1,542 results match your criteria Peptostreptococcus Infection

Prevalence and antibiotic susceptibility trends of periodontal pathogens in the subgingival microbiota of German periodontitis patients: A retrospective surveillance study.

J Clin Periodontol 2021 May 2. Epub 2021 May 2.

Division of Microbiology, Paul-Ehrlich-Institut, Paul-Ehrlichstr. 51-59, D-63225, Langen, Germany.

Objective: This retrospective surveillance study aimed to follow periodontitis-associated bacterial profiles and to identify time-dependent changes in antibiotic susceptibility patterns.

Materials And Methods: From 2008 to 2015 bacterial specimen from deep periodontal pockets were collected from a total of 7804 German adults diagnosed with periodontitis. Presence of selected bacteria was confirmed by anaerobic culture and nucleic acid amplification. Read More

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Penile bacteria associated with HIV seroconversion, inflammation, and immune cells.

JCI Insight 2021 Apr 22;6(8). Epub 2021 Apr 22.

Department of Environmental and Occupational Health, Milken Institute School of Public Health, George Washington University, Washington, DC, USA.

The foreskin is a site of heterosexual acquisition of HIV-1 among uncircumcised men. However, some men remain HIV-negative despite repeated, unprotected vaginal intercourse with HIV-positive partners, while others become infected after few exposures. The foreskin microbiome includes a diverse group of anaerobic bacteria that have been linked to HIV acquisition. Read More

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HPV infection and bacterial microbiota in the semen from healthy men.

BMC Infect Dis 2021 Apr 21;21(1):373. Epub 2021 Apr 21.

Department of Paediatrics, University of Turku & Turku University Hospital, Turku, Finland.

Background: Aberrant microbiota composition has been linked to disease development at numerous anatomical sites. Microbiota changes in reaction to viral infections, such as human papillomavirus (HPV), have been investigated almost exclusively in the female reproductive tract. However, HPV infection may also affect male health by reducing semen quality and fertility. Read More

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-Induced Necrotizing Fasciitis Complicated by Multidrug-Resistant Infection: Efficacy of Chemical Necrectomy Using 40% Benzoic Acid.

Int J Low Extrem Wounds 2021 Apr 15:15347346211004305. Epub 2021 Apr 15.

University Hospital Brno, Masaryk University, Jihomoravský, Czech Republic.

Necrotizing fasciitis is a life-threatening skin and soft tissue infection associated with high morbidity and mortality in adult patients. This infection can present as either type 1 infection caused by a mixed microflora (, , sp., and sp. Read More

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Multicentre study of the burden of multidrug-resistant bacteria in the aetiology of infected diabetic foot ulcers.

Afr J Lab Med 2021 23;10(1):1261. Epub 2021 Mar 23.

Department of Medical Microbiology and Parasitology, Obafemi Awolowo University Teaching Hospitals, Ile-Ife, Nigeria.

Background: Infected diabetic foot ulcer (IDFU) is a public health issue and the leading cause of non-traumatic limb amputation. Very few published data on IDFU exist in most West African countries.

Objective: The study investigated the aetiology and antibacterial drug resistance burden of IDFU in tertiary hospitals in Osun state, Nigeria, between July 2016 and April 2017. Read More

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Comparative analysis of the vaginal microbiome of Chinese women with Trichomonas vaginalis and mixed infection.

Microb Pathog 2021 Feb 16;154:104790. Epub 2021 Feb 16.

Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.

The high prevalence and serious long-term sequelae of Trichomonas vaginalis (TV) infection worldwide is of a particular concern; however, data regarding the differences in the composition of the vaginal microbiome in cases of single TV infection or mixed infections (i.e., presence of TV and bacterial vaginosis) are scarce. Read More

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February 2021

Depiction of Vaginal Microbiota in Women With High-Risk Human Papillomavirus Infection.

Front Public Health 2020 8;8:587298. Epub 2021 Jan 8.

Department of Oncologic Gynecology, The First Hospital of Jilin University, Changchun, China.

Persistent infection with the carcinogenic human papillomavirus (HPV) is a prerequisite for the progression of cervical lesions and cancer. A growing body of research has focused on the functional role of the vaginal microbiota in the persistence of HPV infection. Understanding the microbial composition and structure in women with high-risk (hr)-HPV infection may help reveal associations between the vaginal microbiota and HPV infection, and identify potential biomarkers. Read More

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Immunological design of commensal communities to treat intestinal infection and inflammation.

PLoS Pathog 2021 01 19;17(1):e1009191. Epub 2021 Jan 19.

MRC Centre for Molecular Bacteriology and Infection, Department of Infectious Disease, Imperial College London, London, United Kingdom.

The immunological impact of individual commensal species within the microbiota is poorly understood limiting the use of commensals to treat disease. Here, we systematically profile the immunological fingerprint of commensals from the major phyla in the human intestine (Actinobacteria, Bacteroidetes, Firmicutes and Proteobacteria) to reveal taxonomic patterns in immune activation and use this information to rationally design commensal communities to enhance antibacterial defenses and combat intestinal inflammation. We reveal that Bacteroidetes and Firmicutes have distinct effects on intestinal immunity by differentially inducing primary and secondary response genes. Read More

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January 2021

Cervicovaginal bacterial communities in reproductive-aged Tanzanian women with Schistosoma mansoni, Schistosoma haematobium, or without schistosome infection.

ISME J 2021 May 6;15(5):1539-1550. Epub 2021 Jan 6.

Center for Global Health, Weill Cornell Medicine, New York, NY, USA.

Schistosome infection is recognized as a potentially modifiable risk factor for HIV in women by the World Health Organization. Alterations in cervicovaginal bacteria have been associated with HIV acquisition and have not been studied in schistosome infection. We collected cervical swabs from Tanzanian women with and without S. Read More

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Late spinal infections following posterior spinal fusion in pediatric deformities: treatment using single-stage titanium implant exchange.

Spine Deform 2021 May 5;9(3):751-755. Epub 2021 Jan 5.

Department of Orthopedic Surgery, Center for Spinal Disorders At Nicklaus Children's Hospital, Miami, FL, 33155, USA.

Purpose: Late infection following posterior spinal fusion (PSF) for deformity is a leading cause of revision. The purpose of this study is to evaluate clinical and radiographic outcomes following a single-stage debridement and exchange of spinal implants with titanium in adolescent patients with late-onset infections following PSF METHODS: A retrospective review of prospectively collected data of adolescent patients with spinal deformity, who were surgically treated with PSF was collected. Patients were included for the study if they developed late arising infection (> 1 year after index posterior fusion for the deformity) from 2006-2019. Read More

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Microbiome of the Middle Meatus in HIV.

West Afr J Med 2020 Dec;37(7):801-804

Gombe State University and Federal Teaching Hospital, Gombe, Nigeria.

Background: Infection with Human Immunodeficiency Virus (HIV) leads to immune dysfunction with increased risk of developing varied infections including opportunistic infections. It may be that a change in the microbial community of HIV patients could be contributory to their development of rhinosinusitis. However, the normal sinonasal microbiome in HIV is yet to be thoroughly studied. Read More

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December 2020

Atypical Presentation of Periprosthetic Joint Infection After Total Knee Arthroplasty due to .

Arthroplast Today 2020 Dec 4;6(4):901-905. Epub 2020 Nov 4.

Department of Orthopaedic Surgery, Beaumont Health, Royal Oak, MI, USA.

There is limited literature reporting the oral pathogen as the causative organism of periprosthetic joint infection. Previous reports demonstrate septic arthritis in native or prosthetic joints due to in elderly or immunocompromised patients associated with tooth abscess and periodontal disease. Our case report is unique because it describes a healthy individual with recurrent gingivitis developing periprosthetic joint infection after total knee arthroplasty as the result of isolated . Read More

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December 2020

Changes in the diversity and composition of gut microbiota in pigeon squabs infected with Trichomonas gallinae.

Sci Rep 2020 11 17;10(1):19978. Epub 2020 Nov 17.

Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing, China.

Pigeons, as the only altricial birds in poultry, are the primary Trichomonas gallinae (T. gallinae) host. To study the effects of T. Read More

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November 2020

Fusobacterium nucleatum in biopsied tissues from colorectal cancer patients and alcohol consumption in Korea.

Sci Rep 2020 11 16;10(1):19915. Epub 2020 Nov 16.

Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

The roles of individual bacteria and their relationship in the development of colorectal cancer (CRC) remain unclear. We aimed to determine the prevalence of CRC-associated bacteria using quantitative real-time PCR (qPCR) or 16S rRNA analysis and the statistical correlations of patient demographics and clinical characteristics comprising alcohol consumption with CRC-associated bacteria. We determined the prevalence of five CRC-associated bacterial species in 38 CRC patients (39 samples) and 21 normal individuals using qPCR, and the relative abundance of bacterial taxa in the gut microbiome was assessed using 16S rRNA analysis. Read More

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November 2020

Pathogen identification in culture-negative cerebrospinal fluid specimens of patients with purulent meningitis using next-generation sequencing technology.

Int J Clin Exp Pathol 2020 1;13(9):2427-2438. Epub 2020 Sep 1.

College of Life Science, Northwest University 229 North Taibai Road, Xi'an 710069, Shaanxi, P. R. China.

Antimicrobial therapy necessitates fast and accurate detection of pathogens in purulent meningitis (PM) diagnosis. Although considered a gold standard, the traditional bacterial detection and identification methods based on routine bacterial culture are time-consuming and show low sensitivity and specificity. In order to reduce PM-related deaths and improve the treatment efficiency, we employed trace DNA extraction technology and combined it with Next-Generation Sequencing technology for bacteria identification. Read More

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September 2020

Evaluation of different culture media to support in vitro growth and biofilm formation of bacterial vaginosis-associated anaerobes.

PeerJ 2020 10;8:e9917. Epub 2020 Sep 10.

Laboratory of Research in Biofilms Rosário Oliveira-Centre of Biological Engineering, University of Minho, Braga, Portugal.

Background: Bacterial vaginosis (BV) is one of the most common vaginal infections worldwide. It is associated with the presence of a dense polymicrobial biofilm on the vaginal epithelium, formed mainly by species. The biofilm also contains other anaerobic species, but little is known about their role in BV development. Read More

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September 2020

Alterations in Gut Microbiome in Cirrhosis as Assessed by Quantitative Metagenomics: Relationship With Acute-on-Chronic Liver Failure and Prognosis.

Gastroenterology 2021 Jan 14;160(1):206-218.e13. Epub 2020 Sep 14.

Liver Unit, Hospital Clínic de Barcelona, Barcelona, Spain; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain; Centro de Investigacion en Red de Enfermedades Hepaticas y Digestivas (CIBEReHD), Madrid, Spain. Electronic address:

Background And Aims: Cirrhosis is associated with changes in gut microbiome composition. Although acute-on-chronic liver failure (ACLF) is the most severe clinical stage of cirrhosis, there is lack of information about gut microbiome alterations in ACLF using quantitative metagenomics. We investigated the gut microbiome in patients with cirrhosis encompassing the whole spectrum of disease (compensated, acutely decompensated without ACLF, and ACLF). Read More

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January 2021

Subgingival microflora in adolescent females with polycystic ovary syndrome and its association with oral hygiene, gingivitis, and selected metabolic and hormonal parameters.

Clin Oral Investig 2021 Mar 10;25(3):1485-1496. Epub 2020 Aug 10.

Department of Perinatology and Gynecology, Division of Developmental Gynecology and Sexology, Poznan University of Medical Sciences, 22 Polna Street, 60-535, Poznan, Poland.

Objectives: Research studies suggest that polycystic ovary syndrome (PCOS) may influence the composition of the oral microflora in women. This study aimed to investigate factors affecting the number of selected periopathogens in a young cohort of females with PCOS and to assess the association between oral hygiene, subgingival microbiome, gingival health, and metabolic and hormonal parameters.

Materials And Methods: Thirty-two subjects with PCOS and twenty-three healthy controls aged 15-19 years were examined periodontally by a calibrated dentist. Read More

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The canine skin and ear microbiome: A comprehensive survey of pathogens implicated in canine skin and ear infections using a novel next-generation-sequencing-based assay.

Vet Microbiol 2020 Aug 17;247:108764. Epub 2020 Jun 17.

MiDOG LLC, 17062 Murphy Ave, Irvine, CA, 92614, USA; Zymo Research Corporation, 17062 Murphy Ave, Irvine, CA, 92614, USA. Electronic address:

This study analyzed the complex bacterial and fungal microbiota of healthy and clinically affected canine ear and skin samples. A total of 589 canine samples were included: 257 ear swab samples (128 healthy vs. 129 clinically affected) and 332 skin swab samples (172 healthy vs. Read More

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[Antimicrobial Susceptibility of Pathogenic Gram-positive Anaerobic Cocci: Data of a University Hospital in Turkey].

Mikrobiyol Bul 2020 Jul;54(3):404-417

Marmara University Faculty of Medicine, Department of Medical Microbiology, Istanbul, Turkey.

Gram-positive anaerobic cocci (GPAC), a large group of anaerobic bacteria, are the members of the normal microbiota that colonizes the skin and mucosal surfaces of the human body. However, in case of a wound or when the host becomes immunocompromised, GPAC can cause invasive and most frequently mixed infections. GPAC are the second most frequently isolated bacteria in anaerobic infections. Read More

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Antimicrobial susceptibility patterns of anaerobic bacteria identified from clinical specimens of diseased dogs and cats.

J Vet Med Sci 2020 Oct 27;82(9):1316-1320. Epub 2020 Jul 27.

Laboratory of Infectious Diseases, Graduate School of Infection Control Sciences & Ōmura Satoshi Memorial Institute, Kitasato University, Shirokane, Minato-ku, Tokyo 108-8641, Japan.

We aimed to clarify antimicrobial susceptibility patterns of anaerobes from diseased companion animals. Bacterial identification was based on the Japanese 2012 guidelines for the testing of anaerobic bacteria. AST was performed using the broth microdilution method. Read More

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October 2020

An Unusual Presentation of Prostatic Abscess due to Actinomyces turicensis and Peptostreptococcus.

Cureus 2020 Jun 17;12(6):e8665. Epub 2020 Jun 17.

Infectious Diseases, State University of New York Downstate Medical Center, Brooklyn, USA.

Actinomyces is a rare cause of prostatic abscess. Most reported cases of abdominal and pelvic actinomycosis are a consequence of invasive procedures or abdominal infections. In this report, we present a previously healthy 53-year-old man with inguinal pain, fever and dysuria who was found to have a prostate abscess, secondary to Actinomyces turicensis and Peptostreptococcus, which was removed via transurethral resection of the prostate. Read More

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The NF-κB Signaling Pathway, the Microbiota, and Gastrointestinal Tumorigenesis: Recent Advances.

Front Immunol 2020 30;11:1387. Epub 2020 Jun 30.

Department of Gastroenterology, The First Affiliated Hospital of Nanchang University, Nanchang, China.

Gastrointestinal (GI) cancers, especially gastric cancer and colorectal cancer (CRC), represent a major global health burden. A large population of microorganisms residing in the GI tract regulate physiological processes, such as the immune response, metabolic balance, and homeostasis. Accumulating evidence has revealed the alteration of microbial communities in GI tumorigenesis. Read More

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The Alterations of Vaginal Microbiome in HPV16 Infection as Identified by Shotgun Metagenomic Sequencing.

Front Cell Infect Microbiol 2020 23;10:286. Epub 2020 Jun 23.

Women's Reproductive Health Laboratory of Zhejiang Province, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

The association of microbiome imbalance with cancer development is being one of the research hotspots. Persistent HPV infection is a causal event in cervical cancer initiation, but, little is known about the microbiome composition and function in HPV infection. Here we identified the compositional and functional alterations on vaginal samples from 27 HPV16 positive women and 25 age-matched HPV negative controls using shotgun metagenomic sequencing, to provide a comprehensive investigation describing the microbial abundances and enriched metabolic functions in cervicovaginal metagenomes. Read More

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Gallstone Disease and Microbiome.

Microorganisms 2020 Jun 2;8(6). Epub 2020 Jun 2.

Laboratory of Gastroenterology, Research Institute of Internal and Preventive Medicine-Branch of The Federal Research Center Institute of Cytology and Genetics of Siberian Branch of Russian Academy of Sciences, Novosibirsk 630089, Russia.

Gallstone disease (GSD) has, for many years, remained a high-cost, socially significant public health problem. Over the past decade, a number of studies have been carried out-both in humans and in animal models-confirming the role of the microbiota in various sections of the gastrointestinal tract as a new link in the etiopathogenesis of GSD. The microbiome of bile correlates with the bacterial composition of saliva, and the microbiome of the biliary tract has a high similarity with the microbiota of the duodenum. Read More

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: a rare cause of necrotising fasciitis.

BMJ Case Rep 2020 May 27;13(5). Epub 2020 May 27.

General Surgery, North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK.

Necrotising fasciitis is a life-threatening condition characterised by inflammation, affecting the soft tissues, which spreads within a fascial plane. Skin changes can be delayed and can often go unnoticed. The condition arises from a bacterial infection, commonly being of polymicrobial aetiology. Read More

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Clinical Utility of Anaerobic and Fungal Blood Cultures in the Pediatric Oncologic Population.

J Pediatr Hematol Oncol 2020 07;42(5):345-349

Department of Pediatrics, School of Medicine and Health Sciences, Division of Infectious of Diseases, Children's National Health System, The George Washington University, Washington, DC.

Background: If there is a concern for sepsis in a pediatric patient an aerobic blood culture is obtained. A febrile or ill oncology patient will often be evaluated with aerobic, anaerobic, and fungal blood cultures. There is to our knowledge little evidence to confirm the added benefit of broadly obtaining these cultures. Read More

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A Tale of Two Loculations.

Ann Am Thorac Soc 2020 04;17(4):517-519

Department of Emergency Medicine, McGaw Medical Center of Northwestern University, Chicago, Illinois.

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Association of oral dysbiosis with oral cancer development.

Oncol Lett 2020 Apr 3;19(4):3045-3058. Epub 2020 Mar 3.

Department of Biomedical and Biotechnological Sciences, University of Catania, I-95123 Catania, Italy.

Oral squamous cell carcinoma (OSCC) is the leading cause of mortality for oral cancer. Numerous risk factors mainly related to unhealthy habits and responsible for chronic inflammation and infections have been recognized as predisposing factors for oral carcinogenesis. Recently, even microbiota alterations have been associated with the development of human cancers. Read More

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[Virusuria as a component of the urine microbiota and its significance for assessing the health of the urinary tract: a descriptive clinical study].

Urologiia 2020 Mar(1):12-18

Rostov State Medical University, Rostov-on-Don, Russia.

Aim: To determine the frequency of occurrence of oportunistic pathogenic bacterial flora and viral pathogens in the urine of healthy people with the establishment of the association between them.

Materials And Methods: 40 healthy sexually active women and men were examined, which are divided by gender into equivalent groups: Group I - healthy women (n=19), Group II - healthy men (n=21). The age of the subjects ranged from 20 to 25 years, the average age was 22. Read More

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