19,982 results match your criteria Pediatrics Chicken Pox or Varicella

A Case Report of Herpes Zoster Ophthalmicus and Meningitis After COVID-19 Vaccination.

J Korean Med Sci 2022 May 23;37(20):e165. Epub 2022 May 23.

Department of Ophthalmology, Jeonbuk National University Medical School, Research Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea.

There are several reports that herpes zoster characterized by reactivation of varicella zoster virus (VZV) following coronavirus disease 2019 (COVID-19) vaccines can occur. Herein, we report VZV meningitis, herpes zoster ophthalmicus (HZO), and late neurotrophic keratitis after receiving a second dose of messenger RNA (mRNA) COVID-19 vaccine. A 74-year-old man developed a vesicular skin rash on the forehead, scalp, nose, and left upper eyelid with a severe headache. Read More

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Erythema multiforme in a young adult following COVID-19 infection and vaccination in Tanzania.

BMJ Case Rep 2022 May 23;15(5). Epub 2022 May 23.

Haematology, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.

We report the case of a young female adult in her early 20s, who had COVID-19 infection for 8 weeks and COVID-19 vaccination 4 weeks prior to presentation with an extensive rash associated with erythema multiforme, resembling varicella zoster on initial presentation. After initial acyclovir therapy with no improvement, systemic corticosteroid treatment dramatically resolved the patient's skin rash. Read More

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Case 302: Supratentorial Lymphocytic Inflammation with Parenchymal Perivascular Enhancement Responsive to Steroids.

Radiology 2022 Jun;303(3):726-730

From the Department of Radiology, Neuroradiology Section, University of Arkansas for Medical Sciences, Little Rock, Ark (S.V.); Department of Clinical Imaging, Hamad General Hospital (L.A.), and Department of Neuroradiology, Neuroscience Institute (M.A., A.H.E.B.), Hamad Medical, PO Box 3050, Alsadd, Doha, Qatar; and Department of Clinical Radiology, Weill Cornell Medicine, Doha, Qatar (A.H.E.B.).

History: Part one of this case appeared 4 months previously and may contain larger images. A 21-year-old immunocompetent man who was a long-term resident of Qatar presented to the emergency department with recurrent episodes of unprovoked generalized tonic-clonic seizures lasting 2-3 minutes that spontaneously resolved and were associated with postictal confusion. The patient also had progressive mild diplopia, intermittent dizziness, and numbness in the left arm over the course of 3 months. Read More

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Atypical anti-NMDA receptor encephalitis associated with varicella zoster virus infection.

J Neurovirol 2022 May 23. Epub 2022 May 23.

Neurology Department, Mongi Ben Hamida Institute of Neurology, University of Tunis El Manar, Omar Chedly Street 1029, Bab Saâdoun, Tunis, Tunisia.

The triggering effect of herpes simplex virus infection on the development of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is now well established. However, there are very few reports that has linked a varicella zoster virus (VZV) reactivation with anti-NMDAR encephalitis. In this report, we describe a case of a 57-year-old man presented with atypical clinical presentation of anti-NMDAR encephalitis with gait ataxia, complete ophtalmoplegia, and abolished reflexes followed by drowsiness and confusion. Read More

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Transmission dynamics of varicella before, during and after the COVID-19 pandemic in Japan: a modelling study.

Math Biosci Eng 2022 Apr;19(6):5998-6012

School of Public Health, Kyoto University, Kyoto, Japan.

Public health and social measures (PHSMs) targeting the coronavirus disease 2019 (COVID-19) pandemic have potentially affected the epidemiological dynamics of endemic infectious diseases. In this study, we investigated the impact of PHSMs for COVID-19, with a particular focus on varicella dynamics in Japan. We adopted the susceptible-infectious-recovered type of mathematical model to reconstruct the epidemiological dynamics of varicella from Jan. Read More

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Effect of COVID-19 restrictions and border closures on vaccine preventable diseases in Victoria, Australia, 2020-2021.

Commun Dis Intell (2018) 2022 May 19;46. Epub 2022 May 19.

Department of Health, Victoria, Australia.

Background: In 2020, Victoria introduced multiple interventions aimed at containing the spread of coronavirus disease 2019 (COVID-19). We examine the effect of these restrictions on other vaccine preventable diseases (VPDs).

Methods: We analysed the mandatory reporting data, notified to the Victorian Department of Health, for VPDs from January 2015 to December 2021. Read More

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Tetanus seroprotection among children in the Democratic Republic of the Congo, 2013-2014.

PLoS One 2022 19;17(5):e0268703. Epub 2022 May 19.

Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, California, United States of America.

Background: Tetanus is a potentially fatal disease that is preventable through vaccination. While the Democratic Republic of the Congo (DRC) has continued to improve implementing routine vaccination activities throughout the country, they have struggled to maintain high childhood vaccine coverage. This study aims to examine the seroprevalence of tetanus in children 6 to 59 months to identify areas for intervention and improvement of vaccination coverage. Read More

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The measles, mumps, rubella, varicella vaccination was safe in children with acute egg food protein-induced enterocolitis syndrome but anxiety was high.

Acta Paediatr 2022 May 17. Epub 2022 May 17.

Department of Life Sciences and Public Health, Pediatric Allergy Unit, Pediatrics Section, Policlinico Gemelli Universitary Foundation IRCCS, Catholic University of Sacre Hearth, Rome, Italy.

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Low post-transplant measles and varicella titers among pediatric liver transplant recipients: A 10-year single-center study.

Pediatr Transplant 2022 May 17:e14322. Epub 2022 May 17.

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Mattel Children's Hospital at UCLA Medical Center, Los Angeles, California, USA.

Background: Vaccine preventable illnesses are important sources of morbidity, mortality, and increased healthcare costs in pediatric LT recipients. Our aim was to measure the seroprevalence of antibodies to measles and VZV in this population.

Methods: We conducted a retrospective chart review of 44 patients who received LT before age 18 at UCLA Mattel Children's Hospital from January 2008 to December 2017. Read More

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Immunodeficiency Should Be Excluded in Patients With Recurrent Viral Meningitis and Breakthrough COVID-19.

Josef Finsterer

J Korean Med Sci 2022 05 16;37(19):e161. Epub 2022 May 16.

Neurology & Neurophysiology Center, Vienna, Austria.

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Response to a letter to the editor regarding ' the comparison of seroconversion rates among different varicella vaccines administered Turkish children; MAV/06 and vOka'.

Hum Vaccin Immunother 2022 May 16:2073760. Epub 2022 May 16.

Division of Infectious Disease, Department of Pediatrics, Medical School of Ege University, Izmir, Turkey.

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[Clinical and therapeutic features of herpes zoster oticus: a case report].

Pan Afr Med J 2022 3;41:171. Epub 2022 Mar 3.

Service d'Otorhinolaryngologie et de Chirurgie Cervico-Faciale de l'Hôpital Militaire d'Instruction Mohamed V de Rabat, Faculté de Médecine et Pharmacie Rabat, Université Mohamed V Rabat, Rabat, Maroc.

Ear shingles, also called herpes zoster oticus, are a viral infection of the outer, middle and/or inner ear due to varicella zoster virus (VZV). Patients with ear involvement associated with facial palsy are clinically diagnosed with Ramsay-Hunt´s syndrome. We here report the case of a 25-year-old patient with herpes zoster oticus associated with peripheral facial palsy, without other associated signs. Read More

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Development of an Indirect ELISA Kit for Rapid Detection of Varicella-Zoster Virus Antibody by Glycoprotein E.

Front Microbiol 2022 27;13:897752. Epub 2022 Apr 27.

School of Life Sciences, Zhengzhou University, Zhengzhou, China.

Varicella-zoster virus (VZV), a highly infectious agent that causes varicella (chickenpox), can also cause zoster (shingles), a disorder that is frequently associated with severe neuralgia. A reliable serological VZV diagnostic assay would be useful for identifying unprotected individuals and for surveilling post-vaccination immunoprotection status. Toward this goal, VZV membrane glycoprotein E (gE), the immunodominant VZV protein, served as target antigen in an indirect ELISA kit developed here to detect anti-VZV antibodies in clinical samples. Read More

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MR Features of varicella zoster myelitis in an immunocompetent patient.

Curr Med Imaging 2022 May 13. Epub 2022 May 13.

Department of Radiology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey.

Background: Varicella zoster virus [VZV] is a latent virus that can remain in the central nervous system. Reactivation of the virus can cause some neurologic manifestations, and myelitis is one of the rarest of them. In this report, we aimed to present the MRI features of long-segment cervical myelitis after VZV infection, which is rarely reported in the literature. Read More

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Recovery of intracranial stenoses in varicella zoster virus vasculitis after long-term treatment with valacyclovir and prednisolone.

Neurol Res Pract 2022 May 16;4(1):18. Epub 2022 May 16.

German Society of Neurology, Berlin, Germany.

Background And Purpose: Optimal treatment of intracranial stenoses in varicella zoster virus (VZV)-associated vasculitis is unknown. This study aims to evaluate the merits and potential pitfalls of a specific therapeutic strategy, initially proposed by Don Gilden in 2015.

Methods: We describe three patients with intracranial stenoses caused by VZV vasculitis successfully treated by a long-term combination of valacyclovir and prednisolone. Read More

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Catch-up vaccination campaign in children between 6 and 8 years old during COVID-19 pandemic: The experience in a COVID hub in Milan, Italy.

Vaccine 2022 May 12. Epub 2022 May 12.

Dept. Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy; IRCCS Fondazione Ca' Granda - Ospedale Maggiore Policlinico, 20122 Milan, Italy. Electronic address:

Background: COVID-19 has led to disruption in routine immunization programs around the world. Effective strategies need to be developed to address the decline in vaccine coverage to avoid preventable disease outbreaks. Our study reports a 4-days campaign for the catching-up of missed vaccinations in children aged between 6 and 8 years, in Milan, Italy. Read More

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Fragment Size-Based Enrichment of Viral Sequences in Plasma Cell-Free DNA.

J Mol Diagn 2022 May 22;24(5):476-484. Epub 2022 Feb 22.

Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, Washington; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington. Electronic address:

Sequencing of plasma cell-free DNA (cfDNA) is a promising milieu for broad-based cancer and infectious disease diagnostics. The performance of cfDNA sequencing for infectious disease diagnostics is chiefly limited by inadequate analytical sensitivity. The current study investigated whether the analytical sensitivity of cfDNA sequencing for viral diagnostics could be improved by selective sequencing of short cfDNA fragments, given prior observations of shorter fragment size distribution in microbial and cytomegalovirus-derived cfDNA compared with human-derived cfDNA. Read More

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Development of a perfusion process for serum-free adenovirus vector herpes zoster vaccine production.

AMB Express 2022 May 14;12(1):58. Epub 2022 May 14.

Institute of Microbial Engineering, School of Life Sciences, Henan University, Kaifeng, 475004, China.

Herpes zoster is caused by reactivation of the varicella zoster virus (VZV). Researching and developing a herpes zoster vaccine will help to decrease the incidence of herpes zoster. To increase the bioreactor productivity, a serum-free HEK293 cell perfusion process with adenovirus vector herpes zoster (rAd-HZ) vaccine production was developed efficiently using the design of experiment (DoE) method. Read More

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Research Trends and Hotspots on Herpes Zoster: A 10-Year Bibliometric Analysis (2012-2021).

Front Med (Lausanne) 2022 26;9:850762. Epub 2022 Apr 26.

NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Jiangsu Province Key Laboratory of Anesthesiology, Jiangsu Province Key laboratory of Anesthesia and Analgesia, Xuzhou Medical University, Xuzhou, China.

Purpose: Herpes zoster infection, with its considerable burden to individuals and society, remains a challenge around the world. However, to the knowledge of the authors, little bibliometric quantitative or qualitative analysis has been carried out to evaluate herpes zoster research. This study aimed to use a bibliometric analysis to evaluate current publication trends and hotspots on herpes zoster research worldwide, in order to advance research in this field. Read More

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Postinfectious Acute Cerebellar Syndromes in Children: A Nationally Ascertained Case Series From Australia 2013-2018.

J Child Neurol 2022 May 12:8830738221093209. Epub 2022 May 12.

Department of Infectious Diseases & Microbiology, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.

Introduction: Postinfectious acute cerebellar syndromes show a wide spectrum of acute severity and can occur with acute febrile illness or vaccine receipt. Varicella has historically been the most common cause, associated with up to 25% of cases in large cohorts. This study aimed to describe the spectrum of syndromes in a setting with high varicella vaccine coverage. Read More

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Post-varicella arterial ischemic stroke in children and neurocognitive performance: a 4-year follow-up study.

Einstein (Sao Paulo) 2022 6;20:eAO6360. Epub 2022 May 6.

Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.

Objective: To analyze data from children who were previously healthy and presented with post-varicella arterial ischemic stroke upon arrival when admitted to the emergency room, with focus on the clinical/laboratory aspects, and neurocognitive performance after four-year follow-up.

Methods: Seven children presenting with arterial ischemic stroke after varicella were evaluated at pediatric emergency services in the city of São Paulo (SP), Brazil. Ischemic stroke was determined by magnetic resonance imaging/magnetic resonance angiography in a topography compatible with the areas supplied by the middle cerebral or internal carotid arteries. Read More

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Childhood vaccination coverage of hepatitis A, measles, mumps and rubella, and varicella: temporal trend analysis in Minas Gerais, Brazil.

Rev Bras Epidemiol 2022 6;25:e220010. Epub 2022 May 6.

Universidade Federal de São João del Rei - Divinópolis (MG), Brasil.

Objective: To analyze the temporal trend of vaccination coverage for hepatitis A, measles, mumps and rubella, and varicella in a Brazilian state from 2014 to 2020.

Methods: An ecological, time-series study that considered data from 853 municipalities in the state of Minas Gerais that compose the 14 regions of the state, these being the territorial units of analysis. Records of applied doses of hepatitis A, measles, mumps and rubella, and varicella vaccines registered in the Brazilian Immunization Information System were analyzed. Read More

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Epidemiological characteristics of varicella outbreaks in the Republic of Korea, 2016-2020.

Osong Public Health Res Perspect 2022 Apr 26;13(2):133-141. Epub 2022 Apr 26.

Gyeongnam Regional Center for Disease Control and Prevention, Busan, Korea.

Objectives: We described the trends and epidemiological characteristics of varicella outbreaks from 2016 to 2020 in the Republic of Korea.

Methods: We investigated variables such as the outbreak setting, age of patients, vaccination status, and lesion count. The collected data were analyzed with the Cochrane-Armitage trend test and Kruskal-Wallis test. Read More

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Health impact of seven herpesviruses on (pre)diabetes incidence and HbA: results from the KORA cohort.

Diabetologia 2022 May 11. Epub 2022 May 11.

Institute of Medical Information Sciences, Biometry and Epidemiology, Ludwig-Maximilians University, Munich, Germany.

Aims/hypothesis: The prevalence of type 2 diabetes is increasing worldwide, and previous studies have suggested that it is higher in individuals who are seropositive for herpesviruses. This study examines the prospective association of herpesviruses with (pre)diabetes to evaluate their potential role in diabetes aetiology.

Methods: Two follow-up examinations of the German population-based KORA cohort (F4 and FF4) were used to identify participants with normal glucose tolerance at baseline, thus being at risk for (pre)diabetes (n = 1257). Read More

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Vaccination in Pediatric Patients with Sickle-Cell Disease: Uptake Report and Mini-Review.

J Trop Pediatr 2022 Apr;68(3)

Pediatric Infectious Diseases, Santa Casa de São Paulo, São Paulo 01221-010, Brazil.

Background: Brazil has one of the highest numbers of births with sickle-cell disease (SCD) in the Americas. Despite the risk of severe illnesses and death due to both vaccine-preventable infections, vaccination uptake in pediatric patients with SCD is unknown.

Material And Methods: Children under 18 years with SCD presenting to routine medical consultations had their vaccination status evaluated according to the national recommendations. Read More

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Viral Pneumonias.

Radiol Clin North Am 2022 May;60(3):383-397

Department of Radiology, MSC 10 5530, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA.

Viral pneumonia is usually community acquired and caused by influenza, parainfluenza, respiratory syncytial virus, human metapneumovirus, and adenovirus. Many of these infections are airway centric and chest imaging demonstrates bronchiolitis and bronchopneumonia, With the exception of adenovirus infections, the presence of lobar consolidation usually suggests bacterial coinfection. Community-acquired viral pathogens can cause more severe pneumonia in immunocompromised hosts, who are also susceptible to CMV and varicella infection. Read More

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Case Report: Unusual Varicella-Zoster Virus Meningoencephalitis With Meningomyelitis Mimicking Central Nervous System Leukemia.

Front Med (Lausanne) 2022 20;9:847219. Epub 2022 Apr 20.

Department of Neurology, The Second Xiangya Hospital of Central South University, Changsha, China.

Background: Varicella-Zoster Virus (VZV) is a human pathogen from the α-subfamily of herpesviruses. In immunocompromised patients, VZV may produce disease of the central nervous system (CNS). Clinical manifestations of CNS infection with VZV are non-specific and can mimic other infectious and non-infectious diseases. Read More

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Short-Term Spinal Cord Stimulation or Pulsed Radiofrequency for Elderly Patients with Postherpetic Neuralgia: A Prospective Randomized Controlled Trial.

Neural Plast 2022 27;2022:7055697. Epub 2022 Apr 27.

Department of Pain Management, The State Key Clinical Specialty in Pain Medicine, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.

Background: Postherpetic neuralgia (PHN) is the most common and severe complication after varicella-zoster infection, especially in elderly patients. PHN is always refractory to treatment. Both pulsed radiofrequency (PRF) and short-term spinal cord stimulation (stSCS) have been used as effective analgesia methods in clinic. Read More

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Regulation of Siglec-7-mediated varicella-zoster virus infection of primary monocytes by cis-ligands.

Biochem Biophys Res Commun 2022 Apr 26;613:41-46. Epub 2022 Apr 26.

Department of Immunochemistry, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0081, Japan; WPI Immunology Frontier Research Center, Osaka University, 3-1 Yamadaoka, Suita, Osaka, 565-0081, Japan; Center for Infectious Disease Education and Research, Osaka University, Osaka, 565-0871, Japan. Electronic address:

Varicella-zoster virus (VZV) first infects hematopoietic cells, with the infected cells then acting to distribute the virus throughout the body. Sialic acid-binding immunoglobulin-like lectin (Siglec) family molecules recognize sialic acid-containing molecules on the same cell surface, called cis-ligands, or molecules on other cells or soluble agents, called trans-ligands. Among the Siglec family molecules, Siglec-4 and Siglec-7 mediate VZV infection through association with glycoprotein B (gB). Read More

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