Search Our Scientific Publications & Authors

Diagn Interv Radiol 2022 Jun 22. Epub 2022 Jun 22.

Diagnostic and Interventional Radiology, Saarland University Medical Center, Hamburg, Germany.

To report on complication management in a 58-year-old woman referred for transjugular biopsy for evaluation of an unknown liver disease. After an initial uneventful biopsy procedure, the patient complained of severe upper abdominal pain. Laboratory test revealed increasing liver enzymes. Read More

World J Hepatol 2022 May;14(5):1038-1046

Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Prague 14021, Czech Republic.

Background: Transjugular intrahepatic portosystemic shunt (TIPS) is a method used to decrease portal hypertension. Biliary stricture is the rarest of the complications associated with this procedure with only 12 cases previously reported in the literature. None of these cases have documented the resolution of biliary stenosis induced by a stent graft. Read More

Rev Esp Enferm Dig 2022 Jun 15. Epub 2022 Jun 15.

Radiology, Binzhou Medical University, China.

A 72-year-old man was referred to us for evaluation of asymptomatic masses in the liver that had been detected on ultrasonography performed during a physical screening. The level of neuron-specific enolase was elevated (56.97 ng/mL; normal level, 15. Read More

Obes Surg 2022 Jun 14. Epub 2022 Jun 14.

Department of Endocrinology and Metabolism, Obesity Unit, Hospital Universitario La Paz, Paseo de La Castellana, 261, 28046, Madrid, Spain.

Background: In patients with clinically severe obesity, metabolic associated fatty liver disease (MAFLD) and steatohepatitis are highly prevalent. There is a lack of prospective studies evaluating the impact of bariatric surgery (BS) on MAFLD using both noninvasive and histological criteria. The present study aims to assess the impact of BS on MAFLD using histological and biochemical criteria. Read More

Cureus 2022 May 4;14(5):e24726. Epub 2022 May 4.

Pediatric Gastroenterology, Rutgers University New Jersey Medical School, Newark, USA.

Objectives To present a nationwide retrospective analysis of the sequelae and aftereffects of different liver biopsy methods in the care of pediatric patients with biliary atresia. Methods The National Inpatient Sample 2001-2013 database was queried for a primary diagnosis of biliary atresia and stratified based on biopsy type including percutaneous, surgical, laparoscopic, and transjugular. Patient demographics, length of stay, hospital costs, type of treatment, and mortality were compared by biopsy type. Read More

Medicine (Baltimore) 2022 Jun 3;101(22):e29195. Epub 2022 Jun 3.

Surgical Center Oranienburg, Oranienburg, Germany.

Rationale: Microwave ablation (MWA) has been proven to be an efficient and safe method for local tumor control of liver tumors. Reported complications are rare, but include liver abscess, hematoma, pleural effusion, and occasional thermal injury of the adjacent colon. Intestinal perforation usually requires immediate surgical treatment to prevent generalized peritonitis and sepsis. Read More

World J Clin Cases 2022 May;10(13):4273-4279

Department of Radiology, Lanzhou University The Second Hospital, Lanzhou 730030, Gansu Province, China.

Background: Perivascular epithelioid cell tumor (PEComa) is a mesenchymal tumor with histologic and immunophenotypic characteristics of perivascular epithelioid cells, has a low incidence, and can involve multiple organs. PEComa originating in the liver is extremely rare, with most cases being benign, and only a few cases are malignant. Good outcomes are achieved with radical surgical resection, but there is no effective treatment for some large tumors and specific locations that are contraindicated for surgery. Read More

Int J Hyperthermia 2022 ;39(1):788-795

Radiology Department, AMEOS Klinikum Halberstadt GmbH, Halberstadt, Germany.

Purpose: To evaluate the overall survival (OS), local progression-free survival (PFS) and prognostic factors of patients with colorectal cancer liver metastases (CRLM) undergoing microwave ablation (MWA).

Method: A total of 132 patients were retrospectively enrolled who had been treated between 2010 and 2018. For the evaluation of survival rates, all patients were divided according to their indications (curative  = 57 and debulking (patients with additional non-target extrahepatic metastases)  = 75). Read More

Int J Surg Case Rep 2022 May 18;94:107087. Epub 2022 Apr 18.

Tam Anh Hospital, Hanoi, Viet Nam; School of Medicine and Pharmacy, Vietnam National University, Hanoi, Viet Nam.

Background: Angiomyolipoma (AML) is a solid benign neoplasm with mesenchymal features. The clinical signs and symptoms of hepatic angiomyolipoma are nonspecific, and treatment strategy is variable.

Presentation: A 35-years-old male patient has admitted to the hospital with symptoms of severe anemia. Read More

Int J Hyperthermia 2022 ;39(1):780-787

Interventional Oncology-Microinvasive Therapy (SIP), Department of Radiology, Medical University Innsbruck, Innsbruck, Austria.

Objectives: This study aimed to assess the safety and efficacy of stereotactic radiofrequency ablation (SRFA) in patients with hepatocellular adenomas (HCA).

Methods: Retrospective analyses of all patients referred for SRFA treatment at our institution between January 2010 and October 2020 revealed 14 patients (10 women; mean age 34.4 [range, 17-73 years]) with 38 HCAs treated through 18 ablation sessions. Read More

United European Gastroenterol J 2022 Jun 2. Epub 2022 Jun 2.

Department for Biomedical Research DBMR, University of Bern, Bern, Switzerland.

Objectives: Percutaneous liver biopsy is an essential diagnostic investigation in hepatology. Among complications, which are rare, bleeding is the most feared. Many patients scheduled for a liver biopsy are taking aspirin. Read More

World J Hepatol 2022 Apr;14(4):696-707

Postgraduate Program in Tropical Medicine, Center of Health Sciences, Universidade Federal de Pernambuco, Recife 50670-901, Pernambuco, Brazil.

Schistosomiasis mansoni is a neglected disease and key public health problem, mainly due to its high prevalence, the scarcity of public policies, and the severity of some clinical forms. Periportal fibrosis (PPF) is the commonest complication of chronic schistosomiasis mansoni and its diagnosis requires different techniques. Even though wedge biopsy of the liver is considered the gold standard, it is not justified in non-surgical patients, and percutaneous liver biopsy may be informative but does not have sufficient sensitivity. Read More

J Cancer Res Ther 2022 Apr;18(2):329-335

Department of Ultrasonic Intervention, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Changhai Rd, Shanghai, China.

Purpose: To compare the therapeutic efficacy and safety of percutaneous microwave ablation (MWA) with those of percutaneous radiofrequency ablation (RFA) for the treatment of hepatocellular carcinoma (HCC) adjacent to major vessels.

Methods: From January 2010 to April 2011, 78 patients with a single nodule, no >5 cm, adjacent to major vessels were enrolled in this study. Forty-four patients (forty-one men, three women; age range, 33-72 years) treated by MWA were compared with thirty-four patients (thirty-one men, three women; age range, 33-75 years) treated by RFA. Read More

Children (Basel) 2022 May 9;9(5). Epub 2022 May 9.

Department of Radiology & Pediatric Radiology, Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.

Aim: To evaluate the feasibility of multiple ultrasound markers for the non-invasive characterization of fibrosis, inflammation and steatosis in the liver in pediatric patients.

Materials And Methods: The quantitative ultrasound measures shear wave elastography (SWE), shear wave dispersion (SWD) and attenuation imaging (ATI) were compared and correlated with percutaneous liver biopsies and corresponding measures in a control cohort.

Results: The median age of the 32 patients was 12. Read More

Eur J Radiol 2022 Jul 14;152:110360. Epub 2022 May 14.

Department of Trauma Surgery, Klinikum Rechts der Isar, Munich, Germany.

Objectives: To determine the response of hepatic tissue to percutaneous microwave ablation (MWA) of liver tumors via MR elastography in a clinical setting using MRI and MR elastography.

Methods: 51 Patients (28 m, 23f) underwent MWA of liver tumors (HCC: 20, metastasis: 31) and received MRI and MR elastography immediately before and 24 h after MWA. Retrospective analysis included pre- and post-ablative tumor extent, T1/T2 mapping and stiffness values as well as the duration and energy dose of the MWA session. Read More

Liver Transpl 2022 May 21. Epub 2022 May 21.

Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

We perform routine preprocurement image-guided percutaneous liver biopsies on potential donation after circulatory death (DCD) liver donors. The purpose of this study was to examine the impact of preprocurement liver biopsy on the use of livers from DCD donors. We retrospectively reviewed demographics, liver histology, and disposition of DCD liver donors within a single organ procurement organization (OPO) who underwent preprocurement liver biopsy from January 2000 through December 2019. Read More

Nephrol Dial Transplant 2022 May 19. Epub 2022 May 19.

Civil Hospital of Castelfranco Veneto, Nephrology and Dialysis Unit, Castelfranco Veneto, Italy.

Background: The known risks and benefits of native kidney biopsies are mainly based on the findings of retrospective studies. The aim of this multicentre prospective study was to evaluate the safety of percutaneous renal biopsies and quantify biopsy-related complication rates in Italy.

Methods: The study examined the results of native kidney biopsies performed in 54 Italian nephrology centres between 2012 and 2020. Read More

Int J Hyperthermia 2022 ;39(1):725-732

Department of Oncology, The People's Hospital of Jianyang City, Chengdu, China.

Purpose: To compare the accuracy and safety of robotic laser position (RLP) versus freehand for antenna CT-guided microwave ablation (MWA) of single hepatocellular carcinoma (HCC) (diameter < 3 cm).

Materials And Methods: This retrospective study was conducted between May 2020 and June 2021. A total of 40 patients with early HCC who underwent CT-guided MWA were divided into two groups: a freehand group ( = 20) and a RLP group ( = 20). Read More

J Gastroenterol Hepatol 2022 May 5. Epub 2022 May 5.

H. H. Chao Comprehensive Digestive Disease Center, University of California, Los Angeles, California, USA.

Background And Aim: The portal pressure gradient (PPG) is a useful predictor of portal hypertension (PH) related complications. We previously showed the feasibility and safety of endoscopic ultrasound guided PPG measurement (EUS-PPG). Now EUS-guided liver biopsy (EUS-bx) has been shown to be a safe and effective alternative to percutaneous or Interventional Radiology-guided liver biopsy for the diagnosis of chronic liver disease (CLD). Read More

Dig Liver Dis 2022 06 1;54(6):737-746. Epub 2022 May 1.

Department of Digestive Oncology, CHU Reims, Reims, France.

Introduction: Desmoid tumor (DT) of the abdomen is a challenging and rare disease. The level of evidence available to document their treatment is relatively low, however, recent publications of prospective studies have allowed to precise their management.

Methods: This document is a summary of the French intergroup guidelines realized by all French medical and surgical societies involved in the management of DT located in the abdomen or associated with adenomatous polyposis. Read More

J Vasc Interv Radiol 2022 Apr 30. Epub 2022 Apr 30.

Division of Surgery, DAICIM Foundation, Buenos Aires, Argentina; Division of Surgery, University of Buenos Aires, Buenos Aires, Argentina; Division of Surgery, Percutaneous Surgery, IHU IRCAD, University of Strasbourg, France.

Purpose: To determine risk factors (RFs) for hemorrhagic adverse events (AEs) associated with percutaneous transhepatic biliary drainage (PTBD) and to develop a risk assessment model.

Materials And Methods: This was a multicenter, prospective, observational study between 2015 and 2020. Adults with an indication for PTBD were included. Read More

Front Med (Lausanne) 2022 15;9:858219. Epub 2022 Apr 15.

Department of Hepatology, The First Hospital of Jilin University, Changchun, China.

Primary intrahepatic rhabdomyosarcoma is an extremely rare malignant tumor. Here, we describe a case of embryonal rhabdomyosarcoma of the liver in a 7-year-old boy without any symptoms. Serologically, the patient showed abnormal levels of serum tumor markers and liver function. Read More

Malays J Pathol 2022 Apr;44(1):83-92

Alicante General University Hospital, Alicante Institute for Health and Biomedical Research (ISABIAL), Pathology Department, PintorBaeza, 12, 03010, Alicante, Spain.

Introduction: Data on pathological changes in COVID-19 are scarce. The aim of this study was to describe the histopathological and virological findings of postmortem biopsies, and the existing clinical correlations, in people who died of COVID-19.

Materials And Methods: We performed postmortem needle core biopsies of the chest in 11 people who died of COVID-19 pneumonia. Read More

BJS Open 2022 03;6(2)

Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.

Background: The efficacy of repeat hepatic resection (rHR) in the treatment of recurrent hepatocellular carcinoma compared with radiofrequency or microwave ablation after resection of the primary tumour remains controversial. A systematic review and meta-analysis were performed to compare the safety and efficacy of these procedures.

Methods: PubMed, Embase, Scopus, Cochrane Library, and China National Knowledge Infrastructure databases were systematically searched to identify related studies published before 10 October 2021. Read More

Int J Hyperthermia 2022 ;39(1):627-632

Departement d'anesthésie, de chirurgie, et de radiologie interventionnelle, Gustave Roussy, Villejuif, France.

Purpose: To review available evidence on thermal ablation of oligometastatic colorectal cancer.

Methods: Technical and cancer specific considerations for percutaneous image-guided thermal ablation of oligometastatic colorectal metastases in the liver and lung were reviewed. Ablation outcomes are compared to surgical and radiation therapy literature. Read More

Surg Oncol 2022 Jun 19;42:101769. Epub 2022 Apr 19.

Division of Hepatogastroenterology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Background & Aims: The outcomes of minimally invasive surgery (MIS) vs. percutaneous radiofrequency ablation (RFA) in treating early-stage hepatocellular carcinoma (HCC) remain inconclusive. This study thus aimed to compare the outcomes of both treatments for early-stage HCCs. Read More

Int J Hyperthermia 2022 ;39(1):649-663

Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Image-guided percutaneous ablation techniques represent an attractive local therapy for the treatment of colorectal liver metastases (CLM) given its low risk of severe complications, which allows for early initiation of adjuvant therapies and spare functional liver parenchyma, allowing repeated treatments at the time of recurrence. However, ablation does not consistently achieve similar oncological outcomes to surgery, with the latter being currently considered the first-line local treatment modality in international guidelines. Recent application of computer-assisted ablation planning, guidance, and intra-procedural response assessment has improved percutaneous ablation outcomes. Read More

Cardiovasc Intervent Radiol 2022 Jul 21;45(7):1010-1018. Epub 2022 Apr 21.

Diagnostic and Interventional Radiology, Hannover Medical School, Hanover, Germany.

Purpose: To determine the magnetic resonance (MR) sequences best suited for the assessment of ablation zones after radiofrequency ablation (RFA).

Methods: Three percutaneous MR-guided RFA of the liver were performed on three swine. Four pre-contrast and two hepatobiliary post-contrast sequences were obtained after ablation. Read More

Comput Biol Med 2022 06 9;145:105506. Epub 2022 Apr 9.

Software College, Northeastern University, No.195, Chuangxin Road, Hunnan District, Shenyang, 110169, Liaoning, China.

This paper designs a multi-stage puncture path planning algorithm of ablation needles for percutaneous radiofrequency ablation of liver tumors, in order to guide or assist clinicians automatically plan the puncture path of ablation needle, and improve the safety and effectiveness of percutaneous radiofrequency ablation for liver cancer. Firstly, the initial feasible puncture paths satisfying the hard constraints are obtained by quantifying different clinical multi-constraint conditions. Then, according to the soft constraints, the risk index of puncture path is designed to realize the first-stage path planning. Read More

J Vis Exp 2022 03 25(181). Epub 2022 Mar 25.

Gastroenterology and Hepatology Unit, Department of Medicine, Faulty of Medicine, University of Malaya.

Patients with unresectable malignant biliary obstruction often require biliary drainage to decompress the biliary system. Endoscopic Retrograde Cholangiopancreatography (ERCP) is the primary biliary drainage method whenever possible. Percutaneous Transhepatic Biliary Drainage (PTBD) is used as a salvage method if ERCP fails. Read More