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    130 results match your criteria Pediatrics Epiglottitis

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    Clinical characteristics of children and adolescents with croup and epiglottitis who visited 146 Emergency Departments in Korea.
    Korean J Pediatr 2015 Oct 21;58(10):380-5. Epub 2015 Oct 21.
    Department of Pediatrics, National Medical Center, Seoul, Korea.
    Purpose: Croup is a common pediatric respiratory illness with symptoms of varying severity. Moreover, epiglottitis is a rare disease that can rapidly progress to life-threatening airway obstruction. Although the clinical course and treatments differ between croup and epiglottitis, they are difficult to differentiate on presentation. Read More

    Upper Airway Obstruction in Children.
    Indian J Pediatr 2015 Aug 25;82(8):737-44. Epub 2015 Jun 25.
    Division of Pediatric Pulmonology and Intensive Care, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.
    Children with upper airway obstruction are both unique and variable in their presentation and management, often posing a challenge to the pediatrician. Several anatomical and physiologic peculiarities make a child vulnerable to develop an obstruction of upper airways. The characteristic finding in upper airway obstruction is stridor-inspiratory, biphasic or expiratory. Read More

    A Case of Necrotizing Epiglottitis Due to Nontoxigenic Corynebacterium diphtheriae.
    Pediatrics 2015 Jul 8;136(1):e242-5. Epub 2015 Jun 8.
    Infectious Disease, Medical College of Wisconsin, Milwaukee, Wisconsin; and.
    Diphtheria is a rare cause of infection in highly vaccinated populations and may not be recognized by modern clinicians. Infections by nontoxigenic Corynebacterium diphtheriae are emerging. We report the first case of necrotizing epiglottitis secondary to nontoxigenic C diphtheriae. Read More

    Prevalence of antibiotic use for pediatric acute upper respiratory tract infections in Korea.
    J Korean Med Sci 2015 May 15;30(5):617-24. Epub 2015 Apr 15.
    Korea Institute of Drug Safety and Risk Management (KIDS), Seoul, Korea. ; Department of Preventive Medicine, College of Medicine, Seoul National University, Seoul, Korea.
    This study was conducted to estimate the prevalence of antimicrobial prescribing for acute upper respiratory tract infections (URI) among pediatric outpatients and to identify the national patterns of its use from 2009 to 2011 in Korea. Using National Patients Sample database from 2009 to 2011, we estimated the frequency of antibiotics prescribing for URI in pediatric outpatients with diagnoses of acute nasopharyngitis (common cold), acute sinusitis, acute pharyngitis, acute tonsillitis, acute laryngitis/tracheitis, acute obstructive laryngitis/epiglottitis, and acute upper respiratory infections of multiple and unspecified sites. The proportions of each antibiotic class were calculated by year and absolute and relative differences were estimated. Read More

    Aphonia and epiglottitis in neonate with concomitant MRSA skin infection.
    Respirol Case Rep 2014 Sep 25;2(3):116-9. Epub 2014 Aug 25.
    Department of Pediatrics, University of Toledo Toledo, Ohio, United States of America.
    We report an unusual case of a neonate with aphonia due to epiglottitis with a concomitant methicillin-resistant S taphylococcus aureus (MRSA) infection of the genitalia and associated septic emboli to the groin area and mouth. We postulate that the MRSA infection caused a transient bacteremia that seeded the epiglottis, likely causing the epiglottitis. In the evaluation of a neonate with aphonia, while the two primary differentials to consider are vocal cord paralysis and laryngeal web, among other considerations is epiglottitis (supraglottitis). Read More

    [Acute epiglottitis due to group A β-hemolytic streptococcus in a child].
    Arch Pediatr 2015 Jun 2;22(6):613-5. Epub 2014 Oct 2.
    Service de médecine infantile, hôpital Nord, chemin des Bourrely, 13915 Marseille cedex 20, France.
    Acute epiglottitis has become an exceptional observation in pediatrics. The introduction of Haemophilus influenzae type B vaccine changed the morbidity, mortality, and microbiology of this disease. We report the case of an 11-month-old infant with acute epiglottitis due to group A β-hemolytic streptococcus. Read More

    Epiglottitis as a presentation of leukemia in an adolescent.
    Pediatr Emerg Care 2014 Oct;30(10):733-5
    From the *Department of Medicine, University of Toronto, Toronto, Canada; †Department of Pediatrics, Albert Einstein University, New York, NY; ‡Pediatric Emergency Medicine, St. Barnabas Hospital, Bronx, NY; §Division of Pediatric Otolaryngology-Head and Neck Surgery, B.C. Children's Hospital; and ∥Division of Pediatric Emergency Medicine, Department of Pediatrics, Wilson Centre for Research In Education, Centre for Faculty Development, Hospital for Sick Children, University of Toronto, Toronto, Canada.
    Epiglottitis is a life-threatening entity that can present in children or adults. Although the incidence has declined since the introduction of the Haemophilus influenzae type B vaccine in 1985, cases continue to be identified in high-risk populations. In pediatric oncology patients specifically, epiglottitis has been reported after initiation of chemotherapy. Read More

    BMJ Clin Evid 2014 Sep 29;2014. Epub 2014 Sep 29.
    Department of Pediatrics, University of Calgary, Calgary, Canada.
    Introduction: Croup is characterised by the abrupt onset, most commonly at night, of a barking cough, inspiratory stridor, hoarseness, and respiratory distress due to upper airway obstruction. It leads to signs of upper airway obstruction, and must be differentiated from acute epiglottitis, bacterial tracheitis, or an inhaled foreign body. Croup affects about 3% of children per year, usually between the ages of 6 months and 3 years, and 75% of infections are caused by parainfluenza virus. Read More

    Update on pediatric neurocritical care.
    Paediatr Anaesth 2014 Jul 2;24(7):717-23. Epub 2014 Apr 2.
    Departments of Neurology and Anesthesiology, Perioperative and Pain Medicine, Division of Critical Care Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
    Paralytic poliomyelitis, Reye syndrome, Hemophilus Influenzae type B epiglottitis, bacterial meningitis, and meningococcal septic shock are catastrophic illnesses that in the last 60 years have shaped the development of pediatric intensive care. Neurocritical care has been at the forefront of our thinking and, more latterly, as a specialty we have had the technology and means to develop this focus, educate the next generation and show that outcomes can be improved-first in adult critical care and now the task is to translate these benefits to critically ill children. In our future we will need to advance interventions in patient care with clinical trials. Read More

    The heat is on... thermal epiglottitis as a late presentation of airway steam injury.
    J Emerg Med 2014 Feb 7;46(2):e43-6. Epub 2013 Oct 7.
    Division of Pediatric Otolaryngology, Department of Otolaryngology and Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland.
    Background: Thermal epiglottitis is a rare but potentially life-threatening disease. Diagnosis requires a thorough history and high clinical level of suspicion, particularly in children. Thermal epiglottitis from steam inhalation can have a slow onset without oropharyngeal signs of thermal injury, findings that can hide the clinical diagnosis. Read More

    The burden of epiglottitis among Japanese children before the Haemophilus influenzae type b vaccination era: an analysis using a nationwide administrative database.
    J Infect Chemother 2013 Oct 20;19(5):876-9. Epub 2013 Mar 20.
    Department of Pediatrics, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan,
    Epiglottitis is a potentially life-threatening disease and is largely preventable by vaccination against Haemophilus influenzae type b (Hib). Little is known, however, about the epidemiology of childhood epiglottitis in Asian countries, including Japan. Using a nationwide inpatient database, this study aimed to determine the burden of childhood epiglottitis before the introduction of Hib vaccine into Japan. Read More

    Office immunization.
    Prim Care 2011 Dec 17;38(4):729-45, ix. Epub 2011 Sep 17.
    Department of Pediatrics, Thomas Jefferson University, 833 Chestnut Street, Suite 300, Philadelphia, PA 19107, USA.
    Nothing has improved disease control as thoroughly as immunizations. In well-immunized populations, there is no flaccid paralysis (polio), almost no epiglottitis or postmeningitis deafness (Haemophilus influenzae), and little postviral male sterility (mumps). Immunizations are not perfect; they may cause side effects, some of which have led to the discontinuation of the vaccine when side effects have outweighed the vaccine's protective effects. Read More

    [Antibiotic susceptibility to parental antibiotics and penicillin-binding-protein genotype in Haemophilus influenzae isolated from children with invasive infection].
    Kansenshogaku Zasshi 2011 Jan;85(1):26-30
    Department of Pediatrics, Asahikawa Kosei Hospital.
    The minimum inhibitory concentation (MIC) and minimum bactericidal concentration (MBC) of 8 parental antibiotics were determined using 21 strains of Haemophilus influenzae from 21 children with invasive H. influenzae infection in 2006-2009. Children were from 4 months to 12 years, with 18 (85. Read More

    Symptoms and signs differentiating croup and epiglottitis.
    J Paediatr Child Health 2011 Mar 21;47(3):77-82. Epub 2010 Nov 21.
    Intensive Care Unit and Department of Paediatrics, Royal Children's Hospital Melbourne, The University of Melbourne, Melbourne, Victoria, Australia.
    Aim: To determine differentiating symptoms and signs of epiglottitis and laryngotracheobronchitis (croup).

    Methods: Contemporaneous interview of parents and clinical examination of children with acute upper airway obstruction presenting to the intensive care unit of a paediatric hospital.

    Results: Two hundred and three children were examined over a 40-month period. Read More

    Association between single-nucleotide polymorphisms in Mal/TIRAP and interleukin-10 genes and susceptibility to invasive haemophilus influenzae serotype b infection in immunized children.
    Clin Infect Dis 2010 Oct;51(7):761-7
    Academic Unit of Paediatrics, Barts and The London School of Medicine and Dentistry, London, United Kingdom.
    Background: The development of invasive Haemophilus influenzae serotype b (Hib) disease after prior immunization with the Hib conjugate vaccine (ie, Hib vaccine failure) is extremely rare, suggesting that affected children may have an underlying genetic susceptibility in their immune response. The objective of this study was to investigate single-nucleotide polymorphisms (SNPs) known to affect function in biologically plausible genes in relation to the risk of Hib vaccine failure and its clinical manifestations.

    Methods: The families of UK children with Hib vaccine failure diagnosed during the period October 1992 through December 2005 were identified through enhanced national surveillance and approached for the study at a median interval of 4 years after invasive disease. Read More

    BMJ Clin Evid 2009 Mar 10;2009. Epub 2009 Mar 10.
    Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.
    Introduction: Croup leads to signs of upper airway obstruction, and must be differentiated from acute epiglottitis, bacterial tracheitis, or an inhaled foreign body. Croup affects about 3% of children a year, usually between the ages of 6 months and 3 years, and 75% of infections are caused by Parainfluenza virus. Symptoms usually resolve within 48 hours, but severe infection can, rarely, lead to pneumonia, and to respiratory failure and arrest. Read More

    Tracheostomy in young patients: indications and long-term outcome.
    Eur Arch Otorhinolaryngol 2009 May 3;266(5):705-11. Epub 2008 Sep 3.
    Department of Otorhinolaryngology Head and Neck Surgery, Friederich Alexander University of Erlangen-Nuremberg, Waldstr. 1, 91054, Erlangen, Germany.
    Diagnostic and treatment modalities have changed substantially over the past years in the field of pediatrics and neonatal medicine. As a result, the indications and outcome after tracheostomy in young patients have evolved. The aim of this study is to present our experience with pediatric tracheostomies and provide an up-to-date review of the literature with special focus on current trends. Read More

    An infant with fever and stridor.
    Pediatr Emerg Care 2008 Jan;24(1):46-9
    Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229-3039, USA.
    The clinical spectrum of infectious causes of upper airway obstruction has changed dramatically in the last few decades, especially after the introduction of vaccines against diphtheria and Haemophilus influenzae. Nevertheless, infectious causes of upper airway obstruction remain an important source of morbidity and potential mortality in the pediatric age group. Physicians caring for children need to be cognizant of the clinical presentation of this group of disorders because prompt recognition and early appropriate treatment are lifesaving. Read More

    Pediatric respiratory infections.
    Emerg Med Clin North Am 2007 Nov;25(4):961-79, vi
    Division of Emergency Medicine, Rady Children's Hospital, University of California-San Diego, 3020 Children's Way, San Diego, CA 92123, USA.
    Pediatric respiratory infections are a common presenting complaint to the emergency department. This article discusses the presentation and management of infectious conditions, including bacterial tracheitis, bronchiolitis, croup, epiglottitis, pertussis, pneumonia, and retropharyngeal abscess. Read More

    Invasive Haemophilus influenzae infections in children in Kamikawa subprefecture, Hokkaido, Japan, 1996-2005, before the introduction of H. influenzae type b vaccination.
    J Infect Chemother 2007 Feb 26;13(1):30-4. Epub 2007 Feb 26.
    Department of Pediatrics, Asahikawa Kosei Hospital, 1-24 Asahikawa, Hokkaido 078-8211, Japan.
    We evaluated 52 children with invasive Haemophilus influenzae infection in Kamikawa subprefucture, Hokkaido, Japan between 1996 and 2005. The most frequent disease was meningitis, in 30 children (57.7%), followed by pneumonia in 9 (17. Read More

    Changing epidemiology of life-threatening upper airway infections: the reemergence of bacterial tracheitis.
    Pediatrics 2006 Oct;118(4):1418-21
    Division of Pediatric Critical Care Medicine, Department of Pediatrics, University of Colorado School of Medicine, Denver, Colorado, USA.
    Objective: As a consequence of evolving medical practice, the epidemiology of potentially life-threatening upper airway infections is changing. We report our experience over 9 years with viral croup, epiglottitis, and bacterial tracheitis.

    Patients And Methods: We studied a retrospective case series of patients admitted to Vermont Children's Hospital with potentially life-threatening upper airway infections viral croup, epiglottitis, or bacterial tracheitis between 1997 and 2006. Read More

    The dramatic change in the epidemiology of pediatric epiglottitis.
    Pediatr Emerg Care 2006 Jun;22(6):443-4
    Department of Pediatrics, School of Medicine and Biomedical Sciences, State University of New York at Buffalo, and Division of Infectious Diseases, Women and Children's Hospital of Buffalo, Buffalo, NY 14222, USA.
    Objective: To review the epidemiology of epiglottitis in a large children's hospital from 1995-2003 and to compare the findings with a previous report published 27 years previously from the same hospital.

    Methods: Chart review.

    Results: Two cases identified. Read More

    Use of antimicrobial agents for upper respiratory tract infections in Taiwanese children.
    Chang Gung Med J 2005 Nov;28(11):758-64
    Division of Pediatric Pulmonology, Department of Pediatrics, Chang Gung Children's Hospital, Taipei.
    Upper respiratory tract infections (URTIs) are mostly caused by viruses. Antibiotic misuse for viral URTIs in children is a serious problem that not only results in selection of resistant strains of bacteria but also wastes millions of dollars each year in Taiwan. Antibiotic resistance among common respiratory bacterial pathogens such as Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, and Moraxella catarrhalis has become a major issue for public health. Read More

    Hereditary angioedema presenting as epiglottitis.
    Pediatr Emerg Care 2005 Jan;21(1):27-30
    Emergency Medicine and Pediatrics, Virginia Commonwealth, University Health System, Richmond, VA 23298-0401, USA.
    Hereditary angioedema is a disorder characterized by decreased levels or function of complement C1 esterase inhibitor. Symptoms in children generally consist of recurrent episodes of soft tissue swelling. On rare occasion, it can cause airway edema which may lead to airway obstruction. Read More

    Acute epiglottitis caused by Haemophilus influenzae type b: a case report.
    J Microbiol Immunol Infect 2003 Mar;36(1):69-71
    Department of Pediatrics, Mackay Memorial Hospital, Taipei, Taiwan, ROC.
    Acute epiglottitis is an inflammatory, edematous disease of the epiglottis and adjacent structures, usually caused by Haemophilus influenzae type b. It is a life-threatening condition, occurring mainly in childhood. There have never been any reports of this condition in Taiwan. Read More

    Immunologic memory in Haemophilus influenzae type b conjugate vaccine failure.
    Arch Dis Child 2003 May;88(5):379-83
    Oxford Vaccine Group, University of Oxford Department of Paediatrics, John Radcliffe Hospital, Oxford, UK.
    Aims: To compare the convalescent antibody response to invasive Haemophilus influenzae type b (Hib) disease between conjugate vaccine immunised and unimmunised children, to look for evidence of priming for immunologic memory.

    Methods: Unmatched case-control study in the UK and Eire 1992-2001 and Victoria, Australia 1988-1990. A total of 93 children were identified as having invasive Hib disease following three doses of conjugate vaccine in infancy through post licensure surveillance throughout the UK and Eire; 92 unvaccinated children admitted to an Australian paediatric hospital with invasive Hib disease were used as historical controls. Read More

    Respiratory emergencies in children.
    Respir Care 2003 Mar;48(3):248-58; discussion 258-60
    Division of Pediatric Critical Care Medicine, The Children's Hospital of Buffalo, Buffalo, New York 14222, USA.
    Acute obstructive respiratory emergencies in children are a common cause of emergency department visits. The severity of these conditions ranges from mild, self-limited disease to life-threatening forms of rapidly progressive airway obstruction. A high index of suspicion is necessary for prompt diagnosis and treatment. Read More

    Current trends in neonatal and pediatric respiratory care: conference summary.
    Respir Care 2003 Apr;48(4):459-64
    Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, OH 44106, USA.
    A summary of the 2-day Journal Conference on Current Trends in Neonatal and Pediatric Respiratory Care is provided. Topics included: diagnosis and management of common respiratory disorders of infants and children such as asthma, respiratory syncytial virus bronchiolitis, and cystic fibrosis; and common pediatric respiratory emergencies such as croup, epiglottitis, and inhalation injuries. Also discussed were developments in diagnostic and therapeutic modalities, including pulmonary function testing and pulse oximetry. Read More

    Signature Tagged Mutagenesis of Haemophilus influenzae identifies genes required for in vivo survival.
    Microb Pathog 2002 Nov;33(5):211-23
    Molecular Infectious Diseases Group, Department of Paediatrics, The Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, OX3 9DU, UK.
    The pathogenic bacterium Haemophilus influenzae causes meningitis, epiglottitis, pneumonia, otitis media and other infections. To further understand the genetic basis of invasive disease and to inform about the bacterium's requirements in an in vivo environment, we analysed a library of 1632 insertional Tn1545 -Delta3 transposon mutants for their capacity to cause systemic infection in an animal model. We identified 25 genes that are potentially essential for H. Read More

    Life threatening acute epiglottitis in acute leukemia.
    Leuk Lymphoma 2002 Mar;43(3):665-7
    Department of Paediatrics, Tuen Mun Hospital, New Territories, Hong Kong, China.
    We report an 8-year-old boy who developed a life-threatening acute epiglottitis during induction chemotherapy for acute promyelocytic leukemia. He survived the infection with emergency tracheostomy, treatment with broad spectrum antibiotics and amphotericin, and the use of granulocyte-macrophage colony stimulating factor. No organism was identified. Read More

    Emergency department management of acute respiratory infections.
    Semin Respir Infect 2002 Mar;17(1):65-71
    Department of Pediatrics, Section of Emergency Medicine, Baylor College of Medicine, Houston, TX, USA.
    Respiratory tract infections are one of the most common problems prompting visits to the emergency department. Although many are the result of self-limited viral illnesses, these infections may result in substantial morbidity and, rarely, mortality. Prompt recognition and appropriate treatment can reduce morbidity and largely prevent mortality. Read More

    Update on pneumococcal infections of the respiratory tract.
    Semin Respir Infect 2002 Mar;17(1):3-9
    Department of Pediatrics, Northwestern University Medical School, Chicago, IL 60614, USA.
    Respiratory illnesses are the leading reason for seeking medical care here in the United States. Streptococcus pneumoniae is the most common bacterial pathogen causing acute otitis media (AOM), sinusitis, and community-acquired pneumonia in both the pediatric and adult populations. The continued development of antibiotic resistance to an increasing number of different antibiotic classes by this organism has made the treatment of some of these infections more difficult. Read More

    Pediatric otolaryngologic emergencies.
    Anesthesiol Clin North America 2001 Jun;19(2):237-56, vi
    Departments of Anesthesiology and Pediatrics, George Washington University Medical Center, USA.
    Anesthesiologists are often consulted to help in the management of pediatric otolaryngologic emergencies. These include airway obstruction in children suffering from acute epiglottitis and croup. Surgical otolaryngologic emergencies such as foreign body aspiration, post-tonsillectomy bleeding, obstructive laryngeal papillomatosis, peritonsillar abscess, and laryngeal trauma can be life threatening. Read More

    Retropharyngeal abscess: epiglottitis of the new millennium.
    J Pediatr 2001 Mar;138(3):435-7
    Department of Pediatrics, Inova Fairfax Hospital for Children, Falls Church, Virginia, USA.
    From 1993 through 1999, 26 children with retropharyngeal abscess and 2 children with acute epiglottitis were cared for by pediatric otolaryngologists in northern Virginia. Fever, sore throat, dysphagia, refusal to swallow, dysphonia, drooling, and neck extension are common presenting signs and symptoms in acute epiglottitis and in retropharyngeal abscess. Contrast-enhanced computed tomography of the oropharynx was performed in all cases and was the most helpful diagnostic test. Read More

    Severe upper airway obstruction in the tropics requiring intensive care.
    Pediatr Int 2001 Feb;43(1):53-7
    Department of Pediatrics, University Malaya Medical Center, Kuala Lumpur, Malaysia.
    Background: The clinical profile of severe upper airway obstruction, a challenging acute pediatric emergency, has not been extensively documented in the developing nations of the tropics.

    Methods: The diagnostic categories, severity of illness and outcome from 63 episodes of severe upper airway obstruction in 56 children admitted to the Pediatric Intensive Care Unit between January 1994 and December 1999 were reviewed. Outcome variables studied included requirement for ventilation, mortality and complications. Read More

    Pediatric airway issues.
    Crit Care Clin 2000 Jul;16(3):489-504
    Department of Pediatric Critical Care Medicine, Children's Hospital of Philadelphia, Pennsylvania, USA.
    Airway management in the pediatric patient requires an understanding and knowledge of the differences and characteristics unique to the child and infant. New and exciting techniques are currently being explored and developed for management of the pediatric airway. Technology in the area of imaging has allowed clinicians to better visualize the airway and aberrations of it. Read More

    Croup syndrome in children: five-year experience.
    Acta Paediatr Taiwan 1999 Jul-Aug;40(4):258-61
    Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan.
    To investigate the etiology and clinical features of croup syndrome, clinical records of hospitalized children with a diagnosis of croup syndrome were reviewed from April 1990 to January 1996. There was a total of 132 children, aged between three months and seven years with a mean age of 21.3 +/- 16. Read More

    Invasive Haemophilus influenzae type b infections in Singapore children: a hospital-based study.
    J Paediatr Child Health 2000 Apr;36(2):125-7
    Department of Paediatrics and Division of Microbiology, Department of Laboratory Medicine, National University Hospital, Singapore.
    Objective: A 6-year (1990-95) hospital-based retrospective study was carried out to investigate the pattern of invasive Haemophilus influenzae type b (Hib) disease.

    Methodology: Cases with Hib isolated from sterile sites (blood, cerebrospinal fluid, or joint aspirate) were identified from the hospital's microbiological records, and their reviewed case records. Patients with pyogenic meningitis in the same study period were also identified to estimate the incidence of Hib meningitis. Read More

    Post-varicella epiglottitis and necrotizing fasciitis.
    Pediatrics 2000 Jan;105(1):e13
    Department of Otolaryngology, University of Colorado School of Medicine, Children's Hospital, Denver, Colorado, USA.
    Varicella is a nearly ubiquitous acquired childhood disease. Infectious complications of varicella can be life- or limb-threatening. These complications appear 3 to 4 days after the appearance of varicella exanthem and are heralded by fever, pain, and erythema of the overlying skin. Read More

    Epidemiology of systemic Haemophilus influenzae disease in Korean children.
    Pediatr Infect Dis J 1998 Sep;17(9 Suppl):S185-9
    Department of Pediatrics, Seoul National University College of Medicine, Korea.
    Background: There is a wide variation in the incidence and clinical characteristics of invasive infections by Haemophilus influenzae type b (Hib) among different populations. Characterizing the clinical significance in a particular community is essential for the development of vaccine policy. Data on the clinical significance of Hib in Asian children, including epidemiology and clinical spectrum, are quite limited. Read More

    Aetiology of acute epiglottitis in adults.
    Scand J Infect Dis 1998 ;30(1):49-51
    Department of Paediatrics, Sahlgrenska Hospital, Göteborg, Sweden.
    In order to determine the aetiology of acute epiglottitis in adults, blood cultures, paired sera and a urine sample were obtained from 54 patients with fever and epiglottitis visualized by indirect laryngoscopy or by direct fibreoptic nasolaryngoscopy. Antibodies were determined against the capsular polysaccharide of Haemophilus influenzae type b (Hib), 3 pneumococcal antigens (a mixture of 23 capsular polysaccharides, C-polysaccharide and pneumolysin) and antistreptolysin O. Acute sera were examined by the polymerase chain reaction (PCR) for DNA of Hib and pneumococci. Read More

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