60,190 results match your criteria Percutaneous Coronary Intervention


In-hospital and long-term outcomes of HIV-positive patients undergoing PCI according to kind of stent: a meta-analysis.

J Cardiovasc Med (Hagerstown) 2019 Jan 18. Epub 2019 Jan 18.

Division of Cardiology, Department of Internal Medicine, Città Della Salute e della Scienza, University of Turin, Turin, Italy.

Background: Pathogenesis of cardiovascular disease in HIV-positive patients is related to the interaction between traditional and HIV-specific factors. Limited data are available regarding the prognosis of HIV-positive patients undergoing percutaneous coronary intervention (PCI).

Methods: All observational studies evaluating the prognosis of HIV-positive patients treated with PCI were included. Read More

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http://dx.doi.org/10.2459/JCM.0000000000000767DOI Listing
January 2019

A New Dimension in the Relationship Between Procedural Volumes and Quality.

Circulation 2019 Jan;139(4):473-476

Brigham and Women's Hospital Heart and Vascular Center, and Harvard Medical School, Boston, MA (D.L.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.037383DOI Listing
January 2019

[DIRECT ADMISSION OF STEMI PATIENTS TO THE CARDIAC CARE UNIT VERSUS ADMISSION VIA THE EMERGENCY DEPARTMENT FOR PRIMARY CORONARY INTERVENTION IMPROVES SHORT AND LONG-TERM SURVIVAL].

Harefuah 2019 Jan;158(1):35-40

Heart Institute, Hillel Yaffe Medical Center, Hadera, Israel, affiliated to the Bruce Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa - Israel.

Introduction: Shortening door-to-balloon time intervals in ST-elevation myocardial infarction (STEMI) patients treated by primary percutaneous coronary intervention (PPCI) is necessary in order to limit myocardial damage. Direct admission to the cardiac care unit (CCU) facilitates this goal. We compared characteristics and short- and long-term mortality of PPCI-treated STEMI patients admitted directly to the CCU with those admitted via the emergency department (ED). Read More

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January 2019

Extravascular compared to Intravascular Femoral Closure is Associated with Less Bleeding and Similar MACE after Percutaneous Coronary Intervention.

Int J Med Sci 2019 1;16(1):43-50. Epub 2019 Jan 1.

First Department of Medicine, University Medical Centre Mannheim (UMM), Faculty of Medicine Mannheim, University of Heidelberg, European Center for AngioScience (ECAS), and DZHK (German Center for Cardiovascular Research) partner site Heidelberg/Mannheim, Mannheim, Germany.

Various types of vascular closure devices (VCDs) are frequently utilized in patients undergoing percutaneous coronary intervention (PCI) in order to prevent arterial access site bleeding, which represents one of the most relevant complications associated with adverse clinical outcomes. This study aims to compare directly two mechanistically different types of femoral closure (FC) devices in patients undergoing PCI. This single-center, prospective, observational study includes consecutively patients either treated by the extravascular StarClose SE® (Abbott, Illinois, U. Read More

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http://www.medsci.org/v16p0043.htm
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http://dx.doi.org/10.7150/ijms.29253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332477PMC
January 2019
1 Read

The role of simulation-based education in cardiology.

Authors:
Khalid Barakat

Heart 2019 Jan 19. Epub 2019 Jan 19.

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http://dx.doi.org/10.1136/heartjnl-2017-311153DOI Listing
January 2019

Acute Microvascular Impairment Post-Reperfused STEMI Is Reversible and Has Additional Clinical Predictive Value: A CMR OxAMI Study.

JACC Cardiovasc Imaging 2019 Jan 9. Epub 2019 Jan 9.

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom. Electronic address:

Objectives: This study sought to investigate the clinical utility and the predictive relevance of absolute rest myocardial blood flow (MBF) by cardiac magnetic resonance (CMR) in acute myocardial infarction.

Background: Microvascular obstruction (MVO) remains one of the worst prognostic factors in patients with reperfused ST-segment elevation myocardial infarction (STEMI). Clinical trials have focused on cardioprotective strategies to maintain microvascular functionality, but there is a need for a noninvasive test to determine their efficacy. Read More

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http://dx.doi.org/10.1016/j.jcmg.2018.10.028DOI Listing
January 2019

5 Years of Serial Intravascular Imaging Outcomes of XINSORB Sirolimus-Eluting Bioresorbable Vascular Scaffold.

JACC Cardiovasc Interv 2019 Jan 9. Epub 2019 Jan 9.

Department of Cardiology, Shanghai Institute of Cardiovascular Diseases, Zhongshan Hospital, Fudan University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.jcin.2018.11.029DOI Listing
January 2019

Study of arterial stiffness in patients with an acute coronary event and chronic obstructive pulmonary disease confirmed by spirometry.

Rev Clin Esp 2019 Jan 16. Epub 2019 Jan 16.

Departamento de Medicina Interna, Hospital Universitario Mútua Terrasa, Universidad de Barcelona, Terrasa, Barcelona, España.

Background And Objectives: Chronic obstructive pulmonary disease (COPD) worsens the prognosis for patients with an acute coronary event (ACE) treated with percutaneous coronary intervention. Objective To assess the effect of COPD on arterial stiffness in patients with an ACE.

Methods: The study included patients with an ACE treated with percutaneous coronary intervention. Read More

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http://dx.doi.org/10.1016/j.rce.2018.08.007DOI Listing
January 2019

Plasminogen activator inhibitor 1 in acute coronary syndromes.

Clin Chim Acta 2019 Jan 16. Epub 2019 Jan 16.

Department of Clinical Chemistry, Sestre milosrdnice University Hospital Centre, Vinogradska cesta 29, 10000 Zagreb, Croatia.

Plasminogen activator inhibitor 1 (PAI-1) is the main regulator of endogenous fibrinolysis, overriding the impact of other constituents of fibrinolysis. In plasma, it can be found in three forms: active, latent and inactive. There are numerous commercially available tests, analysing the activity of PAI-1 or the antigen level, with variable correlations between the two. Read More

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http://dx.doi.org/10.1016/j.cca.2019.01.013DOI Listing
January 2019

Left main and triple vessel dissection 2 months postpartum.

Catheter Cardiovasc Interv 2019 Jan 18. Epub 2019 Jan 18.

Department of Medicine, University of California Los Angeles, Los Angeles, California.

Spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome. The majority of cases reported in the literature involve a single vessel; multivessel and left main (LM) coronary artery involvement is rare. We present a case of triple vessel and LM SCAD in a postpartum patient and review the literature regarding percutaneous coronary intervention in the setting of SCAD. Read More

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http://dx.doi.org/10.1002/ccd.28046DOI Listing
January 2019

Evaluation of a Diagnostic Test of Serum Neutrophil Gelatinase-Associated Lipocalin (NGAL) and Urine KIM-1 in Contrast-Induced Nephropathy (CIN).

Med Sci Monit 2019 Jan 19;25:565-570. Epub 2019 Jan 19.

Department of Geriatrics, Qinghai Provincial People's Hospital, Xining, Qinghai, China (mainland).

BACKGROUND The aim of this study was to assess changes in serum neutrophil gelatinase-associated lipocalin (NGAL) and urine KIM-1 after percutaneous coronary intervention (PCI). MATERIAL AND METHODS A total of 240 patients receiving coronary stent implantation were selected. All patients were divided into 2 groups: a CIN group (n=25) and a non-CIN group (n=215). Read More

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http://dx.doi.org/10.12659/MSM.912569DOI Listing
January 2019

Comparison of clinical outcomes between sufficient versus insufficient diagonal branch flow in anterior acute myocardial infarction.

Heart Vessels 2019 Jan 18. Epub 2019 Jan 18.

Division of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama, 330-8503, Saitama, Japan.

In primary percutaneous coronary intervention (PCI), revascularization to the main branch is considered to be more important than that to the side branch. The purpose of the present study was to compare in-hospital clinical outcomes between sufficient and insufficient diagonal flow in patients with anterior ST-elevation acute myocardial infarction. A total of 229 left anterior descending artery (LAD)-AMI with final Thrombolysis in Myocardial Infarction (TIMI)-3 LAD flow were included, and divided into the sufficient diagonal flow group (TIMI-3 diagonal flow: n = 170) and the insufficient diagonal flow group (TIMI ≤ 2 diagonal flow: n = 59). Read More

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http://dx.doi.org/10.1007/s00380-019-01343-yDOI Listing
January 2019

Event dependence in the analysis of cardiovascular readmissions postpercutaneous coronary intervention.

J Investig Med 2019 Jan 18. Epub 2019 Jan 18.

Baylor Heart and Vascular Institute, Baylor University Medical Center at Dallas, Dallas, Texas, USA.

Recurrent hospitalizations are common in longitudinal studies; however, many forms of cumulative event analyses assume recurrent events are independent. We explore the presence of event dependence when readmissions are spaced apart by at least 30 and 60 days. We set up a comparative framework with the assumption that patients with emergency percutaneous coronary intervention (PCI) will be at higher risk for recurrent cardiovascular readmissions than those with elective procedures. Read More

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http://dx.doi.org/10.1136/jim-2018-000873DOI Listing
January 2019
1 Read

Electrocardiographic Distinction of Left Circumflexand Right Coronary Artery Occlusion in PatientsWith Inferior Acute Myocardial Infarction.

Am J Cardiol 2019 Jan 4. Epub 2019 Jan 4.

Cardiology Department, Hospital de la Santa Creu i Sant Pau, CIBERCV, Departament de Medicina de la Universitat Autònoma de Barcelona, Barcelona, Spain.

Previously reported electrocardiographic (ECG) criteria to distinguish left circumflex (LCCA) and right coronary artery (RCA) occlusion in patients with acute inferior ST-segment elevation myocardial infarction (STEMI) afford a modest diagnostic accuracy. We aimed to develop a new algorithm overcoming limitations of previous studies. Clinical, ECG, and coronary angiographic data were analyzed in 230 nonselected patients with acute inferior STEMI who underwent primary percutaneous coronary intervention. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.12.026DOI Listing
January 2019

Level and variation on quality of care in China: a cross-sectional study for the acute myocardial infarction patients in tertiary hospitals in Beijing.

BMC Health Serv Res 2019 Jan 18;19(1):43. Epub 2019 Jan 18.

Harvard Global Health Institute, Boston, USA.

Background: Quality of care (QoC) attracts global concerns when unsafe and misuse of healthcare wastes resources and endangers people's health, especially in low- and middle-income countries. However, little is known about quality of care delivered in China. This study was intended to gauge the quality of care for acute myocardial infarction (AMI) patients in Beijing and identify the quality gaps across tertiary hospitals. Read More

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http://dx.doi.org/10.1186/s12913-019-3872-0DOI Listing
January 2019

Clinical results of bioresorbable drug-eluting scaffolds in short and long coronary artery lesions using the PSP technique.

BMC Cardiovasc Disord 2019 Jan 18;19(1):22. Epub 2019 Jan 18.

Department of Internal Medicine II, University Hospital of Ulm, Ulm, Germany.

Background: Data on bioresorbable vascular scaffolds (BVS) for the treatment of long lesions are limited. We studied the use of BVS-Absorb in routine clinical practice and compared the outcome of long lesions with short lesions. Implantation of drug-eluting scaffolds without PSP-technique (predilation, proper sizing and postdilation) is associated with an increased thrombotic risk. Read More

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http://dx.doi.org/10.1186/s12872-018-0994-yDOI Listing
January 2019

LncRNA-mRNA competing endogenous RNA network depicts transcriptional regulation in ischaemia reperfusion injury.

J Cell Mol Med 2019 Jan 18. Epub 2019 Jan 18.

Zhongshan Hospital, Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China.

The study aimed to investigate time-course transcriptomes in myocardial ischaemia reperfusion injury (IRI) via RNA-Seq. Transcriptomes of 10 samples derived from patients with acute ST-segment elevation myocardial infarction (ASTEMI) who were assigned to percutaneous coronary intervention (PCI), were sequenced at the time of 0 (before PCI), 2, 12, 24 and 72 hours after PCI, respectively. Using the genefilter package in r, wgcna and stem, different expression lncRNA (DEL) and mRNA (DEM) were analysed. Read More

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http://doi.wiley.com/10.1111/jcmm.14163
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http://dx.doi.org/10.1111/jcmm.14163DOI Listing
January 2019
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Predictive factors for new-onset atrial fibrillation in acute coronary syndrome patients undergoing percutaneous coronary intervention.

Panminerva Med 2019 Jan 17. Epub 2019 Jan 17.

Department of Cardiovascular Medicine, Taizhou People's Hospital, Taizhou, China.

Background: To study the predictive factors for new-onset atrial fibrillation (AF) in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI).

Methods: A total of 934 ACS patients admitted into the Department of Cardiology from February 2015 to February 2017 were collected. All patients were treated with PCI after admission and followed up for 1 year. Read More

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https://www.minervamedica.it/index2.php?show=R41Y9999N00A190
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http://dx.doi.org/10.23736/S0031-0808.18.03556-5DOI Listing
January 2019
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Use of prasugrel and clinical outcomes in African-American patients treated with percutaneous coronary intervention for acute coronary syndromes.

Catheter Cardiovasc Interv 2019 Jan 17. Epub 2019 Jan 17.

Icahn School of Medicine at Mount Sinai, New York, New York.

Objective: To investigate the use of prasugrel after percutaneous coronary intervention (PCI) in African American (AA) patients presenting with acute coronary syndrome (ACS).

Background: AA patients are at higher risk for adverse cardiovascular outcomes after PCI and may derive greater benefit from the use of potent antiplatelet therapy.

Methods: Using the multicenter PROMETHEUS observational registry of ACS patients treated with PCI, we grouped patients by self-reported AA or other races. Read More

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http://dx.doi.org/10.1002/ccd.28033DOI Listing
January 2019

The clinical effects of CYP2C19 *2 allele frequency on Palestinian patients receiving clopidogrel after percutaneous coronary intervention.

Int J Clin Pharm 2019 Jan 17. Epub 2019 Jan 17.

Faculty of Medicine, the Islamic University of Gaza, Gaza, Palestine.

BackgroundCYP2C19 loss-of-function polymorphic alleles (*2 and *3) have been documented to impair clopidogrel metabolism, and represent a risk factor for major adverse cardiac events. CYP2C19 polymorphism exhibits marked ethnic heterogeneity. Objective To determine the prevalence of CYP2C19 *2 and *3 alleles in a cohort of Palestinian patients managed with percutaneous coronary intervention and dual antiplatelet therapy, and to determine their role in causing major adverse cardiac events. Read More

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http://link.springer.com/10.1007/s11096-018-00782-3
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http://dx.doi.org/10.1007/s11096-018-00782-3DOI Listing
January 2019
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The association between recent hospitalized COPD exacerbations and adverse outcomes after percutaneous coronary intervention: a nationwide cohort study.

Int J Chron Obstruct Pulmon Dis 2019 3;14:169-179. Epub 2019 Jan 3.

Department of Surgery, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan,

Purpose: COPD is associated with coronary artery disease, and exacerbations are major events in COPD. However, the impact of recent hospitalized exacerbations on outcomes of percutaneous coronary intervention (PCI) remains underdetermined.

Patients And Methods: Using the National Health Insurance Research Database of Taiwan, we identified 215,275 adult patients who underwent first-time PCI between 2000 and 2012. Read More

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https://www.dovepress.com/the-association-between-recent-hos
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http://dx.doi.org/10.2147/COPD.S187345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322514PMC
January 2019
1 Read

Factors associated with delay in transfer of patients with ST-segment elevation myocardial infarction from first medical contact to catheterization laboratory: Lessons from CRAC, a French prospective multicentre registry.

Arch Cardiovasc Dis 2019 Jan 14. Epub 2019 Jan 14.

Unité régionale d'épidémiologie hospitalière (UREH), 37044 Tours, France.

Background: It is critical to minimize the time between the first medical contact and primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction.

Aims: To identify factors associated with a delay of>120min between first medical contact and primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction.

Methods: Data were analysed from a regional French registry of patients undergoing coronary angioplasty for ST-segment elevation myocardial infarction<24h after symptom onset. Read More

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http://dx.doi.org/10.1016/j.acvd.2018.04.008DOI Listing
January 2019

Meta-Analysis of the Role of Cangrelor for Patients Undergoing Percutaneous Coronary Intervention.

Am J Cardiol 2019 Jan 5. Epub 2019 Jan 5.

Department of Internal Medicine, University of Nevada Reno School of Medicine, Reno, Nevada. Electronic address:

Inhibition of the P2Y12 receptor by an oral P2Y12 inhibitor with loading doses along with Cyclooxygenase-1 inhibition by aspirin is considered a first-line treatment strategy in patients with the acute coronary syndrome and patients undergoing percutaneous coronary intervention (PCI). Limitations associated with oral P2Y12 receptor inhibitors include a requirement for in vivo conversion (thienopyridines), delayed onset of action, suboptimal inhibition, irreversible inhibition (thienopyridines), and delayed offset. In the acute setting, therapy with potent platelet inhibitors that have a fast onset and offset is desirable to attenuate thrombotic complications. Read More

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http://dx.doi.org/10.1016/j.amjcard.2018.12.039DOI Listing
January 2019

Value of the SYNTAX Score in ST-Elevation Myocardial Infarction Patients With a Concomitant Chronic Total Coronary Occlusion(from the EXPLORE Trial).

Am J Cardiol 2019 Jan 4. Epub 2019 Jan 4.

Academic Medical Center, Amsterdam, the Netherlands.

`To analyze the impact of additional coronary artery disease, quantified by the SYNTAX (SYNergy between PCI with TAXus and cardiac surgery) score, on left ventricular ejection fraction (LVEF) and long-term outcomes in a cohort of ST-elevated myocardial infarction (STEMI) patients with a concomitant chronic total coronary occlusion (CTO). A total of 302 STEMI patients were randomized to percutaneous coronary intervention of a CTO (CTO PCI) (n = 148) or conservative CTO treatment (n = 154). SYNTAX scores were calculated by an independent corelab (Cardialysis BV, Rotterdam) at two time-points: (1) at baseline, and (2) after primary PCI in the conservative CTO arm and after CTO PCI in the invasive arm (named 'discharge SYNTAX score'). Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029149193003
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http://dx.doi.org/10.1016/j.amjcard.2018.12.028DOI Listing
January 2019
2 Reads

Effects of mitochondrial ATP-sensitive potassium channel activation (nicorandil) in patients with angina pectoris undergoing elective percutaneous coronary interventions: A meta-analysis of randomized controlled trials.

Medicine (Baltimore) 2019 Jan;98(3):e14165

The Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Aims: Nicorandil, which is a mitochondrial ATP-sensitive potassium channel opener, is believed to improve perioperative myocardial injury (PMI) in patients undergoing percutaneous coronary intervention (PCI), but recent studies have shown that nicorandil treatment did not improve functional and clinical outcomes in patients with angina pectoris who underwent elective PCI. We performed a meta-analysis to investigate the protective effect of nicorandil on perioperative injury in patients with angina pectoris who underwent elective PCI.

Methods: The Medline, EMBASE, and Cochrane databases were searched for randomized clinical trials examining the effects of nicorandil. Read More

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http://dx.doi.org/10.1097/MD.0000000000014165DOI Listing
January 2019

Spontaneous closure of an iatrogenic coronary artery fistula during recanalization of a chronic total occlusion lesion: A case report.

Medicine (Baltimore) 2019 Jan;98(3):e14068

Department of Cardiology, Beijing Hospital, National Center of Gerontology, Beijing, China.

Rationale: Coronary perforation leading to fistula directed to the right ventricle is a rare complication of percutaneous coronary intervention (PCI). The reported outcomes vary from a stable state to rapid deterioration.

Patient Concerns: An 86-year-old man was diagnosed with non-ST elevation myocardial infarction, and arranged to PCI procedure for the chronic total occluded right coronary artery (RCA) after coronary angiography. Read More

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http://dx.doi.org/10.1097/MD.0000000000014068DOI Listing
January 2019
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Evaluation of myocardial viability in patients with acute myocardial infarction: Layer-specific analysis of 2-dimensional speckle tracking echocardiography.

Medicine (Baltimore) 2019 Jan;98(3):e13959

Institute of Cardiovascular Disease, Xuzhou Medical University, Xuzhou 221002, Jiangsu Province.

Background: The value of layer-specific two-dimensional speckle tracking echocardiography (LS2D-STE) for evaluating viable myocardium (VM) in patients with acute myocardial infarction (AMI) was unclear, this study provides new insights into it and to make a comparison with dualisotope simultaneous acquisition single photon emission computed tomography ( DISA-SPECT).

Methods: Forty hospitalized patients with AMI and left ventricular systolic dysfunction (left ventricular ejection fraction <50%) underwent LS2D-STE and DISA-SPECT before percutaneous coronary intervention (PCI). The longitudinal, circumferential, and radial peak systolic strains and the peak systolic strain rates of 3 myocardiallayers (endocardium, mid-myocardium, and epicardium), as well as the total wall thickness, were determined by LS2D-STE. Read More

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http://dx.doi.org/10.1097/MD.0000000000013959DOI Listing
January 2019

Lateral Costal Artery: Clinical Importance of an Accessory Thoracic Artery.

Braz J Cardiovasc Surg 2018 Nov-Dec;33(6):626-630

Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey.

The lateral costal artery has sometimes been identified as the culprit for the "steal phenomenon" after coronary artery bypass grafting, besides being occasionally used for myocardial revascularization. Its branches make anastomoses with the internal thoracic artery through lateral intercostal arteries. We aim to report, on three cases, the clinical significance of a well-developed lateral costal artery after coronary artery bypass grafting. Read More

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http://www.bjcvs.org/pdfRBCCV/v33n6a16.pdf
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http://dx.doi.org/10.21470/1678-9741-2017-0252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326454PMC
December 2017
1 Read

The Importance of Intra-aortic Pulse Pressure After Anterior ST-segment Elevation Myocardial Infarction.

Braz J Cardiovasc Surg 2018 Nov-Dec;33(6):579-587

Department of Cardiology, Near East University Faculty of Medicine, Nicosia, Cyprus.

Objective: To evaluate the association of pulse pressure (PP) with mortality and major adverse cardiac events (MACE) in one-year period after anterior ST-elevation myocardial infarction (A-STEMI).

Methods: A total of 261 consecutive patients whose blood pressure was measured with the aid of a catheter before primary percutaneous coronary intervention (PPCI) between August 2016 and February 2017 were included in the study. The patients were divided into three groups according to pulse pressure (PP) (Group 1, PP<35 mmHg; Group 2, 35≤PP≤50 mmHg; Group 3, PP>50 mmHg). Read More

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http://dx.doi.org/10.21470/1678-9741-2018-0106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326447PMC

microRNA-26a-5p affects myocardial injury induced by coronary microembolization by modulating HMGA1.

J Cell Biochem 2019 Jan 16. Epub 2019 Jan 16.

Guangxi Key Laboratory of Regenerative Medicine, Guangxi Medical University, Nanning, Guangxi, China.

Coronary microembolization (CME) occurs when atherosclerotic plaque debris is detached during the treatment of acute coronary syndrome with Percutaneous Coronary Intervention (PCI). The complications of distal microvascular embolism, including local myocardial inflammation, are the main causes of myocardial damage and are a strong predictor of poor long-term prognosis and major cardiac adverse events. microRNAs (miRNAs) are involved in the pathophysiological processes of cardiovascular inflammatory diseases. Read More

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http://doi.wiley.com/10.1002/jcb.28367
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http://dx.doi.org/10.1002/jcb.28367DOI Listing
January 2019
1 Read

Serum Triglyceride Lipase Concentrations are Independent Risk Factors for Coronary Artery Disease and In-Stent Restenosis.

J Atheroscler Thromb 2019 Jan 17. Epub 2019 Jan 17.

Department of Cardiology, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University.

Aim: Endothelial lipase (EL), hepatic lipase (HL), and lipoprotein lipase (LPL) are all triglyceride lipases and are associated with coronary artery disease (CAD). However, whether they can be simultaneous independent risk factors for CAD is unknown. In the present study, we investigated whether the three lipases can be independent risk factors simultaneously for CAD and whether combining these lipases could provide greater predictive power than high-density lipoprotein cholesterol (HDL-c) for the development of CAD. Read More

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https://www.jstage.jst.go.jp/article/jat/advpub/0/advpub_468
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http://dx.doi.org/10.5551/jat.46821DOI Listing
January 2019
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Sirolimus nanoparticles: (Delivering) a new hope in stentless percutaneous coronary intervention?

Cardiovasc Revasc Med 2019 Jan 6. Epub 2019 Jan 6.

Department of Cardiology, National University Heart Centre, Singapore, Singapore.

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http://dx.doi.org/10.1016/j.carrev.2019.01.004DOI Listing
January 2019

Chronic kidney disease predicts atrial fibrillation in patients with ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention.

Acta Cardiol 2019 Jan 16:1-8. Epub 2019 Jan 16.

a University of Medicine and Pharmacy of Tîrgu Mureș , Tîrgu Mureș , Romania.

Background: Atrial fibrillation (AF) often complicates ST-segment elevation myocardial infarction (STEMI). Predictors of AF in this setting include factors related to the acute phase of STEMI and pre-existing conditions. More recently, novel AF predictors have been identified in the general population. Read More

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http://dx.doi.org/10.1080/00015385.2018.1521558DOI Listing
January 2019
1 Read

Combination Therapy with Dipyridamole and Clopidogrel for Secondary Stroke Prevention in Aspirin-Intolerant Patients After Myocardial Infarction: Results of a Nationwide Case-Control Study.

CNS Drugs 2019 Jan 16. Epub 2019 Jan 16.

Department of Critical Care Medicine, Kaohsiung Veterans General Hospital, No. 386, Dazhong 1st Rd, Zuoying District, Kaohsiung, 813, Taiwan.

Background And Purpose: Combination therapy with dipyridamole and clopidogrel in stroke prevention and long-term outcomes in aspirin-intolerant patients with acute myocardial infarction (AMI) and previous stroke are unknown. This nationwide study analyzed the impact of dipyridamole and clopidogrel on secondary stroke prevention and long-term outcomes in aspirin-intolerant stroke patients after AMI.

Methods: This was a nationwide, case-control study involving 186,112 first AMI patients, 78,607 of whom had a previous history of stroke. Read More

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http://dx.doi.org/10.1007/s40263-018-0591-8DOI Listing
January 2019

Risk factors for subsequent work disability in patients with acute myocardial infarction.

Eur J Public Health 2019 Jan 14. Epub 2019 Jan 14.

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm SE-171 77, Sweden.

Background: Scientific knowledge on risk factors for work disability in terms of long-term sickness absence (SA) and disability pension (DP) following acute myocardial infarction (AMI) is limited. The study aimed to investigate socio-demographic, work-related and medical characteristics as risk factors for long-term SA (>90 days) and DP in patients with a first AMI.

Methods: This is a population-based cohort study of 8199 individuals aged 19-60 years who had a first AMI during 2008-10 and were alive 30 days after AMI. Read More

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/eurpub/cky279DOI Listing
January 2019
1 Read

Association of State Medicaid Expansion With Quality of Care and Outcomes for Low-Income Patients Hospitalized With Acute Myocardial Infarction.

JAMA Cardiol 2019 Jan 16. Epub 2019 Jan 16.

Washington University School of Medicine in St Louis, St Louis, Missouri.

Importance: Lack of insurance is associated with worse care and outcomes among adults hospitalized for acute myocardial infarction (AMI). It is unclear whether states' decision to expand Medicaid eligibility under the Patient Protection and Affordable Care Act in 2014 were associated with improved quality of care and outcomes among low-income patients hospitalized with AMI.

Objective: To investigate whether rates of uninsurance, quality of care, and outcomes changed among patients hospitalized for AMI 3 years after states elected to expand Medicaid compared with nonexpansion states. Read More

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http://dx.doi.org/10.1001/jamacardio.2018.4577DOI Listing
January 2019

Decision to deploy coronary reperfusion is not affected by the volume of ST-segment elevation myocardial infarction patients managed by prehospital emergency medical teams.

Eur J Emerg Med 2019 Jan 14. Epub 2019 Jan 14.

SAMU 78, Versailles Hospital, Le Chesnay.

Objective: Mortality in patients with ST-segment elevation myocardial infarction (STEMI) has been associated with the volume of activity of percutaneous coronary intervention (PCI) facilities. This observational study investigated whether the coronary reperfusion-decision rate is associated with the volume of activity in a prehospital emergency setting.

Methods: Prospectively collected data for the period 2003-2013 were extracted from a regional registry of all STEMI patients handled by eight dispatch centers (SAMUs) in and around Paris [41 mobile ICU (MICUs)]. Read More

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http://dx.doi.org/10.1097/MEJ.0000000000000586DOI Listing
January 2019

Baseline Serum Uric Acid Levels Are Associated with All-Cause Mortality in Acute Coronary Syndrome Patients after Percutaneous Coronary Intervention.

Dis Markers 2018 17;2018:9731374. Epub 2018 Dec 17.

Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.

Background: Whether serum uric acid (UA) is associated with all-cause mortality in patients with acute coronary syndrome (ACS) following percutaneous coronary intervention (PCI) remains unclear.

Methods: We performed a retrospective cohort study of 2296 patients with ACS. Curve-fitting and Cox proportional-hazard regression models with a hazard ratio (HR) and 95% confidence interval (CI) were used. Read More

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http://dx.doi.org/10.1155/2018/9731374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311730PMC
December 2018

Cost-effectiveness analysis of pharmacogenomics-guided clopidogrel treatment in Spanish patients undergoing percutaneous coronary intervention.

Pharmacogenomics J 2019 Jan 16. Epub 2019 Jan 16.

The Golden Helix Foundation, London, UK.

Clopidogrel is an antiplatelet drug given to patients before and after having a percutaneous coronary intervention (PCI). Genomic variants in the CYP2C19 gene are associated with variable enzyme activities affecting drug metabolism and hence, patients with reduced or increased enzymatic function have increased risk of bleeding. We conducted a cost-effectiveness analysis to compare a pharmacogenomics versus a non-pharmacogenomics-guided clopidogrel treatment for coronary artery syndrome patients undergoing PCI in the Spanish healthcare setting. Read More

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http://www.nature.com/articles/s41397-019-0069-1
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http://dx.doi.org/10.1038/s41397-019-0069-1DOI Listing
January 2019
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Thrombotic/Thrombolytic Balance as a Cardiac Treatment Determinant in Patients With Diabetes Mellitus and Coronary Artery Disease.

J Am Heart Assoc 2019 Jan;8(2):e011207

1 Department of Diabetes, Endocrinology, and Metabolism Center Hospital National Center for Global Health and Medicine Tokyo Japan.

Background This study aimed to assess whether the plasminogen activator inhibitor-1/tissue plasminogen activator ( PAI -1/ tPA ) ratio as a prothrombotic state is useful for optimizing cardiac treatment strategy. Methods and Results Using BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) trial data, we used a Cox proportional hazard model to calculate hazard ratios with 95% CI s for cardiac events in patients receiving early revascularization (percutaneous coronary intervention or coronary artery bypass grafting) or medical therapy, separately in patients with low (n=1276) and high (n=894) PAI -1/ tPA ratios. The primary outcome was major cardiac events, which was a composite end point including cardiac death and nonfatal myocardial infarction. Read More

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https://www.ahajournals.org/doi/10.1161/JAHA.118.011207
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http://dx.doi.org/10.1161/JAHA.118.011207DOI Listing
January 2019
2 Reads

Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction in China: Results From the China PEACE Prospective Study of Percutaneous Coronary Intervention.

JAMA Netw Open 2018 Dec 7;1(8):e185446. Epub 2018 Dec 7.

National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, People's Republic of China.

Importance: Despite a rapid increase in percutaneous coronary intervention (PCI) procedures in China, little is known about patient-reported health status before and after PCI in patients without acute myocardial infarction (AMI).

Objective: To describe self-perceived angina-specific health status prior to PCI and 1 year after the procedure in patients without AMI in China.

Design, Setting, And Participants: The China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE) Prospective Study of PCI was a population-based, multicenter cohort study of a consecutive sample of 1611 patients without AMI undergoing elective PCI. Read More

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http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
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http://dx.doi.org/10.1001/jamanetworkopen.2018.5446DOI Listing
December 2018
3 Reads

Temporal trends in prevalence and antithrombotic treatment among Asians with atrial fibrillation undergoing percutaneous coronary intervention: A nationwide Korean population-based study.

PLoS One 2019 15;14(1):e0209593. Epub 2019 Jan 15.

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, United Kingdom.

Background: We investigated the recent 10-year trends in the number of patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention (PCI) in relation to prescription patterns of antithrombotic therapy.

Methods: We analyzed the annual prevalence of PCI and patterns of antithrombotic therapy after PCI, including antiplatelets and oral anticoagulants (vitamin K antagonists and non-vitamin K antagonist oral anticoagulants [NOACs]), in patients with AF between 2006 and 2015 by using the Korean National Health Insurance Service database. Independent factors associated with triple therapy (oral anticoagulant plus dual antiplatelet) prescription were assessed using multivariable logistic regression analysis. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0209593PLOS
January 2019
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Dual Anti-Thrombotic Therapy With Dabigatran After Percutaneous Coronary Intervention in Atrial Fibrillation - Japanese and East-Asian Subgroup Analysis of the RE-DUAL PCI Trial.

Circ J 2019 Jan 11. Epub 2019 Jan 11.

Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine.

Background: In the RE-DUAL PCI trial, dual anti-thrombotic therapy with dabigatran and a P2Yinhibitor had a lower risk of bleeding and similar risk reduction of thromboembolic events, compared with warfarin triple therapy, in patients with NVAF undergoing PCI. This subanalysis investigated whether the efficacy and safety of dabigatran dual therapy in Japanese and East-Asian patients enrolled in the RE-DUAL PCI trial were similar to those of the overall patient population of the trial. Methods and Results: RE-DUAL PCI was a multicenter, randomized trial. Read More

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http://dx.doi.org/10.1253/circj.CJ-18-0874DOI Listing
January 2019

A Long-Term Single-Center Registry of 6893 Patients Undergoing Elective Percutaneous Coronary Intervention With the Xience Everolimus-Eluting Stent.

J Invasive Cardiol 2019 Jan 15. Epub 2019 Jan 15.

Centro Cardiologico Monzino, Via Parea 4, 20138 Milan, Italy.

Background: The safety and effectiveness of the everolimus-eluting stent (EES) have been previously demonstrated.

Aims: To assess very long-term performance and outcomes of the EES in a real-world population.

Methods: This single-center registry prospectively enrolled 6893 patients (mean age, 66 ± 9. Read More

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January 2019
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Frequency and Outcomes of Ad Hoc Versus Planned Chronic Total Occlusion Percutaneous Coronary Intervention: Multicenter Experience.

J Invasive Cardiol 2019 Jan 15. Epub 2019 Jan 15.

Minneapolis Heart Institute, 920 E. 28th Street #300, Minneapolis, MN 55407 USA.

Background: For patients needing coronary chronic total occlusion (CTO) percutaneous coronary intervention (PCI), a planned, staged intervention has been recommended by experts. Ad hoc CTO-PCI, however, occurs in practice.

Methods: Observational, contemporary, multicenter, international registry. Read More

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January 2019
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In-Hospital Outcomes of Rotational Atherectomy in High-Risk Patients With Severely Calcified Left Main Coronary Artery Disease: A Single-Center Experience.

J Invasive Cardiol 2019 Jan 15. Epub 2019 Jan 15.

Division of Cardiovascular Medicine, Keck School of Medicine, 1510 San Pablo Street, Suite 322, Los Angeles, CA 90033 USA.

Background: Severe coronary artery calcification is a challenge for percutaneous coronary intervention (PCI), particularly in left main coronary artery disease (LM-CAD). Rotational atherectomy (RA) is a useful tool for modification of calcified plaque prior to PCI. We report our experience with RA for severely calcified LM-CAD. Read More

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January 2019

Size of Anterior Wall Acute Myocardial Infarction Treated by Primary Percutaneous Coronary Intervention in United States Versus Europe/Australia Versus India (from the CRISP-AMI Randomized Controlled Trial).

Am J Cardiol 2019 Jan 4. Epub 2019 Jan 4.

Duke Clinical Research Institute, Durham, North Carolina; Duke University Medical Center, Durham, North Carolina. Electronic address:

International variability in infarct size following acute anterior ST-elevation myocardial infarction without shock treated with primary percutaneous coronary intervention (PCI) has been little studied. Patients enrolled in the Counterpulsation to Reduce Infarct Size pre-PCI for Acute Myocardial Infarction international randomized trial were analyzed according to their region of enrollment: United States (US) (n = 60), Europe/Australia (EU/AU) (n = 104), or India (n = 123). Cardiac magnetic resonance imaging was performed 3-5 days after PCI to assess infarct size, expressed as percentage of left ventricular mass, and analyzed by an imaging core laboratory. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029149193003
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http://dx.doi.org/10.1016/j.amjcard.2018.12.027DOI Listing
January 2019
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Association of Statewide Certificate of Need Regulations With Percutaneous Coronary Intervention Appropriateness and Outcomes.

J Am Heart Assoc 2019 Jan;8(2):e010373

2 Center for Outcomes Research and Evaluation Yale-New Haven Hospital New Haven CT.

Background Certificate of need ( CON ) regulations are intended to coordinate new healthcare services, limit expansion of unnecessary new infrastructure, and limit healthcare costs. However, there is limited information about the association of CON regulations with the appropriateness and outcomes of percutaneous coronary interventions ( PCI ). The study sought to characterize the association between state CON regulations and PCI appropriateness. Read More

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https://www.ahajournals.org/doi/10.1161/JAHA.118.010373
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http://dx.doi.org/10.1161/JAHA.118.010373DOI Listing
January 2019
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Appropriateness of Percutaneous Coronary Intervention: Appropriate Use Criteria Outperform Certificate of Need.

J Am Heart Assoc 2019 Jan;8(2):e011661

1 University of Texas Health Science Center McGovern Medical School Memorial Hermann Heart & Vascular Institute Houston TX.

See Article by Chui et al. Read More

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http://dx.doi.org/10.1161/JAHA.118.011661DOI Listing
January 2019

Exercise training for patients with type 2 diabetes and cardiovascular disease: What to pursue and how to do it. A Position Paper of the European Association of Preventive Cardiology (EAPC).

Eur J Prev Cardiol 2019 Jan 14:2047487318820420. Epub 2019 Jan 14.

17 University Cardiology Department and Heart Failure Unit and Cardiopulmonary Laboratory, Cardiology, I.R.C.C.S., Milan, Italy.

Patients with type 2 diabetes mellitus suffer from dysregulation of a plethora of cardiovascular and metabolic functions, including dysglycaemia, dyslipidaemia, arterial hypertension, obesity and a reduced cardiorespiratory fitness. Exercise training has the potential to improve many of these functions, such as insulin sensitivity, lipid profile, vascular reactivity and cardiorespiratory fitness, particularly in type 2 diabetes mellitus patients with cardiovascular comorbidities, such as patients that suffered from an acute myocardial infarction, or after a coronary intervention such as percutaneous coronary intervention or coronary artery bypass grafting. The present position paper aims to provide recommendations for prescription of exercise training in patients with both type 2 diabetes mellitus and cardiovascular disease. Read More

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http://journals.sagepub.com/doi/10.1177/2047487318820420
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http://dx.doi.org/10.1177/2047487318820420DOI Listing
January 2019
10 Reads