4,274 results match your criteria Pediatrics International[Journal]


A case review of neonates with elevated C-reactive protein in umbilical cord blood.

Pediatr Int 2019 Apr 16. Epub 2019 Apr 16.

Department of Neonatal Intensive Care Unit, Nara Prefecture General Medical Center, Nara, Japan.

Objectives: C-reactive protein (CRP) has limited placental transportability. Relying on CRP level in umbilical cord blood alone is an inaccurate way to predict early-onset neonatal sepsis, and we retrospectively reviewed the clinical courses of neonates with elevated CRP levels in umbilical cord blood.

Methods: This study was a retrospective case review of neonates with elevated CRP levels in umbilical cord blood (>0. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13866
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http://dx.doi.org/10.1111/ped.13866DOI Listing
April 2019
2 Reads

Serum high mobility group box-1 and cytokine profiles in a leukemoid reaction.

Pediatr Int 2019 Apr 17. Epub 2019 Apr 17.

Shino-Test Corporation, Sagamihara, Kanagawa, Japan.

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http://dx.doi.org/10.1111/ped.13797DOI Listing

Cladribine-related myelodysplastic syndrome in Langerhans cell histiocytosis.

Pediatr Int 2019 Apr 17. Epub 2019 Apr 17.

Department of Pediatrics, Jichi Medical University School of Medicine, Shimotsuke, Tochigi, Japan.

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http://dx.doi.org/10.1111/ped.13792DOI Listing

Heart failure and coronary ischemia in a neonate with right coronary artery fistula.

Pediatr Int 2019 Apr 16. Epub 2019 Apr 16.

Department of Pediatrics, Asahikawa Kosei General Hospital, Asahikawa, Hokkaido, Japan.

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http://dx.doi.org/10.1111/ped.13807DOI Listing
April 2019
3 Reads

Long-lasting low NK cell activity after hemophagocytic lymphohistiocytosis in an infant with spontaneous recovery.

Pediatr Int 2019 Apr 16. Epub 2019 Apr 16.

Department of Pediatrics, Kanazawa University, Kanazawa, Ishikawa, Japan.

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http://dx.doi.org/10.1111/ped.13803DOI Listing

Hyponatremia secondary to severe atopic dermatitis in early infancy.

Pediatr Int 2019 Apr 15. Epub 2019 Apr 15.

Department of Allergy, Kanagawa Children's Medical Center, Yokohama, Japan.

Background: Infants with atopic dermatitis who developed hyponatremia and hyperkalemia with raised aldosterone level have been repeatedly described in Japanese domestic literatures. However, similar reports from other countries are scarce.

Methods: Including our experiences, we collected reports of atopic dermatitis complicated with hyponatremia (≤130 mEq/L), written either in English or in Japanese, to delineate the characteristics and to elucidate the pathophysiology of this condition. Read More

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http://dx.doi.org/10.1111/ped.13865DOI Listing
April 2019
3 Reads

Plastic bronchitis: Three cases caused by influenza B virus Yamagata lineage.

Pediatr Int 2019 Apr 14. Epub 2019 Apr 14.

Department of Emergency and Critical Care Medicine, Seirei Hamamatsu General Hospital, Hamamatsu City, Shizuoka, Japan.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13799
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April 2019
2 Reads

Urolithiasis with overdiagnosed nutcracker syndrome in a pediatric patient.

Pediatr Int 2019 Apr 14. Epub 2019 Apr 14.

Department of Pediatrics, Suwa Central Hospital, Chino, Nagano, Japan.

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http://dx.doi.org/10.1111/ped.13796DOI Listing

Thymitis in chronic granulomatous disease.

Pediatr Int 2019 Apr 14. Epub 2019 Apr 14.

Division of Immunology, National Center for Child Health and Development, Tokyo, Japan.

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http://dx.doi.org/10.1111/ped.13810DOI Listing

Spontaneous pneumoperitoneum in two extremely preterm infants during nasal intermittent positive pressure ventilation.

Pediatr Int 2019 Apr 14. Epub 2019 Apr 14.

Department of Pediatric Surgery, Keimyung University, Dongsan Medical Center, Daegu, South Korea.

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http://dx.doi.org/10.1111/ped.13805DOI Listing
April 2019
1 Read

Febrile seizures with leukocytosis as a predictor for occult bacteremia.

Pediatr Int 2019 Apr 12. Epub 2019 Apr 12.

Division of Infectious Diseases, Department of Medical Specialties, National Center for Child Health and Development, Tokyo, JPN.

Background: Febrile children 3-36 months old, who had a body temperature > 39 °C and white blood cell count > 15,000/mm were known to be at risk for occult pneumococcal bacteremia (OPB) in the pre-pneumococcal conjugate vaccine (PCV) era. However, the positive predictive value of this criteria decreased dramatically after introduction of PCV, which indicates a need for alternative criteria. Previous studies demonstrated a high rate of febrile seizures in children with OPB, suggesting that screening may still be practical in this population. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13862
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http://dx.doi.org/10.1111/ped.13862DOI Listing
April 2019
1 Read

Seasonality differs by IVIG responsiveness in patients with Kawasaki disease.

Pediatr Int 2019 Apr 12. Epub 2019 Apr 12.

Division of Public Health, Center for Community Medicine, Jichi Medical University, Tochigi, Japan.

Background: Evidence suggests that seasonal variation in the onset of Kawasaki Disease (KD) exists worldwide. However, whether a seasonal component to successful intravenous immunoglobulin (IVIG) therapy exists in KD-positive children is unknown. We addressed this question by focusing on patients with primary onset KD who were non-responsive to IVIG treatment by analyzing the large nationwide Japanese KD survey datasets from 2009-2016. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13863
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http://dx.doi.org/10.1111/ped.13863DOI Listing
April 2019
7 Reads

Food protein-induced enterocolitis syndrome caused by egg yolk in an infant.

Pediatr Int 2019 Apr 11. Epub 2019 Apr 11.

Department of Pediatrics, Higashiosaka City Medical Center, Osaka, Japan.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13785
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http://dx.doi.org/10.1111/ped.13785DOI Listing
April 2019
3 Reads

Killer-cell immunoglobulin-like receptor ligand mismatch cord blood transplantation in high-risk neuroblastoma.

Pediatr Int 2019 Apr 11. Epub 2019 Apr 11.

Department of Pediatrics, Showa University Fujigaoka Hospital, Japan.

Background: The prognosis of high-risk neuroblastoma-stage 4 with bone marrow metastasis, MYCN amplified, or refractory neuroblastoma is poor. To date, no standard treatment has been established. In an attempt to measure the survival rates of four selected cases, we challenged the killer-cell immunoglobulin-like receptor ligand mismatch cord blood transplantation in the graft-versus-host disease with reduced intensity conditioning. Read More

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http://dx.doi.org/10.1111/ped.13861DOI Listing
April 2019
1 Read

Influence of GST polymorphisms on busulfan pharmacokinetics in Japanese children.

Pediatr Int 2019 Apr 9. Epub 2019 Apr 9.

Department of Pediatrics and Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.

Background: Fatal adverse effects or relapse can occur with excessive or insufficient busulfan exposure in hematopoietic stem cell transplantation. As busulfan is mainly metabolized by glutathione S-transferase (GST), we investigated the influence of GST gene polymorphisms on busulfan pharmacokinetics in Japanese pediatric patients.

Methods: Blood samples were taken from patients receiving high-dose intravenous busulfan as the first dose. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13859
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http://dx.doi.org/10.1111/ped.13859DOI Listing
April 2019
8 Reads

30-day mortality after neonatal laparotomy in a Chinese tertiary hospital.

Pediatr Int 2019 Apr 8. Epub 2019 Apr 8.

Department of Pediatric Surgery, Peking University First Hospital, Beijing, China.

Background: No data are now available on the prevalence of mortality in neonates for major surgery such as laparotomy in China.

Methods: In a tertiary general hospital, 142 newborns subjected to laparotomy for a variety of surgical conditions in the past six years were included in this study in Beijing, China. Pre-, intra-, and postoperative variables potentially predictive of postoperative 30-day mortality were collected and compared between the survival and deceased newborns. Read More

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http://dx.doi.org/10.1111/ped.13858DOI Listing

Use of dried urine spots for screening of inborn errors of bile acid synthesis.

Pediatr Int 2019 Mar 28. Epub 2019 Mar 28.

Junshin Clinic BA Institute, 2-1-22 Haramachi, Meguro-ku, Tokyo, 152-0011, Japan.

Background: In pediatric patients with cholestasis of unknown cause, inborn errors of bile acid (BA) synthesis (IEBAS) may be considered. For the initial screening for IEBAS, clarification of the urine BA profile is essential. However, the transportation of urine in a frozen state via air delivery is laborious and costly. Read More

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http://dx.doi.org/10.1111/ped.13852DOI Listing

Sivelestat Sodium Hydrate Treatment for refractory Kawasaki Disease Patients.

Pediatr Int 2019 Mar 27. Epub 2019 Mar 27.

Department of Pediatrics, Graduate School of Medicine, Chiba University.

Background: There are still no definite treatments for refractory Kawasaki disease (KD). In this pilot study, we evaluated the safety and efficacy of a new protocol consisting of sivelestat sodium hydrate (SSH) combined with additional intravenous immune globulin (IVIG) for KD patients who were resistant to initial IVIG therapy.

Methods: This study is a prospective non-randomized, open-label and single-arm study undertaken in a population of refractory KD patients at Chiba University Hospital from December 2006 to March 2016. Read More

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http://dx.doi.org/10.1111/ped.13851DOI Listing

Rare clinical condition during Wilms' tumor treatment: Testicular metastasis.

Pediatr Int 2019 Mar;61(3):310-311

Department of Pediatric Oncology, Faculty of Medicine, Kocaeli University, Izmit, Kocaeli, Turkey.

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http://dx.doi.org/10.1111/ped.13769DOI Listing

Enigma of myeloid proliferation in Down syndrome.

Authors:
Daisuke Hasegawa

Pediatr Int 2019 Mar;61(3):221

Department of Pediatrics, St Luke's International Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1111/ped.13794DOI Listing

Balloon angioplasty in a pediatric patient with nutcracker syndrome.

Pediatr Int 2019 Mar 18;61(3):300-301. Epub 2019 Mar 18.

Department of Pediatrics, Faculty of Medicine, Kagawa University, Kagawa, Japan.

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http://dx.doi.org/10.1111/ped.13784DOI Listing

Cefmetazole for ESBL-producing Enterobacteriaceae in Pediatric Pyelonephritis.

Pediatr Int 2019 Mar 25. Epub 2019 Mar 25.

Division of Infectious Diseases, Department of Pediatrics, Tokyo Metropolitan Children's Medical Center, 2-8-29, Musashidai, Fuchu-shi, Tokyo, 183-8561, Japan.

Background: Pyelonephritis caused by extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae are an urgent problem in pediatrics. Although carbapenem is the standard therapy for infections caused by ESBL-producing Enterobacteriaceaes, some cephamycins, including cefmetazole, are stable against hydrolysis by ESBL. However, there are few reports of the use of cefmetazole in children. Read More

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http://dx.doi.org/10.1111/ped.13847DOI Listing
March 2019
1 Read

Japanese Clinical Practice Guidelines for Sacrococcygeal Teratoma, 2017.

Pediatr Int 2019 Mar 22. Epub 2019 Mar 22.

Department of Pediatric Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Background: Sacrococcygeal teratoma (SCT) is the most common extragonadal germ cell tumor in neonates and infants. Although most cases of infantile SCT are benign tumors by nature, some develop into extremely large lesions, leading to massive bleeding, high-output heart failure, disseminated intravascular coagulation, and even fatal outcomes during the neonatal period. In addition, some cases may present with tumor recurrence, malignant transformation, long-term sequelae (including bladder and bowel dysfunction) and lower leg palsy during the long-term follow-up. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13844
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http://dx.doi.org/10.1111/ped.13844DOI Listing
March 2019
4 Reads

Prevalence of infant and maternal anemia during the lactation period in Japan.

Pediatr Int 2019 Mar 21. Epub 2019 Mar 21.

Akitsu Children's Clinic, 4-31-16 Akitsu-cho, Higashimurayama, Tokyo, Japan.

Background: The perinatal period is associated with a high risk of infant anemia. The aim of the present study was to determine the prevalence of infant and maternal anemia during the late lactation period and the risk factors for anemia in Japan.

Methods: This retrospective cohort study was based on data from health checkups of healthy infants at 6-7 and 9-10 months of age and their mothers who visited Akitsu Children's Clinic between September 2013 and August 2015. Read More

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http://dx.doi.org/10.1111/ped.13833DOI Listing
March 2019
2 Reads

The Impact of Nutrition in the Congenital Diaphragmatic Hernia Treatment.

Pediatr Int 2019 Mar 19. Epub 2019 Mar 19.

Department of Pediatric Surgery, Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, 260-8677, Japan.

Background: The optimum enteral (EN) and parenteral nutrition (PN) regimes during acute management of congenital diaphragmatic hernia (CDH) remain unclear. We aimed to examine the effects of EN and PN on weight gain in CDH patients.

Methods: Multicenter retrospective cohort study including neonates with CDH (born 2006-2010; n = 105) who survived to discharge was conducted. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13837
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http://dx.doi.org/10.1111/ped.13837DOI Listing
March 2019
10 Reads

Indication for voiding cystourethrography during first urinary tract infection.

Pediatr Int 2019 Mar 19. Epub 2019 Mar 19.

Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.

Background: There is confusion surrounding the precise indications for voiding cystourethrography (VCUG) during the assessment of vesicoureteral reflex (VUR) after a first febrile urinary tract infection (UTI). The aim of this study was to determine the combination of clinical, laboratory and ultrasonography factors which correlated with grades IV-V VUR among young children with a first febrile UTI.

Methods: Children 0-24 months of age who were brought to the emergency department at National Center for Child Health and Development with the diagnosis of first time febrile UTI from March 2004, to May 2011, were included. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ped.13835
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http://dx.doi.org/10.1111/ped.13835DOI Listing
March 2019
12 Reads

Non-immune hydrops fetalis neonate born to a mother with yellow nail syndrome.

Pediatr Int 2019 Mar 18;61(3):313-315. Epub 2019 Mar 18.

Department of Pediatrics, Oita University Faculty of Medicine, Oita, Japan.

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http://dx.doi.org/10.1111/ped.13771DOI Listing

The efficacy of low-dose propranolol treatment in infantile hemangioma and the results of intralesional bleomycin injection in patients unresponsive to propranolol.

Pediatr Int 2019 Mar 12. Epub 2019 Mar 12.

Division of Pediatric Hematology/Onkology, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir, TURKEY.

Background: Infantile hemangioma (IH) is the most common form of benign childhood vascular tumors. Mostly resolve spontaneously; however, treatment is recommended in patients who develop complication. Propranolol is recommended as first-line therapy by authors, while the treatment of choice in patients who are unresponsive to first-line therapy depends on the clinical experiences of each center. Read More

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http://dx.doi.org/10.1111/ped.13830DOI Listing

Registration-directed phase 1/2 trial of irinotecan for pediatric solid tumors.

Pediatr Int 2019 Mar 11. Epub 2019 Mar 11.

Department of Pediatric Surgery, University of Tsukuba School of Medicine, Ibaraki, Japan.

Background: Although irinotecan hydrochloride (IRI) is a promising chemotherapeutic agent for pediatric solid tumors, its indications had been off-label in the US, EU or Japan. Therefore, we conducted a phase 1/2 trial of IRI monotherapy in a registration-directed setting.

Methods: Children aged 2 to 18 years with solid tumors which were either refractory to or relapsed after standard chemotherapy were enrolled. Read More

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http://dx.doi.org/10.1111/ped.13826DOI Listing
March 2019
1 Read

Predicting Serious Bacterial Infections in Febrile Young Infants Utilizing Body Temperature.

Pediatr Int 2019 Mar 12. Epub 2019 Mar 12.

Division of Pediatric Emergency Medicine, Department of Pediatric Emergency and Critical Care Medicine, Tokyo Metropolitan Children's Medical Center, 2-8-29, Musashidai, Fuchu, Tokyo, 183-8561, Japan.

Background: Febrile young infants have a high risk of serious infection. While measuring vital sign parameters can serve as a rapid and effective assessment in these patients, their predictive value for serious bacterial infections has not been fully investigated.

Methods: This retrospective observational study enrolled febrile (>38. Read More

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http://doi.wiley.com/10.1111/ped.13831
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http://dx.doi.org/10.1111/ped.13831DOI Listing
March 2019
2 Reads

Tuberous sclerosis presenting with tachycardia as an autonomic phenomenon of epilepsy.

Pediatr Int 2019 Mar 10;61(3):307-309. Epub 2019 Mar 10.

Department of Pediatrics, Kakogawa Central City Hospital, Kakogawa, Hyogo, Japan.

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http://doi.wiley.com/10.1111/ped.13782
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http://dx.doi.org/10.1111/ped.13782DOI Listing
March 2019
3 Reads

Hemodynamics of infants exhibiting strong fluctuations of internal cerebral vein.

Pediatr Int 2019 Mar 10. Epub 2019 Mar 10.

Department of Neonatology, Aomori Prefectural Central Hospital, Aomori, 030-8553, Japan.

Background: There is a high incidence of intraventricular hemorrhage in extremely low birth weight (ELBW) infants of low gestational age who exhibit high-grade fluctuations in the perfusion waveform of the internal cerebral vein. This study investigated changes in the hemodynamic status of ELBW infants during initial strong fluctuations in the perfusion waveform of the internal cerebral vein.

Methods: We evaluated the perfusion waveform of the internal cerebral vein in 192 ELBW infants from birth, every 8 h for a total of 120 h. Read More

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http://dx.doi.org/10.1111/ped.13828DOI Listing
March 2019
1 Read

Exclusive breastfeeding and postnatal changes in blood sodium, ketone, and glucose levels.

Pediatr Int 2019 Mar 10. Epub 2019 Mar 10.

Department of Pediatrics, Toyama Prefectural Central Hospital.

Background: Blood sodium and ketone levels are parameters of dehydration and fasting, respectively. However, little is known about the postnatal changes in these parameters that occur in healthy, term, exclusively breastfed neonates.

Methods: Capillary blood sodium, beta-hydroxybutyrate (βOHB), and glucose levels in 628 samples obtained from 392 healthy, term, exclusively breastfed neonates during the first 12 to 143 hours of life were examined. Read More

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http://dx.doi.org/10.1111/ped.13824DOI Listing
March 2019
2 Reads

Low-dose i.v. urokinase for coronary thrombosis in Kawasaki disease.

Pediatr Int 2019 Mar 10;61(3):302-303. Epub 2019 Mar 10.

Department of Child Health, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.

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http://dx.doi.org/10.1111/ped.13783DOI Listing
March 2019
2 Reads

Cervical accessory trachea with mediastinal cystic lung tissue.

Pediatr Int 2019 Mar 10;61(3):303-306. Epub 2019 Mar 10.

Department of Radiology, Kobe Children's Hospital, Kobe, Japan.

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http://dx.doi.org/10.1111/ped.13767DOI Listing

Green LED phototherapy for neonatal hyperbilirubinemia: A randomized controlled trial.

Pediatr Int 2019 Mar 5. Epub 2019 Mar 5.

Department of Pediatrics, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Background: The main photochemical pathway in phototherapy for neonatal hyperbilirubinemia is the production and elimination of cyclobilirubin, which is a structural photoisomer of bilirubin and is most efficiently produced by green light. However, green light-emitting diode (LED) phototherapy has not been evaluated in the clinical setting because it is not recommended in American Academy of Pediatrics guidelines. We aimed to compare the efficacy of green LED phototherapy and blue LED phototherapy in patients with neonatal hyperbilirubinemia. Read More

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http://dx.doi.org/10.1111/ped.13821DOI Listing

Novel non-invasive modalities for presurgical evaluation in focal epilepsy.

Pediatr Int 2019 Mar 4;61(3):319-321. Epub 2019 Mar 4.

Department of Pediatrics, Nagoya University Graduate School of Medicine, Aichi, Japan.

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http://dx.doi.org/10.1111/ped.13793DOI Listing
March 2019
5 Reads

High prevalence of underlying orthostatic proteinuria in young Japanese women.

Authors:
Hiroshi Tanaka

Pediatr Int 2019 Mar 4;61(3):306-307. Epub 2019 Mar 4.

Department of School Health Science, Hirosaki University Faculty of Education, Hirosaki, Japan.

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http://dx.doi.org/10.1111/ped.13781DOI Listing
March 2019
1 Read

Assessment of ovarian reserve by serum AMH levels after ovarian torsion surgery.

Pediatr Int 2019 Mar 2. Epub 2019 Mar 2.

Department of Pediatric Surgery, Istanbul Medeniyet University, Goztepe Training and Research Hospital, Istanbul, Turkey.

Background: Determination of ovarian reserve by serum anti-Müllerian hormone (AMH) levels in children who underwent either ovarian preserving surgery or oophorectomy because of ovarian torsion.

Methods: Patients operated on for unilateral ovarian torsion over ten years were contacted for the study with an ethical committee approval. Seventeen patients agreed to be included. Read More

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http://dx.doi.org/10.1111/ped.13818DOI Listing
March 2019
2 Reads

Histological significance of hepatitis-like findings in biliary atresia: An analysis of 34 Japanese cases.

Pediatr Int 2019 Feb 27. Epub 2019 Feb 27.

Department of Pediatric Surgery, Ibaraki Children's Hospital, Mito, Ibaraki, Japan.

Background: Hepatocellular injury including multinuclear changes are common histological features in biliary atresia (BA), as well as in neonatal hepatitis. To date, however, no reports have examined how those findings correlate with the prognosis of BA. We clarified the clinical implications of hepatitis-related changes in BA on histological analysis. Read More

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http://dx.doi.org/10.1111/ped.13816DOI Listing
February 2019

Selective laser trabeculoplasty for steroid glaucoma in a child with leukemia.

Pediatr Int 2019 Feb 7;61(2):208-210. Epub 2019 Feb 7.

Department of Pediatric Hematology and Oncology, Okayama University Hospital, Okayama, Japan.

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http://dx.doi.org/10.1111/ped.13754DOI Listing
February 2019
1 Read

How to manage pediatric oncologic emergencies: Imaging diagnosis.

Authors:
Motohiro Kato

Pediatr Int 2019 02;61(2):121

Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.

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http://doi.wiley.com/10.1111/ped.13790
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http://dx.doi.org/10.1111/ped.13790DOI Listing
February 2019
2 Reads

Pediatric phantom tumor caused by cardiac catheterization.

Pediatr Int 2019 02;61(2):214

Department of Pediatrics, Nara Medical University, Kashihara, Nara, Japan.

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http://dx.doi.org/10.1111/ped.13750DOI Listing
February 2019
2 Reads

Coma and seizure caused by an afloqualone overdose.

Pediatr Int 2019 Feb;61(2):212-213

Department of Neurology, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.

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http://doi.wiley.com/10.1111/ped.13777
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http://dx.doi.org/10.1111/ped.13777DOI Listing
February 2019
6 Reads

Splenic torsion and polysplenia syndrome in a 10-year-old girl.

Pediatr Int 2019 Feb;61(2):192-193

National Hospital Organization Fukuyama Medical Center, Fukuyamashi, Hiroshima, Japan.

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http://dx.doi.org/10.1111/ped.13760DOI Listing
February 2019
1 Read

ATP7A mutations in 66 Japanese patients with Menkes disease and carrier detection: A gene analysis.

Pediatr Int 2019 Feb 26. Epub 2019 Feb 26.

Department of Physiology, Toho University School of Medicine, Tokyo, Japan.

Background: Menkes disease (MNK; MIN 309400) is an X-linked recessive lethal disorder of copper metabolism caused by mutations in ATP7A (MIM 300011), which encodes a transmembrane copper-transporting P-type ATPase. This study assessed mutations in ATP7A in Japanese patients with MNK and their families using gene analysis.

Methods: A total of 66 patients with MNK born between 1975 and 2013 in Japan were investigated in this study. Read More

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http://doi.wiley.com/10.1111/ped.13817
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http://dx.doi.org/10.1111/ped.13817DOI Listing
February 2019
2 Reads

Zoledronic acid for relapsed Langerhans cell histiocytosis with isolated skull bone lesion.

Pediatr Int 2019 Mar 21;61(3):315-317. Epub 2019 Feb 21.

Department of Pediatrics, Hirosaki University School of Medicine, Hirosaki, Japan.

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http://dx.doi.org/10.1111/ped.13774DOI Listing
March 2019
1 Read

Bronchopulmonary dysplasia in very preterm infants: Outcome up to preschool age, in a single center of Austria.

Pediatr Int 2019 Feb 22. Epub 2019 Feb 22.

Division of Neonatology, Department of Pediatrics and Adolescence Medicine, Medical University of Graz, Graz, Austria.

Background: Bronchopulmonary dysplasia (BPD) is the most frequent chronic lung disease in infancy and is associated with neonatal comorbidity and impairment in pulmonary and neurodevelopmental (ND) long-term outcome.

Methods: This was a retrospective, single-center, cohort study to compare a cohort of very preterm infants (gestational age [GA], 24 -28 weeks) with BPD (n = 44), with a cohort of GA-matched preterm infants without BPD (n = 44) with regard to neonatal morbidity, incidence of lower respiratory tract infection (LRTI), ND outcome and growth to 2 years' corrected age (CA) and preschool age.

Results: Bronchopulmonary dysplasia (incidence, 11. Read More

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http://dx.doi.org/10.1111/ped.13815DOI Listing
February 2019
1 Read

Nationwide epidemiologic survey of Kawasaki disease in Japan, 2015-2016.

Pediatr Int 2019 Feb 20. Epub 2019 Feb 20.

Department of Public Health, Jichi Medical University, Shimotsuke, Tochigi, Japan.

Background: Approximately 50 years have passed since Kawasaki disease (KD) was first reported. The KD nationwide survey began in 1970. Although >360 000 cases have already been reported in Japan, the cause is still unknown. Read More

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http://dx.doi.org/10.1111/ped.13809DOI Listing
February 2019
1 Read
0.731 Impact Factor