Antioxidants (Basel) 2021 Aug 21;10(8). Epub 2021 Aug 21.
Department of Molecular Medicine, School of Medicine, BK21 Plus KNU Biomedical Convergence Program, Cell and Matrix Research Institute, Kyungpook National University, Daegu 41944, Korea.
Vitamin B3 (nicotinic acid, niacin) deficiency causes the systemic disease pellagra, which leads to dermatitis, diarrhea, dementia, and possibly death depending on its severity and duration. Vitamin B3 is used in the synthesis of the NAD family of coenzymes, contributing to cellular energy metabolism and defense systems. Although nicotinamide (niacinamide) is primarily used as a nutritional supplement for vitamin B3, its pharmaceutical and cosmeceutical uses have been extensively explored. Read More