1,032 results match your criteria Pediatrics Mumps


Beware of α-lactalbumin as a hidden allergen in measles, mumps, and rubella vaccine in the patients with cow's milk allergy.

Pediatr Allergy Immunol 2022 06;33(6)

Division of Pediatrics, Department of Pediatric Allergy and Immunology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey.

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EULAR/PRES recommendations for vaccination of paediatric patients with autoimmune inflammatory rheumatic diseases: update 2021.

Ann Rheum Dis 2022 Jun 20. Epub 2022 Jun 20.

RITA, European Reference Networks, Brussels, Belgium.

Objectives: Recent insights supporting the safety of live-attenuated vaccines and novel studies on the immunogenicity of vaccinations in the era of biological disease-modifying antirheumatic drugs in paediatric patients with autoimmune/inflammatory rheumatic diseases (pedAIIRD) necessitated updating the EULAR recommendations.

Methods: Recommendations were developed using the EULAR standard operating procedures. Two international expert committees were formed to update the vaccination recommendations for both paediatric and adult patients with AIIRD. Read More

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Immunogenicity after outbreak response immunization activities among young healthcare workers with secondary vaccine failure during the measles epidemic in Korea, 2019.

BMC Infect Dis 2022 Jun 8;22(1):530. Epub 2022 Jun 8.

Division of Infectious Diseases, Department of Medicine, Korea University Ansan Hospital, Korea University College of Medicine, 123 Jeokgeum-ro, Danwon-gu, 15355, Ansan, Republic of Korea.

Background: Despite high vaccination coverage, measles outbreaks have been reported in measles elimination countries, especially among healthcare workers in their 20 and 30 s. This study was designed to identify measles-susceptible individuals and to evaluate whether primary or secondary vaccine failure occurred during measles outbreak response immunization (ORI) activities.

Methods: The study population was divided into three groups as follows: natural immunity group (Group 1), vaccine-induced immunity group (Group 2), and vaccine failure group (Group 3). Read More

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Immunisation status of UK-bound refugees between January, 2018, and October, 2019: a retrospective, population-based cross-sectional study.

Lancet Public Health 2022 May 27. Epub 2022 May 27.

Migrant Health Research Group, Institute for Infection and Immunity, St George's, University of London, London, UK. Electronic address:

Background: WHO's new Immunization Agenda 2030 places a focus on ensuring migrants and other marginalised groups are offered catch-up vaccinations across the life-course. Yet, it is not known to what extent specific groups, such as refugees, are immunised according to host country schedules, and the implications for policy and practice. We aimed to assess the immunisation coverage of UK-bound refugees undergoing International Organization for Migration (IOM) health assessments through UK resettlement schemes, and calculate risk factors for under-immunisation. Read More

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The measles, mumps, rubella, varicella vaccination was safe in children with acute egg food protein-induced enterocolitis syndrome but anxiety was high.

Acta Paediatr 2022 May 17. Epub 2022 May 17.

Department of Life Sciences and Public Health, Pediatric Allergy Unit, Pediatrics Section, Policlinico Gemelli Universitary Foundation IRCCS, Catholic University of Sacre Hearth, Rome, Italy.

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Influence of measles-mumps-rubella vaccine series initiation and completion on influenza vaccination among adolescents.

Int J Pediatr Adolesc Med 2022 Mar 4;9(1):11-15. Epub 2020 Dec 4.

Department of Pediatrics, Brody School of Medicine, East Carolina University, Greenville, NC, USA.

Background: Influenza vaccine participation in adolescents is low. Barriers to the influenza vaccine may be shared with the measles-mumps-rubella (MMR) vaccine.

Methods: We studied adolescents aged 13-17 years who participated in the National Immunization Survey-Teen between 2011 and 2017 (N = 129,200). Read More

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Poor Uptake of MMR Vaccine 1-year Post-Measles Outbreak: New York City and Israel.

J Pediatric Infect Dis Soc 2022 Apr 27. Epub 2022 Apr 27.

Department of Pediatrics, Division of Pediatric Infectious Diseases, New York University Grossman School of Medicine, New York, New York, USA.

Background: In 2018-2019, large outbreaks of measles occurred in Israel and in New York City, driven in part by travel of unimmunized children between the 2 communities.

Methods: A retrospective chart review was conducted for children tested for measles (March 2018-September 2019) at NYU Langone Health in New York, NY, and in Ramla subdistrict, Israel. Vaccination records were reviewed to determine vaccination status for measles, mumps, and rubella (MMR) at the time of measles testing and 1-year post-testing. Read More

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Presternal swelling: remember mumps.

Arch Dis Child 2022 Apr 25. Epub 2022 Apr 25.

Department of Child and Adolescent Health, Mater Dei Hospital, Msida, Malta.

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Titerphilia - The Irresistible Urge to Measure Postimmunization Antibody Values.

Pediatr Infect Dis J 2022 06 6;41(6):490-491. Epub 2022 May 6.

Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Some physicians and parents request to measure antimeasles serum IgG antibodies after measles-mumps-rubella (MMR) vaccination. Often, vaccine skeptical parents want to know if their child is "immune" after the first dose to avoid the second dose. In the usual healthy child, this should be discouraged for the following reasons. Read More

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Measles Experience, Practice, and Knowledge by Pediatricians in the Context of Resurgent US Outbreaks.

J Pediatr 2022 Jul 12;246:213-219.e1. Epub 2022 Apr 12.

Adult and Child Consortium for Health Outcomes Research and Delivery Science, University of Colorado Anschutz Medical Campus and Children's Hospital Colorado, Aurora, CO; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO.

Objective: To assess measles experience, practice, and knowledge by pediatricians in the context of resurgent US outbreaks in 2018-2019.

Study Design: A nationally representative network of pediatricians were surveyed by email and mail from January to April 2020.

Results: The response rate was 67% (297 of 444). Read More

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Immunological Memory and Affinity Maturation After Vaccination in Patients With Propionic Acidemia.

Front Immunol 2022 25;13:774503. Epub 2022 Mar 25.

Department of Child and Adolescent Health, Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

Earlier studies have recommended routine childhood immunization in patients with propionic acidemia (PA); however, the literature presents insufficient data on the response to vaccines, notably specific IgG concentrations and avidity maturation, after measles, mumps, rubella (MMR), and diphtheria/tetanus (DiphtTe) vaccinations in this population. In patients with PA, cellular and humoral changes of the immune system (e.g. Read More

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Inadequate protection against measles and rubella among pregnant women in Greece during the last measles outbreak.

J Infect 2022 Jun 7;84(6):e95-e97. Epub 2022 Apr 7.

Second Department of Pediatrics, National and Kapodistrian University of Athens, School of Medicine, 'P. & A. Kyriakou' Children's Hospital, Athens, Greece.

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Physician vaccination practices in mild to moderate inborn errors of immunity and retrospective review of vaccine completeness in IEI: results from the Canadian Immunization Research Network.

Allergy Asthma Clin Immunol 2022 Apr 9;18(1):32. Epub 2022 Apr 9.

Departments of Pediatrics and Community Health and Epidemiology, Canadian Center for Vaccinology, IWK Health Centre, Dalhousie University, Halifax, Canada.

Background And Objectives: Safety and effectiveness concerns may preclude physicians from recommending vaccination in mild/moderate inborn errors of immunity (IEI). This study describes attitudes and practices regarding vaccination among physicians who care for patients with mild/moderate B cell or mild/moderate combined immunodeficiencies (CID) and vaccination completeness among patients diagnosed with IEIs.

Methods: Canadian physicians caring for children with IEI were surveyed about attitudes and practices regarding vaccination in mild/moderate IEI. Read More

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Vaccination coverage rates and attitudes towards mandatory vaccinations among healthcare personnel in tertiary-care hospitals in Greece.

Expert Rev Vaccines 2022 Jun 13;21(6):853-859. Epub 2022 Apr 13.

Pathophysiology Department, Medical School, National and Kapodistrian University of Athens, and General Hospital of Athens Laiko, Athens, Greece.

Objectives: Our aim was to estimate vaccination and susceptibility rates against vaccine-preventable diseases among healthcare personnel (HCP) in eight hospitals.

Methods: Cross-sectional survey.

Results: A total of 1284 HCP participated (physicians: 31. Read More

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National rates and disparities in childhood vaccination and vaccine-preventable disease during the COVID-19 pandemic: English sentinel network retrospective database study.

Arch Dis Child 2022 Mar 31. Epub 2022 Mar 31.

Paediatrics, University of Oxford, Oxford, UK.

Objectives: To describe rates and variation in uptake of pneumococcal and measles, mumps and rubella (MMR) vaccines in children and associated change in vaccine-preventable diseases (VPDs) across the first and second waves of the COVID-19 pandemic.

Methods: Retrospective database study of all children aged <19 registered with a general practice in the Oxford Royal College of General Practitioners Research and Surveillance Centre English national sentinel surveillance network between 2 November 2015 and 18 July 2021.

Results: Coverage of booster dose of pneumococcal vaccine decreased from 94. Read More

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The Clinical and Economic Impact of Measles-Mumps-Rubella Vaccinations to Prevent Measles Importations From US Pediatric Travelers Returning From Abroad.

J Pediatric Infect Dis Soc 2022 Jun;11(6):257-266

Medical Practice Evaluation Center, Massachusetts General Hospital, Boston, Massachusetts, USA.

Background: Pediatric international travelers account for nearly half of measles importations in the United States. Over one third of pediatric international travelers depart the United States without the recommended measles-mumps-rubella (MMR) vaccinations: 2 doses for travelers ≥12 months and 1 dose for travelers 6 to <12 months.

Methods: We developed a model to compare 2 strategies among a simulated cohort of international travelers (6 months to <6 years): (1) No pretravel health encounter (PHE): travelers depart with baseline MMR vaccination status; (2) PHE: MMR-eligible travelers are offered vaccination. Read More

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Position statement of the Spanish Society of Pediatric Rheumatology on infection screening, prophylaxis, and vaccination of pediatric patients with rheumatic diseases and immunosuppressive therapies: Part 1 (screening).

Eur J Pediatr 2022 Jun 8;181(6):2343-2354. Epub 2022 Mar 8.

Department of Pediatrics, Infectious and Tropical Diseases, Hospital Universitario La Paz, and La Paz Research Institute (IdiPaz). CIBERINFEC. ISCIII, Madrid, Spain.

This study provides practical recommendations on infection screening in pediatric patients with immune-mediated rheumatic diseases and immunosuppressive therapies. For this reason, a qualitative approach was applied. A narrative literature review was performed via Medline. Read More

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Is aseptic meningitis following mumps vaccination underreported in Japan?

Pediatr Int 2022 Jan;64(1):e14968

Department of Pediatrics, National Hospital Organization Mie National Hospital, Tsu, Mie, Japan.

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January 2022

Improving Immunization Rates During the 2019 Measles Outbreak.

J Prim Care Community Health 2022 Jan-Dec;13:21501319211069271

University of Minnesota Medical School Twin Cities, Minneapolis, MN, USA.

In 2019, there were multiple outbreaks of measles in the United States. In the context of the public awareness of these outbreaks, we performed an intervention with the intent to improve the rate of measles immunization in our pediatric population. Pediatric patients that were lacking adequate measles immunization were identified by electronic medical record (EMR) survey. Read More

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February 2022

Evaluation of the effect of maternally derived antibody on response to MMR vaccine in Thai infants.

Vaccine 2022 03 5;40(10):1439-1447. Epub 2022 Feb 5.

MRC-University of Glasgow Centre for Virus Research, Bearsden Road, Glasgow G61 1QH, UK. Electronic address:

Background: Although the number of measles cases declined globally in response to anti-measles immunisation campaigns, measles has re-emerged. A review of current vaccination policies is required to improve measles elimination strategies.

Methods: A pseudotype-based virus neutralisation assay (PVNA) was used to measure neutralising antibody titres in serum samples collected from Thai infants at six timepoints before and after two-doses of MMR (1&2) vaccination (ClinicalTrials. Read More

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Medical factors associated with caregiver intention to vaccinate their children against COVID-19.

Vaccine X 2022 Apr 31;10:100144. Epub 2022 Jan 31.

Sidney Kimmel Medical College at Thomas Jefferson University, 833 Chestnut St, Philadelphia, PA 19107, USA.

Objective: To describe medical factors that are associated with caregiver intention to vaccinate their children against COVID-19.

Methods: We conducted a cross-sectional study of families receiving primary care in a mid-Atlantic pediatric healthcare system, linking caregiver-reported data from a survey completed March 19 to April 16, 2021 to comprehensive data from the child's EHR.

Results: 513 families were included (28% Black, 16% Hispanic, 44% public insurance, 21% rural, child age range 0-21 years). Read More

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Seroprevalence of mumps among children and adolescents in Thailand, 2020.

Vaccine 2022 02 22;40(8):1061-1064. Epub 2022 Jan 22.

Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Thammasat University, Thailand.

Thailand has implemented single-dose mumps-containing vaccines since 1997 and two doses since 2010. This study aimed to describe the seroprevalence of mumps among children who received one- or two-dose mumps vaccines. A cross-sectional study of 145 children (aged 3-9 years) and 422 adolescents (10-18 years) was conducted. Read More

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February 2022

The Cosmos Collaborative: A Vendor-Facilitated Electronic Health Record Data Aggregation Platform.

ACI open 2021 Jan;5(1):e36-e46

Center for Clinical Informatics Research and Education, The MetroHealth System, Cleveland, Ohio, United States.

Objective: Learning healthcare systems use routinely collected data to generate new evidence that informs future practice. While implementing an electronic health record (EHR) system can facilitate this goal for individual institutions, meaningfully aggregating data from multiple institutions can be more empowering. Cosmos is a cross-institution, single EHR vendor-facilitated data aggregation tool. Read More

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January 2021

50 Years Ago in TheJournalofPediatrics: Virus-Induced Suppression of Cellular Immunity.

Authors:
Sarah S Long

J Pediatr 2022 Feb;241:76

Drexel University College of Medicine, Philadelphia, Pennsylvania.

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February 2022

Annual trends in adverse events following mumps vaccination in Japan: A retrospective study.

Vaccine 2022 02 17;40(7):988-993. Epub 2022 Jan 17.

Department of Public Health, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka-city, Osaka 545-8585, Japan; Clinical Epidemiology Research Center, SOUSEIKAI, 3-5-1, Kashii-Teriha Higashi-ku, Fukuoka 813-0017, Japan.

Background: In Japan, a monovalent mumps vaccine is provided on a voluntary basis. Due to public concerns over post-vaccination aseptic meningitis, the vaccination coverage is not high enough. The present study investigated the incidence of adverse events, including aseptic meningitis, after Torii strain-derived mumps vaccination. Read More

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February 2022

Indirect effects of the covid-19 pandemic on childhood infection in England: population based observational study.

BMJ 2022 01 12;376:e067519. Epub 2022 Jan 12.

Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.

Objective: To assess the impact of the covid-19 pandemic on hospital admission rates and mortality outcomes for childhood respiratory infections, severe invasive infections, and vaccine preventable disease in England.

Design: Population based observational study of 19 common childhood respiratory, severe invasive, and vaccine preventable infections, comparing hospital admission rates and mortality outcomes before and after the onset of the pandemic in England.

Setting: Hospital admission data from every NHS hospital in England from 1 March 2017 to 30 June 2021 with record linkage to national mortality data. Read More

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January 2022

Factors associated between behavior of administrating or recommending mumps vaccine and primary care physicians' knowledge about vaccination: A nationwide cross-sectional study in Japan.

J Gen Fam Med 2022 Jan 20;23(1):9-18. Epub 2021 Jun 20.

Department of General Medicine Osaka Medical and Pharmaceutical University Takatsuki Japan.

Background: In Japan, the mumps-containing vaccine was withdrawn from routine vaccination in 1993, and it became a voluntary vaccination. This study aimed to evaluate the association between the physicians' knowledge about vaccinations and the administration or recommendation of the mumps vaccine.

Methods: We conducted a nationwide cross-sectional study targeting primary care physicians (PCPs) in Japan. Read More

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January 2022

Control of a nosocomial measles outbreak among previously vaccinated adults in a population with high vaccine coverage: Korea, 2019.

Eur J Clin Microbiol Infect Dis 2022 Mar 9;41(3):455-466. Epub 2022 Jan 9.

Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.

We describe a measles outbreak among previously vaccinated healthcare workers (HCWs) and inpatients and the control measures implemented at a tertiary care hospital in 2019. Case-patients were laboratory-confirmed measles with throat swabs tested by quantitative polymerase chain reactions (PCR), during April-May 2019. Medical histories and documented immunization records were obtained. Read More

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Live virus vaccination following pediatric liver transplantation: Outcomes from two academic children's hospitals.

Am J Transplant 2022 04 22;22(4):1201-1212. Epub 2022 Jan 22.

Division of Infectious Diseases, Ann & Robert H. Lurie Children's Hospital of Chicago and Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

Pediatric liver transplant (LT) recipients are often transplanted at a young age, precluding them from receiving live virus vaccinations (LVV) such as varicella (VZV) vaccine and measles, mumps and rubella. This places them at profound risk for vaccine preventable illness. We sought to detail safety of vaccination. Read More

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A National Cross-Sectional Study from the Republic of Kosovo on Lot Quality Assurance Sampling (LQAS) to Evaluate the Vaccination Status of Children Between 12 and 24 Months of Age During 2018 to 2020.

Med Sci Monit Basic Res 2021 Dec 27;27:e934194. Epub 2021 Dec 27.

Department of Pediatrics, Clinical Hospital Service University of Kosovo (SHSKUK), Prishtina, Kosovo.

BACKGROUND In the Republic of Kosovo, full vaccination status in children under age 2 years includes: 1 dose of Bacillus Calmette-Guerin (BCG) hepatitis B virus (HBV) vaccine; 3 doses of diphtheria, tetanus, pertussis, hepatitis B, polio, and Haemophilus influenzae type b (DTaP-HB-IPV-Hib) vaccine; 3 doses of inactivated polio vaccine (IPV); and 1 dose of measles, mumps, and rubella (MMR) vaccine. Lot quality assurance sampling (LQAS) is a method used to assess the performance of health quality indicators. MATERIAL AND METHODS A national cross-sectional study with children aged between 12 and 24 months from Kosovo was performed between 2018 and 2020. Read More

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December 2021