Evaluation of prolactin levels in patients with newly diagnosed pemphigus vulgaris and its correlation with pemphigus disease area index.
- Vahideh Lajevardi,
- Zahra Hallaji,
- Maryam Daneshpazhooh,
- Narges Ghandi,
- Peyman Shekari,
- Sepideh Khani
Int J Womens Dermatol 2016 Jun 23;2(2):53-55. Epub 2016 Apr 23.
Department of Dermatology, Tehran University of Medical Sciences, Tehran, Iran.
Background: Prolactin is a hormone; in addition to it known roles, it has immunomodulatory effects on lymphocytes maturation and immunoglobulins production. Hyperprolactinemia has been demonstrated in various autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, type I diabetes mellitus, and Graves' disease. In view of the prolactin immunomodulatory roles, studying prolactin levels in pemphigus as an autoimmune blistering disease may introduce new ways of understanding disease etiology and developing treatment strategies. Read More