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Surg Today 2020 Jun 1. Epub 2020 Jun 1.

Division of Surgical Oncology, Department of Surgery, Nagoya Graduate School of Medicine, Nagoya, Japan.

Purpose: This study aimed to clarify the long-term change in the renal function after pelvic exenteration (PE) and to evaluate the risk factors for any future dysfunction.

Methods: This study comprised 40 patients. A greater than 25% decline in the estimated glomerular filtration rate (eGFR) at 3 years was defined as early renal function disorder (ERFD), possibly predicting future chronic kidney disease (CKD). Read More

Front Oncol 2020 13;10:719. Epub 2020 May 13.

Department of Plastic and Hand Surgery, University Hospital Erlangen-Friedrich Alexander University of Erlangen-Nuernberg FAU, Erlangen, Germany.

Relapsing or far advanced rectal and anal cancers remain difficult to treat and require interdisciplinary approaches. Due to modern standard protocols all patients receive irradiation and neoadjuvant chemotherapy-and in case of a relapse a second irradiation-rendering the surgical site prone to surgical site infections and oftentimes long lasting sinus and septic complications after exenteration in the pelvis. Despite an improved overall survival rate in these patients the downside of radical tumor surgery in the pelvis is a major loss of quality of life, especially in women when parts of the vagina need to be resected. Read More

Gynecol Oncol Rep 2020 Aug 16;33:100585. Epub 2020 May 16.

University of Cincinnati Department of Obstetrics & Gynecology: Division of Gynecologic Oncology, 234 Goodman Street, Cincinnati, OH 45219, USA.

Primary vaginal endometrioid adenocarcinoma is a rare cancer that is often associated with chronic endometriosis. We present the case of a 72-year-old female who underwent right salpingo-oophorectomy followed by hysterectomy with benign pathology 25 years prior to her cancer diagnosis. She had an extensive surgical history in the intervening years and several complicating factors including a history of endometriosis as well as a recurrent peritoneal inclusion cyst treated with ethanol sclerotherapy, followed by formation of a peritoneal-vaginal fistula. Read More

Semin Ultrasound CT MR 2020 Apr 24;41(2):183-206. Epub 2020 Jan 24.

Department of Radiology and Orthopedics, University of Arkansas for Medical Sciences, Little Rock, AR.

High-resolution phased array external magnetic resonance imaging (MRI) is the first investigation of choice in rectal cancer for local staging, both in the primary and restaging situations. Use of MRI helps differentiate between those with good prognosis, which can be offered upfront surgery and the poor prognostic cases where treatment intensification is needed. MRI identified poor prognostic factors are threatened or involved mesorectal fascia, T3 tumors with >5 mm extramural spread, those with extramural vascular invasion, pelvic sidewall nodes and mucinous tumors. Read More

Plast Reconstr Surg Glob Open 2020 Apr 24;8(4):e2733. Epub 2020 Apr 24.

Division of Plastic and Reconstructive Surgery, Stanford University Medical Center, Palo Alto, Calif.

Background: Abdominoperineal resection (APR) and pelvic exenteration continue to be common procedures for the treatment of colorectal malignancy. The workhorse flap for reconstruction in these instances has been the vertical rectus abdominis myocutaneous flap. The associated donor site morbidity, however, cannot be ignored. Read More

World J Gastrointest Surg 2020 Apr;12(4):190-196

Department of General Surgery, Tan Tock Seng Hospital, Singapore 308433, Singapore.

Background: Pelvic exenteration for locally advanced rectal cancer involving prostate has been performed open surgery. Robotic pelvic exenteration offers benefits of better pelvic visualisation and dissection for bladder preserving prostatectomy with vesicourethral anastomosis, while achieving clear margins.

Aim: To determine the feasibility of robotic assisted bladder sparing pelvic exenteration. Read More

J Surg Oncol 2020 May 18. Epub 2020 May 18.

Colorectal Surgery Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Background And Objectives: Selection of patients affected by pelvic recurrence of rectal cancer (PRRC) who are likely to achieve a R0 resection is mandatory. The aim of this study was to propose a classification for PRRC to predict both radical surgery and disease-free survival (DFS).

Methods: PRRC patients treated at the National Cancer Institute of Milan (Italy) were included in the study. Read More

J Minim Invasive Gynecol 2020 May 8. Epub 2020 May 8.

Department of Medical and Surgical Gynecology (Drs. Haverland and Yi).

Study Objective: To analyze outcomes and postoperative complications in patients undergoing robot-assisted rectus abdominis flap harvest for pelvic floor reconstruction.

Design: Case series.

Setting: Academic setting. Read More

Gan To Kagaku Ryoho 2020 Feb;47(2):352-354

Dept. of Gastrointestinal Surgery, Kansai Medical University Medical Center.

A 70-year-old man underwent a colonoscopy and enhanced CT for scrutiny of his anemia. These examinations revealed rectal cancer(cT4b[rectal mesenteric infiltration], N3M0, cStage Ⅲc). We introduced neoadjuvant chemotherapy(NAC) (cetuximab plus oxaliplatin plus S-1, 4 courses)for this patient and diagnosed ycStage Ⅲc(ycT4bN3M0)after the therapy. Read More

Zhonghua Fu Chan Ke Za Zhi 2020 Apr;55(4):259-265

Department of Gastroenterological Surgery, Peking University People's Hospital, Beijing 100044, China.

To investigate the perioperative situation and recent effect of pelvic exenteration for patients with locally recurrent cervical cancer. A total of 17 patients with locally recurrent cervical cancer who underwent pelvic exenteration in Peking University People's Hospital from October 2015 to May 2018 were retrospectively analyzed for their clinical and pathological characteristics, surgical conditions, hospitalization costs, postoperative complications, and survival situation. (1) The median age of 17 patients with locally recurrent cervical cancer was 51 years (range 27-64 years). Read More

Ann Surg Oncol 2020 May 4. Epub 2020 May 4.

Department of Surgical Oncology, Roswell Park Comprehensive Cancer Center, Clinical Sciences Center P-645, Buffalo, NY, USA.

Colorectal Dis 2020 May;22(5):484

Asian J Endosc Surg 2020 Apr 28. Epub 2020 Apr 28.

Department of Colorectal Surgery, Saku Central Hospital Advanced Care Center, Saku, Japan.

A 58-year-old man had rectal cancer directly invading the urinary bladder and small intestine, without distant metastasis. We successfully performed complete resection using a hybrid approach, including laparoscopic surgery and transanal total pelvic exenteration (TaTPE) with the patient in the prone jackknife (PJK) position. In the PJK position, gravity and pelvic morphology lead to a clear and wide surgical field. Read More

BJU Int 2020 Apr 22. Epub 2020 Apr 22.

Department of Urology, Uro-Oncology, Robot-Assisted and Specialized Urological Surgery, University Hospital Cologne, Cologne, Germany.

Objectives: To evaluate retrospectively the surgical, symptomatic and oncological outcomes of pelvic exenteration surgery (PES) in men with significant intrapelvic complications of locally advanced castration-sensitive (CSPC) and castration-resistant prostate cancer (CRPC).

Patients And Methods: A total of 103 patients with locally advanced progressive and symptomatic CSPC or CRPC underwent PES (radical cystoprostatectomy, n = 71 [68.9%]; radical prostatectomy with continent vesicostomy, n = 9 [8. Read More

BMJ Case Rep 2020 Apr 16;13(4). Epub 2020 Apr 16.

Department of Surgery, Tallaght University Hospital, Dublin, Ireland.

A 62-year-old man presented to our institute with diarrhoea and dysuria on a background of subtotal colectomy and end ileostomy and biological therapy for Crohn's disease. He was diagnosed with urinary tract infection and acute kidney injury (AKI). Renal ultrasound suggested left hydronephrosis, with renal protocol computed tomography (CT) showing a large pelvic mass. Read More

Colorectal Dis 2020 Apr 15. Epub 2020 Apr 15.

Aim: At presentation, 15-20% of patients with rectal cancer already have synchronous liver metastases. The aim of this study was to determine the surgical and survival outcomes in patients with advanced rectal cancer who underwent combined pelvic exenteration and liver (oligometastatic) resection.

Method: Data from 20 international institutions that performed simultaneous pelvic exenteration and liver resection between 2007 and 2017 were accumulated. Read More

Gynecol Oncol Rep 2020 May 3;32:100567. Epub 2020 Apr 3.

Division of Gynecologic Oncology, University of Toronto, Odette Cancer Centre, Toronto, Canada.

To review the indications, technique and results of the rectus abdominis myoperitoneal (RAMP) flap for vaginal reconstruction from literature and at a single institution. A literature search was conducted of vaginal reconstruction to identify published cases using RAMP flaps. All cases of vaginal reconstruction at Sunnybrook Health Sciences Center (SHSC) from 2007 to 2019 were reviewed. Read More

Asian J Urol 2020 Apr 5;7(2):181-185. Epub 2019 Apr 5.

Department of Urology, Harbin Medical University Cancer Hospital, Harbin, China.

The present study reports a rare primitive neuroectodermal tumor (PNET) of prostate. A 27-year-old male was admitted to Harbin Medical University Cancer Hospital (Harbin, China) for dysuria and dyschezia. Magnetic resonance imaging (MRI) revealed a large mass that may involve the bladder and rectum next to the prostate. Read More

Case Rep Urol 2020 20;2020:8681429. Epub 2020 Mar 20.

Obstetrics and Gynecology Department, West Virginia University, Morgantown, West Virginia, USA.

True pelvic floor areas are uncommon conditions, but they can occur after extensive pelvic surgery including radical cystectomies or pelvic exenteration. We present the case of a patient with a persistent hernia that failed a native tissue repair and required a prosthetic mesh implant as definitive surgical treatment. Read More

Tech Coloproctol 2020 Jun 31;24(6):599-601. Epub 2020 Mar 31.

Department of Gastroenterological Surgery, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.

Background: Transanal minimally invasive surgery is a combination of single-port surgery and transanal surgery and was initially developed as a treatment for rectal tumors. Recently, this approach has also been used for more advanced or extended pelvic surgery.

Methods: We present a surgical video of combined laparoscopic and transperineal endoscopic total pelvic exenteration performed in a male patient with recurrent rectal cancer and discuss the pros and cons of this approach. Read More

Colorectal Dis 2020 Mar 16. Epub 2020 Mar 16.

Department of Colorectal Surgery, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.

Aim: Our aim was to identify whether personality traits and decision-making styles affect quality of life (QoL) outcomes and levels of psychological distress following pelvic exenteration (PE).

Method: Patients undergoing PE between 2008 and 2015 were identified from a prospectively maintained database at a single quaternary referral centre. Patients were invited to complete two validated questionnaires, with the Big Five inventory being used to assess personality traits and the Melbourne Decision Making Questionnaire to determine decision-making style. Read More

Taiwan J Obstet Gynecol 2020 Mar;59(2):314-317

Department SAIMLAL, Section of Anatomy, Laboratory of Electron Microscopy Pietro Motta, Sapienza University of Rome, Rome, Italy.

Objective: Primary vaginal leiomyosarcomas (LMS) are rare, easily recurrent tumours with an unknown etiology; the prognosis is poor and there is no consensus guideline on their management.

Case Report: A nodular, 25 × 23 x 28 mm-mass, infiltrating the urethra, was found in a 58-year-old woman. A biopsy showed a LMS of the vagina that was positive for vimentin, alpha-smooth muscle actin, caldesmon, desmin, p16 and p53. Read More

Eur J Surg Oncol 2020 Jun 20;46(6):1160-1166. Epub 2020 Feb 20.

Department of Surgery, Catharina Hospital Eindhoven, Eindhoven, the Netherlands.

Introduction: Surgery for locally advanced rectal cancer (LARC) or locally recurrent rectal cancer (LRRC) may require total pelvic exenteration with the need for urinary diversion. The aim of this study was to describe outcomes for ileal and colon conduits after surgery for LARC and LRRC.

Methods: All consecutive patients from two tertiary referral centers who underwent total pelvic exenteration for LARC or LRRC between 2000 and 2018 with cystectomy and urinary reconstruction using an ileal or colon conduit were retrospectively analyzed. Read More

Eur J Surg Oncol 2020 Jun 21;46(6):1138-1143. Epub 2020 Feb 21.

Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, Australia; Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, Australia; RPA Institute of Academic Surgery (IAS), Sydney, Australia; The University of Sydney, New South Wales, Australia.

Introduction: The purpose of this study was to review recommendations made from a specialist pelvic exenteration (PE) multidisciplinary team (MDT) and to provide insights as to the impact of the MDT on patient selection and clinical decision making.

Materials & Methods: A retrospective review was conducted at Royal Prince Alfred Hospital's PE MDT between June 2014 and December 2015. Data was collected from the recorded minutes of MDT meetings. Read More

Physiol Res 2019 12;68(Suppl 4):S509-S515

Department of Surgery, Second Faculty of Medicine, Charles University in Prague and Motol Faculty Hospital, Prague, Czech Republic.

Pelvic surgeries such as extirpation of the rectum or pelvic exenteration lead to a creation of a dead space, which can be cause of complication, such as bowel obstruction, perineal hernia, abscess or hematoma. A growing incidence of complication is expected in connection with the increasing use of laparoscopic and robotic approaches or ELAPE method. Since the bone structures do not allow compression, the only way to deal with the dead space is to fill it in. Read More

Rev Bras Ginecol Obstet 2020 Jan 27;42(1):35-42. Epub 2020 Feb 27.

Department of Gynecological Oncology, Istanbul University, Fatih, Istanbul, Turkey.

Objective:  To evaluate the outcomes of surgical treatment in patients with chemoradiotherapy (CRT)-resistant and locally advanced cervical cancer (LACC).

Methods:  Patients with LACC who underwent surgery due to resistance to CRT between 2005 and 2015 were reviewed retrospectively. Disease-free survival (DFS) and overall survival (OS) related factors were analyzed. Read More

Int J Gynecol Cancer 2020 Feb 19. Epub 2020 Feb 19.

Department of Gynaecologic Oncology, La Fe University and Polytechnic Hospital, Valencia, Spain.

Ann Surg 2020 Feb 14. Epub 2020 Feb 14.

Surgical Outcomes Research Center (SOuRCe), Sydney, Australia.

Objectives: To determine what constitutes a clear resection margin (R0) in patients with LRRC.

Summary Of Background Data: R0 is the most important predictor of survival in patients with LRRC. However, it is not clear what constitutes an R0. Read More

Prog Urol 2020 Feb 12;30(2):80-88. Epub 2020 Feb 12.

Department of urology, CHU Lille, university Lille, Claude Huriez hospital, 59000 Lille, France.

Purpose: To compare quality of life and functional outcomes associated with orthotopic neobladder (ONB) and ileal conduit (IC) after anterior pelvic exenteration for bladder cancer in women, through a multicentric cross-sectional study.

Methods: All women who have undergone an anterior pelvic exenteration associated with ONB or IC for a bladder cancer between January 2004 and December 2014 within the three participating university hospital centers and that were still alive in February 2016 were included. Three distinct auto-administered questionnaires were submitted to the patients: the EORTC QLQ-C30, the EORTC QLQ-BLmi30 and the SF-12. Read More

Colorectal Dis 2020 Feb 11. Epub 2020 Feb 11.

Aim: A total of 15-20% of patients with rectal cancer have liver metastases on presentation. The management of these patients is controversial. Heterogeneity in management strategies is considerable, with management often being dependent on local resources and available expertise. Read More

Ann Surg Oncol 2020 Jan 28. Epub 2020 Jan 28.

Surgery Oncology Unit, Peter MacCallum Cancer Centre, Melbourne, Australia.

Background: Pelvic exenteration has increasingly been shown to improve disease-free and overall survival for patients with locally advanced pelvic malignancies. Squamous cell carcinoma (SCC) is the second most common pelvic malignancy requiring exenteration.

Objective: The aim of this study was to report the clinical and oncological outcomes from patients treated with pelvic exenteration for anal and urogenital SCC from a single, high-volume unit. Read More

Gynecol Oncol 2020 Mar 23;156(3):749. Epub 2020 Jan 23.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Cir Esp 2020 Jan 21. Epub 2020 Jan 21.

Departamento de Cirugía Colorrectal y Hematológica, Servicio de Cirugía General y del Aparato Digestivo, Hospital de la Santa Creu i Sant Pau, Barcelona, España.

Introduction: Colovesical fistulae have significant morbidity. The aim of our study was to describe a case series of benign and malignant colovesical fistulae, focusing on the viability of the laparoscopic approach.

Methods: We reviewed the characteristics of 34 patients with diverticular and colon adenocarcinoma-related colovesical fistulae treated surgically from January 2001 to March 2018, 28 with elective surgery and 6 by urgent surgery. Read More

Colorectal Dis 2020 Jan 21. Epub 2020 Jan 21.

Colorectal Surgery Unit, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

Aim: Currently, there is no clear consensus on the role of extended pelvic resections for locally advanced or recurrent disease involving major vascular structures. The aims of this study were to report the outcomes of consecutive patients undergoing extended resections for pelvic malignancy involving the aortoiliac axis.

Methods: Prospective data were collected on patients having extended radical resections for locally advanced or recurrent pelvic malignancies, with aortoiliac axis involvement, requiring en bloc vascular resection and reconstruction, at a single institution between 2014 and 2018. Read More

Medicina (Kaunas) 2020 Jan 15;56(1). Epub 2020 Jan 15.

"Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

: Extended pelvic resection might be the option of choice in patients presenting locally advanced cervical cancer. However, the possibility of a co-existence of an ectopic, pelvic kidney that is invaded by such a tumor is extremely rare. : A 54-year-old female patient, diagnosed with locally advanced cervical cancer in the presence of a pelvic kidney, was submitted to surgery with curative intent. Read More

J Gastrointest Oncol 2019 Dec;10(6):1207-1214

Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, Australia.

There have been significant advances in the surgical management of locally advanced and recurrent rectal cancer in recent decades. Patient with advanced pelvic tumours involving adjacent organs and neurovascular structures, beyond the traditional mesorectal planes, who would have traditionally been considered irresectable at many centres, now undergo surgery routinely at specialised units. While high rates of morbidity and mortality were reported by the pioneers of pelvic exenteration (PE) in early literature, this is now considered historical data. Read More

Int J Gynecol Cancer 2020 Apr 6;30(4):558. Epub 2020 Jan 6.

Gynecologic Oncology and Minimally Invasive Gynecologic Surgery Unit (Department of Obstetrics and Gynecology), Hospital Universitario 12 de Octubre, Madrid, Comunidad de Madrid, Spain.

Colorectal Dis 2020 Jan 7. Epub 2020 Jan 7.

Surgical Outcomes Research Centre (SOuRCe), Sydney Local Health District and Sydney School of Public Health, University of Sydney, Sydney, New South Wales, Australia.

Aim: There is current debate about the optimal management of lateral pelvic lymph nodes (LPLNs) in rectal cancer between Western and Eastern centres. This paper aims to report the rate of histologically proven positive LPLNs in a group of patients undergoing the conventional Western approach to primary and recurrent rectal cancer.

Method: A retrospective cohort review of all patients who underwent LPLN dissection at Royal Prince Alfred Hospital in Sydney, Australia. Read More

Tech Coloproctol 2020 Feb 6;24(2):181-190. Epub 2020 Jan 6.

Colorectal Division of Cancer Surgery, Peter MacCallum Cancer Centre, 350 Grattan Street, Melbourne, VIC, 3000, Australia.

Background: Extensive multi-visceral resection, including components of the urinary tract, is often required to achieve clear resection margins, which is now well established as a key predictor of long-term survival for locally advanced pelvic tumours. The aims of this study were to analyse major morbidity and factors predicting complications and long-term outcomes following a urological procedure within extended radical resections.

Methods: Data were collected from prospective databases at two high-volume institutions specialising in extended radical resections for locally advanced and recurrent pelvic malignancies between 1990 and 2015. Read More

Ann Plast Surg 2020 02;84(2):196-200

From the Division of Plastic Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Background: Colorectal cancer is one of the most common and fatal malignancies in the United States. When localized to the distal gastrointestinal tract, surgical therapy includes abdominoperineal resection (APR) or pelvic exenteration (PEX). Subsequent ablative defects are considerable, impart concerning morbidity, and often necessitate autologous reconstruction. Read More

Int J Surg Case Rep 2020 9;66:187-191. Epub 2019 Dec 9.

Multidisciplinary Unit for Abdominal Pelvic Oncology Surgery (MUAPOS), University General Hospital of Castellon, Spain; Dept. of Medicine, University Jaume I (UJI), Castellon de la Plana, Spain.

Introduction: Radiation therapy and radical pelvic surgery, either radical cystectomy or pelvic exenteration, is the golden standard treatment for infiltrating bladder carcinoma, as well as advanced or recurrent cervical, vulvar, vaginal and endometrial cancer. However, due to the poor radiation sensitivity of the cervix and vagina, a high-radiation dose is required, leading to early and/or late onset urogenital complications in approximately 50% of the patients.

Case Presentation: The following case report describes a 64-year-old native Russian woman presenting a relapse of a vaginal cuff squamous cell carcinoma, who underwent a laterally extended endopelvic resection (LEER) followed by a neobladder reconstruction based on the Indiana pouch (IP) technique. Read More

Int Braz J Urol 2020 Jan-Feb;46(1):108-115

Department of Urology, Boston Medical Center/Boston University School of Medicine Boston.

Objective: Cystectomy with urinary diversion is the gold standard for muscle invasive bladder cancer. It also may be performed as part of pelvic exenteration for non-urologic malignancy, neurogenic bladder dysfunction, and chronic conditions that result in a non-functional bladder (e.g. Read More

Colorectal Dis 2020 May 5;22(5):521-528. Epub 2020 Jan 5.

Surgical Outcomes Research Centre (SOuRCe), Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Aim: The aim was to compare postoperative quality of life (QOL) between patients undergoing pelvic exenteration (PE) and pelvic exenteration with sacrectomy (PES), and to investigate the influence of high (L5-S2) vs low (≤ S3) sacrectomy on QOL and functional outcomes.

Method: Patients undergoing en bloc sacrectomy as part of a PE and PE alone from 2008 to 2015 were identified from a prospectively maintained database. QOL and functional outcomes were assessed using the 36-Item Short Form Survey, the European Organization for Research and Treatment of Cancer Colorectal Cancer questionnaire and Quality of Life questionnaire, the Revised Musculoskeletal Tumour Scale, the Lower Extremity Functional Scale, the Sexual Health Inventory for Men and the Female Sexual Function Index. Read More

Int J Gynecol Cancer 2020 02 2;30(2):233-240. Epub 2019 Dec 2.

Institut Claudius Regaud, Toulouse, Occitanie, France

Background: Pelvic exenteration and its reconstructive techniques have been associated with high postoperative morbidity and a negative impact on patient quality of life. The aim of our study was to compare postoperative complications and quality of life in patients undergoing continent compared with non-continent urinary diversion after pelvic exenteration for gynecologic malignancies.

Methods: We designed a multicenter study of patients from 10 centers who underwent an anterior or total pelvic exenteration with urinary reconstruction for histologically confirmed persistent or recurrent gynecologic malignancy after previous treatment with radiotherapy. Read More

J Laparoendosc Adv Surg Tech A 2020 May 27;30(5):558-563. Epub 2019 Nov 27.

Department of Colorectal Surgery and Tata Memorial Hospital, Parel, Mumbai, India.

Laparoscopic posterior exenteration (total and supralevator) is a complex and rarely done procedure. In this study we describe the surgical technique and short-term perioperative outcomes in 7 female patients of locally advanced carcinoma rectum operated with laparoscopic pelvic exenteration. We report 7 cases of carcinoma rectum involving either posterior wall of the uterus or vagina, which were operated with a laparoscopic procedure. Read More

J Surg Oncol 2020 Apr 27;121(5):718-729. Epub 2019 Nov 27.

Brazilian Society of Surgical Oncology, Rio de Janeiro, Brazil.

Background And Objectives: The primary treatment for locally advanced cases of cervical cancer is chemoradiation followed by high-dose brachytherapy. When this treatment fails, pelvic exenteration (PE) is an option in some cases. This study aimed to develop recommendations for the best management of patients with cervical cancer undergoing salvage PE. Read More

Tokai J Exp Clin Med 2019 Dec 20;44(4):68-72. Epub 2019 Dec 20.

Department of Obstetrics and Gynecology, Yokohama Municipal Citizen's Hospital, 56 Okazawa-cho, Hodogaya-ku, Yokohama 240-8555, Japan.

Adenoid cystic carcinoma (ACC) of the Bartholin's gland (BACC) is an extremely rare malignancy of the vulva. The characteristics of BACC include slow tumor growth and aggressive invasion, especially with perineural involvement. A 64-year-old Japanese woman complained of a mass and pain in the perineum. Read More

Int J Surg Case Rep 2019 5;65:279-283. Epub 2019 Nov 5.

Program in Peritoneal Surface Malignancies, MedStar Washington Hospital Center, 106 Irving St., NW, Suite 3900, Washington, DC, 20010, USA. Electronic address:

Background: Surgery which includes peritonectomy, visceral resections, and perioperative chemotherapy has been used extensively to treat peritoneal metastases from appendiceal mucinous adenocarcinoma. The results of treatment vary with the grade of the neoplasm, the extent of abdominal and pelvic disease and the completeness of tumor removal.

Methods: The clinical features, surgical procedures and outcome of two patients with mucinous appendiceal neoplasms were reviewed. Read More

J Surg Oncol 2019 Nov 19. Epub 2019 Nov 19.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, New York.

Background And Objectives: To examine the association between hospital surgical volume and perioperative mortality of pelvic exenteration performed for gynecologic malignancies.

Methods: A population-based retrospective study utilizing the Nationwide Inpatient Sample was conducted to examine pelvic exenteration for gynecologic malignancies from 2001 to 2011. Annualized hospital surgical volume was defined as the average number of procedures a hospital performed per year in which at least one case was performed, and this was correlated to perioperative mortality. Read More

In Vivo 2019 Nov-Dec;33(6):2299-2302

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

Background/aim: Clear cell vaginal adeno-carcinomas are rare tumors occurring in women which are usually treated by chemo radiotherapy with good outcomes. However, in certain cases, this treatment is not associated with complete response and a further surgery is needed.

Case Report: We present the case of a 38-year-old patient diagnosed with stage IVA clear cell vaginal cancer who had been previously submitted to radio chemotherapy and in whom the lesion persisted after the oncological treatment; therefore, the patient was proposed for surgery with curative intent. Read More