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Eur J Gastroenterol Hepatol 2020 Jul 8. Epub 2020 Jul 8.

School of Medicine, China Medical University, Taichung, Taiwan.

Objectives: The impact of viral eradication on hepatic angiogenesis is unknown. This study aimed to analyze the correlations of liver angiogenesis with liver fibrosis progression or regression in chronic hepatitis C (CHC) after viral eradication.

Methods: From 2003 to 2020, a cohort of 130 eligible participants underwent paired percutaneous liver biopsies (median = 48 months apart; range = 46-62) at the treatment baseline and after sustained virological response to CHC treatment at the tertiary referral center. Read More

Eur Radiol 2020 Jul 3. Epub 2020 Jul 3.

Internal Medicine Unit, Clinical and Biological Sciences Department, University of Turin, San Luigi Gonzaga University Hospital, Regione Gonzole 10, 10043 Orbassano, Turin, Italy.

Objectives: To evaluate the impact of image-guided ablation of liver and lung metastases from adrenocortical carcinoma (ACC).

Methods: Patients with oligometastatic ACC (liver and lung metastases) who underwent image-guided ablation were retrospectively included in the study. Complete ablation (CA) at the first contrast-enhanced CT control, local tumor progression (LTP), local tumor progression-free survival (LTPFS), liver disease-free survival (LDFS), and overall survival (OS) were evaluated. Read More

Ter Arkh 2020 May 19;92(4):17-22. Epub 2020 May 19.

Рeoples' Friendship University of Russia.

Detection of liver fibrosis and steatosis at early stages is a difficult task for clinical practice, due to the lack of early signs in routine radiation diagnostics.

Aim: To evaluate the efficacy of ultrasound shear elastography and ultrasound steatometry of the liver with the use of domestic ultrasonic diagnostic system Angiodin-Sono/N-Ultra.

Materials And Methods: 264 people held ultrasound elastography and ultrasound steatometry. Read More

J Pediatr Surg 2020 Jun 3. Epub 2020 Jun 3.

Division of Pediatric Surgery, Department of Surgery, Yale University, New Haven, CT. Electronic address:

Pediatr Radiol 2020 Jun 25. Epub 2020 Jun 25.

Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Background: Ultrasound shear wave elastography (SWE) measures liver stiffness noninvasively, but few studies have defined cutoff values for detecting liver fibrosis in pediatric patients using 2-D ultrasound SWE.

Objective: To evaluate the diagnostic performance of 2-D ultrasound SWE and define cutoff values for liver fibrosis in pediatric patients, using Canon (Toshiba) Aplio ultrasound systems.

Materials And Methods: This was an institutional review board-approved retrospective study of patients (≤18 years old) who had undergone both liver 2-D ultrasound SWE and percutaneous liver biopsy within 6 months. Read More

Pediatr Surg Int 2020 Aug 25;36(8):909-915. Epub 2020 Jun 25.

Department of Pediatric Surgery, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, 9 Jinsui Road, Tianhe District, Guangzhou, 510623, China.

Background/purpose: Hepatoblastoma diagnoses require liver biopsies. We aimed to investigate factors affecting the success of liver biopsy for hepatoblastoma diagnoses.

Methods: Data from patients with hepatoblastoma, including their demographic and clinical data, biopsy procedure information, pathologic diagnoses and subclassification, and surgical complications, were retrospectively reviewed. Read More

Diagn Interv Radiol 2020 Jun 19. Epub 2020 Jun 19.

Department of Diagnostic and Interventional Radiology, University-Hospital of Würzburg, Würzburg, Germany.

Purpose: We aimed to investigate the feasibility, accuracy and safety of percutaneous endobiliary cholangio-forceps biopsy of biliary strictures in our institution.

Methods: A total of 13 percutaneous transhepatic endobiliary biopsies (7 men and 6 women, mean age 66.85±16. Read More

Dig Dis Sci 2020 Jun 17. Epub 2020 Jun 17.

Division of Gastroenterology and Hepatology, H. H. Chao Comprehensive Digestive Disease Center, University of California, Irvine Medical Center, Orange, CA, 92868, USA.

Background: EUS-guided liver biopsy (EUS-LB) has been shown to be a safe and effective alternative to percutaneous liver biopsy. The optimal needle device and technique for EUS-LB is still evolving. The aim of this study was to compare the efficacy of two second-generation 19G fine-needle biopsy (FNB) (Franseen- and Fork-tip) devices for EUS-LB. Read More

J Gastrointestin Liver Dis 2020 Jun 3;29(2):181-190. Epub 2020 Jun 3.

Department of Gastroenterology and Hepatology, Victor Babeș University of Medicine and Pharmacy, Timișoara, Romania.

Aims: Our aim was to assess the diagnostic performance of transient elastography (TE) and Virtual Touch Quantification (VTQ), a point Shear Wave Elastography (pSWE) technique, using Acoustic Radiation Force Impulse (ARFI) technology, for liver fibrosis assessment, as compared to percutaneous liver biopsy (LB), in patients with chronic hepatitis B or C.

Methods: We analyzed 157 patients (80 with chronic hepatitis B and 77 with chronic hepatitis C) with reliable liver stiffness (LS) measurements, in whom we compared TE and VTQ to the LB performed during the same session (evaluated according to the Metavir scoring system: F0-F4). LS was assessed by TE (FibroScan, EchoSens, Paris, France) and VTQ using the Siemens Acuson S2000TM ultrasound system (Siemens AG, Erlangen, Germany). Read More

Diagn Pathol 2020 Jun 8;15(1):72. Epub 2020 Jun 8.

Department of Pathology, Xiangya Hospital, Central South University, 87 Xiangya Road, Kaifu District, Changsha City, 410008, Hunan Province, China.

Background: Intravascular large B-cell lymphoma (IVLBCL) is an extremely rare subtype of diffuse large B-cell lymphoma that most commonly involves the central nervous system, skin, and bone marrow. To our knowledge, Epstein-Barr virus (EBV)-positive IVLBCL in the liver has never been reported in the literature.

Case Presentation: We report a case of a 65-year-old Chinese man with complaint of fever for 18 days. Read More

Clin J Gastroenterol 2020 Jun 7. Epub 2020 Jun 7.

Department of Gastrointestinal Surgery, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo, 105-0001, Japan.

A 70-year-old man who had undergone total gastrectomy 15 years ago for mucinous gastric carcinoma on the lesser curvature of the cardia, visited our hospital complaining of cough. Chest X-ray showed a right hilar shadow and an infiltrative shadow in the left middle lung field, which was not seen in the previous year. Whole-body positron emission tomography-computed tomography (CT) revealed abnormal uptake in the irregular consolidation of the left lung, enlarged right hilar lymph nodes, and a mass lesion on the right adrenal gland. Read More

Surg Case Rep 2020 Jun 3;6(1):125. Epub 2020 Jun 3.

Department of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, 1163 Tatemachi, Hachiojishi, Tokyo, 193-0998, Japan.

Background: Granulosa cell tumor (GCT) is a type of ovarian sex cord-stromal tumor with low-grade malignancy, which can recur long after primary resection. All reports on GCTs in the liver describe cases of metastases, while there are no previous reports of primary GCTs originating from the liver. We report a case of GCT, with recurrence of liver metastasis long after ovariectomy, which was subsequently resected by a right trisectionectomy. Read More

Int J Surg Case Rep 2020 29;71:319-322. Epub 2020 May 29.

Department of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, 105-8461, Japan. Electronic address:

Introduction: The prognosis of atypical pulmonary carcinoid with liver metastases is extremely poor, and patients with multiple liver metastases are often treated using non-surgical therapies. We report a case with multiple liver metastases from atypical pulmonary carcinoid that was successfully treated using two-stage hepatectomy combined with embolization of portal vein branches.

Presentation Of Case: A 48-year-old man was referred to our department after multiple liver tumors were detected in both liver lobes on computed tomography. Read More

Respir Med Case Rep 2020 29;30:101072. Epub 2020 Apr 29.

Department of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang City, Guizhou Province, China.

Background: Acute eosinophilic pneumonia (AEP) is an acute febrile disease with good prognosis. It is often manifested as cough, dyspnea and fever, and sometimes may also as myalgia. However, there are no reports of AEP with sepsis-like symptoms of arthralgia, joint stiffness, lymph node enlargement, transient rashes and abnormal liver function in the literature. Read More

Gut 2020 Aug 28;69(8):1382-1403. Epub 2020 May 28.

Department of Gastroenterology, Royal Alexandra Hospital, Glasgow, UK.

Liver biopsy is required when clinically important information about the diagnosis, prognosis or management of a patient cannot be obtained by safer means, or for research purposes. There are several approaches to liver biopsy but predominantly percutaneous or transvenous approaches are used. A wide choice of needles is available and the approach and type of needle used will depend on the clinical state of the patient and local expertise but, for non-lesional biopsies, a 16-gauge needle is recommended. Read More

Transplant Proc 2020 May 23. Epub 2020 May 23.

Division of Gastroenterological, Hepato-Biliary-Pancreatic, Transplantation and Pediatric Surgery, Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan.

Background And Objective: Liver transplantation (LT) is the gold-standard treatment for end-stage liver disease; however, late-onset complications such as fatty liver can occur in the absence of metabolic comorbidities. We report a unique case of post-transplant hepatic steatosis developing in only a part of the liver graft.

Case Report: A 1-year-old boy underwent ABO-incompatible living donor liver transplantation (LDLT) with a left lateral liver graft donated from his mother for biliary atresia. Read More

ANZ J Surg 2020 May 26. Epub 2020 May 26.

Microbiology and Infectious Diseases, Flinders Medical Centre, Adelaide, South Australia, Australia.

Background: There have been declining mortality rates associated with pyogenic liver abscess (PLA) in recent decades due to improvements in percutaneous drainage techniques, access to imaging and improvements in supportive care. The aim of this study was to analyse the aetiology, management and outcome of PLA at a tertiary hospital in Adelaide.

Methods: Data was collected retrospectively from 80 patients who were admitted with a PLA between 2011 and 2018. Read More

Clin Mol Hepatol 2020 Jul 25;26(3):318-327. Epub 2020 May 25.

Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, Korea.

Background/aims: Liver biopsy (LB) remains the gold standard for the evaluation of liver disease. However, over the past two decades, many noninvasive tests have been developed and utilized in clinical practice as alternatives to LB. The aim of this study was to evaluate the clinical use and safety of LB in the era of noninvasive assessment of liver fibrosis. Read More

Eur J Gastroenterol Hepatol 2020 May 15. Epub 2020 May 15.

Second Department of Neurology, Institute of Psychiatry and Neurology, Warsaw, Poland.

Objectives: Staging of fibrosis in chronic liver disease is important for prognosis and treatment planning. Liver biopsy is the gold standard in fibrosis assessment; however, new methods for fibrosis and stiffness measurement exist which have not been evaluated in patients with Wilson's disease. To evaluate the accuracy of collagen proportionate area (CPA), transient elastography and shear wave elastography (SWE) in the assessment of liver fibrosis in adult patients with Wilson's disease. Read More

Chirurg 2020 May 19. Epub 2020 May 19.

Klinik für Allgemeine, Viszeral- und Transplantationschirurgie, Universitätsklinikum Tübingen, Tübingen, Deutschland.

Background: The value and safety of percutaneous liver biopsy (PLB) in brain-dead donors before organ removal and its impact on organ allocation and costs of liver transplantation (LT) in the Eurotransplant (ET) region is still a matter of ongoing debate.

Material And Methods: A PLB was performed in 36 brain-dead organ donors. The complication rate, ultrasonography findings, macroscopic evaluation and histological results of PLB and donor characteristics were analyzed. Read More

J Clin Exp Hepatol 2020 May-Jun;10(3):194-200. Epub 2019 Oct 31.

Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.

Background: To evaluate the safety and efficacy of ultrasound-guided (US-guided) omental biopsy in patients with liver cirrhosis and compare these with the noncirrhotic patients.

Methods: We retrospectively studied the US-guided omental biopsies (73 males, 14 females with mean age 52.71 ± 15. Read More

Urol Case Rep 2020 Sep 30;32:101228. Epub 2020 Apr 30.

Department of Urology, Hyogo Prefectural Nishinomiya Hospital, Japan.

Angiosarcoma arising in the retroperitoneal space is rare. We report a case of perirenal angiosarcoma presenting preoperative diagnostic difficulties. A 49-year-old man was referred to our department with left kidney mass. Read More

Brain Tumor Res Treat 2020 Apr;8(1):53-56

Department of Neurosurgery, Daegu Fatima Hospital, Daegu, Korea.

A 69-year-old male presented with a week of worsening headache, mild dizziness and left side weakness, and the radiological work-up of his brain displayed an enhancing mass on the right frontal lobe. The tumor was totally resected. The patient was initially diagnosed with glioblastoma multiforme. Read More

BMC Surg 2020 Apr 21;20(1):81. Epub 2020 Apr 21.

Division of Cancer Medicine, Department of Gastroenterological Surgery, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8641, Japan.

Background: Rhabdomyosarcoma (RMS), a malignant neoplasm that normally differentiates to form striated muscle, is the most common type of childhood soft tissue sarcoma. However, it infrequently occurs in adults and is uncommon in the liver. We herein report a case of RMS of the liver in an adult. Read More

Nat Rev Dis Primers 2020 04 9;6(1):24. Epub 2020 Apr 9.

Nuffield Department of Clinical Neurosciences, University of Oxford, West Wing, John Radcliffe Hospital, Oxford, UK.

Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. UMs are usually initiated by a mutation in GNAQ or GNA11, unlike cutaneous melanomas, which usually harbour a BRAF or NRAS mutation. The annual incidence in Europe and the USA is ~6 per million population per year. Read More

World J Clin Cases 2020 Mar;8(6):1116-1128

Department of Gastroenterology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.

Background: Hepatoid carcinoma (HC) is an extremely rare neoplasm that is morphologically similar to hepatocellular carcinoma. HC has been described in various organs; however, HC of the pancreas is extremely rare. To our knowledge, only 38 cases have been reported. Read More

Transplant Proc 2020 Jun 31;52(5):1453-1454. Epub 2020 Mar 31.

General and Digestive Surgery Department, Puerta de Hierro-Majadahonda University Hospital, Madrid, Spain.

Background: Hepatic epithelioid hemangioendothelioma (HEHE) is a rare neoplasm of vascular origin, with nonspecific presentation and unpredictable clinical course. Several therapeutic options are available according to the literature, including chemotherapy and radiotherapy, liver resection (LR), and liver transplantation (LT).

Methods: We present 2 cases of patients with HEHE treated with liver transplantation in our center, a 30-year-old man and a 42-year-old woman, diagnosed with several lesions involving both liver lobes. Read More

World J Gastrointest Endosc 2020 Mar;12(3):83-97

Department of Internal Medicine, Division of Gastroenterology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States.

Liver biopsy (LB) is an essential tool in diagnosing, evaluating and managing various diseases of the liver. As such, histopathological results are critical as they establish or aid in diagnosis, provide information on prognosis, and guide the appropriate selection of medical therapy for patients. Indications for LB include evaluation of persistent elevation of liver chemistries of unclear etiology, diagnosis of chronic liver diseases such as Wilson's disease, autoimmune hepatitis, small duct primary sclerosing cholangitis, work up of fever of unknown origin, amyloidosis and more. Read More

Int J Surg Case Rep 2020 9;68:251-256. Epub 2020 Mar 9.

Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T., Hong Kong Special Administrative Region. Electronic address:

Background And Aims: Infiltration of hepatic venous outflow in hepatic alveolar echinococcosis can lead to development of Budd-Chiari syndrome. Medical treatment of this condition is generally unsatisfactory. Radical hepatic resection is impossible for extensive parasitic involvement of liver. Read More

Transl Gastroenterol Hepatol 2020 5;5:12. Epub 2020 Jan 5.

Division of Gastroenterology, Department of Internal Medicine, University of Kentucky, Lexington, Kentucky, KY, USA.

Bile duct stones, indeterminate biliary strictures and other biliary duct pathologies represent a significant surgical and endoscopic challenge in patients with altered luminal or biliary anatomy. Traditional endoscopic retrograde cholangiopancreatography (ERCP) is not feasible and alternative approach is usually required. A novel alternative approach of addressing these challenging cases is assessed by this case series. Read More

Case Rep Surg 2020 3;2020:9605370. Epub 2020 Mar 3.

Dwight D Eisenhower Army Medical Center, Fort Gordon, Georgia.

Biloma and biliary leak after percutaneous liver biopsy (PLB) are rare. Previous cases are largely in the setting of transplant, oncology, and cirrhotic patients. Patients can be asymptomatic, peritoneal, or present with obstructive symptoms, including bilirubinemia. Read More

Medicine (Baltimore) 2020 Mar;99(11):e19545

Department of Intervention Medicine, the Second Hospital of Shandong University.

To compare the diagnostic performance of percutaneous transhepatic cholangiography and endoscopic retrograde cholangiography for the pathological assessment of suspected malignant bile duct stricture, using brush cytology and forceps biopsy.The study group comprised 79 consecutive patients who underwent pathological assessment for suspected malignant biliary stricture, 38 of whom underwent percutaneous transhepatic cholangiography (group A) and the other 41 underwent endoscopic retrograde cholangiography (group B). The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were calculated. Read More

Abdom Radiol (NY) 2020 Aug;45(8):2345-2357

Department of Radiology, Ankara Numune Education and Research Hospital, Ankara, Turkey.

Objective: To evaluate the diagnostic efficacy of intravoxel incoherent motion (IVIM) parameters in hepatitis B virus (HBV)-induced hepatic fibrosis using different calculation methods and to investigate histopathologic origins.

Materials And Methods: Liver biopsies from 37 prospectively recruited chronic hepatitis B patients were obtained. Twelve b-value (0-1000 s/mm) diffusion-weighted imaging (DWI) was performed with a 1. Read More

Dig Endosc 2020 Mar 7. Epub 2020 Mar 7.

H. H. Chao Comprehensive Digestive Center, University of California Irvine Medical Center, Orange, USA.

Intervention for liver disease has predominantly been performed through the percutaneous approach. However, as endoscopic ultrasound (EUS) applications have expanded, there have emerged various EUS-guided interventions for liver disease, a space we call "Endo-Hepatology". EUS-guided liver biopsy can be considered the "forerunner" of Endo-Hepatology and has become a clinical option for patients requiring histologic diagnosis and staging of their liver disease. Read More

Breast J 2020 Mar 5. Epub 2020 Mar 5.

Harvard Medical School, Boston, Massachusetts.

J Ultrasound 2020 Jun 5;23(2):157-167. Epub 2020 Mar 5.

Department of Gastroenterology and Hepatology, University of Missouri-School of Medicine, One Hospital Drive, Columbia, MO, 65212, USA.

Background And Aims: There is limited literature on endoscopic ultrasound-guided liver biopsy (EUS-LB), a new method of obtaining liver biopsy (LB).

Methods: We conducted a retrospective study of the efficacy and safety of EUS-LB compared to percutaneous liver biopsy (PC-LB) in patients with chronic liver disease at our center between January 2018 and August 2019.

Results: Thirty patients underwent EUS-LB and 60 patients underwent PC-LB were identified (median follow-up post-LB was 8 days; interquartile range (IQR), 3-5 days). Read More

World J Gastrointest Surg 2020 Feb;12(2):68-76

Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center Hospital, Tokyo 104-0045, Japan.

Background: A right-sided round ligament (RSRL) is a rare, congenital anomaly of the intrahepatic portal vein, with a reported frequency of 0.2%-1.2%. Read More

Radiographics 2020 Mar-Apr;40(2):562-588

From the Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 S Kingshighway Blvd, CB 8131, St Louis, MO 63110 (C.D.M., M.I., V.M.M., P.A.V., W.D.M., R.S.R.); Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Tex (D.T.F.); Department of Radiology, University of Washington Medical Center, Seattle, Wash (W.L.M.); and Department of Bioengineering, University of Washington, Seattle, Wash (M.A.A.).

US is a powerful and nearly ubiquitous tool in the practice of interventional radiology. Use of contrast-enhanced US (CEUS) has gained traction in diagnostic imaging given the recent approval by the U.S. Read More

J Dairy Sci 2020 May 26;103(5):4858-4862. Epub 2020 Feb 26.

Agriculture et Agroalimentaire Canada, Centre de recherche et développement de Sherbrooke, Sherbrooke, QC, J1M 0C8, Canada.

Glycogen, a complex polysaccharide, is the form of storage of glucose in mammals that can be released rapidly when needed. Recent studies have mainly reported hepatic glycogen concentration for early-lactating cows, when the energy demand is higher than the energy supply from dry matter intake, driving the cow to use the energy stored as hepatic glycogen. Generally, liver samples are obtained through percutaneous needle biopsies in the right lobe of the liver. Read More

Curr Opin Gastroenterol 2020 May;36(3):184-191

Department of Internal Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.

Purpose Of Review: Over the past decade, imaging modalities and serological tests have emerged as important tools in the evaluation of liver diseases, in many cases supplanting the use of liver biopsy and histological examination. Nonetheless, the accuracy and diagnostic value of these methods may not always be conclusive and the assessment of liver histology often remains the gold standard for diagnostic evaluation. The purpose of this review is to summarize the current role of liver biopsy in contemporary hepatology practice. Read More

Med Ultrason 2020 03;22(1):20-25

Octavian Fodor Regional Institute of Gastroenterology and Hepatology, Department of Radiology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Aim: Endoscopic ultrasound (EUS) has become an indispensable method for diagnosis in gastroenterology and new indications for EUS continue to emerge. However, there are limited data regarding the accuracy of EUS-guided biopsy of hepatic focal lesions. The aim of this study was to assess the diagnostic yield of EUS-guided fine needle aspiration (FNA) of focal liver lesions. Read More

Liver Int 2020 Feb;40 Suppl 1:109-115

"Equipe labellisée Ligue Contre le Cancer", Université Paris 13, Sorbonne Paris Cité, Saint-Denis, France.

The goal of curative management of hepatocellular carcinoma is to provide the best chance of remission. However, recurrence rates for both local and distant relapse are high. Patient subgroups at higher risk of these events can be identified based on histological patterns that are closely linked to specific molecular subtypes. Read More

Zhonghua Yi Xue Za Zhi 2020 Feb;100(5):387-390

Department of Interventional Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.

To evaluate the efficacy and safety of transjugular intrahepatic portosystemic shunt(TIPS) for the treatment of patients with cavernous transformation of portal vein (CTPV) with vareceal bleeding. From September 2016 to June 2018, a total of 21 patients suffered CTPV complicated with vareceal bleeding were admitted to First Affiliated Hospital of Zhengzhou University. TIPS were performed combined with percutaneous transhepatic portal vein assist. Read More

Cochrane Database Syst Rev 2020 02 4;2:CD008717. Epub 2020 Feb 4.

Jagiellonian University Medical College, Chair of Epidemiology and Preventive Medicine, Department of Hygiene and Dietetics; Systematic Reviews Unit, Kopernika 7, Krakow, Poland, 31-034.

Background: The liver is affected by two of the most common groups of malignant tumours: primary liver tumours and liver metastases from colorectal carcinoma or other extrahepatic primary cancers. Liver metastases are significantly more common than primary liver cancer, and the reported long-term survival rate after radical surgical treatment is approximately 50%. However, R0 resection (resection for cure) is not feasible in the majority of patients; therefore, other treatments have to be considered. Read More

Medicine (Baltimore) 2020 Jan;99(3):e18855

Department of Pathology, Far Eastern Memorial Hospital, New Taipei City, Taiwan.

Rationale: Prolonged cholestasis is a rare complication associated with endoscopic retrograde cholangiopancreatography (ERCP).

Patient Concerns: A 68-year-old man who presented with worsening cholestasis after ERCP for the removal of a common bile duct stone.

Diagnosis: Total bilirubin increased up to 35. Read More

Int J Surg Case Rep 2020 27;67:45-50. Epub 2020 Jan 27.

Hirota Institute for Surgical Pathology, Idaimae 3-6-5, Shimotuke City, Tochigi, Japan.

Introduction: Laparoscopic cholecystectomy for patients with acute cholecystitis and liver cirrhosis is associated with increased risk. We present an obese patient with acute cholecystitis and liver cirrhosis caused by nonalcoholic steatohepatitis (NASH), who was successfully managed with laparoscopic cholecystostomy and a low-carbohydrate diet with exercise.

Presentation Of Case: A 61-year-old woman presented with right upper quadrant abdominal pain. Read More

J Ultrasound Med 2020 Jul 30;39(7):1355-1365. Epub 2020 Jan 30.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Objectives: Percutaneous liver biopsy (LB) has been considered the reference standard in distinguishing the degree of liver disease, but there has been no definitive systematic review to assess complication rates or potential risk factors for them.

Methods: In this study, we searched the PubMed, Embase, Web of Science, and Scopus databases for studies appraising complication rates after percutaneous ultrasound (US)-guided LB published until October 11, 2018. The safety and efficacy of US-guided LB were estimated according to major and minor complications. Read More

J Vasc Interv Radiol 2020 Mar 16;31(3):482-491.e4. Epub 2020 Jan 16.

Department of Small Animal Clinical Sciences, Virginia-Maryland College of Veterinary Medicine, DSACS, Phase II, 205 Duck Pond Drive (0442), Blacksburg, VA 24061. Electronic address:

Purpose: To determine the safety and feasibility of percutaneous high-frequency irreversible electroporation (HFIRE) for primary liver cancer and evaluate the HFIRE-induced local immune response.

Materials And Methods: HFIRE therapy was delivered percutaneously in 3 canine patients with resectable hepatocellular carcinoma (HCC) in the absence of intraoperative paralytic agents or cardiac synchronization. Pre- and post-HFIRE biopsy samples were processed with histopathology and immunohistochemistry for CD3, CD4, CD8, and CD79a. Read More

Int J Clin Exp Pathol 2019 1;12(1):378-383. Epub 2019 Jan 1.

Mental Health Center, West China Hospital of Sichuan University Chengdu, Sichuan, China.

A 41-year-old man was admitted to the hepatobiliary surgery department of West China Hospital for right upper abdominal pain lasting for more than three months. The local hospital's abdominal computed tomography (CT) showed an unclear low density shadow in the right and lateral lobes of the liver and nodules on the abdominal wall. A histologic analysis of an ultrasound guided percutaneous hepatic biopsy revealed it was hepatic sarcomatoid carcinoma (HSC). Read More