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    2267 results match your criteria Penile Squamous Cell Carcinoma

    1 OF 46

    Testicular germ-cell tumours and penile squamous cell carcinoma: Appropriate management makes the difference.
    Eur J Surg Oncol 2018 Feb 14. Epub 2018 Feb 14.
    Evaluative Epidemiology Unit, Fondazione IRCCS, Istituto Nazionale dei Tumori, Milan, Italy.
    Germ-cell tumours (GCT) of the testis and penile squamous cell carcinoma (PeSCC) are a rare and a very rare uro-genital cancers, respectively. Both tumours are well defined entities in terms of management, where specific recommendations - in the form of continuously up-to-dated guide lines-are provided. Impact of these tumour is relevant. Read More

    [Penile cancer: diagnosis and staging].
    Urologe A 2018 Mar 9. Epub 2018 Mar 9.
    Urologische Klinik und Poliklinik, Universitätsmedizin Rostock, Ernst-Heydemann-Str. 6, 18057, Rostock, Deutschland.
    Penile cancer is often an obvious visual diagnosis but histologic verification should be obtained prior to treatment. The clinical examination should determine the tumor stage and whether it has infiltrated the cavernous bodies and/or the urethra and it should adequately assess the inguinal lymph nodes. Preoperative imaging of the lesion is only indicated in equivocal cases. Read More

    Treatment Trends and Outcomes for Patients With Lymph Node-Positive Cancer of the Penis.
    JAMA Oncol 2018 Mar 1. Epub 2018 Mar 1.
    Department of Hematology/Oncology, Fox Chase Cancer Center, Temple Health, Philadelphia, Pennsylvania.
    Importance: Penile cancer is an uncommon disease with minimal level I evidence to guide therapy. The National Comprehensive Cancer Network (NCCN) guidelines advocate a lymph node dissection (LND) or radiotherapy with consideration of perioperative chemotherapy for all patients with lymph node-positive (LN+) penile cancer without metastasis.

    Objectives: To determine temporal trends in use of chemotherapy for patients with LN+ penile cancer without metastasis and to evaluate outcomes between those who did or did not receive LND, chemotherapy, and radiotherapy. Read More

    [Human papillomavirus and penile cancer : Thinking about measures for prevention].
    Urologe A 2018 Feb 26. Epub 2018 Feb 26.
    Klinikum der Universität München, Großhadern, München, Deutschland.
    Two major pathways of penile carcinogenesis are known: human papillomavirus (HPV)-induced penile cancer and HPV-negative cancers associated with chronic dermatoses. Therefore, modern measures for prevention of penile cancer may for example include prophylactic HPV vaccination. The resulting B‑cell-mediated immunity to HPV capsid proteins is effective protection against future HPV infections. Read More

    Simultaneous Occurrence of Balanoposthitis Circumscripta Plasmacellularis Zoon, Phimosis andCarcinoma of the Penis: Case Report with An Unusual Ulcerated Polypoid Variant of Zoon's Disease and a Carcinomaof Reserve Cell Type.
    Open Access Maced J Med Sci 2018 Jan 31;6(1):61-63. Epub 2017 Dec 31.
    Università Degli Studi "G. Marconi", Rome, Italy.
    Background: Zoon's balanitis is a benign disease characterized by an asymptomatic, chronic, solitary, shiny, red-orange plaque of the glans and/ or prepuce. In rare cases of Zoon's disease, penile squamous cell carcinoma developed in the chronic inflammatory lesions.

    Case Report: We report on a 68-year-old male patient presenting with phimosis and coexistent Zoon's disease and penile carcinoma in situ treated successfully by circumcision. Read More

    Long-term incidence trends of HPV-related cancers, and cases preventable by HPV vaccination: a registry-based study in Norway.
    BMJ Open 2018 02 23;8(2):e019005. Epub 2018 Feb 23.
    Department of Research, Cancer Registry of Norway, Oslo, Norway.
    Objectives: Examine long-term incidence trends of human papillomavirus (HPV)-related cancer in Norway, and estimate the number of cancer cases preventable by vaccines against HPV 16/18 or HPV 16/18/31/33/45/52/58.

    Design: Observational registry-based study. We extracted incident cases of HPV-related cancer during 1953-2015 from the Cancer Registry of Norway. Read More

    [Molecular characterization of penile cancer : Literature review of new prognostic markers and potential therapeutic targets].
    Urologe A 2018 Feb 22. Epub 2018 Feb 22.
    Urologische Klinik, Caritas-Krankenhaus St. Josef, Universität Regensburg, Regensburg, Deutschland.
    Squamous cell carcinoma of the penis (SCCP) is a rare cancer type in Western industrialized nations; nevertheless, it shows an aggressive course of disease in advanced tumor stages with accordantly high recurrence and progression rates. While molecular biomarkers are not established in clinical routine for the management of SCCP patients yet, the accordant unmet need is enormous, as adequate biomarkers would be meaningful for prognostic determination, planning of modality and extent of primary therapy, indication for inguinal lymph node resection, adjuvant treatment, and as potential targets for specific systemic treatment. SCCP regularly develops from a precursor lesion. Read More

    [Pathology and histopathological evaluation of penile cancer].
    Urologe A 2018 Feb 21. Epub 2018 Feb 21.
    Institut für Pathologie, Universitätsmedizin Rostock, Strempelstraße 14, 18057, Rostock, Deutschland.
    Background: Penile cancer is rare in Germany and in western European countries. Our understanding of the pathogenesis and pathology of this malignancy has increased considerably in recent years.

    Objectives: Clinical management has become more complex, with organ-preserving strategies being increasingly favored. Read More

    Giant genital warts.
    Clin Case Rep 2018 Feb 5;6(2):444-445. Epub 2018 Jan 5.
    2nd Department of SurgerySchool of MedicineAretaieion University HospitalNational and Kapodistrian University of Athens University of Athens76 Vassilisis Sofia's AveAthens11528Greece.
    Genital warts are quite common and should be treated early with nonaggressive conservative or invasive methods. When they are severely neglected patients may be submitted to amputative surgical management. Preoperatively malignant transformation of the tumors cannot be excluded. Read More

    Surgical and Oncological Outcomes in Patients After Vascularised Flap Reconstruction for Locoregionally Advanced Penile Cancer.
    Eur Urol Focus 2018 Feb 9. Epub 2018 Feb 9.
    Department of Urology, Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address:
    Background: Treatment of locoregionally advanced penile squamous cell carcinoma (LAPSCC) is challenging. The exact role (in terms of oncological benefit) of extensive surgery is not well established. Moreover, surgery invariably leads to large defects requiring reconstructive surgery. Read More

    Pulsed-dye laser therapy for carcinoma in situ of the penis.
    Br J Dermatol 2018 Jan 24. Epub 2018 Jan 24.
    Department of Dermatology and Venereology, Medical University of Graz, Graz, Austria.
    Carcinoma in situ (CIS) of the penis is a precancerous condition with a 5 to 10% risk for progression into an invasive penile squamous cell carcinoma (SCC). Clinical variants of genital CIS encompass bowenoid papulosis, erythroplasia of Queyrat and Bowen's disease. Treatment options of penile CIS include topical application of 5-fluorouracil (5-FU) or imiquimod, photodynamic therapy (PDT), ablative laser therapy, cryotherapy and surgery. Read More

    "Double trouble" - synchronous mantle cell lymphoma and metastatic squamous cell carcinoma in an inguinal lymph node.
    Pol J Pathol 2017;68(3):270-274
    Multiple primary neoplasms may also occur synchronously. Lymphoma may coexist with second malignant tumor in its primary location or malignant tumor may metastases to lymphomatous lymph nodes. Most often lymphoid component is a low grade lymphoma and coexistence of mantle cell lymphoma (MCL) and second malignant tumor is much rarer. Read More

    Validation of predictors for lymph node status in penile cancer: Results from a population-based cohort.
    Can Urol Assoc J 2017 Dec 22. Epub 2017 Dec 22.
    Department of Oncology, Queen's University, Cancer Centre of Southeastern Ontario at Kingston General Hospital, Kingston, ON; Canada.
    Introduction: The ability to predict lymph node (LN) status is essential in the management of men with localized squamous cell carcinoma (SCC) of the penis. There has been limited external validation of available risk stratification tools, particularly in routine clinical care. The objective of this study was to evaluate the predictive variables of LN metastases within a large population-based cohort of patients. Read More

    Histological subtype is a significant predictor for inguinal lymph node metastasis in patients with penile squamous cell carcinoma.
    Asian J Androl 2017 Dec 29. Epub 2017 Dec 29.
    Department of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei 230601, China.
    The present study aimed to investigate the relationship between histopathological subtype and the probability of inguinal lymph node metastasis (ILNM) in patients with penile squamous cell carcinoma (PSCC). The clinical records of 198 consecutive patients with PSCC were analyzed retrospectively. Primary lesions were reevaluated according to the 2016 World Health Organization (WHO) histopathological classification. Read More

    Racial disparity and survival outcomes between African-American and Caucasian American men with penile cancer.
    BJU Int 2017 Dec 27. Epub 2017 Dec 27.
    Department of Urology, University of Miami Leonard M. Miller School of Medicine, Miami, FL, USA.
    Objective: To determine whether there is a survival difference for African-American men (AAM) versus Caucasian American men (CM) with penile squamous cell carcinoma (pSCC), particularly in locally advanced and metastatic cases where disease mortality is highest.

    Patients And Methods: Using the Florida Cancer Data System, we identified men with pSCC from 2005 to 2013. We compared age, follow-up, stage, race, and treatment type between AAM and CM. Read More

    Differences in Survival by Receipt of Lymph Node Dissection in Patients with Invasive Penile Cancer: Results from NCDB.
    J Urol 2017 Dec 15. Epub 2017 Dec 15.
    Division of Urologic Oncology, Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
    Purpose: Inguinal lymphadenectomy remains under performed in patients with invasive penile cancer. Using a large national cancer registry we assessed temporal trends in inguinal lymphadenectomy performance and evaluated the impact of the procedure on survival in patients in whom inguinal lymphadenectomy was an absolute indication (T1b-4 N0/x-1) according to NCCN (National Comprehensive Cancer Network®) Guidelines®.

    Materials And Methods: We queried NCDB (National Cancer Database) for all cases of nonmetastatic, T1b-4 N0/X-N1 squamous cell carcinoma of the penis from 2004 to 2014. Read More

    Trends in incidence, mortality and survival of penile squamous cell carcinoma in Norway 1956-2015.
    Int J Cancer 2018 Apr 15;142(8):1586-1593. Epub 2017 Dec 15.
    Department of Research, Cancer Registry of Norway, Oslo, Norway.
    We examine trends in incidence, mortality and survival of penile squamous cell carcinoma (SCC) in Norway over 60 years. Data on all cases of penile cancer diagnosed in Norway during 1956-2015 were obtained from the Cancer Registry of Norway. Trends in age-standardized rates of penile SCC incidence, mortality and 5-year relative survival were assessed by the annual percentage change statistic and joinpoint regression. Read More

    Thulium-yttrium-aluminium-garnet (Tm:YAG) laser treatment of penile cancer: oncological results, functional outcomes, and quality of life.
    World J Urol 2018 Feb 2;36(2):265-270. Epub 2017 Dec 2.
    Department of Urology, Istituto Europeo di Oncologia, Via Ripamonti 435, Milan, Italy.
    Purpose: To evaluate the oncological and functional outcomes of patients diagnosed with penile cancer undergoing conservative treatment through thulium-yttrium-aluminium-garnet (Tm:YAG) laser ablation.

    Methods: Twenty-six patients with a penile lesion underwent ablation with a RevoLix 200 W continuous-wave laser. The procedure was carried out with a pen-like laser hand piece, using a 360 μm laser fiber and 15-20 W of power. Read More

    Combined Partial Penectomy With Bilateral Robotic Inguinal Lymphadenectomy Using Near-infrared Fluorescence Guidance.
    Urology 2018 Mar 27;113:251. Epub 2017 Nov 27.
    Department of Urology, University of Miami Miller School of Medicine, Miami, FL. Electronic address:
    Objective: To describe our novel technique for performing a combined partial penectomy and bilateral robotic inguinal lymphadenectomy using intraoperative near-infrared (NIR) fluorescence guidance with indocyanine green (ICG) and the DaVinci Firefly camera system.

    Methods: A 58-year-old man presented status post recent excisional biopsy of a 2-cm lesion on the left coronal aspect of the glans penis. Pathology revealed "invasive squamous cell carcinoma of the penis with multifocal positive margins. Read More

    Contemporary role of radiotherapy in the management of penile cancer.
    Transl Androl Urol 2017 Oct;6(5):855-867
    British Columbia Cancer Agency, Center for the Southern Interior, Kelowna, BC, Canada.
    Penile cancer is a rare clinical entity that contributes to significant patient morbidity and mortality. Human papilloma virus (HPV) plays an important role in the carcinogenesis of penile squamous cell carcinoma (SCC), is associated with improved clinical outcomes, and is predictive for response to treatment with chemotherapy and radiotherapy. Historically, treatment consisted of radical surgery with partial or total penectomy. Read More

    Beyond chemotherapy for advanced disease-the role of EGFR and PD-1 inhibitors.
    Transl Androl Urol 2017 Oct;6(5):848-854
    Department of Urology, Fudan University Shanghai Cancer Center, Shanghai, China.
    Penile squamous cell carcinoma (SCC) is a rare malignancy with limited treatment options when the tumor is unresectable and/or chemorefractory. Triplet systemic chemotherapy regimens including taxane and cisplatin are recommended, but the response duration can be short and the treatment-related toxicity high. Only a small proportion of patients survive 1 year or longer with the current standard treatment paradigm. Read More

    Robotic inguinal lymphadenectomy for penile cancer: the why, how, and what.
    Transl Androl Urol 2017 Oct;6(5):826-832
    Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL, USA.
    Squamous cell carcinoma of the penis (SCC-P) demonstrates a reliable pattern of spread to the lymph nodes of the groin. High grade and higher stage (pT1b or greater) SCC-P demonstrate a higher propensity for metastasis to the inguinal lymph nodes. Further, lymphadenopathy progresses in a predictable fashion, from superficial inguinal lymph nodes to deep inguinal lymph nodes to pelvic lymph nodes, with limited survival noted for those patients with progression to pelvic lymph nodes. Read More

    Topical Therapy for non-invasive penile cancer (Tis)-updated results and toxicity.
    Transl Androl Urol 2017 Oct;6(5):803-808
    Department of Urology, St George's Hospital, London, UK.
    Penile cancer is a rare malignancy estimated to affect 26,000 men globally each year. The association with penile cancer, in particular non-invasive disease, and human papilloma virus (HPV) is well known. Ninety-five percent of cases of penile cancer are squamous cell carcinoma (SCC), which are staged using the TNM staging system. Read More

    Prevalence of oncogenic human papillomavirus genotypes in patients diagnosed with anogenital malignancies in Botswana.
    BMC Infect Dis 2017 Nov 25;17(1):731. Epub 2017 Nov 25.
    Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Botswana, Private Bag UB072, 4775 Notwane Rd., Gaborone, Botswana.
    Background: Human papillomavirus (HPV) associated malignancies are the leading cause of cancer death in Botswana. We sought to determine causative HPV types in patients with anogenital malignancies in Botswana to inform vaccine strategy.

    Methods: We used formalin-fixed and paraffin-embedded (FFPE) tissue blocks from patients diagnosed with anal, penile and vulvar squamous cell carcinomas between the years, 2014 and 2016. Read More

    APOBEC3A Expression in Penile Squamous Cell Carcinoma.
    Pathobiology 2017 Nov 23. Epub 2017 Nov 23.
    Section of Molecular Urooncology, Department of Urology, Medical Faculty Heidelberg, University of Heidelberg, Heidelberg, Germany.
    Background: APOBECs (apolipoprotein B mRNA-editing catalytic polypeptides) are cytidine deaminases that have been implicated in the host defense against viruses by blocking viral replication. They have also been shown to play a role in genome hypermutation in several human cancers. An APOBEC3 hypermutation signature has been discovered in cervical cancer, which is intimately associated with infection by high-risk human papillomaviruses (HPVs). Read More

    Video Endoscopic Inguinal Lymphadenectomy vs Open Inguinal Lymphadenectomy for Carcinoma Penis: Expanding Role and Comparison of Outcomes.
    Urology 2018 Mar 16;113:79-84. Epub 2017 Nov 16.
    Department of Urology and Renal Transplantation, SMS Medical College, Jaipur, Rajasthan, India.
    Objective: To compare differences of morbidity profile, oncological yield, and efficacy between video endoscopic inguinal lymphadenectomy and open inguinal lymphadenectomy cases.

    Materials And Methods: A total of 29 patients with proven squamous cell carcinoma of the penis were selected for inguinal lymphadenectomy from August 2013 to January 2017. Video endoscopic lymphadenectomy was performed on 1 limb and open inguinal lymphadenectomy was performed on the contralateral side. Read More

    Penile warty mucoepidermoid carcinoma with features of stratified mucin-producing intra-epithelial lesion and invasive stratified mucin-producing carcinoma.
    Histopathology 2018 Apr 14;72(5):867-873. Epub 2018 Jan 14.
    Department of Pathology, Charles University, Medical Faculty and Charles University Hospital Plzen, Pilsen, Czech Republic.
    Aims: Stratified mucin-producing intra-epithelial lesion (SMILE) and invasive stratified mucin-producing carcinoma (ISMC) are recently described cervical and penile lesions. We report an unusual case of mixed variant of penile squamous cell carcinomas with warty, usual and mucoepidermoid SMILE/ISMC features.

    Methods And Results: A 62-year-old Japanese man had a glans penis lesion of one-and-a-half years' duration, suggesting malignancy. Read More

    Successful downstaging of locally recurrent penile squamous cell carcinoma with neoadjuvant nanosomal docetaxel lipid suspension (NDLS) based regimen followed by curative surgery.
    BMJ Case Rep 2017 Nov 12;2017. Epub 2017 Nov 12.
    Department of Medical Affairs and Clinical Research, Intas Pharmaceuticals Limited, Ahmedabad, India.
    Penile squamous cell carcinoma (pSCC) is a relatively rare disease in Western world but is a significant health problem in developing countries like India. We report here a case of successful multimodality management of recurrent pSCC with pelvic lymphadenopathy in a 56-year-old male patient with poorly controlled diabetes. The patient presented with ulceroproliferative growth over the residual penile stump clinically involving root of penis and with right pelvic lymphadenopathy. Read More

    Penile Sparing Surgery for Penile Cancer: A Multicenter International Retrospective Cohort.
    J Urol 2017 Nov 11. Epub 2017 Nov 11.
    Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida. Electronic address:
    Purpose: We evaluated recurrence outcomes of penile sparing surgery in what is to our knowledge the largest multicenter cohort of patients to date.

    Materials And Methods: We retrospectively identified patients treated with penile sparing surgery from May 1990 to July 2016 at 5 tertiary referral institutions. Treatments consisted of circumcision, wide local excision, laser therapy with or without local excision, partial or total glansectomy and glans resurfacing. Read More

    CD109 expression is upregulated in penile squamous cell carcinoma.
    Oncol Lett 2017 Nov 15;14(5):6012-6016. Epub 2017 Sep 15.
    Medical Research Center, Shandong Provincial Qianfoshan Hospital, Shandong University, Jinan, Shandong 250014, P.R. China.
    Cluster of differentiation (CD) 109 is a glycosylphosphatidylinositol-anchored cell surface glycoprotein and a co-receptor for transforming growth factor β. The expression of CD109 has been detected in squamous cell carcinoma of the lung, esophagus, skin and gallbladder. The aim of the present study was to evaluate CD109 expression in penile squamous cell carcinoma (PSCC). Read More

    Impact of County Rurality and Urologist Density on the Practice of Inguinal Lymph Node Dissection and Mortality in Patients Diagnosed with Squamous Cell Carcinoma of the Penis.
    Ann Surg Oncol 2018 Jan 6;25(1):334-341. Epub 2017 Nov 6.
    Urologic Oncology, Department of Urology, Henry Ford Health System, Detroit, MI, USA.
    Background: Inguinal lymphadenectomy (LND) is influential in reducing the mortality of squamous cell carcinoma of the penis (SCCP). We investigated the impact of urologic workforce density (UD) and rural residence (RR) on the practice of LND and mortality of SCCP (SCCP-RM).

    Materials And Methods: UD was determined from the 2014 to 2015 Area Health Resource File data, while RR was determined using the 2003 rural-urban continuum codes. Read More

    Five-year relative survival for human papillomavirus-associated cancer sites.
    Cancer 2018 Jan 6;124(1):203-211. Epub 2017 Nov 6.
    National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia.
    Background: Human papillomavirus (HPV) vaccines can potentially prevent greater than 90% of cervical and anal cancers as well as a substantial proportion of vulvar, vaginal, penile, and oropharyngeal cancers caused by certain HPV types. Because more than 38,000 HPV-associated cancers are diagnosed annually in the United States, current studies are needed to understand how relative survival varies for each of these cancers by certain demographic characteristics, such as race and age.

    Methods: The authors examined high-quality data from 27 population-based cancer registries covering approximately 59% of the US population. Read More

    The World Health Organisation 2016 classification of penile carcinomas: a review and update from the International Society of Urological Pathology expert-driven recommendations.
    Histopathology 2017 Nov 3. Epub 2017 Nov 3.
    Department of Cellular Pathology, St George's Healthcare NHS Foundation Trust, London, UK.
    The International Society of Urological Pathology (ISUP) held an expert-driven penile cancer conference in Boston in March 2015, which focused on the new World Health Organisation (WHO) classification of penile cancer: human papillomavirus (HPV)-related tumours and histological grading. The conference was preceded by an online survey of the ISUP members, and the results were used to initiate discussions. Because of the rarity of penile tumours, this was not a consensus but an expert-driven conference aimed at assisting pathologists who do not see these tumours on a regular basis. Read More

    Insight into novel biomarkers in penile cancer: Redefining the present and future treatment paradigm?
    Urol Oncol 2017 Nov 2. Epub 2017 Nov 2.
    Departments of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL. Electronic address:
    Introduction: Biomarkers are increasingly used in the diagnosis and management of various malignancies. Selected biomarkers may also play a role in management of certain cases of penile carcinoma. In this article, we provide an overview of the clinical role of such markers in the management of penile cancer. Read More

    Laser ablation as monotherapy for penile squamous cell carcinoma: A multi-center cohort analysis.
    Urol Oncol 2017 Oct 30. Epub 2017 Oct 30.
    Department of Genitourinary Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL.
    Introduction: Although the trend towards penile sparing therapy is increasing for penile squamous cell carcinoma, outcomes for laser ablation therapy have not been widely reported. We assessed the clinical outcomes of penile cancer patients treated with only laser ablation.

    Materials And Methods: A retrospective review was performed on 161 patients across 5 multi-center tertiary referral centers from 1985 to 2015. Read More

    Benefits of Urologic-Dermatologic Consultations for the Diagnosis of Cutaneous Penile Lesions: A Prospective Study.
    Clin Genitourin Cancer 2017 Oct 5. Epub 2017 Oct 5.
    Department of Urology, Angers University Hospital, Angers, France.
    Introduction: We evaluated the benefits of a specialized consultation created in 2014 for cutaneous penile lesions.

    Materials And Methods: We performed a descriptive prospective study evaluating all patients sent for a monthly urologic-dermatologic consultation at a French university hospital from September 2014 to September 2015 for cutaneous penile lesions. All patients evaluated were included. Read More

    Monitoring the impact of HPV vaccine in males-Considerations and challenges.
    Papillomavirus Res 2016 Dec 17;2:106-111. Epub 2016 May 17.
    University of British Columbia and BC Women's Hospital and Health Centre, 4500 Oak Street, Vancouver, BC, Canada V6H 3N1.
    In this article, we examine the issues involved if national or sub-national programs are considering extending post HPV vaccine introduction monitoring to include males. Vaccination programs are now being extended to include males in some countries, in order to improve population level HPV infection control and to directly prevent HPV-related disease in males such as anogenital warts and anal cancers. Coverage and adverse events surveillance are essential components of post-vaccination monitoring. Read More

    Management of penile cancer in a Singapore tertiary hospital.
    Arab J Urol 2017 Jun 30;15(2):123-130. Epub 2017 Mar 30.
    Tan Tock Seng Hospital, Singapore, Singapore.
    Objectives: To present our experience of managing penile squamous cell carcinoma (SCC) in a tertiary hospital in Singapore and to evaluate the prognostic value of the inflammatory markers neutrophil-lymphocyte ratio (NLR) and lymphocyte-monocyte ratio (LMR).

    Patients And Methods: We reviewed our prospectively maintained Institutional Review Board-approved urological cancer database to identify men treated for penile SCC at our centre between January 2007 and December 2015. For all the patients identified, we collected epidemiological and clinical data. Read More

    Saphenous-sparing laparoscopic inguinal lymphadenectomy.
    Int Braz J Urol 2017 Oct 24;43. Epub 2017 Oct 24.
    San Bassiano Hospital - Urology, Bassano del Grappa, Italy.
    Introduction: Inguinal lymphadenectomy is an integral part in the management of penile cancer. Video endoscopic in-guinal lymphadenectomy (VEIL) is emerging as a minimally invasive treatment to reduce postoperative complications.

    Materials And Methods: 62 years old man underwent glansectomy for a squamous cell carcinoma (pT1b). Read More

    Oral Human Papillomavirus Infection: Differences in Prevalence Between Sexes and Concordance With Genital Human Papillomavirus Infection, NHANES 2011 to 2014.
    Ann Intern Med 2017 Nov 17;167(10):714-724. Epub 2017 Oct 17.
    From University of Florida, Gainesville, Florida; Baylor College of Medicine and The University of Texas Health Science Center at Houston School of Public Health, Houston, Texas; Harvard Medical School, Boston, Massachusetts; and Weill Cornell Medicine, New York, New York.
    Background: The burden of human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) is disproportionately high among men, yet empirical evidence regarding the difference in prevalence of oral HPV infection between men and women is limited. Concordance of oral and genital HPV infection among men is unknown.

    Objective: To determine the prevalence of oral HPV infection, as well as the concordance of oral and genital HPV infection, among U. Read More

    Cancer incidence in Germany attributable to human papillomavirus in 2013.
    BMC Cancer 2017 Oct 16;17(1):682. Epub 2017 Oct 16.
    Department of Epidemiology and Health Monitoring, Robert Koch-Institut, Berlin, Germany.
    Background: It is estimated that a total of 120,000 new cancer cases in men and in women in more developed countries could be avoided if exposure to HPV was prevented. We used the nationwide pool of German population-based cancer registry data to estimate the burden of HPV-attributable cancer in this population for the year 2013.

    Methods: Incident cases of cervical cancer, squamous cell carcinoma of the anus, oropharynx (OP), as well as of the vulva, vagina and penis were classified as potentially HPV-associated and identified from the nationwide cancer registry data-pool. Read More

    Evaluating the accuracy of intraoperative frozen section during inguinal lymph node dissection in penile cancer.
    Urol Oncol 2018 Jan 9;36(1):14.e1-14.e5. Epub 2017 Oct 9.
    Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL.
    Introduction: Inguinal lymph node dissection is an integral part in the management of invasive penile tumors with intraoperative assessment often aiding decision-making during dissection. In this study, we evaluate the diagnostic value of intraoperative frozen section (FS) and analyze clinicopathologic factors that affect its accuracy.

    Material And Methods: We, retrospectively, reviewed 84 patients with squamous cell carcinoma of the penis who underwent inguinal lymph node dissection at our institution. Read More

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