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Zhongguo Gu Shang 2022 May;35(5):423-9

Department of Orthopaedics, the Second Affiliated Hospital of Chengdu Medical College, China National Nuclear Corporation 416 Hospital, Chengdu 610000, Sichuan, China.

Objective: To investigate the effects of different bone cement morphology distribution on the clinical efficacy of unilateral percutaneous vertebroplasty(PVP) for spinal osteoporotic fractures.

Methods: The clinical data of 66 patients with osteoporotic vertebral compression fractures received unilateral PVP treatment from January 2019 to April 2020 were retrospectively analyzed. There were 16 males and 50 females, including 83 vertebral bodies, 45 thoracic vertebrae and 38 lumbar vertebrae, and 55 patients with single-segment, 6 double-segment, 4 three-segment and 1 four-segment. Read More

Zhongguo Gu Shang 2022 May;35(5):418-22

Department of Orthopaedics, Union Hospital Affiliated to Fujian Medical University, Fuzhou 350001, Fujian, China.

Objective: To analyze the efficacy of percutaneous vertebroplasty for osteoporotic vertebral compression fractures with spinal origin abdominal pain as the main symptom.

Methods: A retrospective analysis was performed on 37 patients with osteoporotic vertebral compression fractures treated from January 2015 to January 2021, all of whom had spin-derived abdominal pain as the main symptom, and were divided into surgery group(21 cases) and conservative group (16 cases) according to different treatment methods. Patients in the surgery group were treated with percutaneous vertebroplasty, including 7 males and 14 females, with an average age of (75. Read More

Geriatr Orthop Surg Rehabil 2022 3;13:21514593221098620. Epub 2022 May 3.

Department of Endoscopic Diagnosis, Daqing Oilfield General Hospital, Daqing, China.

Purpose: New vertebral compression fractures(NVCFs) after minimally invasive surgery in patients with osteoporotic vertebral compression fracture (OVCF) is a challenging issue worldwide. Predicting the occurrence of NVCFs is key to addressing such questions. Therefore, we aimed to investigate the risk factors for patients who developed NVCFs after undergoing surgical treatment and establish a nomogram model to reduce the occurrence of NVCFs. Read More

Ann Med 2022 12;54(1):1320-1327

Department of Physical Therapy, College of Medicine, National Cheng Kung University, Tainan City 701 Taiwan.

Vertebral compression fractures (VCFs) often occur in patients with osteoporosis. These fractures can also lead to postural changes. Several studies have shown that patients with vertebral compression fractures have a restrictive pattern in their pulmonary function. Read More

Asian J Surg 2022 Apr 30. Epub 2022 Apr 30.

Affiliated Xiaolan Hospital, Southern Medical University, Orthopaedics Department, No. 65, Jucheng Rd., Xiaolan Dist., 528415, Zhongshan, Guangdong Prov, PR China. Electronic address:

J Int Med Res 2022 Apr;50(4):3000605221096161

Department of Orthopaedic Surgery, People's Hospital of Yichun City, Jiangxi Province, P.R. China.

Waldenstrom's macroglobulinemia (WM) is a rare type of malignant B-cell lymphoma. The main feature of WM is elevated serum monoclonal immunoglobulin M, similar to multiple myeloma (MM). Unlike in MM, the rarity of destructive bone lesions in WM has been repeatedly emphasized. Read More

J Pain Res 2022 21;15:1173-1182. Epub 2022 Apr 21.

Department of Diagnostic and Interventional Radiology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, People's Republic of China.

Objective: To evaluate the feasibility, safety, and efficacy of vessel-plasty using bone-filling mesh container (BFMC) for malignant severe compression fractures of cervical vertebra.

Methods: This study prospectively recruited fifteen consecutive patients (eight men, seven women; mean age, 57.4 years) with severe malignant compression fractures of cervical vertebrae for vessel-plasty. Read More

Int J Surg 2022 Apr 20;101:106632. Epub 2022 Apr 20.

Department of Orthopedics, Beijing Friendship Hospital Capital Medical University, No.95, Yong'an Road, Xicheng District, Beijing, 100050, China. Electronic address:

Background: Pulmonary cement embolism (PCE) was a rare but fatal complication for percutaneous vertebral augmentation (PVA). Thus we did a systematic review and meta-analysis of cohort studies to investigate the risk factors for PCE after PVA.

Methods: We systematically searched PubMed, EMBASE, Cochrane library, Google Scholar, web of science, and ClinicalTrial. Read More

Medicine (Baltimore) 2022 Mar 11;101(10):e29034. Epub 2022 Mar 11.

Department of Orthopedics, Taizhou Traditional Chinese Medicine Hospital, Zhejiang, China.

Background: There is currently no pooled data in the literature to support whether additional facet joint block results in better clinical analgesia after percutaneous kyphoplasty. We assessed the existing evidence on the safety and efficacy of facet joint block in the treatment of patients with thoracolumbar compression fractures undergoing percutaneous kyphoplasty based on qualified trials.

Methods: We will search PubMed, Springer, ScienceDirect, Wanfang, and Cochrane Library databases through April, 2022. Read More

Medicine (Baltimore) 2022 Mar 11;101(10):e29011. Epub 2022 Mar 11.

Department of Anesthesia Institute, HangZhou Hospital of Traditional Chinese Medical. No. 453 Tiyuchang Road, Hangzhou, Zhejiang Province, China.

Abstract: To evaluate the feasibility, efficacy, and safety of minimally invasive pedicle screw (MIPS) fixation, including the fractured vertebra, combined with percutaneous vertebroplasty (PVP) for the treatment of acute thoracolumbar osteoporotic compression fracture in middle-age and elderly individuals.Between January 2016 and August 2019, a total of 30 patients, with a mean age of 69.4 years (range, 58-75 years), who experienced thoracic or lumbar fracture without neurological deficits, underwent the MIPS procedure combined with PVP. Read More

AJNR Am J Neuroradiol 2022 May 21;43(5):776-783. Epub 2022 Apr 21.

From the Department of Neuroradiology (A.C., R.L.D., M.I., M.P.).

Background And Purpose: Fractures with "vertebra plana" morphology are characterized by severe vertebral body collapse and segmental kyphosis; there is no established treatment standard for these fractures. Vertebroplasty and balloon kyphoplasty might represent an undertreatment, but surgical stabilization is challenging in an often elderly osteoporotic population. This study assessed the feasibility, clinical outcome, and radiologic outcome of the stent screw-assisted internal fixation technique using a percutaneous implant of vertebral body stents and cement-augmented pedicle screws in patients with non-neoplastic vertebra plana fractures. Read More

Eur Radiol 2022 Apr 21. Epub 2022 Apr 21.

Department of Neuroradiology, Pitié-Salpêtrière Hospital, APHP, Sorbonne University, 47 boulevard de l'Hôpital, 75013, Paris, France.

Objectives: Cement leakages in soft tissues are a common occurrence during cementoplasty. They may cause chronic pain, and thus treatment failure. Spindle malposition during reinforced cementoplasty may cause vascular, nerve or cartilage injury. Read More

J Spine Surg 2022 Mar;8(1):70-75

Division of Orthopedics, Department of Surgery, University of Montreal Health Center, Montreal, QC, Canada.

Vertebroplasty is a minimally invasive treatment option for osteolytic spinal lesions. It provides pain relief and stability with established good results. In this paper, we describe a new CT guided percutaneous vertebroplasty technique using a direct lateral approach between the carotid sheath and the vertebral artery, that can be safely performed under conscious sedation in an outpatient setting. Read More

BMC Musculoskelet Disord 2022 Apr 13;23(1):356. Epub 2022 Apr 13.

Orthopaedic Surgery Department, Spine Unit; Pitié-Salpétrière Hospital, 47-83 bd de l'hôpital, 75013, Paris, France.

Background: The restauration of the local kyphosis is crucial to thoracolumbar fractures outcomes. Recently, the Tektona™ (Spine Art) system, constituted by a flexible lamella for corporeal reduction has emerged as a promising solution for osteoporotic fractures. However, no study has yet focused on its results on traumatic fractures. Read More

BMC Musculoskelet Disord 2022 Apr 11;23(1):343. Epub 2022 Apr 11.

Department of Orthopedics, The First Medical Center of PLA General Hospital, No. 28 Fuxing Road, Beijing, 100853, P. R. China.

Background: To explore the risk factors involved in the induction of thoracolumbar fascia (TLF) injury by osteoporotic vertebral compression fracture (OVCF), and the association between the residual pain after percutaneous vertebroplasty (PVP) and fascial injury.

Methods: A total of 81 patients with single-segment OVCF, treated between January 2018 and January 2020 were included. The patients were grouped according to the existence of TLF injury. Read More

Rev Esp Cir Ortop Traumatol 2022 Mar-Apr;66(2):T86-T94. Epub 2022 Feb 26.

Unidad de Raquis, Servicio de Cirugía Ortopédica y Traumatología, Hospital Clínico Universitario, Valencia, Spain.

Introduction And Objective: The incidence of osteoporotic vertebral fractures (OVFs) is increasing. The importance of their diagnosis and treatment lies in their frequency and the morbidity they cause in patients. The classification proposed for OVFs by the German Society of Orthopaedics and Traumatology (DGOU) recommends surgical treatment for vertebral fractures classified as OF4. Read More

Rev Esp Cir Ortop Traumatol 2022 Mar-Apr;66(2):86-94. Epub 2021 Nov 19.

Unidad de Raquis, Servicio de Cirugía Ortopédica y Traumatología, Hospital Clínico Universitario, Valencia, España.

Introduction And Objective: The incidence of osteoporotic vertebral fractures (OVF) is increasing. The importance of their diagnosis and treatment lies in their frequency and the morbidity they cause in patients. The classification proposed for OVFs by the German Society of Orthopaedics and Traumatology (DGOU) recommends surgical treatment for vertebral fractures classified as OF4. Read More

Front Surg 2022 25;9:769102. Epub 2022 Mar 25.

Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Objective: Although various studies have described the methods of administering anesthesia during percutaneous vertebroplasty (PV) for treating osteoporotic vertebral compression fractures (OVCFs), there is still no consensus on the optimal treatment regimen. Therefore, this study aimed to investigate the effects of three application methods of local analgesia administration in PV for treating OVCFs.

Methods: A total of 96 patients with OVCFs were reviewed and divided into three groups (A: lidocaine, B: ropivacaine, C: lidocaine + ropivacaine). Read More

Front Surg 2021 25;8:663099. Epub 2022 Mar 25.

Department of Orthopedics and Traumatology, Nantong Hospital of Traditional Chinese Medicine, Affiliated Traditional Chinese Medicine Hospital of Nantong University, Nantong, China.

Objective: To compare and analyze the therapeutic effect of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) combined with triple therapy on elderly patients with mild to moderate osteoporotic vertebral compression fractures (OVCF).

Methods: A total of 114 cases of elderly patients with mild to moderate osteoporotic vertebral compression fractures were identified as research subjects in our hospital from January 2017 to January 2018, and a total of 136 vertebrae were included. The patients who underwent PVP operation were included as the control group with 67 injured vertebrae, and the patients who underwent PKP operation were included as the experimental group with 69 injured vertebrae. Read More

Breast 2022 Jun 2;63:149-156. Epub 2022 Apr 2.

UCSF Helen Diller Family Comprehensive Cancer Center, San Francisco, CA, USA. Electronic address:

Patients with metastatic breast cancer are at high risk for developing vertebral compression fractures due to underlying bone metastases and bone density loss. Vertebral augmentation techniques including percutaneous vertebroplasty and percutaneous balloon kyphoplasty are techniques used to stabilize compression fractures and improve pain. However, rare complications from these interventions have been observed, including spinal cord compression, nerve root compression, venous cement embolism, and pulmonary cement embolism. Read More

World J Surg Oncol 2022 Apr 7;20(1):112. Epub 2022 Apr 7.

Department of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, People's Republic of China.

Objective: The objective of this research was to investigate the risk factors of cement leakage in patients with metastatic spine tumors following percutaneous vertebroplasty (PVP).

Methods: Sixty-four patients with 113 vertebrae were retrospectively reviewed. Various clinical indexes, including age, sex, body mass index (BMI), smoking history, drinking history, chemotherapy history, radiotherapy history, primary cancer, location, other metastases, collapse, posterior wall defects, the laterality of injection, and the injected cement volume were analyzed as potential risk factors. Read More

J Cancer Res Ther 2021 Dec;17(7):1725-1729

Department of Radiology, Ruijin Hospital, Luwan Branch, Shanghai Jiao Tong University School of Medicine; Department of Interventional Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.

Objective And Aims: To assess percutaneous vesselplasty's safety and efficacy in treating pathological vertebral compression fractures (VCFs).

Subjects And Methods: This retrospective review covered nine patients with an equal number of symptomatic pathological VCFs treated with vesselplasty. The study assessed the patients' pain scores, subjective conditions, imaging guidance, and incidence of procedure-related complications. Read More

J Orthop Surg Res 2022 Apr 4;17(1):202. Epub 2022 Apr 4.

Department of Orthopeadic, Huadong Hospital Affiliated to Fudan University, Shanghai, 200040, China.

Introduction: Percutaneous vertebroplasty (PVP) was recently performed for treating patients with osteoporotic vertebral compression fractures (OVCF). However, recompression of cemented vertebra with significant vertebral height loss occurred in the patients after PVP was observed during the follow-up period. The purpose is to explore the risk factors among several potential predictors for the height loss of treated vertebral bodies after PVP in patients with OVCF. Read More

Med Sci Monit 2022 Mar 28;28:e935080. Epub 2022 Mar 28.

Department of Orthopedic Surgery, Shijiazhuang People's Hospital, Shijiazhuang, Hebei, China (mainland).

BACKGROUND Cement leakage is the most common complication following percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) for osteoporotic vertebral compression fractures (OVCFs). Dynamic fracture mobility was determined by comparing preoperative standing lateral radiographs with intraoperative prone lateral radiographs. This retrospective study from a single center aimed to evaluate the effect of dynamic fracture mobility on cement leakage in PVP and PKP in 286 patients with OVCFs. Read More

Global Spine J 2022 Mar 26:21925682221087600. Epub 2022 Mar 26.

Department of Orthopaedics and Beijing Key Laboratory of Spinal Disease Research, 66482Peking University Third HospitalUniversity, Beijing, China.

Study Design: Retrospective Cohort Study.

Objectives: To describe surgeries and treatment outcomes of metastatic pheochromocytomas and paragangliomas (PPGLs) on the spine.

Methods: We reviewed a cohort of 18 patients with spinal PPGLs who were consecutively treated in our spinal center. Read More

Cureus 2022 Feb 8;14(2):e22006. Epub 2022 Feb 8.

Neurosurgery, University of Miami Hospital, Miami, USA.

This is a retrospective study that evaluated surgical versus non-surgical treatment of 100 patients followed for up to six years diagnosed with severe osteoporotic vertebral compression fractures (VCF). Fractures were classified by percent collapse of vertebral body height as "high-degree fractures" (HDF) (>50%) or vertebra plana (VP) (>70%). A total of 310 patients with VCF were reviewed, identifying 110 severe fractures in 100 patients. Read More

Cardiovasc Intervent Radiol 2022 May;45(5):720

Department of Diagnostic and Interventional Radiology, Nice University Hospital, Hôpital Pasteur 2, Nice, France.

J Orthop Surg Res 2022 Mar 12;17(1):161. Epub 2022 Mar 12.

Department of Orthopedics, Fuzong Clinical Medical College of Fujian Medical University, Fuzhou, 350025, Fujian, China.

Objective: Percutaneous vertebroplasty (PVP) and kyphoplasty (PKP) have been widely used to treat osteoporotic vertebral compression fractures (OVCF), but the risk of vertebral re-fracture after PVP/PKP remains controversial. This study aims to investigate the incidence and risk factors of vertebral re-fracture after PVP/PKP.

Methods: Relevant literatures published up to November 2021 were collected from PubMed, Embase and Web of Science. Read More

Pain Res Manag 2022 27;2022:3489160. Epub 2022 Feb 27.

Department of Emergency Medicine, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.

Objective: The present study investigated the clinical efficacy of percutaneous kyphoplasty (PKP) combined with calcitriol and calcium in the treatment of traumatic nonosteoporotic vertebral compression fractures (TNVCFs).

Methods: The patients were equally divided into a control group and a treatment group by a random number table. The patients in the control group underwent PKP surgery, and the patients in the treatment group received calcitriol and calcium on the basis of PKP surgery. Read More

Spine J 2022 Mar 5. Epub 2022 Mar 5.

Department Medical Imaging, Toronto Western Hospital, University Health Network, Toronto, Ontario Canada. Electronic address:

Background Context: Osteoporotic vertebral fractures (OVF) dramatically increase with age and are serious life altering adverse events for seniors resulting in increased rates of institutionalization, morbidity and mortality. Given the expanding population of the elderly and increasing prevalence of OVFs, cost-effective treatment strategies need to be considered. Percutaneous vertebral augmentation (VA) procedures such as vertebroplasty (VP) or balloon kyphoplasty (BK) are increasingly employed to treat painful vertebral fractures not responding to conservative management (CM) of bedrest and analgesia. Read More