11,289 results match your criteria Pediatrics Gastroenteritis

Comparison Of Efficacy Of Yogurt Versus Probiotics For The Management Of Acute Diarrhoea.

J Ayub Med Coll Abbottabad 2022 Apr-Jun;34(2):309-312

THQ Hospital, Saraialamgir, Pakistan.

Background: The advantages of probiotic administration for acute diarrhoea are mainly shorter duration of symptoms as well as reduced number of stools per day while use of traditional yogurt has similar results. So, this study was conducted to compare the efficacy of yogurt with probiotic in children with acute gastroenteritis.

Methods: This randomized controlled trial was conducted at department of Paediatrics, Children Hospital, Pakistan Institute of Medical Sciences, Islamabad over 1 year. Read More

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Outcomes and predictors of early emergency department discharge among children with acute gastroenteritis and moderate dehydration.

Int J Pediatr Adolesc Med 2022 Mar 11;9(1):27-31. Epub 2021 Mar 11.

Department of Biostatistics and Bioinformatics, King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.

Background: Gastroenteritis is one of the most common diseases that affects children and remains a leading cause of morbidity and mortality around the world. There is conflicting evidence regarding the effect of rapid intravenous fluid regimen on the clinical outcome of patients with acute gastroenteritis. This study aimed to assess the current practice of intravenous hydration on the clinical outcomes of pediatric patients with acute gastroenteritis and determine the predictive factors for early discharge and emergency department (ED) revisit. Read More

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Hyaluronic Acid 35 kDa Protects against a Hyperosmotic, Formula Feeding Model of Necrotizing Enterocolitis.

Nutrients 2022 Apr 24;14(9). Epub 2022 Apr 24.

Department of Pediatrics, Division of Neonatology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA.

Necrotizing enterocolitis (NEC), an inflammatory disease of the intestine, is a common gastrointestinal emergency among preterm infants. Intestinal barrier dysfunction, hyperactivation of the premature immune system, and dysbiosis are thought to play major roles in the disease. Human milk (HM) is protective, but the mechanisms underpinning formula feeding as a risk factor in the development of NEC are incompletely understood. Read More

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Infections or Vaccines Associated with Finkelstein-Seidlmayer Vasculitis: Systematic Review.

Clin Rev Allergy Immunol 2022 May 12. Epub 2022 May 12.

Pediatric Cardiology Unit, Department of Pediatrics, Centre Hospitalier Universitaire Vaudois and University of Lausanne, Lausanne, Switzerland.

Finkelstein-Seidlmayer vasculitis, also referred to as acute hemorrhagic edema of young children, is a rare small-vessel leukocytoclastic vasculitis. This condition is skin-limited, mainly affects infants up to 2 years of age and spontaneously remits. It has been suggested that an infection or a vaccine precede (by ≤ 14 days) this vasculitis. Read More

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ACR Appropriateness Criteria® Crohn Disease-Child.

J Am Coll Radiol 2022 May;19(5S):S19-S36

Specialty Chair, Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.

Crohn disease is an inflammatory condition of the gastrointestinal tract with episodes of exacerbation and remission occurring in children, adolescents, and adults. Crohn disease diagnosis and treatment depend upon a combination of clinical, laboratory, endoscopic, histological, and imaging findings. Appropriate use of imaging provides critical information in the settings of diagnosis, assessment of acute symptoms, disease surveillance, and therapy monitoring. Read More

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Differentiating Clinical Characteristics Between Necrotizing Enterocolitis and Food Protein-induced Enterocolitis When Both have Pneumatosis Intestinalis: A Single-centre Study.

J Coll Physicians Surg Pak 2022 May;32(5):646-651

Chongqing Key Laboratory of Pediatrics, Chongqing, China.

Objective: To compare the clinical characteristics of necrotizing enterocolitis (NEC) and food protein-induced enterocolitis (FPIES) when both have pneumatosis intestinalis (PI) and to identify them.

Study Design:  Analytical study.

Place And Duration Of Study:  Department of Neonatology, Children's Hospital of Chongqing Medical University, Chongqing, China, from January to December 2019. Read More

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High frequency of antimicrobial resistance and virulence gene in Shigella species isolated from pediatric patients in an Iranian Referral Hospital.

Acta Biomed 2022 May 11;93(2):e2022027. Epub 2022 May 11.

1- Pediatric Infectious Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Background: Shigella is a main cause of gastroenteritis and it is responsible for 5 to 10 % of diarrhea through the world. The aims of this study were to assess the antibiotic susceptibility pattern and the presence of 3 common virulence genes (sigA, virF, invE) of Shigella strains isolated from patients with gastroenteritis in Children's Medical Center Hospital, Tehran, Iran.

Methods: Over a period of 15 months, all Shigella species collected from the patients with gastroenteritis were entered to the study. Read More

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Whole-exome sequencing in a subject with fluctuating neuropsychiatric symptoms, immunoglobulin G1 deficiency, and subsequent development of Crohn's disease: a case report.

J Med Case Rep 2022 May 11;16(1):187. Epub 2022 May 11.

Department of Pediatrics, Saint Peter's University Hospital (SPUH), New Brunswick, USA.

Background: Mutations or polymorphisms of genes that are associated with inflammasome functions are known to predispose individuals to Crohn's disease and likely affect clinical presentations and responses to therapeutic agents in patients with Crohn's disease. The presence of additional gene mutations/polymorphisms that can modify immune responses may further affect clinical features, making diagnosis and management of Crohn's disease even more challenging. Whole-exome sequencing is expected to be instrumental in understanding atypical presentations of Crohn's disease and the selection of therapeutic measures, especially when multiple gene mutations/polymorphisms affect patients with Crohn's disease. Read More

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Application of coagulation parameters at the time of necrotizing enterocolitis diagnosis in surgical intervention and prognosis.

BMC Pediatr 2022 05 10;22(1):259. Epub 2022 May 10.

Department of General & Neonatal Surgery, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Pediatrics, Chongqing, China.

Purpose: It has been shown that abnormalities of coagulation and fibrinolysis system are involved in the pathogenesis of necrotizing enterocolitis (NEC), but not well studied challenge in the context of early detection of disease progression. The present study mainly explores the predictive significance of coagulation parameters at the time of NEC diagnosis in identifying the patients who eventually received surgery and/or NEC-related deaths.

Methods: The retrospective study of 114 neonates with NEC was conducted with assessments of demographic data, laboratory results at the time of NEC diagnosis, treatment methods and prognosis. Read More

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Trends in Management of Children With Acute Gastroenteritis in US Emergency Departments.

JAMA Netw Open 2022 May 2;5(5):e2211201. Epub 2022 May 2.

Sections of Pediatric Emergency Medicine and Gastroenterology, Departments of Pediatrics and Emergency Medicine, Alberta Children's Hospital Research Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

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Hospital's observed specific standard practice: A novel measure of variation in care for common inpatient pediatric conditions.

J Hosp Med 2022 Mar 27. Epub 2022 Mar 27.

Section of Hospital Medicine, Department of Pediatrics, Clinical Effectiveness Team, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, USA.

Background: Previously few means existed to broadly examine variability across conditions/practices within or between hospitals for common pediatric conditions.

Objective: Our objective was to develop a novel empiric measure of variation in care and test its association with patient-centered outcomes.

Designs: We conducted a retrospective cohort study of children hospitalized from January 2016 to December 2018 using the Pediatric Hospital Information Systems database. Read More

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Molecular Study of Adenovirus Genotypes 40 and 41 in Children with Acute Gastroenteritis.

Infect Disord Drug Targets 2022 May 9. Epub 2022 May 9.

Department of Clinical Pathology, Mansoura Faculty of Medicine.

Background: Adenovirus is a common virus associated with acute gastroenteritis in children. There are certain genotypes that are prevalent in these infections such as genotypes 40 and 41.

Objective: The aim of the present study was to investigate the incidence of adenovirus genotypes 40 and 41 in children with acute gastroenteritis by polymerase chain reaction (PCR) and also to determine the possibility of Adenovirus co-infections with Rota virus. Read More

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[Application of ultrasound-guided endoscopic retrograde appendicitis therapy in children with appendix-related chronic abdominal pain].

Zhongguo Dang Dai Er Ke Za Zhi 2022 Apr;24(4):360-365

Department of Pediatrics, Tangdu Hospital, Air Force Military Medical University, Shaanxi, Xi'an 710038, China.

Objectives: To study the clinical efficacy of ultrasound-guided endoscopic retrograde appendicitis therapy in children with appendix-related chronic abdominal pain.

Methods: A retrospective analysis was performed on the medical data of 30 children with the chief complaint of chronic abdominal pain who were admitted from August 2019 to May 2021. All the children were found to have inflammation of the appendix or intracavitary stool and fecalith by ultrasound and underwent ultrasound-guided endoscopic retrograde appendicitis therapy. Read More

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Zbtb20 identifies and controls a thymus-derived population of regulatory T cells that play a role in intestinal homeostasis.

Sci Immunol 2022 May 6;7(71):eabf3717. Epub 2022 May 6.

Child Health Institute of New Jersey, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA.

The expression of BTB-ZF transcription factors such as ThPOK in CD4 T cells, Bcl6 in T follicular helper cells, and PLZF in natural killer T cells defines the fundamental nature and characteristics of these cells. Screening for lineage-defining BTB-ZF genes led to the discovery of a subset of T cells that expressed Zbtb20. About half of Zbtb20 T cells expressed FoxP3, the lineage-defining transcription factor for regulatory T cells (T). Read More

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Food protein-induced enterocolitis syndrome caused by scallop.

Pediatr Int 2022 01;64(1):e15202

Department of Pediatrics, KKR Sapporo Medical Center, Sapporo, Japan.

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January 2022

The common triggers of urticaria in children admitted to the pediatric emergency room.

Pediatr Dermatol 2022 May 6. Epub 2022 May 6.

Division of Pediatric Allergy, Hacettepe University School of Medicine, Ankara, Turkey.

Background: Urticaria frequently causes pediatric emergency department (PED) admissions. Children with urticaria may unnecessarily avoid suspected allergens. We aimed to investigate the possible and exact triggers of urticaria in children admitted to the PED. Read More

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Lactobacillus rhamnosus GG Evaluation in Acute Diarrhea (LEAD): An Observational Study.

Cureus 2022 Apr 29;14(4):e24594. Epub 2022 Apr 29.

Clinical Research, ACT Life Sciences Pvt Ltd., Navi Mumbai, IND.

Background and objective Probiotics with documented efficacy such as GG(LGG) and might be utilized as adjuncts to rehydration for the management of acute gastroenteritis (AGE) in children. In this study, we aimed to evaluate the potential role of LGG in acute diarrhea in the Indian pediatric population. Methods An observational, cross-sectional study [ GG Evaluation in Acute Diarrhea (LEAD)] was conducted among children aged one month to 12 years with acute watery diarrhea. Read More

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Epidemiology and Clinical Characteristics of Human Coronaviruses-Associated Infections in Children: A Multi-Center Study.

Front Pediatr 2022 12;10:877759. Epub 2022 Apr 12.

Department of Pediatrics, Pusan National University Children's Hospital, Yangsan, South Korea.

Background: Human coronaviruses (HCoVs) are associated with upper respiratory tract infections. Although studies have analyzed the clinical and epidemiological characteristics of HCoV-associated infections, no multi-center studies have been conducted in Korean children. We aimed to describe the epidemiology and clinical characteristics of HCoV-associated infection in children. Read More

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Severe hip arthritis as an initial presenting symptom of pediatric ulcerative colitis.

Pediatr Int 2022 01;64(1):e15067

Center for Pediatric Inflammatory Bowel Disease, Division of Gastroenterology, National Center for Child Health and Development, Tokyo, Japan.

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January 2022

Pen Foreign Body Ingestion Mimicking Crohn's Disease in a Pediatric Patient.

R I Med J (2013) 2022 May 2;105(4):41-43. Epub 2022 May 2.

Department of Pediatrics, Hasbro Children's Hospital and the Warren Alpert Medical School of Brown University, Providence RI.

Foreign body ingestion is common in pediatrics, particularly in children with psychiatric illness. Foreign bodies present for extended periods of time can trigger a local inflammatory reaction causing weight loss, abdominal pain, and elevated inflammatory markers, mimicking inflammatory bowel disease (IBD). We report a case of intentional pen ingestion in a 13-year-old, whose clinical presentation with elevated inflammatory markers and terminal ileitis suggested on imaging was initially suspicious for Crohn's disease but was found on colonoscopy to be due to foreign body reaction from ingestion of a pen. Read More

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A Mediterranean-like fat blend protects against the development of severe colitis in the mucin-2 deficient murine model.

Gut Microbes 2022 Jan-Dec;14(1):2055441

Department of Biology, University of British Columbia - Okanagan Campus; Kelowna, British Columbia, Canada.

There is a growing appreciation that the interaction between diet, the gut microbiota and the immune system contribute to the development and progression of inflammatory bowel disease (IBD). A mounting body of scientific evidence suggests that high-fat diets exacerbate IBD; however, there is a lack of information on how specific types of fat impact colitis. The Mediterranean diet (MD) is considered a health-promoting diet containing approximately 40% total fat. Read More

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Early diagnosis of egg yolk-associated FPIES relates to early tolerance acquisition.

Pediatr Allergy Immunol 2022 Apr;33(4):e13769

Department of Pediatrics, KKR Sapporo Medical Center, Sapporo, Japan.

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Linking Genetic Diagnosis to Therapeutic Approach in Very Early Onset Inflammatory Bowel Disease: Pharmacologic Considerations.

Paediatr Drugs 2022 May 25;24(3):207-216. Epub 2022 Apr 25.

Division of Gastroenterology, Seattle Children's Hospital Inflammatory Bowel Disease Center, Seattle, WA, USA.

Very early onset inflammatory bowel disease (VEO-IBD) is diagnosed in children < 6 years of age, and in rare cases may be due to an identifiable monogenic cause. Recent advances in genetic testing have allowed for more accurate diagnosis, with as many as 100 genes now known to be associated with monogenic inflammatory bowel disease. These genes are involved in many immune pathways and thus may represent potential avenues for targeted precision medicine with pharmacologic treatments aimed at these. Read More

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Epidemiology, Clinical Features, and Unusual Complications of Norovirus Infection in Taiwan: What We Know after Rotavirus Vaccines.

Pathogens 2022 Apr 9;11(4). Epub 2022 Apr 9.

Department of Pediatrics, School of Medicine, College of Medicine, Taipei Medical University, Taipei city 11031, Taiwan.

Noroviruses (NoVs) are one of the emerging and rapidly spreading groups of pathogens threatening human health. A reduction in sporadic NoV infections was noted following the start of the COVID-19 pandemic, but the return of NoV gastroenteritis during the COVID-19 pandemic has been noted recently. Research in recent years has shown that different virus strains are associated with different clinical characteristics; moreover, there is a paucity of research into extraintestinal or unusual complications that may be associated with NoV. Read More

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Can ultrasound help differentiate between Yersinia enteritis and other bacterial enteritides? A feasible but not easy-to-use diagnostic imaging method.

Yu-Cheng Lin

Pediatr Neonatol 2022 May 9;63(3):209-210. Epub 2022 Apr 9.

Department of Pediatrics, Far Eastern Memorial Hospital, New Taipei City, Taiwan; Department of Healthcare Administration, Asia Eastern University of Science and Technology, New Taipei City, Taiwan. Electronic address:

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The Effect of a Structured Gastroenteritis Discharge Management Plan on Compliance, Prognosis, and Parents' Satisfaction.

Cureus 2022 Mar 16;14(3):e23240. Epub 2022 Mar 16.

Department of Pediatric Emergency, Maternity and Children Hospital, Makkah, SAU.

Background: Acute gastroenteritis is one of the most common causes of dehydration in children. Parents' education is an essential part of its management. In this study, we assessed the efficacy of discharge instructions in the pediatric emergency department for parents of children with acute gastroenteritis, together with disease prognosis and parents' satisfaction. Read More

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Longitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infants.

Nat Microbiol 2022 May 21;7(5):653-662. Epub 2022 Apr 21.

School of Life Sciences, Arizona State University, Tempe, AZ, USA.

Necrotizing enterocolitis (NEC) is a serious consequence of preterm birth and is often associated with gut bacterial microbiome alterations. However, little is known about the development of the gut virome in preterm infants, or its role in NEC. Here, using metagenomic sequencing, we characterized the DNA gut virome of 9 preterm infants who developed NEC and 14 gestational age-matched preterm infants who did not. Read More

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Clinical significance and intestinal microbiota composition in immunocompromised children with norovirus gastroenteritis.

PLoS One 2022 20;17(4):e0266876. Epub 2022 Apr 20.

Division of Pediatric Gastroenterology, Department of Pediatrics, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan.

Background: Norovirus (NoV) infection is common in pediatric patients with immunodeficiency and is more likely to cause severe disease. Objective Our study aims to figure out the clinical differences and distribution of intestinal microbiota in immunocompromised children with NoV gastroenteritis.

Methods: Pediatric patients admitted to Shang-Ho Hospital with diagnosis of acute gastroenteritis including different immune status were enrolled and their medical records were reviewed. Read More

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