2,623 results match your criteria Peptostreptococcus Infection


Microbiota profile in new-onset pediatric Crohn's disease: data from a non-Western population.

Gut Pathog 2018 29;10:49. Epub 2018 Nov 29.

7Physics Department, Boston University, Boston, USA.

Background: The role of microbiota in Crohn's disease (CD) is increasingly recognized. However, most of the reports are from Western populations. Considering the possible variation from other populations, the aim of this study was to describe the microbiota profile in children with CD in Saudi Arabia, a non-Western developing country population. Read More

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November 2018
1 Read

Pharmacological inhibition of bacterial β-glucuronidase prevents irinotecan-induced diarrhea without impairing its antitumor efficacy in vivo.

Pharmacol Res 2018 Nov 1;139:41-49. Epub 2018 Nov 1.

Center for Biomarkers and Biotech Drugs, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Biomedical and Environmental Biology, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Institute of Biomedical Sciences, National Sun Yat-sen University, Kaohsiung 804, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan. Electronic address:

Irinotecan (CPT-11), a first-line chemotherapy for advanced colorectal cancer, causes serious diarrhea in patients receiving treatment. The underlying mechanism has been shown that the active metabolite of CPT-11, SN-38, is metabolized to the inactive metabolite SN-38 glucuronide (SN-38 G) during hepatic glucuronidation, and subsequently is exported into the intestine, where SN-38 G is hydrolyzed by bacterial β-glucuronidase (βG) to be SN-38, thus leading to intestinal toxicity. Thus, inhibition of the intestinal bacterial βG activity is expected to prevent CPT-11-induced diarrhea. Read More

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November 2018

Randomized controlled clinical study of veneered zirconia abutments for single implant crowns: Clinical, histological, and microbiological outcomes.

Clin Implant Dent Relat Res 2018 Dec 17;20(6):988-996. Epub 2018 Oct 17.

Clinic of Fixed and Removable Prosthodontics and Dental Material Science, Center of Dental Medicine, University of Zurich, Zürich, Switzerland.

Objectives: To analyze the effect of veneering of the submucosal part of zirconia abutments and the type of retention (cemented vs screw-retained) on clinical, microbiological, and histological outcomes of single-tooth implant crowns.

Material And Methods: A total of 44 patients with a single missing tooth to be replaced by an implant in the anterior region participated in the study. Implants were randomly assigned to receive zirconia-based CAD/CAM reconstructions using either one of four treatment modalities: cement-retained with submucosal veneering (CR-P), cement-retained without submucosal veneering (CR-W), screw-retained with submucosal veneering (SR-P), and screw-retained without submucosal veneering (SR-W). Read More

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December 2018

Affinity of Hyperammonia-Producing Bacteria To Produce Bioammonium/Ammonia Utilizing Five Organic Nitrogen Substrates for Potential Use as an Organic Liquid Fertilizer.

ACS Omega 2018 Sep 25;3(9):11817-11822. Epub 2018 Sep 25.

Department of Plant and Environmental Sciences, Horticulture, Clemson University Clemson Coastal Research and Education Center, 2700 Savannah Hwy, Charleston, South Carolina 29414, United States.

This research was conducted to create a plant-available nitrogen nutrient solution utilizing ruminant bacteria for ultimate use as a liquid nitrogen fertilizer for precision fertigation of vegetable crops. Three hyperammonia-producing ruminant bacteria, , and were cultured anaerobically using five different organic nitrogen substrates to determine their efficiency in producing bioammonium/ammonia (BAA), a term defined here as a biologically produced solution containing both ammonium and ammonia. These bacteria were chosen because of their ability to produce ammonium at rates not experienced by any other bacteria. Read More

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September 2018

Molecular analysis of oral microflora in patients with primary Sjögren's syndrome by using high-throughput sequencing.

PeerJ 2018 28;6:e5649. Epub 2018 Sep 28.

Department of Oral Biology, Peking University School and Hospital of Stomatology, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Key Laboratory of Digital Stomatology, Beijing, People's Republic of China.

Background: The objective of this study was to characterize the oral microflora profile of primary Sjögren's syndrome (pSS) patients, thereby revealing the connection between oral bacterial composition and dental caries, and to identify the "core microbiome" in the oral cavities of pSS patients and systemic healthy individuals by using a high-throughput sequencing technique.

Methods: Twenty-two pSS patients and 23 healthy controls were enrolled in this study. Their clinical data and oral rinse samples were collected. Read More

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September 2018
2 Reads

Orthodontic appliances did not increase risk of dental caries and periodontal disease under preventive protocol.

Angle Orthod 2018 Sep 21. Epub 2018 Sep 21.

Objectives:: To assess periodontal parameters and microbial species levels after orthodontic appliance placement in patients who received oral hygiene instructions and who were monitored and motivated throughout the study.

Materials And Methods:: The Periodontal Index was recorded and saliva collection was performed before (T0) and 30 (T1), 60 (T2), and 90 (T3) days after orthodontic appliance placement in 15 patients (mean age 17.53 ± 8. Read More

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September 2018

Clinical and microbiological features of bacteraemia with Gram-positive anaerobic cocci: a population-based retrospective study.

Clin Microbiol Infect 2018 Sep 11. Epub 2018 Sep 11.

Lund University, Faculty of Medicine, Department of Clinical Sciences, Division of Infection Medicine, Lund, Sweden; Skåne University Hospital, Division of Infection Medicine, Lund, Sweden. Electronic address:

Objectives: Gram-positive, anaerobic cocci (GPAC) can cause infections in humans. Only a few cases of bacteraemia with GPAC have been reported. We describe the clinical and microbiological characteristics of GPAC bacteraemia. Read More

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September 2018
10 Reads

Parvimonas micra bacteremia following endoscopic retrograde cholangiopancreatography: A new route of infection.

Anaerobe 2018 Sep 11;54:136-139. Epub 2018 Sep 11.

Microbiology and Virology Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy.

Parvimonas micra is an anaerobic, Gram-positive coccus belonging to oral, gastrointestinal and genital flora, rarely causing infections in humans. It was mainly deemed to cause bacteremia, septic bone and cerebral infections in patients which have undergone dental procedures or with suboptimal dental hygiene. We report the first case of Parvimonas micra bacteremia following endoscopic retrograde colangiopancreatography performed due to choledocholithiasis in a patient with good oral health. Read More

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September 2018
7 Reads

Real-time PCR quantification of 9 periodontal pathogens in saliva samples from periodontally healthy Korean young adults.

J Periodontal Implant Sci 2018 Aug 30;48(4):261-271. Epub 2018 Aug 30.

Department of Periodontology, Institute of Translational Dental Sciences, Pusan National University School of Dentistry, Yangsan, Korea.

Purpose: Few studies have examined periodontal pathogens from saliva samples in periodontally healthy young adults. The purposes of this study were to determine the prevalence of periodontopathic bacteria and to quantify periodontal pathogens in saliva samples using real-time polymerase chain reaction (PCR) assays in periodontally healthy Korean young adults under 35 years of age.

Methods: Nine major periodontal pathogens were analyzed by real-time PCR in saliva from 94 periodontally healthy young adults. Read More

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August 2018
3 Reads

Insights into the Populations of Proteolytic and Amino Acid-Fermenting Bacteria from Microbiota Analysis Using In Vitro Enrichment Cultures.

Curr Microbiol 2018 Nov 27;75(11):1543-1550. Epub 2018 Aug 27.

Laboratory of Gastrointestinal Microbiology, Jiangsu Key Laboratory of Gastrointestinal Nutrition and Animal Health, College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, 210095, China.

This study evaluated the effects of nitrogen source composition and monensin on the populations of proteolytic and amino acid-fermenting bacteria using in vitro enrichment culture. The experiment was designed with a 2 × 2 factorial arrangement: two nitrogen sources, casein (Cas) and tryptone (Try), and two levels of monensin, 0 (C) and 5 µmol/L (M), resulting in four treatments: Cas-C, Cas-M, Try-C, and Try-M. Ruminal fluid collected from three cannulated Holstein dairy cows was used as the inoculum. Read More

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November 2018
8 Reads

A Retrospective Analysis of Anaerobic Bacteria Isolated in 236 Cases of Pleural Empyema and their Prevalance of Antimicrobial Resistance in Turkey.

Clin Lab 2018 Jul;64(7):1269-1277

Background: Parapneumonic effusions usually occur secondary to an infection and produce pus (empyema) that accumulates in the pleural space. We aimed to evaluate the prevalence of anerobes in patients with empyema and to assess their resistance patterns for seven antimicrobials.

Methods: Pleural fluid specimens from 236 patients were inoculated on Schaedler agar. Read More

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July 2018
12 Reads

Comparison of the clinical and microbiological effects of antibiotic therapy in periodontal pockets following laser treatment: An in vivo study.

Adv Clin Exp Med 2018 Sep;27(9):1263-1270

Department of Dental Surgery, Wroclaw Medical University, Poland.

Background: Laser technology in periodontal therapy could help in reducing total bacterial count.

Objectives: The aim of this study was to evaluate the effects of pocket debridement using an erbium-doped yttrium aluminium garnet laser (Er:YAG laser - ERL), scaling and root planing (SRP) with photodynamic therapy (PDT), or SRP alone. Teeth vitality and soft tissue carbonization were also assessed. Read More

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September 2018

Clostridium difficile and Clostridioides difficile: Two validly published and correct names.

Anaerobe 2018 Aug 20;52:125-126. Epub 2018 Jul 20.

National Laboratory for Health, Environment and Food, NLZOH, Maribor, Slovenia; University of Maribor, Faculty of Medicine, Maribor, Slovenia. Electronic address:

The current status of the names Clostridium difficile and Clostridioides difficile is explained in view of the current confusion about the correct name of this well-known pathogen. Both names have been validly published under the provisions of the Prokaryotic Code and both names can be used. Read More

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August 2018
3 Reads

HPV infection and bacterial microbiota in the placenta, uterine cervix and oral mucosa.

Sci Rep 2018 Jun 28;8(1):9787. Epub 2018 Jun 28.

Department of Oral Pathology and Oral Radiology, Institute of Dentistry, Faculty of Medicine, University of Turku, Turku, Finland.

We investigated the association between HPV infection and bacterial microbiota composition in the placenta, uterine cervix and mouth in thirty-nine women. HPV DNA genotyping of 24 types was conducted using Multimetrix. Microbiota composition was characterized by 16S rRNA gene sequencing. Read More

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June 2018
1 Read

Peptostreptococcus canis and Bacteroides pyogenes prosthetic joint infection.

Enferm Infecc Microbiol Clin 2018 Jun 9. Epub 2018 Jun 9.

Unidad de Gestión Clínica de Enfermedades Infecciosas y Microbiología, Instituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen Macarena/Universidad de Sevilla/Centro Superior de Investigaciones Científicas (CSIC), Sevilla, España.

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Effects of co-composting of lincomycin mycelia dregs with furfural slag on lincomycin degradation, maturity and microbial communities.

Bioresour Technol 2018 Oct 26;265:155-162. Epub 2018 May 26.

Henan Xinxiang Hua Xing Pharmaceutical Factory, Xinxiang 453731, Henan, PR China.

This paper investigated the effect of co-composting of lincomycin mycelia dregs (LMDs) with furfural slag on the degradation of lincomycin, maturity and microbial communities. Results showed that after 66 days composting, the concentration of lincomycin was removed above 99%. The final pH, C/N and germination index (GI) all met the national standards in maturity. Read More

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October 2018
2 Reads

Nasal septal abscess caused by anaerobic bacteria of oral flora.

Auris Nasus Larynx 2018 Jun 7. Epub 2018 Jun 7.

Department of Otolaryngology, Kawasaki Medical School, Kurashiki, Japan. Electronic address:

Although nasal septal abscess (NSA) was formerly common, it has become rare since the development of antibiotics. NSA, if left untreated, can lead to intracranial complications such as meningitis and eventually result in saddle-nose deformity. NSA often occurs after injury, and indigenous skin bacteria such as Staphylococcus aureus are frequently detected. Read More

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June 2018
3 Reads

ent-Copalic acid antibacterial and anti-biofilm properties against Actinomyces naeslundii and Peptostreptococcus anaerobius.

Anaerobe 2018 Aug 28;52:43-49. Epub 2018 May 28.

Laboratory of Research in Applied Microbiology, University of Franca - UNIFRAN, Franca, São Paulo, Brazil. Electronic address:

Diterpenes are an important class of plant metabolites that can be used in the search for new antibacterial agents. ent-Copalic acid (CA), the major diterpene in Copaifera species exudates, displays several pharmacological properties. This study evaluates the CA antibacterial potential against the anaerobic bacteria Peptostreptococcus anaerobius and Actinomyces naeslundii. Read More

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August 2018
19 Reads

Characterization of the fecal and mucosa-associated microbiota in dogs with colorectal epithelial tumors.

PLoS One 2018 31;13(5):e0198342. Epub 2018 May 31.

Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences (NMBU), Oslo, Norway.

Colorectal epithelial tumors occur spontaneously in dogs, and the pathogenesis seems to parallel that of humans. The development of human colorectal tumorigenesis has been linked to alterations in the composition of the intestinal microbiota. This study characterized the fecal- and mucosa-associated microbiota in dogs with colorectal epithelial tumors (n = 10). Read More

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November 2018
1 Read

Laser reduction of specific microorganisms in the periodontal pocket using Er:YAG and Nd:YAG lasers: a randomized controlled clinical study.

Lasers Med Sci 2018 May 15. Epub 2018 May 15.

Department of Oral Medicine and Periodontology, Faculty of Medicine, University of Ljubljana, Hrvatski trg 6, 1000, Ljubljana, Slovenia.

The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned into one of three treatment groups of 20 patients. The first group received scaling and root planing by hand instruments (SRP group), the second group received Er:YAG laser treatment alone (Er group), and the third group received combined treatment with Nd:YAG and Er:YAG lasers (NdErNd group). Read More

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May 2018
17 Reads

Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer.

Gastroenterology 2018 08 3;155(2):383-390.e8. Epub 2018 May 3.

State Key Laboratory of Digestive Disease, Institute of Digestive Disease, Li Ka Shing Institute of Health Sciences, and CUHK Shenzhen Research Institute, The Chinese University of Hong Kong, Hong Kong; Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong. Electronic address:

Background & Aims: Colorectal cancer (CRC) development has been associated with increased proportions of Bacteroides fragilis and certain Streptococcus, Fusobacterium, and Peptostreptococcus species in the intestinal microbiota. We investigated associations between bacteremia from specific intestinal microbes and occurrence of CRC.

Methods: We performed a retrospective study after collecting data on 13,096 adult patients (exposed group) in Hong Kong hospitalized with bacteremia (identified by blood culture test) without a previous diagnosis of cancer from January 1, 2006 through December 31, 2015. Read More

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August 2018
4 Reads

Bacterial diversity in the feces of dogs with CPV infection.

Microb Pathog 2018 Aug 27;121:70-76. Epub 2018 Apr 27.

College of Veterinary Medicine, South China Agricultural University, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Key Laboratory of Prevention and Control for Severe Clinical Animal Diseases, Guangzhou, Guangdong Province, 510642, People's Republic of China; Guangdong Provincial Pet Engineering Technology Research Center, Guangzhou, Guangdong Province, 510642, People's Republic of China. Electronic address:

Canine parvovirus (CPV) is a contagious disease in dogs that has high morbidity and mortality. In cases of infection, the pups tend to have a higher mortality and more severe clinical symptoms than the adult dogs because the dehydration is difficult for pups to bear. Following the natural infection, there is a rapid antibody response neutralizing the extracellular virus. Read More

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Correlations between microbial communities in stool and clinical indicators in patients with metabolic syndrome.

World J Clin Cases 2018 Apr;6(4):54-63

Department of Research Service, Zhiyuan Medical Inspection Institute CO., LTD, Hangzhou 310030, Zhejiang Province, China.

Aim: To analyze the bacterial community structure and distribution of intestinal microflora in people with and without metabolic syndrome and combined these data with clinical indicators to determine relationships between selected bacteria and metabolic diseases.

Methods: Faecal samples were collected from 20 patients with metabolic syndrome and 16 controls at Cangnan People's Hospital, Zhejiang Province, China. DNA was extracted and the V3-V4 regions of the 16S rRNA genes were amplified for high throughput sequencing. Read More

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Anaerobic bacteria in wastewater treatment plant.

Int Arch Occup Environ Health 2018 07 28;91(5):571-579. Epub 2018 Mar 28.

Central Institute for Labour Protection-National Research Institute, 16 Czerniakowska St., 00-701, Warsaw, Poland.

Purpose: The objective of this study was to assess exposure to anaerobic bacteria released into air from sewage and sludge at workplaces from a wastewater treatment plant (WWTP).

Methods: Samples of both sewage and sludge were collected at six sampling points and bioaerosol samples were additionally collected (with the use of a 6-stage Andersen impactor) at ten workplaces covering different stages of the technological process. Qualitative identification of all isolated strains was performed using the biochemical API 20A test. Read More

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July 2018
1 Read

Characterization of the salivary microbiome in people with obesity.

PeerJ 2018 16;6:e4458. Epub 2018 Mar 16.

Department of Geriatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.

Background: The interactions between the gut microbiome and obesity have been extensively studied. Although the oral cavity is the gateway to the gut, and is extensively colonized with microbes, little is known about the oral microbiome in people with obesity. In the present study, we investigated the salivary microbiome in obese and normal weight healthy participants using metagenomic analysis. Read More

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March 2018
1 Read

Ageing with HIV - a periodontal perspective.

New Microbiol 2018 Jan;41(1):61-66

School of Dental Medicine, University of Belgrade, Serbia.

The importance of oral microflora composition in HIV-infected patients is well recognized. However, no studies so far have dealt with age-related changes in periodontal pathogens occurrence in HIV+ individuals. The aim of the present study was to assess and compare temporal changes of bacteria frequency in younger (≤35 years) and older (≥50 years) HIV-infected and non-infected individuals. Read More

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January 2018
8 Reads

Activities of Omadacycline and Comparators against Anaerobic Bacteria.

Antimicrob Agents Chemother 2018 Apr 27;62(4). Epub 2018 Mar 27.

Micromyx, Inc., Kalamazoo, Michigan, USA.

Omadacycline (OMC), a broad-spectrum aminomethylcycline, has shown clinical efficacy in anaerobic acute bacterial skin and skin structure infections (ABSSSI) and in animal models of intra-abdominal anaerobic infections. Here, the activity of OMC against clinically relevant anaerobes was similar to that of tigecycline, with MIC values of 1 to 8 μg/ml against spp., 0. Read More

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April 2018
2 Reads

Teenage boy with high fever and rash: what could we be missing?

BMJ Case Rep 2018 Feb 8;2018. Epub 2018 Feb 8.

Paediatric Intensive Care Unit, Hospital Pediátrico de Coimbra, Coimbra, Portugal.

A 15-year-old boy was admitted to a local hospital with high fever, generalised rash and a mild sore throat. He was started on intravenous flucloxacillin and 12 hours later develops a sustained low diastolic blood pressure (DBP), unresponsive to fluid volume expansion and cardiovascular support with dopamine. Intravenous clindamycin was added and transportation to paediatric intensive care unit arranged. Read More

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February 2018
5 Reads

Dietary proline supplementation alters colonic luminal microbiota and bacterial metabolite composition between days 45 and 70 of pregnancy in Huanjiang mini-pigs.

J Anim Sci Biotechnol 2018 30;9:18. Epub 2018 Jan 30.

1National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, Hunan 410125 China.

Background: Pregnancy is associated with important changes in gut microbiota composition. Dietary factors may affect the diversity, composition, and metabolic activity of the intestinal microbiota. Among amino acids, proline is known to play important roles in protein metabolism and structure, cell differentiation, conceptus growth and development, and gut microbiota re-equilibration in case of dysbiosis. Read More

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January 2018

Anaerobic bacterial meningitis in adults.

J Clin Neurosci 2018 Apr 1;50:45-50. Epub 2018 Feb 1.

Department of Neurology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address:

Anaerobic infection is a very uncommon condition in adult bacterial meningitis (ABM), and its clinical characteristics have yet to be clarified. We enrolled 540 patients with culture-proven bacterial meningitis during a study period of 30 years (1986-2015), of whom 13 (2.4%) had anaerobic infections. Read More

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April 2018
13 Reads

Fournier's Gangrene: Clinical Presentation of 13 Cases.

Med Sci Monit 2018 Jan 28;24:548-555. Epub 2018 Jan 28.

Department of General, Oncological and Functional Urology, Medical University of Warsaw, Warsaw, Poland.

BACKGROUND Fournier's gangrene (FG) is a fulminant form of infective, polymicrobial, necrotizing fasciitis of the perineal, genital, and perianal regions. It commonly affects men, but women and children may also develop this type of tissue necrosis. MATERIAL AND METHODS This study is a retrospective analysis of the management of 13 cases of Fournier's gangrene, diagnosed from among about 45 000 patients (men, women, and children) treated in the Department of General, Oncological, and Functional Urology (Medical University of Warsaw) from 1995 to 2013. Read More

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January 2018
9 Reads

Clinical and microbiological evaluation of the effect of Lactobacillus reuteri in the treatment of mucositis and peri-implantitis: A triple-blind randomized clinical trial.

J Periodontal Res 2018 Jun 19;53(3):378-390. Epub 2018 Jan 19.

Department of Periodontology, Universitat Internacional de Catalunya, Barcelona, Spain.

Background And Objective: Oral probiotics appear to improve the treatment of periodontal diseases but there is limited evidence on their efficacy in the treatment of peri-implant diseases. The objective of the present study was to evaluate, clinically and microbiologically, the effect of the oral probiotic, Lactobacillus reuteri Prodentis, as adjuvant to non-surgical mechanical therapy in implants with mucositis or peri-implantitis, placed in patients with a history of periodontal disease.

Material And Methods: A randomized, controlled, parallel-design, triple-blind prospective clinical study was designed. Read More

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June 2018
4 Reads

Risk of Infection After Allograft Anterior Cruciate Ligament Reconstruction: Are Nonprocessed Allografts More Likely to Get Infected? A Cohort Study of Over 10,000 Allografts.

Am J Sports Med 2018 Mar 3;46(4):846-851. Epub 2018 Jan 3.

Department of Orthopaedics, Southern California Permanente Medical Group, Baldwin Park, California, USA.

Background: Allograft tissue is frequently used in anterior cruciate ligament reconstruction (ACLR). It is often irradiated and/or chemically processed to decrease the risk of disease transmission, but some tissue is aseptically harvested without further processing. Irradiated and chemically processed allograft tissue appears to have a higher risk of revision, but whether this processing decreases the risk of infection is not clear. Read More

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March 2018
7 Reads

The oral microbiome-the relevant reservoir for acute pediatric appendicitis?

Int J Colorectal Dis 2018 Feb 22;33(2):209-218. Epub 2017 Dec 22.

Department of Pediatric Surgery, University of Leipzig, Liebigstr. 20A, 04103, Leipzig, Germany.

Purpose: The oral microbiome has been related to numerous extra oral diseases. Recent studies detected a high abundance of oral bacteria in inflamed appendices in pediatric patients. To elucidate the role of oral bacteria in acute pediatric appendicitis, we studied the oral and appendiceal microbiome of affected children compared to healthy controls. Read More

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February 2018
8 Reads

Subdural empyema caused by Peptostreptococcus sp.: a complication of acute pharyngitis.

Rev Inst Med Trop Sao Paulo 2017 Dec 21;59:e83. Epub 2017 Dec 21.

Tulane University, School of Public Health and Tropical Medicine, New Orleans, United States.

Subdural Empyema (ESD) is the collection of purulent fluid that develops between the exterior "dura mater" layer and the middle "arachnoid mater" layer that covers the brain. ESD can be caused by a primary infection located in the paranasal sinuses. In many aerobic and/or anaerobic bacterial cases, hearing or traumatic processes serve as the causative agent. Read More

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December 2017
5 Reads

High-resolution bacterial 16S rRNA gene profile meta-analysis and biofilm status reveal common colorectal cancer consortia.

NPJ Biofilms Microbiomes 2017 29;3:34. Epub 2017 Nov 29.

Johns Hopkins University School of Medicine, 1550 Orleans St., Baltimore, MD 21231 USA.

Colorectal cancer (CRC) remains the third most common cancer worldwide, with a growing incidence among young adults. Multiple studies have presented associations between the gut microbiome and CRC, suggesting a link with cancer risk. Although CRC microbiome studies continue to profile larger patient cohorts with increasingly economical and rapid DNA sequencing platforms, few common associations with CRC have been identified, in part due to limitations in taxonomic resolution and differences in analysis methodologies. Read More

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November 2017
8 Reads
6 Citations

Human Infection with without Jugular Venous Thrombosis: A Varied Presentation of Lemierre's Syndrome.

Case Rep Infect Dis 2017 24;2017:5358095. Epub 2017 Oct 24.

Critical Care Department, King Saud Medical City, Riyadh, Saudi Arabia.

Lemierre's syndrome is also known as postangina septicemia, which is commonly caused by also known as Necrobacillus and also by other microorganisms like , , , and . Though the disease starts as an upper respiratory tract infection, it may spread and cause thrombophlebitis of the internal jugular vein. It may present itself through cranial nerve palsy or sepsis involving distant organs like the lungs or bones. Read More

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October 2017
13 Reads

Bacterial alterations in salivary microbiota and their association in oral cancer.

Sci Rep 2017 Nov 28;7(1):16540. Epub 2017 Nov 28.

Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, 300, Taiwan.

Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity and the fourth leading malignancy and cause of cancer-related death in the male population of Taiwan. Most cases are detected at advanced stages, resulting in poor prognosis. Therefore, improved detection of early oral health disorders is indispensable. Read More

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November 2017
9 Reads

[Pathogen analysis in patients with diabetic foot osteomyelitis using 16S rRNA high-throughput sequencing].

Nan Fang Yi Ke Da Xue Xue Bao 2017 Nov;37(11):1448-1455

Department of Endocrinology and Metabolism, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China. E-mail:

Objective: To analyze the characteristics of pathogenic microorganisms in the infected bone tissues in patients with diabetic foot osteomyelitis (DFO) using 16S rRNA high-throughput sequencing to facilitate rapid and accurate detection of pathogens and effective infection control.

Methods: Between September, 2016 and April, 2017, 16 patients with DFO were admitted in our department and infected bone specimens were obtained during debridement. The pathogenic microorganisms in the specimens were identified using both 16S rRNA high-throughput sequencing and automatic blood culture analyzer, and the characteristics of the microflora were analyzed based on 16S rRNA sequencing data in comparison with the results of blood culture. Read More

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November 2017
12 Reads

Fusobacterium emphysematous pyomyositis with necrotizing fasciitis of the leg presenting as compartment syndrome: a case report.

J Med Case Rep 2017 Nov 28;11(1):332. Epub 2017 Nov 28.

Department of Surgery, University of Illinois at Chicago, Chicago, 60612, IL, USA.

Background: Fusobacterium necrophorum is a common agent of disease in humans, but the occurrence of primary infections outside the head and neck area is extremely rare. While infection with Fusobacterium necrophorum has a rather benign course above the thorax, the organism is capable of producing very severe disease when located in unusual sites, including various forms of septic thrombophlebitis. No infections of the leg have been documented before; thus, antibiotic coverage for Fusobacterium is currently not recommended in this area. Read More

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November 2017
18 Reads

Pyogenic Brain Abscess Caused by Peptostreptococcus in a Patient with HIV-1 Infection.

Diseases 2017 Nov 17;5(4). Epub 2017 Nov 17.

Gilead Sciences, Miami, FL 33136, USA.

In the setting of HIV, cerebral lesions are usually secondary to lymphoma and opportunistic infections; however, in patients with CD4 counts above 200 cells/uL, other pathologies such as pyogenic brain abscess could gain importance. The microbiology of pyogenic brain abscess has and as the leading etiologic pathogens in immunocompetent individuals. is also recognized as a common cause of brain abscess in this patient population. Read More

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November 2017
3 Reads

Septic arthritis of knee joint due to micra.

BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.

Internal Medicine, Section of Infectious Diseases, University of Illinois College of Medicine at Peoria, Peoria, Illinois, USA.

species are anaerobic, Gram-positive cocci that are a constituent of normal oral and gastrointestinal flora. We present a case of right knee joint septic arthritis due to in an immunocompromised patient. A 61-year-old male renal and pancreatic transplant recipient on immunosuppressive therapy was admitted to our hospital due to intense pain, joint swelling and inability to move his right knee over the past 9 months. Read More

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November 2017
10 Reads

Clinical and microbiological effectiveness of photodynamic therapy on primary endodontic infections: a 6-month randomized clinical trial.

Clin Oral Investig 2018 May 7;22(4):1751-1761. Epub 2017 Nov 7.

Department of Medical Microbiology, Federal University of Rio de Janeiro, Institute of Microbiology Paulo de Góes, R. Soares Cabral, 63/702, Laranjeiras, Rio de Janeiro, RJ, CEP 22240070, Brazil.

Introduction: This short-term randomized controlled trial evaluated the effectiveness of photodynamic therapy (PDT) on clinical success (periapical healing) and on the microbiota of primary endodontic infections.

Methods: Thirty-two patients presenting mandibular molars with apical periodontitis (one tooth/patient) were selected and randomly allocated into two therapeutic groups: control (chemo-mechanical debridement [CMD]; n = 16) and PDT (CMD + PDT; n = 16). All teeth in both groups had intracanal medication with calcium hydroxide for 7 days before final obturation. Read More

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May 2018
4 Reads

[Microbial flora and antibiotic susceptibility of purulent tooth diseases in rabbits].

Authors:
Anja Ewringmann

Tierarztl Prax Ausg K Kleintiere Heimtiere 2017 Nov 3;45(6). Epub 2017 Nov 3.

Dr. Anja Ewringmann, Praxis für kleine Heimtiere, Potsdamer Straße 1, 12205 Berlin, E-Mail:

Objective: Bacteria involved in purulent tooth disease and the most effective antibiotics were investigated.

Material And Methods: Swab samples were taken from 126 rabbits with facial abscesses or purulent periapical inflammation during surgical treatment. Bacteriological examination and susceptibility testing were performed. Read More

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November 2017

Effects of dietary Greek oregano (Origanum vulgare ssp. hirtum) supplementation on rumen fermentation, enzyme profile and microbial communities in goats.

Authors:
N Paraskevakis

J Anim Physiol Anim Nutr (Berl) 2018 Jun 14;102(3):701-705. Epub 2017 Oct 14.

Department of Animal Physiology and Nutrition, Agricultural University of Athens, Athens, Greece.

This study was conducted to examine in vivo long-term effects of dietary dried oregano (Origanum vulgare ssp. hirtum) whole plant on rumen fermentation, enzyme profile and microbial communities. For this purpose, eight healthy, adult, non-lactating Alpine goats were kept in tie stalls equipped for individual feeding and randomly divided into two homogeneous groups: one fed 0. Read More

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June 2018
1 Read

Activities of Pexiganan and 10 Comparator Antimicrobials against 502 Anaerobic Isolates Recovered from Skin and Skin Structure Infections.

Antimicrob Agents Chemother 2017 12 22;61(12). Epub 2017 Nov 22.

R. M. Alden Research Laboratory, Culver City, California, USA.

Pexiganan, a cationic peptide, exhibited a broad range of anti-anaerobic antimicrobial activity. The MICs of studied isolates were as follows: , 16 μg/ml; other group spp., 4 μg/ml; and spp. Read More

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December 2017
15 Reads

The oral microbiota in colorectal cancer is distinctive and predictive.

Gut 2018 08 7;67(8):1454-1463. Epub 2017 Oct 7.

APC Microbiome Institue, University College Cork, National University of Ireland, Cork, Ireland.

Background And Aims: Microbiota alterations are linked with colorectal cancer (CRC) and notably higher abundance of putative oral bacteria on colonic tumours. However, it is not known if colonic mucosa-associated taxa are indeed orally derived, if such cases are a distinct subset of patients or if the oral microbiome is generally suitable for screening for CRC.

Methods: We profiled the microbiota in oral swabs, colonic mucosae and stool from individuals with CRC (99 subjects), colorectal polyps (32) or controls (103). Read More

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August 2018
6 Reads

Bacterial isolates and antimicrobial susceptibilities from odontogenic abscesses in rabbits: 48 cases.

Vet Rec 2017 Nov 6;181(20):538. Epub 2017 Oct 6.

Departments of Medicine and Epidemiology, School of Veterinary Medicine, UC Davis Veterinary Medical Teaching Hospital, University of California, Davis, California, USA.

The medical record database of a veterinary teaching hospital was searched from 2000 through 2014 for records of client-owned rabbits with positive cultures from odontogenic abscesses. Data reviewed included sex, age, abscess location, sampling technique, previous antimicrobial treatments, microorganisms identified and antibiotic susceptibility of aerobic bacteria. Forty-eight client owned rabbits with one or more odontogenic abscesses and culture results were evaluated. Read More

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November 2017
8 Reads

Factors Associated with Choice and Success of One- Versus Two-Stage Revision Arthroplasty for Infected Hip and Knee Prostheses.

HSS J 2017 Oct 26;13(3):224-231. Epub 2017 Apr 26.

Division of Infectious Diseases, University of Toronto, 26 Laidlaw St, Toronto, Ontario M6K1X2 Canada.

Background: Prosthetic joint infections (PJI) of hip and knee arthroplasties are becoming increasingly common with an aging population and an increasing demand for these procedures. Despite attempts at standardization, medical and surgical approaches vary widely among practitioners.

Questions/purposes: We first sought to determine if there were specific factors associated with choice of one- versus two-stage revision. Read More

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October 2017
7 Reads