J Investig Allergol Clin Immunol 2017 ;27(1):1-18
Unidade de Alergia e Imunologia do Instituto da Criança, HC Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-, cell-mediated food allergy of unknown prevalence and pathophysiology. Onset is typically during the first year of life; seafood-induced FPIES may start in adulthood. Acute FPIES manifests within 1-4 hours after ingestion with repetitive emesis, pallor, and lethargy progressing to dehydration and hypovolemic shock in 15% of cases. Read More