880 results match your criteria Pediatrics Appendicitis


The impact of intravenous acetaminophen pricing on opioid utilization and outcomes for children with appendicitis.

Surgery 2021 May 10. Epub 2021 May 10.

Division of Pediatric Surgery, Children's Hospital Los Angeles, CA Department of Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA; Department of Preventive Medicine, University of Southern California, Los Angeles, CA. Electronic address:

Background: In 2014, the price of intravenous acetaminophen more than doubled. This study determined whether increased intravenous acetaminophen cost was associated with decreased utilization and increased opioid use for children undergoing appendectomy.

Methods: A multicenter retrospective cohort study using the Pediatric Health Information System database between 2011 and 2017 was performed. Read More

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Predictors of Clinical Outcomes in Pediatric Appendicitis: Role of the Individual Sonographer and Radiologist When Using a First-Line Ultrasound Approach.

J Am Coll Radiol 2021 Apr 29. Epub 2021 Apr 29.

Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Department of Radiology, University of Cincinnati College of Medicine, Cincinnati, Ohio.

Objective: To determine if differences between individual sonographers and radiologists performing and interpreting appendix ultrasound affect clinically important outcomes in children with suspected acute appendicitis.

Methods: Patients less than 18 years of age who presented to our emergency department with suspected acute appendicitis and underwent an appendix ultrasound were identified. Sonographers who performed fewer than 100 examinations and radiologists who interpreted fewer than 100 examinations during the study period were excluded. Read More

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Acute Appendicitis in Multisystem Inflammatory Syndrome.

Indian J Pediatr 2021 Apr 27. Epub 2021 Apr 27.

Department of Pediatrics, Rainbow Children's Hospital, Bannerghatta Road, Bangalore, 560076, India.

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Variation in imaging outcomes associated with individual sonographers and radiologists in pediatric acute appendicitis: a retrospective cohort of 9271 examinations.

Eur Radiol 2021 Apr 21. Epub 2021 Apr 21.

Department of Radiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Objective: To determine if individual sonographers and radiologists impact appendix visualization by ultrasound and utilization of computed tomography (CT) in children with suspected acute appendicitis.

Materials And Methods: Appendix ultrasound examinations performed at Cincinnati Children's Hospital Medical Center on Emergency Department patients ≤ 18 years old were retrospectively identified. Examinations performed/interpreted by sonographers/radiologists with fewer than 100 examinations were excluded. Read More

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Bilateral pheochromocytoma revealed by acute abdominal pain in a child. A case report.

Pediatr Endocrinol Diabetes Metab 2021 Apr 15. Epub 2021 Apr 15.

Department of Pediatrics, University Hospital Farhat Hached, Sousse, Tunisia.

Pheochromocytoma is a rare tumor during childhood, originating from the chromafine tissue. The clinical presentation can be variable and assembling many other diseases. This tumor submits specific care problems. Read More

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Multisystem inflammatory syndrome in children. An emerging clinical challenge for pediatric surgeons in the COVID 19 era.

J Pediatr Surg Case Rep 2021 Jun 8;69:101838. Epub 2021 Apr 8.

Department of Pediatrics, Santobono Pausilipon Children's Hospital, Naples, Italy.

Background/purpose: Multisystem inflammatory syndrome in children (MIS-C) is a potentially life-threatening condition occurring 2-6 weeks after Coronavirus disease 2019 (COVID-19) in previously healthy children and adolescents, characterized by clinical and laboratory evidence of multiorgan inflammation. We reported the case of a 6-year-old child presented with acute abdomen and then diagnosed with MIS-C. In addition, to better portray this new entity, we performed a systematic review of MIS-C gastrointestinal features and particularly on those mimicking surgical emergencies. Read More

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Prognosis of ultrasonographic low-grade pediatric appendicitis treated with supportive care.

Surgery 2021 Apr 6. Epub 2021 Apr 6.

Department of General Pediatrics, Tokyo Metropolitan Children's Medical Center, Tokyo, Japan.

Background: A previous report proposed ultrasonography-based classification as a promising means of predicting pediatric spontaneously resolving appendicitis. The present study investigated the long-term prognosis of supportive care for low-grade appendicitis identified by ultrasonography, defined as an appendix with a smooth submucosal layer irrespective of blood flow or an appendix with an irregular layer and increased blood flow.

Methods: The present, retrospective cohort study enrolled patients under 16 years of age with acute appendicitis at a children's hospital between October 2010 and September 2016. Read More

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Correction: Quarantine and Appendicitis: A Macro-Area Experience.

Pediatr Gastroenterol Hepatol Nutr 2021 Mar 4;24(2):244. Epub 2021 Mar 4.

Department of Surgery, Woman and Child Hospital, Dentistry, Paediatrics and Gynecology; Division of Pediatric Surgery, University of Verona, Verona, Italy.

[This corrects the article on p. 75 in vol. 24, PMID: 33505896. Read More

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Comparison of Clinical Characteristics According to the Existence of Secondary Appendicitis in Pediatric Acute Enterocolitis: A Single Center Study.

Authors:
So Yoon Choi

Pediatr Gastroenterol Hepatol Nutr 2021 Mar 4;24(2):127-134. Epub 2021 Mar 4.

Department of Pediatrics, Kosin University College of Medicine, Kosin University Gospel Hospital, Busan, Korea.

Purpose: In patients with acute enterocolitis, radiologic findings are sometimes accompanied by secondary inflammation of the appendix. The purpose of this study was to evaluate the clinical features of acute enterocolitis with secondary inflammation of the appendix.

Methods: Medical records from patients who underwent abdominal ultrasonography or computed tomography (CT) among those admitted for acute enterocolitis were retrospectively reviewed. Read More

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Pediatric radiologic manifestations of COVID-19.

Clin Imaging 2021 Mar 30;75:165-170. Epub 2021 Mar 30.

Department of Radiology, University of Washington and Seattle Children's Hospital, 4800 Sand Point Way NE, Seattle, WA 98105, United States of America.

Purpose: While full description of pediatric COVID-19 manifestations is evolving, children appear to present less frequently, and often display a less severe disease phenotype. There is correspondingly less data regarding pediatric radiologic findings. To describe the imaging findings of pediatric COVID-19, we evaluated the radiologic imaging of the initial patient cohort identified at our institution. Read More

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How COVID-19 pandemic influences paediatric acute appendicitis cases?

Orv Hetil 2021 04 7;162(16):608-610. Epub 2021 Apr 7.

1 Heim Pál Országos Gyermekgyógyászati Intézet, Sebészeti és Traumatológiai Osztály, Budapest, Üllői út 86., 1089.

Összefoglaló. Bevezetés: A COVID-19-pandémia miatt a gyermekkori appendicitisek kezelésében számos változás történt (laparoszkópia helyett nyílt műtét, antibiotikumkezelés). Világszerte emelkedett a szövődményes appendicitisek aránya. Read More

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Impact of SARS-CoV-2 pandemic on emergency department activity at the pediatric surgery unit of a third-level hospital.

Cir Pediatr 2021 Apr 1;34(2):85-89. Epub 2021 Apr 1.

Pediatric Surgery Unit. La Paz Pediatric Hospital, Madrid (Spain). La Paz Biomedical Research Institute (IdiPaz), Maternal, Child, and Development Health (SAMID) network.

Introduction: As a result of the emergence of the SARS-CoV-2 respiratory virus in Wuhan in December 2019, the Spanish Government declared the state of emergency with restrictions such as stay-at-home lockdown. The objective of this study was to analyze emergency activity at a referral pediatric surgery unit in its territory and determine whether surgical pathologies had decreased or not.

Methods: A retrospective study of pediatric patients presenting at the emergency department and referred to the pediatric surgery unit from March 14, 2020 to April 20, 2020 was carried out. Read More

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Gender specific data in patients with acute appendicitis: a single center perspective.

Minerva Pediatr (Torino) 2021 Apr 2. Epub 2021 Apr 2.

Division of Pediatric Surgery, Department of Surgery, Dentistry, Paediatrics and Gynecology, Woman & Child Hospital, University of Verona, Verona, Italy.

Background: The influence of sex, socioeconomic status and other factors on outcomes from acute illness has been found recently with an increasing interest; acute appendicitis is the most frequent urgency in pediatric age. The aim of this study is to show any gender differences.

Materials And Methods: We retrospectively analysed the medical records of consecutive patients who underwent surgical exploration for acute appendicitis. Read More

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Optimal initial antibiotic regimen for the treatment of acute appendicitis: a systematic review and network meta-analysis with surgical intervention as the common comparator.

J Antimicrob Chemother 2021 Apr 1. Epub 2021 Apr 1.

Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan.

Background: The optimal antibiotic regimen for the medical management of acute appendicitis remains unknown due to a lack of head-to-head comparisons between different antibiotic regimens.

Methods: We systematically searched the PubMed, EMBASE, Scopus and Cochrane Central Register of Controlled Trials databases from their inception through to August 2020. We selected randomized controlled trials (RCTs) or observational studies comparing antibiotic therapy and appendectomy as the initial treatment for adult or paediatric patients with acute appendicitis. Read More

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Incidence of appendicitis during SARS-CoV-2 pandemic quarantine.

Pediatr Int 2021 04 31;63(4):484-485. Epub 2021 Mar 31.

Division of Pediatric Surgery, Department of Surgery, Dentistry, Paediatrics and Gynecology, Woman and Child Hospital, University of Verona, Verona, Italy.

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Spatial-temporal clusters of pediatric perforated appendicitis in California.

J Pediatr Surg 2021 Feb 22. Epub 2021 Feb 22.

Division of Emergency Medicine, Department of Pediatrics, Rady Children's Hospital San Diego/University of California San Diego, 3020 Children's Way, MC5075 - Emergency Medicine, San Diego, CA 92123, United States. Electronic address:

Background: Perforated appendicitis is a well-documented child health disparity. Geographic patterns in perforated appendicitis exist in several United States regions, but such patterns have not been described in California. We aimed to analyze spatial-temporal patterns of pediatric perforated appendicitis and identify population characteristics contributing to these cluster patterns. Read More

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February 2021

The Use of Fecal Calprotectin Testing in Paediatric Disorders: A Position Paper of the European Society for Paediatric Gastroenterology and Nutrition Gastroenterology Committee.

J Pediatr Gastroenterol Nutr 2021 Apr;72(4):617-640

Neurogastroenterology and Motility, UCL Great Ormond Street Institute of Child Health and Department of Gastroenterology, Great Ormond Street Hospital, London, UK.

Objectives: The aim of the study was to review the evidence regarding the clinical use and value of fecal calprotectin (FC) measurements in different gastrointestinal disorders in children.

Methods: A literature search was conducted in the PubMed, MEDLINE, EMBASE, and Cochrane databases until October 31, 2019. Subtopics were identified and each assigned to individual authors. Read More

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Sonographic imaging of appendiceal orifice polyps in children.

J Clin Ultrasound 2021 Mar 6. Epub 2021 Mar 6.

Department of Pediatric Surgery, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou, P.R. China.

Although gastrointestinal polyps are a common disease, appendiceal orifice polyps are rare and usually found incidentally during autopsy or surgery. Data on the sonographic features of appendiceal orifice polyps in children are limited. We describe the sonographic features of appendiceal orifice polyps in two children. Read More

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Acute Appendicitis in Children During the COVID-19 Pandemic: Neither Delayed Diagnosis Nor Worse Outcomes.

Pediatr Emerg Care 2021 Mar;37(3):185-190

Pediatric Surgery, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Aim: The aim of this study was to describe the incidence of complicated appendicitis during the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic lockdown.

Methods: This was a retrospective study of pediatric patients diagnosed with acute appendicitis in a single pediatric institution that assumed care responsibility for most of the pediatric emergencies during the lockdown period in Madrid (Spain). A control group was made up of the same number of patients diagnosed the previous year. Read More

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Magnetic Resonance Imaging Provides Useful Diagnostic Information Following Equivocal Ultrasound in Children With Suspected Appendicitis.

Can Assoc Radiol J 2021 Mar 1:846537121993797. Epub 2021 Mar 1.

Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.

Purpose: In Canada, ultrasonography is the primary imaging modality for children with suspected appendicitis, yet equivocal studies are common. Magnetic resonance imaging provides promise as an adjunct imaging strategy. The primary objective of this study was to determine the proportion of children with suspected appendicitis and equivocal ultrasound where magnetic resonance imaging determined a diagnosis. Read More

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International Core Outcome Set for Acute Simple Appendicitis in Children: Results of A Systematic Review, Delphi Study, and Focus Groups with Young People.

Ann Surg 2020 Dec 29. Epub 2020 Dec 29.

*Department of Pediatric Surgery, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam & Vrije Universiteit, Amsterdam, The Netherlands †University Surgery Unit, Faculty of Medicine, University of Southampton, Southampton General Hospital, Southampton, UK; Department of Paediatric Surgery and Urology, Southampton Children's Hospital, Southampton, UK ‡Parent and Patient representative, USA §Pediatric clinical Research Office, Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands ¶Knowledge Institute of the Dutch Association of Medical Specialists, Utrecht, The Netherlands ||Child Health Evaluative Sciences, The Hospital for Sick Children Research Institute, Toronto, Canada **Center for Surgical Outcomes Research, Abigail Wexner Research Institute and Department of Surgery, Nationwide Children's Hospital, Columbus, OH, USA ††Department of Pediatric Surgery, Karolinska University Hospital, Stockholm, Sweden; Department of Women's and Children's Health, Karolinska Institute, Stockholm, Sweden ‡‡Department of Surgery, Children's Mercy Hospital, Kansas City, MO, USA §§Department of Pediatric Surgery, Sydney Children's Hospital, Randwick, NSW, Australia, School of Women's and Children's Health, University of New South Wales ¶¶Department of Pediatric Surgery, KK Women's and Children's Hospital, Singapore, Singapore ||||Division of Paediatric Surgery, Department of Surgery, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia ***Department of Pediatric Surgery, British Columbia Children's Hospital, Vancouver, BC, Canada †††Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, ON, Canada ‡‡‡Department of Surgery, University of Toronto, Toronto, ON, Canada §§§Harvey E. Beardmore Division of Pediatric Surgery, Montreal Children's Hospital, Montreal, QC, Canada ¶¶¶Department of Pediatric Surgery, Helsinki Children's Hospital, Helsinki, Finland ||||||Department of Pediatric Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia ****Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Canada.

Objective:: To develop an international Core Outcome Set (COS), a minimal collection of outcomes that should be measured and reported in all future clinical trials evaluating treatments of acute simple appendicitis in children.

Summary Background Data: A previous systematic review identified 115 outcomes in 60 trials and systematic reviews evaluating treatments for children with appendicitis, suggesting the need for a COS.

Methods: The development process consisted of four phases: (1) an updated systematic review identifying all previously reported outcomes, (2) a two-stage international Delphi study in which parents with their children and surgeons rated these outcomes for inclusion in the COS, (3) focus groups with young people to identify missing outcomes, and (4) international expert meetings to ratify the final COS. Read More

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December 2020

Resource Use by Hospital Type for Frequent Inpatient Pediatric Conditions.

Hosp Pediatr 2021 Mar;11(3):287-292

Department of Pediatrics, and.

Background: Children's hospitals (CHs) deliver care to underserved, critically ill, and medically complex patients. However, non-CHs care for the majority of children with frequently occurring conditions. In this study, we aimed to examine resource use across hospitals where children receive care for frequent inpatient conditions. Read More

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[Cross-sectional study of the clinical characteristics and outcomes of children hospitalized with COVID-19 in Lima, Peru].

Medwave 2021 Jan 20;21(1):e8107. Epub 2021 Jan 20.

Departamento de Pediatría, Centro de Ciencias de la Salud de la Universidad de Texas en Houston, Estados Unidos. ORCID: 0000-0001-5349-5260.

Introduction: Coronavirus 2019 (SARS-CoV-2) infection in children occurred in Peru as of March 2020, leading to pediatric patients' hospitalization in areas adapted for this purpose at the Edgardo Rebagliati Martins National Hospital. In the beginning, the demand for hospitalization was low, but it increased gradually. Consistent with international reports, the majority of patients presented mild or moderate symptoms. Read More

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January 2021

An Administrative Data-based Surrogate Definition Identifies Children Evaluated Beyond Physical Examination for Suspected Appendicitis.

Pediatr Qual Saf 2020 Nov-Dec;5(6):e343. Epub 2020 Oct 23.

Department of Surgery, University of Utah, Salt Lake City, Utah.

Previous studies have reported on the evaluation of patients diagnosed with appendicitis. Very little is known about all patients evaluated for suspected appendicitis. Patients evaluated beyond physical examination with laboratory and imaging testing, then found not to have appendicitis, are more difficult to identify. Read More

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October 2020

Determining the impact of body mass index on ultrasound accuracy for diagnosing appendicitis: Is it less useful in obese children?

J Pediatr Surg 2021 Jan 30. Epub 2021 Jan 30.

Division of Pediatric Surgery, Department of Surgery, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, TN, United States; Department of Pediatric Surgery, Section of Surgical Sciences, Vanderbilt University Medical Center, Nashville, TN, United States. Electronic address:

Background: Ultrasonography (US) is the preferred imaging for suspected pediatric appendicitis. We hypothesize that children with elevated Body-Mass-Index-for-age percentile (BMIP) may be more likely to have an inaccurate or equivocal (IE) US.

Methods: After IRB approval, a four-year review was performed on pediatric patients evaluated for appendicitis by US. Read More

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January 2021

Epiploic Appendagitis and Omental Infarction as Rare Causes of Acute Abdominal Pain in Children.

Pediatr Rep 2021 Feb 5;13(1):76-85. Epub 2021 Feb 5.

Pediatric Unit, Department of Pediatrics, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.

Omental infarction and epiploic appendagitis are rare causes of acute abdominal pain in the pediatric population. Radiological evaluation is necessary to establish a specific diagnosis and to differentiate appendicitis from these conditions as they can be often managed conservatively without surgical intervention. Read More

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February 2021

Diagnostic Value of Clinical Prediction Scores for Acute Appendicitis in Children Younger than 4 Years.

Eur J Pediatr Surg 2021 Feb 7. Epub 2021 Feb 7.

Department of Pediatrics and Neonatology, Hospital Privado Universitario de Córdoba, Córdoba, Argentina.

Introduction:  Acute appendicitis can be difficult to diagnose, especially in children < 4 years old. The aim of the present study was to assess the diagnostic value of Alvarado score (AS), appendicitis inflammatory response (AIR) score, and pediatric appendicitis score (PAS) in children younger than 4 years.

Materials And Methods:  All children younger than 4 years who underwent appendicectomy between 2005 and 2019 were included retrospectively. Read More

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February 2021

The ongoing impact of COVID-19 on asthma and pediatric emergency health-seeking behavior in the Bronx, an epicenter.

Am J Emerg Med 2021 May 28;43:109-114. Epub 2021 Jan 28.

Division of Pediatric Emergency Medicine, The Children's Hospital at Montefiore, Bronx, NY, United States of America.

Background: The Bronx has the highest prevalence of asthma in the United States (US), and was also an early COVID-19 epicenter, making it a unique study location. Worldwide reports describe significant declines in pediatric emergency department (PED) visits during COVID-19. The ongoing impact of COVID-19 on all PED presentations, including asthma, at an early epicenter has not been studied beyond the pandemic peak and into the early phases of state re-opening. Read More

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Eosinophilic gastroenteritis in an adolescent male with history of chronic bullous disease.

BMJ Case Rep 2021 Feb 4;14(2). Epub 2021 Feb 4.

Division of Allergy and Immunology - Department of Pediatrics, Philippine General Hospital, Manila, Philippines.

Eosinophilic gastroenteritis is a rare inflammatory disorder of the gastrointestinal tract. Although commonly associated with allergic diseases, it is also rarely associated with autoimmune disorders. This case report describes a 17-year-old Filipino male with eosinophilic gastroenteritis, manifesting as abdominal pain, vomiting and diarrhoea. Read More

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February 2021

Acute Appendicitis in Childhood and Adulthood.

Dtsch Arztebl Int 2020 Nov;117(45):764-774

Department of Surgery, Universitäts -medizin Mannheim, Medical Faculty Mannheim, Heidelberg UniversityDepartment of General Pediatrics and Neonatology, Pediatric Gastroenterology, University of Giessen, GermanyDepartment of Pediatric Surgery, University Hospital Frankfurt, Goethe-University Frankfurt am Main, Frankfurt, Germany.

Background: Acute appendicitis is the most common cause of the acute abdomen, with an incidence of 1 per 1000 persons per year. It is one of the main differential diagnoses of unclear abdominal conditions.

Methods: This review is based on pertinent publications that were retrieved by a selective search in the PubMed and Cochrane Library databases. Read More

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November 2020