265 results match your criteria Pediatrics Pyloric Stenosis


Caterpillar Sign in an Infant with Hypertrophic Pyloric Stenosis.

J Pediatr 2019 Feb 2. Epub 2019 Feb 2.

Department of General Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jpeds.2018.12.058DOI Listing
February 2019
1 Read

Presentation and outcomes in hypertrophic pyloric stenosis: An 11-year review.

J Paediatr Child Health 2019 Jan 24. Epub 2019 Jan 24.

Department of Paediatric Surgery, Monash Children's Hospital, Melbourne, Victoria, Australia.

Aim: To evaluate the trend in presentation and postoperative outcomes of infants with hypertrophic pyloric stenosis (HPS) over the last decade.

Methods: This was a multicentre retrospective study in two tertiary paediatric centres between 2005 and 2015 inclusive. Participants included 626 infants who underwent a pyloromyotomy for HPS. Read More

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http://doi.wiley.com/10.1111/jpc.14372
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http://dx.doi.org/10.1111/jpc.14372DOI Listing
January 2019
5 Reads

Bart's Syndrome with Novel Frameshift Mutations in the COL7A1 Gene.

Fetal Pediatr Pathol 2018 Dec 7:1-8. Epub 2018 Dec 7.

c Department of Dermatology , Pusan National University Yangsan Hospital , Yangsan , Republic of Korea.

Introduction: Bart's syndrome, a hereditary mechanobullous disorder characterized by aplasia cutis congenita (ACC) with epidermolysis bullosa (EB), has not been genotyped frequently.

Case Report: A full-term female neonate had well-demarcated absence of skin on both legs at birth, with blisters and erosive patches developing immediately after birth. Electron microscopy showed blister formation under the lamina densa layer. Read More

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http://dx.doi.org/10.1080/15513815.2018.1543370DOI Listing
December 2018
1 Read

Effects of Hospital Volume on Patient Outcomes and Costs in Infants With Pyloric Stenosis.

J Surg Res 2019 Jan 17;233:65-73. Epub 2018 Aug 17.

Department of Surgery, Harbor-UCLA Medical Center, Torrance, California; Division of Pediatric Surgery, Department of Surgery, David Geffen School of Medicine, UCLA, Los Angeles, California; Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, California; Los Angeles Biomedical Research Institute, Torrance, California. Electronic address:

Background: There is a well-established relationship between surgical volume and outcomes after complex pediatric operations. However, this relationship remains unclear for common pediatric procedures. The aim of our study was to investigate the effect of hospital volume on outcomes after hypertrophic pyloric stenosis (HPS). Read More

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http://dx.doi.org/10.1016/j.jss.2018.07.033DOI Listing
January 2019
3 Reads

Endoscopic Balloon Dilation for Treatment of Congenital Antral Web.

Pediatr Gastroenterol Hepatol Nutr 2018 Oct 10;21(4):351-354. Epub 2018 Oct 10.

Pediatric Gastroenterology, Johns Hopkins All Children's Hospital, St. Petersburg, FL, United States.

Congenital antral webs are a rare but relevant cause of gastric outlet obstruction in infants and children. The condition may lead to feeding refusal, vomiting, and poor growth. Due to the relative rarity of the disease, cases of congenital antral web are frequently misdiagnosed or diagnosed with significant delay as physicians favorably pursue diagnoses of pyloric stenosis and gastric ulcer disease, which are more prevalent. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.5223/pghn.2018.2
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http://dx.doi.org/10.5223/pghn.2018.21.4.351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182476PMC
October 2018
18 Reads

Impact of a multimedia teaching tool on parental anxiety and knowledge during the informed consent process.

Pediatr Surg Int 2018 Dec 25;34(12):1345-1352. Epub 2018 Sep 25.

Department of Surgery and Pediatrics, Children's Foundation Research Institute, Le Bonheur Children's Hospital, University of Tennessee Health Sciences Center, 49 North Dunlap, Suite 266, Memphis, TN, 38105, USA.

Purpose: Before performing a surgical procedure, informed consent (IC) is obtained. Parents may exhibit anxiety and/or a desire for more knowledge during the IC process for their child. The purpose of this study was to measure the impact of a multimedia intervention (MMI) versus conventional discussion on parental understanding and anxiety during the IC process for infants undergoing surgery for hypertrophic pyloric stenosis. Read More

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http://dx.doi.org/10.1007/s00383-018-4352-zDOI Listing
December 2018
2 Reads

Retrospective Cohort Study on the Optimal Timing of Orogastric Tube/Nasogastric Tube Insertion in Infants With Pyloric Stenosis.

Anesth Analg 2018 Sep 18. Epub 2018 Sep 18.

From the Department of Anesthesiology and Perioperative Medicine, Division of Pediatric Anesthesiology, David Geffen School of Medicine at University of California, Los Angeles, California.

Background: Hypertrophic pyloric stenosis in infants can cause a buildup of gastric contents. Orogastric tubes (OGTs) or nasogastric tubes (NGTs) are often placed in patients with pyloric stenosis before surgical management to prevent aspiration. However, exacerbation of gastric losses may lead to electrolyte abnormalities that can delay surgery, and placement has been associated with increased risk of postoperative emesis. Read More

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http://dx.doi.org/10.1213/ANE.0000000000003805DOI Listing
September 2018
10 Reads

Hypertrophic pyloric stenosis following persistent pulmonary hypertension of the newborn: a case report and literature review.

BMC Pediatr 2018 Sep 3;18(1):290. Epub 2018 Sep 3.

Department of Pediatrics, Hamamatsu University School of Medicine, 1 - 20 - 1 Handayama, Hamamatsu, Shizuoka, 431 - 3192, Japan.

Background: Although persistent pulmonary hypertension of the newborn (PPHN) and infantile hypertrophic pyloric stenosis (HPS) are both well-known diseases that occur in early infancy, PPHN complicated by HPS is rare. As nitric oxide (NO) is an important mediator of biological functions, on both the vascular endothelium and smooth muscle cells, the decreased production of NO might play a role in the pathogenesis of both PPHN and HPS. We present the case of a neonate who developed HPS following PPHN, including a detailed review on research published to date, and we discuss the pathogenesis of PPHN and HPS. Read More

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http://dx.doi.org/10.1186/s12887-018-1270-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122549PMC
September 2018
4 Reads

Diffuse infantile hepatic haemangioma-how to manage an incidental but potentially lethal finding.

Oxf Med Case Reports 2018 Aug 21;2018(8):omy054. Epub 2018 Aug 21.

Paediatrics Department, Hospital Dr. Nélio Mendonça, Funchal, Portugal.

Infantile hepatic haemangioma (IHH) is a rare vascular tumour that is potentially lethal due to its associated complications, including heart failure, hepatic failure, hypothyroidism and abdominal compartment syndrome. The authors report a case of an asymptomatic diffuse IHH in a newborn male, which was presented as an incidental finding at the time that the patient was diagnosed with pyloric stenosis. The patient was treated with increasing doses of propranolol that were well tolerated. Read More

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http://dx.doi.org/10.1093/omcr/omy054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105109PMC
August 2018
3 Reads

Perinatal findings in a patient with a novel large chromosome 19p deletion.

Clin Case Rep 2018 Aug 21;6(8):1525-1530. Epub 2018 Jun 21.

Division of Maternal Fetal Medicine Sibley Memorial Hospital Washington DC USA.

We describe the prenatal and postnatal course of an infant with a large 19p deletion. Cases such as ours will improve the knowledge of specific gene functions for every medical specialist. The goal is to allow for a more rapid diagnosis, accurate prognosis and to decrease the likelihood of complications. Read More

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http://dx.doi.org/10.1002/ccr3.1615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099042PMC
August 2018
2 Reads

A Novel Frameshift Mutation (c.5387_5388insTT) in in Cornelia de Lange Syndrome with Severe Phenotype.

Ann Clin Lab Sci 2018 Jan;48(1):106-109

Department of Pediatrics, Kangdong Sacred Heart Hospital, Seoul, Korea

Cornelia de Lange syndrome (CdLS) is a developmental disorder which is characterized by typical facial features, upper extremity malformations, and growth and cognitive delays. The genes involved in CdLS encode the cohesin complex and its associated proteins; and mutations, which account for half of the cases, result in severe CdLS phenotypes. We describe a girl with CdLS, presenting with typical facial dysmorphism, cleft palate, hypertrichosis, upper limb hypertonicity, flexion contracture of elbows, micromelia, bilateral hearing loss, gastroesophageal reflux, and severe pyloric stenosis. Read More

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January 2018
5 Reads

Optimizing peripheral venous pressure waveforms in an awake pediatric patient by decreasing signal interference.

J Clin Monit Comput 2018 Dec 6;32(6):1149-1153. Epub 2018 Mar 6.

Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, USA.

The purpose of this technological notes paper is to describe our institution's experience collecting peripheral venous pressure (PVP) waveforms using a standard peripheral intravenous catheter in an awake pediatric patient. PVP waveforms were collected from patients with hypertrophic pyloric stenosis. PVP measurements were obtained prospectively at two time points during the hospitalization: admission to emergency department and after bolus in emergency department. Read More

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http://dx.doi.org/10.1007/s10877-018-0124-5DOI Listing
December 2018
13 Reads

A simulated training model for laparoscopic pyloromyotomy: Is 3D printing the way of the future?

J Pediatr Surg 2018 May 8;53(5):937-941. Epub 2018 Feb 8.

Division of Pediatric Surgery, Children's Hospital, London Health Sciences Centre, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. Electronic address:

Background: Hypertrophic pyloric stenosis (HPS) is a common neonatal condition treated with open or laparoscopic pyloromyotomy. 3D-printed organs offer realistic simulations to practice surgical techniques. The purpose of this study was to validate a 3D HPS stomach model and assess model reliability and surgical realism. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.02.016DOI Listing
May 2018
4 Reads

Protein Losing Enteropathy in Hennekam Syndrome.

Indian J Pediatr 2018 07 12;85(7):587-588. Epub 2018 Jan 12.

Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1007/s12098-017-2602-zDOI Listing
July 2018
8 Reads

An unusual surgical cause of pyloric stenosis in an 8-month-old infant.

Afr J Paediatr Surg 2017 Oct-Dec;14(4):79-82

Department of Paediatrics and Adolescent Health, Princess Marina Hospital, Gaborone, Botswana.

Infantile hypertrophic pyloric stenosis (IHPS) is the most common surgical cause of nonbilious, projectile vomiting in children. Its incidence is estimated to be 2-5/1000 live births and has been noted to be quite rare in African-Americans, Asians, and Indians. It is more common in infants under 6 months of age and is quite rare in older infants. Read More

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http://dx.doi.org/10.4103/ajps.AJPS_118_16DOI Listing
January 2019

William Ladd before the Halifax explosion.

Authors:
Don K Nakayama

J Pediatr Surg 2017 Dec 5;52(12):2093-2096. Epub 2017 Sep 5.

Department of Surgery, Florida International University, Sacred Heart Medical Group, Pensacola, FL. Electronic address:

Legend holds that treating the hundreds of children injured in the Halifax explosion of December 6, 1917, compelled Dr. William E. Ladd (1880-1967) to dedicate his career to the surgical care of infants and children. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00223468173054
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http://dx.doi.org/10.1016/j.jpedsurg.2017.08.047DOI Listing
December 2017
10 Reads

Application of color Doppler ultrasound combined with Doppler imaging artifacts in the diagnosis and estimate of congenital hypertrophic pyloric stenosis.

Sci Rep 2017 Aug 25;7(1):9527. Epub 2017 Aug 25.

Department of Medical Ultrasound, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.

Congenital Hypertrophic Pyloric Stenosis (CHPS) is a disease condition that is caused as a result of pylorus wall hypertrophy and hyperplasia. In this study, we used color Doppler flow imaging (CDFI) and Doppler artifacts technique to observe the blood flow of hypertrophic pylorus tissue and the dynamic imaging of liquid passing through the pyloric canal in CHPS infants. 65 cases of CHPS infants and 50 infants without CHPS served as control group. Read More

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http://dx.doi.org/10.1038/s41598-017-10264-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5573336PMC
August 2017
68 Reads

A breathtakingly rare presentation of pyloric stenosis.

Ir Med J 2017 Apr 10;110(4):555. Epub 2017 Apr 10.

Department of Paediatrics, Midland Regional Hospital, Mullingar, Ireland.

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April 2017
2 Reads

50 Years Ago in The Journal of Pediatrics: The Radiographic Diagnosis of Congenital Hypertrophic Pyloric Stenosis.

J Pediatr 2017 07;186:40

Tecnologico de Monterrey School of Medicine Monterrey, Nuevo León, Mexico.

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http://dx.doi.org/10.1016/j.jpeds.2017.01.038DOI Listing
July 2017
2 Reads

Does metabolic alkalosis influence cerebral oxygenation in infantile hypertrophic pyloric stenosis?

J Surg Res 2017 05 30;212:229-237. Epub 2017 Jan 30.

Department of Pediatric Surgery, St. Mary's Hospital, St. Elisabeth Group, Ruhr-University of Bochum, Herne, Germany.

Background: This pilot study focuses on regional tissue oxygenation (rSO) in patients with infantile hypertrophic pyloric stenosis in a perioperative setting. To investigate the influence of enhanced metabolic alkalosis (MA) on cerebral (c-rSO) and renal (r-rSO) tissue oxygenation, two-site near-infrared spectroscopy (NIRS) technology was applied.

Materials And Methods: Perioperative c-rSO, r-rSO, capillary blood gases, and electrolytes from 12 infants were retrospectively compared before and after correction of MA at admission (T1), before surgery (T2), and after surgery (T3). Read More

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http://dx.doi.org/10.1016/j.jss.2017.01.019DOI Listing
May 2017
44 Reads

Chronic Low Dose Prostaglandin and Neonatal Heart Block.

Pediatr Cardiol 2017 Oct 16;38(7):1515-1518. Epub 2017 May 16.

Department of Pediatrics, Division of Cardiology, Rush University Medical College, 1653 W. Congress Pkwy., Pavilion 654, Chicago, IL, 60612, USA.

Long-term prostaglandin use is commonly associated with side effects such as cortical proliferation of the bones, hypertrophic pyloric stenosis, and soft tissue swelling of the extremities. We report a neonate with critical coarctation of the aorta, who developed second and third degree atrioventricular blocks associated with prolonged prostaglandin E1 (PGE1) infusion. Interestingly, these conduction blocks only occurred at low PGE1 dose. Read More

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http://dx.doi.org/10.1007/s00246-017-1633-6DOI Listing
October 2017
30 Reads

Perinatal risk factors for infantile hypertrophic pyloric stenosis: A meta-analysis.

J Pediatr Surg 2017 Sep 15;52(9):1389-1397. Epub 2017 Mar 15.

Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China; Key Laboratory of Obstetric & Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, Sichuan University, Chengdu 610041, China; Department of Pediatrics, University of California, San Francisco, USA. Electronic address:

Background: Infantile hypertrophic pyloric stenosis (IHPS) is the most common surgical cause of nonbilious vomiting in infancy. The etiology of IHPS is not completely understood. Hence, we performed a meta-analysis to investigate the association between perinatal factors and IHPS onset. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2017.02.017DOI Listing
September 2017
5 Reads
1.311 Impact Factor

Excessive Bright Echoes Sign for Hypertrophic Pyloric Stenosis Suggest the Diagnosis: Gastric Pneumatosis and Portal Venous Gas in Infants Suggest HPS.

J Ultrasound Med 2017 May 10;36(5):1059-1063. Epub 2017 Mar 10.

University of Tennessee/Methodist Healthcare Radiology Residency Program, Memphis, Tennessee, USA.

We describe a new finding, the "excessive bright echoes" sign, for the diagnosis of hypertrophic pyloric stenosis (HPS). Portal venous gas and gastric wall pneumatosis were noted in 4 vomiting infants proven to have HPS. Portal venous gas can be concerning for ischemic bowel. Read More

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http://dx.doi.org/10.7863/ultra.16.04004DOI Listing
May 2017
6 Reads

Complications in common general pediatric surgery procedures.

Semin Pediatr Surg 2016 Dec 29;25(6):404-411. Epub 2016 Oct 29.

Department of Surgery, Phoenix Children's Hospital, 1919 E Thomas Rd, Phoenix, Arizona 85016. Electronic address:

Complications related to general pediatric surgery procedures are a major concern for pediatric surgeons and their patients. Although infrequent, when they occur the consequences can lead to significant morbidity and psychosocial stress. The purpose of this article is to discuss the common complications encountered during several common pediatric general surgery procedures including inguinal hernia repair (open and laparoscopic), umbilical hernia repair, laparoscopic pyloromyotomy, and laparoscopic appendectomy. Read More

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http://dx.doi.org/10.1053/j.sempedsurg.2016.10.002DOI Listing
December 2016
8 Reads

The timing and prevalence of intraoperative hypotension in infants undergoing laparoscopic pyloromyotomy at a tertiary pediatric hospital.

Paediatr Anaesth 2017 Jan 29;27(1):66-76. Epub 2016 Nov 29.

Department of Anesthesiology and Critical Care Medicine, Perelman School of Medicine at the University of Pennsylvania and The Children's Hospital of Philadelphia, Philadelphia, PA, USA.

Background: Intraoperative hypotension may be associated with adverse outcomes in children undergoing surgery. Infants and neonates under 6 months of age have less autoregulatory cerebral reserve than older infants, yet little information exists regarding when and how often intraoperative hypotension occurs in infants.

Aims: To better understand the epidemiology of intraoperative hypotension in infants, we aimed to determine the prevalence of intraoperative hypotension in a generally uniform population of infants undergoing laparoscopic pyloromyotomy. Read More

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http://dx.doi.org/10.1111/pan.13036DOI Listing
January 2017
14 Reads
1.742 Impact Factor

Update on endoscopic management of gastric outlet obstruction in children.

Authors:
Hsun-Chin Chao

World J Gastrointest Endosc 2016 Oct;8(18):635-645

Hsun-Chin Chao, Division of Gastroenterology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan 33305, Taiwan.

Endoscopic balloon dilatation (EBD) and surgical intervention are two most common and effective treatments for gastric outlet obstruction. Correction of gastric outlet obstruction without the need for surgery is an issue that has been tried to be resolved in these decades; this management has developed with EBD, advanced treatments like local steroid injection, electrocauterization, and stent have been added recently. The most common causes of pediatric gastric outlet obstruction are idiopathic hypertrophic pyloric stenosis, peptic ulcer disease followed by the ingestion of caustic substances, stenosis secondary to surgical anastomosis; antral web, duplication cyst, ectopic pancreas, and other rare conditions. Read More

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http://dx.doi.org/10.4253/wjge.v8.i18.635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5067470PMC
October 2016
2 Reads

Vomiting in infant with congenital nephrotic syndrome: Answers.

Pediatr Nephrol 2017 09 18;32(9):1521-1523. Epub 2016 Oct 18.

Department of Pediatrics, Hokkaido University Hospital, Kita 15-jo Nishi 7-Chome, Kita Ward, Sapporo City, Hokkaido, Japan.

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http://dx.doi.org/10.1007/s00467-016-3532-0DOI Listing
September 2017
4 Reads

Vomiting in an infant with congenital nephrotic syndrome: Questions.

Pediatr Nephrol 2017 Sep 18;32(9):1519-1520. Epub 2016 Oct 18.

Department of Pediatrics, Hokkaido University Hospital, Kita 15-jo Nishi 7-Chome, Kita Ward, Sapporo City, Hokkaido, Japan.

Background: Most patients with congenital nephrotic syndrome (CNS) exhibit a failure to thrive. A previous study reported that five of 41 (12 %) infants with CNS had hypertrophic pyloric stenosis (HPS) requiring surgery. The reason for this is undetermined, and there are few reports regarding the relationship between these conditions or their clinical course. Read More

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http://dx.doi.org/10.1007/s00467-016-3529-8DOI Listing
September 2017
8 Reads

Infantile hypertrophic pyloric stenosis with unusual presentations in Sagamu, Nigeria: a case report and review of the literature.

Pan Afr Med J 2016 2;24:114. Epub 2016 Jun 2.

Department of Paediatrics, Olabisi Onabanjo University Teaching Hospital, Sagamu, Nigeria.

A 24-day old female Nigerian neonate presented with protracted vomiting, fever and dehydration but without palpable abdominal tumour or visible gastric peristalsis. There was no derangement of serum electrolytes. The initial working diagnosis was Late-Onset Sepsis but abdominal ultrasonography showed features consistent with the diagnosis of IHPS. Read More

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http://dx.doi.org/10.11604/pamj.2016.24.114.8847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012754PMC
March 2017
21 Reads

Health disparities in infants with hypertrophic pyloric stenosis.

Am J Surg 2017 Aug 4;214(2):329-335. Epub 2016 Aug 4.

Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, USA.

Background: This study investigates whether health disparities exist in infants with hypertrophic pyloric stenosis (HPS), to identify factors affecting definitive treatment, and if more morbidity occurs.

Methods: A 6-year retrospective analysis was performed on infants with HPS. Analysis of variance was used to evaluate the impact of socioeconomic factors on disease severity and hospitalization. Read More

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http://dx.doi.org/10.1016/j.amjsurg.2016.07.009DOI Listing
August 2017
4 Reads

Preface.

Semin Pediatr Surg 2016 Aug 24;25(4):197. Epub 2016 May 24.

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http://dx.doi.org/10.1053/j.sempedsurg.2016.05.008DOI Listing
August 2016
4 Reads

The cervix sign and other sonographic signs of hypertrophic pyloric stenosis.

Abdom Radiol (NY) 2016 Oct;41(10):2085-6

Department of Paediatrics, SRM University, Kattankulathur Campus, Chennai, Tamilnadu, India.

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http://dx.doi.org/10.1007/s00261-016-0809-5DOI Listing
October 2016
3 Reads

Laparoscopic pyloromyotomy decreases postoperative length of stay in children with hypertrophic pyloric stenosis.

J Pediatr Surg 2016 Sep 31;51(9):1436-9. Epub 2016 May 31.

Department of Pediatric Surgery, Nationwide Children's Hospital, Columbus, OH. Electronic address:

Objective: To determine the impact of laparoscopic versus open pyloromyotomy on postoperative length of stay (LOS).

Materials And Methods: The 2013 National Surgical Quality Improvement Project Pediatric database was queried for all cases of pyloromyotomy performed on children <1year old with congenital hypertrophic pyloric stenosis. Demographics, clinical, and perioperative characteristics for patients with and without a prolonged postoperative LOS, defined as >1day, were compared. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2016.05.006DOI Listing
September 2016
18 Reads

Adverse Events and Resource Utilization After Spinal and General Anesthesia in Infants Undergoing Pyloromyotomy.

Reg Anesth Pain Med 2016 Jul-Aug;41(4):532-7

From the Departments of *Anesthesiology and †Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY; ‡Department of Anesthesiology, University of Vermont Medical Center, Burlington, VT; §Mailman School of Public Health, Columbia University; and ∥Department of Epidemiology, Columbia University College of Physicians and Surgeons, New York, NY; and ¶Department of Pediatrics, University of Vermont Medical Center, Burlington, VT.

Background And Objectives: Interest in spinal anesthesia (SA) is increasing because of concern about the long-term effects of intravenous (IV) and inhaled anesthetics in young children. This study compared SA versus general anesthesia (GA) in infants undergoing pyloromyotomy.

Methods: Between 2000 to 2013, the University of Vermont Medical Center almost exclusively used SA for infant pyloromyotomy surgery, whereas Columbia University Medical Center relied on GA. Read More

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http://dx.doi.org/10.1097/AAP.0000000000000421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4912426PMC
March 2017
13 Reads
3.090 Impact Factor

Efficacy of Medical Treatment for Infantile Hypertrophic Pyloric Stenosis: A Meta-analysis.

Pediatr Neonatol 2016 12 8;57(6):515-521. Epub 2016 Apr 8.

Department of Pediatrics, China Medical University Children's Hospital, Taichung, Taiwan; School of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:

Background: Infantile hypertrophic pyloric stenosis (IHPS) is a common disease in infancy. Pyloromyotomy is universally considered the treatment for IHPS; however, oral or intravenous atropine has been reappraised for the treatment of IHPS in the past 20 years. We investigated the efficacy of atropine in the medical management of IHPS by using meta-analysis and investigated the sonographic changes of the pyloric canal, as well as the efficacy and adverse effects of atropine. Read More

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http://dx.doi.org/10.1016/j.pedneo.2016.02.005DOI Listing
December 2016
28 Reads
1 Citation
0.880 Impact Factor

Pediatric Abdominal Pain: An Emergency Medicine Perspective.

Emerg Med Clin North Am 2016 May;34(2):341-61

Emergency Medicine Residency Program, Department of Emergency Medicine, Carolinas Medical Center, 1000 Blythe Boulevard, MEB Floor 3, Charlotte, NC 28203, USA.

Abdominal pain is a common complaint that leads to pediatric patients seeking emergency care. The emergency care provider has the arduous task of determining which child likely has a benign cause and not missing the devastating condition that needs emergent attention. This article reviews common benign causes of abdominal pain as well as some of the cannot-miss emergent causes. Read More

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http://dx.doi.org/10.1016/j.emc.2015.12.010DOI Listing
May 2016
1 Read

Acetaminophen for analgesia following pyloromyotomy: does the route of administration make a difference?

J Pain Res 2016 8;9:123-7. Epub 2016 Mar 8.

Department of Anesthesiology and Pain Medicine, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH, USA; Department of Anesthesiology and Pain Medicine, The Ohio State University College of Medicine, Columbus, OH, USA; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA.

Background: During the perioperative care of infants with hypertrophic pyloric stenosis, an opioid-sparing technique is often advocated due to concerns such as postoperative hypoventilation and apnea. Although the rectal administration of acetaminophen is commonly employed, an intravenous (IV) preparation is also currently available, but only limited data are available regarding IV acetaminophen use for infants undergoing pyloromyotomy. The objective of the current study was to compare the efficacy of IV and rectal acetaminophen for postoperative analgesia in infants undergoing laparoscopic pyloromyotomy. Read More

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http://dx.doi.org/10.2147/JPR.S100607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790489PMC
March 2016
1 Read

Trends in Pediatric Surgery Operative Volume among Residents and Fellows: Improving the Experience for All.

J Am Coll Surg 2016 06 20;222(6):1082-8. Epub 2015 Dec 20.

Department of Surgery, Boston Medical Center, Boston University School of Medicine, Boston, MA. Electronic address:

Background: The ACGME requires general surgery residents (GSR) to perform 20 pediatric surgery cases as part of the total 750 cases before graduation.

Study Design: We queried the ACGME General Surgery (1999 to 2014) and Pediatric Surgery (2003 to 2014) Case Logs for all pediatric operations performed during training. Means (±SD) and medians (10(th):90(th) percentiles) were compared, and R(2) was calculated for all trends. Read More

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http://dx.doi.org/10.1016/j.jamcollsurg.2015.11.034DOI Listing
June 2016
7 Reads

Feeding Post-Pyloromyotomy: A Meta-analysis.

Pediatrics 2016 Jan 30;137(1). Epub 2015 Dec 30.

Department of Pediatric Surgery, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada; and Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada

Context: Postoperative emesis is common after pyloromyotomy. Although postoperative feeding is likely to be an influencing factor, there is no consensus on optimal feeding.

Objective: To compare the effect of feeding regimens on clinical outcomes of infants after pyloromyotomy. Read More

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http://dx.doi.org/10.1542/peds.2015-2550DOI Listing
January 2016
34 Reads

No association between macrolide treatment in infancy and later pyloric stenosis in Sweden.

Eur J Epidemiol 2016 Mar 22;31(3):331-2. Epub 2015 Dec 22.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s10654-015-0114-6DOI Listing
March 2016
2 Reads

Infantile hypertrophic pyloric stenosis at a tertiary care hospital in Tanzania: a surgical experience with 102 patients over a 5-year period.

BMC Res Notes 2015 Nov 18;8:690. Epub 2015 Nov 18.

Department of Surgery, Bugando Medical Centre, Mwanza, Tanzania.

Background: Infantile hypertrophic pyloric stenosis (IHPS) is the most common cause of gastric outlet obstruction in infants. There is paucity of published data regarding this condition in our setting. This study describes the clinical presentation, mode of treatment and outcome of treatment of this disease and identifies factors responsible for poor outcome of these patients. Read More

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http://dx.doi.org/10.1186/s13104-015-1660-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652415PMC
November 2015
2 Reads

Perioperative care of infants with pyloric stenosis.

Paediatr Anaesth 2015 Dec 22;25(12):1193-206. Epub 2015 Oct 22.

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.

Pyloric stenosis (PS) is one of the most common surgical conditions affecting neonates and young infants. The definitive treatment for PS is surgical pyloromyotomy, either open or laparoscopic. However, surgical intervention should never be considered urgent or emergent. Read More

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http://dx.doi.org/10.1111/pan.12792DOI Listing
December 2015
1 Read

Recurrent duplications of 17q12 associated with variable phenotypes.

Am J Med Genet A 2015 Dec 30;167A(12):3038-45. Epub 2015 Sep 30.

Division of Genetic Medicine, Department of Pediatrics, University of Washington and Seattle Children's Hospital, Seattle, Washington.

The ability to identify the clinical nature of the recurrent duplication of chromosome 17q12 has been limited by its rarity and the diverse range of phenotypes associated with this genomic change. In order to further define the clinical features of affected patients, detailed clinical information was collected in the largest series to date (30 patients and 2 of their siblings) through a multi-institutional collaborative effort. The majority of patients presented with developmental delays varying from mild to severe. Read More

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http://dx.doi.org/10.1002/ajmg.a.37351DOI Listing
December 2015
55 Reads

Sudden-Onset Bilateral Blindness in a Young Girl Receiving Parenteral Nutrition: Case Report and Review of Literature.

JPEN J Parenter Enteral Nutr 2017 09 19;41(7):1240-1244. Epub 2015 Aug 19.

3 Department of Pediatrics, University College of Medical Sciences and Guru Tegh Bahadur Hospital, Delhi, India.

Background: Parenteral nutrition (PN) via a central venous catheter is routinely used for surgical patients without a functioning gastrointestinal tract. Complications of PN can be metabolic and thrombotic. Blindness is a rare and unexpected complication. Read More

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http://dx.doi.org/10.1177/0148607115601997DOI Listing
September 2017
9 Reads
3.151 Impact Factor

Endoscopic Treatment of Gastric Outlet Obstruction Secondary to Accidental Acid Ingestion in a Child.

J Pediatr Gastroenterol Nutr 2016 Jan;62(1):90-2

Department of Pediatrics, School of Medicine of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.

Accidental corrosive ingestion is not rare in pediatric patients in developing countries. We report a case of gastric outlet obstruction after the accidental ingestion of an acidic substance by a child who was successfully treated with endoscopic balloon dilatation. Read More

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http://dx.doi.org/10.1097/MPG.0000000000000936DOI Listing
January 2016
3 Reads

Mosaic partial deletion of PTPN12 in a child with interrupted aortic arch type A.

Am J Med Genet A 2015 Nov 6;167A(11):2674-83. Epub 2015 Aug 6.

Division of Genetics and Metabolism, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota.

Congenital heart malformations, including those of the great vessels, are among the most common human birth defects. The goal of this study was to identify the significance of a de novo mosaic PTPN12 partial deletion identified in a newborn with an interrupted aortic arch type A, ventricular septal defect, and pyloric stenosis. PTPN12, a downstream target of the RAS pathway, has a known role in endothelial cell adhesion and migration. Read More

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http://dx.doi.org/10.1002/ajmg.a.37279DOI Listing
November 2015
8 Reads

Ultrasound-guided paravertebral block for pyloromyotomy in 3 neonates with congenital hypertrophic pyloric stenosis.

Braz J Anesthesiol 2015 Jul-Aug;65(4):302-5. Epub 2015 Apr 28.

Departamento de Anestesiología y Reanimación, Hospital Universitario Virgen del Rocío, Sevilla, Spain.

Background And Objectives: Hypertrophic pyloric stenosis is a relatively common affection of gastrointestinal tract in childhood that results in symptoms, such as projectile vomiting and metabolic disorders that imply a high risk of aspiration during anesthetic induction. In this way, the carrying out of a technique with general anesthesia and intravenous rapid sequence induction, preoxygenation and cricoid pressure are recommended. After the correction of systemic metabolic alkalosis and pH normalization, cerebrospinal fluid can keep a state of metabolic alkalosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01040014140019
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http://dx.doi.org/10.1016/j.bjane.2014.03.012DOI Listing
December 2016
4 Reads

Spontaneous Intestinal Perforation and Infantile Hypertrophic Pyloric Stenosis in a Preterm Neonate: A Linked Etiopathogenesis?

Indian J Pediatr 2016 Feb 10;83(2):178. Epub 2015 Jun 10.

Department of Pediatrics and Neonatology, Cloudnine Hospital, Old Airport Road, Kodihalli, Murugeshpalya, Bangalore, 560017, India.

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http://dx.doi.org/10.1007/s12098-015-1807-2DOI Listing
February 2016
1 Read

[Ultrasound-guided paravertebral block for pyloromyotomy in 3 neonates with congenital hypertrophic pyloric stenosis].

Rev Bras Anestesiol 2015 Jul-Aug;65(4):302-5. Epub 2015 May 7.

Departamento de Anestesiologia e Reanimação, Hospital Universitário Virgen del Rocío, Sevilha, Espanha.

Background And Objectives: Hypertrophic pyloric stenosis is a relatively common affection of gastrointestinal tract in childhood that results in symptoms, such as projectile vomiting and metabolic disorders that imply a high risk of aspiration during anesthetic induction. In this way, the carrying out of a technique with general anesthesia and intravenous rapid sequence induction, preoxygenation and cricoid pressure are recommended. After the correction of systemic metabolic alkalosis and pH normalization, cerebrospinal fluid can keep a state of metabolic alkalosis. Read More

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http://dx.doi.org/10.1016/j.bjan.2014.03.011DOI Listing
June 2015
3 Reads