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    177 results match your criteria Pediatrics Scarlet Fever

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    Into Darkness and Silence: What Caused Helen Keller's Deafblindness?
    Clin Infect Dis 2018 May 5. Epub 2018 May 5.
    Department of Pediatrics, University of Michigan Medical School, Ann Arbor, Michigan.
    In 1882, at 19 months of age, Helen Keller developed a febrile illness that left her both deaf and blind. Historical biographies attribute the illness to rubella, scarlet fever, encephalitis, or meningitis. This analysis of her illness suggests she likely had bacterial meningitis, caused by N. Read More

    Identification and Characterization of Fluoroquinolone Non-susceptible Clones Harboring Tetracycline and Macrolide Resistance in Shanghai, China.
    Front Microbiol 2018 23;9:542. Epub 2018 Mar 23.
    Department of Microbiology, Shanghai Municipal Center for Disease Control and Prevention, Shanghai, China.
    , also known as group A (GAS), is one of the top 10 infectious causes of death worldwide. Macrolide and tetracycline resistant GAS has emerged as a major health concern in China coinciding with an ongoing scarlet fever epidemic. Furthermore, increasing rates of fluoroquinolone (FQ) non-susceptibility within GAS from geographical regions outside of China has also been reported. Read More

    The Role of Childhood Infections and Immunizations on Childhood Rhabdomyosarcoma: A Report From the Children's Oncology Group.
    Pediatr Blood Cancer 2016 09 19;63(9):1557-62. Epub 2016 May 19.
    Department of Pediatrics, Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas.
    Background: Rhabdomyosarcoma (RMS) is a rare, highly malignant tumor arising from primitive mesenchymal cells that differentiate into skeletal muscle. Relatively little is known about RMS susceptibility. Based on growing evidence regarding the role of early immunologic challenges on RMS development, we evaluated the role of infections and immunizations on this clinically significant pediatric malignancy. Read More

    Distribution of emm types among group A Streptococcus isolates from children in Korea.
    Diagn Microbiol Infect Dis 2015 May 15;82(1):26-31. Epub 2015 Jan 15.
    Department of Pediatrics, Seoul National University Children's Hospital, Seoul, Republic of Korea; Department of Pediatrics, Seoul National University College of Medicine, Seoul, Republic of Korea.
    We analyzed 155 clinical group A Streptococcus (GAS) isolates from children at the Seoul National University Children's Hospital between 1991 and 2012 and the Seoul National University Bundang Hospital between 2006 and 2012. The erythromycin resistance rate was 10.3% (16/155), and all isolates during the recent 3 years were susceptible to erythromycin. Read More

    Erythromycin-resistant genes in group A β-haemolytic Streptococci in Chengdu, Southwestern China.
    Indian J Med Microbiol 2014 Jul-Sep;32(3):290-3
    Department of Pediatrics, West China Second Hospital, Sichuan University, Chengdu, Sichuan, The People's Republic of China, .
    Context: The management of Group A β-haemolytic Streptococci (Streptococcus pyogenes or GAS) infection include the use of penicillins, cephalosporins or macrolides for treatment. A general increase in macrolides resistance in GAS has been observed in recent years. Differences in rates of resistance to these agents have existed according to geographical location and investigators. Read More

    The trend of macrolide resistance and emm types of group A streptococci from children at a medical center in southern Taiwan.
    J Microbiol Immunol Infect 2015 Apr 3;48(2):160-7. Epub 2013 Oct 3.
    Department of Pediatrics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Center of Infectious Disease and Signaling Research, National Cheng Kung University, Tainan, Taiwan. Electronic address:
    Background: Group A streptococcus (GAS) is a common pathogen in children. Macrolide resistance in GAS has been described worldwide. The aims of this study are to analyze macrolide resistance of GAS isolates in southern Taiwan and to clarify the relationship of emm typing and macrolide resistance in the past decade. Read More

    Molecular characterization of Group A streptococcal isolates causing scarlet fever and pharyngitis among young children: a retrospective study from a northern Taiwan medical center.
    J Microbiol Immunol Infect 2014 Aug 30;47(4):304-10. Epub 2013 Apr 30.
    Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC. Electronic address:
    Background/purpose: Little information is available on the differences in frequency of pyrogenic exotoxin genes between strains of group A streptococci that cause scarlet fever and those that cause pharyngotonsillitis in children in Taiwan. This study retrospectively monitored the presence of pyrogenic exotoxin genes, the emm typing, and the susceptibility of macrolide drugs in Streptococcus pyogenes isolated from children diagnosed with scarlet fever and pharyngotonsillitis in northern Taiwan.

    Materials And Methods: Isolates of S. Read More

    Kawasaki disease: laboratory findings and an immunopathogenesis on the premise of a "protein homeostasis system".
    Yonsei Med J 2012 Mar;53(2):262-75
    Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea.
    Kawasaki disease (KD) is a self-limited systemic inflammatory illness, and coronary artery lesions (CALs) are a major complication determining the prognosis of the disease. Epidemiologic studies in Asian children suggest that the etiologic agent(s) of KD may be associated with environmental changes. Laboratory findings are useful for the diagnosis of incomplete KD, and they can guide the next-step in treatment of initial intravenous immunoglobulin non-responders. Read More

    Scarlet fever caused by community-associated methicillin-resistant Staphylococcus aureus.
    Indian Pediatr 2011 Jul;48(7):563-5
    Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, No. 325 Cheng-Kung Road, Nei-hu, Taipei, Taiwan.
    We describe a previously healthy 2.5-year-old boy with staphylococcal scarlet fever associated with acute suppurative otitis media due to community-associated methicillin-resistant Staphylococcus aureus. The patient was successfully treated by spontaneous drainage in combination with trimethoprim-sulfamethoxazole therapy. Read More

    [Differences in antibiotic prescribing between general practitioners and pediatricians in Hesse, Germany].
    Dtsch Med Wochenschr 2010 Sep 7;135(37):1792-7. Epub 2010 Sep 7.
    PMV forschungsgruppe, Klinik und Poliklinik für Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Universität zu Köln, Köln, Germany.
    Background: A careful consideration of antibiotic prescription is necessary due to emerging antibiotic resistance. Differences in prescription rates between physician groups have only rarely been examined. We compared the prescription of antibiotics for systemic use in children between pediatricians and general practitioners (GPs). Read More

    Panton-Valentine leukocidin is associated with exacerbated skin manifestations and inflammatory response in children with community-associated staphylococcal scarlet fever.
    Clin Infect Dis 2009 Oct;49(7):e69-75
    Department of Pediatrics, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
    Background: Staphylococcal scarlet fever (SSF), a rare disease, was first described in 1900. The clinical features and outcomes in children with SSF caused by Panton-Valentine leukocidin (PVL)-positive and PVL-negative Staphylococcus aureus strains have not been compared prospectively.

    Methods: The demographic data, selected clinical features, laboratory values, and outcomes for 49 consecutive children with community-acquired S. Read More

    Stevens-Johnson syndrome and toxic epidermal necrolysis: consequence of treatment of an emerging pathogen.
    Pediatr Emerg Care 2009 Aug;25(8):519-22
    Pediatrics, University of Pennsylvania School of Medicine, Division of Emergency Medicine, Children's Hospital of Philadelphia, 34th St and Civic Center Blvd, Philadelphia, PA 19104, USA.
    We report a case of Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) secondary to trimethoprim-sulfamethoxazole (TMP-Sx) therapy for presumed community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection. Although the association between SJS/TEN and the sulfonamide class of antibiotics is well established, the increasing prevalence of CA-MRSA has left practitioners with limited regimens to effectively treat skin and soft tissue infections (SSTIs) in the outpatient setting. In the case of SSTIs, alternative treatment of these infections should be considered, especially when the bacterial pathogen is unknown. Read More

    Circulating serotypes and antimicrobial sensitivity of Streptococcus pyogenes isolates from children in Cyprus.
    Clin Microbiol Infect 2007 Jun 22;13(6):645-7. Epub 2007 Mar 22.
    Infectious Diseases Research Laboratory, Department of Pediatrics, Archbishop Makarios Hospital, Nicosia, Cyprus.
    The most common T-serotypes among group A streptococci (n = 88) isolated from pharyngeal samples of children referred to a tertiary hospital in Cyprus for pharyngitis or scarlet fever during a 14-month period (2003-2004) were T28 (25%), T8/25/Imp19 (22.7%) and T12 (9.1%). Read More

    [Exanthema as a main symptom in the febrile child].
    Ther Umsch 2005 Aug;62(8):549-55
    Päidiatrische Infektiologie, Universitätsspital Bern, Inselspital, Bern.
    Distinguishing in febrile children between harmless rashes and those, which require specific action, is a common problem in pediatric primary care. Major exanthematous diseases necessitating emergency hospitalization include invasive meningococcal disease and rarely gram-negative septicaemia caused by other pathogens, staphylococcal and streptococcal toxic shock syndrome, endocarditis, fever and rash in travellers returning from tropical countries and drug hypersensitivity syndrome. Therapeutic intervention is also necessary in patients with scarlet fever, rheumatic fever, varicella in postpuberal and immunocompromised individuals, in Kawasaki's disease, in Still's disease and in other non-infectious, inflammatory diseases (e. Read More

    Enterotoxin B is the predominant toxin involved in staphylococcal scarlet fever in Taiwan.
    Clin Infect Dis 2004 May 29;38(10):1498-502. Epub 2004 Apr 29.
    Department of Pediatrics, Tri-Service General Hospital, Taipei, Taiwan.
    This study retrospectively reviewed all pediatric cases of staphylococcal scarlet fever (SSF) that occurred during a 10-year period in a 1400-bed tertiary medical center in northern Taiwan. All 20 cases of SSF occurred in previously healthy individuals. Skin and soft-tissue infections predominated among children from whom Staphylococcus aureus was isolated. Read More

    Varicella complicated by scarlet fever.
    Indian Pediatr 2003 Oct;40(10):1002-4
    Department of Pediatrics, Duzce School of Medicine, Abant Izzet Baysal University, Turkey.
    We report a 3-year-old boy with varicella complicated by cellulitis and scarlet fever. He developed a typical rash of scarlet fever following the onset of varicella. Streptococcus pyogenes was isolated from the ulcers due to varicella. Read More

    [The relationship between insulin-dependent diabetes mellitus and acute infections in children].
    Endokrynol Diabetol Chor Przemiany Materii Wieku Rozw 2003 ;9(2):73-6
    Department of Pediatrics, Grodno State Medical University, Belarus.
    The morbidity of insulin-dependent diabetes mellitus (IDDM) in children develops not evenly. Epidemiological leaps are periodically registered. This character of dynamics suggests the existence of environmental factors having the influence on the IDDM morbidity. Read More

    Streptococcal exanthem in a blaschkolinear pattern: clinical evidence for genetic mosaicism in hypomelanosis of ito.
    Pediatr Dermatol 2002 Sep-Oct;19(5):423-5
    Departments of Dermatology, National Institute of Pediatrics of Mexico, Mexico City, Mexico.
    Due to the presence of two different clones of cells in early embryogenesis, numerous congenital and acquired dermatoses have a linear distribution following the lines of Blaschko. Acquired inflammatory skin diseases are rarely observed in linear patterns. Our patient was born with macrocephaly, left eye glaucoma, and a left facial and contralateral corporal hemihypertrophy, cerebral dysgenesis, and skeletal abnormalities. Read More

    Kawasaki disease before kawasaki at Tokyo university hospital.
    Pediatrics 2002 Aug;110(2 Pt 1):e17
    Department of Pediatrics, Sanno Hospital, Tokyo, Japan.
    Objective: Kawasaki disease (KD) was first reported by Tomisaku Kawasaki in 1967 in Japan. Large-scale nationwide epidemiologic surveys have been conducted continuously by the Japan Kawasaki Disease Research Committee; however, there were very few reports of KD before 1967. This study was performed to clarify when KD appeared in Japan. Read More

    [Infectious skin diseases in childhood. 1: Bacteria and fungi].
    MMW Fortschr Med 2002 Jun;144(25):24-8, 30
    MMW-Stipendiat, Forschungsschwerpunkt Genodermatosen, Klinik u. Poliklinik für Dermatologie u. Allergologie der LMU München.
    Infections may lead to a multitude of pathological skin alterations, and represent the most common diseases in pediatric dermatology. A prerequisite for successful treatment is an accurate diagnosis based on the medical history, clinical presentation and the culture of pathogens. Of importance among the bacterial skin diseases in pediatrics are impetigo, scarlet fever, borreliosis and cat-scratch fever. Read More

    Staphylococcal scalded-skin syndrome in a very low birth weight premature infant.
    Pediatrics 2001 Jul;108(1):E16
    Department of Neonatology, Rambam Medical Center and Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
    Exfoliative skin diseases are rare in neonates. When caused by coagulase-positive Staphylococcus aureus, scalded-skin diseases such as staphylococcal scalded-skin syndrome (SSSS), bullous impetigo, and staphylococcal scarlet fever may develop. These diseases might cause significant complications and mortality. Read More

    The fourth disease, 1900-2000.
    Lancet 2001 Jan;357(9252):299-301
    Department of Pediatrics, West Virginia University School of Medicine, USA.
    Measles and scarlet fever were differentiated from one another in the 17th century. Rubella was accepted as the third distinct paediatric exanthem in 1881. Nil Filatow in 1885 and Clement Dukes in 1894 described two distinct forms of rubella, and in 1900 Dukes proposed that one of these forms of rubella was a separate entity which he called the fourth disease. Read More

    [Estimate of underreporting of infectious diseases through a sentinel network of pediatricinas in the area of local health unit of Florence].
    Epidemiol Prev 2000 Sep-Oct;24(5):224-7
    Scuola di specializzazione in Igiene e medicina preventiva, Università di Firenze.
    The aim of this study was to evaluate the underreporting of some infectious diseases in the pediatric population in the Local Health Unit of Florence in the period 15.09.1997-14. Read More

    Kawasaki disease: a diagnostic challenge.
    S D J Med 2000 Dec;53(12):527-30
    Department of Pediatrics, University of South Dakota School of Medicine, Sioux Falls, SD, USA.
    Kawasaki disease (KD) is an acute, self-limited, febrile, multi-system vasculitis that predominantly affects the the pediatric population, and is the leading cause of acquired heart disease in children. No etiologic agent for the disease has been identified, there are no diagnostic tests available, and the diagnosis is established by fulfilling a defined set of clinical criteria. We report on a 9-year-old boy who presented initially with symptoms felt to represent a streptococcal infection. Read More

    Kawasaki disease: A brief history.
    Pediatrics 2000 Aug;106(2):E27
    Department of Pediatrics, University of California San Diego, La Jolla, California 92093-0830, USA.
    Tomisaku Kawasaki published the first English-language report of 50 patients with Kawasaki disease (KD) in 1974. Since that time, KD has become the leading cause of acquired heart disease among children in North America and Japan. Although an infectious agent is suspected, the cause remains unknown. Read More

    Streptococcus mitis septicaemia and hepatitis.
    Scand J Infect Dis 2000 ;32(2):214-5
    Department of Paediatrics, University of Ioannina, Greece.
    The case of an otherwise well 9-y-old boy with fever, papular rash, jaundice and impaired liver function is presented. Streptococcus mitis sensitive to penicillin grew in blood culture. The boy had an excellent outcome. Read More

    Annual summary of vital statistics: trends in the health of Americans during the 20th century.
    Pediatrics 2000 Dec;106(6):1307-17
    Department of Population and Family Health Sciences, Johns Hopkins School of Public Health, Baltimore, Maryland, USA.
    The overall improvement in the health of Americans over the 20th century is best exemplified by dramatic changes in 2 trends: 1) the age-adjusted death rate declined by about 74%, while 2) life expectancy increased 56%. Leading causes of death shifted from infectious to chronic diseases. In 1900, infectious respiratory diseases accounted for nearly a quarter of all deaths. Read More

    [Clinical evaluation of a new macrolide antibiotic, azithromycin, in the pediatric field].
    Jpn J Antibiot 1997 Mar;50(3):265-71
    Department of Pediatrics, Teikyo University Ichihara Hospital.
    Azithromycin (AZM) preparations in fine granules and capsules were evaluated in 36 pediatric patients with various infections. In patients with pneumonia caused by Moraxella catarrhalis, Haemophilus influenzae or Mycoplasma pneumoniae, bronchitis, pharyngitis, scarlet fever, whooping cough, or campylobacter enteritis, AZM was found effective in 94.4% (34/36). Read More

    Decrease in the concentrations of transforming growth factor-beta 1 in the sera of patients with Kawasaki disease.
    Scand J Rheumatol 1997 ;26(4):314-7
    Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan.
    Kawasaki disease (KD) is one of the most important forms of vasculitis, and is characterized by the initiation of a proinflammatory cytokine cascade. To further characterize the immunological profile of KD, we measured the serum levels of transforming growth factor-beta 1 (TGF-beta 1) as a regulatory cytokine. We determined the concentration of TGF-beta 1 in the sera of the patients with KD, anaphylactoid purpura (AP), and scarlet fever, using a sandwich enzyme linked immunosorbent assay. Read More

    [Therapeutic efficacy of azithromycin in pediatrics].
    Jpn J Antibiot 1996 Oct;49(10):926-31
    Department of Pediatrics, Kobe Central Municipal Hospital.
    Azithromycin (AZM), a newly developed azalide antibiotic, was administered at a standard dose of 10 mg/kg once daily for 3 days to pediatric patients with bacterial infections and the therapeutic efficacy of AZM was investigated. 1. A total of 12 patients with the following diseases was evaluated: pharyngitis in two, tonsillitis in four, bronchitis in one, Mycoplasma pneumonia in one, scarlet fever in two and enteritis in two. Read More

    [Clinical evaluation of azithromycin in pediatric infections].
    Jpn J Antibiot 1996 Oct;49(10):917-25
    Department of Pediatrics, Osaka Medical College.
    Azithromycin (AZM) was studied for its clinical efficacy in pediatric infections. The study on AZM was carried out in 43 patients whose diagnoses were given as follows: pharyngitis in five cases, tonsillitis in one, bronchitis in four, pneumonia in four, Mycoplasma pneumonia in 14, scarlet fever in nine, impetigo in four, pyodermia in one and Campylobacter enteritis in one. The patients received AZM once daily at 1. Read More

    [Bacteriological, pharmacokinetic and clinical evaluation of azithromycin in the pediatric field].
    Jpn J Antibiot 1996 Oct;49(10):899-916
    Department of Pediatrics, Yamato City Hospital.
    Azithromycin (AZM), a new macrolide antibiotic, in fine granules and in capsules was studied for pharmacokinetic and clinical evaluation in the pediatric patients. Antibacterial activity of AZM against 43 clinical isolates: AZM exhibited slightly lower activity against Gram-positive bacteria and 2-8-fold higher activity against Gram-negative bacteria than erythromycin or clarithromycin. Plasma or urine samples were collected from eight patients receiving the drug in fine granular form, and two patients receiving it in capsules for the determination of drug levels. Read More

    Soluble CD23 antigen in Kawasaki disease and other acute febrile illnesses.
    Eur J Pediatr 1995 Oct;154(10):826-9
    Department of Paediatrics, Juntendo University School of Medicine, Tokyo, Japan.
    Kawasaki disease (KD) is an acute febrile illness of early childhood. Although the epidemiology of KD suggests an infectious agent, the cause still remains unknown. Intense immune activation during the acute disease has been well documented. Read More

    [Clinical studies on SY5555 in pediatrics].
    Jpn J Antibiot 1995 Feb;48(2):220-8
    Department of Pediatrics, Takamatsu Red Cross Hospital.
    SY5555 in dry syrup (powder which is dissolved before use) or tablet form was given orally to 21 children with acute bacterial infections including 4 with acute pharyngitis, 5 with acute tonsillitis, 7 with acute bronchitis, 2 with acute gastroenteritis, 1 each with scarlet fever, acute lymphadenitis and urinary tract infection. Good to excellent clinical responses were obtained in all of the 21 patients and 8 of 11 strains found as causative organisms in these cases were eradicated and 3 strains were decreased. Loose stools were observed in 3 cases and eosinophilia was observed in 1 case. Read More

    [A clinical evaluation of SY5555 in the treatment of pediatric infections].
    Jpn J Antibiot 1995 Feb;48(2):210-9
    Department of Pediatrics, Kagawa Children's Hospital National Sanatorium.
    1. SY5555 dry syrup (powder which is dissolved before use) was administered to 25 patients with bacterial infections (6 cases of bronchitis, 2 cases of bronchopneumonia, 1 case of pertussis, 3 cases of scarlet fever, 5 cases of tonsillitis, 3 cases of urinary tract infections, 2 cases of staphylococcal scalded skin syndrome, 1 case of impetigo, 2 cases of purulent lymphadenitis). 2. Read More

    [Clinical study of SY5555 dry syrup in the pediatric field].
    Jpn J Antibiot 1995 Feb;48(2):205-9
    Department of Pediatrics, Kobe City General Hospital.
    SY5555 dry syrup (powder to be dissolved before use) was clinically used in pediatric patients. The following results were obtained: 1. The subjects were 6 pediatric patients including 1 case each with pharyngitis, tonsillitis, lacunar tonsillitis and impetigo contagiosa and 2 cases with scarlet fever. Read More

    [Bacteriological and clinical studies of SY5555 in pediatric field].
    Jpn J Antibiot 1995 Feb;48(2):191-9
    Department of Pediatrics, Osaka Medical College.
    Clinical studies were carried out on SY5555, a new oral penem, in the field of pediatrics. The results obtained are summarized below. The clinical efficacies were examined in a total 31 patients consisting of 4 patients with pharyngitis, 10 with purulent tonsillitis, 4 with scarlet fever, 7 with impetigo, one with balanitis, one with cellulitis and 4 with UTI. Read More

    [Bacteriological, pharmacokinetic and clinical studies of SY5555 dry syrup in the pediatric field].
    Jpn J Antibiot 1995 Jan;48(1):71-91
    Department of Pediatrics, Yamanashi Red Cross Hospital.
    Bacteriological, pharmacokinetic and clinical studies on SY5555 dry syrup (powder which is dissolved before use), a new penem antibiotic for oral use, were performed. The following results were obtained. 1. Read More

    [Clinical studies on SY5555 in pediatric infections].
    Jpn J Antibiot 1995 Jan;48(1):49-70
    Department of Pediatrics, Oguchi Higashi General Hospital.
    Pharmacokinetic and clinical studies on SY5555, a new oral penem antibiotics, were performed in pediatric infections and the following results were obtained. 1. Pharmacokinetics studies Pharmacokinetics of SY5555 was studied in 5 children (5y1m-10y11m) using doses of 5 mg/kg (n = 3) and 10 mg/kg (n = 2). Read More

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