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Int Urogynecol J 2021 May 15. Epub 2021 May 15.

Department of Obstetrics and Gynecology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Introduction And Hypothesis: Evidence and recommendations for the use of intravaginal estrogen for prevention of bacterial vaginosis and pessary-related complications are limited and controversial. We hypothesized that adding intravaginal estrogen to pessary use would decrease the incidence of bacterial vaginosis and other pessary-related complications.

Methods: A single-center, open-label, randomized, parallel study was conducted between April 2018 and August 2020. Read More

Int Urogynecol J 2021 May 15. Epub 2021 May 15.

Department of Obstetrics and Gynaecology, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Mas Casanovas, 90, 08025, Barcelona, Spain.

Introduction And Hypothesis: Pelvic floor dysfunction (PFD) is common in women but few seek medical attention. Poor recognition of the condition as pathological and unawareness of treatments may account for low consultation rates.

Methods: This cross-sectional study was based on an online survey that was responded to in February and March 2020 by 768 female university students. Read More

Int Urogynecol J 2021 May 14. Epub 2021 May 14.

St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.

Int Urogynecol J 2021 May 14. Epub 2021 May 14.

Department of Obstetrics and Gynecology, Albany Medical Center, Albany, NY, USA.

Introduction And Hypothesis: This was a planned secondary analysis of a systematic review that described sexual function outcomes following pelvic organ prolapse (POP) surgery. We aimed to describe the relationship of pre- and postoperative vaginal anatomic measures with sexual function outcomes. Data Sources included the Medline, Embase, and clinicaltrials. Read More

BMJ Case Rep 2021 May 13;14(5). Epub 2021 May 13.

Obstetrics & Gynaecology, Mid Cheshire Hospitals NHS Foundation Trust, Crewe, Cheshire, UK.

We describe the first reported case of transient distal ureteric obstruction attributed to post-surgical oedema in a patient with a solitary kidney. This occurred following combined pelvic floor repair and sacrospinous fixation for recurrent pelvic organ prolapse and manifested clinically as anuria, radiological hydroureter and acute kidney injury in the postoperative period. The transient nature of this obstruction, which was managed by a temporary percutaneous nephrostomy, indicates that it was caused by ureteric compression secondary to soft tissue oedema following surgery. Read More

J Obstet Gynaecol Can 2021 May 10. Epub 2021 May 10.

Mount Sinai Hospital, 700 University Avenue, 8-816 Toronto, Ontario, M5G 1Z5. Electronic address:

Objective: The incidence of post-hysterectomy vault prolapse following native tissue repair has been reported to be as high as 43%. The optimal way to maintain vault support is unknown. Our aim was to evaluate the long-term efficacy of modified McCall culdoplasty during vaginal hysterectomy for symptomatic uterine prolapse in preventing the recurrence of vaginal vault prolapse. Read More

Am J Obstet Gynecol 2021 May 10. Epub 2021 May 10.

Department of Obstetrics, Gynecology & Reproductive Science, University of California San.

Background: There is limited literature identifying racial and ethnic health disparities among surgical modalities and outcomes in the field of urogynecology and specifically pelvic organ prolapse surgery.

Objective: To evaluate differences in surgical approach for apical vaginal prolapse and postoperative complications by race and ethnicity STUDY DESIGN: This is a retrospective cohort study of women undergoing surgical repair for apical vaginal prolapse between 2014 and 2017 using data from the American College of Surgeons National Surgical Quality Improvement Program. Patients were eligible for inclusion if they underwent either a vaginal colpopexy or abdominal sacrocolpopexy (ASC). Read More

J Am Geriatr Soc 2021 May 12. Epub 2021 May 12.

Urogynecology and Pelvic Floor Unit, Department of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

Objectives: To present a flexible protocol of vaginal pessaries for older women with significant pelvic organ prolapse (POP).

Design: A prospective cohort study of 140 consecutive older women (aged ≥65 years) with significant POP treated with individually fitted vaginal pessaries. After initial insertion, each patient was invited for a first evaluation after 1 month and subsequent follow-ups at increasing intervals of 1 month. Read More

BMC Womens Health 2021 May 11;21(1):195. Epub 2021 May 11.

Section of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynaeacology, Foothills Medical Centre, School of Medicine, University of Calgary, 1403 29 Street Northwest, Calgary, AB, T2N 2T9, Canada.

Purpose: Transient postoperative urinary retention (POUR) is common after pelvic floor surgery. We aimed to determine the association between peri-operative variables and POUR and to determine the number of voids required for post-void residuals (PVRs) to normalize postoperatively.

Methods: We conducted a retrospective cohort study of 992 patients undergoing pelvic floor surgery at a tertiary referral centre from January 2015 to October 2017. Read More

Int Urogynecol J 2021 May 11. Epub 2021 May 11.

Department of Pediatrics, Gynecology and Obstetrics, Division of Gynecology, Urogynecology Unit, Geneva University Hospitals, 30 boulevard de la Cluse, 1211, Genève 14, Switzerland.

Introduction And Hypothesis: The objective of our study was to describe the distribution of pelvic organ prolapse (POP) in a population of women undergoing POP reconstructive surgery and to identify compartment-specific risk factors.

Methods: We conducted a retrospective observational study in a cohort of 326 women who underwent POP repair and had a standardized preoperative POP assessment using the Baden-Walker classification. The distribution of POP grade was described for each vaginal compartment. Read More

J Orthop Sports Phys Ther 2021 May 10:1-54. Epub 2021 May 10.

Department of Physiotherapy, Monash University, Melbourne, Australia.

Objective: To (i) review the effect of pelvic floor (PF) symptoms (urinary incontinence [UI], pelvic organ prolapse [POP], anal incontinence [AI]) on exercise participation in women, and (ii) explore PF symptoms as a barrier to exercising.

Design: Mixed-methods systematic review with meta-analysis.

Literature Search: Eight databases systematically searched to September 2020. Read More

Taiwan J Obstet Gynecol 2021 May;60(3):513-516

Department of Medicine, Mackay Medical College, New Taipei, 252, Taiwan; Division of Urogynecology, Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, 104, Taiwan; Department of Nursing, Mackay Junior College of Medicine, Nursing, and Management, Taipei, Taiwan. Electronic address:

Objective: Lower urinary tract symptoms (LUTS) are common in women. However, due to multifactorial etiologies, it is difficult to determine the prevalence, and functional changes with age. The aim of this study is to assess the effect of age on female LUTS, urethral and bladder function after their midlife. Read More

J Minim Invasive Gynecol 2021 May 4. Epub 2021 May 4.

Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, UCLA Medical Center, Los Angeles, CA.

Surgical approach to pelvic organ prolapse (POP) has traditionally included hysterectomy; however, in the past decade, uterine sparing prolapse surgery (hysteropexy) has become increasingly popular within female pelvic medicine and reconstructive surgery. The current literature demonstrates comparable outcomes for hysteropexy and traditional approach. As these procedures become more common, it is important to consider how to approach patients with unique anatomy such as uterine anomalies who desire uterine sparing surgery. Read More

Urologiia 2021 May(2):94-99

Institute of Chemical Biology and Fundamental Medicine, The Russian Academy of Sciences, Siberian Branch, Novosibirsk, Russia.

Based on the literary analysis, the influence of cellular technologies on the results of implantation of mesh materials was studied. The scientific literature of recent years contains a large amount of data devoted to the study of mesh structures and the possibilities of their modification using multipotent stromal cells (MSC) for implantation into patients for correcting tissue defects and pelvic organ prolapse. However, the ideal implant has not yet been created. Read More

Obstet Gynecol 2021 May 4. Epub 2021 May 4.

Department of Obstetrics and Gynecology, McGill University, and St. Mary's Research Centre, Montreal, Québec, and the Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada.

Objective: To systematically review objective and subjective success and complications of apical suspensions for symptomatic uterine or vaginal vault pelvic organ prolapse (POP).

Data Sources: MEDLINE, CENTRAL, ClinicalTrials.gov, and EMBASE (2002-2019) were searched using multiple terms for apical POP surgeries, including comparative studies in French and English. Read More

J Urol 2021 May 6:101097JU0000000000001830. Epub 2021 May 6.

Department of Women's Health, Monash Medical Centre and Cabrini Hospital, Melbourne, Australia.

Purpose: Limited data exist regarding sexual function after single incision sling surgery. We compared sexual function 36 months postoperatively between patients undergoing single incision and transobturatorsling for treatment of stress urinary incontinence.

Materials And Methods: Assessment of sexual function was a planned secondary objective of this prospective, multi-center study that enrolled women to Solyx single incision sling or Obtryx II transobturator sling. Read More

Neurourol Urodyn 2021 May 5. Epub 2021 May 5.

Department of Obstetrics and Gynecology, Amsterdam Reproduction and Development, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Aim: Before the introduction of new biomaterials for prolapse surgery, animal studies on the host response are required. Unfortunately, large variation in study design hampers obtaining an overview of the safety and efficacy, and translation to clinical practice. Our aim is to systematically review the literature on all outcome measures describing the host response in animal studies assessing the biocompatibility of urogynecologic surgical mesh implants for prolapse surgery. Read More

Colorectal Dis 2021 May 4. Epub 2021 May 4.

Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston.

Introduction: Faecal incontinence (FI) is estimated to affect 8.9% of women in the US, with a significant impact on quality of life. Our aim was to compare urinary symptoms in patients with and without FI with different degrees of severity. Read More

J Obstet Gynaecol Res 2021 May 4. Epub 2021 May 4.

Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Osaka, Japan.

Aim: Tension-free vaginal mesh (TVM) surgery using synthetic polypropylene (PP) soft mesh had spread rapidly. However, the frequency of mesh-related postoperative complications had increased, and PP was banned in April 2019. In Japan, however, transvaginal surgery using polytetrafluoroethylene (PTFE) mesh had been approved. Read More

Int Urogynecol J 2021 May 4. Epub 2021 May 4.

University of Sydney, Penrith, NSW, Australia.

Introduction And Hypothesis: The primary aim of this study was to assess for an association between maximal intra-abdominal pressure reached on Valsalva (MAP) and pelvic organ prolapse (POP) on subjective, clinical and sonographic evaluation. Another objective was to test for association between MAP and body mass index (BMI).

Methods: A retrospective cross-sectional study was carried out on 504 archived datasets of women seen for pelvic floor dysfunction symptoms between January 2017 to September 2019 at a tertiary urogynaecology clinic. Read More

J Menopausal Med 2021 Apr;27(1):32-36

Department of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Müllerian development anomalies (MDAs) are most commonly diagnosed in the reproductive period. A bicornuate uterus is the result of a fusion defect of the Müllerian ducts, causing an abnormal fundal outline. Most of the cases are diagnosed early in life and present with obstetrical complications, such as recurrent pregnancy loss, preterm birth, intrauterine growth restriction, placental abruption, and cervical incompetence. Read More

Urologe A 2021 May 3. Epub 2021 May 3.

Klinik und Poliklinik für Urologie, LMU Klinikum, Campus Großhadern, München, Deutschland.

Surgery for urinary incontinence is indicated after failure of conservative treatment with pelvic floor therapy. Different sling systems are the established treatment option for urinary incontinence for female and male patients. Tension-free vaginal tapes represent the standard of care in the surgical treatment of female stress urinary incontinence. Read More

Int Urogynecol J 2021 May 3. Epub 2021 May 3.

Faculty of Medicine, School of Health Sciences, University of Iceland, Vatnsmýrarvegi 16, 101, Reykjavík, Iceland.

Introduction And Hypothesis: To study the prevalence of pelvic floor dysfunction and related bother in primiparous women 6-10 weeks postpartum, comparing vaginal and cesarean delivery.

Methods: Cross-sectional study of 721 mothers with singleton births in Reykjavik, Iceland, 2015 to 2017, using an electronic questionnaire. Information on urinary and anal incontinence, pelvic organ prolapse and sexual dysfunction with related bother (trouble, nuisance, worry, annoyance) was collected. Read More

Int Urogynecol J 2021 May 3. Epub 2021 May 3.

Department of Gynecology and Obstetrics, Emory University School of Medicine, Emory Gyn/Ob Clinic, 1365 Clifton Road, Bldg A, 4th Floor, Attention Daphne Blow, Atlanta, GA, 30322, USA.

Introduction And Hypothesis: We hypothesized obesity increases the risk of pelvic organ prolapse recurrence (POP-R) after primary apical prolapse repair.

Methods: We conducted a retrospective cohort study of 353 women who underwent primary apical prolapse surgery from 2011 to 2016. Demographic and clinical data were abstracted from medical records. Read More

Prz Menopauzalny 2021 Apr 15;20(1):21-28. Epub 2021 Mar 15.

Department of Obstetrics and Gynecology, Ain Shams University, Cairo, Egypt.

Introduction: To evaluate the surgical outcome, and quality of life (QoL) 12-months after Le Fort colpocleisis (LFC), and sacrospinous fixation (SSF) in older postmenopausal women.

Material And Methods: Eighty-six (86) post-menopausal women were included in this study (38 in the LFC group and 48 in the SSF group). Pelvic organ prolapse quantification (POP-Q) was used to evaluate the participants' pelvic organ prolapse (POP) pre-operatively and post-operatively (PO). Read More

J Obstet Gynaecol Can 2021 Apr 29. Epub 2021 Apr 29.

Sherbrooke University Hospital: Centre integre universitaire de sante et de services sociaux de l'Estrie Centre hospitalier universitaire de Sherbrooke du Quebec.

Objective: Many women with pelvic organ prolapse opt for a pessary, and some of these women develop erosions of the vaginal mucosa. Ongoing erosions might lead to the discontinuation of this otherwise effective, non-invasive, and inexpensive treatment. The objectives of this study were to investigate the differences in vaginal pH and variations of the vaginal microbiota among pessary and non-pessary users. Read More

PLoS One 2021 30;16(4):e0250943. Epub 2021 Apr 30.

Department of Obstetrics and Gynecology, Seventh Medical Center, Chinese PLA General Hospital, Beijing, People's Republic of China.

Background: The collagen 3 alpha 1 (COL3A1) rs1800255 polymorphism has been reported to be associated with women pelvic organ prolapse (POP) susceptibility, but the results of these previous studies have been contradictory. The objective of current study is to explore whether COL3A1 rs1800255 polymorphism confers risk to POP.

Methods: Relevant literatures were searched by searching databases including Pubmed, Embase, Google academic, the Cochrane library, China National Knowledge Infrastructure (CNKI). Read More

Wien Klin Wochenschr 2021 Apr 30. Epub 2021 Apr 30.

Department of General Gynecology and Gynecologic Oncology, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria.

Objective: To define potential risk factors for recurrence of prolapse.

Methods: This short report included all women who presented with recurrence of prolapse as well as without any recurrence signs after a vaginal approach of native tissue prolapse repair at an urogynecological center in Austria.

Results: A total of 124 recurrence cases and 64 women with no signs of recurrence after their index prolapse surgery were included. Read More

J Clin Med 2021 Apr 27;10(9). Epub 2021 Apr 27.

School of Medicine, Tzu Chi University, Hualien 970, Taiwan.

The aim of this study was to compare the clinical outcomes of transvaginal mesh (TVM) surgery with and without midline fascial plication for anterior prolapse repair. This is a prospective randomized trial in a teaching hospital. This study compared patients with anterior vaginal wall prolapse (POP-Q Ba > -1) who were randomly assigned to either transvaginal mesh (TVM, Avaulta Solo, CR Bard. Read More

J Clin Med 2021 Apr 13;10(8). Epub 2021 Apr 13.

Department of Public and Maternal and Child Health, School of Medicine, Complutense University of Madrid, 28040 Madrid, Spain.

Objective: To compare pelvic floor disorders between vaginal delivery (VD) and cesarean delivery (CD).

Methods: For this study, a PUBMED database search was used, utilizing a combination of relevant medical subjects' headings (MeSH) terms, with the following keywords: "Pelvic floor disorders" or "Pelvic floor morbidity" and "Delivery". Search limits were articles in English or Spanish, about women, published from December 2009 to December 2019. Read More