688 results match your criteria Pemphigoid Gestationis


Flame Figures in Linear Immunoglobulin A Bullous Dermatosis Secondary to Parvovirus B19 Infection.

Am J Dermatopathol 2020 May 28. Epub 2020 May 28.

Departments of Dermatology, and.

Flame figures represent a characteristic but nondiagnostic histological finding in eosinophilic dermatoses. Some bullous autoimmune diseases with a predominant eosinophilic infiltrate, such as bullous pemphigoid, pemphigoid gestationis, and pemphigus vegetans, may show them. However, it is rare to find them in predominant neutrophilic bullous dermatoses such as linear immunoglobulin A. Read More

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http://dx.doi.org/10.1097/DAD.0000000000001690DOI Listing

A Review Comparing International Guidelines for the Management of Bullous Pemphigoid, Pemphigoid Gestationis, Mucous Membrane Pemphigoid, and Epidermolysis Bullosa Acquisita.

Am J Clin Dermatol 2020 Mar 16. Epub 2020 Mar 16.

Department of Dermatology, University of Illinois at Chicago, 808 S. Wood St, RM377, Chicago, IL, 60612, USA.

Autoimmune blistering disease management can be challenging as treatment modalities vary greatly and no single standard of care exists. We consolidated the recommendations of international management guidelines in order to provide optimal management suggestions to physicians. A comprehensive literature search in PubMed/MEDLINE for published blistering disease management guidelines and consensus statements was conducted in November 2019. Read More

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http://dx.doi.org/10.1007/s40257-020-00513-3DOI Listing

Dyshidrosiform Bullous Pemphigoid: Case Reports and Review.

Authors:
Philip R Cohen

Cureus 2020 Jan 11;12(1):e6630. Epub 2020 Jan 11.

Dermatology, San Diego Family Dermatology, San Diego, USA.

Bullous pemphigoid is an autoimmune blistering disorder that typically presents in elderly patients as pruritic tense subepidermal blisters on the lower trunk, axilla, and groin. It is caused by circulating and tissue-bound autoantibodies directed against bullous pemphigoid antigen 1 or bullous pemphigoid antigen 2 or both. Dyshidrosiform bullous pemphigoid is a rare variant of bullous pemphigoid, and it usually presents as itchy, potentially hemorrhagic, or purpuric blisters on the palms and/or soles of elderly individuals; subsequently, typical bullous lesions of bullous pemphigoid appear on other body sites. Read More

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http://dx.doi.org/10.7759/cureus.6630DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7008730PMC
January 2020

Pregnant Woman With Rash.

Ann Emerg Med 2020 02;75(2):306-314

Department of Osteopathic Medical Specialties, Michigan State University College of Osteopathic Medicine, East Lansing, MI; Sparrow Health System, Lansing, MI.

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http://dx.doi.org/10.1016/j.annemergmed.2019.08.421DOI Listing
February 2020
4.676 Impact Factor

[Pemphigoid gestationis after egg donation : A case report].

Authors:
E Oms M Tronnier

Hautarzt 2020 Mar;71(3):223-226

Dermatologie, Venerologie und Allergologie, Helios Klinikum Hildesheim, Senator-Braun-Allee 33, 31135, Hildesheim, Deutschland.

Pemphigoid gestationis (PG) is a blistering autoimmune skin disease, typically occurring in the second and third trimester of pregnancy. Aberrant expression of major histocompatibility complex (MHC) class II molecules on the chorionic villi seems to lead to antibody production against bullous pemphigoid (BP)-180. We report a case of PG in a woman whose pregnancy was achieved using egg donation. Read More

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http://dx.doi.org/10.1007/s00105-019-04518-wDOI Listing

Postpartum pruritic urticarial papules and plaques of pregnancy with blister formation resembling herpes gestationis.

Eur J Dermatol 2019 12;29(6):669-671

Department of Dermatology, Nara Medical University School of Medicine, 840 Shijo, Kashihara, Nara 634-8522.

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http://dx.doi.org/10.1684/ejd.2019.3669DOI Listing
December 2019

Targetoid form of polymorphic eruption of pregnancy: A case report.

SAGE Open Med Case Rep 2019 14;7:2050313X19882841. Epub 2019 Oct 14.

Division of Dermatology, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.

Polymorphic eruption of pregnancy, formerly known as pruritic and urticarial papules and plaques of pregnancy, is an uncommon cutaneous eruption that can affect women during their third trimester of pregnancy. As its name implies, it has a variety of morphologies and it is important to consider other diagnoses, such as pemphigoid gestationis, which polymorphic eruption of pregnancy can mimic. Sometimes, as in this case, polymorphic eruption of pregnancy can have a targetoid morphology reminiscent of erythema multiforme. Read More

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http://dx.doi.org/10.1177/2050313X19882841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792272PMC
October 2019

What is causing this pregnant patient's rash?

JAAPA 2019 10;32(10):54-56

In the PA program at MGH Institute of Health Professions in Boston, Mass., Joshua Merson is an assistant professor and Dominique Caruso Murphy is an instructor. The authors have disclosed no potential conflicts of interest, financial or otherwise.

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http://dx.doi.org/10.1097/01.JAA.0000580576.81378.d9DOI Listing
October 2019

Pemphigoid gestationis.

Med Clin (Barc) 2020 Apr 7;154(8):327. Epub 2019 Sep 7.

Departamento de Dermatología, Hospital Universitario de Valme, Ctra. de Cádiz, Km. 548,9, 41001 Sevilla, Spain.

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http://dx.doi.org/10.1016/j.medcli.2019.05.037DOI Listing

Lichen Planus Pemphigoides: From Lichenoid Inflammation to Autoantibody-Mediated Blistering.

Front Immunol 2019 2;10:1389. Epub 2019 Jul 2.

Department of Dermatology, University of Lübeck, Lübeck, Germany.

Lichen planus pemphigoides (LPP) is a very rare autoimmune sub-epidermal blistering disease associated with lichenoid skin changes. Initially thought to be a mere variant of more common inflammatory dermatoses, particularly Bullous Pemphigoid (BP) or Lichen Planus (LP), a growing body of evidence suggests that it is a disease entity in its own right. In common with a range of autoimmune blistering diseases, including BP, pemphigoid gestationis (PG), mucous membrane pemphigoid (MMP) and linear IgA dermatosis (LAD), a key feature of the disease is the development of autoantibodies against type XVII collagen (COL17). Read More

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http://dx.doi.org/10.3389/fimmu.2019.01389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614382PMC
July 2019
4 Reads

Pemphigoid variants affecting the skin.

Clin Exp Dermatol 2019 Oct 16;44(7):721-727. Epub 2019 May 16.

Department of Dermatology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.

Pemphigoid diseases are autoimmune subepidermal blistering diseases affecting the skin and mucous membranes, which are caused by autoantibodies targeting structural hemidesmosomal proteins or hemidesmosome-associated proteins. Variants of pemphigoid can be differentiated based on targeted antigens and clinical aspects. In this review, we will discuss pemphigoid variants that predominantly affect the skin, and provide clinicians with clues to diagnosis. Read More

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http://dx.doi.org/10.1111/ced.13984DOI Listing
October 2019
2 Reads

Review of autoimmune blistering diseases: the Pemphigoid diseases.

J Eur Acad Dermatol Venereol 2019 Sep 11;33(9):1685-1694. Epub 2019 Jul 11.

St George Hospital, Sydney, Australia.

Autoimmune Blistering Diseases of the Pemphigoid type is characterised by sub-epidermal blisters (SEB) with circulating autoantibodies against components of the basement membrane zone (BMZ). The main disorders to date include bullous pemphigoid (BP), pemphigoid gestationis, mucous membrane pemphigoid (MMP), epidermolysis bullosa acquisita (EBA), linear IgA disease (LABD), dermatitis herpetiformis (DH), lichen planus pemphigoides and bullous lupus. This is in contrast to pemphigus and related disorders, which demonstrate intraepidermal acantholysis and a positive Nikolsky sign. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jdv.15679
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http://dx.doi.org/10.1111/jdv.15679DOI Listing
September 2019
45 Reads

Successful treatment of one case of pemphigoid gestationis complicating with polycystic ovary syndrome.

Dermatol Ther 2019 05 25;32(3):e12898. Epub 2019 Apr 25.

Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, China.

Pemphigoid gestationis (PG) is a rare, autoimmune, subepidermal bullous dermatosis associated with pregnancy. It is mainly caused by autoantibodies against hemidesmosomal proteins-bullous pemphigoid 180, and usually presents in the second or third trimester of pregnancy sometimes exacerbates spontaneously after delivery. Here we reported a case of PG with polycystic ovary syndrome (PCOS). Read More

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http://dx.doi.org/10.1111/dth.12898DOI Listing
May 2019
26 Reads
1.478 Impact Factor

Treatment Update of Autoimmune Blistering Diseases.

Dermatol Clin 2019 Apr 14;37(2):215-228. Epub 2019 Feb 14.

Department of Medicine, University of Central Florida, Health Sciences Campus at Lake Nona, 2627 Northampton Avenue, Orlando, FL 32827-7408, USA. Electronic address:

The treatment of refractory autoimmune blistering diseases (AIBDs) has always been a challenge. Because randomized controlled trials are lacking, treatment has been based on analysis of anecdotal data. The last 2 decades has seen the use of rituximab become a conventional treatment in the therapeutic armamentarium of AIBDs, leading to its Food and Drug Administration indication for pemphigus vulgaris in 2018. Read More

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http://dx.doi.org/10.1016/j.det.2018.12.003DOI Listing
April 2019
10 Reads

Pemphigoid Gestationis.

Clin Pract Cases Emerg Med 2019 Feb 7;3(1):79-80. Epub 2019 Jan 7.

Maricopa Medical Center, Department of Emergency Medicine, Phoenix, Arizona.

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http://dx.doi.org/10.5811/cpcem.2018.11.39258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366384PMC
February 2019
4 Reads

Pemphigoid Gestationis Mimicking Erythema Multiforme With Mucosal Involvement.

Actas Dermosifiliogr 2019 Oct 4;110(8):696-697. Epub 2019 Feb 4.

Departamento de Dermatología, Hospital del Mar-Parc Salut Mar, Barcelona, España.

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http://dx.doi.org/10.1016/j.ad.2018.02.038DOI Listing
October 2019
5 Reads

Specific dermatoses of pregnancy other than pemphigoid gestationis.

G Ital Dermatol Venereol 2019 Jun 29;154(3):286-298. Epub 2018 Oct 29.

Section of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence, Italy.

Specific dermatoses of pregnancy are skin disorders that occur specifically during or immediately after pregnancy and cannot be found in non-pregnant patients. According to the current consensus, they include atopic eruption of pregnancy (AEP), polymorphic eruption of pregnancy (PEP), pemphigoid gestationis (PG), and intrahepatic cholestasis of pregnancy (ICP). The diagnosis of specific dermatoses of pregnancy can be challenging due to their variation in clinical presentation; moreover, the tests currently available do not always provide the clue for the diagnosis. Read More

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http://dx.doi.org/10.23736/S0392-0488.18.06159-XDOI Listing
June 2019
6 Reads

Autoimmune bullous diseases during pregnancy: insight into pathogenetic mechanisms and clinical features.

G Ital Dermatol Venereol 2019 Jun 29;154(3):256-262. Epub 2018 Oct 29.

Unit of Dermatology, Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy -

Pemphigoid gestationis (PG), also known as herpes gestationis, is the prototypic pregnancy-associated autoimmune bullous disease (AIBD), but also the other AIBDs, notably pemphigus vulgaris, may begin or exacerbate during pregnancy. Although the increase in concentration of T and B regulatory cells makes pregnancy a state of increased immunologic tolerance toward the semiallogeneic fetal antigens, a prevalent T helper (Th) 2 profile, that is reported to be associated with pregnancy, may cause exacerbation of pemphigus and AIBDs in general during this period. Active disease may lead to stillbirth, spontaneous abortion, preterm pregnancy, low birthweight, and neonatal pemphigus. Read More

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https://www.minervamedica.it/index2.php?show=R23Y9999N00A181
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http://dx.doi.org/10.23736/S0392-0488.18.06153-9DOI Listing
June 2019
17 Reads

Pemphigoid gestationis and intravenous immunoglobulin therapy.

Int J Womens Dermatol 2018 Sep 3;4(3):166-169. Epub 2018 May 3.

Department of Dermatology, St. George Hospital, Sydney, Australia.

Pemphigoid gestationis, which is also known as herpes gestationis, is a rare, pregnancy-associated, autoimmune bullous disease. Treatment depends on the severity of the disease for each patient and the safety and use of these drugs during pregnancy and breastfeeding must be taken into consideration to guide their use. We describe the therapeutic response of two cases of pemphigoid gestationis that did not respond to conventional immunosuppressive therapy or adverse effects limited their use. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S23526475183001
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http://dx.doi.org/10.1016/j.ijwd.2018.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116823PMC
September 2018
32 Reads

Pemphigoid gestationis.

Clin Case Rep 2018 Jul 7;6(7):1364-1365. Epub 2018 May 7.

1st Department of Obstetrics and Gynecology "Alexandra" General Hospital University of Athens Lourou str., P.O. 11528 Athens Greece.

Pemphigoid gestationis is a rare autoimmune skin disorder emerging exclusively during pregnancy. Topical and oral glucocorticoids as well as oral antihistamines are the standard medications administered during pregnancy, aiming to relieve pruritus and to suppress extensive blister formation. Obstetricians should be able to recognize and treat this rare clinical condition accordingly. Read More

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http://dx.doi.org/10.1002/ccr3.1545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028378PMC
July 2018
13 Reads

Pruritus in Pregnancy and Its Management.

Authors:
Mark A Bechtel

Dermatol Clin 2018 Jul 26;36(3):259-265. Epub 2018 Apr 26.

Division of Dermatology, Ohio State University College of Medicine, 540 Officenter Place, #240, Gahanna, OH 43230, USA. Electronic address:

Pruritus in pregnancy can be a source of significant discomfort in the pregnant patient. Some cases are associated with pregnancy-specific dermatoses, although some patients experience a flare of a preexisting dermatosis. Severe pruritus may be a manifestation of a pregnancy-specific dermatosis associated with increased fetal risks and complications. Read More

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http://dx.doi.org/10.1016/j.det.2018.02.012DOI Listing
July 2018
22 Reads

Phemphigoid gestationis.

BMJ Case Rep 2018 Jun 17;2018. Epub 2018 Jun 17.

Department of Gynecology/Obstetrics, Centro Hospitalar de Leiria, Leiria, Portugal.

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http://dx.doi.org/10.1136/bcr-2018-225242DOI Listing
June 2018
16 Reads

Pemphigoid gestationis with lethal fetal malformation and postpartum persistence.

J Dtsch Dermatol Ges 2018 Jun;16(6):775-777

Department of Dermatology, Allergology and Dermatosurgery, HELIOS University Medical Center Wuppertal, University of Witten/Herdecke, Germany.

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http://dx.doi.org/10.1111/ddg.13540DOI Listing
June 2018
9 Reads

Pemphigoid gestationis mit letaler fötaler Fehlbildung und postpartaler Persistenz.

J Dtsch Dermatol Ges 2018 Jun;16(6):775-777

Zentrum für Dermatologie, Allergologie und Dermatochirurgie, HELIOS Universitätsklinikum Wuppertal, Universität Witten/Herdecke.

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http://dx.doi.org/10.1111/ddg.13540_gDOI Listing
June 2018
10 Reads

Urticarial Lesions in a Pregnant Woman.

Acta Dermatovenerol Croat 2018 Apr;26(1):71-72

Sergio Santos-Alarcon, MD, Department of Dermatology, , Hospital Universitario Doctor Peset, Avinguda Gaspar Aguilar Nº 90, 4601 Valencia, Spain;

Dear Editor, Gestational pemphigoid (GP) is a rare autoimmune bullous dermatosis in pregnancy. GP usually occurs during the second or third month of pregnancy. It clinically manifests as the development of either early-onset urticarial lesions or late-onset subepidermal blisters that may linger for weeks or even months. Read More

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April 2018
36 Reads
0.581 Impact Factor

Histologic characterization of cellular infiltration in autoimmune subepidermal bullous diseases in a tertiary hospital in Saudi Arabia.

Clin Cosmet Investig Dermatol 2018 24;11:187-194. Epub 2018 Apr 24.

Department of Dermatology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Background: Autoimmune subepidermal bullous dermatoses have similar clinical features to those of a spectrum of immune reactants at the dermoepidermal junction (DEJ). It is difficult to obtain a precise diagnosis without an immunofluorescence assay because of their similar clinical presentations. The aim of this study was to describe the cellular cutaneous infiltration among autoimmune subepidermal bullous dermatoses. Read More

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https://www.dovepress.com/histologic-characterization-of-cel
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http://dx.doi.org/10.2147/CCID.S158388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927141PMC
April 2018
14 Reads

Pemphigoid gestationis successfully treated with intravenous immunoglobulin.

BMJ Case Rep 2018 Apr 7;2018. Epub 2018 Apr 7.

Department of Dermatovenereology, Hospital de Braga, Braga, Portugal.

Pemphigoid gestationis (PG), also known as , is a rare autoimmune blistering disease specific to pregnancy, which usually presents in the second or third trimesters and, in 15%-25% of cases, during the immediate postpartum period.Although the ethiopathogeny of PG is not fully clarified, most patients develop antibodies against a 180 kDa transmembrane hemidesmosomal protein (BP180; BPAG2; collagen XVII). PG has a strong association with human leucocyte antigens DR3 and DR4. Read More

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http://dx.doi.org/10.1136/bcr-2018-224346DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893973PMC
April 2018
7 Reads

Pemphigoid gestationis: a case series and review of the literature.

J Dermatolog Treat 2018 Dec 7;29(8):815-818. Epub 2018 May 7.

a Department of Dermatology , Wake Forest School of Medicine , Winston-Salem , NC , USA.

Pemphigoid gestationis (PG) is a rare autoimmune disease associated with pregnancy. Clinically, it presents with severe pruritus that precedes the appearance of vesiculobullous lesions. It usually begins on the trunk and spread rapidly to other parts of the body. Read More

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http://dx.doi.org/10.1080/09546634.2018.1459034DOI Listing
December 2018
18 Reads

Pemphigoid Gestationis: A Case Presentation.

J Cutan Med Surg 2018 Jul/Aug;22(4):435-438. Epub 2018 Feb 28.

1 Department of Obstetrics and Gynecology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1177/1203475418760459DOI Listing
December 2018
76 Reads

A subset of patients with pemphigoid (herpes) gestationis has serological evidence of celiac disease.

Int J Dermatol 2018 May 23;57(5):534-540. Epub 2018 Feb 23.

Immunodermatology Laboratory, Department of Dermatology, School of Medicine, University of Utah, Salt Lake City, UT, USA.

Background: Pemphigoid (herpes) gestationis (PG) is an uncommon, self-limited disease with other autoimmune associations; however, celiac disease (CD) is not recognized as one.

Methods: From 71 patients' sera submitted for herpes gestationis factor (HGF) testing over a 5-year period, 12 were consistent with PG demonstrating HGF and increased IgG BP180 antibody levels; these sera were tested for IgA and IgG endomysial antibodies (EMA), epithelial basement membrane zone and cell surface antibodies by indirect immunofluorescence, and for IgA and IgG tissue transglutaminase (transglutaminase 2 or TG2) antibodies, IgA epidermal transglutaminase (transglutaminase 3 or TG3) antibodies, IgG BP230, and IgG desmoglein 1 and desmoglein 3 antibodies by enzyme-linked immunosorbent assays (ELISAs).

Results: Three of 12 patients' sera with PG (25%) had CD antibodies with positive IgA EMA and increased IgA TG2 antibody levels; two of these had positive IgG EMA, and one other had an increased IgA TG3 antibody level. Read More

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http://dx.doi.org/10.1111/ijd.13925DOI Listing
May 2018
8 Reads

Treatment of Autoimmune Bullous Disorders in Pregnancy.

Am J Clin Dermatol 2018 Jun;19(3):391-403

Corporal Michael J. Crescenz VAMC, Philadelphia, PA, USA.

Autoimmune bullous diseases (AIBD), including pemphigus, bullous pemphigoid, epidermolysis bullosa acquisita, mucous membrane pemphigoid, and pemphigoid gestationis, pose significant therapeutic challenges, especially in pregnant and post-partum breastfeeding patients or those planning to conceive. Data on the safety and efficacy of therapeutic interventions during the perinatal period are lacking because randomized controlled trials are typically not performed in this setting. However, many of the treatments for AIBD are also used in other diseases, so data can be extrapolated from studies or case reports in these other patient populations. Read More

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http://dx.doi.org/10.1007/s40257-018-0342-0DOI Listing
June 2018
24 Reads

Anhydramnios in Patients With Pemphigoid Gestationis.

JAMA Dermatol 2018 04;154(4):484-486

Department of Obstetrics and Gynecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

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http://dx.doi.org/10.1001/jamadermatol.2017.5539DOI Listing
April 2018
14 Reads

Spectrum of Autoimmune Bullous Diseases in Northern Greece. A 4-year Retrospective Study and Review of the Literature.

Acta Dermatovenerol Croat 2017 Oct;25(3):195-201

Foteini Lamprou, MD, MSc, PhD candidate, 2nd University Department of Dermatology Papageorgiou General Hospital Aristotle University of Thessaloniki, Ring Road, Municipality of Pavlos Melas, Area of N. Efkarpia, 56403 Thessaloniki, Greece;

Bullous Diseases Unit at the 2nd Department of Dermatology and Venereology, Aristotle University of Thessaloniki was founded with the aim to provide the optimal diagnostic approach and treatment of patients with autoimmune bullous diseases (AΙBD). We processed all AIBD files of patients diagnosed from 2011 to 2014 in order to record all epidemiological data and therapeutic manipulations during monitoring. 57 patients were diagnosed with intraepidermal and 62 with subepidermal bullous diseases. Read More

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October 2017
27 Reads

Case of epidermolysis bullosa acquisita with concomitant anti-laminin-332 antibodies.

J Dermatol 2018 Apr 4;45(4):472-474. Epub 2017 Dec 4.

Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Subepidermal autoimmune blistering disease including bullous pemphigoid, pemphigoid gestationis, mucous membrane pemphigoid, anti-laminin-γ1 pemphigoid, linear immunoglobulin A bullous disease and epidermolysis bullosa acquisita (EBA), are all characterized by direct immunofluorescence microscopy or immunoglobulin deposition on the basement membrane zone. Among them, EBA is a rare acquired subepidermal autoimmune blistering disease of the skin and mucous membranes reactive with type VII collagen, a major component of the epidermal basement membrane zone. Anti-laminin-332-type mucous membrane pemphigoid has pathogenic autoantibodies against laminin-332, which is a basement membrane heterotrimeric protein composed of α3, β3 and γ2 laminin chains. Read More

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http://dx.doi.org/10.1111/1346-8138.14169DOI Listing
April 2018
21 Reads

Pemphigoid gestationis: current perspectives.

Clin Cosmet Investig Dermatol 2017 8;10:441-449. Epub 2017 Nov 8.

Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark.

Many skin diseases can occur in pregnant women. However, a few pruritic dermatological conditions are unique to pregnancy, including pemphigoid gestationis (PG). As PG is associated with severe morbidity for pregnant women and carries fetal risks, it is important for the clinician to quickly recognize this disease and refer it for dermatological evaluation and treatment. Read More

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http://dx.doi.org/10.2147/CCID.S128144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5685197PMC
November 2017
8 Reads

Subepidermal autoimmune bullous diseases: overview, epidemiology, and associations.

Authors:
Khalaf Kridin

Immunol Res 2018 02;66(1):6-17

Department of Dermatology, Rambam Health Care Campus, POB 9602, 31096, Haifa, Israel.

Subepidermal autoimmune bullous diseases of the skin and mucosae comprise a large group of chronic diseases, including bullous pemphigoid, pemphigoid gestationis, mucous membrane pemphigoid, linear IgA bullous dermatosis, epidermolysis bullosa acquisita, and anti-p200 pemphigoid. These diseases are characterized by an antibody response toward structural components of the basement membrane zone, resulting in subepidermal blistering. The epidemiological features of these diseases vary substantially in different regions of the world. Read More

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http://dx.doi.org/10.1007/s12026-017-8975-2DOI Listing
February 2018
63 Reads

The Value of Direct Immunofluorescence on Proteinase-Digested Formalin-Fixed Paraffin-Embedded Skin Biopsies.

Am J Dermatopathol 2018 Feb;40(2):111-117

Department of Pathology, University of Massachusetts Medical School, UMass Memorial Medical Center, Worcester, MA.

Direct immunofluorescence (DIF) on frozen tissue (DIF-F) is the method of choice for the identification of immune deposits present in skin and other tissues. DIF can also be performed on formalin-fixed paraffin-embedded tissue (DIF-P) after antigen retrieval with proteases and has proven to be of value in renal pathology. However, its utility in skin biopsies has not been fully examined. Read More

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http://dx.doi.org/10.1097/DAD.0000000000000934DOI Listing
February 2018
41 Reads

Autoimmune Subepidermal Bullous Diseases of the Skin and Mucosae: Clinical Features, Diagnosis, and Management.

Clin Rev Allergy Immunol 2018 Feb;54(1):26-51

Department of Dermatology, University of Bern, Bern, Switzerland.

Autoimmune subepidermal blistering diseases of the skin and mucosae constitute a large group of sometimes devastating diseases, encompassing bullous pemphigoid, gestational pemphigoid, mucous membrane pemphigoid, epidermolysis bullosa acquisita, and anti-p200 pemphigoid. Their clinical presentation is polymorphic. These autoimmune blistering diseases are associated with autoantibodies that target distinct components of the basement membrane zone of stratified epithelia. Read More

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http://dx.doi.org/10.1007/s12016-017-8633-4DOI Listing
February 2018
25 Reads

Herpes gestationis and oral contraceptive: Case report and review of the literature.

Dermatol Ther 2017 09 21;30(5). Epub 2017 Jul 21.

Dermatology Department, Policlinico Universitario "A. Gemelli", Università Cattolica del Sacro Cuore, Rome, Italy.

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http://dx.doi.org/10.1111/dth.12518DOI Listing
September 2017
6 Reads

Pemphigoid gestationis: Clinical and histologic features of twenty-three patients.

Int J Womens Dermatol 2017 Jun 23;3(2):86-90. Epub 2016 Dec 23.

Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

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http://dx.doi.org/10.1016/j.ijwd.2016.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440447PMC
June 2017
8 Reads

Severe pemphigoid gestationis associated with acute disseminated encephalomyelitis in the setting of a systemic disorder.

Australas J Dermatol 2018 May 19;59(2):e123-e126. Epub 2017 May 19.

Department of Neurology, Mohammed V. Rabat Military Hospital, Rabat, Morocco.

Pemphigoid gestationis is a skin-specific autoimmune disorder that can sometimes present as the cutaneous manifestation of a multiorgan disease due to potentially common pathogenic mechanisms. We report a severe form of pemphigoid gestationis in a 32-year-old primigravida woman, who presented at 22 weeks of gestation with headaches and blurred vision, later developing encephalitis, intrauterine fetal demise and dilated cardiomyopathy. Read More

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http://doi.wiley.com/10.1111/ajd.12656
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http://dx.doi.org/10.1111/ajd.12656DOI Listing
May 2018
85 Reads

Image Gallery: Pemphigoid gestationis mimicking a gyrate erythema.

Authors:
C H Nam S P Hong

Br J Dermatol 2017 04;176(4):e36

Department of Dermatology, Dankook University College of Medicine, San 16-5, Anseo dong, Cheonan, Chungnam, Republic of Korea.

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http://dx.doi.org/10.1111/bjd.15325DOI Listing
April 2017
4 Reads

Pruritic Rash in Pregnancy.

Am Fam Physician 2017 Apr;95(7):453-454

Thomas Jefferson University Hospital, Philadelphia, PA, USA.

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April 2017
5 Reads

Early flare-up of severe Herpes gestationis (Pemphigoid gestationis) and successfull prolonged treatment: A case report.

J Obstet Gynaecol 2017 Aug 11;37(6):824-826. Epub 2017 Apr 11.

a Department of Obstetrics and Gynecology , University Hospital Martin and Jessenius Faculty of Medicine, Comenius University , Martin , Slovakia.

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https://www.tandfonline.com/doi/full/10.1080/01443615.2017.1
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http://dx.doi.org/10.1080/01443615.2017.1305334DOI Listing
August 2017
15 Reads

[Skin and pregnancy].

Rev Prat 2017 04;67(4):411-414

Service de dermatologie, hôpital Cochin- Tarnier, faculté de médecine Paris-Descartes, Paris, France.

Skin and pregnancy. Skin manifestations during pregnancy are common and diversified. Physiological changes are the most frequently reported. Read More

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April 2017
11 Reads

A postpartum eruption.

BMJ 2017 03 9;356:j968. Epub 2017 Mar 9.

Tunbridge Wells Hospital, Tunbridge Wells, UK.

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http://dx.doi.org/10.1136/bmj.j968DOI Listing
March 2017
6 Reads

A resistant case of pemphigus gestationis successfully treated with cyclosporine.

Interv Med Appl Sci 2016 Mar;8(1):20-22

Department of Obstetrics and Gynecology, Ankara Numune Education and Research Hospital , Ankara , Turkey.

Pemphigoid gestationis (PG) is a rare autoimmune blistering disease of pregnancy caused by antibasement membrane zone auto-antibodies. The usual clinical findings are multiple pruritic urticarial papules and plaques, target lesions, vesicles, and blisters that occur during the second and third trimesters of pregnancy or in the immediate postpartum period. The disease is often treated with topical corticosteroids and oral antihistaminics. Read More

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http://dx.doi.org/10.1556/1646.8.2016.1.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322493PMC
March 2016
10 Reads

Sensitivity and specificity of BP180 NC16A enzyme-linked immunosorbent assay for the diagnosis of pemphigoid gestationis.

J Am Acad Dermatol 2017 Mar;76(3):560-562

Department of Dermatology, INSERM U1234, Rouen University Hospital, University of Rouen, France. Electronic address:

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http://dx.doi.org/10.1016/j.jaad.2016.09.030DOI Listing
March 2017
63 Reads