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Theranostics 2020 17;10(14):6544-6560. Epub 2020 May 17.

Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine & Key Laboratory of Musculoskeletal System Degeneration and Regeneration Translational Research of Zhejiang, Hangzhou 310016, China.

Poly (methyl methacrylate) (PMMA) bone cement is one of the most commonly used biomaterials for augmenting/stabilizing osteoporosis-induced vertebral compression fractures (OVCFs), such as percutaneous vertebroplasty (PVP) and balloon kyphoplasty (BKP). However, its clinical applications are limited by its poor performance in high compressive modulus and weak bonding to bone. To address these issues, a bioactive composite bone cement was developed for the treatment of osteoporotic vertebral compression fractures, in which mineralized collagen (MC) was incorporated into the PMMA bone cement (MC-PMMA). Read More

J Int Med Res 2020 May;48(5):300060520926005

Division of Pulmonology, Department of Internal Medicine, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.

Pulmonary cement embolism (PCE) is one of several complications of percutaneous vertebroplasty and kyphoplasty. Generally, PCE can be easily diagnosed based on typical chest radiograph findings such as single or multiple radiographically dense opacities with a tubular or branch shape in the lung field along with a recent history of percutaneous vertebroplasty or kyphoplasty. These findings can be alarming and may be encountered on routine chest radiographs, even in asymptomatic patients. Read More

J Int Med Res 2020 May;48(5):300060520925390

Department of Orthopedics, Peking University First Hospital, Beijing, China.

Objectives: This study analyzed the effects of rosuvastatin and zoledronic acid in combination on patient recovery following percutaneous vertebroplasty (PVP) that was performed to treat senile osteoporotic vertebral compression.

Methods: Senile patients with osteoporotic vertebral compression fracture (n = 120) were included in this retrospective study, and they were classified into two groups. Those in the control group (n = 60) were treated with PVP + caltrate and those in the observation group (n = 60) received this treatment with combined zoledronic acid and rosuvastatin. Read More

J Korean Neurosurg Soc 2020 May 27. Epub 2020 May 27.

Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.

Objective: To evaluate the effectiveness and long-term outcome predictors of percutaneous sacroplasty (PSP).

Methods: This single-center study assessed 40 patients with sacral insufficiency fractures using the short-axis technique under C-arm flat-panel detector computed tomography (CT). Two radiologists reviewed the patients' magnetic resonance and CT images to obtain imaging findings before PSP and determine technical success, respectively. Read More

Zhongguo Gu Shang 2020 May;33(5):445-8

Department of Traumatology and Orthopaedics, Yanjishan Hospital, Wannan Medical College, Wuhu 241000, Anhui, China.

Objective: To investigate the influencing factors of hidden blood loss (HBL) during the treatment of percutaneous vertebroplasty (PVP).

Methods: The clinical data of 125 patients with osteoporotic vertebral compression fractures (OVCFs) treated with percutaneous vertebroplasty from March 2016 to December 2017 were retrospectively analyzed. All patients underwent X rays of the AP and lateral lumbar spine, double oblique, and dynamic positions. Read More

Ann Palliat Med 2020 May 18. Epub 2020 May 18.

Shanghai General Hospital of Nanjing Medical University, Shanghai 201600, China.

Background: Establishment of a three-dimensional (3D) finite element model of osteoporosis, the simulation fluid was used to enter the vertebral body to study the stiffness recovery of injured vertebral body under different perfusion and distribution conditions, and the stress analysis of adjacent vertebral body after percutaneous vertebroplasty (PVP) was carried out.

Methods: A healthy male volunteer was selected. Computed tomography (CT) scanning was performed from T11 to L2. Read More

BMC Surg 2020 May 7;20(1):96. Epub 2020 May 7.

Department of Spine, Sichuan Orthopedic Hospital, No.132, the west 1st section of Yihuan Road, Chengdu, 610041, China.

Background: Osteoporotic thoracolumbar burst fracture (OTLBF) is common in seniors. Due to the fracture of the posterior vertebra and spinal canal occupancy, the risk of cement leakage and spine injury is high in OTLBF patients, thus the application of vertebroplasty and kyphoplasty is limited in these patients. This study aims to investigate the efficacy and safety of the modified percutaneous kyphoplasty (MPKP) in the treatment of OTLBF. Read More

Eur Spine J 2020 May 2. Epub 2020 May 2.

Department of Oncological and Degenerative Spine Surgery, IRCCS Istituto Ortopedico Rizzoli, Via G.C. Pupilli, 1, 40136, Bologna, Italy.

Purpose: The purpose of this study is to compare the efficacy and safety of percutaneous vertebroplasty (PVP) and balloon kyphoplasty (BKP) in the treatment of osteoporotic vertebral compression fractures.

Materials And Methods: Patients with osteoporotic vertebral body fractures (T4-L5) were randomized and not blinded to kyphoplasty (n = 69) or vertebroplasty (n = 70). The postoperative pain score (VAS) at 12 months was the primary end point. Read More

Eur Radiol 2020 May 2. Epub 2020 May 2.

Department of Medical Imaging, Medical Imaging Group Nimes, CHU Nimes, Univ Montpellier, EA 2415, Bd Prof Robert Debré, 30029, Nîmes Cedex 9, France.

Objectives: To establish national reference levels (RLs) in interventional procedures under CT guidance as required by the 2013/59/Euratom European Directive.

Methods: Seventeen categories of interventional procedures in thoracic, abdominopelvic, and osteoarticular specialties (percutaneous infiltration, vertebroplasty, biopsy, drainage, tumor destruction) were analyzed. Total dose length product (DLP), number of helical acquisitions (NH), and total DLP for helical, sequential, or fluoroscopic acquisitions were recorded for 10 to 20 patients per procedure at each center. Read More

Medicine (Baltimore) 2020 May;99(18):e20072

Department of Internal Medicine, Kuang Tien General Hospital.

Vertebral compression fractures (VCFs) are common in elderly and are treated with immobilization. Moreover, immobilization and old age may increase venous thromboembolism (VTE) risk. However, the incidence of VCFs-related VTE is unknown in elderly. Read More

Eur Spine J 2020 Apr 27. Epub 2020 Apr 27.

Design and Materials for Medical Equipment and Devices, Da-Yeh University, Changhua, Taiwan, ROC.

Purpose: This study aimed to demonstrate that the augmented reality computer-assisted spine surgery (ARCASS) system is clinically feasible for percutaneous vertebroplasty (PVP).

Methods: This prospective case-control study included the patients undergoing PVP under the assistance of the ARCASS system between July 1, 2013, and October 31, 2014. The control group was the age- and gender-matched patients who underwent standard PVP and met the same eligible criteria as the case group. Read More

Medicine (Baltimore) 2020 Apr;99(17):e19816

Department of Orthopedics, General Hospital of Northern Theater Command of Chinese PLA.

Anatomical differences of unilateral percutaneous kyphoplasty (PKP) between transverse process-pedicle approach (TPPA) and conventional transpedicular approach (CTPA) are not well discussed. To investigate the anatomical distinctions of unilateral PKP between TPPA and CTPA, we have discussed the unilateral PKP through a 3-dimensional-computed tomography database.Five hundred lumbar spines from 100 patients have been retrospectively collected and unilateral CTPA and TPPA were simulated. Read More

Skeletal Radiol 2020 Apr 24. Epub 2020 Apr 24.

Department of Medical Imaging, 960 Hospital of PLA, Jinan, 250031, Shandong Province, China.

Objective: To evaluate the efficacy of a new technique of percutaneous vertebral augmentation (PVA): drill rotation-cement injected under vacuum aspiration (DR-CIVAS) for vertebral compression fractures (OVCFs) with intravertebral vacuum cleft (IVC) sign.

Materials And Methods: A retrospective study was conducted in 46 consecutive patients with OVCFs and IVC signs, who underwent PVA using DR-CIVAS (n = 22, DR-CIVAS group) or traditional technique without DR-CIVAS (n = 24, control group). The pre- and postoperative vertebral height and wedge angle change and visual analog scale (VAS), the volume of cement injected, incidences of cement leakage, and subsequent new vertebral compression fractures were evaluated between the two groups. Read More

BMC Musculoskelet Disord 2020 Apr 17;21(1):255. Epub 2020 Apr 17.

Department of Health Economics, Shanghai Centennial Co. Ltd, AD: 702A, B Block, Fenglin International Center, No. 388 Fenglin Road, Shanghai, 200030, PR China.

Background: Osteoporotic vertebral compression fractures (OVCF) is a common and often debilitating complication of osteoporosis, leading to significant morbidity and increased mortality. Percutaneous vertebroplasty (PVP) and Percutaneous kyphoplasty (PKP) are recommendable surgical treatments for OVCF.

Objective: To evaluate PVP/PKP utilisation and their related direct medical costs for OVCF treatment in China from the payer perspective. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2020 Apr;34(4):428-434

Department of Spine Surgery, the Fourth People's Hospital of Guiyang City, Guiyang Guizhou, 550002, P.R.China.

Objective: To discuss the safety and effectiveness of the improved technique by comparing the effects of low temperature bone cement infusion before and after the improvement in the percutaneous vertebroplasty (PVP).

Methods: The clinical data of 170 patients (184 vertebrae) with osteoporotic vertebral compression fracture who met the selection criteria between January 2016 and January 2018 were retrospectively analyzed. All patients were treated with PVP by low-temperature bone cement perfusion technology. Read More

BMC Musculoskelet Disord 2020 Apr 13;21(1):238. Epub 2020 Apr 13.

Department of Orthopedic Surgery, CR & WISCO General Hospital, Wuhan University of Science and Technology, No. 209 Yejin Road, Wuhan, 430000, Hubei Province, People's Republic of China.

Background: Percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) are widely used in the treatment of Kümmell's disease. The purpose of this article is to investigate the clinical efficacy of PVP and PKP for Kümmell's disease.

Methods: The clinical data that 56 cases of Kümmell's disease treated with either PVP (28 cases) or PKP (28 cases) from December 2015 to December 2017 were prospectively analyzed. Read More

Eur Spine J 2020 Apr 10. Epub 2020 Apr 10.

Spine Unit, Département Des Neurosciences Cliniques, Service de Neurochirurgie, Geneva University Hospitals, Rue Gabrielle-Perret-Gentil 4, 1205, Geneva, Switzerland.

Purpose: Vertebral hemangiomas (VH) account for 2-3% of all spinal tumors. The majority is incidentally found on radiographic studies: 1% present with pain and/or neurologic deficits. We report our experience with the multidisciplinary management of aggressive symptomatic thoracic VH by concomitant intraoperative sclerotization with sodium tetradecyl sulfate (STS), vertebroplasty, posterior decompression (with/without fusion) and surgical resection in a hybrid operating room (HR) equipped with a rotational scanner and a radiolucent operating table. Read More

Eur Spine J 2020 Apr 3. Epub 2020 Apr 3.

Center for Spine Surgery and Research, Lillebaelt Hospital, Oestre Hougvej 55, 5500, Middelfart, Denmark.

Purpose: To summarize the recommendations from the national clinical guideline published by the Danish Health Authority, regarding cemental augmentation as treatment for painful vertebral lesions, in patients with malignant disease.

Methods: A multidisciplinary working group formulated recommendations based on the GRADE approach.

Results: Two of the questions were based on randomized studies and one on professional consensus. Read More

Osteoporos Sarcopenia 2020 Mar 3;6(1):1-7. Epub 2020 Mar 3.

Department of Medicine, Tuen Mun Hospital, Hong Kong, China.

The vertebral column is the most common site of osteoporotic fractures in long-term users of glucocorticoids. Vertebral fracture leads to significant morbidities such as unrelenting pain, spinal deformities and reduced mobility, leading to diminished quality of life. Epidemiological data on the prevalence of glucocorticoid-induced vertebral fractures are limited. Read More

J Spine Surg 2020 Jan;6(Suppl 1):S208-S223

Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada.

Background: Minimally invasive spine surgery (MISS) and endoscopic spine surgery have continually evolving indications in the cervical, thoracic, and lumbar spine. Endoscopic spine surgery entails treatment of disc disease, stenosis, spondylolisthesis, radiculopathy, and deformity. MISS involves complex motor skills in regions of variable anatomy. Read More

Medicine (Baltimore) 2020 Mar;99(11):e19354

Department of Cardiovascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Rationale: Leakage of bone cement is a common complication after percutaneous kyphoplasty. In rare cases, bone cement can leak into the venous system, which can be life threatening, especially when it causes an embolism in the heart.

Patient Concerns: A 79-year-old female patient developed chest pain with chest tightness 3 weeks after the percutaneous kyphoplasty. Read More

Rev Med Suisse 2020 Mar;16(685):492-497

Service de rhumatologie et Centre des maladies osseuses, CHUV, 1011 Lausanne.

Should we continue to treat patients suffering from an acute osteoporotic vertebral fracture with vertebroplasty ? What is the potential benefit ? What are its indications ? What are its risks ? Which way to perform it ? How to manage the osteoporosis evaluation and therapy ? In 2009 we published the « CHUV consensus » on the management of vertebral osteoporotic fractures by vertebroplasty. We here propose an update including recent knowledge on the management of vertebral fractures by bone insufficiency by percutaneous cementoplasty. Read More

Chirurg 2020 Mar 10. Epub 2020 Mar 10.

Praxisklinik Dr. Homagk - MVZ GmbH, Schillerstraße 14, 06667, Weißenfels, Deutschland.

Approximately 200,000 spinal fractures occur each year in Germany. The decimated stability of the vertebra often leads to type A fractures with a substantial influence by osteoporosis. A mobility preserving and gentle treatment has clear advantages compared to conservative treatment. Read More

Regen Biomater 2020 Feb 16;7(1):29-34. Epub 2020 Jan 16.

State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China.

To examine the clinical effects of a new bone cement composed of poly(methyl methacrylate) (PMMA) and mineralized collagen (MC) compared with pure PMMA bone cement in treating osteoporotic vertebral compression fractures (OVCFs) in patients aged over 80. In all, 32 cases using pure PMMA bone cement and 31 cases using MC-modified PMMA (MC-PMMA) bone cement for OVCFs between June 2014 and March 2016 were screened as PMMA group and MC-PMMA group, respectively, with an average age of over 80. The operation duration, intraoperative blood loss, hospital stay, oswestry disability index (ODI), visual analogue scale (VAS), anterior vertebral height (AVH), intermediate vertebral height (IVH) and posterior vertebral height (PVH) of injured vertebrae, vertebral computed tomography value, re-fracture rate of adjacent vertebrae, correction rate of spinal kyphotic angle and wedge-shaped vertebra angle and surgical complications were compared between the two groups. Read More

Pain Med 2020 Mar 9. Epub 2020 Mar 9.

National Cancer Institute Mexico City, Mexico City, México.

Objective: Vertebroplasty is a percutaneous minimally invasive procedure indicated for vertebral collapse pain treatment. Among the known complications of the procedure is the augmented risk of new vertebral fractures. There are no specific studies in this patient population describing the risk of new vertebral fractures after vertebroplasty. Read More

Spine (Phila Pa 1976) 2020 Mar 6. Epub 2020 Mar 6.

Department of Neurosurgery, Koç University Hospital, Istanbul, Turkey.

Study Design: Technique note OBJECTIVE.: To evaluate the feasibility of endoscopy in various spinal pathologies SUMMARY OF BACKGROUND DATA.: Osteoporotic vertebral fractures are a common pathology in the elderly. Read More

Medicine (Baltimore) 2020 Mar;99(10):e19402

Department of Orthopaedic Surgery, Shengzhou People's Hospital, The First Affiliated Hospital of Zhejiang University Shengzhou Branch, Zhejiang, China.

In recent years, deep venous thrombosis (DVT) after spine surgery has received extensive attention, but perioperative prevalence of DVT in patients undergoing percutaneous kyphoplasty (PKP) is lacking.To assess the perioperative prevalence of deep vein thrombosis (DVT) in patients undergoing PKP with routinely applied ultrasonography.We reviewed 1113 consecutive patients undergoing PKP from January 2014 to August 2017. Read More

World Neurosurg 2020 Mar 3. Epub 2020 Mar 3.

Department of Neurosurgery, Istanbul University Faculty of Medicine, Istanbul, Turkey.

Objective: The aim to evaluate central sarcopenia, as measured by psoas cross-sectional area on admission imaging, is associated with outcomes in patients with vertebral compression fractures (VCFs) treated with percutaneous vertebral augmentation treatment.

Methods: We evaluated the records of patients aged >60 years treated with vertebroplasty or kyphoplasty between 2009 and 2018 for osteoporotic VCFs. The Social Security Death Index was used to determine death. Read More

Zhongguo Gu Shang 2020 Feb;33(2):111-5

Department of Orthopaedics, the First People's Hospital of Huzhou, Huzhou 313000, Zhejiang, China.

Objective: To investigate the guiding significance of lumbar quantitative computed tomography (QCT) in percutaneous vertebroplasty (PKP) for osteoporotic vertebral compression fractures (OVCF).

Methods: The clinical data of 90 patients with OVCF underwent PKP from December 2017 to December 2018 were retrospectively analyzed. There were 24 femalesand66males, withanaverage agedof (74. Read More

J Vasc Interv Radiol 2020 Apr 29;31(4):686-689. Epub 2020 Feb 29.

Osteo-Articular Imaging Department, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, 2 rue Ambroise Paré, 75010 Paris, France.

Expert Rev Med Devices 2020 Apr 3;17(4):357-364. Epub 2020 Mar 3.

Department of Orthopedics, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian, China.

: To compare the effects of percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) in treating Kümmell's disease (KD) patients.: This prospective cohort study involved 19 KD patients (20 involved vertebrae). The surgical selection was dependent on clinical stages and postural correction status. Read More

Medicina (Kaunas) 2020 Feb 17;56(2). Epub 2020 Feb 17.

Department of Neurosurgery, China Medical University Hospital, Taichung 404, Taiwan.

Background: Osteoporotic spinal fractures commonly occur in elderly patients with low bone mineral density. In these cases, percutaneous vertebroplasty or percutaneous kyphoplasty can provide significant pain relief and improve mobility. However, studies have reported both the recurrence of vertebral compression fractures at the index level after vertebroplasty and the development of new vertebral fractures at the adjacent level that occur without any additional trauma. Read More

J Orthop Surg Res 2020 Feb 17;15(1):53. Epub 2020 Feb 17.

Tongren Hospital, School of Medicine, Shanghai Jiao Tong University, 1111 XianXia Road, Shanghai, 200336, People's Republic of China.

Background: To investigate the clinical effect of percutaneous pedicle screw fixation (PPSF) combined with percutaneous vertebroplasty (PVP) in the treatment of osteoporotic compression vertebral fracture (OVCF) of the thoracolumbar vertebra with kyphosis.

Methods: One hundred sixty-six patients before June 2017 were retrospectively analyzed, and patients were divided into PPSF + PVP group A and PVP group B. Operative time, bone mineral density, postoperative bed time, high compression ratio, bone cement leakage rate, and bone cement dose were recorded. Read More

J Thromb Thrombolysis 2020 Apr;49(3):468-474

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, 101 Daehak-Ro Jongno-Gu, Seoul, 03080, Republic of Korea.

The prognosis of pulmonary cement embolism found incidentally on chest radiography after vertebroplasty has been rarely investigated. This study was performed to elucidate the impact of incidentally found pulmonary cement embolism on all-cause mortality. Patients with pulmonary cement embolism diagnosed using chest radiography between 2008 and 2014 at one tertiary referral hospital were included. Read More

BMC Musculoskelet Disord 2020 Feb 7;21(1):82. Epub 2020 Feb 7.

Department of Orthopedics and Traumatology, Nantong Hospital of Chinese Medicine, Room 502 of Building 1 of Sujian Garden City, Chongchuan District, Nantong, China.

Background: Kümmell's disease is a special type of osteoporotic vertebral fracture that causes chronic low back pain and deformity, which seriously affects the living quality of patients. PVP is commonly used to treat osteoporotic vertebral fractures and can quickly relieve low back pain. So, the objective of this study was to analyze the clinical efficacy and experience of bipedicular percutaneous vertebroplasty combined with postural reduction for the treatment of Kümmell's disease. Read More

Cancer Lett 2020 Apr 4;475:136-142. Epub 2020 Feb 4.

Department of Bone Tumor, Tianjin Hospital, 406 Jiefang Southern Road, Tianjin, China. Electronic address:

Bone metastasis is a common complication of cancer, and bone is the third most common metastatic site following the lung and liver. Among the various bones, spine is the most common site of metastatic tumors. The treatment goals of patients with spinal metastases are mostly palliative, with the aim of reducing pain and improving quality of life. Read More

Ther Clin Risk Manag 2020 13;16:7-15. Epub 2020 Jan 13.

Department of Graduate School, Graduate School of Hebei Medical University, Shijiazhuang, Hebei 050000, People's Republic of China.

Purpose: To determine the risk factors for pulmonary complications after minimally invasive surgery in elderly patients with vertebral compression fractures (VCFs).

Methods: A total of 233 elderly patients (age ≥ 65 years) with VCFs, who underwent percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) surgery at Hebei General Hospital from January 2011 to December 2016, were retrospectively analyzed. Risk factors and the effects of the model were determined by univariate logistic regression analyses and the receiver operating characteristic (ROC) curve, respectively. Read More

Pain Physician 2020 01;23(1):E68

Shahid Behesti University of Medical Sciences School of Medicine Iran.

Pain Physician 2020 01;23(1):E31-E40

Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.

Background: Although percutaneous vertebroplasty (PVP) can effectively relieve the pain for patients with acute osteoporotic vertebral compression fractures (OVCFs), many patients still complain of mild back pain in the early postoperative period.

Objectives: The aim of this study was to assess the effect of early limited activity (LA) on prognosis after bipedicular small-cement-volume (i.e. Read More

J Invasive Cardiol 2020 Feb;32(2):E43

Istanbul Yeni Yuzyil University, Faculty of Medicine, Gaziosmanpasa Hospital, Cardiology Department, Gaziosmanpasa, Istanbul, Turkey.

Following percutaneous vertebroplasty for vertebral compression fracture 6 years prior, late pulmonary cement embolism developed after leakage of the cement into the paravertebral venous plexus. Read More

PLoS One 2020 30;15(1):e0228341. Epub 2020 Jan 30.

Department of Spine Surgery, Shandong Provincial Hospital affiliated to Shandong University, Jinan, P.R. China.

Background: Osteoporotic vertebral compression fractures (OVCFs) often cause local kyphosis. Percutaneous kyphoplasty (PKP) is a common method for the treatment of local kyphosis. However, the influence of kyphoplasty on spino-pelvic alignment and global sagittal balance when performed at specific treatment sites in the spine remains unclear. Read More

Radiologe 2020 Feb;60(2):138-143

Klinik für Neurochirurgie, Universitätsmedizin Rostock, Ernst-Heydemann-Str. 6, Rostock, 18057, Deutschland.

Background: Despite optimal drug-conservative therapy, a relevant percentage of patients with vertebral compression fractures (WKF) do not experience any relevant improvement in their pain symptoms. Vertebroplasty (VP) and kyphoplasty (KP) are described in the literature as percutaneous interventional procedures for the treatment of WKF.

Objective: Assessment of the effectiveness of the VP and KP in the treatment of WKF and discussion of the procedures in the context of the current literature. Read More

Sci Rep 2020 Jan 15;10(1):399. Epub 2020 Jan 15.

Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

The study aimed to analyze the radiographic and magnetic resonance imaging (MRI) findings that might predict the risk for adjacent segmental fractures (ASFs) when percutaneous vertebroplasty (PV) is used for the treatment of osteoporotic thoracolumbar fractures (OTFs). A total of 92 OTFs patients who underwent PV between January 2013 and January 2015 were retrospectively reviewed. The visual analog scale (VAS), Oswestry-Disability Index (ODI) and radiolographic measurements were assessed. Read More

Zhongguo Gu Shang 2019 Dec;32(12):1128-1133

Department of Orthopaedics, Hospital Affiliated to Xinyang Vocational and Technical College, Xinyang 464000, Henan, China;

Objective: To investigate the effect of bone cement dispersion and distribution on the clinical effect and the degree of pain reduction of percutaneous vertebroplasty(PVP) in the treatment of osteoporosis spinal fracture.

Methods: A retrospective analysis was made of 130 cases of osteoporotic spinal fractures admitted from August 2016 to April 2018, of which 114 cases were followed up completely. The VAS score, Oswestry disability index(ODI), kyphosis angle(Cobb angle), anterior column height and complications were analyzed. Read More

Medicine (Baltimore) 2019 Dec;98(50):e18413

Department of Orthopedic Surgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences.

Rationale: Chondrosarcoma of the sacrum is a highly unusual disease without standard curative managements yet. The objective of this study is to report a very rare case of chondrosarcoma of the sacrum successfully operated by percutaneous vertebroplasty. The management of these unique cases has yet to be well-documented. Read More

Medicine (Baltimore) 2019 Dec;98(50):e18217

Department of Orthopedics, The People's Hospital of Danyang, Danyang.

To evaluate the influence of various distributions of bone cement on the clinical efficacy of percutaneous kyphoplasty (PKP) in treating osteoporotic vertebrae compression fractures.A total of 201 OVCF patients (30 males and 171 females) who received PKP treatment in our hospital were enrolled in this study. According to the characteristic of cement distribution, patients were divided into 2 groups: group A ("H" shaped group), the filling pattern in vertebral body were 2 briquettes and connected with / without cement bridge; and group B ("O" shaped group), the filling pattern in vertebral body was a complete crumb and without any separation. Read More

World Neurosurg 2020 Mar 11;135:e435-e446. Epub 2019 Dec 11.

Department of Spine Surgery, Zhejiang Provincial People's Hospital, Hangzhou, Zhejiang, China; Hangzhou Medical College People's Hospital, Hangzhou, Zhejiang, China. Electronic address:

Introduction: Over the last several decades, both percutaneous kyphoplasty (PKP) and percutaneous vertebroplasty (PVP) have been used for pain relief in patients with osteoporotic vertebral compression fractures. The purpose of our study was to use citation analysis to identify and review the top 100 most-cited publications regarding PKP and PVP.

Methods: All databases of the Web of Science were searched using the keywords "kyphoplasty" and "vertebroplasty. Read More

Clin Exp Rheumatol 2019 Nov 20. Epub 2019 Nov 20.

Rheumatology Unit, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.

Objectives: To assess vertebral fracture (VFx) occurrence after percutaneous vertebroplasty (PVP) in patients with osteoporosis (OP), primary or secondary to chronic glucocorticoid (GC) therapy.

Methods: Prospective study of a 2-year follow-up.

Primary Outcome: proportion of patients with new VFx 24 months after PVP. Read More

Clin Interv Aging 2019 2;14:2095-2096. Epub 2019 Dec 2.

Department of Orthopaedic Surgery, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.

J Xray Sci Technol 2020 ;28(1):171-183

Departments of Musculoskeletal and Interventional Ultrasound, People's Hospital of Fengrun District, Hebei Province, China.

Objective: To evaluate application of a computed tomography (CT)-ultrasound fusion imaging technique to unilateral percutaneous vertebroplasty (PVP) for treating patients with osteoporotic thoracolumbar compression fracture.

Methods: Fourteen patients with osteoporotic thoracolumbar compression fractures were included, randomly divided into CT-ultrasound fusion imaging (n = 7) and traditional X-ray fluoroscopy groups (n = 7). Patients in the first group underwent unilateral PVP using real-time CT-ultrasound fusion imaging. Read More