2,149 results match your criteria Pediatrics Tachycardia


Pediatric Pulseless Ventricular Tachycardia: A Simulation Scenario for Fellows, Residents, Medical Students, and Advanced Practitioners.

MedEdPORTAL 2016 Jun 3;12:10407. Epub 2016 Jun 3.

Assistant Professor of Pediatric Critical Care Medicine, Medical College of Wisconsin.

Introduction: Pulseless ventricular tachycardia is an uncommon presentation to the pediatric emergency department (ED) or the pediatric ICU (PICU); however, if unrecognized or inappropriately treated, it can lead to significant morbidity and mortality. This resource was created to simulate a high-acuity and low-frequency event targeting PICU fellows, pediatric emergency medicine fellows, pediatric residents, ED residents, medical students, and advanced nursing providers.

Methods: This scenario details the case of a 12-year-old boy with a history of heart transplant who presents with the chief complaint of dizziness. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15766/mep_2374-8265.10407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6464469PMC

Maternal heart rate patterns under resting conditions in late pregnancy.

Trends Res 2018 Sep 12;1(3). Epub 2018 Sep 12.

Department of Psychiatry, Columbia University Medical Center, New York, NY, USA.

Objectives: To describe maternal heart rate patterns observed during antenatal monitoring under resting conditions between the gestational ages of 34 to 38 weeks and to demonstrate its associations with uterine activity.

Methods: Each participant had five high quality ECG electrodes attached to her anterior abdominal wall which were connected to the Monica AN24 device to collect raw electrical signals from the maternal and fetal ECG and signals of uterine activity. Proprietary software was then used to download the raw data and extract the maternal and fetal heart rate patterns and uterine activity. Read More

View Article

Download full-text PDF

Source
https://www.oatext.com/maternal-heart-rate-patterns-under-re
Publisher Site
http://dx.doi.org/10.15761/TR.1000116DOI Listing
September 2018
1 Read

Is prone sleeping dangerous for neonates? Polysomnographic characteristics and NDN gene analysis.

Ci Ji Yi Xue Za Zhi 2019 Apr-Jun;31(2):113-117

Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.

Objective: Prone sleep is an identified risk factor for sudden infant death syndrome, possibly due to reduced blood pressure, cerebral oxygenation, and impaired cerebral vascular control. Cardiac and respiratory responses in neonates during supine and prone sleep have not been reported.

Materials And Methods: In this study, daytime polysomnography (PSG) data from 17 neonates aged 2-3 days during supine and prone sleep were reported and the NDN gene, an important gene for neonatal respiratory control, was sequenced for correlation with neonatal respiratory parameters. Read More

View Article

Download full-text PDF

Source
http://www.tcmjmed.com/text.asp?2019/31/2/113/236553
Publisher Site
http://dx.doi.org/10.4103/tcmj.tcmj_29_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450148PMC
April 2019
1 Read

Fascicular tachycardia in infancy and the use of verapamil: a case series and literature review.

Arch Dis Child 2019 Apr 20. Epub 2019 Apr 20.

Green Lane Paediatric and Congenital Cardiac Services, Starship Children's Hospital, Auckland, New Zealand.

Objective: Guidelines state that verapamil is contraindicated in infants. This is based on reports of cardiovascular collapse and even death after rapid intravenous administration of verapamil in infants with supraventricular tachycardia (SVT). We wish to challenge this contraindication for the specific indication of verapamil sensitive ventricular tachycardia (VSVT) in infants. Read More

View Article

Download full-text PDF

Source
http://adc.bmj.com/lookup/doi/10.1136/archdischild-2018-3156
Publisher Site
http://dx.doi.org/10.1136/archdischild-2018-315617DOI Listing
April 2019
1 Read

Use of mean platelet volume in the assessment of intrauterine infection in newborns with combined thrombocytopenia and leukopenia at birth.

J Matern Fetal Neonatal Med 2019 Apr 14:1-161. Epub 2019 Apr 14.

a Department of Pediatrics , University of Kansas Medical Center , Kansas City , Kansas , USA.

Objective: Intrauterine stress can be reflected on hematological disturbance at birth. Thrombocytopenia and leukopenia may be a result of exposure to maternal hypertensive disorders but may also indicate fetal inflammatory response to intrauterine infection, prompting empiric antibiotics use during the initial assessment after birth. Emerging data suggest long-term adverse health outcomes associated with antibiotics exposure early in life. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14767058.2019.1608174DOI Listing
April 2019
1 Read

Association between hypotension and serious illness in the emergency department: an observational study.

Arch Dis Child 2019 Apr 4. Epub 2019 Apr 4.

Department of Pediatrics, Erasmus MC-Sophia, Rotterdam, The Netherlands.

Background: The value of routine blood pressure measurement in the emergency department (ED) is unclear.

Objective: To determine the association between hypotension in addition to tachycardia and the Shock Index for serious illness.

Design: Observational study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/archdischild-2018-316231DOI Listing
April 2019
3 Reads

Heterogeneity in the Definition and Clinical Characteristics of Dumping Syndrome: a Review of the Literature.

Obes Surg 2019 Apr 2. Epub 2019 Apr 2.

Department of Abdominal Surgery, University Hospital Antwerp, Edegem, Belgium.

Background: No real consensus regarding the definition of dumping syndrome (DS) seems to exist and few subtyping is used in clinical practice. Knowledge is needed for correct design of trials and establishment of uniform treatment strategies. The aim of this study is to explore the distribution of clinical characteristics related to the subtypes of DS. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11695-019-03818-3
Publisher Site
http://dx.doi.org/10.1007/s11695-019-03818-3DOI Listing
April 2019
4 Reads

Acute Outcomes for Cryoablation in Pediatric Patients with Perinodal Tachyarrhythmia: Single Center Report.

Acta Cardiol Sin 2019 Mar;35(2):134-143

Department of Pediatrics, National Taiwan University Hospital, Taipei.

Background: Cryoablation is an alternative treatment for atrioventricular nodal reentrant tachycardia (AVNRT) and right anteroseptal and midseptal accessory pathways (APs) with a low complication rate. A high recurrence rate is still a concern in pediatric patients.

Methods: From February 2015 to March 2017, all consecutive patients who underwent cryoablation for supraventricular tachycardia were included in this study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.6515/ACS.201903_35(2).20180903ADOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434415PMC
March 2019
1 Read

Cardiovascular Collapse with Intravenous Amiodarone in Children: A Multi-Center Retrospective Cohort Study.

Pediatr Cardiol 2019 Mar 30. Epub 2019 Mar 30.

Children's Heart Centre, University of British Columbia, Vancouver, BC, Canada.

Objective: To determine the incidence of cardiovascular collapse in children receiving intravenous (IV) amiodarone and to identify the population at risk.

Design: A multicenter study of patients ≤ 18 years of age who received intravenous amiodarone between January 2005 and December 2015. A retrospective analysis was performed to identify patients who developed cardiovascular collapse (bradycardia and/or hypotension). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00246-019-02090-7DOI Listing
March 2019
1 Read

A large deletion in RYR2 exon 3 is associated with nadolol and flecainide refractory catecholaminergic polymorphic ventricular tachycardia.

Pacing Clin Electrophysiol 2019 Mar 25. Epub 2019 Mar 25.

Center for Arrhythmia Care, Heart & Vascular Center, Pritzker School of Medicine of the University of Chicago, Chicago, Illinois.

We report a 17-year-old boy with a large RYR2 exon 3 deletion who has a severe catecholaminergic polymorphic ventricular tachycardia (CPVT) phenotype characterized by refractoriness to both nadolol and flecainide which has previously not been reported in this subgroup of CPVT patients. Treatment options in a patient like ours are therefore limited and sympathectomy and implantable cardioverter-defibrillator implantation should be considered early in the treatment course as was done in this patient. In contrast to other CPVT patients who do not usually have structural cardiac abnormalities, these patients are at a high risk of developing left ventricular noncompaction or dilated cardiomyopathy and therefore might benefit from cardiac imaging at regular intervals. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pace.13668DOI Listing
March 2019
1 Read

Pregnancy in Catecholaminergic Polymorphic Ventricular Tachycardia.

JACC Clin Electrophysiol 2019 Mar 26;5(3):387-394. Epub 2018 Dec 26.

Heart Rhythm Services, Division of Cardiology, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

Objectives: This investigation was a retrospective study of catecholaminergic polymorphic ventricular tachycardia (CPVT) patients in Canada and the Netherlands to compare pregnancy, postpartum, and nonpregnant event rates.

Background: CPVT is characterized by life-threatening arrhythmias during exertion or emotional stress. The arrhythmic risk in CPVT patients during pregnancy is unknown. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacep.2018.10.019DOI Listing
March 2019
2 Reads

Use of whole exome sequencing in the NICU: Case of an extremely low birth weight infant with syndromic features.

Mol Cell Probes 2019 Mar 15. Epub 2019 Mar 15.

University of Cologne, Medical Faculty and University Hospital, Department of Pediatrics, Division of Pediatric Neurology, Germany; University of Cologne, Medical Faculty, Center for Molecular Medicine Cologne (CMMC), Germany. Electronic address:

Single gene (Mendelian) disorders are one of the leading causes of neonatal morbidity and mortality. However, in the setting of preterm birth phenotypic features of genetic diseases are often undifferentiated and are clinically very difficult to interpret based on the wide range of differential diagnoses. We report an extremely low birth weight infant (ELBW) born prematurely at 23 + 0 gestational weeks after twin pregnancy with a novel clinical manifestation with persistent hyperglycaemia as well as the known manifestations of disease-associated hypokinesia, renal salt wasting, and multifocal atrial tachycardia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mcp.2019.03.002DOI Listing
March 2019
2 Reads

Methamphetamine-Induced Tachydysrhythmia in an Adolescent in Diabetic Ketoacidosis.

J Emerg Med 2019 Mar 14. Epub 2019 Mar 14.

Division of Emergency and Transport Medicine, Department of Pediatrics, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California.

Background: Diabetic ketoacidosis (DKA) is a common complication affecting patients with type 1 diabetes, and DKA is associated with dehydration and electrolyte abnormalities. Supraventricular tachycardia (SVT), although a common tachydysrhythmia in the pediatric population, remains a rare entity in patients presenting with DKA.

Case Report: We describe a case of first-time SVT in an adolescent patient with DKA and recent methamphetamine abuse, with both factors likely predisposing him to develop a tachydysrhythmia. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S07364679193003
Publisher Site
http://dx.doi.org/10.1016/j.jemermed.2019.01.031DOI Listing
March 2019
6 Reads

Cardiac Rhythm Disturbances in Heterotaxy Syndrome.

Pediatr Cardiol 2019 Mar 14. Epub 2019 Mar 14.

Department of Pediatrics, University of Tokyo Hospital, Tokyo, Japan.

Objective: Heterotaxy syndrome is associated with complex cardiac malformations and cardiac conduction system abnormalities. Those with right atrial isomerism (RAI) have dual sinus nodes and dual atrioventricular nodes predisposing them to supraventricular tachycardia (SVT). Those with left atrial isomerism (LAI) lack a normal sinus node and are at risk of sinus node dysfunction (SND) and atrioventricular block (AV block). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00246-019-02087-2DOI Listing
March 2019
2 Reads

A comparison of oral flecainide and amiodarone for the treatment of recurrent supraventricular tachycardia in children.

Pacing Clin Electrophysiol 2019 Mar 15. Epub 2019 Mar 15.

Division of Cardiology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California.

Background: Supraventricular tachycardia (SVT) in children can be difficult to treat when first-line therapies (beta-blockade or digoxin) are not effective. Both flecainide and amiodarone are used as second-line therapies. We sought to compare the efficacy and safety of flecainide and amiodarone in pediatric patients with recurrent SVT. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pace.13662DOI Listing
March 2019
2 Reads

Clinical presentation and early predictors for poor outcomes in pediatric myocarditis: A retrospective study.

World J Clin Cases 2019 Mar;7(5):548-561

Department of Pediatric Nephrology, Puerta del Mar University Hospital, Cadiz 11009, Spain.

Background: Myocarditis is an important cause of morbidity and mortality in children, leading to long-term sequelae including chronic congestive heart failure, dilated cardiomyopathy, heart transplantation, and death. The initial diagnosis of myocarditis is usually based on clinical presentation, but this widely ranges from the severe sudden onset of a cardiogenic shock to asymptomatic patients. Early recognition is essential in order to monitor and start supportive treatment prior to the development of severe adverse events. Read More

View Article

Download full-text PDF

Source
https://www.wjgnet.com/2307-8960/full/v7/i5/548.htm
Publisher Site
http://dx.doi.org/10.12998/wjcc.v7.i5.548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406197PMC
March 2019
4 Reads

Tuberous sclerosis presenting with tachycardia as an autonomic phenomenon of epilepsy.

Pediatr Int 2019 Mar 10;61(3):307-309. Epub 2019 Mar 10.

Department of Pediatrics, Kakogawa Central City Hospital, Kakogawa, Hyogo, Japan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ped.13782
Publisher Site
http://dx.doi.org/10.1111/ped.13782DOI Listing
March 2019
4 Reads

Low-dose l-isoproterenol versus salbutamol in hospitalized pediatric patients with severe acute exacerbation of asthma: A double-blind, randomized controlled trial.

Allergol Int 2019 Mar 5. Epub 2019 Mar 5.

Department of Development Strategy, Center for Clinical Research and Development, National Center for Child Health and Development, Tokyo, Japan.

Background: Although the guidelines in most countries do not recommend continuous inhalation of l-isoproterenol to treat pediatric patients with acute severe exacerbation of asthma, lower dose of l-isoproterenol has been widely used in Japan. To determine whether the efficacy of low-dose l-isoproterenol was superior to that of salbutamol, we conducted a double-blind, randomized controlled trial.

Methods: Hospitalized patients aged 1-17 years were eligible if they had severe asthma exacerbation defined by the modified pulmonary index score (MPIS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.alit.2019.02.001DOI Listing
March 2019
1 Read

Computational Identification of Ventricular Arrhythmia Risk in Pediatric Myocarditis.

Pediatr Cardiol 2019 Apr 6;40(4):857-864. Epub 2019 Mar 6.

Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.

Children with myocarditis have increased risk of ventricular tachycardia (VT) due to myocardial inflammation and remodeling. There is currently no accepted method for VT risk stratification in this population. We hypothesized that personalized models developed from cardiac late gadolinium enhancement magnetic resonance imaging (LGE-MRI) could determine VT risk in patients with myocarditis using a previously-validated protocol. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00246-019-02082-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451890PMC
April 2019
2 Reads

Evolution of post-pulmonary vein isolation atrial fibrillation inducibility at redo ablation: Electrophysiological evidence of extra-pulmonary vein substrate progression.

Heart Rhythm 2019 Feb 25. Epub 2019 Feb 25.

Cardiology Division, Geneva University Hospitals, Geneva, Switzerland.

Background: The electrophysiological substrate underlying atrial fibrillation (AF) progression remains difficult to identify.

Objective: The goals of this study were to study the evolution of post-pulmonary vein isolation (PVI) AF inducibility (AFI) after AF ablation and to compare patients with organized atrial tachycardia recurrence (OATr) and those with paroxysmal and persistent AF recurrence.

Methods: We studied 99 patients who underwent de novo AF ablation (p1) and redo ablation (p2) for AF recurrence (AFr) or OATr. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2019.02.026DOI Listing
February 2019
1 Read

Fetal arrhythmias: Diagnosis and management.

Indian Pacing Electrophysiol J 2019 Feb 25. Epub 2019 Feb 25.

Department of Pediatrics, Oregon Health & Science University, Portland, OR, USA.

This article reviews important features for improving the diagnosis and management of fetal arrhythmias. The normal fetal heart rate ranges between 110 and 160 beats per minute. A fetal heart rate is considered abnormal if the heart rate is beyond the normal ranges or the rhythm is irregular. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ipej.2019.02.007DOI Listing
February 2019
1 Read

Pediatric Emergency Medicine Simulation Curriculum: Electrical Injury.

MedEdPORTAL 2018 Apr 27;14:10710. Epub 2018 Apr 27.

Assistant Professor, Department of Pediatrics, University of Washington School of Medicine.

Introduction: Electrical injuries are rare but potentially life-threatening medical emergencies that require providers to manage a critically ill patient while recognizing and treating the unique sequelae associated with the diagnosis. This simulation case is designed to give pediatric and emergency medicine residents, fellows, attendings, and nurses the opportunity to practice these skills in a realistic setting.

Methods: This simulation-based curriculum was designed for a high-fidelity mannequin in an emergency department resuscitation room but can be adapted to fit a variety of learning environments. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15766/mep_2374-8265.10710DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342442PMC

Kommerell Diverticulum: Right Aortic Arch with Anomalous Origin of Left Subclavian Artery and Duplicity of Right Vertebral Artery in a 16-Year-Old Girl.

Am J Case Rep 2019 Feb 21;20:228-232. Epub 2019 Feb 21.

Departmet of Catdiology, Universidade Nove de Julho, São Paulo, SP, Brazil.

BACKGROUND Kommerell diverticulum with a right-sided aortic arch is a rare congenital anatomical condition most often observed in adults. A possible etiology of the subclavian artery's anomalous origin would be an abnormality in regression of the fourth primitive aortic arch during embryonic development. CASE REPORT We report on the case of a 16-year-old female patient presenting with complaints of occasional tachycardia and mild non-specific dyspnea after anxiety crises. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.12659/AJCR.912053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394145PMC
February 2019
1 Read

Kratom exposures reported to United States poison control centers: 2011-2017.

Clin Toxicol (Phila) 2019 Feb 20:1-8. Epub 2019 Feb 20.

a Center for Injury Research and Policy , The Research Institute at Nationwide Children's Hospital , Columbus , OH , USA.

Context: Kratom, or Mitragyna speciosa, is a plant indigenous to Southeast Asia that has gained national attention in the United States for its increased use in the self-management of opioid withdrawal and pain, as well as for concerns about its safety.

Methods: This study analyzes exposures to kratom reported to poison control centers (PCCs) in the United States during 2011-2017 from the National Poison Data System (NPDS).

Discussion: From 2011 through 2017, 1807 kratom exposures were reported to United States PCCs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/15563650.2019.1569236DOI Listing
February 2019
5 Reads

Cardiac Arrest in the Pediatric Cardiac ICU: Is Medical Congenital Heart Disease a Predictor of Survival?

Pediatr Crit Care Med 2019 Mar;20(3):233-242

Section of Critical Care Medicine, Department of Pediatrics, Baylor College of Medicine, Houston, TX.

Objectives: Children with medical cardiac disease experience poorer survival to hospital discharge after cardiopulmonary arrest compared with children with surgical cardiac disease. Limited literature exists describing epidemiology and factors associated with mortality in this heterogeneous population. We aim to evaluate the clinical characteristics and outcomes after cardiopulmonary arrest in medical cardiac patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PCC.0000000000001810DOI Listing
March 2019
1 Read

Quinidine therapy and therapeutic drug monitoring in four patients with KCNT1 mutations.

Epileptic Disord 2019 Feb;21(1):48-54

National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders, Shizuoka.

Several recent studies have reported potassium sodium-activated channel subfamily T member 1 (KCNT1) mutations in epilepsy patients on quinidine therapy. The efficacy and safety of quinidine for epilepsy treatment, however, remains controversial. We herein report the cases of four patients with KCNT1 mutations treated with quinidine. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1684/epd.2019.1026DOI Listing
February 2019
4 Reads

Neonatal ventricular tachycardia: Adverse event possibly due to maternal ritodrine.

Pediatr Int 2019 Mar 7;61(3):298-299. Epub 2019 Feb 7.

Department of Pediatrics, Kagoshima University, Kagoshima, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ped.13763DOI Listing
March 2019
1 Read

Evaluation using a four-dimensional imaging tool before and after pulmonary valve replacement in a patient with tetralogy of Fallot: a case report.

J Med Case Rep 2019 Feb 5;13(1):30. Epub 2019 Feb 5.

Department of Pediatric Cardiovascular Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.

Background: Pulmonary regurgitation is a common complication after tetralogy of Fallot repair, resulting in right ventricular dysfunction, arrhythmia, and sudden death. However, the indications and optimal timing for pulmonary valve replacement are not fully known. We describe a case in which a four-dimensional imaging tool was useful in the decision to re-operate, thus resulting in decreased energy loss and improved right ventricular function after the re-operation for tetralogy of Fallot. Read More

View Article

Download full-text PDF

Source
https://jmedicalcasereports.biomedcentral.com/articles/10.11
Publisher Site
http://dx.doi.org/10.1186/s13256-018-1964-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362591PMC
February 2019
7 Reads

Ca-Binding Proteins of the EF-Hand Superfamily: Diagnostic and Prognostic Biomarkers and Novel Therapeutic Targets.

Authors:
Claus W Heizmann

Methods Mol Biol 2019 ;1929:157-186

Department of Pediatrics, Division of Clinical Chemistry and Biochemistry, University of Zürich, Zürich, Switzerland.

A multitude of Ca-sensor proteins containing the specific Ca-binding motif (helix-loop-helix, called EF-hand) are of major clinical relevance in a many human diseases. Measurements of troponin, the first intracellular Ca-sensor protein to be discovered, is nowadays the "gold standard" in the diagnosis of patients with acute coronary syndrome (ACS). Mutations have been identified in calmodulin and linked to inherited ventricular tachycardia and in patients affected by severe cardiac arrhythmias. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/978-1-4939-9030-6_11
Publisher Site
http://dx.doi.org/10.1007/978-1-4939-9030-6_11DOI Listing
January 2019
12 Reads

Successful radiofrequency catheter ablation of life-threatening atrial tachycardia in an infant with asplenia syndrome.

J Cardiol Cases 2019 Jan 14;19(1):1-4. Epub 2018 Sep 14.

Department of Pediatric Cardiology, Saitama Medical University International Medical Center, Saitama, Japan.

A 1-year-old infant with asplenia syndrome and congenital heart disease consisting of common atrium, common inlet left ventricle with a common atrio-ventricular (AV) valve, pulmonary atresia, and total anomalous pulmonary venous connection was admitted to our hospital for radiofrequency catheter ablation (RFCA) of supraventricular tachycardia (SVT) before total cavo-pulmonary connection. After antiarrhythmic medications were discontinued for RFCA, she suffered from SVT that resulted in the rapid deterioration of hemodynamic status. Antiarrhythmic medications and cardioversion were not effective in terminating SVT. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S18785409183007
Publisher Site
http://dx.doi.org/10.1016/j.jccase.2018.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342611PMC
January 2019
8 Reads

Challenging diagnosis of thyroid hormone resistance initially as Hashimoto's thyroiditis.

J Pediatr Endocrinol Metab 2019 Feb;32(2):203-206

Department of Pediatrics, Division of Pediatric Endocrinology, SUNY Downstate Medical Center, Brooklyn, NY, USA.

Background Resistance to thyroid hormone (RTH) commonly presents with goiter, attention deficit hyperactivity disorder (ADHD), short stature and tachycardia. However, due to its variable presentation with subtle clinical features, a third of the cases are mistreated, typically as hyperthyroidism. Case presentation A 15-year-old female with ADHD and oligomenorrhea was initially diagnosed as Hashimoto's thyroiditis but found to have a rare heterozygous mutation in c803 C>G (p Ala 268 Gly) in the THRβ gene, confirming resistance to thyroid hormone. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1515/jpem-2018-0284DOI Listing
February 2019
22 Reads

Sudden cardiac death in football players: Towards a new pre-participation algorithm.

Exp Ther Med 2019 Feb 30;17(2):1143-1148. Epub 2018 Nov 30.

Exercise Physiology and Sports Medicine Clinic, Center for Adolescent Medicine and UNESCO Chair on Adolescent Health Care, First Department of Pediatrics, Medical School, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, 11527 Athens, Greece.

Athletic pre-participation screening is essential for minimizing the risk for sudden cardiac death (SCD) in athletes participating in either competitive or leisure sporting activities. The primary causes of SCD in young athletes (<35 years of age) include hypertrophic cardiomyopathy, congenital anomalies of the coronary artery and arrhythmogenic right ventricular cardiomyopathy. Other abnormalities, such as malignant arrhythmia due to blunt trauma to the chest (commotio cordis), myocarditis, valvular disease, aortic rupture (in Marfan syndrome) and ion channelopathies (catecholaminergic polymorphic ventricular tachycardia, Brugada syndrome, long or short QT syndrome), also contribute to a lesser degree to SCD. Read More

View Article

Download full-text PDF

Source
http://www.spandidos-publications.com/10.3892/etm.2018.7041
Publisher Site
http://dx.doi.org/10.3892/etm.2018.7041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327574PMC
February 2019
20 Reads

Paediatric intensive care admissions during the 2015-2016 Queensland human parechovirus outbreak.

J Paediatr Child Health 2019 Jan 24. Epub 2019 Jan 24.

Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia.

Aim: The human parechovirus (HPeV) has emerged as a pathogen causing sepsis-like presentations in young infants, but there is a lack of data on HPeV presentations requiring intensive care support. We aimed to characterise the clinical presentation, disease severity, management and outcome of a population-based cohort of children with microbiologically confirmed HPeV infection requiring admission to paediatric intensive care units (PICUs) in Queensland, Australia during a recent outbreak.

Methods: This was a multicentre retrospective study of children admitted to PICU between 1 January 2015 and 31 December 2016 with confirmed HPeV infection. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/jpc.14336
Publisher Site
http://dx.doi.org/10.1111/jpc.14336DOI Listing
January 2019
15 Reads

Bioavailability of endotracheal epinephrine in an ovine model of neonatal resuscitation.

Early Hum Dev 2019 03 16;130:27-32. Epub 2019 Jan 16.

Department of Pediatrics, UC Davis School of Medicine, Sacramento, CA, United States of America.

Background: Distressed infants in the delivery room and those that have completed postnatal transition are both resuscitated according to established neonatal resuscitation guidelines, often with endotracheal (ET) epinephrine at the same dose. We hypothesized that ET epinephrine would have higher bioavailability in a post-transitional compared to transitioning newborn model due to absence of fetal lung liquid and intra-cardiac shunts.

Methods: 15 term fetal (transitioning newborn) and 6 postnatal lambs were asphyxiated by umbilical cord and ET tube occlusion respectively. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.earlhumdev.2019.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6402978PMC
March 2019
4 Reads

Association Between Time to Defibrillation and Survival in Pediatric In-Hospital Cardiac Arrest With a First Documented Shockable Rhythm.

JAMA Netw Open 2018 Sep 7;1(5):e182643. Epub 2018 Sep 7.

Center for Resuscitation Science, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts.

Importance: Delayed defibrillation (>2 minutes) in adult in-hospital cardiac arrest (IHCA) is associated with worse outcomes. Little is known about the timing and outcomes of defibrillation in pediatric IHCA.

Objective: To determine whether time to first defibrillation attempt in pediatric IHCA with a first documented shockable rhythm is associated with survival to hospital discharge. Read More

View Article

Download full-text PDF

Source
http://jamanetworkopen.jamanetwork.com/article.aspx?doi=10.1
Publisher Site
http://dx.doi.org/10.1001/jamanetworkopen.2018.2643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324599PMC
September 2018
11 Reads

Catecholaminergic Polymorphic Ventricular Tachycardia: The Cardiac Arrest Where Epinephrine Is Contraindicated.

Pediatr Crit Care Med 2019 Mar;20(3):262-268

Green Lane Paediatric and Congenital Cardiac Services, Starship Children's Hospital, Auckland, New Zealand.

Objectives: To raise awareness among pediatric intensive care specialists of catecholaminergic polymorphic ventricular tachycardia; an uncommon cause of polymorphic ventricular tachycardia and ventricular fibrillation arrest in children and young adults where epinephrine (adrenaline), even when given according to international protocols, can be counter-productive and life-threatening. We review three cases of cardiac arrest in children, later proven to be catecholaminergic polymorphic ventricular tachycardia related, where delay in recognition of this condition resulted in significantly longer resuscitation efforts, more interventions, and a longer time to return of spontaneous circulation.

Design: Retrospective case series. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PCC.0000000000001847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400445PMC
March 2019
19 Reads

Frequency Domain Indices of Heart Rate Variability are Useful for Differentiating Vasovagal Syncope and Postural Tachycardia Syndrome in Children.

J Pediatr 2019 Apr 7;207:59-63. Epub 2019 Jan 7.

Department of Pediatrics, Peking University First Hospital, Beijing, China; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China. Electronic address:

Objective: To explore the value of frequency domain indices of heart rate variability (HRV) in the differential diagnosis between pediatric vasovagal syncope and postural tachycardia syndrome (POTS).

Study Design: Eighty-five patients aged 7-16 years with either vasovagal syncope or POTS were enrolled in the experimental group; 18 healthy children served as controls. Holter electrocardiography was used to detect HRV frequency-domain indices in patients with vasovagal syncope, patients with POTS, and control subjects. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00223476183170
Publisher Site
http://dx.doi.org/10.1016/j.jpeds.2018.11.054DOI Listing
April 2019
15 Reads

Nonautoimmune congenital hyperthyroidism due to p.Asp633Glu mutation in the TSHR gene.

Ann Pediatr Endocrinol Metab 2018 Dec 31;23(4):235-239. Epub 2018 Dec 31.

Department of Pediatrics, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Korea.

Most cases of congenital hyperthyroidism are autoimmune forms caused by maternal thyroid stimulating antibodies. Nonautoimmune forms of congenital hyperthyroidism caused by activating mutations of the thyrotropin receptor (TSHR) gene are rare. A woman gave birth to a boy during an emergency cesarean section at 33 weeks of gestation due to fetal tachycardia. Read More

View Article

Download full-text PDF

Source
http://e-apem.org/journal/view.php?doi=10.6065/apem.2018.23.
Publisher Site
http://dx.doi.org/10.6065/apem.2018.23.4.235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312916PMC
December 2018
14 Reads

Phase I/II Trial of Electrophysiology-Guided Noninvasive Cardiac Radioablation for Ventricular Tachycardia.

Circulation 2019 Jan;139(3):313-321

Department of Internal Medicine, Cardiovascular Division (K.M.S.M., D.H.C., M.F., A.N., T.W.S., P.S.C.), Washington University, St Louis, MO.

Background: Case studies have suggested the efficacy of catheter-free, electrophysiology-guided noninvasive cardiac radioablation for ventricular tachycardia (VT) using stereotactic body radiation therapy, although prospective data are lacking.

Methods: We conducted a prospective phase I/II trial of noninvasive cardiac radioablation in adults with treatment-refractory episodes of VT or cardiomyopathy related to premature ventricular contractions (PVCs). Arrhythmogenic scar regions were targeted by combining noninvasive anatomic and electric cardiac imaging with a standard stereotactic body radiation therapy workflow followed by delivery of a single fraction of 25 Gy to the target. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.038261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331281PMC
January 2019
5 Reads

2018 American Heart Association Focused Update on Pediatric Advanced Life Support: An Update to the American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.

Circulation 2018 Dec;138(23):e731-e739

This 2018 American Heart Association focused update on pediatric advanced life support guidelines for cardiopulmonary resuscitation and emergency cardiovascular care follows the 2018 evidence review performed by the Pediatric Task Force of the International Liaison Committee on Resuscitation. It aligns with the International Liaison Committee on Resuscitation's continuous evidence review process, and updates are published when the group completes a literature review based on new published evidence. This update provides the evidence review and treatment recommendation for antiarrhythmic drug therapy in pediatric shock-refractory ventricular fibrillation/pulseless ventricular tachycardia cardiac arrest. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIR.0000000000000612DOI Listing
December 2018
2 Reads

Prognostic Significance of PR Interval Prolongation in Adult Patients With Total Correction of Tetralogy of Fallot.

Circ Arrhythm Electrophysiol 2018 Nov;11(11):e006234

Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan (Y.K., K. Fukuda, M.N., Y.H., K. Fukasawa, T.C., K.M., S.T., H.S.).

Background: Several studies have demonstrated the importance of mechanoelectrical interaction in patients with surgically corrected tetralogy of Fallot. However, the significance of atrioventricular conduction disturbance, that is PR interval prolongation, on adverse cardiac events in those patients remains to be elucidated.

Methods: We examined electrocardiograms at baseline and their temporal change in a total of 176 patients with repaired tetralogy of Fallot (49% men; median age, 17. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.118.006234DOI Listing
November 2018
2 Reads

Plasma Homocysteine Level in Children With Postural Tachycardia Syndrome.

Front Pediatr 2018 3;6:375. Epub 2018 Dec 3.

Department of Pediatrics, Peking University First Hospital, Beijing, China.

The study was designed to evaluate the changes of plasma homocysteine (Hcy) level in children with postural tachycardia syndrome (POTS) and explore its significance. A total of 65 subjects were recruited in our study, of whom 35 children were in the POTS group and 30 healthy children were in the control group. Plasma Hcy levels were determined in all subjects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fped.2018.00375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287046PMC
December 2018
1 Read

Contemporary Outcomes of Pediatric Restrictive Cardiomyopathy: A Single-Center Experience.

Pediatr Cardiol 2019 Apr 12;40(4):694-704. Epub 2018 Dec 12.

Cincinnati Children's Hospital Medical Center, Heart Institute, Cincinnati, OH, USA.

Background: Pediatric restrictive cardiomyopathy (RCM) has high mortality in historical cohorts, and traditional management often involves early referral for heart transplantation (HTx). This study sought to determine outcomes of pediatric RCM at a center that has favored medical management over early listing for HTx.

Methods: All patients (N = 43) with pure RCM phenotype (RCM, N = 26) and hypertrophic cardiomyopathy with restrictive physiology (RCM/HCM, N = 17) managed at our center over a 15-year period were investigated. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00246-018-2043-0DOI Listing
April 2019
1 Read

Incidence and effect of early postoperative ventricular arrhythmias after congenital heart surgery.

Heart Rhythm 2018 Dec 5. Epub 2018 Dec 5.

Department of Pediatrics, Thomas P. Graham Jr. Division of Cardiology, Vanderbilt University Medical Center, Nashville, Tennessee.

Background: Postoperative arrhythmias after pediatric congenital heart disease (CHD) surgery are a known cause of morbidity and are associated with mortality. A comprehensive evaluation of early postoperative ventricular arrhythmias (VAs) after CHD surgery has not been reported.

Objectives: We sought to determine the incidence of in-hospital VAs after CHD surgery and assess the clinical relevance of this arrhythmia during the postoperative hospital course. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2018.11.032DOI Listing
December 2018
7 Reads

Safety of Sports for Young Patients With Implantable Cardioverter-Defibrillators.

Circ Arrhythm Electrophysiol 2018 Nov;11(11):e006305

Yale University School of Medicine, New Haven, CT (J.D., C.B., L.S., F.L., R.J.L.).

Background: Despite safety concerns, many young patients with implantable cardioverter-defibrillators (ICDs) participate in sports. We undertook a prospective, multinational registry to determine the incidence of serious adverse events because of sports participation. The primary end points were death or resuscitated arrest during sports or injury during sports because of arrhythmia or shock. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCEP.118.006305DOI Listing
November 2018
16 Reads

Postural orthostatic tachycardia syndrome (POTS) in teens: A guide for behavior change to manage symptoms.

Pacing Clin Electrophysiol 2019 02 18;42(2):283-286. Epub 2018 Dec 18.

Department of Pediatrics, Baylor College of Medicine, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pace.13571DOI Listing
February 2019
28 Reads

Low Sensitivity of Abbreviated Tilt Table Testing for Diagnosing Postural Tachycardia Syndrome in Adults With ME/CFS.

Front Pediatr 2018 16;6:349. Epub 2018 Nov 16.

Stichting CardioZorg, Hoofddorp, Netherlands.

Orthostatic intolerance is common among individuals with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). In some ME/CFS case definitions, orthostatic intolerance is considered a core feature of the disorder. Some studies have employed tilt table tests lasting 2-5 min to diagnose one common form of orthostatic intolerance, postural tachycardia syndrome (POTS). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fped.2018.00349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250822PMC
November 2018
2 Reads

Lassa fever outbreak in adolescents in North Central Nigeria: report of cases.

J Virus Erad 2018 Oct 1;4(4):225-227. Epub 2018 Oct 1.

Department of Paediatrics, Jos university Teaching Hospital, Jos, Nigeria.

Background: Lassa fever (LF) is a viral haemorrhagic fever endemic to West Africa. The clinical presentation and course is variable, making diagnosis difficult.

Aim: To report the outbreak and identify the common clinical presentations of LF in paediatric patients in Jos, Plateau State, North Central, Nigeria. Read More

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248838PMC
October 2018
3 Reads