43,842 results match your criteria Percutaneous Transluminal Coronary Angioplasty


Release of MMP-2 in the circulation of patients with acute coronary syndromes undergoing percutaneous coronary intervention: Role of platelets.

Thromb Res 2022 Jun 22;216:84-89. Epub 2022 Jun 22.

Department of Medicine and Surgery, Division of Internal and Cardiovascular Medicine, University of Perugia, Perugia, Italy. Electronic address:

Introduction: Matrix metalloproteinases (MMPs) of atherosclerotic tissue contribute to plaque rupture triggering acute coronary syndromes (ACS). Several MMPs, including MMP-2, are also contained in platelets and released upon activation. An increase in circulating levels of MMP-2 has been reported in patients undergoing percutaneous coronary interventions (PCI), but its time-course and origin remain unclear. Read More

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Perforation of Right Coronary Artery During Coronary Angioplasty: A Rare Complication.

Cureus 2022 May 24;14(5):e25278. Epub 2022 May 24.

Interventional Cardiology, People's Education Society Institute of Medical Sciences and Research, Kuppam, IND.

Coronary angioplasty procedure, also known as percutaneous transluminal coronary angioplasty (PTCA), is performed to restore blood flow across significantly blocked coronary vessels. Perforation of coronary vessels may occur rarely during the procedure or within 24 hours post-procedure and is considered a serious complication. We wish to share our experience of a case of perforation in the proximal and mid-portion of the right coronary artery (RCA) during coronary angioplasty. Read More

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Utility of sirolimus coated balloons in the peripheral vasculature - a review of the current literature.

CVIR Endovasc 2022 Jun 24;5(1):29. Epub 2022 Jun 24.

Department of Vascular Surgery, Singapore General Hospital, Singapore, Singapore.

Sirolimus-coated balloons (SCB) have demonstrated much promise as an alternative drug eluting device to the existing paclitaxel coated balloon platforms for the treatment of peripheral arterial disease (PAD). They have been well tested pre-clinically and have demonstrated anti-restenotic effects as well as clinical safety in its use for treatment of coronary artery disease. The existing approved SCBs have thus far demonstrated good short-term patency (12-months) and did not exhibit any major adverse events or device related shortcomings in its use for treatment of PAD. Read More

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Effect of PEGylation on the Drug Release Performance and Hemocompatibility of Photoresponsive Drug-Loading Platform.

Int J Mol Sci 2022 Jun 15;23(12). Epub 2022 Jun 15.

Division of Advanced Applied Physics, Institute of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei-shi, Tokyo 184-8588, Japan.

Coronary stenosis has been one of the most common heart diseases that drastically increases the risk of fatal disorders such as heart attack. Angioplasty using drug coated balloons (DCB) has been one of the most safe and promising treatments. To minimize the risk of thrombosis of such DCBs during intervention, a different approach that can secure high hemocompatibility under blood flow is necessary. Read More

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Biolimus-Coated Balloon in Small-Vessel Coronary Artery Disease: The BIO-RISE CHINA Study.

JACC Cardiovasc Interv 2022 Jun 25;15(12):1219-1226. Epub 2022 May 25.

General Hospital of Northern Theater Command, Shenyang, People's Republic of China. Electronic address:

Background: Drug-coated balloons are a safe and effective option for patients undergoing percutaneous coronary intervention, but prior randomized studies have exclusively used paclitaxel-coated devices.

Objectives: The aim of this study was to assess for the first time the safety and efficacy of a novel biolimus-coated balloon (BCB) in patients with small-vessel coronary disease.

Methods: In a prospective trial conducted at 10 centers in China, 212 patients with small-vessel native coronary disease (reference vessel diameter 2. Read More

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Early ischemic ST-segment and T-wave changes during balloon angioplasty.

J Electrocardiol 2022 Jun 16;73:87-95. Epub 2022 Jun 16.

Tampere University, Faculty of Medicine and Health Technology, Finnish Cardiovascular Research Center, Tampere, Finland.

Background: Acute coronary occlusion results in increased T-wave amplitude and ST-segment elevation in the ECG leads facing the ischemic region.

Material And Methods: We performed continuous ECG recording in 34 patients during balloon occlusion of the left anterior descending (LAD), left circumflex (LCx) and right coronary artery (RCA). Delta (Δ) ST and ΔT amplitudes were calculated by subtracting the preinflation values from the values measured during balloon inflation. Read More

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Lung transplantation and severe coronary artery disease: results from a single-centre experience.

Eur J Cardiothorac Surg 2022 Jun 15. Epub 2022 Jun 15.

Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

Objectives: The management of severe coronary artery disease at the time of lung transplantation remains a challenge. We analyzed the short- and long-term-outcomes of lung transplant recipients with severe coronary artery disease.

Methods: Records of adult patients transplanted at our institution between April 2010 and February 2021 were retrospectively reviewed. Read More

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Impact of post physiological assessment after treatment for de novo coronary lesions using drug-coated balloons.

Int J Cardiol 2022 Jun 6. Epub 2022 Jun 6.

Department of Cardiology, Toyooka Public Hospital, 1094, Tobera, Toyooka, Hyogo 668-8501, Japan.

Background: Acute physiological changes after balloon angioplasty are very important because of acute recoil and dissection. However, serial physiological assessments after drug-coated balloons (DCB) have not been investigated.

Methods: This prospective observational single-center study evaluated 50 lesions that underwent optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) with DCB and a 9-months angiographical and OCT follow-up. Read More

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Clinical Performance of a Paclitaxel Drug-Coated Balloon in Real-World Percutaneous Coronary Intervention Practice: The PEARL Registry.

J Invasive Cardiol 2022 Jun;34(6):E462-E468

Amphia Hospital, Department of Cardiology, Breda, The Netherlands.

Background: Randomized controlled trials for in-stent restenosis (ISR) and de novo lesions in small-diameter vessels have shown promising results, but data on DCB use in real-world practice are still scarce. The aim of the PEARL (Paclitaxel-Eluting Angioplasty Balloon in the Real-World) registry was to evaluate the safety and efficacy of a paclitaxel DCB in real-world percutaneous coronary intervention (PCI) practice.

Methods: Between 2014 and 2019, a total of 513 patients treated with the Protégé paclitaxel DCB (Wellinq) were prospectively included at 4 hospitals in the Netherlands. Read More

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Very Early Discharge of Patients with ST-Segment-Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention.

J Tehran Heart Cent 2021 Jul;16(3):113-118

Farshchian Heart Center, Hamadan University of Medical Sciences, Hamadan, Iran.

The discharge of uncomplicated patients with ST-segment-elevation myocardial infarction (STEMI) within 48 to 72 hours has been proven safe and feasible. The safety and feasibility of the very early discharge (≤48 h) of such patients, especially during the COVID-19 pandemic with limited bed availability and infection risk, have yet to be evaluated. In this cohort study on 108 patients with STEMI who presented to Farshchian Heart Center between February and May 2020, 30 patients received fibrinolysis and 78 were scheduled for emergent coronary angiography. Read More

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Electrocardiographic Changes in a Horse with Induced Myocardial Infarction.

Animals (Basel) 2022 May 16;12(10). Epub 2022 May 16.

Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Højbakkegaard Allé 5, 2630 Taastrup, Denmark.

During acute myocardial infarction (AMI), the ischemia and necrosis of the infarcted tissue result in local electrophysiological changes, which bring about deviations of the ST segment and T wave. In this case report, the aim was to investigate whether these changes could be detected with a 12-lead electrocardiogram (ECG) during acute occlusion of the coronary artery in a 15-year-old Standardbred mare (scheduled for euthanasia due to non-cardiac health problems). The left anterior descending (LAD) coronary artery was occluded using an angioplasty balloon catheter guided through the carotid artery. Read More

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[Surgical Removal of a Fractured Guide Wire for Coronary Angioplasty and Coronary Artery Bypass Grafting:Report of a Case].

Kyobu Geka 2022 Jun;75(6):467-471

Department of Cardiovascular Surgery, Hyogo Prefectural Amagasaki General Medical Center, Amagasaki, Japan.

Guide wire fracture is a rare, yet potentially life-threatening complication of percutaneous coronary intervention. A 65-years old man underwent emergent coronary angioplasty for myocardial ischemia. Percutaneous coronary intervention for the residual lesions of left anterior descending artery (LAD) was planned. Read More

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Promise of a Novel Bedside-to-Bench Paradigm: Can Percutaneous Coronary Intervention Proteomics Balloon Into Clinical Practice?

Arterioscler Thromb Vasc Biol 2022 Jul 26;42(7):865-867. Epub 2022 May 26.

From the Center for Interdisciplinary Cardiovascular Sciences (J.L.D., M.A., S.A.S.), Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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Influence of an Early Mobilization Protocol on the Autonomic Behavior of Patients Undergoing Percutaneous Transluminal Coronary Angioplasty.

Arq Bras Cardiol 2021 12;117(6):1161-1169

Universidade Federal do Triângulo Mineiro, Uberaba, MG - Brasil.

Background: Recurrence Plots (RP) enable a nonlinear analysis of Heart Rate Variability (HRV) and provide information on the Autonomic Nervous System (ANS).

Objectives: To evaluate whether early ambulation in patients undergoing Percutaneous Transluminal Coronary Angioplasty (PTCA) influences the quantitative and qualitative components of RP.

Methods: A total of 32 participants who underwent PTCA were divided into a Control Group (CG - no physical exercises) and an Early Ambulation Group (EAG - with physical exercises). Read More

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December 2021

Gangrene of the Foot After Coronary Artery Bypass Graft Surgery.

Perm J 2022 Apr 5;26(1):143-147. Epub 2022 Apr 5.

Department of Internal Medicine, Kaiser Permanente, Sacramento, CA, USA.

Coronary artery bypass grafting (CABG) is the most common surgery performed by cardiothoracic surgeons worldwide. Risks of CABG include neurological outcomes, deep vein thrombosis, renal or gastrointestinal injury, and death. Perioperatively, some patients may need intra-aortic balloon pump (IABP) use to help assist with cardiac function. Read More

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A Study of Estimated Glomerular Filtration Rate in Patients Undergoing Diagnostic or Interventional Coronary Contrast Procedures.

Indian J Nephrol 2022 Mar-Apr;32(2):132-137. Epub 2022 Mar 11.

Department of Nephrology, Aster Medcity, Kochi, Kerala, India.

Introduction: Angiographic procedures are underused in patients with chronic kidney disease (CKD), who present with acute coronary syndromes, due to risk of contrast-induced acute kidney injury (CI-AKI). In this study, we assessed the change in estimated glomerular filtration rate (eGFR) over 3 months following coronary procedures in CKD patients.

Methods: This observational study was done from July 2017 to January 2019 in patients undergoing elective coronary procedures with an eGFR <60 mL/min/1. Read More

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Overview of in-hospital outcomes in patients undergoing percutaneous coronary intervention with the revived directional coronary atherectomy.

Catheter Cardiovasc Interv 2022 May 20. Epub 2022 May 20.

Division of Cardiology, Tokai University School of Medicine, Isehara, Japan.

Objectives: We sought to provide clinical insights on the usage rate, indications, and in-hospital outcomes of the revived directional coronary atherectomy (DCA) catheter (Atherocut™) in a Japanese nationwide percutaneous coronary intervention (PCI) registry.

Background: Debulking devices such as the revived DCA catheter have become increasingly important in the era of complex PCI. However, little is known about PCI outcomes using a novel DCA catheter in contemporary real-world practice. Read More

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Transcatheter aortic valve implantation with a balloon-expandable prosthesis in a patient with single coronary artery: a case report.

Eur Heart J Case Rep 2022 May 3;6(5):ytac192. Epub 2022 May 3.

Division of Cardiovascular Surgery, Hokkaido Cardiovascular Hospital, 1-30 South27 West13, Chuo-ku, Sapporo City 064-8622, Japan.

Background: Single coronary artery is a rare coronary artery anomaly with an incidence of <0.03%. The coexistence of coronary artery anomalies with severe aortic stenosis is extremely rare. Read More

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ST-elevation myocardial infarction in a young patient with Duchenne's muscular dystrophy: a case report.

Eur Heart J Case Rep 2022 May 16;6(5):ytac184. Epub 2022 May 16.

Cardiology Department, Portsmouth Hospitals University NHS Trust, Portsmouth, UK.

Background: Duchenne's muscular dystrophy (DMD) is an X-linked muscular disease which is caused by the absence of dystrophin. This results in the death of muscle cells and cardiomyocytes and consequent substitution by fat and fibrous tissue. The clinical translation of this is muscle weakness and cardiomyopathy. Read More

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Evaluating the efficacy and safety of percutaneous coronary intervention (PCI) versus the optimal drug therapy (ODT) for stable coronary heart disease: a systematic review and meta-analysis.

J Thorac Dis 2022 Apr;14(4):1183-1192

Department of Cardiology, the First Affiliated Hospital of Soochow University, Suzhou, China.

Background: Many studies have reported potential benefits of percutaneous coronary intervention (PCI) versus optimal drug therapy (ODT) for patients with stable coronary heart disease but with inconsistent results. To examine this, an explicit systematic review and meta-analysis was conducted to compared the clinical outcomes of PCI and ODT in these patients.

Methods: The following terms were combined to search relative articles through databases PubMed, Cochrane Central Register of Controlled Trials, Embase, and Web of Science published from January 2010 to November 2021 according to Participants, Intervention, Control, Outcomes, Study (PICOS) criteria: "coronary heart disease", "stable coronary heart disease", "stable angina pectoris", "percutaneous coronary intervention", "PCI", "percutaneous transluminal coronary angioplasty", "drug therapy", "optimized drug treatment", and "optimized drug therapy". Read More

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Retrospective study of treatment with a drug-coated balloon alone is beneficial for ostial coronary lesions.

J Thorac Dis 2022 Apr;14(4):1203-1211

Department of Cardiology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.

Background: The effects of ostial coronary lesion (OCL) treatment with a drug-coated balloon (DCB) alone remain controversial. This retrospective study assessed the effectiveness and safety with DCB only strategy for OCL and the factors associated with target lesion revascularization (TLR) in these patients.

Methods: The study retrospectively included patients whom had OCLs treated with a paclitaxel-eluting DCB only strategy from 1 May 2014 to 1 May 2017. Read More

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Stretching and cutting after drilling. Vessel preparation following rotational atherectomy.

Catheter Cardiovasc Interv 2022 May;99(6):1750-1751

Cardiac Catheterization Laboratory, Tufts Medical Center, Boston, Massachusetts, USA.

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Unusual Cause of Acute Myocardial Infarction in a Patient With a History of Esophageal Cancer.

JACC Cardiovasc Interv 2022 Jun 11;15(12):e149-e150. Epub 2022 May 11.

Department of Cardiovascular Medicine, Kitasato University School of Medicine, Sagamihara, Japan.

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Feasibility and Safety of Drug-Coated Balloon-Only Angioplasty for De Novo Ostial Lesions of the Left Anterior Descending Artery: Two-Center Retrospective Study.

Front Cardiovasc Med 2022 25;9:874394. Epub 2022 Apr 25.

Heart Center and Beijing Key Laboratory of Hypertension, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.

Introduction: There is limited evidence regarding the effectiveness of drug-coated balloon (DCB) angioplasty in the percutaneous treatment of complex ostial coronary lesions. This study primarily aimed to explore the feasibility and safety of this innovative approach for ostial lesions in the left anterior descending artery (LAD).

Methods: Patients treated with paclitaxel DCB or second-generation drug-eluting stents (DES) were retrospectively enrolled from two large centers. Read More

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Hand-sewn expanded polytetrafluoroethylene valved conduit for right ventricular outflow tract reconstruction.

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2022 Jan;47(1):94-100

Department of Cardiovascular Surgery, Second Xiangya Hospital, Central South University, Changsha 410011.

Objectives: Due to the lack of large-sized pulmonary valved conduit products in clinical practice, hand-sewn expanded polytetrafluoroethylene (ePTFE) valved conduit has been used for right ventricular outflow tract (RVOT) reconstruction in many heart centers around the world. This study aims to summarize the early results of the ePTFE valved conduit and the sewing technology of the conduit in combination with the latest progress, and to provide a reference for the application of ePTFE valved conduit.

Methods: A total of 21 patients using ePTFE valved conduit for RVOT reconstruction in the Second Xiangya Hospital, Central South University from October 2018 to October 2020 were prospectively enrolled in this study. Read More

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January 2022

Use of Computed Tomography Coronary Calcium Score for Coronary Artery Disease Risk Stratification During Liver Transplant Evaluation.

J Clin Exp Hepatol 2022 Mar-Apr;12(2):319-328. Epub 2021 Aug 21.

Division of Cardiology, University of Arkansas for Medical Sciences, 4301 W. Markham Slot #567, Little Rock, AR, 70205, United States.

Background: End-stage liver disease (ESLD) is not considered a risk factor for atherosclerotic cardiovascular disease (ASCVD). However, lifestyle characteristics commonly associated with increased ASCVD risk are highly prevalent in ESLD. Emerging literature shows a high burden of asymptomatic coronary artery disease (CAD) in patients with ESLD and a high ASCVD risk in liver transplantation (LT) recipients. Read More

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A case report of pseudoaneurysm of coronary artery within a month of percutaneous coronary intervention.

Eur Heart J Case Rep 2022 May 21;6(5):ytac175. Epub 2022 Apr 21.

Department of Cardiology, Meditrina Hospital, Ambala 133001, Haryana, India.

Background: Coronary artery pseudoaneurysms (PSAs) are uncommon and have poorly understood natural history. Unlike true aneurysms, PSAs do not have all the three layers of the vessel in the aneurysmal wall. The PSAs are most commonly seen after an overzealous percutaneous coronary intervention (PCI) which causes damage to the vessel wall. Read More

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