1,939 results match your criteria Percutaneous Radiofrequency Ablation of Liver Tumors


Percutaneous Ablation of Hepatic Tumors at the Hepatocaval Confluence Using Irreversible Electroporation: A Preliminary Study.

Curr Oncol 2022 May 31;29(6):3950-3961. Epub 2022 May 31.

Department of Interventional Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Background: Tumors at the hepatocaval confluence are difficult to treat, either surgically or ablatively.

Methods: A retrospective longitudinal study on patients ineligible for thermal ablation who underwent computed tomography-guided IRE for hepatic tumors at the hepatocaval confluence was conducted. Factors analyzed included patient and tumor characteristics, IRE procedure details, treatment-related complications, and prognosis. Read More

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Clinical Outcomes of Radiological Treatment Modalities of Hepatocellular Carcinoma: A Single-Center Experience from Saudi Arabia.

Gulf J Oncolog 2022 May;1(39):56-62

King Abdulaziz Medical City, Jeddah, Saudi Arabia.

Background: Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver. Most patients with HCC are unsuitable for surgical therapies. Therefore, nonsurgical therapies play a central role in the management of this disease. Read More

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Conservative treatment of gastric perforation after microwave ablation of a hepatocellular carcinoma: Case report.

Medicine (Baltimore) 2022 Jun 3;101(22):e29195. Epub 2022 Jun 3.

Surgical Center Oranienburg, Oranienburg, Germany.

Rationale: Microwave ablation (MWA) has been proven to be an efficient and safe method for local tumor control of liver tumors. Reported complications are rare, but include liver abscess, hematoma, pleural effusion, and occasional thermal injury of the adjacent colon. Intestinal perforation usually requires immediate surgical treatment to prevent generalized peritonitis and sepsis. Read More

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Long-term outcomes following percutaneous microwave ablation for colorectal cancer liver metastases.

Int J Hyperthermia 2022 ;39(1):788-795

Radiology Department, AMEOS Klinikum Halberstadt GmbH, Halberstadt, Germany.

Purpose: To evaluate the overall survival (OS), local progression-free survival (PFS) and prognostic factors of patients with colorectal cancer liver metastases (CRLM) undergoing microwave ablation (MWA).

Method: A total of 132 patients were retrospectively enrolled who had been treated between 2010 and 2018. For the evaluation of survival rates, all patients were divided according to their indications (curative  = 57 and debulking (patients with additional non-target extrahepatic metastases)  = 75). Read More

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Stereotactic radiofrequency ablation as a valid first-line treatment option for hepatocellular adenomas.

Int J Hyperthermia 2022 ;39(1):780-787

Interventional Oncology-Microinvasive Therapy (SIP), Department of Radiology, Medical University Innsbruck, Innsbruck, Austria.

Objectives: This study aimed to assess the safety and efficacy of stereotactic radiofrequency ablation (SRFA) in patients with hepatocellular adenomas (HCA).

Methods: Retrospective analyses of all patients referred for SRFA treatment at our institution between January 2010 and October 2020 revealed 14 patients (10 women; mean age 34.4 [range, 17-73 years]) with 38 HCAs treated through 18 ablation sessions. Read More

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Biliary complications and efficacy after ablation of peribiliary tumors using irreversible electroporation (IRE) or radiofrequency ablation (RFA).

Int J Hyperthermia 2022 ;39(1):751-757

Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Objective: To evaluate the biliary complication rates and efficacy of peribiliary tumor ablation using irreversible electroporation (IRE) or radiofrequency ablation (RFA).

Material And Methods: This is a retrospective study of 42 consecutive patients with 44 peribiliary tumors (≤5 mm distance between the tumor margin and the primary or secondary bile duct). Data were collected between January 2014 and September 2020 from patients who underwent percutaneous liver ablation using IRE ( = 13) or RFA ( = 31). Read More

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Comparison of percutaneous microwave ablation and surgical resection for hepatocellular carcinoma in the caudate lobe.

J Cancer Res Ther 2022 Apr;18(2):378-383

Department of Interventional Ultrasound, The First Medical Center of Chinese PLA General Hospital, Beijing, China.

Background: This study aims to compare the clinical efficacy and safety between ultrasound (US)-guided percutaneous microwave ablation (MWA) assisted with a three-dimensional (3D) visualization preoperative planning system and surgical resection (SR) for hepatocellular carcinoma (HCC) in the caudate lobe.

Materials And Methods: Forty-nine patients diagnosed with caudate lobe HCC, who underwent US-guided percutaneous MWA (29 patients) or SR (20 patients), were enrolled between November 2005 and December 2018. Follow-up was performed at 1, 3, 6, 12, 18, 24, and 36 months after ablation or resection. Read More

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Comparison of percutaneous microwave ablation with radiofrequency ablation for hepatocellular carcinoma adjacent to major vessels: A retrospective study.

J Cancer Res Ther 2022 Apr;18(2):329-335

Department of Ultrasonic Intervention, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Changhai Rd, Shanghai, China.

Purpose: To compare the therapeutic efficacy and safety of percutaneous microwave ablation (MWA) with those of percutaneous radiofrequency ablation (RFA) for the treatment of hepatocellular carcinoma (HCC) adjacent to major vessels.

Methods: From January 2010 to April 2011, 78 patients with a single nodule, no >5 cm, adjacent to major vessels were enrolled in this study. Forty-four patients (forty-one men, three women; age range, 33-72 years) treated by MWA were compared with thirty-four patients (thirty-one men, three women; age range, 33-75 years) treated by RFA. Read More

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MR elastography is a good response parameter for microwave ablation liver tumors.

Eur J Radiol 2022 Jul 14;152:110360. Epub 2022 May 14.

Department of Trauma Surgery, Klinikum Rechts der Isar, Munich, Germany.

Objectives: To determine the response of hepatic tissue to percutaneous microwave ablation (MWA) of liver tumors via MR elastography in a clinical setting using MRI and MR elastography.

Methods: 51 Patients (28 m, 23f) underwent MWA of liver tumors (HCC: 20, metastasis: 31) and received MRI and MR elastography immediately before and 24 h after MWA. Retrospective analysis included pre- and post-ablative tumor extent, T1/T2 mapping and stiffness values as well as the duration and energy dose of the MWA session. Read More

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Robotic laser position versus freehand in CT-guided percutaneous microwave ablation for single hepatocellular carcinoma (diameter < 3 cm): a preliminary study.

Int J Hyperthermia 2022 ;39(1):725-732

Department of Oncology, The People's Hospital of Jianyang City, Chengdu, China.

Purpose: To compare the accuracy and safety of robotic laser position (RLP) versus freehand for antenna CT-guided microwave ablation (MWA) of single hepatocellular carcinoma (HCC) (diameter < 3 cm).

Materials And Methods: This retrospective study was conducted between May 2020 and June 2021. A total of 40 patients with early HCC who underwent CT-guided MWA were divided into two groups: a freehand group ( = 20) and a RLP group ( = 20). Read More

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Adapting the Utility of Lipiodol CT in Treating Small Hepatocellular Carcinoma.

J Clin Exp Hepatol 2022 Mar-Apr;12(2):664-668. Epub 2021 Jul 30.

Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi, India.

Introduction: Multiphase MRI liver is the gold-standard imaging modality for staging hepatocellular carcinoma (HCC) in patients with cirrhosis. Often, small HCCs diagnosed on multiphase MRI are occult on B-mode ultrasound and multiphase CT (MPCT) and thus pose a challenge for loco-regional therapy. We adapted the technique of lipiodol CT in treating two such patients of small HCC. Read More

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Repeat hepatic resection versus percutaneous ablation for the treatment of recurrent hepatocellular carcinoma: meta-analysis.

BJS Open 2022 03;6(2)

Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.

Background: The efficacy of repeat hepatic resection (rHR) in the treatment of recurrent hepatocellular carcinoma compared with radiofrequency or microwave ablation after resection of the primary tumour remains controversial. A systematic review and meta-analysis were performed to compare the safety and efficacy of these procedures.

Methods: PubMed, Embase, Scopus, Cochrane Library, and China National Knowledge Infrastructure databases were systematically searched to identify related studies published before 10 October 2021. Read More

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Thermal ablation in the management of oligometastatic colorectal cancer.

Int J Hyperthermia 2022 ;39(1):627-632

Departement d'anesthésie, de chirurgie, et de radiologie interventionnelle, Gustave Roussy, Villejuif, France.

Purpose: To review available evidence on thermal ablation of oligometastatic colorectal cancer.

Methods: Technical and cancer specific considerations for percutaneous image-guided thermal ablation of oligometastatic colorectal metastases in the liver and lung were reviewed. Ablation outcomes are compared to surgical and radiation therapy literature. Read More

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Minimally invasive surgery versus percutaneous radiofrequency ablation for early-stage hepatocellular carcinoma: Results from a high-volume liver surgery center in East Asia.

Surg Oncol 2022 Jun 19;42:101769. Epub 2022 Apr 19.

Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Background & Aims: The outcomes of minimally invasive surgery (MIS) vs. percutaneous radiofrequency ablation (RFA) in treating early-stage hepatocellular carcinoma (HCC) remain inconclusive. This study thus aimed to compare the outcomes of both treatments for early-stage HCCs. Read More

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Contemporary evidence on colorectal liver metastases ablation: toward a paradigm shift in locoregional treatment.

Int J Hyperthermia 2022 ;39(1):649-663

Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Image-guided percutaneous ablation techniques represent an attractive local therapy for the treatment of colorectal liver metastases (CLM) given its low risk of severe complications, which allows for early initiation of adjuvant therapies and spare functional liver parenchyma, allowing repeated treatments at the time of recurrence. However, ablation does not consistently achieve similar oncological outcomes to surgery, with the latter being currently considered the first-line local treatment modality in international guidelines. Recent application of computer-assisted ablation planning, guidance, and intra-procedural response assessment has improved percutaneous ablation outcomes. Read More

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Risk of pleural and diaphragmatic complications following percutaneous radiofrequency ablation of basal lung nodules.

Diagn Interv Imaging 2022 Jun 15;103(6):324-326. Epub 2022 Apr 15.

Department of Radiology, Hôpital Cochin, AP-HP.Centre, 75014 Paris, France; Université Paris Cité, Faculté de Médecine, 75006 Paris, France. Electronic address:

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Multi-stage puncture path planning algorithm of ablation needles for percutaneous radiofrequency ablation of liver tumors.

Comput Biol Med 2022 06 9;145:105506. Epub 2022 Apr 9.

Software College, Northeastern University, No.195, Chuangxin Road, Hunnan District, Shenyang, 110169, Liaoning, China.

This paper designs a multi-stage puncture path planning algorithm of ablation needles for percutaneous radiofrequency ablation of liver tumors, in order to guide or assist clinicians automatically plan the puncture path of ablation needle, and improve the safety and effectiveness of percutaneous radiofrequency ablation for liver cancer. Firstly, the initial feasible puncture paths satisfying the hard constraints are obtained by quantifying different clinical multi-constraint conditions. Then, according to the soft constraints, the risk index of puncture path is designed to realize the first-stage path planning. Read More

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Risk of intra-abdominal seeding after laparoscopic-assisted thermal ablation of exophytic hepatocellular carcinoma tumors.

Surg Endosc 2022 Mar 29. Epub 2022 Mar 29.

Department of Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA.

Background: Laparoscopic-assisted thermal ablation has been used successfully to treat early hepatocellular carcinoma (HCC) tumors, defined as < 3 cm in diameter. This approach allows for ablation of tumors located in areas of the liver that are otherwise inaccessible for a percutaneous approach. Thermal ablation of exophytic tumors remains controversial due to a reported increased risk of tumor seeding of the abdominal cavity and incomplete ablation. Read More

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Percutaneous ultrasound-guided radiofrequency ablation for patients with liver metastasis from pancreatic adenocarcinoma.

Int J Hyperthermia 2022 ;39(1):517-524

Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Ultrasound, Peking University Cancer Hospital & Institute, Beijing, China.

Objective: To analyze the survival outcomes and prognostic factors of radiofrequency ablation (RFA) for pancreatic adenocarcinoma liver metastasis (PALM).

Methods: Between January 2010 and July 2021, 20 patients (13 males) with an average age of 58.9 ± 11. Read More

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Prognostic Role of Albumin-Bilirubin Grade in Hepatocellular Carcinoma After Ultrasound-guided Percutaneous Radiofrequency Ablation: A Single-center Experience Over a Decade.

Surg Laparosc Endosc Percutan Tech 2022 Jun 1;32(3):350-356. Epub 2022 Jun 1.

Department of Medical Ultrasonics, Institute of Diagnostic and Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

Background: The albumin-bilirubin (ALBI) grade has been proposed to evaluate liver function and predict prognosis in patients with hepatocellular carcinoma (HCC). Data are scarce in terms of the clinical application of ALBI score in patients with HCC undergoing radiofrequency ablation (RFA). The current study sought to assess the prognostic efficacy of ALBI grade in early-stage HCC after RFA. Read More

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Ultrasound-guided percutaneous radiofrequency ablation in treatment of neuroendocrine tumor liver metastases:a single-center experience.

Int J Hyperthermia 2022 ;39(1):497-503

Department of Medical Ultrasound, Division of Interventional Ultrasound, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Purpose: To investigate the local tumor control of ultrasound-guided percutaneous radiofrequency ablation (RFA) in treating neuroendocrine tumor liver metastases (NETLM).

Materials And Methods: From March 2011 to December 2020, 23 patients with 39 NETLM treated with percutaneous RFA were studied. The study assessed the therapeutic outcomes after RFA, including the rates of technical success, technical efficacy, major complications, local tumor progression (LTP) and overall survival. Read More

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Software-based assessment of tumor margins after percutaneous thermal ablation of liver tumors: A systematic review.

Diagn Interv Imaging 2022 May 1;103(5):240-250. Epub 2022 Mar 1.

Department of Radiology, St-Eloi University Hospital, 34090, Montpellier, France. Electronic address:

Purpose: The purpose of this study was to make a systematic review of clinical studies evaluating software-based tumor margin assessment after percutaneous thermoablation (PTA) of liver tumors.

Materials And Methods: A systematic literature search was performed through Pubmed/MEDLINE, Embase and the Cochrane Library. Original studies published in English that reported on software-based assessment of ablation margins (AM) following PTA of liver tumors were selected. Read More

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Real-time arteriography-directed percutaneous microwave ablation for small or poorly characterized hepatic lesions using hybrid Angio-CT.

Abdom Radiol (NY) 2022 04 26;47(4):1457-1463. Epub 2022 Feb 26.

Department of Radiology, Medical Center, University of Chicago, University of Chicago, Chicago, IL, 60637, USA.

Purpose: To report the utility of real-time arteriography-directed percutaneous MWA (rad-pMWA) in a hybrid angiography-computed tomography (Angio-CT) suite to treat small or inconspicuous hepatic tumors on non-contrast CT.

Method: This single-center retrospective cohort included 15 consecutive patients who underwent rad-pMWA (6 HCC, 4 mCRC, 4 NET, and 1 cholangiocarcinoma). The median longest axial diameter of treated tumors was 1. Read More

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New approach for hepatocellular carcinoma treatment.

J Med Life 2022 Jan;15(1):138-143

Department of Surgery, Sfanta Maria Clinical Hospital, Bucharest, Romania.

Hepatocellular carcinoma (HCC) is the fifth most common cancer, with an increasing incidence in recent years. The prognosis is unfavorable, representing the third most frequent cause of cancer-related death worldwide. This is because it generally develops in patients with pre-existing liver pathology, thus limiting therapeutic options. Read More

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January 2022

Percutaneous Microwave Ablation for the Management of Hepatocellular Carcinoma in Transfusion-Dependent Beta-Thalassemia Patients.

Cardiovasc Intervent Radiol 2022 05 15;45(5):709-711. Epub 2022 Feb 15.

2nd Department of Radiology, Medical School, University General Hospital "ATTIKON", National and Kapodistrian University of Athens, 1 Rimini Str, Haidari, 12462, Athens, Greece.

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Percutaneous Ablation for Colorectal Metastases in Australia: Are Patients Missing Out?

Cardiovasc Intervent Radiol 2022 05 15;45(5):712-714. Epub 2022 Feb 15.

Department of Radiology, Alfred Health, 55 Commercial Road, Melbourne, VIC, 3004, Australia.

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Contrast-enhanced ultrasound features predict the prognosis of percutaneous microwave ablation of intrahepatic cholangiocarcinoma.

Br J Radiol 2022 May 9;95(1133):20211379. Epub 2022 Feb 9.

Department of Interventional Ultrasound, The Fifth Medical Center of PLA General Hospital, Beijing, China.

Objective: To evaluate the prognostic effect of pre-operative contrast-enhanced ultrasound (CEUS) features on intrahepatic cholangiocarcinoma (ICC) after percutaneous microwave ablation (MWA).

Methods: A total of ICC 29 patients (average age 56.34 ± 9. Read More

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Suppression of Local Tumor Progression in Perivascular Hepatocellular Carcinoma by Combination Therapy with Radiofrequency Ablation and Percutaneous Ethanol Injection: A Propensity Score Matching Analysis.

Oncology 2022 3;100(6):303-312. Epub 2022 Feb 3.

Department of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.

Background And Aims: Radiofrequency ablation (RFA) has replaced percutaneous ethanol injection (PEI) as the treatment of choice for hepatocellular carcinoma (HCC); however, control of local tumor progression (LTP) remains a challenge in perivascular HCC. The aim of this study was to determine whether PEI added to RFA can reduce the LTP rate in perivascular HCC patients.

Methods: We retrospectively analyzed 167 patients, with 197 newly diagnosed HCC nodules with peritumoral vessels, who underwent either RFA plus PEI or RFA monotherapy as the first-line treatment between June 2001 and April 2015. Read More

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Medical Treatment for Hepatocellular Carcinoma in Japan.

J Nippon Med Sch 2022 May 25;89(2):154-160. Epub 2022 Jan 25.

Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School Hospital.

Liver cancer, including hepatocellular carcinoma (HCC), is the fifth most common cause of cancer deaths in Japan. The main treatment options for HCC are surgical resection, liver transplantation, radiofrequency ablation (RFA), transarterial chemoembolization (TACE), and systemic chemotherapy. Here, recent medical treatments for HCC, including surgery, percutaneous ablation, transcatheter arterial chemoembolization/transcatheter arterial embolization, and drug therapy, are reviewed with a focus on Japan. Read More

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Combined Transarterial Chemoembolization with Microwave Ablation Microwave Alone for Treatment of Medium Sized Hepatocellular Carcinoma.

Curr Cancer Drug Targets 2022 ;22(1):77-85

Hepatology, Gastroenterology and Infectious Diseases Department, Faculty of Medicine, Benha University, Benha, Egypt.

Background & Aims: Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancer-related deaths. The only definitive treatment for both HCC and cirrhosis is liver transplantation, but long wait times in some regions and a relatively fixed number of donor organs negatively impact access to liver transplantation. The aim of the work was to evaluate and compare the short outcome of patients with medium-sized HCC who will undergo percutaneous microwave ablation (MWA) alone and in combination with TACE. Read More

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