Search Our Scientific Publications & Authors

Radiol Bras 2021 May-Jun;54(3):165-170

Laboratório de Pesquisa em Imagens Médicas (Labimed) da Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Porto Alegre, RS, Brazil.

Objective: To evaluate variables affecting the need for analgesia after ultrasound-guided percutaneous liver biopsy performed on an outpatient basis.

Materials And Methods: This was a retrospective analysis of 1,042 liver biopsies performed between 2012 and 2018. The data collected included the age and sex of the patient, as well as self-reported pain in the recovery room, the pain treatment used, the indication for the biopsy, and the lobe punctured. Read More

Nihon Shokakibyo Gakkai Zasshi 2021 ;118(6):562-570

Department of Gastroenterological Medicine, South-nara General Medical Center.

Contrast medium-enhanced computed tomography revealed a mass in the liver of a 65-year-old man. The edge but not the center of the mass was enhanced. Ultrasonography-guided percutaneous needle biopsy revealed the diagnosis of angiosarcoma of the liver, and it was treated with chemotherapy. Read More

Cureus 2021 May 6;13(5):e14880. Epub 2021 May 6.

Department of Medicine, Lady Hardinge Medical College, Delhi, IND.

Immune hemolytic anemia is very rarely associated with chronic liver disease. Diagnosis is often complicated in critically ill patients, where an etiological diagnosis can be elusive, especially in routine health care settings. A 48-year-old man presented with jaundice for three months. Read More

Pol J Radiol 2021 26;86:e239-e245. Epub 2021 Apr 26.

Gleneagle Global Hospital, India.

Background: Liver biopsy is a widely used, safe diagnostic tool utilised by clinicians for the histopathological assessment of the liver. Our study aims to report our experience in patients who underwent ultrasound-guided plugged percutaneous liver biopsy in a tertiary care hospital in India.

Material And Methods: The Institutional Ethical Review Board approved this retrospective study, and informed consent was obtained from all the patients. Read More

Intern Med 2021 1;60(11):1657-1664. Epub 2021 Jun 1.

Division of Gastroenterology, Department of Internal Medicine, Showa University Fujigaoka Hospital, Japan.

Objective Both a percutaneous biopsy and endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) have been widely performed for liver tumors. However, no studies have compared these two biopsy methods. Method A retrospective study was conducted using medical records for patients who underwent a liver tumor biopsy from 2012 to 2019. Read More

J Vasc Interv Radiol 2021 May 28. Epub 2021 May 28.

Division of Vascular & Interventional Radiology, Department of Radiology, Duke University Medical Center, Durham, NC 27710. Electronic address:

Purpose: To report initial clinical experience with intravascular ultrasound guided transvenous biopsy (IVUS-TVB) for perivascular target lesions in the abdomen and pelvis using side-viewing phased array intracardiac echocardiography catheters.

Materials And Methods: In this single institution, retrospective study 50 IVUS-TVB procedures were performed in 48 patients for targets close to the inferior vena cava or iliac veins deemed difficult to access by conventional percutaneous needle biopsy (PNB). In all procedures side-viewing phased array intracardiac echocardiography IVUS catheters and transjugular liver biopsy sets were inserted through separate jugular or femoral vein access sheaths, and 18-gauge core needle biopsy specimens were obtained under real-time IVUS guidance. Read More

Front Oncol 2021 14;11:678490. Epub 2021 May 14.

Department of Radiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Purpose: To evaluate the efficacy and safety of percutaneous radiofrequency ablation (RFA) for subcapsular colorectal cancer liver metastases (CLMs).

Materials And Methods: With the approval of the Institutional Review Board, the clinical data of CLM patients who underwent percutaneous RFA for the first time from August 2010 to August 2020 were continuously collected. All CLMs were divided into subcapsular and non-capsular groups. Read More

Ann Hepatobiliary Pancreat Surg 2021 May;25(2):215-220

Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Backgrounds/aims: Angiomyolipoma is a rare neoplasm of mesenchymal origin derived from perivascular epithelioid cells. Due to rarity, hepatic angiomyolipoma (HAML) has been often misdiagnosed as hepatocellular carcinoma (HCC) or other hypervascular liver tumors based on imaging studies. This study investigated the clinicopathological correlation and post-resection outcomes of HAML. Read More

Gut 2021 May 25. Epub 2021 May 25.

Department of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York, USA

Thorac Cancer 2021 May 19. Epub 2021 May 19.

Department of Nuclear Medicine, Cancer Institute Hospital, Koto, Tokyo, Japan.

We describe a rare case of a 64-year-old man with lung adenocarcinoma with lymph node and bone metastases who developed pseudocirrhosis. Initial examination revealed a hepatic disorder of unknown cause with narrowing of the portal vein and a low-density area surrounding the portal veins in computed tomography (CT) imaging. Diffuse liver metastasis was diagnosed after percutaneous liver biopsy. Read More

J Belg Soc Radiol 2021 May 7;105(1):25. Epub 2021 May 7.

Tan Tock Seng Hospital, SG.

This article demonstrates the technique of using a coaxial guiding needle to perform combined percutaneous biopsy and microwave ablation via a single tract. From May 2019 to July 2020, 14 patients underwent combined biopsy and microwave ablation by using a coaxial guiding cannula. Tumors were in the kidney of six patients (43%), the liver of six patients (43%), and the lung in two patients (14%). Read More

BMJ Case Rep 2021 May 12;14(5). Epub 2021 May 12.

Department of Neuroscience, University of Padova, Padova, Veneto, Italy.

Orbital metastases represent a rare condition and only 33 cases of metastases from hepatocellular carcinoma (HCC), usually revealed by slowly progressive exophthalmos, have been described in the literature. A 62-year-old man affected by HCC reported a sudden left exophthalmos and amaurosis. A cranial CT scan revealed pathological tissue occupying the superior portion of the orbit. Read More

Gan To Kagaku Ryoho 2021 Apr;48(4):531-535

Dept. of Gastroenterology, National Hospital Organization Takasaki General Medical Center.

A 72‒year‒old man with hepatocellular carcinoma(HCC)was treated with transarterial chemoembolization(TACE)and radiofrequency ablation(RFA). Six months after RFA, gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid(Gd‒ EOB‒DTPA)‒enhanced magnetic resonance imaging(MRI)revealed multiple metastatic recurrences in the liver. TACE was performed for the recurrent HCC. Read More

Pediatr Radiol 2021 May 11. Epub 2021 May 11.

APHM, Equipe d'Accueil 3279 - IFR 125, Service d'Imagerie Pédiatrique et Prénatale, Hôpital Timone Enfants, Aix Marseille Univ, Marseille, France.

We aim to present a practical approach to imaging in suspected biliary atresia, an inflammatory cholangiopathy of infancy resulting in progressive fibrosis and obliteration of extrahepatic and intrahepatic bile ducts. Left untreated or with failure of the Kasai procedure, biliary atresia progresses to biliary cirrhosis, end-stage liver failure and death within the first years of life. Differentiating biliary atresia from other nonsurgical causes of neonatal cholestasis is difficult as there is no single method for diagnosing biliary atresia and clinical, laboratory and imaging features of this disease overlap with those of other causes of neonatal cholestasis. Read More

Anticancer Res 2021 May;41(5):2727-2732

Department of Surgery, Yamaga City Medical Center, Kumamoto, Japan.

Background: Hepatic inflammatory pseudotumor (HIPT) is an uncommon benign tumor-like mass that mimics malignant tumors.

Case Report: A 73-year-old man was admitted with severe epigastric pain and high fever. He had received choledocojejunostomy. Read More

Curr Med Imaging 2021 May 4. Epub 2021 May 4.

NECMETTİN ERBAKAN ÜNİVERSİTESİ MERAM TIP FAKÜLTESİ, Turkey.

Pseudolymphoma of the liver (reactive lymphoid hyperplasia) (RLH) is a rare condition. It is usually asymptomatic and detected incidentally on radiological imaging. Imaging features are similar to hepatic adenoma, hepatocellular carcinoma, cholangiocarcinoma, and malignant lymphoma and are not specific for pseudolymphoma of the liver. Read More

Cardiovasc Intervent Radiol 2021 May 4. Epub 2021 May 4.

Division of Image Guided Minimally Invasive Surgery, Juan D. Perón 4190 (C1181ACH), Ciudad autónoma de Buenos Aires, Argentina.

Purpose: The aim of this study was to determine the effect of hyperbilirubinemia in the sensitivity of percutaneous transluminal forceps biopsy (PTFB) in patients with suspected malignant biliary stricture.

Materials And Methods: Ninety-three patients with suspicion of malignant biliary stricture underwent percutaneous transhepatic cholangiography followed by PTFB. Sensitivity, specificity and predictive values were analysed based on the presence or absence of hyperbilirubinemia, defined as total bilirubin equal to, or higher than 5 mg/dL. Read More

J Cytol 2021 Jan-Mar;38(1):21-30. Epub 2021 Feb 17.

Department of Gastroenterology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.

Context: Radiology and pathology are pivotal tools in the investigational artillery for management of wide spectrum of hepatic lesions and early detection is of a paramount importance.

Aims: The study aimed at analyzing the efficacy, comparative yield and validity of image-guided aspiration cytology (FNA)/core biopsy (CB) in focal hepatic lesions.

Settings And Design: A retrospective hospital-based study was conducted in departments of Pathology and Radiology and Imaging of a tertiary care center. Read More

Gastroenterol Nurs 2021 May-Jun 01;44(3):172-176

Deborah Hockett, BSN, RN, is Nurse Clinician III, Posner Institute for Digestive Health and Liver Diseases, Mercy Medical Center, Baltimore, Maryland.

The aim of this research study was to evaluate the effectiveness of lidocaine versus lidocaine with sodium bicarbonate in reducing anxiety and pain, using visual analog scales, in subjects receiving local anesthetic during liver biopsies. The project included 199 subjects presenting for percutaneous liver biopsy using local anesthesia. Subjects were randomized into 2 groups: the control group, which received lidocaine alone, and the experimental group, which received lidocaine buffered with sodium bicarbonate. Read More

J Small Anim Pract 2021 Apr 26. Epub 2021 Apr 26.

Department of Biomedical Sciences and Pathobiology, Virginia-Maryland College of Veterinary Medicine, Blacksburg, VA, 24061, USA.

Objectives: To assess platelet function, buccal mucosal bleeding time and plasma von Willebrand factor concentration in dogs with chronic inflammatory and/or fibrotic liver disease and to compare results with those obtained in healthy dogs.

Materials And Methods: Preliminary study including 18 dogs with chronic inflammatory and/or fibrotic liver disease undergoing liver biopsy and 18 healthy age-matched control dogs. Platelet function was assessed by measuring closure time with the PFA-100® analyser using adenosine diphosphate (ADP) as an agonist. Read More

Eur J Gastroenterol Hepatol 2021 Jul;33(7):1015-1022

Clinical Pathology Department, Faculty of Medicine, Port Said University, port said, Egypt.

Background And Aim Of The Work: Hepatocellular cancer (HCC) is one of the common liver cancers and considered to be the sixth most commonly occurring cancer in the world and the second leading cause of death among cancer patients. More recent studies on HCC showed that the elevated serum endocan level was a predictive factor of recurrence after radiofrequency ablation. The aim of this study is to evaluate the serum endocan level as a prognostic biomarker for recurrence of HCC after percutaneous radiofrequency ablation. Read More

Int J Surg Case Rep 2021 May 7;82:105852. Epub 2021 Apr 7.

Donald Gordon Medical Centre, University of the Witwatersrand, South Africa. Electronic address:

Introduction And Importance: Variceal bleeding due to intrahepatic arterioportal fistula is an unusual complication of percutaneous liver biopsy. As majority of variceal bleeding are cirrhotic in origin, the rare occurrence of an acquired intrahepatic arterioportal fistula presents a therapeutic dilemma.

Case Presentation: We report the case of a 57-year-old female with refractory variceal bleeding that occurred six years after a percutaneous liver biopsy. Read More

Cureus 2021 Mar 11;13(3):e13834. Epub 2021 Mar 11.

Digestive Diseases and Nutrition, University of Oklahoma Health Sciences Center, Oklahoma City, USA.

Benign recurrent intrahepatic cholestasis (BRIC) is a very rare autosomal recessive genetic disorder which presents with recurrent jaundice. We report the case of a young male with a history of methamphetamine use who presented with recurrent episodes of right upper quadrant abdominal pain, vomiting, dark urine, and pale stools. These symptoms always resolved within four weeks of presentation. Read More

BMC Cancer 2021 Apr 7;21(1):366. Epub 2021 Apr 7.

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Zhengzhou City, 450000, Henan Province, China.

Background: Given their widespread availability and relatively low cost, percutaneous thermal ablation is commonly performed under the guidance of computed tomography (CT) or ultrasound (US). However, such imaging modalities may be restricted due to insufficient image contrast and limited tumor visibility, which results in imperfect intraoperative treatment or an increased risk of damage to critical anatomical structures. Currently, magnetic resonance (MR) guidance has been proven to be a possible solution to overcome the above shortcomings, as it provides more reliable visualization of the target tumor and allows for multiplanar capabilities, making it the modality of choice. Read More

Rev Gastroenterol Mex (Engl Ed) 2021 Mar 30. Epub 2021 Mar 30.

Servicio de Gastroenterología y Nutrición Pediátrica, UMAE Hospital de Pediatría, Centro Médico Nacional de Occidente, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco, México.

Introduction And Aims: Percutaneous liver biopsy with histopathologic analysis is a valuable tool for the diagnosis, prognosis, and treatment evaluation of liver diseases. Its ultrasound-guided performance is useful, making the procedure safer and reducing the risk for complications and hospital stay. Our aim was to describe the indications, histopathologic study, and complications associated with the performance of ultrasound-guided percutaneous liver biopsy in pediatric patients. Read More

Clin Nucl Med 2021 Mar 16. Epub 2021 Mar 16.

From the Department of Nuclear Medicine and Specialised PET Services, The Royal Brisbane and Women's Hospital; and School of Medicine, University of Queensland, Brisbane, Australia.

Abstract: A 69-year-old woman presented with symptomatic hypercalcemia and deranged liver function. 18F-FDG PET/CT showed intense confluent avidity throughout the hepatic parenchyma, which was an isolated abnormality. Subsequent MRI demonstrated a diffuse infiltrative hepatic abnormality, with percutaneous liver biopsy findings consistent with hepatic sarcoidosis. Read More

J Ultrasound Med 2021 Mar 29. Epub 2021 Mar 29.

Mallinckrodt Institute of Radiology, Washington University, St Louis, Missouri, USA.

The purpose of this study was to describe the technique and outcomes of percutaneous thrombin injection into the superficial aspect of actively bleeding liver and kidney biopsy tracks identified with color Doppler ultrasound with the aim of hemorrhage termination. After percutaneous thrombin injection, 15/16 (94%) patients did not require further intervention. Ultrasound-guided thrombin injection into the superficial site of active bleeding is an effective technique for terminating bleeding in the immediate post-procedure period following kidney and liver biopsies and should be considered if active bleeding persists on color Doppler after ≥30 minutes of compression and observation. Read More

Gut 2021 Mar 25. Epub 2021 Mar 25.

Digestive Health Insitute, Orlando Health, Orlando, Florida, USA.

J Clin Exp Hepatol 2021 Mar-Apr;11(2):254-259. Epub 2020 Jul 19.

Department of Gastrointestinal Surgery and Liver Transplantation, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Percutaneous liver biopsy is a relatively safe procedure with low complication rates. Infections following liver biopsy are uncommon and can lead to a poor outcome. There are limited data on liver biopsy-related infections among liver transplant (LT) recipients. Read More

BMC Surg 2021 Mar 21;21(1):153. Epub 2021 Mar 21.

Department of Transplantation and Surgery, Semmelweis University, VIII. Baross u.23, Budapest, 1082, Hungary.

Background: Situs inversus totalis is a rare anatomical variation of both the thoracic and the abdominal organs. Common bile duct strictures can be caused by malignant and benign diseases as well. 7-18% of the latter ones are 'malignant masquerade' cases, as pre-operative differentiation is difficult. Read More