82 results match your criteria Perforating Folliculitis
Clin Exp Dermatol 2018 May 19. Epub 2018 May 19.
Department of Dermatology, Saint Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
Int J Trichology 2018 Mar-Apr;10(2):89-91
Department of Dermatology, Jorhat Medical College and Hospital, Jorhat, Assam, India.
Cutaneous adverse effects of chemotherapy are widely known but underreported. A significant advancement is made in the field of oncology with the advent of new classes of drug being added to the existing classes at a fast pace. Most of these cutaneous adverse effects are self-limiting and subsides on suspending the drug either temporarily or permanently. Read More
Indian Dermatol Online J 2018 Jan-Feb;9(1):20-26
Department of Dermatology, Venereology and Leprosy, Dr. R. P. Govt. Medical College, Kangra, Himachal Pradesh, India.
Background: Chronic kidney disease (CKD)-associated mucocutaneous manifestations significantly impair the quality of life but often remain understudied. They may also vary across regions, socioeconomic and nutritional status, and racial differences.
Objectives: To study the patterns of mucocutaneous disorders and their prevalence in CKD patients irrespective of clinical stage or dialysis status. Read More
Indian Dermatol Online J 2017 Jul-Aug;8(4):290-292
Department of Dermatology and Pathology, St. Johns Medical College, Bengaluru, Karnataka, India.
An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):10-13
Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Rio de Janeiro (RJ), Brazil.
Perforating dermatoses are a group of skin diseases characterized by transepidermal elimination of dermal material. The disease is divided into two groups: the primary group and the secondary group. The classical or primary perforating dermatoses are subdivided into four types according to the eliminated dermal materials: Kyrle disease, perforating reactive collagenosis, elastosis perforans serpiginosa, and perforating folliculitis. Read More
Dermatol Ther (Heidelb) 2016 Dec 9;6(4):471-507. Epub 2016 Sep 9.
Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.
Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. Read More
G Ital Dermatol Venereol 2015 Oct 18;150(5):533-46. Epub 2015 Jun 18.
Department of Experimental and Clinical Medicine Institute of Dermatology University of Udine, Udine, Italy -
Beside to traditional use, dermoscopy is more and more used in the assessment of other "general" dermatologic conditions, namely scalp and hair disorders (trichoscopy), nails abnormalities (onychoscopy), skin infections and infestations (entomodermoscopy), and cutaneous inflammatory diseases (inflammoscopy). Among the list of new applications of dermoscopy, the study of inflammatory dermatoses is probably the most promising topic in terms of development and usefulness, considering the large number of such disorders and the frequent problems in their differential diagnosis which the dermatologist encounters in own daily clinical practice. In this paper, we report selected relatively common clinical differential diagnosis issues concerning inflammatory dermatoses (and some clinically related noninflammatory conditions), analysing them by a dermoscopic point of view in order to assist their noninvasive resolution according to the available literature data and our personal experience, including papulosquamous dermatoses (guttate psoriasis, pityriasis lichenoides chronica, pityriasis rosea, lichen planus, lymphomatoid papulosis, classic pityriasis rubra pilaris, papulosquamous sarcoidosis, disseminated forms of porokeratosis and papulosquamous chronic GVHD), dermatoses presenting with erythematous-desquamative patches/plaques (plaque psoriasis, eczematous dermatitis, pityriasis rosea, mycosis fungoides, subacute cutaneous lupus erythematosus), palmar psoriasis vs. Read More
J Biol Regul Homeost Agents 2015 Jan-Mar;29(1 Suppl):95-8
Onkoderma-Clinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria.
Perforating folliculitis (PF) describes the process by which altered dermal material is eliminated from the epidermis through a follicular unit resulting in keratotic, follicular papules that favor hair-bearing regions of the forearms, arms, buttocks, and thighs. Diabetes mellitus (DM) and chronic renal failure (CRF) are commonly associated with PF. The more general term, acquired perforating dermatosis, has been applied to PF as well as Kyrles disease and the non-inherited form of perforating collagenosis. Read More
Br J Dermatol 2015 Aug 19;173(2):618-20. Epub 2015 Jun 19.
Department of Dermatology, Reference Centre for Cutaneous Adverse Drug Reactions, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Australas J Dermatol 2014 Aug;55(3):233-5
Department of Dermatology, Hospital Álvarez-Buylla, Mieres, Spain.
Ann Dermatol 2014 Apr 30;26(2):162-71. Epub 2014 Apr 30.
Department of Dermatology, Eulji General Hospital, Eulji University, Seoul, Korea.
Background: Acquired perforating dermatosis (APD) is histopathologically characterized by transepidermal elimination of materials from the upper dermis. APD can be divided into four diseases: Kyrle's disease, perforating folliculitis, elastosis perforans serpiginosa, and reactive perforating collagenosis. APD is usually associated with systemic diseases, especially diabetes mellitus or chronic renal failure. Read More
Cutis 2014 Jan;93(1):E8-10
Skin and Allergy Hospital, HUS, PO Box 160, Helsinki, Finland 00029.
Eur J Dermatol 2013 Nov-Dec;23(6):864-71
Background: Acquired perforating dermatosis (APD) is a rare group of skin disorders characterized by transepidermal elimination of dermal tissue material. There are only a few studies of APD.
Objective: We aimed to review the clinicopathologic features of patients with APD and evaluate the outcomes of treatments. Read More
Indian J Pathol Microbiol 2013 Oct-Dec;56(4):355-8
Department of pathology, K. J. Somaiya Medical College and Research Centre, Mumbai, Maharashtra, India.
Background: Perforating disorders of the skin, is an often overlooked entity characterized by transepidermal elimination of material from the upper dermis and are classified histopathologically according to the type of epidermal disruption and the nature of the eliminated material. They include Kyrle's disease, perforating folliculitis, reactive perforating collagenosis, and elastosis perforans serpiginosa.
Aim: The aim of this study was to delineate the clinical and histopathological features of perforating disorders of the skin. Read More
J Cutan Pathol 2013 Oct;40(10):859-62
Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
Dermatol Online J 2013 Jul 14;19(7):18958. Epub 2013 Jul 14.
Center for Clinical Studies, 1401 Binz St., Houston, TX 77004, USA.
Acquired Perforating Dermatosis (APD) is a perforating disease characterized by transepidermal elimination of dermal material [1,2]. This disease usually develops in adulthood. APD has been reported to occur in association with various diseases, but is most commonly associated with dialysis-dependent chronic renal failure (CRF) or diabetes mellitus (DM) [1,2,3,4]. Read More
Am J Dermatopathol 2014 Jul;36(7):592-3
*Contrato Río Hortega del ISCIII, Fundación de Investigación De La Princesa, Madrid, Spain; Departments of †Hematology, ‡Dermatology, §Pathology, Hospital Universitario de La Princesa, Madrid, Spain; ‖Department of Dermatology, Fundación Jimenez Diaz, Madrid, Spain.
We present a case of perforating folliculitis in a patient treated with nilotinib, a kinase inhibitor. A 48-year-old man presented with a severely pruritic follicular rash for several months that started after reaching a complete molecular response of his myeloid chronic while treated with nilotinib. Clinical examination showed predominantly follicular pinpoint papules on trunk and proximal extremities and a biopsy showed a slightly dilated hair follicle with a focal disruption of the infundibular follicular epithelium. Read More
Am J Dermatopathol 2013 Oct;35(7):757-60
*Department of Pathology and Laboratory Medicine, and †Division of Dermatology, University of Kansas Medical Center, Kansas City, KS ‡Department of Pathology, SUNY Upstate Medical University, Syracuse, NY.
: Necrotizing infundibular crystalline folliculitis (NICF) is a rare entity manifesting as waxy folliculocentric papules comprised of filamentous birefringent crystalline deposits. We report a case of NICF in an 85-year-old man, presenting as gritty, cream-colored, and erythematous papules across the midline back. Biopsy demonstrated a pale plug comprised of copious mucin. Read More
Ann Dermatol Venereol 2012 Jun 30;139(6-7):481-5. Epub 2012 May 30.
Service de dermatologie, hôpital central de l'Armée Ain Naadja (HCA), Kouba 16000 Alger, Algérie. salhi
Background: Reactive perforating collagenosis (RPC) belongs to the group of perforating dermatoses, which comprises elastosis perforans serpiginosa, RPC, perforating folliculitis and Kyrle's disease. RPC was initially described as a distinctive form of transepithelial elimination of altered collagen related to superficial trauma. Two types are distinguished: a hereditary type (MIM 216700), which is rare and begins during early childhood, and a second type, called acquired RPC, which is more frequent, appears in adults and is associated with other diseases, diabetes mellitus, renal insufficiency, solid tumors, lymphomas and AIDS. Read More
Vet Dermatol 2012 Apr 7;23(2):136-44, e30. Epub 2012 Feb 7.
Department of Pathobiology, University of Guelph, Ontario, Canada.
A rare congenital dermatosis, characterized by progressive hypotrichosis with variable scaling and crusting, occurred in 10 short-haired kittens in North America and Europe. Lesions appeared at between 4 and 12 weeks of age, commencing on the head and becoming generalized. The tail was spared in two kittens. Read More
Pediatr Dermatol 2010 Nov-Dec;27(6):660-1
Department of Dermatology, Case Medical Center, Case Western Reserve University/University Hospitals, Lakeside 3500, 11100 Euclid Avenue, Cleveland, OH 44106, USA.
We report a case of a young man with perforating folliculitis and cystic fibrosis with complications including chronic obstructive pulmonary disease, insulin dependent diabetes mellitus, and liver cirrhosis. We demonstrate increased TGF-β1 immunohistochemical staining in the perforating folliculitis lesions of our patient and discuss the possible associations between cystic fibrosis and perforating folliculitis. Read More
J Dermatol 2010 Sep;37(9):833-4
Eur J Dermatol 2010 May-Jun;20(3):364-6. Epub 2010 Feb 22.
Department of Dermatology, University of Cologne, Kerpener Str. 62, 50937 Cologne, Germany.
Perforating folliculitis is characterized by asymptomatic skin-coloured or erythematous scattered and aggregated follicular papules with a central keratotic plug. Histologically, a superficial type can be distinguished from the profound type where perforations and rupture of the follicular wall take place at different levels of the hair follicle. This goes along with a granulomatous reaction of the entire pilary complex with destruction of the follicle epithelium and sebaceous gland. Read More
Cesk Patol 2009 Jul;45(3):75-8
Ustav patologickej anatómie, Jesseniova lekárska fakulta v Martine, Univerzita Komenského v Bratislave.
A 26-year-old woman suddenly noticed an onset of disseminated papular exanthema during her institutional treatment for alcohol abuse. After 9 weeks of slowly progressive course a dermatologist was consulted, who suggested a diagnosis of pityriasis lichenoides. Skin biopsy revealed cystical enlargement of hair follicles that were filled up with keratinous and parakeratotic masses interspersed with particles of fragmented collagen. Read More
J Dtsch Dermatol Ges 2009 May 29;7(5):449-52. Epub 2009 Jan 29.
Donauspital SMZ Ost, Department of Dermatology and Venereology, Vienna, Austria.
A patient with clear cell renal cell carcinoma was treated with sorafenib, a multikinase inhibitor, which induced a variety of cutaneous side effects. In addition to xerosis, he developed angioedema (AE), hand-foot syndrome (HFS) and perforating folliculitis (PF). The latter three occurred in a dose-dependent manner. Read More
Clin Exp Dermatol 2008 Aug 8;33(5):653-4. Epub 2008 Jul 8.
Br J Dermatol 2007 Feb;156(2):368-71
Deapartment of Dermatology, San Jorge General Hospital, Huesca, Spain.
Perforating dermatoses are characterized by transepithelial elimination of dermal structures. We report a 61-year-old man with rheumatoid arthritis who developed a perforating folliculitis following the administration of two tumour necrosis factor (TNF)-alpha inhibitors, infliximab and etanercept. To our knowledge, no perforating disorders have been reported associated with these drugs. Read More
Vet Dermatol 2006 Dec;17(6):432-9
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, USA.
In this report we describe the historical, clinical, histopathological and microbiological features, as well as treatments and clinical outcome, of pyoderma where Pseudomonas aeruginosa alone was isolated on bacterial culture from lesional skin. Twenty dogs were included in this retrospective study. Seven dogs without prior history of systemic or skin disease presented with acute deep pseudomonal pyoderma characterized by a sudden onset of dorsal truncal pain. Read More
J Eur Acad Dermatol Venereol 2006 Jul;20(6):679-88
Başkent University Faculty of Medicine, Department of Dermatology, Ankara, Turkey.
Background: The term of acquired perforating dermatosis (APD) comprises the perforating dermatoses occurring in adult patients. Clinical and histological features of the disease are not uniform, and may resemble any of the four classic perforating disorders: elastosis perforans serpiginosa, reactive perforating collagenosis, perforating folliculitis or Kyrle's disease. Chronic renal failure and/or diabetes mellitus usually accompany this skin disease. Read More
Vnitr Lek 2006 May;52(5):454-8
Klinika nemocí kozních a pohlavních Lékarské fakulty UK a FN, Hradec Krĺové.
Even a half of diabetic patients are suffering from skin troubles. Hyperglykemia causes skin changes leading to higher incidence of bacterial and mycotic infections, provokes skin degenerative processes, macro- and microangiopathy and neuropathy. Diabetic dermopathy, rubeosis, bullousis and scleredema are based on these changes. Read More
Presse Med 2006 Mar;35(3 Pt 1):399-406
Service de Dermatologie, CHU Hédi Chaker, Sfax, Tunisie.
Objective: Chronic hemodialysis patients experience frequent and varied cutaneous manifestations, of often hypothetical pathogenesis. The aim of this work is to assess the prevalence and nature of these cutaneous lesions and discuss some pathogenic mechanisms.
Methods: This prospective study was conducted from 1 February through 30 April 1996. Read More
Dermatol Ther 2005 Jul-Aug;18(4):344-54
Department of Dermatology, Henry Ford Hospital, Detroit, Michigan 48202, USA.
Ultraviolet-based therapy has been used to treat various pruritic conditions including pruritus in chronic renal failure, atopic dermatitis, HIV, aquagenic pruritus and urticaria, solar, chronic, and idiopathic urticaria, urticaria pigmentosa, polycythemia vera, pruritic folliculitis of pregnancy, breast carcinoma skin infiltration, Hodgkin's lymphoma, chronic liver disease, and acquired perforating dermatosis, among others. Various mechanisms of action for phototherapy have been posited. Treatment limitations, side effects, and common dosing protocols are reviewed. Read More
Int J Dermatol 2005 Mar;44(3):210-4
Department of Dermatology, Kyungpook National University Hospital, Daegu 700-721, Korea.
Background: Perforating disorders are uncommon diseases characterized by transepidermal elimination histopathologically and include reactive perforating collagenosis, elastosis perforans serpiginosa, Kyrle's disease and perforating folliculitis. In addition, perforating disorders can develop in patients with diabetes mellitus, renal failure and even by accidental exposure of calcium salts.
Methods: We report two cases of perforating disorder caused by chemical burn with commercially available salt-water application for self-treatment of chronic dermatitis or pruritus. Read More
Br J Dermatol 2004 Mar;150(3):614-6
Eur J Dermatol 2003 Nov-Dec;13(6):592
Department of Dermatology, Military Medical Academy, Belgrade, Serbia.
Nephrol Nurs J 2002 Dec;29(6):525-7, 531-9; quiz 540-1
University of Tennessee Health Science Center, USA.
Cutaneous manifestations occurring in patients with end stage renal disease (ESRD) can indicate systemic problems that have significant morbidity and mortality risks. Skin changes are sometimes a consequence of the disease that caused the renal failure or may be an ESRD manifestation. Pruritus is the most prevalent ESRD cutaneous complaint, but its pathogenesis is not understood. Read More
Med Pregl 2002 Jan-Feb;55(1-2):47-50
Klinika za kozno-venericne bolesti, Klinicki centar, Novi Sad.
Introduction: Hyperkeratosis follicularis et parafollicularis in cuten penetrans known as Kyrle's disease is a recessive hereditary genodermatosis. Generally, Kyrle's disease appears between 30 to 50 years of age and women are affected more than men.
Case Report: We report a case of a 40-year-old man, a worker in a cement factory, who noticed the first skin lesions six years ago. Read More
Br J Dermatol 2002 Jan;146(1):74-9
Department of Dermatology, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Background: Perforating skin dermatoses include elastosis perforans serpiginosa (EPS), reactive perforating collagenosis, Kyrle's disease and perforating folliculitis. In addition to these four diseases, an acquired form of perforating dermatosis associated with diabetes mellitus and/or chronic renal failure has been reported for which the term acquired perforating dermatosis (APD) was proposed. The molecular mechanism of transepidermal elimination of dermal components in perforating skin dermatoses remains unclear. Read More
Br J Dermatol 2001 Jul;145(1):165-8
Skin and Cancer Foundation Australia, 277 Bourke Street, Darlinghurst, NSW 2010, Australia.
We describe a 22-year-old woman with a background of acne who developed multiple folliculocentric facial papules associated with sharply demarcated waxy, keratotic plugs. Multiple skin biopsies showed umbilicated craters that were filled with dispersed bundles of eosinophilic filaments embedded in a pale amorphous matrix forming a plug. The plugs bulged into the upper dermis. Read More
Dtsch Med Wochenschr 1999 Mar;124(10):282-4
Hautklinik, Friedrich-Schiller-Universität Jena.
History And Admission Findings: A 70-year-old woman with type 2B diabetes mellitus was referred to the dermatology department because of inflammatory skin changes of unknown origin over the trunk and limbs. On admission follicular and parafollicular livid-red papulae with central crusts and reddened margins were noted over the lower legs and the lumbosacral region.
Investigations: Further physical examination revealed no additional abnormalities. Read More
Hautarzt 1999 Feb;50(2):115-20
Klinik und Poliklinik für Dermatologie, Universitätsklinikum Benjamin Franklin, Hindenburgdamm, Berlin.
Perforating disorders represent a heterogenous group of dermatoses characterized by transepithelial elimination of dermal structures. Primary perforating disorders should be distinguished from secondary perforating disorders in which perforation with transepithelial elimination is a rare component of a variety of dermatoses. The primary perforating disorders are hyperkeratosis follicularis et parafollicularis in cutem penetrans (Kyrle's disease), elastosis perforans serpiginosa and perforating folliculitis. Read More
J Am Acad Dermatol 1999 Feb;40(2 Pt 2):300-2
Department of Dermatology, La Paz University Hospital, Madrid, Spain.
Am J Dermatopathol 1998 Apr;20(2):147-54
Department of Pathology: University of South Florida Health Science Center, James A. Haley Veteran's Hospital, Tampa, USA.
Despite detailed microscopic descriptions and clinical observation, little is known regarding the pathogenesis of the perforating disorders of skin, which have traditionally been subdivided into numerous microscopic entities associated with various clinical settings. An increasing body of evidence now suggests that the perforating disorders of skin are akin, and may constitute an expanded single pathologic entity. Each of the classic perforating disorders of skin, including elastosis perforans serpiginosa, perforating folliculitis, reactive perforating collagenosis, Kyrle's disease, and perforating disorder of uremia, have been shown to extrude collagen, elastin, and related extracellular matrix components through the epidermis. Read More
Nephron 1997 ;77(1):48-56
Department of Medicine, Federal University of Santa Catarina, Florianopolis, Brazil.
Two dialysis patients with markedly elevated plasma silicon (Si) levels (3,849 and 2,350 micrograms/l, respectively) and a presumed Si-related syndrome are described in this report. One patient presented with transient hypercalcemia in the face of low PTH, vitamin D and plasma A1 levels. Both patients had painful, nodular skin eruptions and aberrant hair growth, characterized as perforating folliculitis on skin biopsy, compatible with known effects of organosilicon compounds in man and animals. Read More
Ther Umsch 1995 Apr;52(4):230-5
Dermatologische Klinik, Universitätsspital Zürich.
Skin symptoms in renal disease occur in a series of rare inherited or acquired diseases affecting the kidneys as well as the skin (amyloidosis, vasculitis, angiokeratoma diffusum corporis Fabry) (table 1). Chronic renal failure, regardless of its origin, often causes important skin symptoms, such as pruritus, the typical complexion with elastosis seen in uremic patients, porphyria cutanea uremica, metastatic calcifications, skin necrosis due to uremic small arteries disease with medial calcification and intimal hyperplasia, perforating dermatoses, nail lesions and symptoms of the oral mucosa (table 2). The following article reviews the pathogenesis and the limited possibilities of treatment for skin symptoms in chronic renal failure. Read More
Am J Dermatopathol 1994 Oct;16(5):474-85
Department of Dermatology, Faculty of Medicine, University of Stellenbosch, Tygerberg, Republic of South Africa.
We report 10 women and five men with papulonecrotic tuberculid, an uncommon form of cutaneous tuberculosis (TB). The mean age was 22.6 years (range, 2 1/2-35 years) at presentation. Read More
Int J Dermatol 1993 Dec;32(12):874-6
Department of Dermatology, Guatemalan Social Security Institute, General Hospital, Central America.
Background: A study of nine Guatemalan patients with acquired perforating disease associated with chronic renal failure, diagnosed at the Guatemalan Social Security Institute, General Hospital, during the period of January 1990 to March 1993, is presented (Table 1).
Methods: A dermatological examination and skin biopsy were done on all patients.
Results: Six of the patients were men and three were women; one case was associated with diabetes mellitus. Read More
J Dermatol 1993 Jun;20(6):329-40
Department of Dermatology, Lady hardinge Medical College and Associated S.K. & K.S.C. Hospitals, New Delhi, India.
Perforating dermatoses, an often overlooked entity comprised of Kyrle's disease, perforating folliculitis, reactive perforating collagenosis, elastosis perforans serpiginosa, and acquired perforating dermatosis, are succinctly described, focusing attention on their clinical features, histopathology, treatment, and pathogenesis. The literature on these facets has been extensively reviewed. In addition, three fresh cases of Kyrle's and one of perforating folliculitis have been incorporated to illustrate these conditions. Read More
Ann Dermatol Venereol 1990 ;117(8):515-20
Clinique Dermatologique, Hôpital d'Instruction des Armées Desgenettes, Lyon.
We report the case of a 20-year old male patient without significant familial or personal history who presented with a disseminated papular eruption on the abdomen, flanks and buttocks. The eruption was continual and proceeded by outbreaks, but it was not influenced by seasons. Physical examination of the skin, mucosae and skin appendages was otherwise normal. Read More