Search Our Scientific Publications & Authors

Kardiologiia 2019 Apr 18;59(4):92-96. Epub 2019 Apr 18.

Central Clinical Hospital of the Management Affair of President RF, Moscow.

The article presents a clinical case of embolism with bone cement of the right ventricle of the heart and pulmonary artery after percutaneous vertebroplasty in a patient aged 63 years. According to the results of a comprehensive examination using ultrasound and x-ray methods, three foreign bodies were found: in the right ventricle cavity, in the trunk of the pulmonary artery, in the branches of the left pulmonary artery. Considering the stable condition, normal blood oxygen saturation, the lack of influence of formations on intracardiac hemodynamics, it was decided to refrain from surgery, since the risk of intervention exceeded the possible benefit. Read More

Cardiovasc Intervent Radiol 2019 Apr 2. Epub 2019 Apr 2.

Departments of Radiology and Internal Medicine, Elisabeth TweeSteden Hospital, Hilvarenbeekseweg 60, 5022 GC, Tilburg, The Netherlands.

Background: Percutaneous vertebroplasty (PV) is an alternative option to treat pain after an osteoporotic vertebral compression fracture (OVCF). Controversy exists as to whether PV increases the risk of new OVCFs or prevents further vertebral height loss in treated levels. We assessed both during 1-year follow-up in patients with acute OVCF randomised to PV or a sham procedure. Read More

Cancers (Basel) 2019 Mar 29;11(4). Epub 2019 Mar 29.

Main Regional Center for Cancer Pain and Supportive/Palliative Care, Anesthesia and Intensive Care Unit, and Pain Relief and Palliative Care Unit, La Maddalena Cancer Center, 90145 Palermo, Italy.

Interventional techniques to manage cancer-related pain may be efficient treatment modalities in patients unresponsive or unable to tolerate systemic opioids. However, indication and selection of the right technique demand knowledge, which is still incipient among clinicians. The present article summarizes the current evidence regarding the five most essential groups of interventional techniques to treat cancer-related pain: Neuraxial analgesia, minimally invasive procedures for vertebral pain, sympathetic blocks for abdominal cancer pain, peripheral nerve blocks, and percutaneous cordotomy. Read More

J Clin Neurosci 2019 Mar 25. Epub 2019 Mar 25.

Department of Neurosurgery, Johns Hopkins University School of Medicine, 600 N. Wolfe Street, Meyer Building 7-109, Baltimore, MD 21287, United States.

Metastatic disease to the spine are becoming increasingly common with an aging population and improvements in systemic cancer therapies. Surgery, radiation, and vertebroplasty are mainstay modalities for treating painful spine metastases. Recently, image-guided percutaneous ablation techniques have emerged a promising therapeutic option. Read More

Pain Physician 2019 03;22(2):177-185

Tallahassee Orthopedic Clinic, Tallahassee, FL.

Background: Vertebral compression fractures (VCFs) can be conservatively treated with pain management, bracing, and bed rest, or treated surgically with a kyphoplasty or vertebroplasty procedure.

Objectives: The objective of this retrospective review was to assess the viability, safety, and efficacy of using local anesthesia with oral sedation for an office-based kyphoplasty procedure.

Study Design: A retrospective review. Read More

Medicine (Baltimore) 2019 Mar;98(12):e14941

Department of Orthopedic, Shaanxi Provincial People's Hospital.

The aim of this study was to investigate the influence of vertebral bone mineral density (BMD) on total diffusion volume of bone cement in percutaneous vertebroplasty (PVP). This study was a retrospective review of prospectively collected data of consecutive patients with A1.2 thoracolumbar compression fractures treated by PVP. Read More

J Int Med Res 2019 Mar 17:300060519835084. Epub 2019 Mar 17.

Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Percutaneous vertebroplasty (PVP) is a minimally invasive treatment that has been widely used for the treatment of osteoporotic vertebral compression fractures and vertebral tumors. However, the maximum number of vertebral segments treated in a single PVP remains controversial. Furthermore, PVP may cause complications, including cement leakage, pulmonary embolism, bone cement toxicity, and spinal nerve-puncture injury. Read More

Ned Tijdschr Geneeskd 2019 Mar 11;163. Epub 2019 Mar 11.

Spaarne Gasthuis, afd. Radiologie, Haarlem/Hoofddorp.

We describe a 59-year-old woman, who came to the Emergency Room with fever, dyspnoea and lung abnormalities on chest x-ray. The X-ray abnormalities were not related to the clinical symptoms and could be explained by the patient's medical history, which included rib fractures and spinal compression fractures. The confined spherical structures visible on chest X-ray were indicative of previous rib fractures. Read More

Int J Comput Assist Radiol Surg 2019 Mar 12. Epub 2019 Mar 12.

Computer Aided Medical Procedures, Johns Hopkins University, Baltimore, MD, USA.

Purpose: As the trend toward minimally invasive and percutaneous interventions continues, the importance of appropriate surgical data visualization becomes more evident. Ineffective interventional data display techniques that yield poor ergonomics that hinder hand-eye coordination, and therefore promote frustration which can compromise on-task performance up to adverse outcome. A very common example of ineffective visualization is monitors attached to the base of mobile C-arm X-ray systems. Read More

J Forensic Leg Med 2019 Apr 5;63:48-51. Epub 2019 Mar 5.

Department of Legal Medicine, Azienda USL Toscana Nordovest, Lucca, Italy.

Percutaneous vertebroplasty consists of percutaneous injection of polymethylmethacrylate (PMMA) via a transpedicular approach for the treatment of collapsed osteoporotic or metastatic vertebrae. Even if percutaneous vertebroplasty is considered to be minimally invasive, threatening complications can occur. Cement leakage is the most common complication of percutaneous vertebroplasty. Read More

Medicine (Baltimore) 2019 Mar;98(10):e14793

Department of Orthopedics, Zhongshan City Torch High-tech Industrial Development Zone Hospital, Torch High-tech Industrial Development Zone, Zhongshan City, Guangdong Province.

To compare percutaneous vertebroplasty (VP) and balloon kyphoplasty (BKP) for their effectiveness and safety in the treatment of newly onset osteoporotic vertebral compression fractures (VCF).Patients with confirmed diagnosis of newly onset osteoporotic VCF and treated in our center between January 2008 and December 2016 were retrospectively included in the study. Patients were divided into 2 groups according the surgical treatment they have received. Read More

PLoS One 2019 5;14(3):e0213164. Epub 2019 Mar 5.

Department of Spinal Surgery, General Hospital of Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, China.

To observe the regional anatomy of the lumbar artery (LA) associated with the extrapedicular approach applied during percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP), we collected 78 samples of abdominal computed tomography angiography imaging data. We measured the nearest distance from the center of the vertebral body puncture point to the LA (distance VBPP-LA, DVBPP-LA). According to the DVBPP-LA, four zones, Zone I, Zone II, Zone III and Zone IV, were identified. Read More

Spine J 2019 Feb 26. Epub 2019 Feb 26.

Center for Spine Surgery & Research, Middelfart Hospital, Østre Hougvej 55, 5500 Middelfart, Denmark.

Background Context: Percutaneous vertebroplasty (PVP) and kyphoplasty (KP) are minimally invasive treatment options for vertebral compression fractures (VCFs) due to malignancy.

Purpose: To perform a systematic review evaluating the effectiveness and safety of vertebral augmentation for malignant VCFs.

Study Design: Systematic review. Read More

Medicine (Baltimore) 2019 Feb;98(8):e14317

Objective: To contrast the effects and complications in unilateral and bilateral percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures in elderly patients.

Methods: Multiple databases were adopted to search relevant studies, and the articles eventually satisfied the criteria were included. All the meta-analyses were conducted with the Review Manager 5. Read More

Blood Cancer J 2019 Feb 26;9(3):27. Epub 2019 Feb 26.

University of Athens School of Medicine, Athens, Greece.

Multiple myeloma (MM) represents approximately 15% of haematological malignancies and most of the patients present with bone involvement. Focal or diffuse spinal osteolysis may result in significant morbidity by causing painful progressive vertebral compression fractures (VCFs) and deformities. Advances in the systemic treatment of myeloma have achieved high response rates and prolonged the survival significantly. Read More

Clin Interv Aging 2019 5;14:265-270. Epub 2019 Feb 5.

Department of Spine Surgery, Hong Hui Hospital, Xi'an Jiaotong University, Xi'an 710054, Shaan'xi Province, China,

Objective: The objective of this study was to evaluate the effectiveness of bracing after percutaneous vertebroplasty (PVP) for thoracolumbar osteoporotic vertebral compression fractures (OVCF).

Methods: This is a retrospective study where we recruited 138 patients with single-level thoracolumbar OVCF who underwent PVP from January 2018 to March 2018 without bracing after PVP (Group A). The visual analog score (VAS) and vertebral body compression ratio (VCR) were recorded at preoperation, on the second day, at 2 weeks, 1 month, and 6 months after operation. Read More

Neuroradiology 2019 Apr 18;61(4):405-410. Epub 2019 Feb 18.

Department of Radiology, Centre Hospitalier Universitaire de Bordeaux, Bordeaux, France.

Purpose: To assess the feasibility and clinical outcome of combined CT and fluoroscopy-guided percutaneous vertebroplasty in the management of painful Schmorl's nodes (SN).

Methods: A prospective study was carried out from January 2014 to January 2016 in 52 consecutive patients. Thirty-two men and 30 women aged between 42 and 88 years old were consecutively included. Read More

J Orthop Surg Res 2019 Feb 11;14(1):42. Epub 2019 Feb 11.

Department of Orthopaedics, Beijing Chao-Yang Hospital, Capital Medical University, No.8 Gongren Tiyuguan Nanlu, Chaoyang district, Beijing, China.

Background: Multiple myeloma (MM) is a blood system malignant tumor, which often leads to osteolytic bone destruction, and the vertebral column is the primary site of involvement. However, the efficacy and prognosis of percutaneous kyphoplasty/vertebroplasty (PKP/PVP) for simple vertebral pathological fractures in patients with multiple myeloma are not yet unified. The primary objective of this study was to investigate the efficacy and prognosis of PKP/PVP in the treatment of multiple myeloma patients with vertebral pathological fractures. Read More

Pain Physician 2019 01;22(1):63-68

Department of Spine Surgery, Wuhan No. 1 Hospital, Wuhan, China.

Objective: To investigate the therapeutic effectiveness of percutaneous kyphoplasty (PKP) combined with zoledronic acid in treatment of primary osteoporotic vertebral compression fractures.

Study Design: A perspective cohort study was conducted at a single institution for patients, who received PKP operation due to primary osteoporotic vertebral compression fracture between January 2014 and January 2015.

Setting: According to whether they received postoperative zoledronic acid or not, patients were divided into treatment or control groups, with 30 randomly-selected cases per group. Read More

Ann Palliat Med 2019 Jan 2. Epub 2019 Jan 2.

Division of Radiation Oncology, Sunnybrook Hospital, Toronto, Ontario, Canada.

Multiple new options are available in the palliation of bone metastases. Most of these techniques can be used in conjunction with radiation therapy either before or after and are now giving patients who have reached dose limitations new options. These techniques can also be used with vertebroplasty (VP) to increase structural stability post tumor ablation. Read More

World Neurosurg 2019 Jan 22. Epub 2019 Jan 22.

School of Computing, Korea Advanced Institute of Science and Technology, Daejeon, Korea.

Objective: This study aimed to analyze the risk factors for secondary new vertebral compression fractures (SNVCFs) after percutaneous vertebroplasty (PVP) for osteoporotic vertebral compression fractures.

Methods: We evaluated the association of SNVCFs (adjacent vertebral compression fractures [AVCFs] and remote vertebral compression fractures) with clinical, radiographic, and PVP procedure-related morphologic parameters based on the data collected from 402 patients over a minimum follow-up of 4 years after PVP. Procedure-related morphologic parameters were assessed using a three-dimensional voxel-based analysis. Read More

J Bone Miner Res 2019 Jan;34(1):3-21

Center for Advanced Orthopedic Studies, Beth Israel Deaconess Medical Center, Boston, MA, USA.

Vertebral augmentation is among the current standards of care to reduce pain in patients with vertebral fractures (VF), yet a lack of consensus regarding efficacy and safety of percutaneous vertebroplasty and kyphoplasty raises questions on what basis clinicians should choose one therapy over another. Given the lack of consensus in the field, the American Society for Bone and Mineral Research (ASBMR) leadership charged this Task Force to address key questions on the efficacy and safety of vertebral augmentation and other nonpharmacological approaches for the treatment of pain after VF. This report details the findings and recommendations of this Task Force. Read More

Osteoporos Int 2019 Feb 12;30(2):287-298. Epub 2019 Jan 12.

Department of Spine Surgery, Tianjin Union Medical Center, 190 Jieyuan Road, Hongqiao District, Tianjin, China.

The aim of the current study was to use a Bayesian network meta-analysis to evaluate the relative benefits and risks of balloon kyphoplasty (BK), percutaneous vertebroplasty (PVP), and non-surgical treatment (NST) for patients with osteoporotic vertebral compression fractures (OVCFs). The results demonstrate that for pain and functional status, PVP was significantly better than NST, while the three treatments did not significantly differ in other outcomes.

Introduction: BK, PVP, and NST are widely used to treat OVCFs, but preferable treatment is unknown. Read More

J Coll Physicians Surg Pak 2019 Jan;29(1):37-40

Department of Orthopedics, JiZhong Energy XingTai Mining Group General Hospital, Xingtai, 054000, China.

Objective: To investigate the effects of percutaneous kyphoplasty on bone metabolism and oxidative stress in elderly patients with osteoporotic spinal fractures.

Study Design: An experimental study.

Place And Duration Of Study: Department of Orthopedics, ZhangYe People's Hospital Affiliated to HeXi University, from February 2016 to October 2017. Read More

Zhongguo Gu Shang 2018 Dec;31(12):1168-1171

Department of Orthopaedics, the Second Hospital Affiliated to Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, Guangdong, China;

Objective: To evaluate the clinical value of contralateral supplementary puncture in unilateral percutaneous vertebroplasty(PVP) with poor cement dispersion.

Methods: From January 2015 to December 2016, PVP was performed unilaterally in 285 patients(319 vertebrae) with osteoporotic compression fractures(OVCF). Contralateral percutaneous puncture was performed in 13 patients with poor cement dispersion. Read More

Spine (Phila Pa 1976) 2019 Jan;44(2):123-133

Department of Radiology, Section of Interventional Radiology, Rush University Medical Center, Chicago, IL.

Study Design: Retrospective analysis of Medicare data OBJECTIVE.: To analyze trends of vertebral augmentation in the elderly Medicare population in the context of evolving evidence and varied medical society opinions.

Summary Of Background Data: Percutaneous vertebral augmentation offers a minimally invasive therapy for vertebral compression fractures. Read More

Malays Orthop J 2018 Nov;12(3):6-13

*Emergency Room Department, Jombang General Hospital, Jombang, Indonesia.

Percutaneous vertebroplasty (PV) is one of the available treatments for vertebral compression fracture (VCF). Polymethylmethacrylate (PMMA) is the most common bone substitute used in the procedure, but it has several disadvantages. Bioceramic material, such as hydroxyapatite (HA), has better biological activity compared to PMMA. Read More

J Neurointerv Surg 2018 Dec 14. Epub 2018 Dec 14.

Department of Neuroradiology, Papa Giovanni XXIII Hospital, Bergamo, Italy.

Objectives: To describe a new technique to obtain minimally invasive but efficient vertebral body (VB) reconstruction, augmentation, and stabilization in severe osteoporotic and neoplastic fractures, combining two pre-existing procedures. The implant of vertebral body stents (VBS) is followed by insertion of percutaneous, fenestrated, cement-augmented pedicular screws that act as anchors to the posterior elements for the cement/stent complex. The screws reduce the risk of stent mobilization in a non-intact VB cortical shell and bridge middle column and pedicular fractures. Read More

PLoS One 2018 10;13(12):e0208578. Epub 2018 Dec 10.

Division of General Internal Medicine, Bern University Hospital, Inselspital, University of Bern, Bern, Switzerland.

Background: Percutaneous vertebroplasty (VP) and balloon kyphoplasty (BKP) for treating painful osteoporotic vertebral fractures are controversial.

Objective: We assessed the regional variation in the use of VP/BKP in Switzerland.

Methods: We conducted a population-based small area variation analysis using patient discharge data for VP/BKP from all Swiss hospitals and Swiss census data for calendar years 2012/13. Read More

Jpn J Radiol 2019 Feb 1;37(2):178-185. Epub 2018 Dec 1.

Department of Radiology, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

Objective: To retrospectively analyze the safety and efficacy of percutaneous vertebroplasty (PVP) for patients aged 90 or over.

Materials And Methods: We analyzed 130 consecutive patients with osteoporotic vertebral fractures who underwent a first-time PVP between May 2015 and September 2017 at our institution. We divided them into the elder patient group aged 90 years or over (n = 21) and the younger patient group under 90 years (n = 109). Read More

World Neurosurg 2019 Mar 29;123:e408-e415. Epub 2018 Nov 29.

The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, Guangxi. Electronic address:

Objective: To determine cement distribution patterns on therapeutic efficacy after percutaneous vertebroplasty treatment of osteoporotic vertebral compression fractures (OVCFs) with intravertebral cleft (IVC).

Methods: Patients who were treated with percutaneous vertebroplasty for single OVCFs with IVC and met this study's inclusion criteria were retrospectively reviewed. The follow-up period was at least 2 years. Read More

Zhongguo Gu Shang 2018 Nov;31(11):993-997

Department of Spinal Surgery, Integrated Traditional Chinese and Western Medicine Hospital of Wenzhou Affiliated to Zhejiang Chinese Medicine University, Wenzhou 325000, Zhejiang, China.

Objective: To explore the clinical effects of bone filling bag vertebroplasty in treating osteoporotic vertebral compression fractures.

Methods: The clinical data of 127 patients (145 vertebrae) with osteoporotic vertebral compression fractures who corresponded the criteria of inclusion and exclusion from December 2015 to June 2017 were retrospectively analyzed. Responsible vertebral bodies were identified by clinical situation, X-rays, CT scan, MRI. Read More

Eur Radiol 2018 Dec 3. Epub 2018 Dec 3.

2nd Department of Radiology, Attikon General University Hospital, National and Kapodistrian University of Athens, Rimini 1, Haidari, 12462, Athens, Greece.

Objectives: The purposes of the study were to evaluate the safety and long-term efficacy of augmented vertebroplasty using a polyether ether ketone (PEEK) implant, for the treatment of lumbar or thoracic vertebral fractures (A2 according to the Magerl's AO classification) and to analyze pain reduction, height restoration, and complications during a 2-year follow-up period.

Methods: Prospective non-randomized evaluation was performed for 21 painful split vertebral fractures (20 patients, 14 females, 6 males; mean age 72.80 ± 10. Read More

Asian Spine J 2019 Apr 29;13(2):305-312. Epub 2018 Nov 29.

Unité Rachis, Hopital de La Timone, Assistance Publique des Hopitaux de Marseille, Marseille, France.

Study Design: Retrospective case series observational study.

Purpose: Cancer patients are often aged and are further weakened by their illness and treatments. Our goal was to evaluate the efficiency and safety of using minimally invasive techniques to operate on spinal fractures in these patients. Read More

World Neurosurg 2019 Feb 24;122:e1599-e1605. Epub 2018 Nov 24.

Department of Neurological Surgery, University of California Davis, Sacramento, California, USA.

Objective: Percutaneous vertebroplasty (VP) and medial branch block (MBB) are used to treat osteoporotic vertebral compression fractures (VCF). We compared the clinical outcomes, radiologic changes, and economic results of MBB with those of VP in treating osteoporotic VCFs.

Methods: A total of 164 patients with 1-level osteoporotic VCF were reviewed retrospectively. Read More

World Neurosurg 2019 Feb 19;122:e1381-e1387. Epub 2018 Nov 19.

Department of Orthopaedics, Chengdu First People's Hospital, Chengdu, China.

Objective: Data reporting percutaneous vertebroplasty (PVP) or percutaneous balloon kyphoplasty (PKP) application to the midthoracic vertebrae remain limited. This study aimed to summarize our experiences and explore the efficacy and safety of PVP or PKP in dealing with osteoporotic vertebral compression fracture (OVCF) in the midthoracic vertebrae.

Methods: Patients receiving PVP or PKP for midthoracic OVCF in our institution from January 2015 to January 2018 were retrospectively enrolled. Read More

J Pain Res 2018 26;11:2625-2631. Epub 2018 Oct 26.

Department of Spine Surgery, The Third Hospital of Hebei Medical University, 050051 Shijiazhuang, China,

Purpose: The purpose of this study was to compare the clinical efficacy and safety of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of the elderly with very severe osteoporotic vertebral compression fractures (vsOVCFs).

Methods: From September 2012 to September 2015, 57 patients with vsOVCFs who had undergone PVP and PKP surgeries at our medical center were reviewed retrospectively, at least 2 years follow-up. All patients were divided into PVP group (n=31) and PKP group (n=26). Read More

Acta Orthop Belg 2018 Mar;84(1):105-107

We assessed the results of percutaneous vertebroplasty treatment of painful vertebral hemangiomas in 110 patients, with a three years follow-up. 110 patients with painful vertebral hemangiomas were treated by percutaneous vertebroplasty. The patients were diagnosed by MRI and observed for 3 years after surgery. Read More

World Neurosurg 2019 Feb 9;122:266-271. Epub 2018 Nov 9.

Department of Spinal Surgery, General Hospital, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, China. Electronic address:

Background: We reviewed the reported data related to iatrogenic lumbar artery injury (ILAI) in spine surgery with a focus on which iatrogenic procedure might cause lumbar artery injury.

Methods: We conducted a comprehensive search in the Web of Science, PubMed, EMBASE, and Chinese biomedical databases in July 2018.

Results: A total of 20 reports on ILAI were selected for the present study. Read More

J Clin Neurosci 2019 Jan 7;59:146-154. Epub 2018 Nov 7.

Department of Orthopaedics, Beijing Chao-Yang Hospital, China Capital Medical University, No. 8 GongTiNanLu, Chao-Yang District, Beijing 100020, China. Electronic address:

The objective of the research was to compare the efficacy of lateral and bilateral PKP approaches for OVCFs. A comprehensive literature search was performed from the PubMed, Cochrane Library and Embase between January 2008 and May 2017. The clinical efficacy of the two approaches was evaluated by comparing perioperative outcomes (operation time, the volume of injected cement, X-ray exposure times and mean radiation dose), clinical outcomes (kyphotic angle reduction, restoration rate, visual analogue scale [VAS], Oswestry Disability Index [ODI] and SF-36), and operation-related complications (cement leakage and adjacent vertebral fracture). Read More

World Neurosurg 2019 Feb 7;122:e1020-e1027. Epub 2018 Nov 7.

Department of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.

Background: Although percutaneous kyphoplasty (PKP) is performed to restore the vertebral body height and kyphosis in osteoporotic vertebral compression fractures (OVCFs), the regained height may be lost on balloon deflation. This study compares PKP with modified percutaneous kyphoplasty (MPKP) in terms of the clinical outcomes in treating OVCFs.

Methods: Between May 2014 and March 2016, 76 patients with OVCFs were randomly assigned to 2 groups according to the procedure chosen: the PKP group (n = 36) and MPKP group (n = 40). Read More

Semin Intervent Radiol 2018 Oct 5;35(4):309-323. Epub 2018 Nov 5.

Service de Radiologie Ostéoarticulaire, Viscérale et Vasculaire, Hôpital Lariboisière, APHP, Université Paris-Diderot, Paris, France.

Percutaneous vertebral augmentation/consolidation techniques are varied. These are vertebroplasty, kyphoplasty, and several methods with percutaneous introduction of an implant (associated or not with cement injection). They are proposed in painful osteoporotic vertebral fractures and traumatic fractures. Read More

Semin Intervent Radiol 2018 Oct 5;35(4):221-228. Epub 2018 Nov 5.

Department of Radiology, Institut Bergonie, Bordeaux, France.

Occurrence of bone metastases is a common event in oncology. Bone metastases are associated with pain, functional impairment, and fractures, particularly when weight-bearing bones are involved. Management of bone metastases has been improved by the development of various interventional radiology consolidation techniques. Read More

Cochrane Database Syst Rev 2018 11 6;11:CD006349. Epub 2018 Nov 6.

Monash Department of Clinical Epidemiology, Cabrini Institute, Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, 4 Drysdale Street, Malvern, Victoria, Australia, 3144.

Background: Percutaneous vertebroplasty remains widely used to treat osteoporotic vertebral fractures although our 2015 Cochrane review did not support its role in routine practice.

Objectives: To update the available evidence of the benefits and harms of vertebroplasty for treatment of osteoporotic vertebral fractures.

Search Methods: We updated the search of CENTRAL, MEDLINE and Embase and trial registries to 15 November 2017. Read More

Clin Spine Surg 2019 Mar;32(2):E99-E106

The Second Department of Orthopedics, The Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou City, PR China.

Study Design: This was a clinical retrospective study.

Objectives: This retrospective study aimed to investigate the incidence of new vertebral compression fractures (NVCFs) and analyze the risk factors that influence the secondary fractures in adjacent and nonadjacent levels after percutaneous vertebroplasty (PVP) and conservative treatment (CT).

Summary Of Background Data: PVP is an effective procedure to alleviate the pain caused by osteoporotic vertebral compression fractures. Read More

World Neurosurg 2019 Feb 1;122:342-348. Epub 2018 Nov 1.

Department of Spinal Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, People's Republic of China.

Background: A meta-analysis of randomized controlled trials (RCTs) was performed to compare the incidence of cement leakage between unilateral and bilateral percutaneous vertebral augmentation (PVA) in treating osteoporotic vertebral compression fractures (OVCFs).

Methods: PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials were searched to retrieve the reported data from the establishment of the databases until August 1, 2018. The RCTs on unilateral and bilateral PVA for OVCFs were included. Read More

Osteoporos Int 2019 Feb 28;30(2):423-430. Epub 2018 Oct 28.

Department of Spinal Surgery, Tongde Hospital of Zhejiang Province, Gucui Road 234, Hangzhou, Zhejiang, People's Republic of China.

Our study demonstrated a high incidence of recollapse of the augmented vertebrae after PVP treatment for OVCFs. A risk score based on all significant factors can predict the rate of recollapse and gain clinical benefits to prevent recollapse in patients at high risk.

Background: Recollapse of the augmented vertebrae after percutaneous vertebroplasty (PVP) treatment for osteoporotic vertebral compression fractures (OVCFs) has obtained much attention. Read More

Interv Med Appl Sci 2018 Mar;10(1):1-6

Department of Neurosurgery, Bou Ali Hospital, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.

Background: Vertebral fractures (VFs) are the most usual convolution of metastatic tumors and the vertebral column is the third most ordinary site for painful bone metastases and remains a chief factor of morbidity in cancer patients.

Methods: In this paper, we investigated the previous literature on the status of clinical and prospects for the use of percutaneous vertebroplasty (PVP) with polymethylmethacrylate as a remedial alternative for the therapy of refractory pain resulting from malignant vertebral compression and pathologic fractures associated with metastatic tumors of various sites in numerous studies. The scientific document for this remedy, containing safety, immediate and long-term efficacy, and outcome measures, and also the risks of complications, was analyzed in detail. Read More

BJR Case Rep 2018 12;4(2):20170092. Epub 2018 Feb 12.

Department of Radiology, Cappagh National Orthopaedic Hospital of Ireland, Finglas, Dublin, Ireland.

Vertebroplasty is a recognised treatment for osteoporotic and pathological compression fractures. We present the case of TF, a 70-year-old male patient with a history of poor left ventricular function presenting with refractory lower back pain, thought to be secondary to Modic Type1 changes in the L2 and L3 vertebrae, accompanying L2-L3 degenerative disc disease. He was treated conservatively for approximately 9 months without success. Read More

J Orthop Surg Res 2018 Oct 25;13(1):268. Epub 2018 Oct 25.

Department of Orthopaedic Surgery, Nanjing First Hospital, Nanjing Medical University, #68 Changle Rd, Qinhuai District, Nanjing, 210000, Jiangsu, China.

Background: Percutaneous kyphoplasty (PKP) is widely applied for the treatment of osteoporotic vertebral compression fractures (OVCFs) and has achieved satisfactory clinical results. With the accumulation of clinical cases and prolonged follow-up times, the inability to reconstruct vertebral height defects has attracted more and more attention. A comparison of clinical effects was retrospectively reviewed in 72 patients who underwent simple PKP or pedicle in vitro restorer (PIVR) combined with PKP to discuss the clinical application of self-developed PIVR used in PKP. Read More