysis of patients presenting with anorectal abscess.

Methods: A total of 505 adult patients presenting from January 2011 to December 2017 were analyzed retrospectively. Microbiologic data were available for 211 patients. Read More

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http://dx.doi.org/10.1089/sur.2018.144DOI Listing
January 2019
3 Reads

Fournier gangrene due to Rhizobium Radiobacter.

Pak J Med Sci 2018 Jul-Aug;34(4):1027-1029

Mehmet Oguz Sahin, M.D. Department of Urology, Manisa State Hospital, Manisa, Turkey.

Fournier's gangrene (FG) is a life-threatening, rapidly progressing acute necrotizing fasciitis of perianal, genitourinary and perineal areas. The most common isolated pathogens are , and in tissue and abscess cultures. However we present the first Rhizobium radiobacter FG in this case. Read More

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http://pjms.com.pk/index.php/pjms/article/view/14489
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http://dx.doi.org/10.12669/pjms.344.14489DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6115549PMC
September 2018
9 Reads

[What's new in the treatment of suppurative hidradenitis in 2018 ?]

Rev Med Liege 2018 Sep;73(9):468-473

Service de Dermatologie,CHU Sart Tilman, Liège, Belgique.

Hidradenitis suppurativa (HS), also known as Verneuil's disease and acne inversa, is a chronic inflammatory skin disease characterized by a dysfunction of the pilosebaceous structures resulting in occlusion and inflammation. The disease usually starts after puberty, on average between twenty and thirty years, with subcutaneous painful inflammatory nodules, abscess collections, fistulization and scars mainly in the axillary, inguinal, sub-mammary, perineal and perianal regions. It is a multifactorial disease with the most commonly cited risk factors or aggravating factors being smoking, obesity, and HS family history. Read More

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September 2018
2 Reads

Constipation, failure to thrive and recurrent abscesses: getting to the bottom of an unusual complaint.

Arch Dis Child Educ Pract Ed 2018 Sep 3. Epub 2018 Sep 3.

Department of Paediatric Education and Simulation, Royal Belfast Hospital for Sick Children, Belfast, UK.

QUESTION 1: Which procedure may have been most appropriate to offer an initial clue to her diagnosis? Abdominal X-ray. Digital rectal examination. Perianal swab for streptococcal infection. Read More

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http://ep.bmj.com/lookup/doi/10.1136/archdischild-2018-31531
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http://dx.doi.org/10.1136/archdischild-2018-315317DOI Listing
September 2018
7 Reads

Perianal Infections in Children With Acute Myeloid Leukemia: A Report From the Canadian Infection in Acute Myeloid Leukemia Research Group.

J Pediatric Infect Dis Soc 2018 Aug 24. Epub 2018 Aug 24.

Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada.

Among 235 children with acute myeloid leukemia, 17 experienced 19 perianal infections. Among 12 episodes with definite abscess, 75% were severely neutropenic. Sixteen diagnostic imaging evaluations were performed; diagnostic yield was similar between computerized tomography of pelvis (5 of 10) and ultrasound (3 of 5). Read More

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http://dx.doi.org/10.1093/jpids/piy081DOI Listing
August 2018
20 Reads

Significant Medical and Surgical Morbidity in Perianal Crohn's Disease: Results from a Territory-Wide Study.

J Crohns Colitis 2018 Nov;12(12):1392-1398

Department of Medicine and Therapeutics, Institute of Digestive Disease, State Key Laboratory of Digestive Disease, LKS Institute of Health Science, The Chinese University of Hong Kong, Hong Kong.

Background: The presence of perianal fistulas in Crohn's disease [CD] denotes increased disease aggressiveness. We studied the epidemiology and clinical outcomes of perianal CD [PCD] using the Hong Kong territory-wide IBD Registry [HKIBDR].

Methods: Consecutive patients with PCD were identified from the HKIBDR, and disease characteristics, treatments, and outcomes were analysed. Read More

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http://dx.doi.org/10.1093/ecco-jcc/jjy120DOI Listing
November 2018
18 Reads

Contrast- vs. non-contrast enhanced MR data sets for characterization of perianal fistulas.

Abdom Radiol (NY) 2019 Feb;44(2):446-455

Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, White 270, Boston, MA, 02114, USA.

Purpose: To evaluate the diagnostic efficacy between pre- and post-contrast MRI sequences in perianal fistulas using intra-operative findings as the gold standard.

Materials And Methods: Retrospective analysis of 50 patients with a history of perianal fistula and MRI performed between January 2006 and January 2018 was performed. The inclusion criteria were patients who underwent MRI prior to surgery and had a detailed surgical report available. Read More

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http://dx.doi.org/10.1007/s00261-018-1761-3DOI Listing
February 2019
19 Reads