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Transplantation 2022 Jun 30. Epub 2022 Jun 30.

Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Background: Biliary strictures frequently occur in living-donor liver transplant (LDLT) recipients. However, long-term clinical outcomes and their associated factors are unclear.

Methods: We analyzed an historical cohort of 228 recipients who underwent LDLT with post-liver transplantation biliary strictures. Read More

World J Gastrointest Endosc 2022 May;14(5):291-301

Unité d'Endoscopie Digestive, Hôpital Privé "Armand Brillard" 3/5 avenue Watteau, Nogent-sur-Marne 94130, France.

The differential diagnosis between benign and malignant biliary strictures is challenging and requires a multidisciplinary approach with the use of serum biomarkers, imaging techniques, and several modalities of endoscopic or percutaneous tissue sampling. The diagnosis of biliary strictures consists of laboratory markers, and invasive and non-invasive imaging examinations such as computed tomography (CT), contrast-enhanced magnetic resonance cholangiopancreatography, and endoscopic ultrasonography (EUS). Nevertheless, invasive imaging modalities combined with tissue sampling are usually required to confirm the diagnosis of suspected malignant biliary strictures, while pathological diagnosis is mandatory to decide the optimal therapeutic strategy. Read More

Gastrointest Endosc Clin N Am 2022 Jul 11;32(3):493-505. Epub 2022 May 11.

Division of Vascular and Interventional Radiology, Department of Radiology and Radiological Sciences, Johns Hopkins School of Medicine, 1800 Orleans Street, Sheik Zayed Tower, Suite 7203, Baltimore, MD 21287, USA. Electronic address:

Percutaneous biliary interventions (PBIs) are commonly performed by interventional radiologists for a variety of clinical indications including biliary infections, strictures, leaks, and postoperative complications. PBIs have high technical and clinical success rates and are relatively safe when compared with more invasive surgical techniques. Percutaneous transhepatic cholangiography and percutaneous biliary drainage play an essential role in the management of common posthepatobiliary complications including biliary strictures and leaks. Read More

Khirurgiia (Mosk) 2022 (6):18-26

Sklifosovsky Clinical and Research Institute for Emergency Care, Moscow, Russia.

Objective: To evaluate the efficacy of endoscopic retrograde stenting of the pancreatic duct for acute severe pancreatitis.

Material And Methods: We analyzed 94 patients with acute severe pancreatitis who underwent surgery (=87, 92.6%) and endoscopic retrograde pancreatic stenting (=28, 29. Read More

J Gastrointest Cancer 2022 May 24. Epub 2022 May 24.

Department of Gastroenterology and Hepatology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.

Background And Aim: Malignant biliary obstruction is an ominous complication of metastatic colorectal cancer (mCRC) that is challenging to solve. Biliary drainage can be performed to relieve symptoms of jaundice, treat cholangitis, or enable palliative systemic therapy. The aim of this study is to evaluate clinical outcomes of biliary drainage of malignant biliary obstruction in mCRC patients. Read More

Transpl Int 2022 22;35:10044. Epub 2022 Apr 22.

Department of Surgery, Seoul National University College of Medicine, Seoul, South Korea.

This study evaluated endoscopic retrograde cholangiopancreatography (ERCP) and percutaneous transhepatic biliary drainage (PTBD) as interventions for patients with anastomotic biliary complications (ABC) after living donor liver transplantation (LDLT). Prospectively collected data of patients who were diagnosed with ABC after LDLT between January 2013 and June 2017 were retrospectively reviewed. There were 57 patients who underwent LDLT with a right liver graft using duct-to-duct biliary reconstruction and experienced ABC. Read More

Am J Surg 2022 Apr 29. Epub 2022 Apr 29.

Trauma Unit Shamir Medical Center Affiliated with University Tel Aviv, Zerefin, Israel. Electronic address:

J Clin Med 2022 Apr 2;11(7). Epub 2022 Apr 2.

Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 06230, Korea.

Background: Intraductal papillary neoplasm of the bile duct (IPNB) is a precancerous lesion of cholangiocarcinoma, for which surgical resection is the most effective treatment. We evaluated the predictors of malignancy in IPNB according to anatomical location and the prognosis without surgery.

Methods: A total of 196 IPNB patients who underwent pathologic confirmation by surgical resection or endoscopic retrograde cholangiography or percutaneous transhepatic cholangioscopic biopsy were included. Read More

Radiol Case Rep 2022 Jun 4;17(6):1890-1896. Epub 2022 Apr 4.

Adv Train Gastroint & Organ Transp Surgery, 12 Scotland Street Dunedin, 9016, New Zealand.

Management of multiple hepatolithiasis with choledochoenteral anastomotic stenosis remains difficult and time-consuming. We report a case of a 77-year-old man with severe right hypochondoralgia, treated with percutaneous transhepatic balloon dilatation of choledocoduodenal anastomotic stenosis and percutaneous stone removal using 8Fr. cobra-shaped sheath and cholangioscopy. Read More

Acta Med Indones 2022 Jan;54(1):151-157

Faculty of Medicine Universitas Mataram - West Nusa Tenggara, Indonesia.

Cholelithiasis refers to a condition in which hardened deposits exist within the gall bladder. These deposits are also known as gallstones. Among other gastrointestinal diseases, Cholelithiasis is associated with the highest hospital admissions. Read More

Dig Dis Sci 2022 05 4;67(5):1649-1659. Epub 2022 Apr 4.

Division of Gastroenterology, Rutgers Robert Wood Johnson University Hospital, 1 RWJ Place, MEB 464, New Brunswick, NJ, 08901, USA.

Pancreaticobiliary (PB) endotherapy continues to progress in the era of therapeutic endosonography. Endoscopic retrograde cholangiopancreatography (ERCP) remains the primary method for PB access in native and altered anatomy. In altered anatomy, PB access can be obtained via enteroscopy-assisted ERCP (e-ERCP) or laparoscopy-assisted ERCP; however, both approaches have significant limitations. Read More

Medicine (Baltimore) 2022 Mar;101(11)

Shonan Gastroenterology Medicine Center, Shonan Kamakura General Hospital, Okamoto 1370-1, Kamakura, Kanagawa, Japan,Department of General Surgery, Shonan Kamakura General Hospital, Okamoto 1370-1, Kamakura, Kanagawa, Japan,Department of Emergency, Shonan Kamakura General Hospital, Okamoto 1370-1, Kamakura, Kanagawa, Japan.

Rationale: Simple liver cysts are common, and usually benign and asymptomatic, requiring little to no treatment. Liver cysts with biliary communication, however, are rare and require effective treatment to avoid recurrence.

Patient Concerns: A 70-year-old woman with breast cancer visited our hospital for treatment. Read More

Exp Clin Transplant 2022 03;20(3):316-320

From the Department of Surgery, Kosin University Gospel Hospital, Kosin University College of Medicine, Busan, Korea.

Survival after liver transplant has progressively improved over recent decades. Recurrent or de novo malignancy, however, remains a major cause of patient death after transplant. Here, we have described a patient who developed de novo intrahepatic cholangiocarcinoma in the graft liver after orthotopic liver transplant. Read More

Medicina (Kaunas) 2022 Feb 22;58(3). Epub 2022 Feb 22.

Digestive Endoscopy Unit, Department of Gastroenterology, Humanitas Clinical and Research Center, IRCCS, 20089 Rozzano, Milan, Italy.

Endoscopic retrograde cholangiopancreatography (ERCP) is considered as the first option in the management of malignant biliary obstruction. In case of ERCP failure, percutaneous transhepatic biliary drainage (PTBD) has been conventionally considered as the preferred rescue strategy. However, the use of endoscopic ultrasound (EUS) for biliary drainage (EUS-BD) has proved similarly high rates of technical success, when compared to PTBD. Read More

Acta Biomed 2022 03 14;93(1):e2022020. Epub 2022 Mar 14.

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In patients with symptomatic intrahepatic biliary lithiasis, the treatment is usually discussed by a multidisciplinary team. Although hepatectomy is considered as definitive treatment, when lobar atrophy is absent, endoscopic procedures are frequently proposed as first-line treatment due the low invasiveness and for sparing liver parenchyma. Percutaneous route is used in case of peroral approach failure. Read More

Quant Imaging Med Surg 2022 Mar;12(3):1698-1705

Department of Hepatobiliary Surgery, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine, Nanjing, China.

Background: Cholangitis after endoscopic retrograde cholangiopancreatography (ERCP) is a major problem for patients with hilar biliary obstruction. To date, it remains unclear whether air-contrast cholangiography (ACC) can reduce cholangitis in these patients. For this reason, our study assesses the efficacy of reducing cholangitis through ACC. Read More

Zhonghua Nei Ke Za Zhi 2022 Mar;61(3):263-268

Common bile duct (CBD) stone is a prevalent disease. As a novel treatment for CBD stone in China, percutaneous transhepatic papillary balloon dilation (PTPBD) has shown some advantages compared with other modalities. However, many components of the procedure remains unclear, including indications, contraindications, patient preparation, bile duct puncture, papillary dilation, imaging interpretation, and complication management. Read More

Cureus 2022 Mar 2;14(3):e22761. Epub 2022 Mar 2.

Department of Surgical Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, IND.

Background and objective Percutaneous balloon dilatation followed by long-term internal-external biliary catheter (IEBC) placement is the standard radiological management for postoperative hepaticojejunostomy (HJ) strictures. The treatment is considered successful when cholangiography shows a free flow of contrast across the anastomosis and the patient passes a "clinical test". However, these tests may not be suitable predictors of long-term successful treatment outcomes. Read More

Pediatr Radiol 2022 05 2;52(6):1075-1085. Epub 2022 Mar 2.

Department of Medical Ultrasonics, First Affiliated Hospital, Institute for Diagnostic and Interventional Ultrasound, Sun Yat-Sen University, 58 Zhongshan Road 2, Guangzhou, 510080, People's Republic of China.

Background: Percutaneous ultrasound (US)-guided cholecystocholangiography is effective in diagnosing biliary atresia for infants with a gallbladder >1.5 cm in length on US. However, whether it is still effective for other types of gallbladders needs further clarification. Read More

S Afr Med J 2021 Aug 2;111(8):803-808. Epub 2021 Aug 2.

Department of Surgery, Nelson R Mandela School of Medicine, College of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Background: Early diagnosis of biliary infection is critical for timely antimicrobial therapy and biliary drainage. HIV infection may influence the spectrum and severity of biliary infection in an environment with a high HIV prevalence. Charcot's triad has low sensitivity and higher specificity for biliary infection, and more sensitive markers are required. Read More

Cardiovasc Intervent Radiol 2022 Jun 23;45(6):867-872. Epub 2022 Feb 23.

Department of Radiology, Papa Giovanni XXIII Hospital, Piazza OMS 1, 24127, Bergamo, Italy.

Purpose: Cholestasis due to benign biliary strictures is the most common biliary complication after pediatric split liver transplantation (SLT), decreasing graft survival, but consensus about its management lacks. Percutaneous transhepatic cholangiography, bilioplasty and internal-external biliary drainage (IEBD) are standard treatments. The aim of this report is to present the preliminary experience with a new biodegradable biliary stent in the management of post-SLT biliary strictures. Read More

Eur J Obstet Gynecol Reprod Biol 2022 Apr 8;271:132-137. Epub 2022 Feb 8.

Department of Fetal-Maternal Medicine, Nagara Medical Center, 1300-7 Nagara, Gifu, Japan; Division of Obstetrics and Gynecology, Matsunami General Hospital, 185-1, Tashiro, Kasamatsu-cho, Hashima, Gifu, Japan.

Objective: Transabdominal amnioinfusion is beneficial in oligohydramnios, which has high fetal mortality and does not improve with observation alone. However, there are few reports on the maternal adverse events of transabdominal amnioinfusion. This study aimed to evaluate the adverse events of amniocentesis with transabdominal amnioinfusion. Read More

Arab J Gastroenterol 2022 Feb 10;23(1):32-38. Epub 2022 Feb 10.

Department of Gastroenterology, Yuebei People's Hospital, Shaoguan, Guangdong 512025, China.

Background And Study Aims: A full understanding of the clinical manifestations and risk factors for hepatic abscesses with biloma formation after transcatheter arterial chemoembolization (TACE) is crucial for accurate diagnosis and effective therapeutic intervention.

Patients And Methods: 11,524 patients with hepatic tumors were treated with TACE. 84 patients were diagnosed with hepatic abscesses after TACE, and 35 progressed to hepatic bilomas and were treated with percutaneous transhepatic drainage (PTD) and/or percutaneous transhepatic cholangiography and drainage (PTCD). Read More

Pan Afr Med J 2021 15;40:224. Epub 2021 Dec 15.

Department of Surgery, Muhimbili National Hospital, Dar es Salaam, Tanzania.

Choledochal cyst are rare congenital disease of the biliary tree. It presenting as cystic dilatations of the biliary tree can involve the extrahepatic biliary radicles, the intrahepatic biliary radicles or both. They are typically a surgical problem of infancy and childhood, but less than a quarter of the patients the diagnosis is delayed until adulthood as it presenting with vague and nonspecific signs and symptoms. Read More

J Gastrointest Cancer 2022 Jun 2;53(2):496-501. Epub 2022 Feb 2.

Manisa Celal Bayar University, Medical Oncology Department, Manisa, Turkey.

Purpose: Gastric cancer is one of the biologically aggressive and highly mortal cancers. In addition to limited treatment options, especially in advanced stages, palliative treatment methods are applied to increase patients' quality of life with gastric cancer. This study aims to discuss the effects of paracentesis, thoracentesis, tube thoracostomy, double J catheter nephrostomy, percutaneous transhepatic cholangiography (PTC), and abscess drainage catheter placement procedures applied in the last 3 months for problems requiring palliation, in the light of literature. Read More

Pediatr Radiol 2022 05 2;52(6):1061-1074. Epub 2022 Feb 2.

Department of Radiology, ASST Papa Giovanni XXIII Hospital, 24127, Bergamo, Italy.

Background: Although biliary complications after orthotopic liver transplantation represent a common source of morbidity and mortality, decreasing graft survival, consensus is lacking on their management in the pediatric population.

Objective: The aim of this study was to present the prevalence of such biliary complications and their interventional radiologic management with representative images.

Materials And Methods: This retrospective study reports our experience with percutaneous transhepatic cholangiography in the management of biliary complications after orthotopic liver transplantation in pediatric patients. Read More

Endosc Ultrasound 2022 Jan-Feb;11(1):4-16

Division of Gastroenterology, Centura Healthcare, Denver, Colorado, CO, USA.

EUS-guided biliary drainage (EUS-BD) and percutaneous transhepatic cholangiography biliary drainage (PTC) are the two alternate methods for biliary decompression in cases where ERCP fails. We conducted a systematic review and meta-analysis of studies to compare the efficacy and safety of endoscopic and percutaneous biliary drainage for malignant biliary obstruction in patients with failed ERCP. A total of ten studies were included, fulfilling the inclusion criteria, including four retrospective studies and six randomized controlled trials. Read More

J Clin Exp Hepatol 2022 Jan-Feb;12(1):129-134. Epub 2021 Mar 19.

SIMS Institute of Gastroenterology, Hepatology and Transplantation, SRM Institutes for Medical Science, India.

Background: Single-session endoscopic stone extraction (ESE) and laparoscopic cholecystectomy (LC) has the best outcome in managing concomitant cholelithiasis (gallstone disease [GSD]) and choledocholithiasis (common bile duct stone [CBDS]). Traditional rendezvous technique with an intraoperative cholangiogram is associated with various technical (bowel distention, frozen Calot's triangle, limitation of intraoperative cholangiogram and so on) and logistical difficulties (lack of trained personnel and equipment for ESE in the operating room). We modified our approach of ESE-LC (tandem ESE-LC) to study the safety of the approach and overcome these disadvantages of the traditional rendezvous approach. Read More

Medicine (Baltimore) 2022 Jan;101(3):e28478

Department of Hepatobiliary Surgery, Binzhou Medical University Hospital, Binzhou, China.

Rationale: Cholangiocarcinoma is a common cause of obstructive jaundice but is mainly associated with solid mass and not semisolid secretion. In this report, the patient was admitted to the hospital with obstructive jaundice; however, no solid mass was found to lead to jaundice.

Patient Concerns: The patient developed symptoms of obstructive jaundice for 10 days, including fatigue and yellow skin staining. Read More

Clin Transplant 2022 May 27;36(5):e14597. Epub 2022 Jan 27.

Division of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.

Background: For primary sclerosing cholangitis (PSC) patients undergoing liver transplantation (LT), a consensus regarding biliary reconstruction remains unresolved. Choledochoduodenostomy (CDD) represents an alternative to Roux-en-Y (RY) and duct-to-duct. We compared long-term post-transplant outcomes between CDD and RY. Read More