2,664 results match your criteria Pediatrics Otitis Media


Forecast modeling to identify changes in pediatric emergency department utilization during the COVID-19 pandemic.

Am J Emerg Med 2021 May 21;49:142-147. Epub 2021 May 21.

Division of Pediatric Critical Care Medicine, Department of Critical Care Medicine, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, United States of America; Division of Health Informatics, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, United States of America.

Objective: To identify trends in pediatric emergency department (ED) utilization following the COVID-19 pandemic.

Methods: We performed a cross-sectional study from 37 geographically diverse US children's hospitals. We included ED encounters between January 1, 2010 and December 31, 2020, transformed into time-series data. Read More

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Frequency of hearing impairment in children between the ages of 2 and 10 years with middle ear infection.

J Pak Med Assoc 2021 Jun;71(6):1662-1665

Riphah International University, Lahore, Pakistan.

This study was conducted on children between 2 and 10 years age to determine the frequency of hearing impairment in middle ear infection. It was a cross-sectional survey, done at Riphah International University from August 2018 to January 2019. Data was collected from the ENT Department of Children's Hospital Lahore through convenience sampling technique and included 52 patients with middle ear infection. Read More

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Primary ciliary dyskinesia due to CCNO mutations-A genotype-phenotype correlation contribution.

Pediatr Pulmonol 2021 Jun 8. Epub 2021 Jun 8.

Paediatric Respiratory Unit, Department of Paediatrics, Hospital de Santa Maria-Centro Hospitalar Universitário de Lisboa Norte, Lisbon, Portugal.

Primary ciliary dyskinesia (PCD) is genetically and clinically heterogeneous. CCNO mutations are associated with chronic destructive lung disease and were first described in 2014. Early reports suggest that CCNO is mutated more frequently than expected, however, these are considered rare. Read More

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Heiner Syndrome and Milk Hypersensitivity: An Updated Overview on the Current Evidence.

Nutrients 2021 May 18;13(5). Epub 2021 May 18.

Department of Health Science, University of Florence, 70126 Florence, Italy.

Infants affected by Heiner syndrome (HS) display chronic upper or lower respiratory tract infections, including otitis media or pneumonia. Clinically, gastrointestinal signs and symptoms, anemia, recurrent fever and failure to thrive can be also present. Chest X-rays can show patchy infiltrates miming pneumonia. Read More

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A Case of Primary Ciliary Dyskinesia Caused by a Mutation in , Which Was Diagnosed Owing to Infection.

Pediatr Rep 2021 May 10;13(2):241-244. Epub 2021 May 10.

Department of Pediatrics and Adolescent Medicine, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

We report a Japanese 5-year-old boy with primary ciliary dyskinesia (PCD) which was diagnosed owing to (CD) infection caused by prolonged antibiotic exposure. He had intractable otitis media with effusion (OME) and had abdominal pain and diarrhea for 4 months after starting antibiotics administration. His stool contained CD toxin. Read More

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School Nurses on the Front Lines of Healthcare: Getting aHEAD of EmergENT Eye, Ear, Nose, and Throat Infections.

NASN Sch Nurse 2021 Jun 1:1942602X211019109. Epub 2021 Jun 1.

Professor, Departments of Emergency Medicine and Pediatrics, Penn State College of Medicine, Attending Pediatric Emergency Medicine physician, Penn State Hershey Medical Center, Hershey, PA.

School nurses may deal with various common infectious eye, ear, nose, and throat-related chief complaints in regular practice. Recognizing the signs and symptoms of severe infection is paramount to preventing life-threatening complications that can have both acute and long-term implications. Distinguishing urgent and emergent eye, ear, nose, and throat conditions to send to the emergency department is integral to reducing the morbidity associated with these conditions. Read More

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Tissue microbiota in nasopharyngeal adenoid and its association with pneumococcal carriage.

Microb Pathog 2021 May 24;157:104999. Epub 2021 May 24.

Molecular Infectious Disease Research Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan. Electronic address:

The microbial colonization in the nasopharynx is a prerequisite for the onset of infectious diseases. For successful infection, pathogens should overcome host defenses as well as compete effectively with the resident microbiota. Hence, elucidating the richness and diversity of the microbiome at the site of pathogen colonization is pivotal. Read More

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The role of as a pathogen in children: a multicentre retrospective study.

J Med Microbiol 2021 May;70(5)

Department of Paediatric Emergency Medicine, Hadassah-Hebrew University Medical Centre, Jerusalem, Israel.

(SL), a tube coagulase negative , is known to be pathogenic in adults, causing mainly skin infections. Previous studies assessing SL's role in paediatric populations are sparse and are mainly limited to case reports. Present the clinical characteristics consistent with SL infections and its putative role as a pathogen in the paediatric population. Read More

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Efficient and accurate identification of ear diseases using an ensemble deep learning model.

Sci Rep 2021 May 25;11(1):10839. Epub 2021 May 25.

College of Mathematics and Systems Science, Guangdong Polytechnic Normal University, Guangzhou, 510665, China.

Early detection and appropriate medical treatment are of great use for ear disease. However, a new diagnostic strategy is necessary for the absence of experts and relatively low diagnostic accuracy, in which deep learning plays an important role. This paper puts forward a mechanic learning model which uses abundant otoscope image data gained in clinical cases to achieve an automatic diagnosis of ear diseases in real time. Read More

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PCV10 elicits Protein D IgG responses in Papua New Guinean children but has no impact on NTHi carriage in the first two years of life.

Vaccine 2021 Jun 21;39(26):3486-3492. Epub 2021 May 21.

Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Western Australia, Australia; Centre for Child Health Research, University of Western Australia, Perth, Australia. Electronic address:

Background: Nasopharyngeal colonisation with nontypeable Haemophilus influenzae (NTHi) is associated with development of infections including pneumonia and otitis media. The 10-valent pneumococcal conjugate vaccine (PCV10) uses NTHi Protein D (PD) as a carrier. Papua New Guinean children have exceptionally early and dense NTHi carriage, and high rates of NTHi-associated disease. Read More

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Cerebral haemorrhagic infarction associated with acute otitis media in a 4-year-old boy.

BMJ Case Rep 2021 May 21;14(5). Epub 2021 May 21.

Department of Pediatrics, Dokkyo Medical University, Shimotsuga, Tochigi, Japan.

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Nontypeable Otitis Media: Mastoiditis and Meningitis Complicated with Central Venous Thrombosis in an Immunocompetent Child.

Case Rep Infect Dis 2021 13;2021:8845200. Epub 2021 Mar 13.

Ataşehir Memorial Hospital, Clinic of Pediatrics, Istanbul, Turkey.

Implementation of the type B (Hib) conjugate vaccine brought about a reduction in the number of cases and morbidity from type B but an increase in nontypeable strain infections. Nontypeable (NTHi) commonly colonizes children's upper respiratory tract and causes otitis media, sinusitis, and bronchitis. Invasive NTHi diseases, such as meningitis and septicemia, have rarely been reported. Read More

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Sigmoid Sinus Thrombosis as a Complication of Acute Otitis Media in a 6-Year-Old Male.

Ear Nose Throat J 2021 May 16:1455613211015752. Epub 2021 May 16.

Department of Otorhinolaryngology-Head and Neck Surgery, "G. Papanikolaou" General Hospital, Thessaloniki, Greece.

Sigmoid sinus thrombosis (SST) is a potentially life-threatening complication of otitis media which is nowadays rare due to the widespread use of antibiotics. A high index of suspicion is necessary to allow for a timely diagnostic and therapeutic intervention. Intravenous wide-spectrum antibiotics and a cortical mastoidectomy are the mainstay of treatment. Read More

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Improving Delayed Antibiotic Prescribing for Acute Otitis Media.

Pediatrics 2021 Jun 12;147(6). Epub 2021 May 12.

Colorado Department of Public Health and Environment, Denver, Colorado.

Objectives: Acute otitis media (AOM) is the most-common indication for antibiotics in children. Delayed antibiotic prescribing for AOM can significantly reduce unnecessary antibiotic use and is recommended by the American Academy of Pediatrics for select children. We sought to improve delayed prescribing for AOM across 8 outpatient pediatric practices in Colorado. Read More

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Management of Recurrent Acute Otitis Media.

Authors:
Ellen R Wald

N Engl J Med 2021 05;384(19):1859-1860

From the Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison.

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Tympanostomy Tubes or Medical Management for Recurrent Acute Otitis Media.

N Engl J Med 2021 05;384(19):1789-1799

From the Departments of Pediatrics (A.H., J.L.P., M.H., D.H.K., S.B., G.B.M.P., T.R.S., J.M.M., M.K.-L., H.L., K.Y., J.P.N., N.S.) and Otolaryngology (D.H.C., J.E.D.), University of Pittsburgh School of Medicine, UPMC Children's Hospital of Pittsburgh, the Department of Biostatistics, University of Pittsburgh Graduate School of Public Health (J.-H.J.), and Children's Community Pediatrics (N.L.C., B.C.) - all in Pittsburgh; Children's National Medical Center, Washington, DC (D.P., D.E.F.); and Kentucky Pediatric and Adult Research, Bardstown (S.L.B.).

Background: Official recommendations differ regarding tympanostomy-tube placement for children with recurrent acute otitis media.

Methods: We randomly assigned children 6 to 35 months of age who had had at least three episodes of acute otitis media within 6 months, or at least four episodes within 12 months with at least one episode within the preceding 6 months, to either undergo tympanostomy-tube placement or receive medical management involving episodic antimicrobial treatment. The primary outcome was the mean number of episodes of acute otitis media per child-year (rate) during a 2-year period. Read More

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Cystic fibrosis mutation classes in pediatric otitis media - Fickle or faulty?

Am J Otolaryngol 2021 Apr 20;42(6):103067. Epub 2021 Apr 20.

Department of Otolaryngology, University of Pittsburgh School of Medicine, 203 Lothrop St. Suite 500, Pittsburgh, PA 15213, USA; Division of Pediatric Otolaryngology, UPMC Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA 15224, USA; Department of Communication Science and Disorders, University of Pittsburgh School of Health & Rehabilitation, Forbes Tower, 3600 Forbes Ave., Pittsburgh, PA 15260, USA. Electronic address:

Purpose: Recent data have challenged the historical paradigm that cystic fibrosis (CF) protects against otitis media (OM). These findings raised questions about the pathogenesis of this ostensible change. In this study our aim is to characterize acute OM (AOM) risk based on CF genotype. Read More

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Evaluation of digital otoscopy in pediatric patients: A prospective randomized controlled clinical trial.

Am J Emerg Med 2021 Apr 27;46:150-155. Epub 2021 Apr 27.

Division of Pediatric Emergency Medicine, Department of Pediatrics, Johns Hopkins University, United States of America.

Background: Acute otitis media is often misdiagnosed. Pediatric trainees learn otoscopy from supervisors who cannot concurrently view the eardrum. Digital, smartphone otoscopes show promise to improve the visibility and learning due to a concurrent view by trainees and supervisors. Read More

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Otitis Media and Obesity-An Unusual Relationship in Children.

Healthcare (Basel) 2021 Apr 14;9(4). Epub 2021 Apr 14.

Pediatrics Department, Grigore T. Popa University of Medicine and Pharmacy, 16 Universitatii Street, 700115 Iasi, Romania.

Otitis media (OM) represents a public health matter, being the main cause of preventable hearing loss in pediatric patients. Besides well-established risk factors for developing OM, such as craniofacial abnormalities, prematurity, low birth weight, or tobacco exposure, there is evidence that obesity could be associated with a high incidence of OM. Our aim is to perform a literature review on the state of current published research on the relationship between OM and obesity and to discuss the interconnectivity between these two entities. Read More

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Sepsis in a Previously Healthy Infant with Subcutaneous Nodules and Mastoid Bone Destruction.

J Pediatr Intensive Care 2021 Jun 8;10(2):148-151. Epub 2020 May 8.

Division of Pediatric Immunology Diseases, Dr. Sami Ulus Maternity and Children's Training and Research Hospital, Ankara, Turkey.

septicemia is rare in previously healthy children. Skin lesions such as subcutaneous nodules and ecthyma gangrenosum may be the first manifestation of infection that have rarely been reported. Herein we reported a previously healthy 6-month-old boy patient who presented with suppurative otitis media, multiple nodules, septic shock, and was identified in cultures of the blood, skin lesions, and purulent material of his ears. Read More

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Effects of nasopharyngeal microbiota in respiratory infections and allergies.

Clin Exp Pediatr 2021 Apr 15. Epub 2021 Apr 15.

Division of Pediatric Infectious Diseases, Departments of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea.

The human microbiome, which consists of a collective cluster of commensal, symbiotic, and pathogenic microorganisms living in the human body, plays a key role in host health and immunity. The human nasal cavity harbors commensal bacteria that suppress the colonization of opportunistic pathogens. However, dysbiosis of the nasal microbial community is associated with many diseases, such as acute respiratory infections including otitis media, sinusitis and bronchitis and allergic respiratory diseases including asthma. Read More

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The Development, Implementation and Evaluation of an Acute Otitis Media Education Website.

Acad Pediatr 2021 Apr 7. Epub 2021 Apr 7.

Professor Emeritus, General Academic Pediatrics, University of Texas Medical Branch at Galveston, Galveston, TX.

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Decreased miRNA-320e correlates with allergy in children with otitis media with effusion.

Auris Nasus Larynx 2021 Apr 1. Epub 2021 Apr 1.

Department of Pediatric Otolaryngology, Poznan University of Medical Sciences, Szpitalna 27/33 60-572 Poznań, Poland.

Objective: Otitis media with effusion (OME) is a common childhood disease and the main cause of conductive hearing loss in this age group. Many factors predispose to OME but allergy is still widely disputed. The answer may lay in the molecular mechanisms of ear exudate formation and the recent studies showed miRNAs might take part in it. Read More

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A pediatric case of primary ciliary dyskinesia caused by novel copy number variation in PIH1D3.

Auris Nasus Larynx 2021 Mar 31. Epub 2021 Mar 31.

Department of Otorhinolaryngology, Head & Neck Surgery, Mie University Graduate School of Medicine, Tsu, Japan. Electronic address:

An 11-month-old boy with productive cough was referred to our hospital. He had nasal obstruction immediately after birth, and wheezing, wet cough, and rhinorrhea were observed daily after the neonatal period. Clinical and imaging findings revealed secretory otitis media, chronic sinusitis, and bronchiectasis. Read More

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Immunoglobulins and Transcription Factors in Otitis Media.

Int J Mol Sci 2021 Mar 21;22(6). Epub 2021 Mar 21.

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Kyung Hee University, Seoul 02447, Korea.

The causes of otitis media (OM) involve bacterial and viral infection, anatomo-physiological abnormalities of the Eustachian canal and nasopharynx, allergic rhinitis, group childcare centers, second-hand smoking, obesity, immaturity and defects of the immune system, formula feeding, sex, race, and age. OM is accompanied by complex and diverse interactions among bacteria, viruses, inflammatory cells, immune cells, and epithelial cells. The present study summarizes the antibodies that contribute to immune reactions in all types of otitis media, including acute otitis media, otitis media with effusion, and chronic otitis media with or without cholesteatoma, as well as the transcription factors that induce the production of these antibodies. Read More

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Risk Factors for Postoperative Bleeding after Adenoidectomy.

Children (Basel) 2021 Mar 21;8(3). Epub 2021 Mar 21.

Department of Pediatrics, University Hospital Brno and Faculty of Medicine, Masaryk University, Černopolní 9, 61300 Brno, Czech Republic.

Importance: Postoperative bleeding is a common and potentially life-threatening complication. Precise identification of risk factors in addition to the basic ones, such as coagulation parameters, is certainly very desirable.

Objective: The aim of this study was to identify other possible risk factors for bleeding after adenoidectomy in children. Read More

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Successful living donor liver transplantation for liver failure due to maternal T cell engraftment following cord blood transplantation in X-linked severe combined immunodeficiency disease: Case report.

Am J Transplant 2021 Apr 1. Epub 2021 Apr 1.

Department of Gastroenterological, General and Transplant Surgery, Jichi Medical University, Tochigi-ken, Japan.

Maternal T cells from perinatal transplacental passage have been identified in up to 40% of patients with severe combined immunodeficiency (SCID). Although engrafted maternal T cells sometimes injure newborn tissue, liver failure due to maternal T cells has not been reported. We rescued a boy with X-linked SCID who developed liver failure due to engrafted maternal T cell invasion following living donor liver transplantation (LDLT) following unrelated umbilical cord blood transplantation (UCBT). Read More

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Primary bilateral tuberculous otitis media with peripheral facial paralysis: a case report and literature review.

Int J Clin Exp Pathol 2021 1;14(3):304-313. Epub 2021 Mar 1.

Department of Otolaryngology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine Hangzhou 310006, Zhejiang, China.

Tuberculous otitis media (TOM) is a rare disease. This study presents our experience in the diagnosis and treatment of TOM. A 49-year-old female had repeated ear discharge, vertigo, and severe hearing loss for six years, and underwent mastoid surgery four times because she was misdiagnosed with chronic suppurative otitis media. Read More

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Nasopharyngeal carriage of otitis media pathogens in infants receiving 10-valent non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV10), 13-valent pneumococcal conjugate vaccine (PCV13) or a mixed primary schedule of both vaccines: A randomised controlled trial.

Vaccine 2021 04 23;39(16):2264-2273. Epub 2021 Mar 23.

Child Health Division, Menzies School of Heath Research, Charles Darwin University, PO Box 41096, Casuarina, Northern Territory, Australia. Electronic address:

Background: Aboriginal children in Northern Australia have a high burden of otitis media, driven by early and persistent nasopharyngeal carriage of otopathogens, including non-typeable Haemophilus influenzae (NTHi) and Streptococcus pneumoniae (Spn). In this context, does a combined mixed primary series of Synflorix and Prevenar13 provide better protection against nasopharyngeal carriage of NTHi and Spn serotypes 3, 6A and 19A than either vaccine alone?

Methods: Aboriginal infants (n = 425) were randomised to receive Synflorix™ (S, PHiD-CV10) or Prevenar13™ (P, PCV13) at 2, 4 and 6 months (_SSS or _PPP, respectively), or a 4-dose early mixed primary series of PHiD-CV10 at 1, 2 and 4 months and PCV13 at 6 months of age (SSSP). Nasopharyngeal swabs were collected at 1, 2, 4, 6 and 7 months of age. Read More

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Facial nerve palsy with acute otitis media associated with EB virus infection.

Pediatr Int 2021 May 25;63(5):599-600. Epub 2021 Mar 25.

Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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