1,511 results match your criteria Peptostreptococcus Infection


: a rare cause of necrotising fasciitis.

BMJ Case Rep 2020 May 27;13(5). Epub 2020 May 27.

General Surgery, North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK.

Necrotising fasciitis is a life-threatening condition characterised by inflammation, affecting the soft tissues, which spreads within a fascial plane. Skin changes can be delayed and can often go unnoticed. The condition arises from a bacterial infection, commonly being of polymicrobial aetiology. Read More

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http://dx.doi.org/10.1136/bcr-2020-235115DOI Listing

Association of oral dysbiosis with oral cancer development.

Oncol Lett 2020 Apr 3;19(4):3045-3058. Epub 2020 Mar 3.

Department of Biomedical and Biotechnological Sciences, University of Catania, I-95123 Catania, Italy.

Oral squamous cell carcinoma (OSCC) is the leading cause of mortality for oral cancer. Numerous risk factors mainly related to unhealthy habits and responsible for chronic inflammation and infections have been recognized as predisposing factors for oral carcinogenesis. Recently, even microbiota alterations have been associated with the development of human cancers. Read More

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http://dx.doi.org/10.3892/ol.2020.11441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079586PMC

[Virusuria as a component of the urine microbiota and its significance for assessing the health of the urinary tract: a descriptive clinical study].

Urologiia 2020 Mar(1):12-18

Rostov State Medical University, Rostov-on-Don, Russia.

Aim: To determine the frequency of occurrence of oportunistic pathogenic bacterial flora and viral pathogens in the urine of healthy people with the establishment of the association between them.

Materials And Methods: 40 healthy sexually active women and men were examined, which are divided by gender into equivalent groups: Group I - healthy women (n=19), Group II - healthy men (n=21). The age of the subjects ranged from 20 to 25 years, the average age was 22. Read More

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[Evaluation of the composition of the microbiota of the urethra in men with sexually transmitted infections].

Urologiia 2019 12(6):31-37

State Research Center Institute of immunology of Federal Medical Biological Agency, Moscow, Russia.

Objective: to conduct a comparative study of the composition of the microbiota of the urethra in men with sexually transmitted infections (STIs), and healthy men.

Material And Methods: The study included 103 men aged 18 to 45 years: 42 men with urethritis caused by STIs and 61 clinically healthy men. Identification of pathogenic and conditionally pathogenic microorganisms in scrapings from the urethra was performed by PCR in real time (test system Androflor (DNA-Technology, Moscow). Read More

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December 2019

Treating an intramuscular abscess following toothpick injury in a diabetic patient: A case report and literature review (CARE Complaint).

Medicine (Baltimore) 2019 Nov;98(48):e18159

Department of Emergency Medicine, Taichung Veterans General Hospital.

Rationale: Toothpick puncture (TPP) is a penetrating injury that can result in bringing pathogens to the deep space. Such penetrating wounds are typically of pinpoint size with initial symptoms appearing subtle. Consequently, the injury itself is often neglected by patients, or is not detected during physical examinations by medical doctors. Read More

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http://dx.doi.org/10.1097/MD.0000000000018159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6890348PMC
November 2019

Evidence that intra-amniotic infections are often the result of an ascending invasion - a molecular microbiological study.

J Perinat Med 2019 Nov;47(9):915-931

Perinatology Research Branch, Division of Obstetrics and Maternal-Fetal Medicine, Division of Intramural Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, MD and Detroit, MI, USA.

Background Microbial invasion of the amniotic cavity resulting in intra-amniotic infection is associated with obstetrical complications such as preterm labor with intact or ruptured membranes, cervical insufficiency, as well as clinical and histological chorioamnionitis. The most widely accepted pathway for intra-amniotic infection is the ascension of microorganisms from the lower genital tract. However, hematogenous dissemination of microorganisms from the oral cavity or intestine, retrograde seeding from the peritoneal cavity through the fallopian tubes, and introduction through invasive medical procedures have also been suggested as potential pathways for intra-amniotic infection. Read More

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http://dx.doi.org/10.1515/jpm-2019-0297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147941PMC
November 2019
1 Read
1.425 Impact Factor

Rectal Microbiota Associated With and Infections in Men Having Sex With Other Men.

Front Cell Infect Microbiol 2019 18;9:358. Epub 2019 Oct 18.

National Research Council, Institute of Biomedical Technologies, Milan, Italy.

(CT) and (NG) represent the most common agents of sexually transmitted rectal infections among men having sex with other men (MSM). In this study, we assessed the bacterial composition of the rectal microbiota associated with CT and/or NG infections in a cohort of men reporting unsafe rectal intercourse. A total of 125 rectal swabs were collected and four groups were compared: non-infected subjects ( = 53), patients with CT ( = 37), or NG rectal infection ( = 17) and patients with contemporary positivity for CT/NG ( = 18). Read More

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http://dx.doi.org/10.3389/fcimb.2019.00358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813206PMC
October 2019

Changes in Microbiota and Development of Nonspecific Inflammation of Genitals in Female C57Bl/6 Mice after Aerosol Infection with Mycobacterium tuberculosis.

Bull Exp Biol Med 2019 Sep 17;167(5):645-649. Epub 2019 Oct 17.

Central Research Institute for Tuberculosis, Moscow, Russia.

Infectious process even at the initial stage after aerosol infection with Mycobacterium tuberculosis induced rapid changes in vaginal microbiota in mice. Rapid decrease in both the quantity and diversity of microbiota was noted, and then, partial recovery of normal flora was observed. Changes in vaginal microbiota was detected as soon as in 3-7 days after lung infection, while inflammatory changes appeared by day 35. Read More

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http://dx.doi.org/10.1007/s10517-019-04589-8DOI Listing
September 2019

The Factors Contributing to Efficiency in Surgical Management of Purulent Infections of Deep Neck Spaces.

Ear Nose Throat J 2019 Sep 29:145561319877281. Epub 2019 Sep 29.

Otolaryngology Department, Medical University of Warsaw, Warszawa, Poland.

Deep neck infections (DNIs) are still emergency conditions in otorhinolaryngology. Due to rapid disease progression and life-threatening complications, the accurate surgical and medical treatment must be promptly applied. In the present study, we analyzed treatment protocols of 46 adults to assess efficacy of the treatment and search for prognostic factors of the outcomes. Read More

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http://dx.doi.org/10.1177/0145561319877281DOI Listing
September 2019

Vaginal microbiota and human papillomavirus: a systematic review

J Turk Ger Gynecol Assoc 2019 Sep 30. Epub 2019 Sep 30.

First Department of Dermatology and Venereology, National and Kapodistrian University of Athens School of Medicine "A. Syggros" Hospital for Skin and Venereal Diseases, Athens, Greece

Background: Accumulating evidence indicates the potential correlation between the vaginal microbioma and the acquisition and persistence of Human Papillomavirus (HPV) infection. This study has as intention to demonstrate the potential relationship through a systematic review of the current literature.

Methods: A search was conducted on the following medical databases: PubMed and Scopus. Read More

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http://dx.doi.org/10.4274/jtgga.galenos.2019.2019.0051DOI Listing
September 2019
2 Reads

Bacteriological Profile of Aerobic and Anaerobic Isolates of Trophic Ulcer in Leprosy: A Study from Eastern India.

Indian J Dermatol 2019 Sep-Oct;64(5):372-376

Department of Dermatology, STM, Kolkata, West Bengal, India.

Introduction: Trophic ulcer is a dreaded complication of leprosy. Secondary infection compounds the damage to the already neglected ulcer.

Aims: To find out the bacterial pathogens in the isolates from trophic ulcers of leprosy and to find the drug sensitivity of the aerobic isolates so as to start a suitable antibiotic therapy. Read More

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http://dx.doi.org/10.4103/ijd.IJD_310_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749753PMC
September 2019
2 Reads

Microbiome on the Bone-Anchored Hearing System: A Prospective Study.

Front Microbiol 2019 26;10:799. Epub 2019 Apr 26.

IS-Diagnostics Ltd., Amsterdam, Netherlands.

The bone-anchored hearing system (BAHS) has evolved to a common treatment option for various types of hearing revalidation. The BAHS consists of an implant in the skull that breeches the skin. Soft tissue reactions are a common complication associated with BAHS and are generally poorly understood. Read More

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http://dx.doi.org/10.3389/fmicb.2019.00799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498861PMC
April 2019
5 Reads

The Gut Microbiota-Host Partnership as a Potential Driver of Kawasaki Syndrome.

Front Pediatr 2019 5;7:124. Epub 2019 Apr 5.

Institute of Pediatrics, IRCCS, Rome, Italy.

Kawasaki syndrome (KS) is a necrotizing vasculitis of small- and medium-sized vessels mostly affecting children under 5 years of age; a host of clinical and epidemiological data supports the notion that KS might result from an infectious disease. However, many efforts have failed to identify a potentially universal trigger of KS. The contribution of the intestinal microbial community-called the "microbiota"-to KS has been evaluated by an increasing number of studies, though limited to small cohorts of patients. Read More

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https://www.frontiersin.org/article/10.3389/fped.2019.00124/
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http://dx.doi.org/10.3389/fped.2019.00124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460951PMC
April 2019
13 Reads

Antimicrobial susceptibilities of clinical isolates of the anaerobic bacteria which can cause aspiration pneumonia.

Anaerobe 2019 Jun 2;57:86-89. Epub 2019 Apr 2.

Department of Infection Control and Prevention, Aichi Medical University Hospital, Aichi, Japan; Department of Clinical Infectious Diseases, Aichi Medical University Graduate School of Medicine, Aichi, Japan. Electronic address:

Aspiration pneumonia is an infectious disease of the lungs caused by inhalation of saliva or foods, associated with swallowing dysfunction. Therefore, the major causative organisms are oral or gastric bacteria. In this study, we evaluated the antimicrobial susceptibility patterns of the anaerobic bacteria which can cause aspiration pneumonia, Fusobacterium spp. Read More

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http://dx.doi.org/10.1016/j.anaerobe.2019.04.002DOI Listing
June 2019
9 Reads

Prevalence of cases of amebic liver abscess in a tertiary care centre in India: A study on risk factors, associated microflora and strain variation of Entamoeba histolytica.

PLoS One 2019 3;14(4):e0214880. Epub 2019 Apr 3.

Department of Gastroenterology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, U.P., India.

Background: Amebiasis, caused by Entamoeba histolytica (E. histolytica), is a significant cause of morbidity and mortality in developing countries. Mortality due to amebiasis is mostly by extra intestinal infections, amebic liver abscess being the most common one. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214880PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447230PMC
December 2019
26 Reads

Sonication of Extracted Implants Improves Microbial Detection in Patients With Orthopedic Implant-Associated Infections.

J Arthroplasty 2019 06 20;34(6):1189-1196. Epub 2019 Feb 20.

Department of Orthopedic Surgery, Kansai Medical University, Hirakata, Osaka, Japan.

Background: We assessed whether combining the conventional culture and implant sonicate fluid culture (SFC) methods increased the diagnostic accuracy of orthopedic implant-associated infection (OIAI).

Methods: Consecutive patients (n = 66) undergoing implant removal (OIAI, 17; non-OIAI, 49) were evaluated prospectively. We analyzed 493 samples (39 preoperative joint aspirates, 243 peri-implant tissue specimens, 124 implant sonication, 67 controls, and 20 water bath samples). Read More

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http://dx.doi.org/10.1016/j.arth.2019.02.020DOI Listing
June 2019
4 Reads

Potential risk factors and outcomes of infection with multidrug resistance among diabetic patients having ulcers: 7 years study.

Diabetes Metab Syndr 2019 Jan - Feb;13(1):414-418. Epub 2018 Oct 13.

Former Professor of Endocrinology and Dean, Faculty of Medicine, Ex-Director, Rajiv Gandhi Centre for Diabetes and Endocrinology, Former Dean, Faculty of Medicine, J.N. Medical College, Aligarh Muslim University, Aligarh, 202002, India; Consultant, Diabetes and Superspeciality Center, Central Tower Ground Floor, Kela Nagar Chauraha, Aligarh, 202002, India.

Diabetes Mellitus is characterized as a hyperglycemic condition, which results due to alteration in the secretion of insulin or action of insulin. The development and spread of microorganisms is known as a key health concern, and such cases are growing drastically in hospitals and communities. Therefore, the study aims to determine the potential risk factors and infection outcomes among diabetic patients with multi drug resistance, who are suffering from foot ulcerations. Read More

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http://dx.doi.org/10.1016/j.dsx.2018.10.014DOI Listing
May 2019
6 Reads

A Case Report of Vertebral Osteomyelitis Caused by Peptostreptococcus micros.

J Orthop Case Rep 2018 May-Jun;8(3):7-9

Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.

Introduction: Anaerobic vertebral osteomyelitis has been reported rarely. In this report, we describe an extremely rare case of a patient who suffered from vertebral osteomyelitis caused by Peptostreptococcus micros.

Case Report: A 73-year-old man with a history of diabetes mellitus was admitted to our hospital with a 5-month history of severe low back pain. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298707PMC
December 2018
9 Reads

Necrotizing Myositis: A Rare Necrotizing Soft Tissue Infection Involving Muscle.

Wounds 2018 Dec;30(12):E116-E120

Department of Surgery, NYU Winthrop Hospital, Mineola, NY.

Introduction: Necrotizing myositis (NM) is an extremely rare necrotizing soft tissue infection involving muscle. Unlike similar infections (eg, necrotizing fasciitis, clostridial myonecrosis) that can be more readily diagnosed, NM can have a benign presentation then rapidly progress into a life-threatening condition with a mortality rate of 100% without surgical intervention.

Case Report: A 74-year-old man with a history of prostate cancer with radiation therapy, seed implants, and 2 transurethral resection procedures presented to the emergency department after a fall. Read More

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December 2018
46 Reads

An Unusual Presentation of Parvimonas micra Infective Endocarditis.

Cureus 2018 Oct 13;10(10):e3447. Epub 2018 Oct 13.

Internal Medicine, Woodlands Health Care, Singapore, SGP.

Parvimonas micra has been identified as a prominent oral pathogen. This organism has been implicated in periodontal, soft tissue and bone infections. It causes a subacute presentation with high morbidity. Read More

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https://www.cureus.com/articles/14643-an-unusual-presentatio
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http://dx.doi.org/10.7759/cureus.3447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294278PMC
October 2018
9 Reads

Complicated Necrotizing Otitis Externa Progressing to Coalescent Mastoiditis and Temporal Lobe Abscess.

Am J Med 2019 02 25;132(2):e39-e40. Epub 2018 Oct 25.

Department of Pulmonary, Critical Care and Sleep Medicine, MedStar Georgetown University Hospital, Washington, DC.

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http://dx.doi.org/10.1016/j.amjmed.2018.10.005DOI Listing
February 2019
9 Reads

Clinical and microbiological features of bacteraemia with Gram-positive anaerobic cocci: a population-based retrospective study.

Clin Microbiol Infect 2019 Jun 11;25(6):760.e1-760.e6. Epub 2018 Sep 11.

Lund University, Faculty of Medicine, Department of Clinical Sciences, Division of Infection Medicine, Lund, Sweden; Skåne University Hospital, Division of Infection Medicine, Lund, Sweden. Electronic address:

Objectives: Gram-positive, anaerobic cocci (GPAC) can cause infections in humans. Only a few cases of bacteraemia with GPAC have been reported. We describe the clinical and microbiological characteristics of GPAC bacteraemia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1198743X183062
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http://dx.doi.org/10.1016/j.cmi.2018.09.001DOI Listing
June 2019
52 Reads

Parvimonas micra bacteremia following endoscopic retrograde cholangiopancreatography: A new route of infection.

Anaerobe 2018 Dec 11;54:136-139. Epub 2018 Sep 11.

Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy.

Parvimonas micra is an anaerobic, Gram-positive coccus belonging to oral, gastrointestinal and genital flora, rarely causing infections in humans. It was mainly deemed to cause bacteremia, septic bone and cerebral infections in patients which have undergone dental procedures or with suboptimal dental hygiene. We report the first case of Parvimonas micra bacteremia following endoscopic retrograde colangiopancreatography performed due to choledocholithiasis in a patient with good oral health. Read More

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http://dx.doi.org/10.1016/j.anaerobe.2018.09.003DOI Listing
December 2018
19 Reads

Brain abscesses in a 60-year-old man.

Cleve Clin J Med 2018 09;85(9):672-674

Department of Medicine, Kettering Medical Center, Kettering, OH, USA.

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http://dx.doi.org/10.3949/ccjm.85a.17130DOI Listing
September 2018
3 Reads

A Retrospective Analysis of Anaerobic Bacteria Isolated in 236 Cases of Pleural Empyema and their Prevalance of Antimicrobial Resistance in Turkey.

Clin Lab 2018 Jul;64(7):1269-1277

Background: Parapneumonic effusions usually occur secondary to an infection and produce pus (empyema) that accumulates in the pleural space. We aimed to evaluate the prevalence of anerobes in patients with empyema and to assess their resistance patterns for seven antimicrobials.

Methods: Pleural fluid specimens from 236 patients were inoculated on Schaedler agar. Read More

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http://dx.doi.org/10.7754/Clin.Lab.2018.180317DOI Listing
July 2018
48 Reads

Clostridium difficile and Clostridioides difficile: Two validly published and correct names.

Anaerobe 2018 Aug 20;52:125-126. Epub 2018 Jul 20.

National Laboratory for Health, Environment and Food, NLZOH, Maribor, Slovenia; University of Maribor, Faculty of Medicine, Maribor, Slovenia. Electronic address:

The current status of the names Clostridium difficile and Clostridioides difficile is explained in view of the current confusion about the correct name of this well-known pathogen. Both names have been validly published under the provisions of the Prokaryotic Code and both names can be used. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10759964183012
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http://dx.doi.org/10.1016/j.anaerobe.2018.07.005DOI Listing
August 2018
8 Reads

HPV infection and bacterial microbiota in the placenta, uterine cervix and oral mucosa.

Sci Rep 2018 06 28;8(1):9787. Epub 2018 Jun 28.

Department of Oral Pathology and Oral Radiology, Institute of Dentistry, Faculty of Medicine, University of Turku, Turku, Finland.

We investigated the association between HPV infection and bacterial microbiota composition in the placenta, uterine cervix and mouth in thirty-nine women. HPV DNA genotyping of 24 types was conducted using Multimetrix. Microbiota composition was characterized by 16S rRNA gene sequencing. Read More

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http://dx.doi.org/10.1038/s41598-018-27980-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6023934PMC
June 2018
5 Reads

Peptostreptococcus canis and Bacteroides pyogenes prosthetic joint infection.

Enferm Infecc Microbiol Clin 2019 May 9;37(5):347-348. Epub 2018 Jun 9.

Unidad de Gestión Clínica de Enfermedades Infecciosas y Microbiología, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen Macarena/Universidad de Sevilla/Centro Superior de Investigaciones Científicas (CSIC), Sevilla, España.

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https://linkinghub.elsevier.com/retrieve/pii/S0213005X183019
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http://dx.doi.org/10.1016/j.eimc.2018.05.004DOI Listing
May 2019
4 Reads

Nasal septal abscess caused by anaerobic bacteria of oral flora.

Auris Nasus Larynx 2019 Feb 7;46(1):147-150. Epub 2018 Jun 7.

Department of Otolaryngology, Kawasaki Medical School, Kurashiki, Japan. Electronic address:

Although nasal septal abscess (NSA) was formerly common, it has become rare since the development of antibiotics. NSA, if left untreated, can lead to intracranial complications such as meningitis and eventually result in saddle-nose deformity. NSA often occurs after injury, and indigenous skin bacteria such as Staphylococcus aureus are frequently detected. Read More

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http://dx.doi.org/10.1016/j.anl.2018.05.014DOI Listing
February 2019
13 Reads

Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer.

Gastroenterology 2018 08 3;155(2):383-390.e8. Epub 2018 May 3.

State Key Laboratory of Digestive Disease, Institute of Digestive Disease, Li Ka Shing Institute of Health Sciences, and CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong. Electronic address:

Background & Aims: Colorectal cancer (CRC) development has been associated with increased proportions of Bacteroides fragilis and certain Streptococcus, Fusobacterium, and Peptostreptococcus species in the intestinal microbiota. We investigated associations between bacteremia from specific intestinal microbes and occurrence of CRC.

Methods: We performed a retrospective study after collecting data on 13,096 adult patients (exposed group) in Hong Kong hospitalized with bacteremia (identified by blood culture test) without a previous diagnosis of cancer from January 1, 2006 through December 31, 2015. Read More

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http://dx.doi.org/10.1053/j.gastro.2018.04.028DOI Listing
August 2018
24 Reads

Bacterial diversity in the feces of dogs with CPV infection.

Microb Pathog 2018 Aug 27;121:70-76. Epub 2018 Apr 27.

College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou, Guangdong Province, 510642, People's Republic of China. Electronic address:

Canine parvovirus (CPV) is a contagious disease in dogs that has high morbidity and mortality. In cases of infection, the pups tend to have a higher mortality and more severe clinical symptoms than the adult dogs because the dehydration is difficult for pups to bear. Following the natural infection, there is a rapid antibody response neutralizing the extracellular virus. Read More

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http://dx.doi.org/10.1016/j.micpath.2018.04.043DOI Listing
August 2018
6 Reads

Ageing with HIV - a periodontal perspective.

New Microbiol 2018 Jan;41(1):61-66

School of Dental Medicine, University of Belgrade, Serbia.

The importance of oral microflora composition in HIV-infected patients is well recognized. However, no studies so far have dealt with age-related changes in periodontal pathogens occurrence in HIV+ individuals. The aim of the present study was to assess and compare temporal changes of bacteria frequency in younger (≤35 years) and older (≥50 years) HIV-infected and non-infected individuals. Read More

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January 2018
41 Reads

Activities of Omadacycline and Comparators against Anaerobic Bacteria.

Antimicrob Agents Chemother 2018 04 27;62(4). Epub 2018 Mar 27.

Micromyx, Inc., Kalamazoo, Michigan, USA.

Omadacycline (OMC), a broad-spectrum aminomethylcycline, has shown clinical efficacy in anaerobic acute bacterial skin and skin structure infections (ABSSSI) and in animal models of intra-abdominal anaerobic infections. Here, the activity of OMC against clinically relevant anaerobes was similar to that of tigecycline, with MIC values of 1 to 8 μg/ml against spp., 0. Read More

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http://dx.doi.org/10.1128/AAC.00047-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5913939PMC
April 2018
4 Reads

Teenage boy with high fever and rash: what could we be missing?

BMJ Case Rep 2018 Feb 8;2018. Epub 2018 Feb 8.

Paediatric Intensive Care Unit, Hospital Pediátrico de Coimbra, Coimbra, Portugal.

A 15-year-old boy was admitted to a local hospital with high fever, generalised rash and a mild sore throat. He was started on intravenous flucloxacillin and 12 hours later develops a sustained low diastolic blood pressure (DBP), unresponsive to fluid volume expansion and cardiovascular support with dopamine. Intravenous clindamycin was added and transportation to paediatric intensive care unit arranged. Read More

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http://dx.doi.org/10.1136/bcr-2017-223497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836690PMC
February 2018
15 Reads

Anaerobic bacterial meningitis in adults.

J Clin Neurosci 2018 Apr 1;50:45-50. Epub 2018 Feb 1.

Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address:

Anaerobic infection is a very uncommon condition in adult bacterial meningitis (ABM), and its clinical characteristics have yet to be clarified. We enrolled 540 patients with culture-proven bacterial meningitis during a study period of 30 years (1986-2015), of whom 13 (2.4%) had anaerobic infections. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868173188
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http://dx.doi.org/10.1016/j.jocn.2018.01.014DOI Listing
April 2018
28 Reads

Fournier's Gangrene: Clinical Presentation of 13 Cases.

Med Sci Monit 2018 Jan 28;24:548-555. Epub 2018 Jan 28.

Department of General, Oncological and Functional Urology, Medical University of Warsaw, Warsaw, Poland.

BACKGROUND Fournier's gangrene (FG) is a fulminant form of infective, polymicrobial, necrotizing fasciitis of the perineal, genital, and perianal regions. It commonly affects men, but women and children may also develop this type of tissue necrosis. MATERIAL AND METHODS This study is a retrospective analysis of the management of 13 cases of Fournier's gangrene, diagnosed from among about 45 000 patients (men, women, and children) treated in the Department of General, Oncological, and Functional Urology (Medical University of Warsaw) from 1995 to 2013. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798415PMC
http://dx.doi.org/10.12659/msm.905836DOI Listing
January 2018
18 Reads

Risk of Infection After Allograft Anterior Cruciate Ligament Reconstruction: Are Nonprocessed Allografts More Likely to Get Infected? A Cohort Study of Over 10,000 Allografts.

Am J Sports Med 2018 Mar 3;46(4):846-851. Epub 2018 Jan 3.

Department of Orthopaedics, Southern California Permanente Medical Group, Baldwin Park, California, USA.

Background: Allograft tissue is frequently used in anterior cruciate ligament reconstruction (ACLR). It is often irradiated and/or chemically processed to decrease the risk of disease transmission, but some tissue is aseptically harvested without further processing. Irradiated and chemically processed allograft tissue appears to have a higher risk of revision, but whether this processing decreases the risk of infection is not clear. Read More

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http://dx.doi.org/10.1177/0363546517745876DOI Listing
March 2018
15 Reads

The oral microbiome-the relevant reservoir for acute pediatric appendicitis?

Int J Colorectal Dis 2018 Feb 22;33(2):209-218. Epub 2017 Dec 22.

Department of Pediatric Surgery, University of Leipzig, Liebigstr. 20A, 04103, Leipzig, Germany.

Purpose: The oral microbiome has been related to numerous extra oral diseases. Recent studies detected a high abundance of oral bacteria in inflamed appendices in pediatric patients. To elucidate the role of oral bacteria in acute pediatric appendicitis, we studied the oral and appendiceal microbiome of affected children compared to healthy controls. Read More

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http://dx.doi.org/10.1007/s00384-017-2948-8DOI Listing
February 2018
20 Reads

Subdural empyema caused by Peptostreptococcus sp.: a complication of acute pharyngitis.

Rev Inst Med Trop Sao Paulo 2017 Dec 21;59:e83. Epub 2017 Dec 21.

Tulane University, School of Public Health and Tropical Medicine, New Orleans, United States.

Subdural Empyema (ESD) is the collection of purulent fluid that develops between the exterior "dura mater" layer and the middle "arachnoid mater" layer that covers the brain. ESD can be caused by a primary infection located in the paranasal sinuses. In many aerobic and/or anaerobic bacterial cases, hearing or traumatic processes serve as the causative agent. Read More

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http://dx.doi.org/10.1590/S1678-9946201759083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5738768PMC
December 2017
18 Reads

Human Infection with without Jugular Venous Thrombosis: A Varied Presentation of Lemierre's Syndrome.

Case Rep Infect Dis 2017 24;2017:5358095. Epub 2017 Oct 24.

Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.

Lemierre's syndrome is also known as postangina septicemia, which is commonly caused by also known as Necrobacillus and also by other microorganisms like , , , and . Though the disease starts as an upper respiratory tract infection, it may spread and cause thrombophlebitis of the internal jugular vein. It may present itself through cranial nerve palsy or sepsis involving distant organs like the lungs or bones. Read More

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http://dx.doi.org/10.1155/2017/5358095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674496PMC
October 2017
25 Reads

[Pathogen analysis in patients with diabetic foot osteomyelitis using 16S rRNA high-throughput sequencing].

Nan Fang Yi Ke Da Xue Xue Bao 2017 Nov;37(11):1448-1455

Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. E-mail:

Objective: To analyze the characteristics of pathogenic microorganisms in the infected bone tissues in patients with diabetic foot osteomyelitis (DFO) using 16S rRNA high-throughput sequencing to facilitate rapid and accurate detection of pathogens and effective infection control.

Methods: Between September, 2016 and April, 2017, 16 patients with DFO were admitted in our department and infected bone specimens were obtained during debridement. The pathogenic microorganisms in the specimens were identified using both 16S rRNA high-throughput sequencing and automatic blood culture analyzer, and the characteristics of the microflora were analyzed based on 16S rRNA sequencing data in comparison with the results of blood culture. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6779638PMC
November 2017
41 Reads

Fusobacterium emphysematous pyomyositis with necrotizing fasciitis of the leg presenting as compartment syndrome: a case report.

J Med Case Rep 2017 Nov 28;11(1):332. Epub 2017 Nov 28.

Department of Surgery, University of Illinois at Chicago, Chicago, 60612, IL, USA.

Background: Fusobacterium necrophorum is a common agent of disease in humans, but the occurrence of primary infections outside the head and neck area is extremely rare. While infection with Fusobacterium necrophorum has a rather benign course above the thorax, the organism is capable of producing very severe disease when located in unusual sites, including various forms of septic thrombophlebitis. No infections of the leg have been documented before; thus, antibiotic coverage for Fusobacterium is currently not recommended in this area. Read More

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http://dx.doi.org/10.1186/s13256-017-1493-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704428PMC
November 2017
31 Reads

Pyogenic Brain Abscess Caused by Peptostreptococcus in a Patient with HIV-1 Infection.

Diseases 2017 Nov 17;5(4). Epub 2017 Nov 17.

Gilead Sciences, Miami, FL 33136, USA.

In the setting of HIV, cerebral lesions are usually secondary to lymphoma and opportunistic infections; however, in patients with CD4 counts above 200 cells/uL, other pathologies such as pyogenic brain abscess could gain importance. The microbiology of pyogenic brain abscess has and as the leading etiologic pathogens in immunocompetent individuals. is also recognized as a common cause of brain abscess in this patient population. Read More

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http://dx.doi.org/10.3390/diseases5040026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750537PMC
November 2017
7 Reads

Septic arthritis of knee joint due to micra.

BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.

Internal Medicine, Section of Infectious Diseases, University of Illinois College of Medicine at Peoria, Peoria, Illinois, USA.

species are anaerobic, Gram-positive cocci that are a constituent of normal oral and gastrointestinal flora. We present a case of right knee joint septic arthritis due to in an immunocompromised patient. A 61-year-old male renal and pancreatic transplant recipient on immunosuppressive therapy was admitted to our hospital due to intense pain, joint swelling and inability to move his right knee over the past 9 months. Read More

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http://dx.doi.org/10.1136/bcr-2017-221926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695528PMC
November 2017
18 Reads

Clinical and microbiological effectiveness of photodynamic therapy on primary endodontic infections: a 6-month randomized clinical trial.

Clin Oral Investig 2018 May 7;22(4):1751-1761. Epub 2017 Nov 7.

Department of Medical Microbiology, Federal University of Rio de Janeiro, Institute of Microbiology Paulo de Góes, R. Soares Cabral, 63/702, Laranjeiras, Rio de Janeiro, RJ, CEP 22240070, Brazil.

Introduction: This short-term randomized controlled trial evaluated the effectiveness of photodynamic therapy (PDT) on clinical success (periapical healing) and on the microbiota of primary endodontic infections.

Methods: Thirty-two patients presenting mandibular molars with apical periodontitis (one tooth/patient) were selected and randomly allocated into two therapeutic groups: control (chemo-mechanical debridement [CMD]; n = 16) and PDT (CMD + PDT; n = 16). All teeth in both groups had intracanal medication with calcium hydroxide for 7 days before final obturation. Read More

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http://dx.doi.org/10.1007/s00784-017-2270-4DOI Listing
May 2018
7 Reads

Activities of Pexiganan and 10 Comparator Antimicrobials against 502 Anaerobic Isolates Recovered from Skin and Skin Structure Infections.

Antimicrob Agents Chemother 2017 12 22;61(12). Epub 2017 Nov 22.

R. M. Alden Research Laboratory, Culver City, California, USA.

Pexiganan, a cationic peptide, exhibited a broad range of anti-anaerobic antimicrobial activity. The MICs of studied isolates were as follows: , 16 μg/ml; other group spp., 4 μg/ml; and spp. Read More

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http://dx.doi.org/10.1128/AAC.01401-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700356PMC
December 2017
28 Reads

Bacterial isolates and antimicrobial susceptibilities from odontogenic abscesses in rabbits: 48 cases.

Vet Rec 2017 Nov 6;181(20):538. Epub 2017 Oct 6.

Departments of Medicine and Epidemiology, School of Veterinary Medicine, UC Davis Veterinary Medical Teaching Hospital, University of California, Davis, California, USA.

The medical record database of a veterinary teaching hospital was searched from 2000 through 2014 for records of client-owned rabbits with positive cultures from odontogenic abscesses. Data reviewed included sex, age, abscess location, sampling technique, previous antimicrobial treatments, microorganisms identified and antibiotic susceptibility of aerobic bacteria. Forty-eight client owned rabbits with one or more odontogenic abscesses and culture results were evaluated. Read More

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http://dx.doi.org/10.1136/vr.103996DOI Listing
November 2017
18 Reads

Factors Associated with Choice and Success of One- Versus Two-Stage Revision Arthroplasty for Infected Hip and Knee Prostheses.

HSS J 2017 Oct 26;13(3):224-231. Epub 2017 Apr 26.

Division of Infectious Diseases, University of Toronto, 26 Laidlaw St, Toronto, Ontario M6K1X2 Canada.

Background: Prosthetic joint infections (PJI) of hip and knee arthroplasties are becoming increasingly common with an aging population and an increasing demand for these procedures. Despite attempts at standardization, medical and surgical approaches vary widely among practitioners.

Questions/purposes: We first sought to determine if there were specific factors associated with choice of one- versus two-stage revision. Read More

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http://dx.doi.org/10.1007/s11420-017-9550-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617816PMC
October 2017
15 Reads