998 results match your criteria Pediatrics Appendicitis

[Application of ultrasound-guided endoscopic retrograde appendicitis therapy in children with appendix-related chronic abdominal pain].

Zhongguo Dang Dai Er Ke Za Zhi 2022 Apr;24(4):360-365

Department of Pediatrics, Tangdu Hospital, Air Force Military Medical University, Shaanxi, Xi'an 710038, China.

Objectives: To study the clinical efficacy of ultrasound-guided endoscopic retrograde appendicitis therapy in children with appendix-related chronic abdominal pain.

Methods: A retrospective analysis was performed on the medical data of 30 children with the chief complaint of chronic abdominal pain who were admitted from August 2019 to May 2021. All the children were found to have inflammation of the appendix or intracavitary stool and fecalith by ultrasound and underwent ultrasound-guided endoscopic retrograde appendicitis therapy. Read More

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Hyponatremia as a predictor of complicated appendicitis in children: A systematic review and meta-analysis.

Asian J Surg 2022 Apr 27. Epub 2022 Apr 27.

Department of Pediatric Surgery, Hangzhou Children's Hospital. Hangzhou, China. Electronic address:

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Diagnostics and treatment of complications of SARS-CoV-2 infection in the pediatric surgery department. An analysis based on seven clinical cases and literature review.

Pol Przegl Chir 2022 Apr;94(2):5-11

Department and Clinic of Pediatric Surgery, Traumatology and Urology, Poznan University of Medical Sciences, Poland.

<b> Introduction:</b> Pediatric inflammatory multisystem syndrome - temporally associated with SARS-CoV-2 (PIMS-TS) is a new disease, the first cases of which were observed in the spring of 2020. It affects children who have been infected with SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus 2) and children who have been in direct contact with patients suffering from COVID-19 (coronavirus disease 2019). The disease is characterized by a wide spectrum of symptoms and the development of generalized inflammation of different organs and systems. Read More

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Clinical, Laboratory and Radiographic Features Associated With Prolonged Hospitalization in Children With Complicated Appendicitis.

Front Pediatr 2022 6;10:828748. Epub 2022 Apr 6.

Pediatric Infectious Disease, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY, United States.

Objective: In children with appendicitis, rupture of the appendix is associated with a significant increase in morbidity. We sought to characterize the spectrum of illness in children with complicated appendicitis and to define those factors associated with a longer hospital stay.

Study Design: We conducted a retrospective review of 132 children, 18 years of age or younger at a large urban teaching hospital in the Bronx, NY between October 2015 and April 2018 with an intraoperative diagnosis of perforated appendix. Read More

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Pediatric appendicitis in the time of the COVID-19 pandemic: A retrospective chart review.

J Am Coll Emerg Physicians Open 2022 Apr 19;3(2):e12722. Epub 2022 Apr 19.

Department of Surgery and Perioperative Care Division of Pediatric Surgery Dell Children's Medical Center University of Texas Austin Texas USA.

Aim: Conduct a time trend analysis that describes 2 groups of patients admitted to a large tertiary children's hospital that presented with appendicitis and determine if there was an increase in complicated appendicitis when compared between 2 time periods before and during the early coronavirus disease 2019 (COVID-19) pandemic of 2020.

Methods: We conducted a retrospective analysis of all children presenting to a single-center site with appendicitis between March 23 and August 31, 2020, in the Central Texas region. We compared 507 patients presenting with appendicitis from the non-COVID-19 era in 2019 with n = 249 to patients presenting during the COVID time period with n = 258. Read More

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Acute promyelocytic leukemia presenting with acute appendicitis and coagulopathy in a pediatric patient: A previously unreported site of extramedullary disease.

Pediatr Blood Cancer 2022 Apr 22:e29703. Epub 2022 Apr 22.

Department of Pediatrics, Division of Hematology and Oncology, Atrium Health at Charlotte, Charlotte, North Carolina, USA.

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Nonoperative Management of Uncomplicated Appendicitis.

Pediatrics 2022 05;149(5)

Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts.

Background And Objectives: Several studies have revealed the success of nonoperative management (NOM) of uncomplicated appendicitis in children. Large studies of current NOM utilization and its outcomes in children are lacking.

Methods: We queried the Pediatric Health Information System database to identify children <19 years of age with a diagnosis code for appendicitis. Read More

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Bronchoabdominal fistula - a severe complication of non-perforated appendicitis.

ANZ J Surg 2022 Apr 13. Epub 2022 Apr 13.

Department of Paediatrics, Gisborne Hospital, Gisborne, New Zealand.

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Criteria-led discharge for simple appendicitis in children: A pilot study.

J Paediatr Child Health 2022 Apr 9. Epub 2022 Apr 9.

Department of Paediatric Surgery and Surgical Simulation, Monash Children's Hospital, Melbourne, Victoria, Australia.

Aim: Criteria-led discharge (CLD) protocols have been suggested to increase efficiency of discharge from hospital following surgical interventions. Our aim was to assess the feasibility, clinical outcomes and parental satisfaction following the introduction of a pilot CLD for simple appendicitis (SA) in children.

Methods: A prospective pilot cohort study was conducted including paediatric patients with SA who were managed with CLD and a control group who were managed with standard discharge procedures. Read More

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Appendiceal involvement in pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): a diagnostic challenge in the coronavirus disease (COVID) era.

Pediatr Radiol 2022 May 8;52(6):1038-1047. Epub 2022 Apr 8.

Academic Unit of Paediatric Radiology, Paediatric X-ray Department, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Oxford Road, Manchester, M13 9WL, UK.

Background: Many studies on pediatric inflammatory multisystem syndrome temporally associated with severe acute respiratory syndrome coronavirus 2 (PIMS-TS) have described abdominal findings as part of multisystem involvement, with limited descriptions of abdominal imaging findings specific to PIMS-TS.

Objective: To perform a detailed evaluation of abdominal imaging findings in children with PIMS-TS.

Materials And Methods: We performed a single-center retrospective study of children admitted to our institution between April 2020 and January 2021 who fulfilled Royal College of Paediatrics and Child Health criteria for PIMS-TS and who had cross-sectional abdominal imaging. Read More

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Intravenous ketorolac versus morphine in children presenting with suspected appendicitis: a pilot single-centre non-inferiority randomised controlled trial.

BMJ Open 2022 Apr 5;12(4):e056499. Epub 2022 Apr 5.

Pediatrics, Stollery Children's Hospital, Edmonton, Alberta, Canada.

Objectives: Despite a lack of evidence demonstrating superiority to non-steroidal anti-inflammatory drugs, like ketorolac, that are associated with lower risk of harms, opioids remain the most prescribed analgesic for acute abdominal pain. In this pilot trial, we will assess the feasibility of a definitive trial comparing ketorolac with morphine in children with suspected appendicitis. We hypothesise that our study will be feasible based on a 40% consent rate. Read More

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MIS-C Case Presented with Acute Appendicitis and Successfully Treated by Plasmapheresis.

Turk Arch Pediatr 2022 Mar;57(2):239-240

Department of Pediatrics, Malatya Training and Research Hospital, Malatya, Turkey.

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Multisystem inflammatory syndrome in children presenting with symptoms of acute appendicitis.

Br J Hosp Med (Lond) 2022 03 17;83(3):1-4. Epub 2022 Mar 17.

Department of Pediatrics, Apollo Hospitals (Unit: International Hospital), Guwahati, India.

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Appendicitis Following Blunt Abdominal Trauma: An Illustrative Case.

R I Med J (2013) 2022 Apr 1;105(3):37-38. Epub 2022 Apr 1.

Assistant Professor of Pediatrics, Assistant Professor of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, RI.

Acute appendicitis is the most common abdominal surgical emergency, with an average of 7-9% of individuals developing the condition within their lifetime.1 While cases of acute traumatic appendicitis are rare, medical literature supports their plausibility with the most famous case stretching back to the controversial 1926 death of stunt performer, Harry Houdini. Several mechanisms have been proposed by which blunt abdominal trauma results in acute appendicitis. Read More

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Postoperative Pneumoperitoneum in Pediatric Patients: Residual Air or Surgical Complication? A Prospective Study.

J Laparoendosc Adv Surg Tech A 2022 May 28;32(5):576-582. Epub 2022 Mar 28.

Department of Pediatric Surgery and Hospital Universitario La Paz, Madrid, Spain.

Residual postoperative pneumoperitoneum (RPP) can be confused with postoperative complications. Our aim was to study RPP characteristics in pediatric patients. Prospective study in children with noncomplicated appendicitis, from July to December 2019, divided into open appendectomy (OA) or laparoscopic appendectomy (LA). Read More

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Operative Time Is Independently Associated With Morbidity in Pediatric Complicated Appendicitis.

J Surg Res 2022 Mar 24;276:143-150. Epub 2022 Mar 24.

Department of Pediatric Surgery, Cook Children's Hospital, Fort Worth, Texas. Electronic address:

Introduction: Complicated appendicitis is a common cause of morbidity in children. Studies have analyzed the risk factors in the surgical treatment of this pathology, including obesity and disease severity, but not operative time (OT). We hypothesize that OT is independently associated with increased morbidity for children with complicated appendicitis. Read More

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Digestive outcomes in Cystic fibrosis.

Best Pract Res Clin Gastroenterol 2022 Feb-Mar;56-57:101788. Epub 2022 Feb 24.

Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE - Institute for Translational Research in Inflammation, F-59000, Lille, France; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Jeanne de Flandre Children's Hospital, CHU Lille, F-59000, Lille, France. Electronic address:

Cystic fibrosis (CF) is the most frequent life-limiting autosomal recessive disease in Caucasians, affecting the respiratory tract, but also the pancreas, gut, and hepatobiliary tract. CF is caused by variants in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. Prognosis of CF has markedly improved over the last 20 years because of the management in CF centers and recent introduction of CFTR modulators, aimed at correcting the defective CFTR protein. Read More

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A Case of Multisystem Inflammatory Syndrome Due to SARS-CoV-2 Presenting With Acute Appendicitis Symptoms.

Cureus 2022 Feb 14;14(2):e22206. Epub 2022 Feb 14.

Department of Pathology, Konya City Hospital, Konya, TUR.

Multisystem Inflammatory Syndrome (MIS-C) in children associated with SARS-CoV-2 infection has a variable clinical presentation because it affects many systems. It can affect the cardiac, renal, respiratory, hematological, gastrointestinal, dermatological, and neurological systems. If left untreated, it causes fatal complications. Read More

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February 2022

The rising appendicitis mimicker: A case report of Multisystem Inflammatory Syndrome in Children presenting with acute abdomen.

SAGE Open Med Case Rep 2022 5;10:2050313X221082903. Epub 2022 Mar 5.

El-Demerdash Hospital, Ain Shams University, Cairo, Egypt.

We describe a case of post-coronavirus disease 2019 (COVID-19) multisystem inflammatory syndrome in children (MIS-C). The 12-year-old child presented with appendicitis-like symptoms in the form of gradually worsening abdominal pain localizing over the right iliac fossa, fever, and vomiting. After an appendectomy, the abdominal pain did not resolve. Read More

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Complicated Pylephlebitis Secondary to Perforated Appendicitis in an Adolescent.

J Indian Assoc Pediatr Surg 2022 Jan-Feb;27(1):115-117. Epub 2022 Jan 11.

Department of Pediatric Gastroenterology and Hepatology, Indraprastha Apollo Hospital, New Delhi, India.

Septic thrombophlebitis of the portal vein or pylephlebitis is a rare cause of morbidity and mortality in children. The common causes include infective intra-abdominal pathology (acute appendicitis or diverticulitis) or inflammatory conditions (acute pancreatitis and inflammatory bowel disease). Management involves a multidisciplinary team approach for favorable outcome. Read More

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January 2022

Refining sonographic criteria for paediatric appendicitis: combined effects of age-based appendiceal size and secondary findings.

Emerg Med J 2022 Mar 7. Epub 2022 Mar 7.

Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts, USA.

Objective: Appendiceal diameter is a primary sonographic determinant of paediatric appendicitis. We sought to determine if the diagnostic performance of outer appendiceal diameter differs based on age or with the addition of secondary sonographic findings.

Methods: We retrospectively reviewed patients aged less than 19 years who presented to the Boston Children's Hospital ED and had an ultrasound (US) for the evaluation of appendicitis between November 2015 and October 2018. Read More

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Factors affecting utilization of CT scan following ultrasound evaluation of suspected appendicitis.

J Osteopath Med 2022 Mar 3. Epub 2022 Mar 3.

Department of Pediatrics, St. Christopher's Hospital for Children, Philadelphia, PA, USA.

Context: When evaluating a pediatric patient in the emergency department for suspected appendicitis, a provider is often faced with the dilemma of deciding if a computed tomography (CT) scan is warranted when-as is most often the case-ultrasound results do not yield a definitive diagnosis. The potential risks of radiation must be weighed against numerous aspects of a patient's background, physical exam, and already-obtained workup.

Objectives: This study aims to aid in future decision making of providers in their evaluation of patients with suspected appendicitis, to help facilitate a more comprehensive answer to the "next-steps" in the question of equivocal ultrasound, and to create a pathway utilizing lab results, physical exam findings, and pertinent positives and negatives in patient history to facilitate a more objective decision-making process for ordering a CT scan. Read More

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Impact of the COVID-19 Pandemic on the Pediatric Hospital Visits: Evidence from the State of Florida.

Pediatr Rep 2022 Feb 1;14(1):58-70. Epub 2022 Feb 1.

Department of Industrial and Management Systems Engineering, University of South Florida, Tampa, FL 33612, USA.

Although early evidence reported a substantial decline in pediatric hospital visits during COVID-19, it is unclear whether the decline varied across different counties, particularly in designated Medically Underserved Areas (MUA). The objective of this study is to explore the state-wide impact of COVID-19 on pediatric hospital visit patterns, including the economic burden and MUA communities. We conducted a retrospective observational study of pediatric hospital visits using the Florida State all-payer Emergency Department (ED) and Inpatient dataset during the pandemic (April-September 2020) and the same period in 2019. Read More

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February 2022

Appendicitis as a Leading Manifestation of Kawasaki Disease in Older Children.

Children (Basel) 2022 Feb 2;9(2). Epub 2022 Feb 2.

Department of Pediatrics, Hsinchu MacKay Memorial Hospital, Hsinchu City 30071, Taiwan.

Kawasaki disease (KD) is a systematic inflammatory disease with multiple organ involvement. Timely diagnosis and prompt management are essential for successful treatment. KD, with an atypical presentation, remains a diagnostic challenge for physicians. Read More

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February 2022

Current Practice and Pitfalls of Select Biomarkers in the Emergency Care of Children.

Landon A Jones

Pediatr Emerg Med Pract 2022 Mar 2;19(3):1-24. Epub 2022 Mar 2.

Associate Professor; Program Director, Pediatric Emergency Medicine Fellowship, Makenna David Pediatric Emergency Center; Department of Emergency Medicine & Pediatrics, University of Kentucky, Lexington, KY.

Specific biomarker levels can help differentiate children who require emergent medical interventions, such as procedures, surgeries, or antibiotics, from those who may not. Appropriate application of biomarkers after a thorough history and physical examination can potentially improve cost-effective management by minimizing unnecessary procedures and tests without sacrificing patient safety. This issue reviews the literature regarding 4 biomarkers: lactate, C-reactive protein, ferritin, and procalcitonin. Read More

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Association Between Neighborhood-Level Social Determinants of Health and Access to Pediatric Appendicitis Care.

JAMA Netw Open 2022 02 1;5(2):e2148865. Epub 2022 Feb 1.

Departments of Surgery and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Importance: Presenting with complicated appendicitis, which is associated with higher rates of complications and readmissions compared with simple appendicitis, may indicate delayed access to care. Although both patient-level and neighborhood-level social determinants of health are associated with access to care, little is known about the association between neighborhood factors and access to acute pediatric surgical care.

Objective: To examine the association between neighborhood factors and the odds of presenting with complicated appendicitis and unplanned postdischarge health care use. Read More

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February 2022

Diagnostic accuracy of ultrasound in the paediatric population with acute right iliac fossa pain, our District General Hospital experience.

Ulster Med J 2022 Jan 11;91(1):26-29. Epub 2022 Feb 11.

Department of General Surgery, Tameside and Glossop Integrated Care NHS Foundation Trust, Ashton-Under-Lyne, OL6 9RW, United Kingdom.

Aim: This project aimed to evaluate the role of ultrasound scan (USS) in children presenting with acute onset right iliac fossa (RIF) pain and suspected appendicitis.

Methods: We retrospectively studied 100 consecutive children undergoing USS for RIF pain. Children with low to moderate clinical probability of appendicitis were seen by the surgical team and subsequently underwent USS by a radiologist or a sonographer with a special interest in paediatric USS. Read More

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January 2022

Childhood neuroendocrine tumors of the digestive system: A single center experience.

İbrahim Kartal

Medicine (Baltimore) 2022 Feb;101(6):e28795

Ondokuz Mayis University, Faculty of Medicine, Department of Pediatrics, Division of Pediatric Hematology-Oncology, Samsun, Turkey.

Abstract: The prevalence and incidence of neuroendocrine tumors (NETs) are increasing in the pediatric population. This increase can be associated with improved diagnostics and increased detection rates of the disease. We aimed to discuss the clinical and pathological characteristics of patients with this rare disease who were followed and treated at our center. Read More

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February 2022

Factors Contributing to Nonvisualization of the Appendix on Ultrasound in Children With Suspected Appendicitis.

Pediatr Emerg Care 2022 Feb;38(2):e678-e682

Cooper Research Institute, Cooper University Hospital, Camden, NJ.

Objective: This study aimed to identify the patient characteristics, history factors, physical examination findings, and sonographic findings, which contribute to a higher risk of the appendix not being visualized on ultrasound evaluation (ie, nondiagnostic or equivocal study) in patients being evaluated for appendicitis. Secondarily, this study assessed the utility of an equivocal ultrasound, specifically in the ability to predict the absence of appendicitis.

Methods: A retrospective case review was performed, of children (age, 0-18 years) presenting to a pediatric emergency department with clinical suspicion for appendicitis, who underwent sonographic studies during the 12-month study period. Read More

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February 2022