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Arch Gynecol Obstet 2019 Apr 22. Epub 2019 Apr 22.

Department of Obstetrics and Gynecology, University of Ulm, Prittwitzstr. 43, 89075, Ulm, Germany.

Background: Pelvic exenterations are a last resort procedure for advanced gynecologic malignancies with elevated risks in terms of patients' morbidity.

Methods: This single-center analysis reports surgical details, outcome and survival of all patients treated with exenteration for non-ovarian gynecologic malignancies at our university hospital during a 13-year time period. We collected data regarding patients and tumor characteristics, surgical procedures, peri- and postoperative management, transfusions, complications, and analyzed the impact on survival outcomes. Read More

Tech Coloproctol 2019 Apr 15. Epub 2019 Apr 15.

Department of Gastrointestinal Surgery, Faculty of Medicine, Kagawa University, Miki-cho, Kagawa, Japan.

Am J Surg 2019 Apr 4. Epub 2019 Apr 4.

Department of Gastrointestinal, Tumor and Endocrine Surgery, University of Colorado, Aurora, CO, USA.

Introduction: Optimization of preoperative nutritional status has been recommended and associated with improved outcomes for other oncologic procedures, but has not been studied in patients undergoing pelvic exenteration.

Methods: A retrospective chart review of 199 patients was conducted. Overall survival (OS) was calculated using the Kaplan-Meier method and multivariate analysis was performed with Cox proportional hazards. Read More

Chin Med J (Engl) 2019 Apr;132(8):976-979

Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400000, China.

Gynecol Oncol 2019 Apr 2. Epub 2019 Apr 2.

Department of Gynecologic Oncology Department, University Hospital La Fe, Valencia, Spain.

Objective: To determine pre-/intraoperative risk factors for anastomotic leak after modified posterior pelvic exenteration (MPE) or colorectal resection in ovarian cancer and to create a practical instrument for predicting anastomotic leak risk.

Background: In advanced ovarian cancer surgery, there is rather limited published evidence, drawn from a small sample, providing information about risk factors for anastomotic leak.

Methods: Eight hospitals participated in this retrospective study. Read More

Int J Gynecol Cancer 2019 Mar 28. Epub 2019 Mar 28.

Division of Gynecology Oncology, Department of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, Canada

Background: In patients with recurrent gynecologic malignancies isolated to the pelvis, pelvic exenteration is a potential option. 18F-Fluorodeoxyglucose (F-FDG) positron emission tomography/computed tomography (PET/CT), is often used to confirm no evidence of metastatic disease.

Objective: To assess the impact of PET/CT on clinical management of patients with recurrent gynecologic malignancies being considered for pelvic exenteration. Read More

Urology 2019 Mar 25. Epub 2019 Mar 25.

Department of Urology, Emory University School of Medicine, Atlanta, GA; Winship Cancer Institute, Emory Healthcare, Atlanta, GA.

Objective: To educate surgeons of distal colon urinary diversion as an alternative to ileal conduit. To assess peri-operative outcomes of distal colon conduit in pelvic exenteration including conduit-related, gastrointestinal, infectious, metabolic, and wound complications within 30 days, 31-89 days, and greater than 90 days from the time of surgery.

Materials & Methods: Forty-one patients who underwent distal colon urinary diversion for malignancy, fistula, or neurogenic bladder were identified in our IRB approved database from 1/2005 - 7/2017 RESULTS: Twenty-six (63. Read More

Gynecol Oncol 2019 Mar 21. Epub 2019 Mar 21.

Department of Radiation Oncology, Washington University School of Medicine, United States of America. Electronic address:

Purpose: To describe clinical outcomes in patients with isolated pelvic failures after definitive radiation treatment for cervical cancer.

Methods And Materials: Cervical cancer patients with isolated pelvic failure after definitive radiation with brachytherapy boost were identified in a tertiary academic center database from 1997 to 2016. All patients received an FDG-PET scan prior to their initial treatment and at the time of their first recurrence. Read More

Gynecol Oncol 2019 Mar 19. Epub 2019 Mar 19.

Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address:

Objective: To identify clinical and demographic characteristics associated with the absence of opioid usage on the day before discharge among patients undergoing open gynecologic surgery within an enhanced recovery after surgery (ERAS) program.

Methods: This was a single institution retrospective cohort study including all patients who underwent elective open gynecologic surgery as part of an ERAS program between November 1, 2014 and September 30, 2018 and who were discharged between post-operative day 2 and 7. Patients were excluded if they reported pre-existing chronic opioid use or underwent total pelvic exenteration. Read More

Indian J Surg Oncol 2019 Feb 23;10(Suppl 1):80-83. Epub 2019 Jan 23.

1Colorectal Services, Department of Surgical oncology, Tata Memorial Hospital, Ernest Borges Marg, Parel, Mumbai, 400 012 India.

Incidence of synchronous peritoneal metastases (PM) in colorectal cancer is approximately 5%, with another 5% of the patients develop metachronous PM. Colorectal PM has been hypothesized to be a loco-regional disease rather than a systemic spread, and cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) has been considered as a viable treatment option. Pelvic exenteration is an established treatment option for locally advanced rectal cancer, but it is associated with significant morbidity. Read More

Plast Reconstr Surg Glob Open 2019 Jan 15;7(1):e2015. Epub 2019 Jan 15.

Division of Plastic & Reconstructive Surgery, University of Wisconsin.

Background: Defects resulting from gynecologic oncology resections can range from small external defects to total exenterations, requiring complex pelvic reconstruction. We aim to investigate the patient and surgical factors that influence complication rates, reoperation rates, and length of stay. We hypothesize that this patient cohort will have high complication and reoperation rates that are likely most affected by their medical and extirpative surgery factors, with less direct impact from their reconstructive surgery procedures. Read More

Colorectal Dis 2019 Mar 11. Epub 2019 Mar 11.

Colorectal Division, GI services, Tata Memorial Center, Mumbai, India.

Surg Oncol 2019 Mar 26;28:109. Epub 2018 Nov 26.

Department of Digestive Oncological Surgery, West Oncologic Institut, Saint Herblain, France.

Ann Surg Oncol 2019 May 7;26(5):1569-1576. Epub 2019 Mar 7.

Department of Colorectal Surgery, National Cancer Center Hospital, Tokyo, Japan.

Background: Two procedures widely performed to treat locally advanced colorectal cancer adherent to the urinary bladder are total cystectomy (as part of pelvic exenteration) and partial cystectomy; however, little is known about outcomes following partial cystectomy.

Methods: A retrospective database of patients with colorectal cancer involving the urinary bladder who underwent R0 or R1 resection at our institution from 2001 to 2015 was constructed. The histological extent of bladder invasion and long-term outcomes were examined. Read More

Ann Surg Oncol 2019 May 6;26(5):1350. Epub 2019 Mar 6.

University of Heidelberg, Heidelberg, Germany.

Radiol Med 2019 Feb 26. Epub 2019 Feb 26.

Radiologia Diagnostica e Interventistica Generale, Area Diagnostica per Immagini, Dipartimento Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168, Rome, Italy.

The aim of this review is to illustrate normal computed tomography (CT) findings and the most common complications in patients who underwent pelvic exenteration (PE) for advanced, persistent or recurrent gynecological cancers. We review the various surgical techniques used in PE, discuss optimal CT protocols for postsurgical evaluation and describe cross-sectional imaging appearances of normal postoperative anatomic changes as well as early and late complications. The interpretation of abdominopelvic CT imaging after PE is very challenging due to remarkable modifications of normal anatomy. Read More

J Plast Reconstr Aesthet Surg 2019 Apr 9;72(4):565-571. Epub 2019 Jan 9.

Division of Plastic and Reconstructive Surgery, University of Ottawa, Ottawa, Ontario, Canada. Electronic address:

Purpose: Pelvic reconstruction following abdominoperineal resection or pelvic exenteration is associated with signification surgical site morbidity. Immediate pelvic reconstruction with a muscle flap is now the gold standard, associated with reduced perineal morbidity compared to primary closure alone. The purpose of the present study was to directly compare outcomes of VRAM and gracilis flap pelvic reconstruction following oncologic resection. Read More

Gynecol Oncol 2019 Feb 19. Epub 2019 Feb 19.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Objective: To examine changes in performance and outcomes of pelvic exenteration for gynecologic malignancies.

Methods: This is a population-based retrospective study examining the Nationwide Inpatient Sample between 2001 and 2015. Women with cervical, uterine, vaginal, and vulvar malignancies who underwent pelvic exenteration were examined. Read More

Br J Surg 2019 May 18;106(6):790-798. Epub 2019 Feb 18.

Department of Molecular Medicine and Surgery, Karolinska Institutet and Center of Digestive Diseases, Karolinska University Hospital, Stockholm, Sweden.

Background: Population-based studies of treatment of locally recurrent rectal cancer (LRRC) are lacking. The aim was to investigate the surgical treatment of patients with LRRC at a national population-based level.

Methods: All patients undergoing abdominal resection for primary rectal cancer between 1995 and 2002 in Sweden with LRRC as a first event were included. Read More

J Investig Med High Impact Case Rep 2019 Jan-Dec;7:2324709619828408

1 Brookdale University Hospitals and Medical Center, New York, NY, USA.

Female urethral diverticular cancer is a very rare entity with only around 100 cases reported so far in literature and accounts for <1% of all malignancies. In this article, we present a 47-year-old African American female with repeated hospital visits for urinary retention, hematuria, and urinary tract infections. Initial computed tomography imaging and cystoscopy was unremarkable except for a distended urinary bladder. Read More

Colorectal Dis 2019 Apr 26;21(4):490. Epub 2019 Feb 26.

Department of Digestive Surgery, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

Zhonghua Wei Chang Wai Ke Za Zhi 2019 Jan;22(1):59-65

Department of General Surgery, Peking University First Hosiptal, Beijing 100034,China.

Objective: To investigate the value of neoadjuvant chemoradiotherapy (nCRT) combined with total pelvic exenteration (TPE) in the treatment of primary T4b rectal cancer.

Methods: A retrospective cohort study was conducted to analyze the clinicopathological data of 31 patients with primary T4b rectal cancer who underwent TPE from January 2008 to December 2015 at Peking University First Hospital.

Inclusion Criteria: preoperative clinical stage (cTNM) was defined as cT4b primary rectal cancer with only front wall Invasion; the lower edge of tumor was within 10 cm from the anal margin; TPE was performed; R0 resection was confirmed by pathology. Read More

Gan To Kagaku Ryoho 2018 Dec;45(13):2027-2029

Dept. of Surgery, NTT West Osaka Hospital.

We report a case of advanced sigmoid colon cancer that was resected after chemoradiation therapy(CRT)following ineffective chemotherapy. A 59-year-old woman harbored a lower abdominal tumor the size of an infant's head and was diagnosed with a huge sigmoid colon cancer with invasion to the urinary bladder and metastases to the para-aortic lymph nodes. The patient received 2 courses of modified FOLFOX6(mFOLFOX6)plus cetuximab therapy, which was assessed as ineffective; She then received CRTwith 50. Read More

Gan To Kagaku Ryoho 2018 Dec;45(13):2048-2050

Dept. of Surgery, Amagasaki Chuo Hospital.

We report a case of locally advanced colon cancer that directly invaded the rectum wall and uterus resulting in huge mass in the whole pelvis that we could successfully made complete radical resection of the whole tumor without exposing the tumor to the surgical margin after the triplet chemotherapy. The patient was a 57-year-old woman complaining of anus pain, melena, fever, and weight loss. Although swelling of the regional lymph node was observed, no distant metastasis was found resulting in clinical diagnosis of Stage Ⅲb. Read More

Mol Clin Oncol 2019 Jan 26;10(1):92-96. Epub 2018 Oct 26.

Department of Obstetrics and Gynecology, Hakodate Central General Hospital, Hakodate, Hokkaido 040-8585, Japan.

The present report describes a case of laparoscopic posterior pelvic exenteration of a primary adenocarcinoma of the rectovaginal septum (PARS) without associated endometriosis. A 49-year-old woman was admitted to hospital for rectal bleeding. Imaging studies showed a 7-cm solid tumor located in the rectovaginal septum, presenting with invasion to the posterior aspect of the uterine cervix and the anterior rectal wall. Read More

Gynecol Oncol Rep 2019 Feb 21;27:46-49. Epub 2018 Dec 21.

University of Arizona, Tucson, AZ, USA.

Mucinous adenocarcinoma of the endometrium (MACE) is a rare subtype of endometrial adenocarcinoma that often presents a significant diagnostic challenge due to its variation from the conventional morphologic appearance of endometrioid epithelium. This case report is of a woman who has survived 4 years after pelvic exenteration and subsequent vulvectomy for recurrent MACE. Read More

J Minim Invasive Gynecol 2019 Jan 4. Epub 2019 Jan 4.

Department of Woman s and Child Health, Fondazione Policlinico Universitario "Agostino Gemelli", IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy (Drs. Bizzarri, Fagotti, Cappuccio, Gallotta, Scambia, and Vizzielli). Electronic address:

Study Objective: To assess the feasibility and efficacy of minimally invasive pelvic exenteration (MIPE) in a multi-institutional Italian case series of women with gynecologic cancer and a review of the literature.

Design: Retrospective cohort study (Canadian Task Force classification II-2).

Setting: Three Italian university/teaching hospitals: "Agostino Gemelli" Foundation University Hospital in Rome, "ARNAS Civico Di Cristina Benfratelli" Hospital in Palermo, and "Maggiore della Carità" Hospital in Novara. Read More

Ann Ital Chir 2018 ;89:229-236

Introduction: Although multi-organ resections (MOR) are recommended by international guidelines for advanced colorectal cancer, the literature shows that the morbidity and mortality that accompanies these complex interventions limits the number of patients receiving this treatment. The purpose of our study was to analyse the immediate and remote results obtained after MOR and to identify potential factors that might influence the outcome.

Material And Method: Our study is a retrospective cohort which included patients surgically treated in our service for locally advanced colorectal cancer. Read More

World J Gastroenterol 2018 Dec;24(45):5144-5153

Colorectal Unit, Hospital Universitario y Politecnico La Fe, University of Valencia, Valencia 46026, Spain.

Aim: To identify short-term and oncologic outcomes of pelvic exenterations (PE) for locally advanced primary rectal cancer (LAPRC) in patients included in a national prospective database.

Methods: Few studies report on PE in patients with LAPRC. For this study, we included PE for LAPRC performed between 2006 and 2017, as available, from the Rectal Cancer Registry of the Spanish Association of Surgeons [Asociación Española de Cirujanos (AEC)]. Read More

Colorectal Dis 2019 Mar 16;21(3):365-369. Epub 2019 Jan 16.

Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, Australia.

Aim: Perineal wound complications and pelvic abscesses remain a major source of morbidity after total pelvic exenteration. The void created in the pelvis after these multi-visceral resections leads to fluid accumulation and translocation of bowel within the pelvic cavity, which may increase the risk of pelvic abscess, perineal fluid discharge with perineal wound dehiscence and prolonged ileus. This study describes a novel technique using degradable synthetic mesh with overlying omentum to preclude small bowel and fill the empty space after total pelvic exenteration, and aimed to investigate the rate of pelvic abscess and perineal wound-related complications in this group. Read More

Indian J Surg Oncol 2018 Dec 20;9(4):552-557. Epub 2018 Jul 20.

22nd Department of Surgery, Attikon Hospital, University of Athens Medical School, 1 Rimini Str, 124 10 Chaidari, Greece.

Pelvic exenteration (PE) is one of the most drastic operations in surgical oncology, associated with severe morbidity and mortality. The objective of our study was to review our experience of PE in terms of surgical characteristics, complications, and overall survival. All patients who had PE surgery between January 1999 and December 2015 were identified. Read More

Indian J Surg Oncol 2018 Dec 23;9(4):547-551. Epub 2018 Jul 23.

5Department of Biotechnology and Microbiology, Karnatak University, Dharwad, 580003 Karnataka India.

Involvement of the bladder by colorectal cancer is sufficiently rare to be encountered by an individual surgeon on an infrequent basis. Extirpative procedures for advanced colorectal cancers can involve partial/total bladder resections. In patients without evidence of distant metastatic disease, a reasonable therapeutic effect can be expected when negative surgical margins are obtained. Read More

Ann Surg Oncol 2019 May 5;26(5):1340-1349. Epub 2018 Dec 5.

Chirurgische Klinik I, Lukaskrankenhaus Neuss, Neuss, Germany.

Background: Pelvic exenteration (PE) is a complex and challenging surgical procedure. The reported results of this procedure for primary and recurrent disease are limited and conflicting.

Methods: This study analyzed patient outcomes after all PEs performed in the authors' department between October 2001 and December 2016. Read More

Ginekol Pol 2018;89(11):618-626

Clinical Department of Gynecological Oncology, Professor Franciszek Lukaszczyk Oncology Center, Bydgoszcz, Poland; Department of Oncology, Radiotherapy and Oncological Gynecology, Ludwik Rydygier Collegium Medicum, Nicolaus Copernicus University, Bydgoszcz, Poland.

Objectives The aim of our study has been to determine the association between the appearance of infection after modified posterior pelvic exenteration (MPE) and TTC (time to adjuvant chemotherapy) and to examine whether the infection impacts clinical results by delaying the start of chemotherapy. Material and methods The present, retrospective study analyzed 77 patients who had undergone MPE followed by adjuvant chemotherapy. Either no residual tumor or tumor less than 2. Read More

Tech Coloproctol 2018 11 1;22(11):835-845. Epub 2018 Dec 1.

Colorectal Unit, Derriford Hospital, Plymouth Hospital NHS Trust, Plymouth, UK.

Background: Pelvic exenteration represents the best treatment option for cure of locally advanced or recurrent rectal cancer. This systematic review sought to evaluate current literature regarding short and long term treatment outcomes and long term survival following pelvic exenteration.

Methods: A systematic search of the MEDLINE, PubMed and Ovid databases was conducted to identify suitable articles published between 2001 and 2016. Read More

Gynecol Oncol 2019 01 16;152(1):218-219. Epub 2018 Nov 16.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea. Electronic address:

Gynecol Oncol 2019 01 8;152(1):151-156. Epub 2018 Nov 8.

Division of Gynecologic Surgery, Mayo Clinic, Rochester, MN, USA. Electronic address:

Objective: Pelvic exenteration (PE) is an extensive surgery associated with high rates of postoperative morbidity and mortality. The absence of well-defined preoperative selection criteria to identify patients eligible for PE prompted the assessment of pre-operative predictors of 30-day major surgical complications.

Methods: Demographics and surgical characteristics of patients undergoing PE for gynecologic cancer in a single institution between 01/2004-12/2016 were reviewed. Read More

Int J Gynecol Cancer 2018 11;28(9):1796-1804

Lifespan Cancer Institute, Warren Alpert Medical School of Brown University, Providence, RI.

Objective: The aim of this study was to evaluate contemporary practices and opinions among gynecologic oncologists regarding the use of total pelvic exenteration (TPE) for palliative intent.

Methods: This cross-sectional study of the membership of the Society of Gynecologic Oncology utilized an electronic survey to assess the opinions and practice patterns of gynecologic oncologists regarding TPEs. The primary outcome was willingness to consider a TPE for palliative intent, and demographic and practice characteristics were collected for correlation. Read More

Int J Gynecol Cancer 2018 11;28(9):1805-1806

Department of Obstetrics and Gynecology, Ospedale Maggiore della Carità Università degli Studi del Piemonte Orientale, Novara, Italy.

Study Objective: The video article describes a laparoscopic anterior pelvic exenteration with radical vaginectomy using the 3-dimensional (3D) vision and multifunction instruments.

Methods: This is a step-by-step video presentation of the laparoscopic anterior pelvic exenteration (Canadian Task Force classification III). Although the therapeutic benefit of the PE remains controversial, it is often performed in women with centrally recurrent pelvic tumors that previously received radiation therapy or in the locally advanced cases (ie, stage IIb-IVa) resistant to radiochemotherapy. Read More

Tech Coloproctol 2018 09 10;22(9):663-671. Epub 2018 Oct 10.

Department of Surgery, Complex Cancer Clinic, St. Mark's Hospital, London, UK.

Background: Complete pathological resection of locally advanced and recurrent anorectal cancer is considered the most important determinant of survival outcome. Involvement of the retropubic space with cancer threatening or involving the penile base poses specific challenges due to the potential for margin involvement and blood loss from the dorsal venous plexus. In the present study we evaluate a new transperineal surgical approach to excision of anterior compartment organs involved or threatened by cancer which facilitates exposure and visualisation of the bulbar urethra and the deep vein of the penis caudal to the retropubic space and penile base. Read More

BJS Open 2018 Sep 22;2(5):328-335. Epub 2018 May 22.

Surgical Outcomes Research Centre Royal Prince Alfred Hospital Sydney New South Wales Australia.

Background: Pelvic exenteration (PE) is the preferred treatment available for selected patients diagnosed with locally advanced or recurrent cancer confined to the pelvis. Currently, the majority of the literature reports only on short-term survival and quality-of-life (QoL) outcomes. The aim of this prospective cohort study was to describe long-term survival and QoL outcomes following PE. Read More

Eur J Surg Oncol 2018 12 3;44(12):1929-1934. Epub 2018 Sep 3.

Introduction: The objective of this study was to report a 30-year experience of PE for gynecologic malignancies in a cancer center.

Materials And Methods: A retrospective study was conducted at Institut Paoli-Calmette including patients who underwent PE for gynecologic malignancies. Four periods were evaluated: P1 before 1992, P2 between 1993 and 1999, P3 between 2000 and 2006 and P4 after 2006. Read More

Am J Obstet Gynecol 2018 Dec 18;219(6):598.e1-598.e10. Epub 2018 Sep 18.

Department of Obstetrics, Gynecology, and Reproductive Sciences, Temple University Hospital, Philadelphia, PA; Division of Gynecologic Oncology, Fox Chase Cancer Center, Philadelphia, PA.

Background: Patients with ovarian cancer experience a high rate of anemia throughout their treatment course, with rates that range from 19-95%. Blood transfusions offer symptom relief but may be costly, are limited in supply, and have been associated with worse 30-day surgical morbidity and mortality rates.

Objective: The purpose of this study was to identify risk factors for blood transfusion with packed red blood cell and to develop a transfusion risk score to identify patients who undergo surgery for ovarian cancer and who are at lowest risk for a blood transfusion. Read More

Urol J 2018 Sep 11. Epub 2018 Sep 11.

Department of Surgery, Matsuyama Shimin Hospital, Ehime, Japan.

A 72-year-old Japanese man presented to the hospital with complaints of gross hematuria. Contrast enhanced computed tomography revealed a broad-based, approximately 3-cm bladder tumor near the right ureteral orifice and a 5-cm mass located between the prostate and rectum. The patient underwent transurethral resection of the bladder tumor and a transrectal biopsy of the lesion. Read More

Support Care Cancer 2019 May 5;27(5):1853-1860. Epub 2018 Sep 5.

Royal Prince Alfred Hospital, Sydney, NSW, Australia.

Purpose: Compliance with oral nutrition support (ONS) is poorly reported in the literature. Many factors influence compliance, which could mask the true benefits of preoperative ONS. Surgical oncology patients, including pelvic exenteration patients, are often requested by healthcare workers to consume nutrition supplements before surgery. Read More

Aktuelle Urol 2018 Sep 5;49(5):405-411. Epub 2018 Sep 5.

Klinik für Urologie, Uro-Onkologie, spezielle urologische und roboter-assistierte Chirurgie, Universitätsklinikum Köln, Köln.

If prostate cancer recurs after primary treatment, deprivation therapy with LHRH analogues or antagonists is the treatment of choice in men with metastatic prostate cancer. However, this treatment only achieves palliative results. Median time to progression ranges between 11 and 78 months. Read More

Gynecol Oncol 2018 10 1;151(1):178-179. Epub 2018 Sep 1.

Department of Surgical Oncology, Institut Claudius Regaud, Institut Universitaire du Cancer de Toulouse - Oncopole, Toulouse, France; INSERM, CRCT Team 19, ONCOSARC - Oncogenesis of sarcomas, Toulouse, France. Electronic address:

Urology 2018 Nov 29;121:203.e1-203.e5. Epub 2018 Aug 29.

Department of Pathology, Johns Hopkins Medical Institute, Baltimore, MD; Department of Urology, Johns Hopkins Medical Institute, Baltimore, MD; Department of Oncology, Johns Hopkins Medical Institute, Baltimore, MD. Electronic address:

Objective: To better characterize granular cell tumor of the bladder, with only 20 cases reported to date and unclear management guidelines.

Methods: We report five benign and one malignant granular cell tumor of the bladder.

Results: Patients were in the age range of 33 to 73 years. Read More

Int J Gynecol Cancer 2018 10;28(8):1569-1575

Gynecologic Oncology, Fondazione Policlinico A. Gemelli, IRCCS.

Background: Platinum-based chemotherapy plus bevacizumab is the new standard of care in stage IVB cervical cancer (CC) patients. In this new scenario, radical surgery could be offered in selected cases with an optimal clinical response. Potential surgical complications related to previous bevacizumab treatment have never been described before in this type of setting. Read More

J Obstet Gynaecol Res 2018 Dec 21;44(12):2186-2189. Epub 2018 Aug 21.

Department of Obstetrics and Gynecology, Mie University School of Medicine, Tsu, Japan.

A 52-year-old woman presented to our hospital complaining of genital bleeding and was found to have a 50-mm vaginal tumor that involved the bladder, rectum, and small bowel and extended to the left pelvic side wall. Her history included a bilateral salpingo-oophorectomy and a total abdominal hysterectomy for fibroids and endometriosis. She had been prescribed estrogen replacement therapy (1. Read More