148,960 results match your criteria Percutaneous Absess Drainage


Radial versus femoral artery access for percutaneous coronary artery intervention in patients with acute myocardial infarction and multivessel disease complicated by cardiogenic shock: Subanalysis from the CULPRIT-SHOCK trial.

Am Heart J 2020 Apr 30;225:60-68. Epub 2020 Apr 30.

First Department of Medicine-Cardiology, University Medical Centre Mannheim (UMM), University of Heidelberg, Mannheim, Germany.

Background: The use and impact of transradial artery access (TRA) compared to transfemoral artery access (TFA) in patients undergoing percutaneous coronary intervention (PCI) for acute myocardial infarction (MI) complicated by cardiogenic shock (CS) remain unclear.

Methods: This is a post hoc analysis of the CULPRIT-SHOCK trial where patients presenting with MI and multivessel disease complicated by CS were randomized to a strategy of culprit-lesion-only or immediate multivessel PCI. Arterial access was left at operator's discretion. Read More

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http://dx.doi.org/10.1016/j.ahj.2020.04.014DOI Listing

Special Communication: Evaluation and Treatment of Thoracic Outlet Syndrome During the Global Pandemic Due to SARS-CoV-2 and COVID-19.

J Vasc Surg 2020 Jun 1. Epub 2020 Jun 1.

The Center for Thoracic Outlet Syndrome and the Section of Vascular Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO. Electronic address:

The global SARS-CoV-2/COVID-19 pandemic has required a reduction in non-emergency treatment for a variety of disorders. This report summarizes conclusions of an international multidisciplinary consensus group assembled to address evaluation and treatment of patients with thoracic outlet syndrome (TOS), a group of conditions characterized by extrinsic compression of the neurovascular structures serving the upper extremity. The following recommendations were developed in relation to the 3 defined types of TOS (neurogenic, venous, and arterial) and 3 phases of pandemic response (preparatory, urgent with limited resources, and emergency with complete diversion of resources): (1) In-person evaluation and treatment for neurogenic TOS (interventional or surgical) is generally postponed during all pandemic phases, with telephone/telemedicine visits and at-home physical therapy exercises recommended when feasible. Read More

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http://dx.doi.org/10.1016/j.jvs.2020.05.048DOI Listing

Is Routine Postoperative Anticoagulation Necessary In All Patients After First Rib Resection for Paget-Schroetter Syndrome?

Ann Vasc Surg 2020 Jun 1. Epub 2020 Jun 1.

University of Pennsylvania School of Medicine, Hospital of the University of Pennsylvania.

Objectives: Definitive treatment of Paget-Schroetter syndrome (PSS) involves first rib resection (FRR),division of the anterior scalene muscle, and resection of the subclavius muscle. This is a single institution experience with PSS, according to a treatment algorithm of preoperative venogram (accompanied by lysis and percutaneous mechanical thrombectomy as needed) followed by transaxillary FRR. In the later period of this experience, patients have often been discharged on aspirin only, with no plan for anticoagulation postoperatively. Read More

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http://dx.doi.org/10.1016/j.avsg.2020.05.042DOI Listing

Coronary angiography and percutaneous coronary intervention after transcatheter aortic valve replacement with medtronic self-expanding prosthesis: Insights from correlations with computer tomography.

Int J Cardiol 2020 Jun 1. Epub 2020 Jun 1.

Division of Cardiology, Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai, NY, New York, United States of America. Electronic address:

Objectives: We aim to describe the feasibility, challenges, success rates and techniques utilized in coronary angiography (CA) and percutaneous coronary intervention (PCI) in patients post transcatheter aortic valve replacement (TAVR).

Background: CA and PCI after TAVR are becoming increasingly encountered in clinical practice. There have been technical difficulties reported in re-accessing the coronary arteries through the self-expanding CoreValve prosthesis. Read More

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http://dx.doi.org/10.1016/j.ijcard.2020.05.065DOI Listing

Transcatheter aortic valve replacement in patients with a history of cancer: Periprocedural and long-term outcomes.

Catheter Cardiovasc Interv 2020 Jun 4. Epub 2020 Jun 4.

Department of Cardiology, Austin Health, Melbourne, Victoria, Australia.

Background: A history of cancer is incorporated into the surgical risk assessment of patients undergoing surgical aortic valve replacement through the Society for Thoracic Surgeons score. However, the prognostic significance of cancer in patients treated with transcatheter aortic valve replacement (TAVR) is unclear. As the cancer survivorship population increases, it is imperative to establish the efficacy and safety of TAVR in patients with severe symptomatic aortic stenosis (AS) and a history of malignancy. Read More

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http://dx.doi.org/10.1002/ccd.28969DOI Listing

Pulmonary Artery Thrombectomy - A Life Saving Treatment in a Patient with Presumed COVID-19 complicated by a massive Pulmonary Embolus.

Br J Haematol 2020 Jun 4. Epub 2020 Jun 4.

Interventional Radiology, Southmead Hospital, North Bristol Trust, Bristol, BS10 5NB, United Kingdom.

To our knowledge, we report the first case of percutaneous pulmonary thrombectomy and catheter directed thrombolysis for massive pulmonary embolism (PE) in a patient with presumed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Standard treatments of anticoagulation and systemic thrombolysis were unsuccessful and the patient continued to deteriorate. Percutaneous pulmonary thrombectomy and locally delivered thrombolysis was a life-saving treatment; the patient continues to improve and is currently being nursed on a standard ward. Read More

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http://dx.doi.org/10.1111/bjh.16920DOI Listing

Three-dimensionally printed non-biological simulator for percutaneous nephrolithotomy training.

Scand J Urol 2020 Jun 4:1-6. Epub 2020 Jun 4.

Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia.

We sought to improve the educational and pre-operative training on various stages of percutaneous nephrolithotomy (PCNL) under fluoroscopic and ultrasound guidance. We developed a three-dimensional (3D) printed simulator (3D-printed PCNL model) for urological trainees. 40 s year urology residents were randomly assigned into two groups, completing PCNL surgical steps on a URO Mentor™ surgical simulator (Group A) or on our new 3D-printed PCNL model (Group B). Read More

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http://dx.doi.org/10.1080/21681805.2020.1773529DOI Listing

Artificial Vascular Graft Migration into Hollow Viscus Organs in Patients who Underwent Right Lobe Living Donor Liver Transplantation.

Acta Chir Belg 2020 Jun 4:1-18. Epub 2020 Jun 4.

Liver Transplant Institute, Inonu University, 44280, Malatya, Turkey.

To share our experience with hollow viscus migration of artificial vascular grafts (AVG) used for venous reconstruction of the right anterior sector in living donor liver transplantations (LDLT). Clinical, radiological, and endoscopic data of 13 right lobe LDLT patients (range: 26-67 years) with a diagnosis of postoperative AVG migration into adjacent hollow viscus were analyzed.: Biliary complications were detected in 12 patients. Read More

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Mechanical assist devices for acute cardiogenic shock.

Cochrane Database Syst Rev 2020 Jun 4;6:CD013002. Epub 2020 Jun 4.

Cardiothoracic Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Background: Cardiogenic shock (CS) is a state of critical end-organ hypoperfusion due to a primary cardiac disorder. For people with refractory CS despite maximal vasopressors, inotropic support and intra-aortic balloon pump, mortality approaches 100%. Mechanical assist devices provide mechanical circulatory support (MCS) which has the ability to maintain vital organ perfusion, to unload the failing ventricle thus reduce intracardiac filling pressures which reduces pulmonary congestion, myocardial wall stress and myocardial oxygen consumption. Read More

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http://dx.doi.org/10.1002/14651858.CD013002.pub2DOI Listing

The Effect of Atropine on Trigeminocardiac Reflex-induced Hemodynamic Changes During Therapeutic Compression of the Trigeminal Ganglion.

J Neurosurg Anesthesiol 2020 Jun 2. Epub 2020 Jun 2.

Second Department of Neurosurgery, People's Hospital of China Medical University (Liaoning Provical People's Hospital).

Background: Percutaneous compression of the trigeminal ganglion (PCTG) can induce significant hemodynamic perturbations secondary to the trigeminocardiac reflex (TCR). The aim of this study was to investigate the effect of atropine pretreatment on hemodynamic responses during PCTG for trigeminal neuralgia.

Materials And Methods: A total of 120 patients who received PCTG were randomly assigned to control and atropine groups that were pretreated with saline (n=60) and atropine 0. Read More

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http://dx.doi.org/10.1097/ANA.0000000000000702DOI Listing

Hepatic encephalopathy due to a congenital portosystemic shunt: a disease with a changeable presentation.

Rev Esp Enferm Dig 2020 Jun 4;112:508-509. Epub 2020 Jun 4.

Patología Digestiva, Consorcio Hospital General Universitario de Valencia.

The presence of congenital portosystemic shunts in adult patients is an uncommon entity that can manifests itself with hepatic encephalopathy symptoms. However, its clinical presentation can be very diverse and varied, hence it is essential to bear it in mind to be able to diagnose it. In this manuscript we exemplify this variability by presenting a patient with complex long-standing neurological syndrome of uncertain origin, that was finally diagnosed of portosystemic shunt. Read More

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http://dx.doi.org/10.17235/reed.2020.6665/2019DOI Listing

Left Distal Radial Artery Access Site in Primary Percutaneous Coronary Intervention: Is It Safe?

Balkan Med J 2020 Jun 4. Epub 2020 Jun 4.

Department of Cardiology, Ege University School of Medical, İzmir Turkey.

Background: Left distal radial artery (LDRA) access site has emerged as a new technique for coronary angiography procedures.

Aims: We aimed to assess its applicability as an alternative way for primary percutaneous coronary interventions in ST-Elevation Myocardial Infarction (STEMI).

Study Design: This study was a retrospective evaluation of consecutive STEMI patients intervened through the left distal radial artery access site. Read More

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http://dx.doi.org/10.4274/balkanmedj.galenos.2020.2020.4.49DOI Listing

Systematic Review and Network Meta-Analysis of Atrial Fibrillation Percutaneous Catheter Ablation Technologies using Randomised Controlled Trials.

J Cardiovasc Electrophysiol 2020 Jun 4. Epub 2020 Jun 4.

The Farr Institute of Health Informatics Research London, 222 Euston Road, London, NW1 2DA, UK.

Aims: We sought out to make comparisons between all atrial fibrillation (AF) catheter ablation technologies using randomised controlled trial data. Our comparisons were freedom from AF, procedural duration and fluoroscopy duration.

Methods: Searches were made of EMBASE, MEDLINE and CENTRAL databases and studies were selected which had Cryoballoon, conventional radiofrequency (RF), multipolar radiofrequency catheters and Laser technology as an arm in the study and were identified as randomised controlled trials (RCT). Read More

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http://dx.doi.org/10.1111/jce.14598DOI Listing

Epicardial standalone left atrial appendage clipping for prevention of ischemic stroke in patients with atrial fibrillation contraindicated for oral anticaogulation.

J Cardiovasc Electrophysiol 2020 Jun 4. Epub 2020 Jun 4.

Department of Cardiac Surgery, UZ Brussel, Brussels, Belgium.

Introduction: The most appropriate treatment for stroke prevention in stand-alone atrial fibrillation patients with a high CHADS2VASC score contraindicated for oral anticoagulation (OAC) or novel OAC (NOAC) still needs to be defined. Percutaneous left atrial appendage closure devices are available, but because of their endocardial positioning need a period of antiplatelet therapy. This study aimed to evaluate safety and efficacy of epicardial left atrial appendage clipping in patients contraindicated for (N)OAC and APT therapy. Read More

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http://dx.doi.org/10.1111/jce.14599DOI Listing

Non-ST-elevation myocardial infarction in the Netherlands: room for improvement!

Neth Heart J 2020 Jun 3. Epub 2020 Jun 3.

Department of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands.

Aim: To analyse non-ST-elevation myocardial infarction (NSTEMI) care in the Netherlands and to identify modifiable factors to improve NSTEMI healthcare.

Methods: This retrospective cohort study analysed hospital and pharmacy claims data of all NSTEMI patients in the Netherlands in 2015. The effect of percutaneous coronary intervention (PCI) during hospitalisation on 1‑year mortality was investigated in the subcohort alive 4 days after NSTEMI. Read More

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http://dx.doi.org/10.1007/s12471-020-01433-xDOI Listing

Right trisectionectomy for liver metastasis of granulosa cell tumor: a case report and literature review.

Surg Case Rep 2020 Jun 3;6(1):125. Epub 2020 Jun 3.

Department of Digestive and Transplantation Surgery, Tokyo Medical University Hachioji Medical Center, 1163 Tatemachi, Hachiojishi, Tokyo, 193-0998, Japan.

Background: Granulosa cell tumor (GCT) is a type of ovarian sex cord-stromal tumor with low-grade malignancy, which can recur long after primary resection. All reports on GCTs in the liver describe cases of metastases, while there are no previous reports of primary GCTs originating from the liver. We report a case of GCT, with recurrence of liver metastasis long after ovariectomy, which was subsequently resected by a right trisectionectomy. Read More

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http://dx.doi.org/10.1186/s40792-020-00880-3DOI Listing

Coronavirus disease 2019 (COVID-19) and simultaneous acute anteroseptal and inferior ST-segment elevation myocardial infarction.

Cardiovasc J Afr 2020 May 5;31:1-4. Epub 2020 May 5.

Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Istanbul Yeni Yuzyil University, Gaziosmanpasa Hospital, Gaziosmanpasa, Istanbul, Turkey.

Coronavirus disease 2019 (COVID-19) is a recently recognised pandemic spreading rapidly from Wuhan, Hubei, to other provinces in China and to many countries around the world. The number of COVID-19-related deaths is steadily increasing. Acute ST-segment elevation myocardial infarction (STEMI) is a disease with high morbidity and mortality rates, and primary percutaneous coronary intervention is usually recommended for the treatment. Read More

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http://dx.doi.org/10.5830-CVJA-2020-016DOI Listing

Severity of Coronary Artery Disease in Prediabetic Patients Undergoing Elective Coronary Angiography.

Cureus 2020 May 1;12(5):e7913. Epub 2020 May 1.

Medicine, Bahauddin Zakariya University, Multan, PAK.

Introduction Our objective was to determine the severity frequency of coronary artery disease (CAD) in prediabetes patients undergoing coronary angiography (CAG) in a catheterization laboratory. Materials and methods This descriptive comparative study was conducted on patients who were planned for elective CAG in the hospital from January 2019 to November 2019. The study includes patients age ≥40 years undergoing elective CAG with or without percutaneous coronary intervention/percutaneous transluminal coronary angioplasty. Read More

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http://dx.doi.org/10.7759/cureus.7913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263710PMC

Oral Anticoagulant Therapy: When What Should Not Be Is and What Should Be Is Not.

Authors:
James A Reiffel

J Innov Card Rhythm Manag 2019 Aug 15;10(8):3790-3792. Epub 2019 Aug 15.

Department of Medicine, Division of Cardiology, Electrophysiology Section, Columbia University, New York, NY, USA.

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http://dx.doi.org/10.19102/icrm.2019.100803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252818PMC

Comparing Transcatheter Aortic Valve Replacement (AVR) With Surgical AVR in Lower Risk Patients: A Comprehensive Meta-Analysis and Systematic Review.

Cardiol Res 2020 Jun 3;11(3):168-178. Epub 2020 May 3.

Department of Cardiology, Mercy Saint Vincent Medical Center, Toledo, OH 43608, USA.

Background: Transcutaneous aortic valve replacement (TAVR) is a novel percutaneous procedure for severe aortic stenosis and has been recently approved by Food and Drug Administration in lower risk patients. We performed the first ever meta-analysis and literature review of clinical trials comparing both 30-day and 1-year outcomes in lower risk patients undergoing TAVR vs. surgical aortic valve replacement (SAVR, having Society of Thoracic Surgeons score < 4% or equivalent). Read More

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http://dx.doi.org/10.14740/cr1046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239597PMC

Standardized approach to result analysis and interpretation of initial experience of coronary computed tomography angiography in a tertiary care hospital.

Pak J Med Sci 2020 May-Jun;36(4):683-688

Dr. Fatima Ahmad, Trainee Registrar Diagnostic Radiology. Department of Radiology, MTI-Lady Reading Hospital, Peshawar, Pakistan.

Objective: To have a systematic standardized approach to performing and interpretation of coronary CT Angiography (CTA) in order to maintain and enhance the diagnostic accuracy of the imaging modality.

Methods: This retrospective observational study was performed in Radiology Department, Lady Reading Hospital, Medical Teaching Institute, Peshawar, Pakistan from August 2018 to September 2019. Patients referred for coronary CT angiography were screened and prepared in radiology department. Read More

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http://dx.doi.org/10.12669/pjms.36.4.2174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260933PMC

Can antibiotic preference affect bleeding in percutaneous nephrolithotomy? Retrospective comparative study of two commonly used antibiotics.

Pak J Med Sci 2020 May-Jun;36(4):621-626

Murat Topcuoglu, Department of Urology, Faculty of Medicine, Alanya Alaaddin Keykubat University, Alanya, Turkey.

Objective: Bleeding is one of the most common and alarming complication of percutaneous nephrolithotomy (PCNL). In this study, we aimed to compare the effects of ciprofloxacin and cefuroxime on the bleeding in PCNL procedures.

Methods: The study was a retrospective analysis of 97 patients who underwent PCNL between February 2011 and June 2017. Read More

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http://dx.doi.org/10.12669/pjms.36.4.1977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260928PMC

Health-Related Quality of Life in Patients on Home Oxygen Therapy with Telemonitoring.

Yonago Acta Med 2020 May 16;63(2):132-134. Epub 2020 Apr 16.

Department of Pathobiological Science and Technology, Graduate School of Medical Sciences, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.

Home oxygen therapy (HOT) is an important treatment for patients with chronic respiratory diseases. Recently, telemonitoring of HOT has been become available. In the present study, we examined whether telemonitoring of HOT could improve health-related quality of life (HRQOL). Read More

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http://dx.doi.org/10.33160/yam.2020.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231879PMC

Computed Tomography-Guided Percutaneous Cryoablation for ‎ Subcardiac Hepatocellular Carcinoma: Safety, Efficacy, Therapeutic Results and Risk Factors for Survival Outcomes.

Cancer Manag Res 2020 12;12:3333-3342. Epub 2020 May 12.

Department of Interventional Radiology, Shandong Medical Imaging Research Institute, Affiliated to Shandong University, Jinan, Shandong, People's Republic of China.

Objective: To investigate the clinical safety, efficacy, therapeutic outcomes and risk factors of computed tomography-guided percutaneous cryoablation (CT-PCRA) for subcardiac hepatocellular carcinoma (HCC).

Patients And Methods: In this study, patients with single HCC nodules located on the left lobe who subsequently underwent CT-PCRA were reviewed from July 2012 to August 2016. According to the definition of subcardiac HCC, the patients were grouped into the subcardiac HCC group (n=33) and the non-subcardiac HCC group (n=40). Read More

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http://dx.doi.org/10.2147/CMAR.S250652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229785PMC

Embolization and sclerotherapy of maxillofacial arteriovenous malformations with the use of fibrin glue combined with pingyangmycin.

Oral Surg Oral Med Oral Pathol Oral Radiol 2020 May 31. Epub 2020 May 31.

Professor, State Key Laboratory of Military Stomatology and National Clinical Research Center for Oral Diseases and Shaanxi Clinical Research Center for Oral Diseases, Department of Head and Neck Tumor Surgery, School of Stomatology, The Air Force Military Medical University, Xi'an, Shaanxi, China. Electronic address:

Objective: The objectives of this study were to document the results of using fibrin glue (FG) combined with pingyangmycin (PYM) for the embolism and sclerotherapy of maxillofacial arteriovenous malformations (AVMs).

Study Design: We reviewed the associated clinical data from December 2012 to June 2017 for 25 patients with maxillofacial AVMs. The major treatment method was direct percutaneous puncture and injection of FG combined with PYM. Read More

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http://dx.doi.org/10.1016/j.oooo.2020.02.003DOI Listing

Self-limiting sternal tumors of childhood (SELSTOC): a diagnostic challenge.

Radiologia 2020 May 31. Epub 2020 May 31.

Hospital Universitario 12 de Octubre, Madrid, España.

Introduction: Self-limiting sternal tumors of childhood (SELSTOC) are rapidly growing sternal lesions that tend to resolve spontaneously. Patients have no history of infection, trauma, or neoplasms, and the most likely etiology is an aseptic inflammatory reaction of unknown origin. The differential diagnosis includes a wide spectrum of lesions such as tumors, infections, malformations, or anatomic variants. Read More

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http://dx.doi.org/10.1016/j.rx.2020.04.007DOI Listing

Improving clinical outcomes and patient satisfaction among patients with coronary artery disease: an example of enhancing regional integration between a cardiac centre and a referring hospital.

BMC Health Serv Res 2020 Jun 3;20(1):494. Epub 2020 Jun 3.

Catharina Ziekenhuis, Michelangelolaan 2, 5623 EJ, Eindhoven, The Netherlands.

Background: Value-based healthcare (VBHC) is a promising strategy to increase patient value. For a successful implementation of VBHC, intensive collaborations between organizations and integrated care delivery systems are key conditions. Our aim was to evaluate the effects of a pilot study regarding enhancing regional integration between a cardiac centre and a referring hospital on patient-relevant clinical outcomes and patient satisfaction. Read More

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http://dx.doi.org/10.1186/s12913-020-05352-wDOI Listing

Variability in blood lipids affects the neutrophil to lymphocyte ratio in patients undergoing elective percutaneous coronary intervention: a retrospective study.

Lipids Health Dis 2020 Jun 3;19(1):124. Epub 2020 Jun 3.

Department of Cardiovascular Diseases, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, No 3 East of Qinchun Road, Hangzhou, Zhejiang, 310000, People's Republic of China.

Background: Atherosclerosis is associated with chronic inflammation and lipid metabolism. The neutrophil to lymphocyte ratio (NLR) as an indicator of inflammation has been confirmed to be associated with cardiovascular disease prognosis. However, few studies have explored the effects of blood lipid variability on NLR. Read More

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http://dx.doi.org/10.1186/s12944-020-01304-9DOI Listing

Severe pain-related adverse events of percutaneous dilatational tracheostomy performed by a neurointensivist compared with conventional surgical tracheostomy in neurocritically ill patients.

BMC Neurol 2020 Jun 3;20(1):223. Epub 2020 Jun 3.

Department of Critical Care Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Background: We evaluated severe pain-related adverse events (SAE) during the percutaneous dilatational tracheostomy (PDT) procedure performed by a neurointensivist and compared the outcomes with that of conventional surgical tracheostomy in neurocritically ill patients.

Methods: This was a retrospective and observational study of adult patients who were admitted to the neurosurgical intensive care unit between January 2014 and March 2018 and underwent tracheostomy. In this study, primary endpoints were incidence of SAE: cardiac arrest, arrhythmias, hypertension, hypotension, desaturation, bradypnea, or ventilatory distress. Read More

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http://dx.doi.org/10.1186/s12883-020-01809-xDOI Listing

Bedside testing of CYP2C19 gene for treatment of patients with PCI with antiplatelet therapy.

BMC Cardiovasc Disord 2020 Jun 3;20(1):268. Epub 2020 Jun 3.

Department of Clinical Biochemistry, College of Medicine, Imam Abdulrahman bin Faisal University, Dammam, Saudi Arabia.

Background: To mitigate the risk of stent thrombosis, patients treated by percutaneous coronary intervention (PCI) are administered dual anti-platelet therapy comprising aspirin and a platelet P2Y receptor inhibitor. Clopidogrel is a prodrug requiring activation by the cytochrome P450 enzyme, CYP2C19. In Saudi Arabia, it has been reported that approximately 26% of the population carries CYP2C19*2 and/or *3 loss-of-function polymorphisms in addition to a high prevalence of CVD. Read More

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http://dx.doi.org/10.1186/s12872-020-01558-2DOI Listing

Characteristics of ST-elevation myocardial infarction with failed thrombolysis.

Asian Cardiovasc Thorac Ann 2020 Jun 3:218492320932074. Epub 2020 Jun 3.

UN Mehta Institute of Cardiology and Research Centre, Ahmedabad, Gujarat, India.

Background: Fibrinolytic therapy is an important reperfusion strategy, especially when primary percutaneous coronary interventions cannot be offered to ST-elevation myocardial infarction patients. Given that failed reperfusion after fibrinolytic therapy is common, it is pragmatic that the predictors, outcomes, and angiographic profiles of patients with failed thrombolysis are carefully scrutinized.

Methods: We prospectively studied clinical variables and outcomes over 30 months in 243 ST-elevation myocardial infarction patients who received fibrinolytics as primary treatment. Read More

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http://dx.doi.org/10.1177/0218492320932074DOI Listing

Endovascular therapy for erectile dysfunction: a state of the art review.

Minerva Cardioangiol 2020 Jun 2. Epub 2020 Jun 2.

Division of Cardiology, Clinica San Gaudenzio, Novara, Italy.

Erectile dysfunction (ED) is defined as the inability to attain or maintain penile erection sufficient for successful sexual intercourse. ED carries a notable influence on quality of life, with significant implications for family and social relationships. Because atherosclerosis of penile arteries represents one of the most frequent causes of ED, patients presenting with it should always be investigated for potential coexistent coronary or peripheral disease. Read More

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http://dx.doi.org/10.23736/S0026-4725.20.05136-1DOI Listing

Association between the ST segment resolution after primary angioplasty and short term outcomes in patients with acute myocardial infarction.

Minerva Cardioangiol 2020 Jun 2. Epub 2020 Jun 2.

Department of Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.

Background: The aim of this study was to evaluate the relationship between the early/late complete ST-resolution and short-term cardiovascular outcomes in patients undergoing primary angioplasty.

Methods: This was a prospective cross-sectional study of patients with acute myocardial infarction who candidate for primary percutaneous coronary intervention (PCI) during 1 year. An ECG obtained at the time of admission, 90 minutes and 24 hour after PCI. Read More

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http://dx.doi.org/10.23736/S0026-4725.20.05109-9DOI Listing

Adjunctive Cilostazol to Dual Antiplatelet Therapy to Enhance Mobilization of Endothelial Progenitor Cell in Patients with Acute Myocardial Infarction: A Randomized, Placebo-Controlled EPISODE Trial.

J Clin Med 2020 Jun 1;9(6). Epub 2020 Jun 1.

Department of Internal Medicine, School of Medicine, Gyeongsang National University, Jinju 52828, Korea.

Background: Endothelial progenitor cells (EPCs) have the potential to protect against atherothrombotic event occurrences. There are no data to evaluate the impact of cilostazol on EPC levels in high-risk patients.

Methods: We conducted a randomized, double-blind, placebo-controlled trial to assess the effect of adjunctive cilostazol on EPC mobilization and platelet reactivity in patients with acute myocardial infarction (AMI). Read More

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http://dx.doi.org/10.3390/jcm9061678DOI Listing

Short-Term Effects of PENS versus Dry Needling in Subjects with Unilateral Mechanical Neck Pain and Active Myofascial Trigger Points in Levator Scapulae Muscle: A Randomized Controlled Trial.

J Clin Med 2020 Jun 1;9(6). Epub 2020 Jun 1.

Physiotherapy and Pain Group, University of Alcalá, 28871 Madrid, Spain.

Procedures such as dry needling (DN) or percutaneous electrical nerve stimulation (PENS) are commonly proposed for the treatment of myofascial trigger points (MTrP). The aim of the present study is to investigate if PENS is more effective than DN in the short term in subjects with mechanical neck pain. This was an evaluator-blinded randomized controlled trial. Read More

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http://dx.doi.org/10.3390/jcm9061665DOI Listing

EUS-Guided Versus Percutaneous Celiac Neurolysis for the Management of Intractable Pain Due to Unresectable Pancreatic Cancer: A Randomized Clinical Trial.

J Clin Med 2020 Jun 1;9(6). Epub 2020 Jun 1.

Division of Gastroenterology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Korea.

Although endoscopic ultrasound-guided celiac neurolysis (EUS-CN) and percutaneous celiac neurolysis (PCN) are utilized to manage intractable pain in pancreatic cancer patients, no direct comparison has been made between the two methods. We compared the efficacy and safety of EUS-CN and PCN in managing intractable pain in such patients. Sixty pancreatic cancer patients with intractable pain were randomly assigned to EUS-CN ( = 30) or PCN ( = 30). Read More

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http://dx.doi.org/10.3390/jcm9061666DOI Listing

P2Y12 Inhibitor Monotherapy with Clopidogrel Versus Ticagrelor in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention.

J Clin Med 2020 Jun 1;9(6). Epub 2020 Jun 1.

Department of Internal Medicine, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 704, Taiwan.

Background: P2Y12 inhibitor monotherapy is an alternative antiplatelet strategy in patients undergoing percutaneous coronary intervention (PCI). However, the ideal P2Y12 inhibitor for monotherapy is unclear.

Methods And Results: We performed a multicenter, retrospective, observational study to compare the efficacy and safety of monotherapy with clopidogrel versus ticagrelor in patients with acute coronary syndrome (ACS) undergoing PCI. Read More

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http://dx.doi.org/10.3390/jcm9061657DOI Listing

Variability in the Method of Gastrostomy Placement in Children.

Children (Basel) 2020 Jun 1;7(6). Epub 2020 Jun 1.

Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Children's Wisconsin, Milwaukee, WI 53226, USA.

Although gastrostomy placement is one of the most common procedures performed in children, the optimal technique remains unclear. The purpose of this study was to evaluate variability in the method of gastrostomy tube placement in children in the United States. Patients <18 years old undergoing percutaneous endoscopic gastrostomy (PEG) or surgical gastrostomy (SG) (including open or laparoscopic) from 1997 to 2012 were identified using the Kids' Inpatient Database. Read More

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http://dx.doi.org/10.3390/children7060053DOI Listing

Multiple liver metastases of pulmonary carcinoid successfully treated by two-stage hepatectomy combined with embolization of portal vein branches: Report of a case.

Int J Surg Case Rep 2020 May 29;71:319-322. Epub 2020 May 29.

Department of Surgery, The Jikei University School of Medicine, 3-25-8 Nishi-shimbashi, Minato-ku, Tokyo, 105-8461, Japan. Electronic address:

Introduction: The prognosis of atypical pulmonary carcinoid with liver metastases is extremely poor, and patients with multiple liver metastases are often treated using non-surgical therapies. We report a case with multiple liver metastases from atypical pulmonary carcinoid that was successfully treated using two-stage hepatectomy combined with embolization of portal vein branches.

Presentation Of Case: A 48-year-old man was referred to our department after multiple liver tumors were detected in both liver lobes on computed tomography. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.05.043DOI Listing

Modified Full-Endoscopic Interlaminar Discectomy via an Inferior Endplate Approach for Lumbar Disc Herniation: Retrospective 3-Year Results from 321 Patients.

World Neurosurg 2020 May 31. Epub 2020 May 31.

Department of Spine surgery, the Third Affiliated Hospital of Southern Medical University, Guangzhou, China. Electronic address:

Background: Percutaneous endoscopic interlaminar discectomy (PEID) is widely used as a minimally invasive procedure that shows satisfying outcomes for the treatment of L5/S1 and even L4/5 disc herniation. PEID can be divided into direct and indirect approaches according to the established method of the working channel. The direct approach mainly utilizes the puncture needle directly through the intervertebral space into the intervertebral disc under non-direct vision and insertion of the guidewire into the puncture needle to guide the dilator and working channel to retract the ligamentum flavum, dural sac and nerve roots. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.05.234DOI Listing

Delivery routes for faecal microbiota transplants: Available, anticipated and aspired.

Pharmacol Res 2020 May 31:104954. Epub 2020 May 31.

School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab, 144411, India.

Fecal microbiota transplant (FMT) has seen a historic emergence in last decade with its sojourn recently entering into a chequered path, due to a few reports of infection and subsequent mortality. Though FMT has been extensively reported, there is no comprehensive report on the delivery routes available for this non-pharmacological treatment option. Safety, efficacy and cost of FMT not only depend on the quality of contents but also on the delivery route employed. Read More

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http://dx.doi.org/10.1016/j.phrs.2020.104954DOI Listing