10,560 results match your criteria Pemphigus Foliaceus


Visual Dermatology: Pemphigus Vegetans.

J Cutan Med Surg 2020 Jun 30:1203475420936656. Epub 2020 Jun 30.

433816 Clinical Department of Dermatology, Faculty of Medicine and Pharmacy, "Dunărea de Jos" University of Galati, Romania.

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http://dx.doi.org/10.1177/1203475420936656DOI Listing

Diagnostic value of cytology in oral ulcer and comparison with histopathology and direct immunofluorescence.

Dermatol Ther 2020 Jun 30:e13929. Epub 2020 Jun 30.

Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Rapid diagnosis of pemphigus vulgaris (PV) is an important task in patient's prognosis and treatment. Although PV is routinely diagnosed through investigation of pathology specimens and direct immunofluorescence assays, Tzanck smear can be used as rapid, inexpensive and easily used test to confirm its clinical diagnosis. This study aimed to determine the diagnostic value of Tzanck smear in erosive oral lesions of PV and determination of its sensitivity and specificity for diagnostic purposes. Read More

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http://dx.doi.org/10.1111/dth.13929DOI Listing

Pemphigus vegetans localised to the soles of both feet: Successful clearance with intralesional corticosteroid.

Australas J Dermatol 2020 Jun 30. Epub 2020 Jun 30.

Department of Dermatology, 306 Hospital of PLA, Beijing, China.

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http://dx.doi.org/10.1111/ajd.13355DOI Listing

Expression of PD-1 and Tim-3 is increased in skin of patients with bullous pemphigoid and pemphigus vulgaris.

J Eur Acad Dermatol Venereol 2020 Jun 28. Epub 2020 Jun 28.

Department of Dermatology, University of Luebeck, Luebeck, Germany.

Background: Bullous pemphigoid (BP) and pemphigus vulgaris (PV) are common autoimmune bullous dermatoses (AIBD) characterized by blisters and erosions. Treatment options are limited and often insufficient. Immune checkpoint receptors play critical roles in immune homeostasis and self- tolerance. Read More

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http://dx.doi.org/10.1111/jdv.16780DOI Listing

COVID-19 in pemphigus vulgaris patients with previous rituximab therapy: A tele-medicine experience.

J Dermatolog Treat 2020 Jun 27:1-7. Epub 2020 Jun 27.

Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Nowadays, rituximab, an anti-CD20 monoclonal antibody, has revolutionized the treatment of moderate to severe pemphigus from both safety and efficacy perspectives. We aimed to perform a tele-dermatology study to evaluate the development of COVID-19 or its associated symptoms in pemphigus vulgaris (PV) patients who received rituximab treatment within five years from the initiation of pandemic. This cross-sectional study was performed on May 2020 with tele-medicine follow-up method in our center. Read More

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http://dx.doi.org/10.1080/09546634.2020.1789041DOI Listing

"Conformational anti-desmoglein 3 ELISA is not superior to conventional anti-desmoglein 3 ELISA for disease monitoring in patients with pemphigus vulgaris- A longitudinal study."

J Am Acad Dermatol 2020 Jun 24. Epub 2020 Jun 24.

Departments of Dermatology, Jawaharlal Institute of Postgraduate medical education and research (JIPMER), Pondicherry. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.06.072DOI Listing

Rituximab in childhood and juvenile autoimmune bullous diseases as first-line and second-line treatment: a case series of 13 patients.

J Dermatolog Treat 2020 Jun 26:1-21. Epub 2020 Jun 26.

Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.

: Little data are available concerning the outcome of rituximab (RTX) therapy in pediatric patients with autoimmune bullous diseases (AIBDs).: We sought to evaluate safety and efficacy of RTX administration in pediatric patients with AIBDs and to assess first-line RTX therapy in pemphigus patients.: AIBD patients consisting of 12 pemphigus patients and a patient with bullous pemphigoid who received RTX before the age of 18 were enrolled. Read More

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http://dx.doi.org/10.1080/09546634.2020.1788702DOI Listing

Imatinib induced superficial pemphigus in a patient with gastrointestinal stromal tumor (GIST).

Dermatol Ther 2020 Jun 26. Epub 2020 Jun 26.

Department of Dermatology, Centre de référence des Maladies Bulleuses Auto-immunes - CNR MALIBUL CHU Dupuytren 16 Rue Bernard Descottes 87 042 LIMOGES, France.

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http://dx.doi.org/10.1111/dth.13903DOI Listing

Implication of phototherapy for rare comorbidity of psoriasis and pemphigus foliaceus; case report and review of literature.

Dermatol Ther 2020 Jun 23. Epub 2020 Jun 23.

Division of Dermatology, Department of Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan.

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http://dx.doi.org/10.1111/dth.13889DOI Listing

Miracles of Herbal Phytomedicines in Treatment of Skin Disorders: Natural Healthcare Perspective.

Infect Disord Drug Targets 2020 Jun 22. Epub 2020 Jun 22.

Institute of Pharmaceutical Research, GLA University, Mathura-281406, Uttar Pradesh. India.

Human skin considered as the first line of defense and barrier against the majority of infections caused through the skin that are affecting human populations. Healthy skin, promotes healthy body that can achieve with the usage of modern, allopathic and natural remedies. Major skin ailments affecting human populations are skin cancers, eczema, herpes infection, fungal infection, anti-aging, itching, insect bites, pemphigus vulgaris, trauma, psoriasis, athlete's foot infections, rashes, skin pigmentation, acne, major and minor wound infections that are slowly becoming a burden on health care. Read More

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http://dx.doi.org/10.2174/1871526520666200622142710DOI Listing

Extensive Verrucae over Healed Pemphigus Vulgaris Lesions in an Immunocompetent Female: A Rare Presentation of Wolf's Isotopic Response.

Indian J Dermatol 2020 May-Jun;65(3):211-213

Department of Skin and VD, Smt SCL General Hospital, Ahmedabad, Gujarat, India.

Wolf's isotopic response refers to the occurrence of a skin disorder at the site of another unrelated and already healed skin disease. The cases described so far in the literature include herpes (simplex or zoster) as the primary disease in most cases and a myriad of skin diseases as the secondary disease. Here, we report a case where extensive verrucae developed over the sites of healed lesions of pemphigus vulgaris, in an immunocompetent female. Read More

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http://dx.doi.org/10.4103/ijd.IJD_384_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292444PMC

Rituximab in autoimmune pemphigoid diseases: Indications, optimized regimens, and practice gaps.

Clin Dermatol 2020 May - Jun;38(3):384-396. Epub 2019 Jul 26.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida, USA. Electronic address:

Rituximab is a monoclonal antibody targeting CD20 on B cells with proven efficacy for pemphigus vulgaris, now an FDA-approved indication. Other autoimmune bullous diseases can be challenging to treat and have significant associated morbidity and mortality, but data supporting the use of rituximab in pemphigoid group diseases remain limited. Although rituximab demonstrates efficacy for clinical improvement and remission in pemphigoid, concern for adverse events may also limit the use of this medication. Read More

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http://dx.doi.org/10.1016/j.clindermatol.2019.07.023DOI Listing

Patients with specific skin disorders who are affected by COVID-19: what do experiences say about management strategies? : A systematic review.

Dermatol Ther 2020 Jun 18:e13867. Epub 2020 Jun 18.

Department of Dermatology, Rasoul Akram Hospital, Iran University of Medical Sciences (IUMS), Tehran, Iran.

Background And Aim: In patients with dermatologic disorders who are affected by new corona virus, we know little about course (underlying disease and new onset-infection) and the most proper management strategies include both issues that are what this systematic review targets.

Method: Databases of PubMed, Scopus, Google Scholar, Medscape and CEBD coronavirus dermatology resource of Nottingham University searched completely and initial 237 articles selected to further review and finally nine articles (including 12 patients) entered to this study.

Result: from 12 patients with chronic underlying dermatologic disease treated with systemic therapies, only one patient required ICU admission, the others have been treated for mild- moderate symptoms with conventional therapies. Read More

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http://dx.doi.org/10.1111/dth.13867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323037PMC

Pemphigus foliaceous triggered by topical diclofenac.

Australas J Dermatol 2020 Jun 18. Epub 2020 Jun 18.

Dermatology Department, Mater Misericordiae University Hospital, Dublin 7, Ireland.

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http://dx.doi.org/10.1111/ajd.13339DOI Listing

Correlation of IgG autoantibodies against acetylcholine receptors and desmogleins in patients with pemphigus treated with steroid sparing agents or rituximab.

PLoS One 2020 18;15(6):e0233957. Epub 2020 Jun 18.

Department of Dermatology, Duke University School of Medicine, Durham, North Carolina, United States of America.

Introduction: Autoantibodies (autoAbs) against desmoglein-1 (DSG1) and desmoglein-3 (DSG3) have conventionally been studied and well accepted in the pathogenesis of pemphigus vulgaris (PV) and foliaceus (PF). Recent studies have suggested that non-DSG autoAbs may contribute to the pathogenesis of pemphigus, including autoAbs directed at acetylcholine receptors (AChR) and thyroid peroxidase (TPO). The purpose of this study is to retrospectively analyze PV and PF patient sera to better understand the relationship between anti-AChR and -TPO Abs to disease activity and DSG reactivity between patients treated with prednisone and steroid sparing agents (SSA; n = 22) or prednisone and rituximab (n = 21). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0233957PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302486PMC

Erythroderma: a prospective study of 309 patients followed for 12 years in a tertiary center.

Sci Rep 2020 Jun 17;10(1):9774. Epub 2020 Jun 17.

Division of Clinical Dermatology, Hospital das Clínicas, University of São Paulo Medical School, São Paulo, Brazil.

Erythroderma is characterized by erythema and scaling affecting more than 80% of the body surface area. It is potentially life-threatening, and diagnosis of the underlying disease is a challenge. Despite laboratory improvements, many cases remain idiopathic. Read More

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http://dx.doi.org/10.1038/s41598-020-66040-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300014PMC

The effects of immunostimulatory herbal supplements on autoimmune skin diseases.

J Am Acad Dermatol 2020 Jun 15. Epub 2020 Jun 15.

Corporal Michael J. Crescenz VAMC, Philadelphia, PA; Department of Dermatology, University of Pennsylvania, Philadelphia, PA. Electronic address:

The use of herbal supplements that promise to improve immune health has gained popularity among dermatology patients. However, there is little to no evidence that herbal supplements improve dermatological conditions. Several in vitro and in vivo studes have shown that Spirulina platensis, Aphanizomenon flos-aqua, Chlorella, Echinacea, and alfalfa activate immune cells, via certain cytokines and chemokines. Read More

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http://dx.doi.org/10.1016/j.jaad.2020.06.037DOI Listing
June 2020
4.449 Impact Factor

Autoimmune Pathology in Myasthenia Gravis Disease Subtypes Is Governed by Divergent Mechanisms of Immunopathology.

Front Immunol 2020 27;11:776. Epub 2020 May 27.

Department of Neurology, School of Medicine, Yale University, New Haven, CT, United States.

Myasthenia gravis (MG) is a prototypical autoantibody mediated disease. The autoantibodies in MG target structures within the neuromuscular junction (NMJ), thus affecting neuromuscular transmission. The major disease subtypes of autoimmune MG are defined by their antigenic target. Read More

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http://dx.doi.org/10.3389/fimmu.2020.00776DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274207PMC

[Modern diagnostics of autoimmune bullous diseases].

Pathologe 2020 Jul;41(4):317-325

Klinik für Dermatologie, Allergologie und Venerologie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

Blisters and erosions of skin and mucous membranes are key features of the clinically heterogeneous group of autoimmune bullous diseases (AIBDs). These can be divided into pemphigoid diseases with autoantibodies against structural proteins of the dermal-epidermal junction, pemphigus diseases with autoantibodies against desmosomal proteins, and dermatitis herpetiformis with autoantibodies against transglutaminases 1 and 2. A differentiation based only on clinical features is often not sufficient. Read More

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http://dx.doi.org/10.1007/s00292-020-00795-8DOI Listing

The effectiveness of rituximab in pemphigus, and the benefit of additional maintenance infusions: daily practice data from a retrospective study.

J Am Acad Dermatol 2020 Jun 12. Epub 2020 Jun 12.

Department of Dermatology, Center for Blistering Diseases, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jaad.2020.06.024DOI Listing

Recalcitrant pemphigus successfully treated with lenalidomide.

Eur J Dermatol 2020 Apr;30(2):178-179

Department of Dermatology and Venereology, Universität Leipzig.

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http://dx.doi.org/10.1684/ejd.2020.3715DOI Listing

CORRIGENDUM to Individuals with the Rare Disease Pemphigus: A Quest for Diagnostic.

Authors:

Qual Health Res 2020 Jun 12:1049732320935081. Epub 2020 Jun 12.

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http://dx.doi.org/10.1177/1049732320935081DOI Listing

Autoimmune mucocutaneous blistering diseases in the south of Italy: a 25-year retrospective study on 169 patients.

J Oral Pathol Med 2020 Jun 12. Epub 2020 Jun 12.

Department of Neurosciences, Reproductive Sciences and Dentistry, Federico II University of Naples, Naples, Italy.

Background: Autoimmune mucocutaneous blistering diseases (AMBDs) represent a heterogeneous group of organ-specific and potentially life-threatening diseases. We sought to determine the relationship between clinical remission and therapeutic regimens with clinical type and phenotype of AMBDs, as well as clinical outcomes achieved based on different therapeutic regimens.

Methods: A retrospective single-center study on 169 AMBDs patients, including pemphigus vulgaris (PV), mucous membrane pemphigoid (MMP), paraneoplastic autoimmune multiorgan syndrome (PAMS), and lichen planus pemphigoides (LPP), was performed from 1994 to 2019 in an oral medicine tertiary center, where we collected sociodemographic data, clinical type and phenotype, prescribed therapies, and related outcomes. Read More

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http://dx.doi.org/10.1111/jop.13059DOI Listing

Increased expression of in situ IL-31RA and circulating CXCL8 and CCL2 in pemphigus herpetiformis suggests participation of the IL-31 family in the pathogenesis of the disease.

J Eur Acad Dermatol Venereol 2020 Jun 12. Epub 2020 Jun 12.

Departamento de Dermatologia, Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, SP, Brazil.

Background: Pemphigus herpetiformis (PH) is a rare clinical subtype of pemphigus with the presence of urticarial plaques, severe pruritus, rare acantholysis and eosinophilic spongiosis.

Objectives: The aim of this study was to investigate the influence of IL-31 and proinflammatory cytokines/chemokines in the pathogenesis of PH.

Methods: Twenty-five patients with PH and three groups: pemphigus foliaceus (PF=14), pemphigus vulgaris (PV=15) and healthy controls (HC=20) were selected for this study. Read More

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http://dx.doi.org/10.1111/jdv.16730DOI Listing

Topical insulin in the treatment of non-healing erosions and ulcers of pemphigus vulgaris.

Authors:
Manoj Pawar

J Am Acad Dermatol 2020 Jun 8. Epub 2020 Jun 8.

Skin Clinic, Nashik. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2020.05.149DOI Listing

Successful treatment of pemphigus foliaceous and ankylosing spondylitis with infliximab and methotrexate: A case report.

Dermatol Ther 2020 Jun 10:e13801. Epub 2020 Jun 10.

Department of Dermatology, EskiŞehir Osmangazi University Faculty of Medicine.

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http://dx.doi.org/10.1111/dth.13801DOI Listing

Rituximab induced reticulate pigmentation over face in Pemphigus Vulgaris.

Dermatol Ther 2020 Jun 10:e13752. Epub 2020 Jun 10.

Department of Dermatology and STD, Lady Hardinge Medical College, New Delhi, India.

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http://dx.doi.org/10.1111/dth.13752DOI Listing
June 2020
1.478 Impact Factor

Clinical presentation and diagnostic delay in pemphigus vulgaris: A prospective study from Turkey.

J Oral Pathol Med 2020 Jun 9. Epub 2020 Jun 9.

Department of Dermatology and Venereology, Faculty of Medicine, Akdeniz University, Antalya, Turkey.

Background: To evaluate the diagnostic patterns and factors that may influence delays in the diagnosis of pemphigus vulgaris (PV) with oral involvement.

Materials And Methods: In this prospective cohort study, 36 newly diagnosed PV patients with oral involvement were clinically examined and interviewed about the natural history of the oral lesions, number of medical consultations (Med consultation), medical treatment history, and diagnostic delay time (DD time).

Results: Thirty (83%) PV patients presented initially with oral mucosal involvement (OMI) and 6 (17%) presented initially with skin involvement (SI). Read More

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http://dx.doi.org/10.1111/jop.13052DOI Listing

A case with buccal squamous cell carcinoma that developed pemphigus vulgaris induced by radiotherapy.

Dermatol Ther 2020 Jun 8:e13783. Epub 2020 Jun 8.

Department of Dermatology Diseases, Necmettin Erbakan University Meram Faculty of Medicine.

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http://dx.doi.org/10.1111/dth.13783DOI Listing

Unusual external auditory canal relapse in pemphigus vulgaris.

JAAD Case Rep 2020 Jun 24;6(6):549-551. Epub 2020 Apr 24.

Department of Neuroscience, Reproductive and Odontostomatological Sciences, Oral Medicine Unit, Federico II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1016/j.jdcr.2020.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263999PMC

Retrospective analysis of 45 cases of localized retroperitoneal Castleman disease from a single center.

Hepatobiliary Surg Nutr 2020 Jun;9(3):304-311

Department of General Surgery, Peking University First Hospital, Beijing 100034, China.

Background: Castleman disease (CD) is a rare lymphoproliferative disease characterized by high heterogeneity in clinical manifestation and prognosis. This study aimed to summarize clinical features of localized retroperitoneal CD and our experiences to improve the diagnosis and treatment of this disease.

Methods: Clinical data of 45 patients with localized retroperitoneal CD were retrospectively analyzed. Read More

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http://dx.doi.org/10.21037/hbsn.2019.05.05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262626PMC

Evaluation of desmoglein 1 and 3 autoantibodies in pemphigus vulgaris: correlation with disease severity.

J Clin Exp Dent 2020 May 1;12(5):e440-e445. Epub 2020 May 1.

Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Background: Pemphigus is an autoimmune blistering disease of the skin and mucous membranes caused by autoantibodies against desmoglein 1 (Dsg1) and desmoglein 3 (Dsg3). Pemphigus vulgaris (PV) is the most common form of pemphigus. The aim of this study was to assess the correlation between the levels of anti-desmoglein 1 and 3 autoantibodies and the severity of PV disease. Read More

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http://dx.doi.org/10.4317/jced.56289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263783PMC

Skin - a vast organ with immunological function (Review).

Exp Ther Med 2020 Jul 20;20(1):18-23. Epub 2020 Mar 20.

Department of Physiology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.

The skin is an organ with multiple functions, where important inflammatory and immunological processes take place. The integrity of the skin barrier is necessary for it to fulfill its roles. An intact skin barrier requires a physiological keratinization process, but also a normal cutaneous microbial flora. Read More

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http://dx.doi.org/10.3892/etm.2020.8619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271707PMC

Primary bandages for people with pemphigus vulgaris lesions: an integrative literature review.

Rev Gaucha Enferm 2020 1;41:e20190259. Epub 2020 Jun 1.

Hospital do Câncer I, Instituto Nacional de Câncer José Alencar Gomes da Silva, Rio de Janeiro, Rio de Janeiro, Brasil.

Objective: To identify the primary bandages recommended in the literature to dress the wounds of people with pemphigus vulgaris and to describe the positive or negative repercussions related to these bandages.

Method: Integrative literature review, using the descriptors "dressing", "nursing care", "nursing", "skin diseases / vesiculobollous" and "pemphigus"; inclusion criteria: articles that address primary bandages for pemphigus vulgaris skin lesion dressing; published between 2010 and 2017; in Portuguese, English or Spanish; indexed in BDENF, LILACS, PubMed, and/or Scopus.

Results: eight articles were selected, seven had evidence levels 4 and 5 and one had evidence level 3. Read More

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http://dx.doi.org/10.1590/1983-1447.2020.20190259DOI Listing

Identification of ATP2C1 mutations in the patients of Hailey-Hailey disease.

BMC Med Genet 2020 Jun 1;21(1):120. Epub 2020 Jun 1.

Department of Otolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Xi'an Jiaotong University, NO. 157 Xi Wu Road, Xi'an, 710004, Shaan'xi Province, China.

Background: Familial benign chronic pemphigus, also known as Hailey-Hailey disease (HHD), is a clinically rare bullous Dermatosis. However the mechanism has not been clarified. The study aim to detect novel mutations in exons of ATP2C1 gene in HHD patients; to explore the possible mechnism of HHD pathogenesis by examining the expression profile of hSPCA1, miR-203, p63, Notch1 and HKII proteins in the skin lesions of HHD patients. Read More

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http://dx.doi.org/10.1186/s12881-020-01056-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268385PMC
June 2020
2.083 Impact Factor

Dry Eye and Quantitative and Qualitative Changes of Meibomian Glands in Patients With Pemphigus.

Cornea 2020 May 29. Epub 2020 May 29.

Department of Ophthalmology, Ege University Faculty of Medicine, Izmir, Turkey.

Purpose: To evaluate dry eye and quantitative and qualitative changes of meibomian glands with meibography in patients with pemphigus.

Methods: Twenty left eyes of 20 patients with pemphigus (group 1) and 20 left eyes of 20 age- and sex-matched healthy volunteers (group 2) were enrolled. Dry eye was evaluated with Oxford scale scoring, tear film breakup time, Schirmer 1 tests, and Ocular Surface Disease Index score assessments. Read More

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http://dx.doi.org/10.1097/ICO.0000000000002356DOI Listing

Flame Figures in Linear Immunoglobulin A Bullous Dermatosis Secondary to Parvovirus B19 Infection.

Am J Dermatopathol 2020 May 28. Epub 2020 May 28.

Departments of Dermatology, and.

Flame figures represent a characteristic but nondiagnostic histological finding in eosinophilic dermatoses. Some bullous autoimmune diseases with a predominant eosinophilic infiltrate, such as bullous pemphigoid, pemphigoid gestationis, and pemphigus vegetans, may show them. However, it is rare to find them in predominant neutrophilic bullous dermatoses such as linear immunoglobulin A. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001690DOI Listing

Neonatal pemphigus.

J Paediatr Child Health 2020 May 29. Epub 2020 May 29.

Department of Dermatology, Liverpool Hospital, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/jpc.14917DOI Listing

Pemphigus foliaceus complicated by sepsis of the aetiology of after eating cheesecake.

Postepy Dermatol Alergol 2020 Feb 11;37(1):111-113. Epub 2018 Oct 11.

Department of Dermatology, Poznan University of Medical Sciences, Poznan, Poland.

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http://dx.doi.org/10.5114/ada.2018.78880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247066PMC
February 2020

Nineteen-year retrospective evaluation of pemphigus in a single dermatology centre in Istanbul, Turkey.

Postepy Dermatol Alergol 2020 Feb 9;37(1):23-28. Epub 2020 Mar 9.

Departments of Dermatology, Istanbul Medeniyet University, Istanbul, Turkey.

Introduction: Pemphigus is an autoimmune intra-epidermal bullous disease of the skin and mucosae.

Aim: To retrospectively evaluate the course, prognosis and clinical features of pemphigus.

Material And Methods: The files of 196 pemphigus patients admitted to our clinic between December 1995 and December 2014 were collected and analysed. Read More

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http://dx.doi.org/10.5114/ada.2020.93380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7247063PMC
February 2020

Pemphigus Vulgaris: A Retrospective Cohort Study of Clinical Features, Treatments, and Outcomes.

Actas Dermosifiliogr 2020 May 25. Epub 2020 May 25.

Servicio de Dermatología, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Background: Pemphigus vulgaris (PV) is an uncommon, serious disease that is treated with systemic corticosteroids and corticosteroid-sparing agents.

Objectives: To describe and analyze the demographic and clinical characteristics of patients with PV.

Material And Methods: Retrospective cohort study of adults diagnosed with PV over a period of 12years. Read More

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http://dx.doi.org/10.1016/j.ad.2019.10.004DOI Listing

Functional inhibition of regulatory CD4 CD25 T cells in peripheral blood of patients with pemphigus vulgaris.

Clin Exp Dermatol 2020 May 27. Epub 2020 May 27.

Department of Dermatology, Huadong Hospital Affiliated with Fudan University, Shanghai, 200040, China.

Background: Pemphigus vulgaris (PV) is a potentially life-threatening autoimmune bullous disease affecting the skin and mucous membranes, whose pathogenic mechanism is still not fully understood. Regulatory T cells (Tregs) have been reported to play a significant role in regulating immune homeostasis in autoimmune disorders, such as PV.

Aim: To investigate the potential role of Tregs in the immunopathogenesis of PV. Read More

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http://dx.doi.org/10.1111/ced.14309DOI Listing

Predominant Stroma-Rich Feature in Hyaline Vascular Variant of Castleman Disease Is Associated With Paraneoplastic Pemphigus.

Am J Clin Pathol 2020 May 27. Epub 2020 May 27.

Department of Dermatology, Peking University First Hospital, Beijing, China.

Objectives: We aimed to describe the clinical and histopathologic features of Castleman disease (CD), particularly emphasizing its associations with paraneoplastic pemphigus (PNP) and prognosis.

Methods: We retrospectively enrolled 123 CD patients at our center. Clinical, pathologic, and laboratory data were reviewed. Read More

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http://dx.doi.org/10.1093/ajcp/aqaa053DOI Listing

Gastrointestinal involvement of primary skin diseases.

J Eur Acad Dermatol Venereol 2020 May 26. Epub 2020 May 26.

Center for Research & Development, Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan.

Less is known about gastrointestinal (GI) involvement of primary skin diseases due to the difference in embryology, histology, microbiology and physiology between integument and alimentary tract. Oesophagus, following the oropharyngeal mucosa, is the most common GI segment affected by primary skin diseases, especially by eosinophilic oesophagitis, lichen planus and autoimmune bullous dermatoses like pemphigus vulgaris, mucosal membrane pemphigoid and epidermolysis bullosa acquisita. Eosinophilic oesophagitis is an emerging chronic atopic disease with oesophageal dysfunction as the typical presentation, and oesophageal narrowing, rings and stricture as late complications. Read More

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http://dx.doi.org/10.1111/jdv.16676DOI Listing

Low prevalence of late-onset neutropenia following rituximab treatment in patients with pemphigus.

J Am Acad Dermatol 2020 May 22. Epub 2020 May 22.

Lübeck Institute of Experimental Dermatology and Center for Research on Inflammation of the Skin, University of Lübeck, Germany.

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http://dx.doi.org/10.1016/j.jaad.2020.05.076DOI Listing

[Pemphigoid reaction by specific allergen immunotherapy: An unusual adverse reaction].

Rev Alerg Mex 2020 Jan-Mar;67(1):83-86

Instituto de Investigación Sanitaria, Servicio de Alergología, Hospital Universitario La Paz, Madrid, España.

Background: For the most part, adverse reactions caused by subcutaneous allergen-specific immunotherapy (AIT) are directly induced by the administration of an allergen; there is usually redness and induration at the area of the injection. Other skin lesions are extremely unusual.

Case Report: A 40-year-old woman with allergic rhinoconjunctivitis and asthma due to sensitization to grass pollen had received monthly doses of 0. Read More

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http://dx.doi.org/10.29262/ram.v67i1.671DOI Listing

Anti-colitic effects of Physalin B on dextran sodium sulfate-induced BALB/c mice by suppressing multiple inflammatory signaling pathways.

J Ethnopharmacol 2020 Sep 19;259:112956. Epub 2020 May 19.

Zhejiang Provincial Key Laboratory for Drug Evaluation and Clinical Research, Research Center for Clinical Pharmacy, First Affiliated Hospital, College of Medicine, Zhejiang University, 79# Qingchun Road, Hangzhou, 310003, PR China. Electronic address:

Ethnopharmacological Relevance: Physalin B is one of the main active withanolide existed in Physalis alkekengi L. var. franchetii (Mast. Read More

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http://dx.doi.org/10.1016/j.jep.2020.112956DOI Listing
September 2020

Visual Dermatology: Scalp Involvement in Pemphigus Vegetans.

J Cutan Med Surg 2020 May 22:1203475420928927. Epub 2020 May 22.

91475 Department of Dermatology, Hospital Pakar Sultanah Fatimah, Muar, Johor, Malaysia.

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http://dx.doi.org/10.1177/1203475420928927DOI Listing